Issues

• Apple Silicon MPS compatible version, with additionnal improvement

  generatebio/chroma#67 · Filter by author fnachon opened on Jul 3, 2026

• Can you share the structures of the 10 proteins measured with DSC in the paper?

  generatebio/chroma#64 · Filter by author YuuuXie opened on Nov 21, 2025

• Chroma Generates Proteins Longer Than Desired When Using SubstructureConditioner

  generatebio/chroma#63 · Filter by author josefgon00 opened on Mar 19, 2025

• pip install seems to be broken on colab

  generatebio/chroma#62 · Filter by author drumyerscough opened on Jan 23, 2025
  1

• how to prevent collapse when desining symmetric assembly

  generatebio/chroma#61 · Filter by author chiarinival opened on Jan 23, 2025
  2

• which option can let Chroma output a bunch of designed proteins?

  generatebio/chroma#60 · Filter by author ppxwwtaking opened on Jan 22, 2025
  2

• Example of script for binder design

  generatebio/chroma#57 · Filter by author ahof1704 opened on Sep 10, 2024
  1

• Problem in installation

  generatebio/chroma#56 · Filter by author calimbrasti94 opened on Sep 4, 2024
  3

• Refinement of structure?

  generatebio/chroma#55 · Filter by author gezmi opened on Jul 7, 2024

• Conditioning on protein of different length than protein to be designed

  generatebio/chroma#54 · Filter by author vcantuna opened on Jul 3, 2024
  1

• Is the training code available?

  generatebio/chroma#53 · Filter by author LtECoD opened on Jun 11, 2024
  1

• linking downloaded weight for offline chroma usage

  generatebio/chroma#52 · Filter by author peptidelinks opened on May 23, 2024
  10

• Example of training a classifier based on graphclassifier

  generatebio/chroma#51 · Filter by author Zebreu opened on May 20, 2024

• Create functional proteins from a given protein Template/Profile?

  generatebio/chroma#50 · Filter by author Travis13197 opened on May 4, 2024
  1

• Made a few adjustments, please check out. 'samples' issue and batch splitting.

  generatebio/chroma#47 · Filter by author sona9soba opened on Feb 14, 2024
  1

• De-novo binder generation with a hotspot

  generatebio/chroma#43 · Filter by author kushnarang opened on Jan 29, 2024
  1

• Computing the TM score against the PDB dataset

  generatebio/chroma#41 · Filter by author ahof1704 opened on Jan 18, 2024

• Where could I find the code to generate the results in paper fig3 b?

  generatebio/chroma#31 · Filter by author songhe2009 opened on Dec 18, 2023
  1

• Batched conditional generation

  bug
  generatebio/chroma#25 · Filter by author wujiewang opened on Dec 1, 2023

• long time persist model parameters

  generatebio/chroma#15 · Filter by author cyrushu opened on Nov 22, 2023

• Design topology not obeyed

  generatebio/chroma#3 · Filter by author agarrubio opened on Nov 16, 2023