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broncox456/README.md

Cristian Arias, MD

Nephrologist | Internal Medicine Specialist | Healthcare Data Analyst | Bioinformatics | Kidney Disease & Clinical Research

About Me

I am a practicing nephrologist and internal medicine specialist with a strong focus on healthcare data, clinical research, and bioinformatics.

My work combines real-world clinical experience with data analysis to better understand kidney disease, improve decision-making, and explore translational applications of molecular data.

I am particularly interested in bridging clinical medicine with data-driven approaches, including epidemiology, transcriptomics, and multi-omics integration.

Current Focus

  • Chronic Kidney Disease (CKD)
  • Diabetic Kidney Disease (DKD)
  • Glomerular diseases (FSGS, lupus nephritis)
  • Clinical data analysis and epidemiology
  • Multi-omics and translational research

Selected Projects

🔬 DKD Multi-Omics Integration

Integration of kidney transcriptomics and urinary proteomics to explore cross-compartment molecular consistency.

🧬 FSGS RNA-seq Analysis

Transcriptomic analysis focused on fibrosis and inflammatory pathways in disease progression.

🌍 CKD Epidemiology – Dominican Republic

Real-world analysis of CKD in primary care settings, integrating clinical and sociodemographic data.

Technical Skills

  • R (limma, DESeq2)
  • Python (data analysis)
  • SQL
  • Power BI
  • Bioinformatics workflows

Contact

LinkedIn: https://www.linkedin.com/in/cristian-arias-healthcare-data

Pinned Loading

  1. tcga-kirc-multiomics-survival-signature tcga-kirc-multiomics-survival-signature Public

    Integrated analysis of TCGA-KIRC using RNA-seq and RPPA identifies biologically distinct tumor subgroups associated with survival outcomes.

    R

  2. hemodialysis-survival-catheter-vs-fistula-ml hemodialysis-survival-catheter-vs-fistula-ml Public

    Explainable ML model for 1-year mortality prediction in hemodialysis patients, focused on vascular access, inflammation, and clinical risk stratification.

    Python

  3. dkd-multiomics-fibrosis-metabolism-signature dkd-multiomics-fibrosis-metabolism-signature Public

    Multi-omics integration of kidney transcriptomics and urinary proteomics to explore fibrosis, metabolism, and inflammation in diabetic kidney disease (DKD)

    R 1

  4. hemodialysis-intradialytic-hypotension-risk-analysis hemodialysis-intradialytic-hypotension-risk-analysis Public

    Real-world hemodialysis data analysis focused on intradialytic hypotension, clinical risk patterns, and patient-level hemodynamic phenotyping.

    Python

  5. fsgs-rnaseq-fibrosis-inflammation-signature fsgs-rnaseq-fibrosis-inflammation-signature Public

    RNA-seq analysis of fibrosis and inflammation signatures in focal segmental glomerulosclerosis (FSGS)

    R 1

  6. ckd-primary-care-dominican-republic ckd-primary-care-dominican-republic Public

    Real-world analysis of chronic kidney disease (CKD) in primary care in the Dominican Republic, integrating clinical and sociodemographic data with a reproducible Python pipeline.

    Python