Standardized README to Markdown format

README.md

@@ -0,0 +1,57 @@
+# MadSim Model for Motor Pattern Selection
+
+This is the readme for the MadSim model associated with the paper:
+
+Stein W, Straub O, Ausborn J, Mader W, Wolf H. (2008)
+Motor pattern selection by combinatorial code of interneuronal pathways.
+*J Comput Neurosci* 25:543-61
+
+## Abstract/Info
+
+We studied the femur-tibia joint control system of the insect leg, and its switch between resistance reflex in posture control and "active reaction" in walking. The "active reaction" is basically a reversal of the resistance reflex. Both responses are elicited by the same sensory input and the same neuronal network (the femur-tibia network).
+
+The femur-tibia network was modeled by fitting the responses of model neurons to those obtained in animals. Each implemented neuron has a physiological counterpart. The strengths of 16 interneuronal pathways that integrate sensory input were then assigned three different values and varied independently, generating a database of more than 43 million network variants. The uploaded version contains the model that best represented the resistance reflex. Please see below for more help.
+
+We demonstrate that the combinatorial code of interneuronal pathways determines motor output. A switch between different behaviors such as standing to walking can thus be achieved by altering the strengths of selected sensory integration pathways.
+
+## Short Info on Using MadSim Simulator
+
+- Copy the whole `madsim` folder to your hard disk. No installation needed.
+- Madsim files are called `.gui` files. They are ASCII text files containing all parameters of the simulation.
+- Click **File -> Open** to open `.gui` files or use right mouse click to make new neuron / edit properties etc.
+- To display result window in madSim, either select neurons with mouse and press **CTRL + M** or right click on neuron and select **"display diagram window"**.
+- Then press **F1** to start simulation.
+
+Please note that madSim was originally developed in German. The English version has the same capabilities, but may come with translation errors.
+
+**Btw:** MadSim uses HH equations and exponential Euler to calculate ion / synaptic currents.
+
+## Information About the Code
+
+### Neurons in `"stick_insect_FT-simulation_resistance-reflex.gui"`:
+
+#### Sensory neurons in the femoral chordotonal organ:
+
+- 1, 10, 11 = position (+) sensitive
+- 30, 31, 32 = position (-) sensitive
+- 2, 3, 5, 26, 27 = velocity (+) sensitive
+- 8, 9, 12, 28, 29 = velocity (+) sensitive
+
+- 20, 21, 22 = velocity (+) sensitive spiking interneurons
+- 23, 24, 25 = velocity (-) sensitive spiking interneurons
+
+#### Identified interneurons:
+
+- E1 – E10 = identified excitatory nonspiking interneurons
+- I1 – I8 = identified inhibitory nonspiking interneurons
+- IE1 = identified interneuron that inhibits and excites
+
+#### Motor neuron:
+
+- SETi = Slow extensor tibiae motor neuron
+
+The model files were supplied by Wolfgang Stein.
+
+---
+
+2025-06-02: Converted README to Markdown.