Release v2.1.0: spatial retention reconstruction and reproducibility rebuild

[LightChainr]

Summary

This pull request finalizes the validated v2.1.0 release supporting the revised manuscript on progressive stellate-cell occupation of liver scar and contraction of repair interfaces.

Included

• privacy-screened aggregate clinical and flow outputs
• public-data-derived molecular, spatial, mouse, and LINCS results
• coordinate-only UQ biopsy reconstruction and mapping stress tests
• panel-level provenance and methods-audit records
• environment locks and executable reconstruction workflows
• seven main figures and 30 supplementary figures

Validation

• clean Python 3.11 release validation: 46/46 checks passed
• DOI and GitHub metadata synchronized
• release commit: f698b12

Archival record

Version-specific Zenodo DOI: 10.5281/zenodo.22138229

The pull request remains a draft until the Zenodo record is published and final author approvals are complete.