diff --git a/src/detectors/mod.rs b/src/detectors/mod.rs
index c252dd5..697cb71 100644
--- a/src/detectors/mod.rs
+++ b/src/detectors/mod.rs
@@ -384,6 +384,7 @@ impl DetectedRunner {
             }
 
             // Python ecosystem
+            "rye" => vec!["rye".to_string(), "run".to_string(), task.to_string()],
             "uv" => vec!["uv".to_string(), "run".to_string(), task.to_string()],
             "poetry" => vec!["poetry".to_string(), "run".to_string(), task.to_string()],
             "pipenv" => vec!["pipenv".to_string(), "run".to_string(), task.to_string()],
@@ -618,6 +619,13 @@ mod tests {
         assert_eq!(cmd, vec!["bun", "run", "foo"]);
     }
 
+    #[test]
+    fn test_build_command_rye() {
+        let runner = DetectedRunner::new("rye", "pyproject.toml", Ecosystem::Python, 5);
+        let cmd = runner.build_command("start", &[]);
+        assert_eq!(cmd, vec!["rye", "run", "start"]);
+    }
+
     #[test]
     fn test_build_command_pip() {
         let runner = DetectedRunner::new("pip", "requirements.txt", Ecosystem::Python, 8);
diff --git a/src/detectors/python.rs b/src/detectors/python.rs
index 95e041d..cf09b14 100644
--- a/src/detectors/python.rs
+++ b/src/detectors/python.rs
@@ -56,6 +56,18 @@ impl CommandValidator for PythonValidator {
             }
         }
 
+        // Check [tool.rye.scripts] (Rye)
+        if let Some(scripts) = toml_value
+            .get("tool")
+            .and_then(|t| t.get("rye"))
+            .and_then(|p| p.get("scripts"))
+            .and_then(|s| s.as_table())
+        {
+            if scripts.contains_key(command) {
+                return CommandSupport::Supported;
+            }
+        }
+
         // Python is extensible - uv run / poetry run can also execute
         // commands from the virtual environment (pytest, mypy, etc.)
         // So we return Unknown to allow fallback behavior
@@ -64,13 +76,35 @@ impl CommandValidator for PythonValidator {
 }
 
 /// Detect Python package managers
-/// Priority: UV (5) > Poetry (6) > Pipenv (7) > Pip (8)
+/// Priority: UV (5) > Rye (5) > Poetry (6) > Pipenv (7) > Pip (8)
 pub fn detect(dir: &Path) -> Vec<DetectedRunner> {
     let mut runners = Vec::new();
 
-    let has_pyproject = dir.join("pyproject.toml").exists();
+    let pyproject_path = dir.join("pyproject.toml");
+    let has_pyproject = pyproject_path.exists();
     let validator: Arc<dyn CommandValidator> = Arc::new(PythonValidator);
 
+    // Determine if it's a Rye project by inspecting pyproject.toml
+    let mut is_rye = false;
+    if has_pyproject {
+        if let Ok(content) = fs::read_to_string(&pyproject_path) {
+            if let Ok(toml_value) = toml::from_str::<toml::Value>(&content) {
+                is_rye = toml_value.get("tool").and_then(|t| t.get("rye")).is_some();
+            }
+        }
+    }
+
+    // Check for Rye (priority 5)
+    if is_rye {
+        runners.push(DetectedRunner::with_validator(
+            "rye",
+            "pyproject.toml",
+            Ecosystem::Python,
+            5,
+            Arc::clone(&validator),
+        ));
+    }
+
     // Check for UV (priority 5)
     let uv_lock = dir.join("uv.lock");
     if uv_lock.exists() && has_pyproject {
@@ -150,6 +184,27 @@ mod tests {
         assert_eq!(runners[0].name, "uv");
     }
 
+    #[test]
+    fn test_detect_rye() {
+        let dir = tempdir().unwrap();
+        let mut file = File::create(dir.path().join("pyproject.toml")).unwrap();
+        writeln!(
+            file,
+            r#"
+[project]
+name = "example"
+
+[tool.rye]
+managed = true
+"#
+        )
+        .unwrap();
+
+        let runners = detect(dir.path());
+        assert_eq!(runners.len(), 1);
+        assert_eq!(runners[0].name, "rye");
+    }
+
     #[test]
     fn test_detect_poetry() {
         let dir = tempdir().unwrap();
@@ -239,6 +294,38 @@ serve = "example.server:run"
         );
     }
 
+    #[test]
+    fn test_python_validator_rye_scripts() {
+        let dir = tempdir().unwrap();
+        let mut file = File::create(dir.path().join("pyproject.toml")).unwrap();
+        writeln!(
+            file,
+            r#"
+[tool.rye]
+managed = true
+
+[tool.rye.scripts]
+build = "python build.py"
+dev = "python -m http.server"
+"#
+        )
+        .unwrap();
+
+        let validator = PythonValidator;
+        assert_eq!(
+            validator.supports_command(dir.path(), "build"),
+            CommandSupport::Supported
+        );
+        assert_eq!(
+            validator.supports_command(dir.path(), "dev"),
+            CommandSupport::Supported
+        );
+        assert_eq!(
+            validator.supports_command(dir.path(), "unknown"),
+            CommandSupport::Unknown
+        );
+    }
+
     #[test]
     fn test_python_validator_poetry_scripts() {
         let dir = tempdir().unwrap();