diff --git a/ingestion/README.md b/ingestion/README.md
index abd341f6..6e276000 100644
--- a/ingestion/README.md
+++ b/ingestion/README.md
@@ -16,6 +16,7 @@ The C-Elegans Utility CLI Tool supports the C-Elegans application by allowing us
     - [Ingesting Segmentations](#ingesting-segmentations)
       - [Extract segmentations from bitmap Files](#extract-segmentations-from-bitmap-files)
       - [Ingest the Segmentations](#ingest-the-segmentations)
+      - [Synapse coordinate conversion script](#synapse-coordinate-conversion-script)
   - [FAQ](#faq)
     - [What should be the file names and directory structure for the files I want to upload](#what-should-be-the-file-names-and-directory-structure-for-the-files-i-want-to-upload)
     - [Re-upload new version of the Dataset or related data](#re-upload-new-version-of-the-dataset-or-related-data)
@@ -145,7 +146,7 @@ When using the `add-dataset` subcommand, don't forget to specify the dataset ID
 The following flags help determine which files to upload:
 
 - `-seg`/`--segmentation`: Path to the directory or files containing neuron segmentation data.
-- `-3`/`--3d`: Path to the directory or files containing 3D neuron models.
+- `-3`/`--3d`: Path to the directory or files containing 3D neuron models and 3D synapse models.
 - `-e`/`--em`: Path to the directory or files containing EM tile images.
 - `-syn`/`--synapses`: Path to the directory or files containin synapses segmentation data.
 
@@ -157,6 +158,8 @@ For example, to upload 3D neuron models from `/path/to/3d/models` for the datase
 celegans ingest --data /path/to/data/db-raw-data add-dataset --id witvliet_2020_2 --3d /path/to/3d/models
 ```
 
+This command will also try to detect all the 3D synapse models that could be located under `/path/to/3d/models/synapses` and will also check for a conversion script if there is one. If the conversion script exists, the tool will automatically run it to convert the coordinates or data as required before uploading.
+
 You can upload multiple datasets by chaining `add-dataset` commands. For example, to upload 3D neuron models for `witvliet_2020_2` and EM images for `witvliet_2020_3`, use this command:
 
 ```bash
@@ -203,6 +206,24 @@ celegans ingest --data /path/to/data/db-raw-data add-dataset --id witvliet_2020_
 2. Using the correct flag for either neuron segmentations (`-seg` or `--segmentation`) or the synapses segmentations (`-syn` or `--synapses`)
 3. Pointing to the segmentation output directory, which is the same as the bitmap files directory.
 
+#### Synapse coordinate conversion script
+
+The synapse coordinate conversion script is searched in the 3D synapse model folder. It has to be named `convert.py` and has to contain at least one function named `convert` with this signature `convert(f: Path, mesh: trimesh.Geometry, bbox_center: ndarray) -> ndarray`.
+
+Here is an example of conversion script
+
+```python
+from pathlib import Path
+from numpy import ndarray
+import trimesh
+
+
+def convert(f: Path, mesh: trimesh.Geometry, bbox_center: ndarray) -> ndarray:
+   center = -bbox_center
+   center[0], center[1] = center[1] * 2, center[0] * 2
+   return center
+```
+
 ## FAQ
 
 ### What should be the file names and directory structure for the files I want to upload
@@ -234,6 +255,7 @@ Our suggestion would be to manage and store your files as follows:
 │   │   ├── ADEL.stl
 │   │   │   ...
 |   |   ├── synapses
+|   |   |   ├── convert.py  # [optional] coordinate script conversion
 |   |   |   ├── _0001_ADAL_synapses.ADAL_AVBL,AVBR,RIML_8414886-SEM_adult.stl  # or .obj
 |   |   |   ├── _0002_ADAL_synapses.ADAL_AVBL,AVJL,AVBR_8414874-SEM_adult.stl
 |   |   |   ├── ...
diff --git a/ingestion/ingestion/ingest.py b/ingestion/ingestion/ingest.py
index 31fbf7fb..207c84a2 100644
--- a/ingestion/ingestion/ingest.py
+++ b/ingestion/ingestion/ingest.py
@@ -363,6 +363,25 @@ def upload_3d(
         )
         import re
 
+        conversion_script = synapses_dirs[0] / "convert.py"
+
+        conversion_fun = None
+        if conversion_script.exists():
+            logger.info(f"Conversion script detected: {conversion_script}")
+            import importlib
+
+            spec = importlib.util.spec_from_file_location(  # type: ignore
+                "synapses_converter", conversion_script
+            )
+            module = importlib.util.module_from_spec(spec)  # type: ignore
+            spec.loader.exec_module(module)
+            try:
+                conversion_fun = getattr(module, "convert")
+            except AttributeError:
+                logger.warning(
+                    "Conversion script had been found, but it doesn't have a 'convert' function. Coordinate conversion will not be applied"
+                )
+
         synapses_positions_file = synapses_dirs[0] / "synapses_positions.txt"
         f = synapses_positions_file.open("w")
 
@@ -376,25 +395,15 @@ def extract_last_number(filename: str) -> str | None:
 
             mesh = trimesh.load(file)
 
-            if file.suffix == ".obj":
-                # Adapt the mesh position
-                # Step 1: negate the bbox
-                bbox_neg = -mesh.bounds
-
-                # Step 2: double x and y
-                bbox_neg[:, 0] *= 2  # double x
-                bbox_neg[:, 1] *= 2  # double y
-
-                # Step 3: swap x and y
-                bbox_swapped = bbox_neg.copy()
-                bbox_swapped[:, [0, 1]] = bbox_swapped[:, [1, 0]]
-            else:
-                bbox_swapped = mesh.bounds
-
             # Gets the center of the bbox
-            bbox_min, bbox_max = bbox_swapped
+            bbox = mesh.bounds
+            bbox_min, bbox_max = bbox
             center = (bbox_min + bbox_max) / 2
 
+            # We call the conversion function if there is one
+            if conversion_fun:
+                center = conversion_fun(file, mesh, center)
+
             # Extract catmaid connector id
             connector_id = extract_last_number(file.stem)
             entry = f"{connector_id}: [{center[0]}, {center[1]}, {center[2]}]\n"