diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml new file mode 100644 index 0000000..f563f7f --- /dev/null +++ b/.github/workflows/ci.yml @@ -0,0 +1,163 @@ +name: CI + +on: + push: + branches: + - main + - master + - develop + pull_request: + branches: + - main + - master + - develop + +# Minimal permissions for all jobs +permissions: + contents: read + +jobs: + # ----------------------------------------------------------------------- + # Python unit + integration tests + # ----------------------------------------------------------------------- + python-tests: + name: Python tests (pytest) + runs-on: ubuntu-latest + permissions: + contents: read + + steps: + - name: Checkout repository + uses: actions/checkout@v4 + + - name: Set up Python 3.11 + uses: actions/setup-python@v5 + with: + python-version: "3.11" + cache: "pip" + + - name: Install tdbsumstat and test dependencies + run: | + pip install -e . + pip install pytest pytest-cov + + - name: Run test suite + run: python -m pytest tests/ -v --tb=short + + # ----------------------------------------------------------------------- + # Nextflow stub tests (validate workflow DAG without running commands) + # ----------------------------------------------------------------------- + nextflow-stub-tests: + name: Nextflow stub tests + runs-on: ubuntu-latest + permissions: + contents: read + + steps: + - name: Checkout repository + uses: actions/checkout@v4 + + - name: Install Nextflow + uses: nf-core/setup-nextflow@v2 + with: + version: "latest-stable" + + - name: Stub test – ingestion + run: | + nextflow run main.nf -profile test_ingest -stub -ansi-log false + echo "✓ Ingestion stub test passed" + + - name: Stub test – export SNP + run: | + nextflow run main.nf -profile test_export_snp -stub -ansi-log false + echo "✓ Export SNP stub test passed" + + - name: Stub test – export locusbreaker + run: | + nextflow run main.nf -profile test_export_lb -stub -ansi-log false + echo "✓ Export locusbreaker stub test passed" + + - name: Stub test – export traits + run: | + nextflow run main.nf -profile test_export_traits -stub -ansi-log false + echo "✓ Export traits stub test passed" + + - name: Stub test – export regions + run: | + nextflow run main.nf -profile test_export_regions -stub -ansi-log false + echo "✓ Export regions stub test passed" + + - name: Stub test – recompute metadata + run: | + nextflow run main.nf -profile test_recompute_meta -stub -ansi-log false + echo "✓ Recompute metadata stub test passed" + + # ----------------------------------------------------------------------- + # Full Nextflow integration test (runs tdbsumstat commands via local Python) + # ----------------------------------------------------------------------- + nextflow-integration-test: + name: Nextflow integration test (ingest + export) + runs-on: ubuntu-latest + permissions: + contents: read + + steps: + - name: Checkout repository + uses: actions/checkout@v4 + + - name: Set up Python 3.11 + uses: actions/setup-python@v5 + with: + python-version: "3.11" + cache: "pip" + + - name: Install tdbsumstat + run: pip install -e . + + - name: Install Nextflow + uses: nf-core/setup-nextflow@v2 + with: + version: "latest-stable" + + - name: Create CI data table with absolute file paths + run: | + { + echo "FILE,CELL,GENE,PHENO_VAR,N" + echo "$(pwd)/example_data/dummy_out_ENSG0000010000.tsv.gz,Tgd,ENSG0000010000,1.5,4000" + echo "$(pwd)/example_data/dummy_out_ENSG0000010001.tsv.gz,Tgd,ENSG0000010001,1.5,4000" + } > /tmp/example_data_table_ci.csv + + - name: Run ingestion pipeline (local, no container) + run: | + nextflow run main.nf \ + --ingestion true \ + --file_path_ingestion /tmp/example_data_table_ci.csv \ + --mapping_file "$(pwd)/example_data/mapping_file_test.csv" \ + --type_sumstat qtl \ + --tiledb_name test_ci \ + --ingestion_chunk_files 2 \ + --maf 0 \ + --mac 0 \ + --outdir ./results_ci \ + -process.container null \ + -ansi-log false + + - name: Verify TileDB was created + run: | + ls -la results_ci/TileDB/TileDB_test_ci/ + echo "✓ TileDB created successfully" + + - name: Run SNP export (local, no container) + run: | + nextflow run main.nf \ + --export true \ + --snp "$(pwd)/example_data/snp_list_sc.csv" \ + --tiledb_path "$(pwd)/results_ci/TileDB/TileDB_test_ci" \ + --uri_path "$(pwd)/results_ci/TileDB/TileDB_test_ci" \ + --attrs "SE,BETA" \ + --out out_ci \ + --type_sumstat qtl \ + --outdir ./results_ci \ + -process.container null \ + -ansi-log false + echo "✓ SNP export completed" diff --git a/README.md b/README.md index b983916..9ee03a0 100755 --- a/README.md +++ b/README.md @@ -40,5 +40,175 @@ If you are running the pipeline with nextflow change the path where the conda en #### To check how to use the Nextflow pipeline for extracting and ingesting data please refer here [HERE](https://github.com/HTGenomeAnalysisUnit/TileDB-sumstat/blob/nextflow_branch/docs/README.md) +--- + +### Code structure + +The Python package lives under `tdbsumstat/` and is organised as follows: + +``` +tdbsumstat/ +├── main.py # CLI entry-point (registers ingest + export commands) +├── cli/ +│ ├── ingestion.py # `tdbsumstat ingest` CLI command +│ └── export/ # `tdbsumstat export` CLI command (package) +│ ├── __init__.py # re-exports the `export` command +│ ├── command.py # CLI decorator + routing to handlers +│ ├── helpers.py # shared TileDB open/metadata helper +│ ├── snp.py # export by SNP list +│ ├── regions.py # export by genomic regions +│ ├── locusbreaker.py # locusbreaker wrapper +│ ├── metadata.py # metadata export / recompute +│ └── traits.py # bulk trait export +└── utils/ + ├── __init__.py # acat_optimized, compute_pheno_variance, z_to_p_via_chi2 + ├── harmonize_ingest.py # backward-compat shim → re-exports from utils/ingest/ + ├── ingest/ # ingestion pipeline (package) + │ ├── __init__.py # Harmonize class + HarmonizationError + │ ├── errors.py # HarmonizationError exception + │ ├── schema.py # SchemaMixin – TileDB array creation + │ ├── mapping.py # MappingMixin – column-mapping CSV parsing + │ ├── harmonize.py # HarmonizeMixin – data normalisation + │ ├── qc.py # QCMixin – optional gwaslab QC + │ ├── writer.py # WriterMixin – TileDB data writer + │ └── metadata.py # MetadataMixin – metadata management + ├── locusbreaker.py # pandas-based locusbreaker (legacy) + ├── locusbreaker_plpl.py # Polars-based locusbreaker (used by export) + └── update_metadata.py # standalone metadata update utility +scripts/ + ├── create_metadata.py # one-off metadata creation helper + ├── fix_json.py # one-off JSON repair helper + └── generate_table_cell_sumstat.py # one-off table generation helper +``` + +#### Ingestion pipeline in detail + +The `Harmonize` class (in `tdbsumstat/utils/ingest/`) is composed from focused mixin classes: + +| Module | Mixin | Responsibility | +|--------|-------|----------------| +| `schema.py` | `SchemaMixin` | Create the TileDB sparse array schema | +| `mapping.py` | `MappingMixin` | Parse the column-mapping CSV | +| `harmonize.py` | `HarmonizeMixin` | Rename columns, handle alleles, compute p-values | +| `qc.py` | `QCMixin` | Optional gwaslab-based QC checks | +| `writer.py` | `WriterMixin` | Deduplicate and append data to TileDB | +| `metadata.py` | `MetadataMixin` | Create, merge and export metadata JSON/CSV | + +A typical ingestion workflow (Python API): + +```python +from tdbsumstat.utils.ingest import Harmonize +import polars as pl + +h = Harmonize( + mapping_file="mapping.csv", + uri="my_tiledb", + type_sumstat="qtl", # or "gwas" + pvar_file=None, + type_trait="quant", # or "binary" + mac=None, + maf=None, + permuted=False, +) + +# One-time setup +h.create_tiledb() +h.create_mapping() + +# Per-file loop +for filepath, cell, gene in file_list: + sumstat = pl.read_csv(filepath, separator="\t", null_values="NA") + h.harmonize(sumstat=sumstat, cell=cell, gene=gene, n=n, pheno_var=pheno_var) + h.ingest_data(file_path=filepath) + h.create_metadata(file_path=filepath) + +# Finalise metadata +h.merge_metadata_files() +``` + +--- + +### Running tests + +Tests live in the `tests/` directory and use [pytest](https://pytest.org). + +```bash +# Install dev dependencies +pip install pytest pytest-cov + +# Run the full test suite +python -m pytest tests/ -v + +# Run only ingestion tests +python -m pytest tests/test_ingest.py -v + +# Run only export tests +python -m pytest tests/test_export.py -v + +# Run with coverage report +python -m pytest tests/ --cov=tdbsumstat --cov-report=term-missing +``` + +Test files: + +| File | What it tests | +|------|---------------| +| `tests/test_utils.py` | `acat_optimized`, `compute_pheno_variance`, `z_to_p_via_chi2` | +| `tests/test_harmonize.py` | `Harmonize` class (legacy + backward-compat) | +| `tests/test_ingest.py` | Each ingest mixin + end-to-end pipeline with example data | +| `tests/test_export.py` | All export modules + CLI command routing | + +--- +### Testing the Nextflow pipeline + +#### Stub tests (no data required) + +Every Nextflow module has a `stub` block that creates placeholder output files +instead of running the actual `tdbsumstat` commands. Stub tests validate the +workflow DAG structure (channels, process I/O, publish dirs) without needing +containers or real data. + +```bash +# Install Nextflow first: https://www.nextflow.io/docs/latest/install.html + +nextflow run main.nf -profile test_ingest -stub # ingestion DAG +nextflow run main.nf -profile test_export_snp -stub # SNP export DAG +nextflow run main.nf -profile test_export_regions -stub # region export DAG +nextflow run main.nf -profile test_export_traits -stub # trait export DAG +nextflow run main.nf -profile test_export_lb -stub # locusbreaker DAG +nextflow run main.nf -profile test_recompute_meta -stub # recompute metadata DAG +``` + +These stub tests are run automatically on every push and pull request via +[`.github/workflows/ci.yml`](.github/workflows/ci.yml). + +#### Full integration test (local Python + Nextflow) + +```bash +# 1. Install tdbsumstat +pip install -e . + +# 2. Build a data table with absolute paths +{ + echo "FILE,CELL,GENE,PHENO_VAR,N" + echo "$(pwd)/example_data/dummy_out_ENSG0000010000.tsv.gz,Tgd,ENSG0000010000,1.5,4000" + echo "$(pwd)/example_data/dummy_out_ENSG0000010001.tsv.gz,Tgd,ENSG0000010001,1.5,4000" +} > /tmp/example_data_table_ci.csv + +# 3. Run ingestion (uses local Python – no container needed) +nextflow run main.nf \ + --ingestion true \ + --file_path_ingestion /tmp/example_data_table_ci.csv \ + --mapping_file "$(pwd)/example_data/mapping_file_test.csv" \ + --type_sumstat qtl \ + --tiledb_name test_ci \ + --ingestion_chunk_files 2 \ + --maf 0 --mac 0 \ + --outdir ./results_ci \ + -process.container null \ + -ansi-log false +``` + +See [`docs/README.md`](docs/README.md) for the full Nextflow parameter reference. diff --git a/conf/local.config b/conf/local.config new file mode 100644 index 0000000..dfa2bf7 --- /dev/null +++ b/conf/local.config @@ -0,0 +1,6 @@ +process { + withLabel: 'process_high' { + memory = 12.GB // or 8.GB; stay under your ~16 GB machine RAM + cpus = 4 + } +} diff --git a/conf/test.config b/conf/test.config index 272edb2..3caa0ae 100644 --- a/conf/test.config +++ b/conf/test.config @@ -2,25 +2,24 @@ profiles { test_ingest { params { - ingest = true + ingest = true + ingestion = true file_path_ingestion = "${projectDir}/example_data/example_data_table.csv" mapping_file = "${projectDir}/example_data/mapping_file_test.csv" - ingestion = true type_sumstat = "qtl" qc = false ingestion_chunk_files = 2 tiledb_name = "test" - outdir = "./results" // Add this missing parameter - publish_dir_mode = 'copy' // Add this missing parameter + outdir = "./results" + publish_dir_mode = 'copy' } } test_export_lb { params { - export = true - //uri_path = "/lustre/scratch124/humgen/projects_v2/cardinal_analysis/analysis/core_dataset/freeze3/tiledbs/Tensor/TileDB_metanalyses_gh_celltype2_freeze3" - uri_path = "${projectDir}/example_data/TileDB_test" + export = true locusbreaker = true + uri_path = "${projectDir}/example_data/TileDB_test" out = "out_test" type_sumstat = "qtl" hole_lb = 250000 @@ -28,72 +27,76 @@ profiles { maf_lb = 0.001 locus_max_size_lb = 3000000 cis_trans_lb = "cis" - table_lb = "${projectDir}/example_data/locusbreaker_test_table_sc.csv" - batch_name = 1 - outdir = "./results" // Add this missing parameter - publish_dir_mode = 'copy' // Add this missing parameter + table_lb = "${projectDir}/example_data/locusbreaker_test_table_sc.csv" + outdir = "./results" + publish_dir_mode = 'copy' } } + test_export_snp { params { - export = true - uri_path = "${projectDir}/example_data/TileDB_test" + export = true snp = "${projectDir}/example_data/snp_list_sc.csv" + tiledb_path = "${projectDir}/example_data/TileDB_test" + uri_path = "${projectDir}/example_data/TileDB_test" attrs = "SE,BETA" out = "out" type_sumstat = "qtl" - outdir = "./results" // Add this missing parameter - publish_dir_mode = 'copy' // Add this missing parameter + outdir = "./results" + publish_dir_mode = 'copy' } } + test_export_regions { params { - export = true - uri_path = "${projectDir}/example_data/TileDB_test" + export = true regions = "${projectDir}/example_data/region_list_sc.csv" + uri_path = "${projectDir}/example_data/TileDB_test" attrs = "SE,BETA" out = "out" type_sumstat = "qtl" - outdir = "./results" // Add this missing parameter - publish_dir_mode = 'copy' // Add this missing parameter + tiledb_batch_size = 1 + outdir = "./results" + publish_dir_mode = 'copy' } } + test_export_traits { params { - export = true + export = true export_traits = true uri_path = "${projectDir}/example_data/TileDB_test" - list_traits = "${projectDir}/example_data/trait_list.csv" + list_traits = "${projectDir}/example_data/trait_list_test.csv" out = "out" type_sumstat = "qtl" - outdir = "./results" // Add this missing parameter - publish_dir_mode = 'copy' // Add this missing parameter + outdir = "./results" + publish_dir_mode = 'copy' tiledb_batch_size = 1 } } + test_export_meta { params { - export = true + export = true export_meta = true uri_path = "${projectDir}/example_data/TileDB_test" - list_traits = "${projectDir}/example_data/trait_list.csv" out = "out" type_sumstat = "qtl" - outdir = "./results" // Add this missing parameter - publish_dir_mode = 'copy' // Add this missing parameter - tiledb_batch_size = 100 + outdir = "./results" + publish_dir_mode = 'copy' } } + test_recompute_meta { params { - recompute_meta = true - uri_path = "/project/cardinal/QTLs/freeze3/TileDBs/gh_metanalyses/TileDB_metanalyses_gh_celltype2_freeze3" - list_traits = "${projectDir}/gh_meta.csv" - mac =10 + recompute_meta = true + uri_path = "${projectDir}/example_data/TileDB_test" + list_traits = "${projectDir}/example_data/recompute_meta_test_table.csv" + mac = 10 out = "out" type_sumstat = "qtl" - outdir = "./results" // Add this missing parameter - publish_dir_mode = 'copy' // Add this missing parameter + outdir = "./results" + publish_dir_mode = 'copy' tiledb_batch_size = 10 } } diff --git a/docs/README.md b/docs/README.md index 0f88c9b..2d1e0b6 100755 --- a/docs/README.md +++ b/docs/README.md @@ -4,16 +4,29 @@ TileDB-sumstat is a Nextflow + Python toolkit for scalable ingestion and export ## Table of Contents -- [Requirements](#requirements) -- [Pipeline Overview](#pipeline-overview) -- [Usage with Nextflow](#usage-with-nextflow) - - [Ingestion](#ingestion) - - [Export](#export) - - [SNP-based Export](#snp-based-export) - - [Region-based Export](#region-based-export) - - [Locusbreaker](#locusbreaker) -- [Test Data](#test-data) -- [Support and Contribution](#support-and-contribution) +- [TileDB-sumstat](#tiledb-sumstat) + - [Table of Contents](#table-of-contents) + - [Requirements](#requirements) + - [Pipeline Overview](#pipeline-overview) + - [Usage with Nextflow](#usage-with-nextflow) + - [Ingestion](#ingestion) + - [Required Files](#required-files) + - [Parameters](#parameters) + - [Example](#example) + - [Export](#export) + - [Common Parameters](#common-parameters) + - [SNP-based Export](#snp-based-export) + - [Region-based Export](#region-based-export) + - [Traits Export](#traits-export) + - [Locusbreaker](#locusbreaker) + - [Metadata Export](#metadata-export) + - [Recompute Metadata](#recompute-metadata) + - [Nextflow Modules](#nextflow-modules) + - [Testing the Nextflow Pipeline](#testing-the-nextflow-pipeline) + - [Stub Tests (CI / no data required)](#stub-tests-ci--no-data-required) + - [Integration Test](#integration-test) + - [Test Data](#test-data) + - [Support and Contribution](#support-and-contribution) --- @@ -41,7 +54,7 @@ TileDB-sumstat implements two main workflows executed in separate steps: 2. **Export** — Query the TileDB array and export results by: - SNP - Genomic region - - Entire summary statistics + - Entire summary statistics (trait-based) - Clumping using the "Locusbreaker" algorithm The program can be used with Nextflow or as standalone Python utilities. @@ -58,36 +71,48 @@ Import summary statistics files into a TileDB array. #### Required Files -- **Mapping File** (.csv): Maps input GWAS columns to standard TileDB-sumstat columns. See `example_data/mapping_file_test` for format. First column: original GWAS names, second column: converted names. -- **Data Table**: Lists files to ingest. See `example_data/example_data_table.csv`. Must include: - - Path to GWAS files - - Optional: Additional columns can be added to this file if they are not present in the summary statistics: - - `N`: Sample size for specific summary statistics - - `N_CASES`: Sample size for cases specific to a summary statistics - - `N_CONTROLS`: Sample size for controls specific to a summary statistics - - `CELL`: Cell name for single QTL studies - - `GENE`: GENE name for single QTL studies - - `PHENO_VAR`: Phenotypic variance for the specific trait (only for QTLs single cell) - - `TRAIT`: Trait name for GWAS studies +- **Mapping File** (.csv): Maps input GWAS columns to standard TileDB-sumstat columns. See `example_data/mapping_file_test.csv` for format. First column: original GWAS names, second column: converted names. +- **Data Table** (`example_data/example_data_table.csv`): Lists files to ingest. Must contain **absolute file paths** in the `FILE` column. Optional columns: + - `N`: Sample size + - `N_CASES` / `N_CONTROLS`: Case/control sizes for binary GWAS + - `CELL`: Cell type (single-cell QTL) + - `GENE`: Gene name (single-cell QTL) + - `PHENO_VAR`: Phenotypic variance (single-cell QTL) + - `TRAIT`: Trait name (GWAS) + +> **Note on file paths:** The `FILE` column in the data table must contain absolute paths that are accessible from the compute nodes running the pipeline. The file `example_data/example_data_table_test.csv` shows the column format; for production runs, replace the paths with absolute paths on your cluster. #### Parameters **Required:** -- `--ingest` (flag to enable ingestion) +- `--ingestion` (flag to enable ingestion) - `--file_path_ingestion` (path to data table file) +- `--mapping_file` (path to column mapping file) - `--type_sumstat` (either `gwas` or `qtl`) +- `--tiledb_name` (name for the TileDB array) **Optional:** -- `--qc` (enable QC processing) -- `--ingestion_chunk_files` (number of files to ingest simultaneously, default: 4) +- `--qc` (enable QC processing via gwaslab) +- `--ingestion_chunk_files` (number of files to ingest per batch, default: 4) +- `--maf` (minimum allele frequency filter, default: 0) +- `--mac` (minimum allele count filter, default: 0) +- `--permuted` (compute SE from permuted p-value) +- `--pvar_file` (pvar file to align alleles) +- `--outdir` (output directory, default: `./results`) #### Example ```bash -nextflow run main.nf -profile singularity --ingest --file_path_ingestion example_data/example_data_table.csv --mapping_file example_data/mapping_file_test.csv --type_sumstat qtl --ingestion_chunk_files 4 +nextflow run main.nf \ + -profile singularity \ + --ingestion \ + --file_path_ingestion example_data/example_data_table.csv \ + --mapping_file example_data/mapping_file_test.csv \ + --type_sumstat qtl \ + --tiledb_name my_tiledb \ + --ingestion_chunk_files 4 ``` -Using Nextflow profile you can also use - +Using a pre-defined test profile: ```bash nextflow run main.nf -profile test_ingest,singularity ``` @@ -99,85 +124,246 @@ Query and export data from the TileDB array. #### Common Parameters -**Required:**: -- --export (flag to enable export) -- --tiledb_path (path to TileDB array) -- --out (output file prefix) -- --type_sumstat (type of summary statistics, either gwas or qtl for single cell) +**Required:** +- `--export` (flag to enable export) +- `--uri_path` (path to TileDB array) +- `--out` (output file prefix) +- `--type_sumstat` (type of summary statistics: `gwas` or `qtl`) -**Optional**: -- --attrs (attributes to export, e.g., "BETA,SE,PVAL,EAF,A1,A2") +**Optional:** +- `--attrs` (attributes to export, e.g., `"BETA,SE,EAF"`, default: `"P,SNPID,EAF,BETA,SE"`) #### SNP-based Export Extract specific SNP positions. -**Required** -- --snp (path to SNP list file) +**Required:** +- `--snp` (path to SNP list CSV, columns: `CHR`, `POS`, `TRAIT`) + +Example files: `example_data/snp_list_sc.csv` -Example Files: -- GWAS: example_data/snp_list_gwas.csv -- Single-cell: example_data/snp_list_sc.csv +```bash +nextflow run main.nf \ + -profile singularity \ + --export \ + --snp example_data/snp_list_sc.csv \ + --tiledb_path /path/to/tiledb \ + --uri_path /path/to/tiledb \ + --attrs "BETA,SE,P" \ + --out results/snp_output \ + --type_sumstat qtl +``` -#### Example: +Quick test (stub – no data needed): ```bash -nextflow run main.nf -profile singularity --export --tiledb_path /path/to/tiledb --snp /path/to/snp_list.csv --attrs "BETA,SE,PVAL,EAF,A1,A2" --out /path/to/output_prefix --type_sumstat gwas +nextflow run main.nf -profile test_export_snp -stub ``` + #### Region-based Export -Extract genomic regions using BED format. +Extract genomic intervals. **Required:** -- --table-regions (path to regions file) +- `--regions` (path to regions CSV, columns: `CHR`, `START`, `END`, `TRAIT`) + +Example file: `example_data/region_list_sc.csv` -Example: ```bash -nextflow run main.nf -profile singularity --export --tiledb_path /path/to/tiledb --table-regions /path/to/regions_table.csv --attrs "BETA,SE,PVAL" --out /path/to/output_prefix --type_sumstat gwas +nextflow run main.nf \ + -profile singularity \ + --export \ + --regions example_data/region_list_sc.csv \ + --uri_path /path/to/tiledb \ + --attrs "BETA,SE,P" \ + --out results/regions_output \ + --type_sumstat qtl ``` -Quick Test: +Quick test: ```bash -nextflow run main.nf -profile test_export_lb,singularity +nextflow run main.nf -profile test_export_regions -stub +``` + +#### Traits Export + +Export complete summary statistics for a list of traits or cell-type/gene combinations. + +**Required:** +- `--export_traits` (flag) +- `--list_traits` (path to CSV with `TRAIT` column; for QTL: `CELL:GENE` format) + +Example file: `example_data/trait_list_test.csv` + +```bash +nextflow run main.nf \ + -profile singularity \ + --export \ + --export_traits \ + --list_traits example_data/trait_list_test.csv \ + --uri_path /path/to/tiledb \ + --out results/traits_output \ + --type_sumstat qtl +``` + +Quick test: +```bash +nextflow run main.nf -profile test_export_traits -stub ``` #### Locusbreaker -Identify genomic loci with significant associations and export locus-centric results. +Identify genomic loci with significant associations. + +**Required:** +- `--locusbreaker` (flag) +- `--table_lb` (path to traits table, columns: `CHR`, `TRAIT`, `SIG`, `LIM`) + +**Optional:** +- `--maf_lb` (MAF filter, default: 0.001) +- `--locus_max_size_lb` (maximum locus size in bp, default: 3 Mb) +- `--hole_lb` (maximum gap within loci in bp, default: 250 kb) +- `--cis_trans_lb` (for QTLs: `cis` or `trans`, default: `cis`) + +Example: +```bash +nextflow run main.nf \ + -profile singularity \ + --locusbreaker \ + --table_lb example_data/locusbreaker_test_table_sc.csv \ + --uri_path /path/to/tiledb \ + --out results/lb_output \ + --type_sumstat qtl +``` + +Quick test: +```bash +nextflow run main.nf -profile test_export_lb -stub +``` + +#### Metadata Export + +Export the merged metadata stored in the TileDB array to CSV. + +```bash +tdbsumstat export --export-meta --uri-path /path/to/tiledb --type-sumstat qtl --out metadata_out +``` + +#### Recompute Metadata + +Recompute per-trait/cell metadata statistics after applying a MAC filter without modifying the TileDB data. **Required:** -- --table-lb (path to traits table, see example_data/locusbreaker_test_table.csv) +- `--recompute_meta` (flag) +- `--list_traits` (CSV with `CELL` and `CHR` columns for QTL, or `TRAIT` and `CHR` for GWAS) +- `--uri_path` +- `--mac` (minimum allele count threshold) + +Example file: `example_data/recompute_meta_test_table.csv` -**Optional** -- --maf-lb (minor allele frequency filter) -- --locus-max-size (maximum locus size in base pairs) -- --hole-lb (maximum gap size within loci in base pairs) -- --cis-trans (for QTLs: filter by cis or trans) +```bash +nextflow run main.nf \ + -profile singularity \ + --recompute_meta \ + --list_traits example_data/recompute_meta_test_table.csv \ + --uri_path /path/to/tiledb \ + --mac 10 \ + --out results/meta_out \ + --type_sumstat qtl +``` -Locusbreaker Algorithm: -1. Select SNPs below p-value threshold (suggested: 1e-6) -2. Group consecutive SNPs within distance threshold (suggested: 250 kb) -3. Retain groups containing at least one genome-wide significant SNP (suggested: 5e-8) -4. Expand locus boundaries by margin (e.g., +100 kb) -5. Apply additional filters (MAF, locus size, cis/trans) +Quick test: +```bash +nextflow run main.nf -profile test_recompute_meta -stub +``` --- -#### Metadata extraction +## Nextflow Modules + +The pipeline is composed of the following Nextflow process modules under `modules/`: + +| Module | Process | Description | +|--------|---------|-------------| +| `create_tiledb/` | `CREATE_TILEDB` | Creates the TileDB sparse array schema | +| `ingestion/` | `INGEST_DATA` | Harmonises and ingests one file-list chunk into TileDB | +| `merge_metadata/` | `MERGE_METADATA` | Collects per-chunk metadata JSON files and stores merged metadata in TileDB | +| `snp/` | `EXPORT_SNP` | Exports data for a list of SNP positions | +| `regions/` | `EXPORT_REGIONS` | Exports data for a list of genomic intervals | +| `traits/` | `TRAITS` | Exports complete summary statistics for a list of traits | +| `locusbreaker/` | `EXPORT_LOCUSBREAKER` | Runs the Locusbreaker algorithm and exports locus/segment tables | +| `recompute_meta/` | `RECOMPUTE_META` | Recomputes metadata with a MAC filter | -Metadata are structured as json in tiledb. To extract them you can use the following command: +Each module has a `stub` block so the workflow DAG can be validated without executing the actual commands (see [Testing](#testing-the-nextflow-pipeline)). + +--- + +## Testing the Nextflow Pipeline + +### Stub Tests (CI / no data required) + +Stub tests validate the workflow DAG structure (channels, processes, outputs) without running the actual `tdbsumstat` commands. They are the recommended way to test the pipeline in CI or when data is not available. + +All test profiles are defined in `conf/test.config` and registered in `nextflow.config`. ```bash -tdbsumstat export metadata +# Validate ingestion workflow +nextflow run main.nf -profile test_ingest -stub + +# Validate export workflows +nextflow run main.nf -profile test_export_snp -stub +nextflow run main.nf -profile test_export_regions -stub +nextflow run main.nf -profile test_export_traits -stub +nextflow run main.nf -profile test_export_lb -stub +nextflow run main.nf -profile test_recompute_meta -stub ``` -tiledb_meta -{'traits': [], 'CELL': ['Tgd'], 'Tgd': {'20': {'ENSG0000010000': {'ACAT': 0.0, 'N': 4000.0, 'PHENO_VAR': 1.0}, 'ENSG0000010001': {'ACAT': 0.0, 'N': 4000.0, 'PHENO_VAR': 1.0}}}} +These stubs are also run automatically on every push and pull request via the [CI workflow](.github/workflows/ci.yml). + +### Integration Test + +To run a full integration test that actually executes the ingestion and export commands, you need: +1. `tdbsumstat` installed (`pip install -e .`) +2. Nextflow installed + +```bash +# Build a CI-friendly data table with absolute paths +{ + echo "FILE,CELL,GENE,PHENO_VAR,N" + echo "$(pwd)/example_data/dummy_out_ENSG0000010000.tsv.gz,Tgd,ENSG0000010000,1.5,4000" + echo "$(pwd)/example_data/dummy_out_ENSG0000010001.tsv.gz,Tgd,ENSG0000010001,1.5,4000" +} > example_data/example_data_table_ci.csv + +# Run ingestion (no container – uses local tdbsumstat) +nextflow run main.nf \ + --ingestion true \ + --file_path_ingestion example_data/example_data_table_ci.csv \ + --mapping_file /example_data/mapping_file_test.csv \ + --type_sumstat qtl \ + --tiledb_name test_ci \ + --ingestion_chunk_files 2 \ + --maf 0 \ + --mac 0 \ + --outdir ./results_ci \ + -process.container null \ + -ansi-log false +``` + +--- + ## Test Data -- example_data/snp_list.csv - Example SNP list for SNP-based export -- example_data/example_data_table.csv - Example table for regions and ingestion -- example_data/mapping_file_test - Example mapping file for ingestion -- example_data/locusbreaker_test_table.csv - Example table for Locusbreaker +| File | Description | +|------|-------------| +| `example_data/dummy_out_ENSG0000010000.tsv.gz` | Example QTL summary statistics (gene ENSG0000010000) | +| `example_data/dummy_out_ENSG0000010001.tsv.gz` | Example QTL summary statistics (gene ENSG0000010001) | +| `example_data/example_data_table.csv` | Ingestion data table (absolute paths, for cluster use) | +| `example_data/example_data_table_test.csv` | Ingestion data table (filenames only, documents column format) | +| `example_data/mapping_file_test.csv` | Column mapping file for example data | +| `example_data/snp_list_sc.csv` | SNP list for SNP-based export tests | +| `example_data/region_list_sc.csv` | Region list for region-based export tests | +| `example_data/locusbreaker_test_table_sc.csv` | Traits table for Locusbreaker tests | +| `example_data/trait_list_test.csv` | Trait list (`TRAIT` column) for traits export tests | +| `example_data/recompute_meta_test_table.csv` | Cell/CHR table for recompute metadata tests | --- @@ -190,5 +376,3 @@ Contributions are welcome! Please: 2. Create a feature branch 3. Submit a pull request against the main branch 4. Follow the repository's contribution guidelines - ---- \ No newline at end of file diff --git a/example_data/dummy_out_ENSG0000010000.tsv b/example_data/dummy_out_ENSG0000010000.tsv new file mode 100644 index 0000000..c7d4b8e --- /dev/null +++ b/example_data/dummy_out_ENSG0000010000.tsv @@ -0,0 +1,2001 @@ +Chr Gene cell.type pos a0 a1 SNP START EAF p beta se +20 ENSG0000010000 Tgd 1825 A C chr20:1825:A:C -243213 0.22321073814882275 0.7364712141640124 0.3533989748458226 0.8922873881371406 +20 ENSG0000010000 Tgd 1425 G A chr20:1425:G:A -468756 0.09369523986159245 0.2326608933907396 0.20403745809996066 0.5616838178756743 +20 ENSG0000010000 Tgd 8929 G T chr20:8929:G:T -28971 0.5892656838759087 0.8094304566778266 -0.987002480643878 0.8060134325809751 +20 ENSG0000010000 Tgd 6925 C A chr20:6925:C:A -402749 0.3799273006373374 0.3589793804846284 -0.3120885550420578 0.26525634635479106 +20 ENSG0000010000 Tgd 712 G A chr20:712:G:A 467096 0.3785343772083535 0.552040631273227 0.6588093285059897 0.6189012326118818 +20 ENSG0000010000 Tgd 5926 T A chr20:5926:T:A -451950 0.6612633185677101 0.7730683407886919 0.9704430413215155 0.8554624032941318 +20 ENSG0000010000 Tgd 1655 G C chr20:1655:G:C -24565 0.6356844442644002 0.36483217897008424 -0.2596380657662347 0.2102975237407162 +20 ENSG0000010000 Tgd 4375 A T chr20:4375:A:T 60086 0.7291267979503492 0.1634024937619284 -0.24108911648470444 0.9895338272859586 +20 ENSG0000010000 Tgd 9126 T C chr20:9126:T:C 383794 0.7683135775923722 0.05593794754928394 0.6436051880136167 0.8052407549704431 +20 ENSG0000010000 Tgd 6573 C A chr20:6573:C:A -278769 0.913136124185545 0.5671800514785023 0.4358285414379519 0.21341391751008648 +20 ENSG0000010000 Tgd 8180 T C chr20:8180:T:C -353587 0.24662750769398345 0.5613681341631508 -0.47451678295412947 0.5850014042333169 +20 ENSG0000010000 Tgd 9561 G C chr20:9561:G:C -270026 0.997325777989161 0.13833174489085587 -0.012968330220737956 0.7560263753762041 +20 ENSG0000010000 Tgd 1797 G A chr20:1797:G:A -96543 0.38161928650653676 0.9961213802400968 0.058228690198274036 0.9711072992360046 +20 ENSG0000010000 Tgd 189 A C chr20:189:A:C 305934 0.6409617985798081 0.11155217359587644 -0.13046949866179003 0.4542699826228772 +20 ENSG0000010000 Tgd 4316 T A chr20:4316:T:A 412804 0.6253001935664175 0.8416693481724671 0.015325763955268412 0.1997121906629683 +20 ENSG0000010000 Tgd 6127 T A chr20:6127:T:A 128038 0.3241560570046731 0.019476742385832302 0.8581972325292342 0.878843155945361 +20 ENSG0000010000 Tgd 5039 T A chr20:5039:T:A -247428 0.8780095992040405 0.9469494452979941 -0.8286930958642424 0.4865044728532972 +20 ENSG0000010000 Tgd 1134 G T chr20:1134:G:T -222068 0.527673787418254 0.6065939174826289 0.9287258120149104 0.9289845795091747 +20 ENSG0000010000 Tgd 3296 C G chr20:3296:C:G 204314 0.6498780576394535 0.43810008391450406 0.035151682071181245 0.12188319167239746 +20 ENSG0000010000 Tgd 3682 A C chr20:3682:A:C -477944 0.5883087184572333 0.230114732596577 -0.559565231096881 0.0719220929230235 +20 ENSG0000010000 Tgd 965 T A chr20:965:T:A 449401 0.031412958053018136 0.3304284890804987 0.028312239617178214 0.2791987867005824 +20 ENSG0000010000 Tgd 7954 G T chr20:7954:G:T 322733 0.4729729429445937 0.4070599614859366 -0.8113484070162356 0.6593237667651484 +20 ENSG0000010000 Tgd 5805 G A chr20:5805:G:A 206073 0.6534554882657916 0.6461797512949844 -0.8787746518459727 0.7284853748527415 +20 ENSG0000010000 Tgd 1791 T G chr20:1791:T:G -353009 0.4218816398344042 0.27854514466694047 -0.500387104235799 0.9233423336767368 +20 ENSG0000010000 Tgd 7261 G T chr20:7261:G:T 406651 0.4010402925494526 0.058635399972178925 -0.2420537620461678 0.9853235349359463 +20 ENSG0000010000 Tgd 4346 G C chr20:4346:G:C -56445 0.6965915036001625 0.730505317415466 0.5667230569685744 0.6622094406387945 +20 ENSG0000010000 Tgd 7974 C T chr20:7974:C:T -438676 0.5791802908162562 0.5421952013742742 0.4959511207581282 0.05810810763457559 +20 ENSG0000010000 Tgd 9572 G T chr20:9572:G:T -440358 0.9607789032744504 0.08011146524058688 -0.6283500780385536 0.5954400713435777 +20 ENSG0000010000 Tgd 3854 G A chr20:3854:G:A 487335 0.8902873141294375 0.24621534778862486 0.1890383070668824 0.619762128821771 +20 ENSG0000010000 Tgd 6869 T C chr20:6869:T:C -249720 0.2656145125313538 0.13087828212745645 0.291001577675299 0.45776734799788155 +20 ENSG0000010000 Tgd 1189 A G chr20:1189:A:G 151332 0.9984544408544423 0.9960964478550944 -0.853478557800734 0.21394115795477336 +20 ENSG0000010000 Tgd 4346 T C chr20:4346:T:C 423653 0.06879131406001926 0.24428441650813137 -0.43002521756668655 0.43874638843470215 +20 ENSG0000010000 Tgd 8901 C A chr20:8901:C:A 200305 0.8171041351154616 0.2993787521999779 0.32677742993215464 0.9389910739231768 +20 ENSG0000010000 Tgd 2201 C A chr20:2201:C:A 432931 0.10703597770941764 0.5532236408848159 -0.45530357537036736 0.6052249972031937 +20 ENSG0000010000 Tgd 5618 T C chr20:5618:T:C 29959 0.48853185214937656 0.9053364910793232 0.6922074265897109 0.09320616924502069 +20 ENSG0000010000 Tgd 6940 C A chr20:6940:C:A -496283 0.33355653860508816 0.13081966070170226 0.9595959076576719 0.16242039429761226 +20 ENSG0000010000 Tgd 7240 G A chr20:7240:G:A -382692 0.07524386007376704 0.883106393300143 0.8078571431197863 0.5460446989163168 +20 ENSG0000010000 Tgd 6050 T G chr20:6050:T:G -366364 0.04182885816885784 0.36465151532725604 0.8661760210413083 0.9722240687522432 +20 ENSG0000010000 Tgd 654 C T chr20:654:C:T 215198 0.24952973922292443 0.10279362167178563 0.5602324837428854 0.8842505667495579 +20 ENSG0000010000 Tgd 6659 G A chr20:6659:G:A -311927 0.7365644717550821 0.33218546794642867 0.8616317720966511 0.8024329037982018 +20 ENSG0000010000 Tgd 4066 C T chr20:4066:C:T 325622 0.7012781881399126 0.3825417225969343 -0.9225507846684271 0.4712193310649043 +20 ENSG0000010000 Tgd 3270 G C chr20:3270:G:C -179985 0.820536380971562 0.8713230358630082 -0.554152905588382 0.6603731495658803 +20 ENSG0000010000 Tgd 6529 A C chr20:6529:A:C -131797 0.6414817386076277 0.39967838436006087 0.9622993743965202 0.5366795167462431 +20 ENSG0000010000 Tgd 453 A C chr20:453:A:C -312759 0.5805897337387078 0.9835505728830871 -0.9234856052934746 0.5969746837327569 +20 ENSG0000010000 Tgd 5664 C G chr20:5664:C:G 135656 0.9842358493165899 0.11564578402933046 0.7990094658223992 0.19088869572779374 +20 ENSG0000010000 Tgd 728 G A chr20:728:G:A 45175 0.9255751654990827 0.5384519970927919 0.438859998289691 0.742208127761637 +20 ENSG0000010000 Tgd 3229 C G chr20:3229:C:G -426628 0.9488744859713143 0.9207708562180402 0.24631081989281833 0.6637240887892787 +20 ENSG0000010000 Tgd 2042 G C chr20:2042:G:C -78053 0.697208414194399 0.5544124776667937 -0.616319814019705 0.6652645047785587 +20 ENSG0000010000 Tgd 6212 T C chr20:6212:T:C -74200 0.5479372131356982 0.0004059396972875273 -0.4261725662621456 0.43045826183984476 +20 ENSG0000010000 Tgd 9503 C G chr20:9503:C:G -36754 0.4421597993048074 0.2137014009891003 -0.053627628181347475 0.901279645002426 +20 ENSG0000010000 Tgd 2781 A C chr20:2781:A:C 40490 0.6638538363049987 0.6192608053623755 -0.8132255998488747 0.9520476627900227 +20 ENSG0000010000 Tgd 3849 C T chr20:3849:C:T 345742 0.19912993272657664 0.024425387726826342 -0.5103149118432997 0.4756612078745863 +20 ENSG0000010000 Tgd 1194 T G chr20:1194:T:G 18392 0.3996528628765377 0.1475713450912982 0.37524482616103905 0.8927671663851552 +20 ENSG0000010000 Tgd 1747 G T chr20:1747:G:T -315570 0.804109856173143 0.6959117764082383 -0.07090023085149566 0.5578483882393619 +20 ENSG0000010000 Tgd 1989 G T chr20:1989:G:T 340346 0.46464323749823666 0.5311318858555887 0.11785058074373467 0.3179806595078823 +20 ENSG0000010000 Tgd 7252 T G chr20:7252:T:G -28068 0.25919154846501935 0.24723973750965955 0.27532287355231255 0.7660478706128683 +20 ENSG0000010000 Tgd 8541 G T chr20:8541:G:T -212064 0.4398725932649027 0.7135448626110564 -0.5310128439707293 0.33651168908469264 +20 ENSG0000010000 Tgd 8850 A T chr20:8850:A:T -341843 0.23126147972818678 0.6939498122990523 0.41283828338910444 0.0651646218631642 +20 ENSG0000010000 Tgd 6679 C G chr20:6679:C:G -64030 0.06226571058358532 0.8328911693404877 -0.22104637466611754 0.7700259765423486 +20 ENSG0000010000 Tgd 321 A C chr20:321:A:C -186882 0.7534751250593859 0.8534479505691046 0.9068606769402126 0.41960226134719203 +20 ENSG0000010000 Tgd 8948 T G chr20:8948:T:G -269920 0.2729353117632566 0.48564199379850037 -0.2222855935077439 0.6692047470022942 +20 ENSG0000010000 Tgd 6625 T G chr20:6625:T:G 464209 0.1276277972811607 0.6222569609740647 -0.9460670961897246 0.394626236083365 +20 ENSG0000010000 Tgd 9247 G T chr20:9247:G:T 408959 0.4616984440515117 0.05028463348862755 -0.24179227162372086 0.21244862392727004 +20 ENSG0000010000 Tgd 5356 C G chr20:5356:C:G -208227 0.7520098235547849 0.8319242851552726 -0.4954569364352388 0.08282432652888091 +20 ENSG0000010000 Tgd 318 A C chr20:318:A:C -264887 0.650144093249875 0.7812330496108949 0.30350931048777885 0.7544789708554667 +20 ENSG0000010000 Tgd 4052 T A chr20:4052:T:A 151517 0.15238234578479037 0.12622097487420625 0.33891768923982135 0.5644056123480891 +20 ENSG0000010000 Tgd 3572 G C chr20:3572:G:C 304150 0.3688951743229414 0.6058926925603113 0.9274694882024175 0.7186388713674122 +20 ENSG0000010000 Tgd 2684 C A chr20:2684:C:A 106794 0.025678425497466018 0.3119572443946952 0.3546945737008176 0.9582146653676901 +20 ENSG0000010000 Tgd 6499 T A chr20:6499:T:A 120859 0.6906144159329803 0.6272423956010444 -0.7961973891080469 0.7727084040662728 +20 ENSG0000010000 Tgd 9838 C G chr20:9838:C:G 193655 0.3705708762180562 0.5059607896770779 -0.31753765027743364 0.8497260513725777 +20 ENSG0000010000 Tgd 8032 A G chr20:8032:A:G -120219 0.6355851061014459 0.8287073110024582 0.41461728741215387 0.43605165786266936 +20 ENSG0000010000 Tgd 8549 C G chr20:8549:C:G -12545 0.4355744930038943 0.7310262143051223 -0.46320892390154933 0.8518614468593125 +20 ENSG0000010000 Tgd 1420 C G chr20:1420:C:G -244291 0.7504762818270062 0.5698496446783222 0.33637694089098713 0.3370602232714839 +20 ENSG0000010000 Tgd 8099 C T chr20:8099:C:T 11233 0.212119850179739 0.7978323568280965 -0.3193223136714327 0.8804396597784672 +20 ENSG0000010000 Tgd 4527 A T chr20:4527:A:T -410229 0.24135605037267993 0.40642812467051925 0.11035242316372162 0.24108361218809132 +20 ENSG0000010000 Tgd 7801 C T chr20:7801:C:T -75955 0.6917871552952018 0.3062060301300884 0.16311117066473435 0.47378722827076525 +20 ENSG0000010000 Tgd 8699 C G chr20:8699:C:G 282169 0.5503884727566786 0.3518105276141683 -0.09250947429364298 0.3073163683574816 +20 ENSG0000010000 Tgd 3778 A T chr20:3778:A:T -169124 0.11955474125505283 0.5358639653837498 0.5243792189682059 0.1859646925952243 +20 ENSG0000010000 Tgd 3546 G C chr20:3546:G:C 259782 0.5895869059607909 0.7602078953730826 0.19358148102460349 0.9805301198320505 +20 ENSG0000010000 Tgd 3181 C T chr20:3181:C:T -121589 0.17944154368540333 0.014148367256063832 0.06827017853532658 0.275037015456484 +20 ENSG0000010000 Tgd 894 C T chr20:894:C:T 168854 0.868461197262944 0.49087869452377886 0.7454394699970692 0.5744901554067059 +20 ENSG0000010000 Tgd 7691 C T chr20:7691:C:T -446128 0.2524783904929726 0.8617229646275132 -0.7718257185501509 0.06627809167881855 +20 ENSG0000010000 Tgd 8057 C A chr20:8057:C:A -239753 0.11845156221146158 0.7644434453261942 0.21263530248592555 0.790950089013576 +20 ENSG0000010000 Tgd 3698 G C chr20:3698:G:C 401950 0.5885251387211029 0.4288298361404258 0.13725894124846638 0.0611700740681683 +20 ENSG0000010000 Tgd 1626 C A chr20:1626:C:A -335314 0.2398651776746924 0.551992245577759 -0.6869347691137238 0.4091090550873666 +20 ENSG0000010000 Tgd 9730 G C chr20:9730:G:C -465775 0.23147623455602584 0.7069558298790333 0.4059751161874343 0.4545772950806362 +20 ENSG0000010000 Tgd 3825 C T chr20:3825:C:T -54210 0.11477630246104575 0.22480945026602384 -0.7020211978493416 0.26636683916899956 +20 ENSG0000010000 Tgd 2331 T C chr20:2331:T:C 123948 0.7489577220696233 0.5692070493190924 -0.4227788233883165 0.12522930451653352 +20 ENSG0000010000 Tgd 4983 G C chr20:4983:G:C 24783 0.539981562598014 0.437758863571598 0.19607332408220723 0.8895334664031611 +20 ENSG0000010000 Tgd 5281 C A chr20:5281:C:A -404237 0.22892441572182698 0.6742983671721712 0.7210337456345424 0.5875358087780735 +20 ENSG0000010000 Tgd 340 C A chr20:340:C:A 300177 0.7562688304125571 0.47050082325163356 0.3030189788673727 0.9161567151388408 +20 ENSG0000010000 Tgd 2974 A G chr20:2974:A:G -135137 0.4083480934300153 0.32105825595657156 -0.7908002308348852 0.16166402780617667 +20 ENSG0000010000 Tgd 6745 G C chr20:6745:G:C 194769 0.9451935395632106 0.8135660347379726 0.10019321794356584 0.4553710826931277 +20 ENSG0000010000 Tgd 5154 A G chr20:5154:A:G 406924 0.5145962523291051 0.9881192147817541 0.31532077296625793 0.5430510007628379 +20 ENSG0000010000 Tgd 6771 A T chr20:6771:A:T 43623 0.36177935915167525 0.7564431540555737 0.25081748429001793 0.760230545524956 +20 ENSG0000010000 Tgd 3336 C T chr20:3336:C:T 472735 0.2880291449883289 0.8808466173578056 -0.030576406100003783 0.029840572999221566 +20 ENSG0000010000 Tgd 9976 C A chr20:9976:C:A 79077 0.4079906872899025 0.22470065945578466 0.6828113632340711 0.1143476567863407 +20 ENSG0000010000 Tgd 1925 T G chr20:1925:T:G 477957 0.7166033259917911 0.5088720150695117 -0.4531502065734516 0.8348892216311177 +20 ENSG0000010000 Tgd 7737 T G chr20:7737:T:G 78043 0.14464196848560873 0.19061037094792832 0.19875519734979985 0.7465462529469052 +20 ENSG0000010000 Tgd 2237 A C chr20:2237:A:C 310208 0.7900061820031135 0.41494242355134514 0.8684967873650402 0.5082299381338468 +20 ENSG0000010000 Tgd 43 G T chr20:43:G:T -31762 0.5385805777038737 0.34512394169300753 0.10383483414162198 0.5438866328957144 +20 ENSG0000010000 Tgd 7461 C T chr20:7461:C:T 231380 0.23880554416624933 0.3829708489296022 0.7120259519747565 0.41136432045402854 +20 ENSG0000010000 Tgd 5214 G T chr20:5214:G:T 19389 0.9648244383709104 0.1262462698093887 0.9307071803537075 0.3326627092274324 +20 ENSG0000010000 Tgd 1645 G A chr20:1645:G:A 51499 0.910441677696467 0.015347597915260636 -0.711689168066105 0.8710620383778701 +20 ENSG0000010000 Tgd 2530 A G chr20:2530:A:G 319488 0.9692036305742172 0.3385612340514317 0.3854091971737641 0.6501868159266934 +20 ENSG0000010000 Tgd 5384 G C chr20:5384:G:C 157246 0.718717425222983 0.7594018093343636 0.7447660347970726 0.03686320073784889 +20 ENSG0000010000 Tgd 1122 T C chr20:1122:T:C -261464 0.746766366737927 0.4339714719231257 -0.8031137472336041 0.6341140809520105 +20 ENSG0000010000 Tgd 1647 G T chr20:1647:G:T 227712 0.29946608024406474 0.028947249397568098 -0.35125066643739555 0.057063108876901907 +20 ENSG0000010000 Tgd 5874 C G chr20:5874:C:G -347360 0.2441974321839684 0.4120517489755754 0.3636007427054564 0.1808768292651598 +20 ENSG0000010000 Tgd 2869 A G chr20:2869:A:G 149813 0.6831345799627139 0.49766725236795106 0.16631426130410598 0.23295625585085714 +20 ENSG0000010000 Tgd 4162 G C chr20:4162:G:C 199233 0.009397431454871041 0.8046330769751463 0.802418847197766 0.6779332748133804 +20 ENSG0000010000 Tgd 2589 A G chr20:2589:A:G 491151 0.3455656244430817 0.5875717051264214 0.2778774047200243 0.4248846295224368 +20 ENSG0000010000 Tgd 4098 G C chr20:4098:G:C -291106 0.9993735655001792 0.8533354586601858 -0.7866934651552782 0.3819829333599714 +20 ENSG0000010000 Tgd 5882 A G chr20:5882:A:G -212187 0.008097965761490244 0.865067397697266 0.5566232315401558 0.9736292140110969 +20 ENSG0000010000 Tgd 9936 G C chr20:9936:G:C 313423 0.7988601195075987 0.607064998164266 -0.29535808832936694 0.636981260127886 +20 ENSG0000010000 Tgd 4107 T A chr20:4107:T:A 447287 0.6274581078167305 0.039422573960817386 0.5772209680203078 0.0343311667143868 +20 ENSG0000010000 Tgd 5978 T A chr20:5978:T:A 453813 0.2951104516291553 0.7474808649383715 -0.6487198591113867 0.13302763794903677 +20 ENSG0000010000 Tgd 8838 T C chr20:8838:T:C 458449 0.8246898125424073 0.4818478298737412 0.612976987587533 0.746812791366328 +20 ENSG0000010000 Tgd 5550 A G chr20:5550:A:G -421043 0.14075701500588267 0.9665002094627521 0.7202811937976437 0.7244924953634426 +20 ENSG0000010000 Tgd 6512 C A chr20:6512:C:A 329090 0.39457456032871197 0.2644585783524238 -0.7528225264730153 0.36921707295742295 +20 ENSG0000010000 Tgd 4296 G C chr20:4296:G:C -386391 0.674836555375322 0.4714768679814386 0.2390937340890591 0.9432259669217912 +20 ENSG0000010000 Tgd 5375 T A chr20:5375:T:A 166269 0.8238553513904476 0.909387638427892 -0.39561965094149953 0.4088875599396173 +20 ENSG0000010000 Tgd 2291 C G chr20:2291:C:G -378239 0.0971919986218216 0.8872593085285023 -0.728671902587327 0.4541901131320037 +20 ENSG0000010000 Tgd 8851 G T chr20:8851:G:T 428423 0.4148845274368069 0.0990216347105285 -0.02130592442077095 0.4087077698120028 +20 ENSG0000010000 Tgd 4584 A C chr20:4584:A:C -272177 0.44338308606070165 0.950555169851427 0.7109003866119092 0.10025526998152419 +20 ENSG0000010000 Tgd 6019 C A chr20:6019:C:A -82521 0.27588144086158684 0.9682068759363868 0.8980215765242752 0.8243668908496399 +20 ENSG0000010000 Tgd 1502 T A chr20:1502:T:A -446965 0.7867945904546167 0.24356889716402363 -0.7481522293839142 0.5650133979320554 +20 ENSG0000010000 Tgd 1125 T C chr20:1125:T:C 311984 0.1475541799414437 0.9005310356317582 -0.9943288970399673 0.8585477202537961 +20 ENSG0000010000 Tgd 2371 T C chr20:2371:T:C 337302 0.17449712090139347 0.6610576425973168 -0.9484397004276033 0.01584546690347814 +20 ENSG0000010000 Tgd 3899 C A chr20:3899:C:A -317290 0.26536750832497336 0.12675854371278028 -0.15807888617984167 0.11453565747976006 +20 ENSG0000010000 Tgd 1042 C A chr20:1042:C:A -26038 0.5038386897858214 0.9454156429701063 -0.9132699262016566 0.7834437689843992 +20 ENSG0000010000 Tgd 8544 C G chr20:8544:C:G 174591 0.9640261831220287 0.06082540749450582 -0.04203617800327342 0.40221563725804793 +20 ENSG0000010000 Tgd 1769 C T chr20:1769:C:T -431128 0.12619158830505606 0.6243174942812079 0.17072937709624214 0.7124406436298806 +20 ENSG0000010000 Tgd 6241 C G chr20:6241:C:G 30108 0.6054267915353129 0.09917846167904198 0.40355883709213236 0.8529399445582795 +20 ENSG0000010000 Tgd 9034 T G chr20:9034:T:G -26511 0.888091021988493 0.4138135711769134 0.6548384495600894 0.3993314540726963 +20 ENSG0000010000 Tgd 1558 C G chr20:1558:C:G -172296 0.6651078630603089 0.37430102343553684 -0.6947221504625525 0.92306205069865 +20 ENSG0000010000 Tgd 1100 A G chr20:1100:A:G -398745 0.744588969191879 0.3726468593759036 -0.7397690928523133 0.06092099699287572 +20 ENSG0000010000 Tgd 9202 C A chr20:9202:C:A -69236 0.35359807963376766 0.6653405200029154 0.5005685005029565 0.8682240567201959 +20 ENSG0000010000 Tgd 843 C A chr20:843:C:A 105991 0.5074125469680041 0.15473017585826143 -0.03562120759122278 0.8474275732868176 +20 ENSG0000010000 Tgd 5737 C A chr20:5737:C:A 299649 0.2785682124949992 0.22615909432784742 -0.1417751782364376 0.5614047360462848 +20 ENSG0000010000 Tgd 9122 A C chr20:9122:A:C -469641 0.1804160719608544 0.7026987728656047 -0.3820306223401797 0.34048483212048114 +20 ENSG0000010000 Tgd 101 G A chr20:101:G:A -351234 0.7409690591184199 0.971810318758019 -0.8164846338911094 0.5309522059702705 +20 ENSG0000010000 Tgd 6164 C T chr20:6164:C:T -111972 0.3116373697042164 0.3243828920784265 0.8828148479401103 0.5966275484328871 +20 ENSG0000010000 Tgd 862 C G chr20:862:C:G 194093 0.4240147731129952 0.6070760074410154 -0.17163252423455067 0.21635339637240908 +20 ENSG0000010000 Tgd 8395 A C chr20:8395:A:C -49203 0.11088977220093055 0.6782178929335344 0.1862685007845275 0.5274071730409967 +20 ENSG0000010000 Tgd 5054 A T chr20:5054:A:T -85537 0.9844456583211195 0.054781958518080986 -0.5911537512925364 0.9453787631394173 +20 ENSG0000010000 Tgd 2249 C A chr20:2249:C:A -491895 0.49738532861332685 0.43065501135360296 -0.7416285964815701 0.5330497655195563 +20 ENSG0000010000 Tgd 3771 C A chr20:3771:C:A -83641 0.8617643620225885 0.04230226156279138 -0.9625169268287086 0.92124127206791 +20 ENSG0000010000 Tgd 5130 G C chr20:5130:G:C -379232 0.4050323070649545 0.9661996910331262 -0.656253638843862 0.9476666950174207 +20 ENSG0000010000 Tgd 7539 C A chr20:7539:C:A -42075 0.8444843598146969 0.24331647482273366 0.17774257660582382 0.524438580457631 +20 ENSG0000010000 Tgd 6485 T C chr20:6485:T:C 316964 0.16813270804568659 0.5104832845421483 -0.7719467203228949 0.510442110260649 +20 ENSG0000010000 Tgd 5725 C T chr20:5725:C:T -252255 0.10280452777776283 0.25596822200172986 -0.6530019551158104 0.1537169192169239 +20 ENSG0000010000 Tgd 1235 T G chr20:1235:T:G -13510 0.7544458252469858 0.7598771496077484 -0.10218948600987399 0.9242301041272737 +20 ENSG0000010000 Tgd 9249 T G chr20:9249:T:G -428397 0.4689210835263733 0.6313851200254293 0.5926593583028563 0.59182833707419 +20 ENSG0000010000 Tgd 5767 A C chr20:5767:A:C -15828 0.4519138637006822 0.05689005083395238 0.6633932633262429 0.07765427017228153 +20 ENSG0000010000 Tgd 1480 A G chr20:1480:A:G 453207 0.8098159176979711 0.6518374546486099 -0.3569464742391433 0.4761533989151264 +20 ENSG0000010000 Tgd 2472 A G chr20:2472:A:G -391471 0.8109668113226207 0.8373771782475543 0.9647711621867947 0.08524480289253926 +20 ENSG0000010000 Tgd 2828 A T chr20:2828:A:T 241995 0.437758274309233 0.4394217917626243 0.04549607053109117 0.15958746177355984 +20 ENSG0000010000 Tgd 6109 C G chr20:6109:C:G -71375 0.7744647885737355 0.6788977205595811 -0.8952689649279875 0.6312556878675375 +20 ENSG0000010000 Tgd 5483 A C chr20:5483:A:C -400904 0.5579632124184023 0.38656420472373787 -0.49600843006769346 0.85171469372442 +20 ENSG0000010000 Tgd 9875 T C chr20:9875:T:C -414539 0.5827395145864196 0.14142838058431784 -0.30035842492831155 0.9677288111850518 +20 ENSG0000010000 Tgd 6422 T A chr20:6422:T:A -175380 0.5589220700910635 0.6434932633613195 -0.34304689149283196 0.12866597033624558 +20 ENSG0000010000 Tgd 8625 A G chr20:8625:A:G 33188 0.3618280963467846 0.3625976689820444 -0.6394741542463107 0.21497846854769145 +20 ENSG0000010000 Tgd 7968 A C chr20:7968:A:C 385447 0.7881201736714002 0.5076897127246462 0.07954151682734212 0.7389053589984661 +20 ENSG0000010000 Tgd 8627 A C chr20:8627:A:C 418964 0.7663076044472416 0.13104904142950802 -0.24656025835495066 0.16308496487636204 +20 ENSG0000010000 Tgd 2713 G A chr20:2713:G:A -69184 0.36429941413076905 0.71958567379065 0.9391772068172499 0.6109848267036899 +20 ENSG0000010000 Tgd 7356 C G chr20:7356:C:G 447885 0.8351133927257074 0.3678409582250328 0.8942603404882459 0.9844553537380457 +20 ENSG0000010000 Tgd 7565 C G chr20:7565:C:G 27335 0.5274597884614827 0.9662681532059473 0.6337824791624802 0.8014579649273961 +20 ENSG0000010000 Tgd 2268 C A chr20:2268:C:A 172324 0.480590655461825 0.3712121066044326 0.8685871079949994 0.7116895761418818 +20 ENSG0000010000 Tgd 8453 A C chr20:8453:A:C -412051 0.7631168302916909 0.2727912995913566 0.8106124179564824 0.14820130733561268 +20 ENSG0000010000 Tgd 7168 A T chr20:7168:A:T 356375 0.45112799022070893 0.3495850781386489 -0.9466596183941229 0.05420363028390339 +20 ENSG0000010000 Tgd 8225 C T chr20:8225:C:T -95076 0.9945253512382912 0.3749126734177676 -0.9436249089436999 0.9308950788452032 +20 ENSG0000010000 Tgd 5494 A C chr20:5494:A:C 461959 0.8297615831528226 0.6960719885759836 -0.7224146163636276 0.7058306391137913 +20 ENSG0000010000 Tgd 7350 A C chr20:7350:A:C -273870 0.834963099282381 0.5488042454438354 0.4544695706498636 0.5282437343808376 +20 ENSG0000010000 Tgd 1822 C T chr20:1822:C:T -184221 0.12184834515861753 0.23843950345982268 0.27790346434562063 0.6231877577726281 +20 ENSG0000010000 Tgd 1030 A G chr20:1030:A:G 125726 0.5360537843140613 0.6319549420131424 0.15009491506126715 0.7188257834645603 +20 ENSG0000010000 Tgd 4773 G A chr20:4773:G:A 144674 0.3528160396260338 0.5706637160224288 -0.625372176403235 0.6685466880167151 +20 ENSG0000010000 Tgd 8577 C A chr20:8577:C:A 499716 0.5260594453221705 0.5073276965797866 0.9766629711929349 0.5545978004657773 +20 ENSG0000010000 Tgd 6398 G A chr20:6398:G:A 166549 0.38688132152735755 0.3733023871008325 0.4946331831252906 0.3577367826382182 +20 ENSG0000010000 Tgd 1107 C T chr20:1107:C:T 268544 0.6571044000108314 0.10366386749968948 0.16380664311628013 0.7569222475155152 +20 ENSG0000010000 Tgd 2186 A C chr20:2186:A:C 72536 0.33854725817970077 0.6427956162027204 0.6607673135272054 0.6849978838425745 +20 ENSG0000010000 Tgd 7841 A G chr20:7841:A:G -461220 0.29344257117503125 0.043806275659123095 -0.6010603325696233 0.042864035988451614 +20 ENSG0000010000 Tgd 5081 C A chr20:5081:C:A 289882 0.6469004988007503 0.28611089555154867 0.7242770609385007 0.048756230212244886 +20 ENSG0000010000 Tgd 5439 C A chr20:5439:C:A 338171 0.368019174314673 0.8894865170122814 0.48661541103924244 0.8947428574600982 +20 ENSG0000010000 Tgd 6335 C T chr20:6335:C:T 20306 0.692068491112615 0.36734692695968196 0.5945817607533312 0.2674539751063804 +20 ENSG0000010000 Tgd 1354 G A chr20:1354:G:A -48476 0.6024532988302272 0.8223412795398867 0.09094879468927397 0.3218902167863794 +20 ENSG0000010000 Tgd 1312 C G chr20:1312:C:G 131894 0.7176629113116567 0.16664477206591366 -0.11218323779781203 0.44768253001058694 +20 ENSG0000010000 Tgd 5777 G C chr20:5777:G:C 170532 0.9800272791942791 0.9479043786030863 -0.8499176700236815 0.6378750253454151 +20 ENSG0000010000 Tgd 5953 T A chr20:5953:T:A -350285 0.8486693099705346 0.6780888719954488 -0.1236543501198446 0.12710379427795201 +20 ENSG0000010000 Tgd 3867 G A chr20:3867:G:A 134487 0.1534381633927081 0.44992256871479397 -0.2580709848997984 0.44449534988642775 +20 ENSG0000010000 Tgd 1260 T C chr20:1260:T:C -82632 0.31438544131488155 0.27868976629981135 0.9210401045299859 0.026887427523279064 +20 ENSG0000010000 Tgd 3049 A C chr20:3049:A:C 312609 0.26028977113990337 0.4462731124056162 0.9927302243095215 0.28629130082045984 +20 ENSG0000010000 Tgd 8048 T A chr20:8048:T:A -357679 0.8528262903843227 0.45204268524539737 0.7973580615724607 0.4456660815497126 +20 ENSG0000010000 Tgd 1439 A C chr20:1439:A:C 434629 0.2999566782367382 0.1575052493200384 0.41912758242077297 0.7005190367107267 +20 ENSG0000010000 Tgd 2853 C T chr20:2853:C:T -372743 0.9851325467301932 0.7920656736111408 -0.526527631426259 0.49452791550947534 +20 ENSG0000010000 Tgd 5913 C G chr20:5913:C:G 342700 0.9830119576427857 0.12977122971377042 0.7684928936692399 0.06668235716209871 +20 ENSG0000010000 Tgd 6524 G A chr20:6524:G:A -368586 0.9723797315137659 0.6423385893863813 -0.10005100867400785 0.6804288816589313 +20 ENSG0000010000 Tgd 5645 T G chr20:5645:T:G 27290 0.9107122709468873 0.05541285001777707 -0.7516777587219756 0.1538624513433904 +20 ENSG0000010000 Tgd 2698 T C chr20:2698:T:C 480143 0.7093321325292459 0.34602308234187307 0.8818081098630695 0.8950309909043033 +20 ENSG0000010000 Tgd 1293 C T chr20:1293:C:T 165905 0.9563516270431981 0.2744510332135133 0.25004472289718094 0.6148138500298899 +20 ENSG0000010000 Tgd 1531 T C chr20:1531:T:C 383456 0.9239297253163012 0.041194303521784104 0.7275623832400662 0.08214163203847652 +20 ENSG0000010000 Tgd 9450 C T chr20:9450:C:T 304214 0.5721372024460641 0.6181084263249575 -0.9394282028371386 0.8891078845675054 +20 ENSG0000010000 Tgd 8939 G T chr20:8939:G:T 343776 0.8073493144287976 0.4060925267445584 -0.09291173408965747 0.6889249581013107 +20 ENSG0000010000 Tgd 2590 T C chr20:2590:T:C 136129 0.1436686911626346 0.8614850768324948 -0.36136721470654387 0.9880353460976227 +20 ENSG0000010000 Tgd 5659 G T chr20:5659:G:T 297615 0.37054019805029126 0.5616512157483692 -0.3617682271936855 0.4670060944735958 +20 ENSG0000010000 Tgd 4383 G T chr20:4383:G:T -352280 0.09681165256057145 0.2902120049699015 -0.23170033299678794 0.6157620667198047 +20 ENSG0000010000 Tgd 4068 T C chr20:4068:T:C 479109 0.5776870378935964 0.31271492086227304 0.5262427502772571 0.4987672765178489 +20 ENSG0000010000 Tgd 8434 C G chr20:8434:C:G -475698 0.09004909504378433 0.39324218411329726 -0.08553871562053827 0.24148791202850092 +20 ENSG0000010000 Tgd 9558 C A chr20:9558:C:A -447005 0.28135633837352836 0.5975187710101862 0.6856992938259248 0.6728480831616839 +20 ENSG0000010000 Tgd 4682 G T chr20:4682:G:T 425321 0.26447289979091326 0.365777639775401 -0.19349185577128303 0.0461971521167534 +20 ENSG0000010000 Tgd 839 T C chr20:839:T:C 80096 0.28860169703909566 0.3863488249797785 -0.09929123871916379 0.5503072324279021 +20 ENSG0000010000 Tgd 1947 T A chr20:1947:T:A -86963 0.37319833632482 0.9867876644364394 0.11566367654425735 0.3662407668397591 +20 ENSG0000010000 Tgd 2364 T G chr20:2364:T:G 24369 0.040254906157429104 0.03891396624622023 0.4271836926496133 0.8041618893390178 +20 ENSG0000010000 Tgd 8509 G T chr20:8509:G:T 135710 0.8931316920780072 0.1397809857723552 0.8627374710599798 0.31921150172754775 +20 ENSG0000010000 Tgd 6439 G C chr20:6439:G:C -2040 0.8157488332438242 0.3683578098657696 0.3476127849460331 0.9799181331479827 +20 ENSG0000010000 Tgd 9564 C A chr20:9564:C:A 125905 0.4745902140850605 0.9670706961720509 0.5658079828628428 0.7763858631469001 +20 ENSG0000010000 Tgd 9464 T A chr20:9464:T:A 111868 0.480448783714414 0.524232332624683 0.4423656704982488 0.7748315237039771 +20 ENSG0000010000 Tgd 6230 T A chr20:6230:T:A -37538 0.3136924834458552 0.15143125811934544 0.3810005218370509 0.41096703191338235 +20 ENSG0000010000 Tgd 7727 A T chr20:7727:A:T 43878 0.2073417049712447 0.3250495344260548 0.3244535994286981 0.5259516742486353 +20 ENSG0000010000 Tgd 5141 T G chr20:5141:T:G 456431 0.533127064573221 0.5462732192448302 0.351737153112736 0.8677867490515383 +20 ENSG0000010000 Tgd 4332 G T chr20:4332:G:T -241506 0.2790063959217567 0.29849916119029396 0.8829710926549228 0.9822780361795198 +20 ENSG0000010000 Tgd 4736 T G chr20:4736:T:G -167559 0.4798034232020614 0.5604875902362195 0.8689707785160146 0.7219427142156963 +20 ENSG0000010000 Tgd 4716 A G chr20:4716:A:G 439272 0.9801605373213622 0.8183774601305623 0.9092177267829227 0.8048112181226138 +20 ENSG0000010000 Tgd 4759 A C chr20:4759:A:C 248831 0.07902943600985035 0.9240096318898805 0.31194410110181514 0.747591161218287 +20 ENSG0000010000 Tgd 3506 T C chr20:3506:T:C 478346 0.5620180196774848 0.2716214667057466 -0.78154683685784 0.7411500857118045 +20 ENSG0000010000 Tgd 3921 T A chr20:3921:T:A 202371 0.9051841909515969 0.2256716462816638 -0.5343268803880945 0.10109776108628558 +20 ENSG0000010000 Tgd 5412 G A chr20:5412:G:A 214281 0.7707660580982791 0.00518144640713003 0.10070513155923333 0.9291705804898078 +20 ENSG0000010000 Tgd 6667 T C chr20:6667:T:C -163232 0.28541534130199187 0.05916258624149073 0.5374499870756375 0.6526464316886605 +20 ENSG0000010000 Tgd 3805 A T chr20:3805:A:T -61816 0.8822449731648332 0.17578870753886255 0.839269623701868 0.9971746312854214 +20 ENSG0000010000 Tgd 6505 G T chr20:6505:G:T 482105 0.7490032014409554 0.8722906852218486 -0.4210660475977783 0.0384287097473286 +20 ENSG0000010000 Tgd 4889 A C chr20:4889:A:C -201616 0.45434907815679504 0.6413124095149374 0.04863706967104098 0.8893707038061466 +20 ENSG0000010000 Tgd 2199 G C chr20:2199:G:C -297823 0.8088138782430199 0.33068409683178557 0.4622384676175484 0.6486370533705325 +20 ENSG0000010000 Tgd 3051 A C chr20:3051:A:C 329179 0.295024257658282 0.6744011398947444 -0.6136774245575829 0.611343545163351 +20 ENSG0000010000 Tgd 6644 G C chr20:6644:G:C -409049 0.4008332466278661 0.09538510579452808 0.9633703848810773 0.4779766443914031 +20 ENSG0000010000 Tgd 4065 A C chr20:4065:A:C -97794 0.2355212528015339 0.753756651781457 0.9080696453098251 0.3026438938519231 +20 ENSG0000010000 Tgd 9387 A C chr20:9387:A:C 185436 0.3595520905611559 0.23630257742199545 0.3355722295973427 0.46592959595098743 +20 ENSG0000010000 Tgd 2617 G C chr20:2617:G:C 223821 0.11741574584477632 0.9161303858506353 -0.4099247996875064 0.6150108226957052 +20 ENSG0000010000 Tgd 3591 T G chr20:3591:T:G -339374 0.4549786727706703 0.9888379618953089 -0.2527503160261273 0.7022387861287985 +20 ENSG0000010000 Tgd 7715 A G chr20:7715:A:G 53829 0.7037661251558726 0.07810272214744018 0.12833744454694962 0.0626962895091271 +20 ENSG0000010000 Tgd 8973 T C chr20:8973:T:C 395993 0.520341541184787 0.11624002218466423 -0.5891970289212769 0.5835645307625765 +20 ENSG0000010000 Tgd 1490 G A chr20:1490:G:A -24542 0.131944339821099 0.4154245738446598 0.12782237019742682 0.5592384017997676 +20 ENSG0000010000 Tgd 5050 A G chr20:5050:A:G -233183 0.8164532259331305 0.7458044828318157 0.1566225301180708 0.04624451292510096 +20 ENSG0000010000 Tgd 5645 A G chr20:5645:A:G -466724 0.2870907068913201 0.17998132682570855 -0.7291422670211245 0.641883475172184 +20 ENSG0000010000 Tgd 6888 C G chr20:6888:C:G -29675 0.8696202853107085 0.9067673115245726 -0.24870893239602476 0.6830476237474399 +20 ENSG0000010000 Tgd 8836 T C chr20:8836:T:C -375605 0.17847362900411168 0.5372584863980012 0.057685079088018565 0.728130282765222 +20 ENSG0000010000 Tgd 3649 C G chr20:3649:C:G 206215 0.719093975010852 0.4241280297334016 -0.24144706393241244 0.23043440272111085 +20 ENSG0000010000 Tgd 7547 C T chr20:7547:C:T -210961 0.1884804512367424 0.8752081746237274 0.5309798585302328 0.03318509759507105 +20 ENSG0000010000 Tgd 6869 A T chr20:6869:A:T -283908 0.06729090288949535 0.5939441474793573 -0.10711786750279528 0.6723516132353468 +20 ENSG0000010000 Tgd 798 T A chr20:798:T:A -78195 0.43896281148746064 0.5397598089074284 0.5087714174945688 0.7762875578432351 +20 ENSG0000010000 Tgd 2296 C T chr20:2296:C:T 355413 0.9163970331215671 0.576110335580287 0.15494962927576394 0.7727656742696416 +20 ENSG0000010000 Tgd 5254 T C chr20:5254:T:C 418823 0.14326043416332868 0.6602124238107432 -0.5579145191079349 0.30120045280366214 +20 ENSG0000010000 Tgd 999 T G chr20:999:T:G 82851 0.49562078749302096 0.9722902353436859 0.8831728196638235 0.6716711822209765 +20 ENSG0000010000 Tgd 8593 C G chr20:8593:C:G -71910 0.1492176078251637 0.37646018850713203 0.5088321944762506 0.4740453015918077 +20 ENSG0000010000 Tgd 3693 C T chr20:3693:C:T 344917 0.4630251594986109 0.05762393446554204 -0.17464502203783128 0.4170913587937464 +20 ENSG0000010000 Tgd 8684 T G chr20:8684:T:G -245345 0.2549956456075365 0.33026299362410494 -0.8418591332103893 0.45033703900341876 +20 ENSG0000010000 Tgd 6080 A T chr20:6080:A:T -445960 0.2684615878549812 0.6736719206345785 0.20584408997815173 0.8737468380310501 +20 ENSG0000010000 Tgd 3083 T G chr20:3083:T:G -280964 0.8694738515245379 0.3329643108188213 0.9140395210533463 0.016318372522264344 +20 ENSG0000010000 Tgd 3114 A G chr20:3114:A:G 458861 0.24259318184574152 0.6044015340787812 -0.5909737140442126 0.9152113331339629 +20 ENSG0000010000 Tgd 9046 A G chr20:9046:A:G 298625 0.8397311815636849 0.9143304988974891 -0.2585901571374831 0.41451624040804597 +20 ENSG0000010000 Tgd 9217 A C chr20:9217:A:C 80189 0.9347582502963535 0.5791429260374005 -0.16484385288965275 0.15325899877395913 +20 ENSG0000010000 Tgd 5405 T G chr20:5405:T:G 97467 0.8333627152869851 0.4993014823693225 0.3092159322420438 0.6851617657335602 +20 ENSG0000010000 Tgd 4217 G T chr20:4217:G:T 268367 0.7949755143536341 0.16926571086018172 0.4406270615241874 0.48882800493287826 +20 ENSG0000010000 Tgd 8883 A G chr20:8883:A:G -355830 0.8425447168253485 0.2314333920774455 0.4143391274069197 0.010132320228971106 +20 ENSG0000010000 Tgd 8286 G C chr20:8286:G:C -436614 0.617835235876803 0.6667547295533397 0.23303872216867583 0.48372094946820327 +20 ENSG0000010000 Tgd 7994 G A chr20:7994:G:A -482462 0.5294176468416506 0.274740737197832 0.9549586964650234 0.018125455004824775 +20 ENSG0000010000 Tgd 7055 T A chr20:7055:T:A 462643 0.09631389025140846 0.14889748574025052 -0.6161358860167736 0.526929529414816 +20 ENSG0000010000 Tgd 5808 C G chr20:5808:C:G -417143 0.37305158346368217 0.40602740987388597 0.13000436489593814 0.9902427986080876 +20 ENSG0000010000 Tgd 3701 C A chr20:3701:C:A 185491 0.9916747052834864 0.6498944517939228 -0.9366309926882312 0.405873019806182 +20 ENSG0000010000 Tgd 6180 G A chr20:6180:G:A 167678 0.009450172654130617 0.17138357522104763 -0.00028321377441598017 0.43447574231969066 +20 ENSG0000010000 Tgd 5428 G C chr20:5428:G:C -451177 0.9241592666085664 0.6844287434636415 -0.4392539724810176 0.5434876676272329 +20 ENSG0000010000 Tgd 540 T C chr20:540:T:C -483582 0.9614691898760058 0.5870361040844884 0.5045089396937301 0.7129986885494104 +20 ENSG0000010000 Tgd 6526 A C chr20:6526:A:C -329659 0.5639581996237649 0.5666959198910784 0.6988848505788534 0.6773579309108051 +20 ENSG0000010000 Tgd 8857 C G chr20:8857:C:G 292313 0.7397451709207191 0.7904980852341499 0.3786210823679501 0.07934926332750956 +20 ENSG0000010000 Tgd 5667 G T chr20:5667:G:T 379414 0.0760182465657051 0.6051687432006422 0.2277304672428726 0.5960130533822352 +20 ENSG0000010000 Tgd 5348 A C chr20:5348:A:C 321609 0.9925858784507974 0.49060345611079326 -0.2883776045883042 0.9412017021257547 +20 ENSG0000010000 Tgd 7076 T G chr20:7076:T:G -410144 0.7721674041346899 0.29537948070507625 -0.5071004373862069 0.0744331770386991 +20 ENSG0000010000 Tgd 4391 T G chr20:4391:T:G 246247 0.7838902818702227 0.15427689060311978 -0.22075604920568725 0.36133952788594637 +20 ENSG0000010000 Tgd 1500 A C chr20:1500:A:C -33661 0.3599174973468966 0.2697664432393865 -0.7349859910116012 0.18820439174434933 +20 ENSG0000010000 Tgd 7354 G A chr20:7354:G:A -472463 0.0896188419603875 0.554219805397572 0.19384911057418264 0.7846542855285547 +20 ENSG0000010000 Tgd 6312 A C chr20:6312:A:C -66089 0.3877995593783937 0.08469951692852251 0.8022720897128661 0.9053023667390455 +20 ENSG0000010000 Tgd 3978 T G chr20:3978:T:G -322265 0.13884005895941676 0.30113126537506874 -0.01375211557843059 0.06420388312667745 +20 ENSG0000010000 Tgd 7122 C G chr20:7122:C:G -185687 0.4842313139339285 0.07692136139515715 -0.49660052442219427 0.2473434782786559 +20 ENSG0000010000 Tgd 8124 T G chr20:8124:T:G -387832 0.13548952568067607 0.006767369425471514 -0.2086160431471884 0.841771773335129 +20 ENSG0000010000 Tgd 6225 C G chr20:6225:C:G -149004 0.4306162209471722 0.8235352401398752 0.3020737167332377 0.5947985261454309 +20 ENSG0000010000 Tgd 4923 C T chr20:4923:C:T 2278 0.31418328119544137 0.9645746230947939 0.937450443493391 0.29215670342847316 +20 ENSG0000010000 Tgd 8045 T C chr20:8045:T:C -105678 0.2803001464642175 0.7858665316770608 -0.269968925209525 0.9321350854358573 +20 ENSG0000010000 Tgd 3274 T A chr20:3274:T:A 499297 0.7272133638085589 0.9429749154177833 -0.580703207277433 0.7978878355103721 +20 ENSG0000010000 Tgd 1134 T C chr20:1134:T:C -246223 0.25268168493109167 0.15414323445585654 -0.15374408976619303 0.3776138272202847 +20 ENSG0000010000 Tgd 7358 G A chr20:7358:G:A 329130 0.9684280407393685 0.701634287055593 0.6245939513579901 0.5942261234115227 +20 ENSG0000010000 Tgd 1393 A T chr20:1393:A:T 189545 0.6646938871965469 0.16633849328011152 0.2253558046265942 0.5636570719154521 +20 ENSG0000010000 Tgd 6548 C G chr20:6548:C:G -388910 0.010547772784579967 0.25873837040365544 0.021352481050089356 0.5192789690825002 +20 ENSG0000010000 Tgd 9512 T G chr20:9512:T:G -107708 0.39113416867750284 0.772342232462432 0.17717991308029446 0.5009653158381148 +20 ENSG0000010000 Tgd 5652 A G chr20:5652:A:G -390373 0.2954322205184059 0.9205475446710576 -0.8282904011596839 0.8314864269624314 +20 ENSG0000010000 Tgd 2322 C G chr20:2322:C:G 322366 0.2068673262083145 0.48292599877938847 -0.04767493758167296 0.4387277723347541 +20 ENSG0000010000 Tgd 7413 C A chr20:7413:C:A -185151 0.04468305267532113 0.7107789897552524 -0.9548297695937753 0.34373486960919164 +20 ENSG0000010000 Tgd 1792 C G chr20:1792:C:G -15502 0.23185554741141035 0.40504743628025286 -0.6310964496972127 0.640838397783418 +20 ENSG0000010000 Tgd 7081 G A chr20:7081:G:A 273207 0.6141069373719198 0.19732443578224634 0.1844063167207366 0.3894469445753514 +20 ENSG0000010000 Tgd 3520 T C chr20:3520:T:C 288870 0.7037597433383002 0.7960080509078782 0.15469581040370528 0.7997028545298229 +20 ENSG0000010000 Tgd 8797 T C chr20:8797:T:C -158181 0.1970742751475455 0.11395497070516192 0.34140285644883717 0.48999449482699703 +20 ENSG0000010000 Tgd 5135 A C chr20:5135:A:C -130918 0.8455178026695592 0.617362679336425 0.6274765085218676 0.7062823725850341 +20 ENSG0000010000 Tgd 4874 A T chr20:4874:A:T -171601 0.11786165266165671 0.3053800025354989 -0.633910963337033 0.693743105174729 +20 ENSG0000010000 Tgd 8370 T G chr20:8370:T:G -56412 0.18575369929276564 0.6355016420586352 0.3868658530587106 0.6456148349848705 +20 ENSG0000010000 Tgd 2839 T G chr20:2839:T:G -197135 0.14029653509779705 0.3145800146608443 -0.09799805850669774 0.054557651368205985 +20 ENSG0000010000 Tgd 5883 A G chr20:5883:A:G -356833 0.19512849163424917 0.38394417586795304 0.12316415467020891 0.6534166908523058 +20 ENSG0000010000 Tgd 6704 T A chr20:6704:T:A 92862 0.030860705643004804 0.7610566185454242 -0.41582018088258677 0.2755780653552604 +20 ENSG0000010000 Tgd 8809 C T chr20:8809:C:T 318665 0.45732138727344906 0.742518251929787 0.5318391098873814 0.5501764583535133 +20 ENSG0000010000 Tgd 1855 A C chr20:1855:A:C 312764 0.5431061820930451 0.9908936200057101 0.08408675823525957 0.7570294561950035 +20 ENSG0000010000 Tgd 7232 T G chr20:7232:T:G -392609 0.735988697633674 0.6536717023800722 -0.504936750267313 0.8749350364306074 +20 ENSG0000010000 Tgd 529 G C chr20:529:G:C -134491 0.8621996254975243 0.08698300599358899 0.730580940752591 0.11826864047241215 +20 ENSG0000010000 Tgd 3883 T C chr20:3883:T:C 402874 0.7107539594937995 0.6327706309271385 -0.6680367646194816 0.14009573096084932 +20 ENSG0000010000 Tgd 3386 T A chr20:3386:T:A 97766 0.35081547895283094 0.281085018790198 0.07753709209527604 0.324329962238827 +20 ENSG0000010000 Tgd 4795 A T chr20:4795:A:T 286530 0.7856910482912973 0.9187687118298253 0.9849724512893487 0.8671805428433447 +20 ENSG0000010000 Tgd 2079 T C chr20:2079:T:C 368726 0.24755474002267108 0.8435556566434692 -0.2145984993955683 0.14302946144229248 +20 ENSG0000010000 Tgd 4403 G A chr20:4403:G:A 164406 0.7945986306676647 0.7688842348239927 -0.1942984533963581 0.7500525804903169 +20 ENSG0000010000 Tgd 6047 C A chr20:6047:C:A 411115 0.7741352904376932 0.732724026539487 0.46186387497410597 0.458990807423038 +20 ENSG0000010000 Tgd 5870 A G chr20:5870:A:G -271589 0.9681285800758235 0.8248476476360221 -0.010570104889022769 0.323542284440363 +20 ENSG0000010000 Tgd 4647 C T chr20:4647:C:T 93643 0.8524225762884162 0.7883036534766824 0.788309316077112 0.7624917684000794 +20 ENSG0000010000 Tgd 753 A G chr20:753:A:G -482928 0.12423717923039845 0.8576515999286138 -0.11742810224714684 0.0016752555805921066 +20 ENSG0000010000 Tgd 7010 C T chr20:7010:C:T 416899 0.9327255627259242 0.27401945809528216 0.30917592883758815 0.2511388892705598 +20 ENSG0000010000 Tgd 6093 T A chr20:6093:T:A -84406 0.6256042741649541 0.7259883634704453 0.5104643141350722 0.42980170981459126 +20 ENSG0000010000 Tgd 1495 T G chr20:1495:T:G -418276 0.1326997920399866 0.22619086145940603 0.3599654502431582 0.0102776606608517 +20 ENSG0000010000 Tgd 5630 A G chr20:5630:A:G 227744 0.13217515109256084 0.0708283054005121 -0.2338601486484546 0.7310326183822071 +20 ENSG0000010000 Tgd 1679 A C chr20:1679:A:C -114584 0.8809889949802706 0.13712929474354563 0.5469209673012483 0.7534046431900769 +20 ENSG0000010000 Tgd 2182 T A chr20:2182:T:A 56278 0.563291214469632 0.6103192392738179 -0.6717669004187075 0.35183653110794416 +20 ENSG0000010000 Tgd 3491 T G chr20:3491:T:G 146002 0.6865661698757399 0.85996252460215 -0.826623933068023 0.10136464736516115 +20 ENSG0000010000 Tgd 2018 G C chr20:2018:G:C -49754 0.31450366818216935 0.1398301888092337 -0.44606468611030925 0.08516446728198868 +20 ENSG0000010000 Tgd 9067 C A chr20:9067:C:A 389079 0.8470700208723945 0.8758271880570749 -0.5891085636951161 0.6073199428022878 +20 ENSG0000010000 Tgd 3091 G C chr20:3091:G:C 177558 0.05456913101525296 0.8979125603569896 0.9093430226943056 0.4953928322233236 +20 ENSG0000010000 Tgd 1848 T G chr20:1848:T:G 169077 0.5939297681377231 0.5282865009361842 0.9553938956866712 0.9868956503103458 +20 ENSG0000010000 Tgd 5186 T G chr20:5186:T:G 402628 0.8389733029036253 0.4208635342524384 0.09271244232270193 0.17359754183861023 +20 ENSG0000010000 Tgd 7718 C T chr20:7718:C:T -458239 0.9225792889331941 0.9486799969471246 -0.20404995222969946 0.28720131229566126 +20 ENSG0000010000 Tgd 8210 G A chr20:8210:G:A 171652 0.5365648160700154 0.616047055666748 -0.44506452853087985 0.31059697873102526 +20 ENSG0000010000 Tgd 8378 C G chr20:8378:C:G 114923 0.6342942473532567 0.8345264691847527 0.3621113694184208 0.06704896853759378 +20 ENSG0000010000 Tgd 4006 A G chr20:4006:A:G -378380 0.45337184229714267 0.6088324044274436 -0.3814198722529476 0.7419518155484968 +20 ENSG0000010000 Tgd 2878 T A chr20:2878:T:A -328210 0.49641293252271557 0.3467051276788514 0.03444568489472699 0.8226843658465501 +20 ENSG0000010000 Tgd 4248 T C chr20:4248:T:C -366904 0.749776384093791 0.8734600564000344 0.4658716751100831 0.11893866356208066 +20 ENSG0000010000 Tgd 481 C G chr20:481:C:G -214808 0.5238542114486693 0.26294965082647825 0.9501011755563566 0.6279053000658226 +20 ENSG0000010000 Tgd 8129 G C chr20:8129:G:C -441868 0.49961000576138326 0.5668861282384499 -0.26462444428637655 0.25586096495803906 +20 ENSG0000010000 Tgd 1686 A T chr20:1686:A:T 276764 0.5088248849106468 0.04403790726280954 0.7258569898052225 0.24530689890634674 +20 ENSG0000010000 Tgd 7730 C G chr20:7730:C:G 464927 0.15008466824115008 0.9311600771571855 0.7149703954959448 0.5533119237073687 +20 ENSG0000010000 Tgd 6871 T C chr20:6871:T:C -239678 0.41625659850131536 0.7202879214281971 -0.45748408398036666 0.07880918289694507 +20 ENSG0000010000 Tgd 6109 A G chr20:6109:A:G -427726 0.8769912381849748 0.8660322299771522 0.5470549590117708 0.311387076273364 +20 ENSG0000010000 Tgd 1416 G A chr20:1416:G:A -113161 0.20067115345295583 0.5638067408241869 -0.3921813854638341 0.6230948063682125 +20 ENSG0000010000 Tgd 7601 C G chr20:7601:C:G 310143 0.7758859559552551 0.7324633367392666 0.0931184852195115 0.7961775676375757 +20 ENSG0000010000 Tgd 2467 A G chr20:2467:A:G -474929 0.23299774185974298 0.3464236977394062 0.6791480137923478 0.8773214156373234 +20 ENSG0000010000 Tgd 5489 A G chr20:5489:A:G 390247 0.7380826601923632 0.30751063752136387 -0.5896112541882026 0.9831326261530028 +20 ENSG0000010000 Tgd 6879 G A chr20:6879:G:A -350711 0.7116524747001027 0.09302663835808822 0.8425488059442128 0.8973901844595278 +20 ENSG0000010000 Tgd 8516 G C chr20:8516:G:C -19272 0.9745547901682511 0.08490241751648953 -0.8088459893252289 0.134380336400706 +20 ENSG0000010000 Tgd 6462 G T chr20:6462:G:T -251727 0.2916760240569035 0.8509137057886191 0.8520839035632732 0.3935597182365125 +20 ENSG0000010000 Tgd 5346 C G chr20:5346:C:G -214834 0.2336112266383128 0.9435546860300945 -0.7277763071665619 0.7703764735394965 +20 ENSG0000010000 Tgd 1786 T A chr20:1786:T:A -327641 0.4495667477403217 0.3140332878121178 -0.7585265258561888 0.3589291584914184 +20 ENSG0000010000 Tgd 3402 G C chr20:3402:G:C -14146 0.2650079269147082 0.11991355635539358 -0.6847692458689676 0.6863687881075647 +20 ENSG0000010000 Tgd 9885 A T chr20:9885:A:T 376530 0.8565732712134246 0.1483237973690994 0.4223147965702232 0.9684316041721925 +20 ENSG0000010000 Tgd 6493 A C chr20:6493:A:C -227196 0.8200896158119784 0.17386773251803278 0.904193213647488 0.8547467033173811 +20 ENSG0000010000 Tgd 9109 T A chr20:9109:T:A -15513 0.10190734866184548 0.7938097427769977 -0.7570934889919025 0.0626075153093185 +20 ENSG0000010000 Tgd 3642 G C chr20:3642:G:C 219622 0.6302975486038245 0.6446850157085018 0.1646476028281263 0.25956183169417935 +20 ENSG0000010000 Tgd 1229 T G chr20:1229:T:G 348611 0.1287915489970045 0.9050779703801529 0.6587123544348359 0.33221834136102446 +20 ENSG0000010000 Tgd 700 G A chr20:700:G:A -323851 0.9241317255339339 0.4331563772386714 0.4488616942614121 0.49663026482204203 +20 ENSG0000010000 Tgd 6271 G T chr20:6271:G:T -128864 0.21471610597002666 0.18715111371116167 -0.4402908914385524 0.8835403750947325 +20 ENSG0000010000 Tgd 568 T C chr20:568:T:C 23125 0.41199220629616506 0.5506886652039805 -0.8780418621343145 0.2804962114515324 +20 ENSG0000010000 Tgd 2249 G T chr20:2249:G:T 173870 0.884652516224965 0.5258140582527797 0.26150877764951086 0.8023659146883564 +20 ENSG0000010000 Tgd 320 G C chr20:320:G:C 2985 0.5445178060340516 0.4846794854405083 0.825354033196734 0.502890862288198 +20 ENSG0000010000 Tgd 6364 C T chr20:6364:C:T -472671 0.31887756732937955 0.21902018807309453 0.7915295632286274 0.778759743047146 +20 ENSG0000010000 Tgd 960 G C chr20:960:G:C 304092 0.5839889198512267 0.23276212792083517 -0.6807503834346782 0.2486091969475713 +20 ENSG0000010000 Tgd 3952 C A chr20:3952:C:A 301164 0.9963920485064571 0.21941158604392486 0.6930101809302662 0.7975932966920294 +20 ENSG0000010000 Tgd 5814 T C chr20:5814:T:C 345372 0.7381051011206698 0.35878313268706197 0.1831249896914744 0.7037494300369935 +20 ENSG0000010000 Tgd 5762 G C chr20:5762:G:C -315916 0.49043642012747923 0.09025737685090285 -0.5347532838335218 0.2195901327498857 +20 ENSG0000010000 Tgd 8626 G A chr20:8626:G:A -152152 0.9178961859206465 0.20146438335214112 -0.7390209087616348 0.7172206950581254 +20 ENSG0000010000 Tgd 5302 A C chr20:5302:A:C -423946 0.3735907800833732 0.9419232134680416 -0.20880887529229142 0.10193113801050564 +20 ENSG0000010000 Tgd 4945 C T chr20:4945:C:T -334846 0.7323520254246408 0.4368683829295823 0.27853198290857817 0.48771281911083375 +20 ENSG0000010000 Tgd 5199 T C chr20:5199:T:C -265919 0.6655316694747667 0.8144542364429803 -0.24323178370560372 0.7342609783918406 +20 ENSG0000010000 Tgd 4826 A G chr20:4826:A:G 392083 0.9942831305476306 0.965183940287551 -0.9352345141458251 0.6027862787835202 +20 ENSG0000010000 Tgd 3620 A G chr20:3620:A:G -352525 0.3311684261660526 0.07780663846430125 -0.30637975063354306 0.32019916046201824 +20 ENSG0000010000 Tgd 1454 C G chr20:1454:C:G -488051 0.2652124405628762 0.2495408631352788 -0.8644104398715324 0.2574012836011721 +20 ENSG0000010000 Tgd 1771 G T chr20:1771:G:T 427519 0.4140191636464148 0.8817706583344382 -0.2975376614030605 0.3759722227702076 +20 ENSG0000010000 Tgd 7856 G A chr20:7856:G:A 338016 0.8457624840245603 0.29490861311613015 -0.36256618408668495 0.9517104693026864 +20 ENSG0000010000 Tgd 1216 C T chr20:1216:C:T 431063 0.37545788407999636 0.7319850852713169 0.09409251722446288 0.8982260489468535 +20 ENSG0000010000 Tgd 1526 C G chr20:1526:C:G 238726 0.030993204052174983 0.9424422581019638 -0.6700056104761718 0.8898635171336395 +20 ENSG0000010000 Tgd 2574 C T chr20:2574:C:T -300788 0.4092798657506458 0.5541124323162294 0.8511472006138265 0.5405853061750494 +20 ENSG0000010000 Tgd 4613 C T chr20:4613:C:T -399425 0.04963544303850986 0.5717698078577416 0.6797090096913021 0.15443634458221747 +20 ENSG0000010000 Tgd 5912 A G chr20:5912:A:G -408116 0.2945494489662148 0.6620202260098677 0.20043105602753752 0.2004751259601854 +20 ENSG0000010000 Tgd 422 C A chr20:422:C:A -3426 0.8437690743469366 0.3083534001177294 -0.20506530298375414 0.4896077153085366 +20 ENSG0000010000 Tgd 4342 A G chr20:4342:A:G -306138 0.37102052484074743 0.3814451871022706 -0.6268341176841368 0.04557230777317783 +20 ENSG0000010000 Tgd 7205 G C chr20:7205:G:C -262768 0.8370787521344571 0.5642465879145218 -0.6977386511529218 0.6967744800955131 +20 ENSG0000010000 Tgd 1585 A C chr20:1585:A:C 347438 0.5414490060060221 0.9707055371735758 0.17945288460720699 0.5540483042517509 +20 ENSG0000010000 Tgd 6343 T G chr20:6343:T:G -186631 0.07895504977408319 0.9027772013391541 0.4286113982607198 0.5025993688452892 +20 ENSG0000010000 Tgd 8468 T A chr20:8468:T:A 495365 0.7571887556391934 0.17287897280649445 0.9687359804982658 0.9721927134594192 +20 ENSG0000010000 Tgd 3158 T A chr20:3158:T:A -56060 0.07836852213948908 0.6831254693522546 -0.5961614400555311 0.82274146884381 +20 ENSG0000010000 Tgd 2423 G A chr20:2423:G:A 324758 0.7004121215869331 0.5875760877323299 0.5633713218509231 0.11340632378330788 +20 ENSG0000010000 Tgd 2452 T A chr20:2452:T:A 469857 0.10563482018324544 0.7795446969642522 0.571491260619355 0.8676077924974102 +20 ENSG0000010000 Tgd 5634 G C chr20:5634:G:C -98350 0.6547876707135497 0.5720232397985618 -0.05390676800212768 0.17302752842857483 +20 ENSG0000010000 Tgd 6603 T G chr20:6603:T:G -459334 0.39579274423103183 0.8789576316736196 0.3810275083419574 0.0502416845485871 +20 ENSG0000010000 Tgd 7786 A C chr20:7786:A:C 357091 0.7936520599056404 0.31094929784794634 0.6856931372228146 0.8583765484503407 +20 ENSG0000010000 Tgd 1610 C G chr20:1610:C:G 311630 0.8258233317797505 0.26941998100876363 -0.16645454458923448 0.6459092566162166 +20 ENSG0000010000 Tgd 3080 G T chr20:3080:G:T 457803 0.8239694342551407 0.740944798920008 0.5189865904525133 0.8673217815796754 +20 ENSG0000010000 Tgd 921 T A chr20:921:T:A -173764 0.7095693983643895 0.4033851410124437 0.561032859255304 0.5247619308714067 +20 ENSG0000010000 Tgd 9318 A T chr20:9318:A:T -297873 0.8751805561254168 0.20072677610052136 -0.8847449682728907 0.03403797346347728 +20 ENSG0000010000 Tgd 829 C T chr20:829:C:T -212714 0.36835192757477075 0.4642184637868879 -0.20611544496700462 0.9231504948045982 +20 ENSG0000010000 Tgd 501 T C chr20:501:T:C 12530 0.5940435934521513 0.17758369416386166 0.7409615438369257 0.5872933681740043 +20 ENSG0000010000 Tgd 5731 C T chr20:5731:C:T 378343 0.8944919203121954 0.7489611344849333 0.37770107523190855 0.2857843070583272 +20 ENSG0000010000 Tgd 6334 A T chr20:6334:A:T 395296 0.5722580610203007 0.9649176092022551 0.7142223748766046 0.6477325118697206 +20 ENSG0000010000 Tgd 3388 C G chr20:3388:C:G 38214 0.020052357499524387 0.7803036642606433 0.5351454568237026 0.009889088083975726 +20 ENSG0000010000 Tgd 2168 T A chr20:2168:T:A -265361 0.2523904413606515 0.8050855691954864 -0.38908060323088645 0.9670574189250083 +20 ENSG0000010000 Tgd 4512 C G chr20:4512:C:G -235761 0.21820905407293145 0.30214509127435196 0.04127579665647163 0.6239824900906934 +20 ENSG0000010000 Tgd 9577 C A chr20:9577:C:A 5139 0.06383705389710992 0.9883609658217671 0.2811894912293116 0.8616301086515787 +20 ENSG0000010000 Tgd 4279 C T chr20:4279:C:T -342788 0.5172935855796514 0.24030207767849443 -0.886450651207122 0.8574580446672542 +20 ENSG0000010000 Tgd 9831 G C chr20:9831:G:C 213824 0.13992950857641695 0.0254552711203736 -0.005254343189759592 0.2963090286043796 +20 ENSG0000010000 Tgd 6858 A T chr20:6858:A:T -140164 0.7265498765809035 0.2223631939762689 0.06927020308842624 0.7851121582408208 +20 ENSG0000010000 Tgd 5874 C T chr20:5874:C:T 381473 0.65761468467485 0.55824804440987 -0.4124318942784808 0.4713100918890251 +20 ENSG0000010000 Tgd 4238 T C chr20:4238:T:C 186224 0.0892998220194392 0.3552833961198324 0.4884198586856161 0.3077781860608763 +20 ENSG0000010000 Tgd 5429 C G chr20:5429:C:G 392562 0.11778147124153793 0.05367695440645037 0.2687934873040707 0.5807327953380099 +20 ENSG0000010000 Tgd 1167 G T chr20:1167:G:T 24788 0.11981593718750583 0.6806977643196971 0.05967700925999497 0.41369414675986693 +20 ENSG0000010000 Tgd 2471 C G chr20:2471:C:G 97062 0.892845123310543 0.9866492558834808 -0.713551695400723 0.862531549393779 +20 ENSG0000010000 Tgd 2955 A G chr20:2955:A:G -151213 0.6310327722626952 0.17682426656346073 0.268997938305342 0.005708787922569855 +20 ENSG0000010000 Tgd 4482 T G chr20:4482:T:G 323353 0.7635691671054993 0.0880413437590446 0.22895947745012357 0.6338540531618916 +20 ENSG0000010000 Tgd 6610 G A chr20:6610:G:A -460443 0.5337826028422582 0.7306590704105899 0.9001372309636639 0.8921143858052113 +20 ENSG0000010000 Tgd 8701 T A chr20:8701:T:A 209621 0.004123833974353341 0.733603240913325 -0.5474685774218331 0.8771081501245903 +20 ENSG0000010000 Tgd 5114 T A chr20:5114:T:A -97819 0.5033364786853692 0.30611509209141274 -0.8694259550594714 0.04667263338643345 +20 ENSG0000010000 Tgd 4765 G C chr20:4765:G:C -45270 0.8879740438370417 0.9954724098279284 -0.31453432148488014 0.9014823923683799 +20 ENSG0000010000 Tgd 5886 G A chr20:5886:G:A -260487 0.22432136332369457 0.9848795244932604 -0.5776195416737107 0.02289135879355027 +20 ENSG0000010000 Tgd 8268 T A chr20:8268:T:A -115602 0.7111100900958506 0.7921271550458925 -0.24961513464832108 0.640680764187376 +20 ENSG0000010000 Tgd 8762 G A chr20:8762:G:A 73867 0.25273829306957374 0.7018682148540548 -0.5890101686836478 0.6860542885190325 +20 ENSG0000010000 Tgd 153 C G chr20:153:C:G 193805 0.10097984718146147 0.5203092341868366 0.2455955536012997 0.7010256198572096 +20 ENSG0000010000 Tgd 6863 C A chr20:6863:C:A 322880 0.10626370830639498 0.1986466617062822 -0.600501227707283 0.2637309216981181 +20 ENSG0000010000 Tgd 8572 T C chr20:8572:T:C 237606 0.409756230528289 0.16037359863076883 0.09627752745680063 0.9104462708345524 +20 ENSG0000010000 Tgd 7876 C T chr20:7876:C:T -497129 0.012749401268609795 0.0890028395271304 -0.7791381651873566 0.5745786124270625 +20 ENSG0000010000 Tgd 8096 T A chr20:8096:T:A 317392 0.5117053469646589 0.7235636168984789 -0.7974190428140853 0.2566362106479142 +20 ENSG0000010000 Tgd 3788 G C chr20:3788:G:C -223045 0.4642773572361484 0.09980891505761746 -0.6505963821092182 0.04040507544872489 +20 ENSG0000010000 Tgd 4761 G A chr20:4761:G:A -400387 0.8512459006771743 0.890292011543282 -0.9806553445458603 0.13925604823001972 +20 ENSG0000010000 Tgd 2794 G C chr20:2794:G:C 421148 0.7330679453384229 0.3726221532744488 -0.3145545544792798 0.11471816790384595 +20 ENSG0000010000 Tgd 6558 G C chr20:6558:G:C 376303 0.38571548975931425 0.850671578036584 0.5997981938979002 0.6491976373883914 +20 ENSG0000010000 Tgd 2733 A T chr20:2733:A:T 229987 0.7264111120898007 0.9815691705231888 0.6886996948628932 0.10460939263263108 +20 ENSG0000010000 Tgd 9679 T G chr20:9679:T:G 317012 0.3585989148270966 0.02881622957122154 0.36892826676294566 0.8386979400705646 +20 ENSG0000010000 Tgd 2141 A G chr20:2141:A:G -37906 0.04597232537967 0.26161286722848986 -0.3715241102522582 0.7048636083041425 +20 ENSG0000010000 Tgd 8599 T C chr20:8599:T:C 44315 0.523103175224674 0.7005801842975543 -0.8095157230966106 0.6620515495831171 +20 ENSG0000010000 Tgd 4073 G C chr20:4073:G:C 195951 0.6762955683574412 0.3848766174067143 0.6780660424595746 0.5587858924654857 +20 ENSG0000010000 Tgd 895 A T chr20:895:A:T 30126 0.8488455747760008 0.8518711514460662 0.7388312692255359 0.0757903772345078 +20 ENSG0000010000 Tgd 8056 C T chr20:8056:C:T -153032 0.9701450487834001 0.05035071452654394 -0.554586953662402 0.6436739975084286 +20 ENSG0000010000 Tgd 6608 T A chr20:6608:T:A -18605 0.44418887645945904 0.5730349305875494 -0.8239602765949188 0.49895769002751295 +20 ENSG0000010000 Tgd 5179 A G chr20:5179:A:G 281439 0.6533730031383718 0.10264332148015243 -0.1753229046489011 0.5575738803934283 +20 ENSG0000010000 Tgd 3 A C chr20:3:A:C 433348 0.5083377403194649 0.20685124884989836 0.3429487415583121 0.9504047748633723 +20 ENSG0000010000 Tgd 5954 A T chr20:5954:A:T 385331 0.45445998260358433 0.5601508451060682 0.2395159393541686 0.4736605474124953 +20 ENSG0000010000 Tgd 5953 G A chr20:5953:G:A -397830 0.7593199510791171 0.22174710782019003 -0.3172857708463226 0.8300540017487668 +20 ENSG0000010000 Tgd 4784 C A chr20:4784:C:A -451999 0.8968771186780584 0.49242214218116687 0.6436773198374526 0.7427683794858868 +20 ENSG0000010000 Tgd 6705 A C chr20:6705:A:C 140524 0.19592146715181613 0.12074580736619422 0.7043887435331417 0.21637391486457702 +20 ENSG0000010000 Tgd 3123 C A chr20:3123:C:A 293928 0.41447034512833025 0.9266265305373107 0.67493247497293 0.5892222967900035 +20 ENSG0000010000 Tgd 7382 G T chr20:7382:G:T 23059 0.004337627666922916 0.7362139303130776 0.10645265780848678 0.43337756947411066 +20 ENSG0000010000 Tgd 9587 G T chr20:9587:G:T 225423 0.5785543857041766 0.7304946617427778 -0.7432364358968444 0.3880181736414453 +20 ENSG0000010000 Tgd 9840 C G chr20:9840:C:G -60999 0.979500760205043 0.9159102416970992 0.5247493125235854 0.2743222840761551 +20 ENSG0000010000 Tgd 5618 C G chr20:5618:C:G 343890 0.1333718310160935 0.4127454728076193 0.4000285697942503 0.7486784390120381 +20 ENSG0000010000 Tgd 4898 C T chr20:4898:C:T -289353 0.20971269625550193 0.7143845356298945 0.37322259463807295 0.9212705726526778 +20 ENSG0000010000 Tgd 2174 T C chr20:2174:T:C 244858 0.11540525228362541 0.3522378024628774 -0.03926015521874637 0.5710675560588462 +20 ENSG0000010000 Tgd 6840 C G chr20:6840:C:G 347568 0.012770515104606583 0.10647046584838726 -0.2382593729298308 0.05401193450826344 +20 ENSG0000010000 Tgd 928 T C chr20:928:T:C 286626 0.7855321925948217 0.9835323936240042 0.3667806573295742 0.14728196175055527 +20 ENSG0000010000 Tgd 1017 C T chr20:1017:C:T 290200 0.5411720874332366 0.3586824373455808 -0.09481099095225343 0.6164927249265263 +20 ENSG0000010000 Tgd 9206 T G chr20:9206:T:G -250864 0.5109223036788938 0.7968336477787923 0.39225699436126127 0.6932431391390343 +20 ENSG0000010000 Tgd 770 G C chr20:770:G:C 78944 0.05380219230774963 0.743669966245749 -0.5938255545413242 0.8689811113561985 +20 ENSG0000010000 Tgd 7260 T C chr20:7260:T:C 291787 0.5883853401736552 0.7384500324978454 -0.6070618364789078 0.7251896061921531 +20 ENSG0000010000 Tgd 3171 C G chr20:3171:C:G -313956 0.9834533235628817 0.07446899404359286 0.9249504979520309 0.7353444065401926 +20 ENSG0000010000 Tgd 1956 G A chr20:1956:G:A -50677 0.2791122463092105 0.26423959530939556 -0.6781423004867726 0.84616818189443 +20 ENSG0000010000 Tgd 93 C G chr20:93:C:G 244163 0.9374944504708476 0.039940589321429854 0.8572564769183102 0.5972834516823633 +20 ENSG0000010000 Tgd 4935 G C chr20:4935:G:C -423579 0.7840314485705014 0.3178590053721895 -0.5600759691448851 0.1846852284378236 +20 ENSG0000010000 Tgd 1118 T G chr20:1118:T:G 69460 0.5370359525339087 0.09194555393906645 -0.5576038377970944 0.21414045637600973 +20 ENSG0000010000 Tgd 5438 C T chr20:5438:C:T 496470 0.7526556895545169 0.5304988956068246 0.9932621652086775 0.8238647125242771 +20 ENSG0000010000 Tgd 145 A C chr20:145:A:C -32685 0.2403478764332566 0.6422643558211706 0.8372145983745409 0.24458333670301674 +20 ENSG0000010000 Tgd 654 C G chr20:654:C:G 460424 0.7962065856530344 0.11337402750459258 -0.48681888669375617 0.7242516327615541 +20 ENSG0000010000 Tgd 405 C G chr20:405:C:G 10451 0.043851660910501744 0.8982816089058533 -0.6149752241326458 0.5143808054273061 +20 ENSG0000010000 Tgd 1573 T A chr20:1573:T:A 157386 0.06547182210371993 0.6703351261430567 0.5471645327385533 0.8650859048569186 +20 ENSG0000010000 Tgd 6951 A T chr20:6951:A:T 63876 0.828748670985869 0.8786372317092412 0.48275006972561374 0.43580252491619126 +20 ENSG0000010000 Tgd 1182 T A chr20:1182:T:A -18468 0.7168682838359131 0.03788631474614812 -0.8535039416809669 0.1788141713918788 +20 ENSG0000010000 Tgd 4128 A T chr20:4128:A:T 455238 0.25864795899117565 0.38803260364477077 0.26043452925157573 0.4335920096046316 +20 ENSG0000010000 Tgd 277 G A chr20:277:G:A 60814 0.0058989274607802455 0.7202856810267967 -0.8735248184806021 0.7462050800101637 +20 ENSG0000010000 Tgd 746 A C chr20:746:A:C 473128 0.5028369509140814 0.28983659883508006 0.37175731809959855 0.6069592753456438 +20 ENSG0000010000 Tgd 4613 G A chr20:4613:G:A -2988 0.15632347414991077 0.2198657254605103 0.4935078232138239 0.7969736666060024 +20 ENSG0000010000 Tgd 8942 C T chr20:8942:C:T -187466 0.6772890455050625 0.9141689163846178 0.5900342444649185 0.7295952520392288 +20 ENSG0000010000 Tgd 6114 A T chr20:6114:A:T -370779 0.041773140467925574 0.5727185949433958 -0.2118365982599253 0.5479779247420461 +20 ENSG0000010000 Tgd 1395 C T chr20:1395:C:T 284645 0.741430483039814 0.7259373466957483 -0.5765261141560303 0.9057224023139892 +20 ENSG0000010000 Tgd 8398 C T chr20:8398:C:T -379810 0.18135798477365006 0.7996600536055314 0.7045022555349514 0.8515363347030488 +20 ENSG0000010000 Tgd 8993 G A chr20:8993:G:A -195229 0.6716852491152492 0.25068761481495494 -0.605164815104168 0.5810150577552855 +20 ENSG0000010000 Tgd 5421 C T chr20:5421:C:T 203904 0.6554729806969527 0.1000450572754229 0.23903155430866585 0.9002184722520788 +20 ENSG0000010000 Tgd 5207 T C chr20:5207:T:C 346934 0.3163331594963291 0.4283073929595911 -0.9903362346706572 0.24692896340693862 +20 ENSG0000010000 Tgd 3630 G C chr20:3630:G:C 380919 0.3594859997503893 0.6795801798475741 -0.3368740994053212 0.4804740165128225 +20 ENSG0000010000 Tgd 7297 G A chr20:7297:G:A -315692 0.6455516040818964 0.08197369308615465 -0.4387681207252496 0.8266172295500461 +20 ENSG0000010000 Tgd 8825 T C chr20:8825:T:C 269177 0.8863358320788955 0.07646237855721538 -0.8492000864132467 0.01961166457636412 +20 ENSG0000010000 Tgd 8310 A G chr20:8310:A:G 306564 0.590036311840718 0.9063035773981832 0.10318799705231663 0.5439258545942004 +20 ENSG0000010000 Tgd 8843 G T chr20:8843:G:T -116412 0.39249834584673227 0.8914375437210861 0.1792015095535937 0.8573069899805498 +20 ENSG0000010000 Tgd 2194 G A chr20:2194:G:A -83941 0.36386555807417087 0.010591683258700968 -0.5222383909228172 0.964036268060904 +20 ENSG0000010000 Tgd 2718 T G chr20:2718:T:G -333044 0.17914518390862078 0.9487118316129783 0.31882661390595346 0.9677678242776755 +20 ENSG0000010000 Tgd 7922 C A chr20:7922:C:A -270552 0.761472377834038 0.23174990760431557 -0.4712857697988275 0.23478465018246786 +20 ENSG0000010000 Tgd 7696 G A chr20:7696:G:A -458157 0.9805897820631023 0.3240711100639776 0.4074725056952446 0.5218515312294171 +20 ENSG0000010000 Tgd 4481 C T chr20:4481:C:T -105044 0.6536753131338843 0.36529677799104765 0.3066730931136996 0.8356335986089679 +20 ENSG0000010000 Tgd 8466 C G chr20:8466:C:G 451312 0.22289925453343817 0.405842202550903 0.6344735304671438 0.3456872907308839 +20 ENSG0000010000 Tgd 7899 A T chr20:7899:A:T -38733 0.16560582242899213 0.07708822574124685 0.2869540047766195 0.212305587031619 +20 ENSG0000010000 Tgd 3063 T C chr20:3063:T:C 131264 0.7173027084540954 0.11833022282354266 -0.5393073348013508 0.8113614567435871 +20 ENSG0000010000 Tgd 1857 G T chr20:1857:G:T 119489 0.16124625986262575 0.8333649963952542 -0.9551079236914173 0.044101187003830214 +20 ENSG0000010000 Tgd 9397 A T chr20:9397:A:T -441373 0.16634136630788177 0.922446870655101 0.03328138527629276 0.40605086014984665 +20 ENSG0000010000 Tgd 9235 A C chr20:9235:A:C 493267 0.08574850273574453 0.44920336161945673 0.9855516474159576 0.8674350965931023 +20 ENSG0000010000 Tgd 2795 T G chr20:2795:T:G 130025 0.14271213706296726 0.5826461376283554 0.534980225293102 0.6235885271727226 +20 ENSG0000010000 Tgd 8370 C T chr20:8370:C:T 259364 0.685591163804168 0.9223519448449473 0.19306672499471889 0.06977405414420344 +20 ENSG0000010000 Tgd 6197 G T chr20:6197:G:T -386156 0.01656262727341462 0.5227113430171585 0.8186784461790251 0.6846834633676351 +20 ENSG0000010000 Tgd 2451 A T chr20:2451:A:T -1015 0.9016082183625412 0.5998137968706828 0.7555052754859362 0.5318985202224991 +20 ENSG0000010000 Tgd 1926 A G chr20:1926:A:G 191423 0.13032884077716433 0.6034746508247105 0.6550435573041469 0.8970719838946841 +20 ENSG0000010000 Tgd 7070 G C chr20:7070:G:C 417319 0.043438283336481476 0.5298165189397056 -0.5410274872418996 0.802497895811806 +20 ENSG0000010000 Tgd 6247 C A chr20:6247:C:A -53843 0.13388310562460137 0.47714123700454003 -0.5349742187546886 0.85919419405411 +20 ENSG0000010000 Tgd 4642 G C chr20:4642:G:C -301798 0.0054694541480304615 0.7436456813620216 -0.985771841138793 0.5230180891581682 +20 ENSG0000010000 Tgd 8516 A G chr20:8516:A:G 186341 0.20541869616334685 0.8042871528558561 -0.18230984565213637 0.10747663323300921 +20 ENSG0000010000 Tgd 6981 G C chr20:6981:G:C 141603 0.27556054287998877 0.6806057050634484 0.5099438012196669 0.4138149301376405 +20 ENSG0000010000 Tgd 9136 G T chr20:9136:G:T -111804 0.5590938296534966 0.4837601576281908 0.9770165280499024 0.5780735019371803 +20 ENSG0000010000 Tgd 6523 T A chr20:6523:T:A 284140 0.229771304477713 0.7831092603453356 0.8984903568296896 0.10117833893182634 +20 ENSG0000010000 Tgd 8329 G C chr20:8329:G:C 339756 0.550576214596818 0.6970574087244603 0.41357986706573957 0.16157727112408402 +20 ENSG0000010000 Tgd 87 A T chr20:87:A:T -5420 0.9258617877978491 0.435377434552764 -0.8718390872613788 0.2225484743748925 +20 ENSG0000010000 Tgd 1312 A G chr20:1312:A:G 475893 0.9844481006312732 0.6139655907167139 0.04201108644111784 0.7118942258772722 +20 ENSG0000010000 Tgd 9789 A T chr20:9789:A:T 171394 0.49436837761828334 0.010710397375428893 0.7011352726352842 0.9308277088784127 +20 ENSG0000010000 Tgd 8490 C T chr20:8490:C:T -464759 0.7839594453537084 0.5105478503988208 0.39689946519838215 0.6155747957178459 +20 ENSG0000010000 Tgd 591 C T chr20:591:C:T 186837 0.00028727185462340543 0.15744476085039083 0.9936342876544126 0.7798932060974408 +20 ENSG0000010000 Tgd 5786 T A chr20:5786:T:A 272722 0.7036219244347302 0.9191774211091239 0.09918530709287188 0.7264125709975886 +20 ENSG0000010000 Tgd 9161 C T chr20:9161:C:T 135818 0.9630571394750862 0.4547590086587804 -0.19208706058700797 0.005646800114560104 +20 ENSG0000010000 Tgd 2868 G A chr20:2868:G:A 85766 0.07238597052670392 0.29425182446812004 0.8940309303553251 0.803139300329785 +20 ENSG0000010000 Tgd 4223 C G chr20:4223:C:G -104603 0.5631686038049302 0.7699671927338335 0.5149465700933449 0.9612774865763127 +20 ENSG0000010000 Tgd 7518 G A chr20:7518:G:A 5382 0.1162683014409226 0.06755426066125358 0.26732359511637704 0.9942038353321101 +20 ENSG0000010000 Tgd 3768 C G chr20:3768:C:G -129752 0.5165042172048383 0.009723191714424928 0.6643540898464573 0.24900935175271544 +20 ENSG0000010000 Tgd 1524 G C chr20:1524:G:C -420279 0.5545515040412264 0.17848574725207278 -0.3722544408807469 0.21934756765083913 +20 ENSG0000010000 Tgd 9400 C T chr20:9400:C:T 493125 0.7461562580101736 0.9302552633727152 -0.6196650043279033 0.7373751356934523 +20 ENSG0000010000 Tgd 3848 T C chr20:3848:T:C -283177 0.22920753212844247 0.8349404800660567 0.6726694199233785 0.3566713459703294 +20 ENSG0000010000 Tgd 1748 G A chr20:1748:G:A 301368 0.8570893372705127 0.9579930904676253 0.6960211915119301 0.37182533884828395 +20 ENSG0000010000 Tgd 5168 G C chr20:5168:G:C 14646 0.18287186312969528 0.7642623254359276 0.022267271284261536 0.3984816183736226 +20 ENSG0000010000 Tgd 9449 T A chr20:9449:T:A 51273 0.799269917779981 0.47832007661204345 0.08153589118365412 0.5029727369095509 +20 ENSG0000010000 Tgd 6451 T G chr20:6451:T:G -373785 0.6982445680961396 0.46007059004643003 0.3784210981192977 0.012808158631838474 +20 ENSG0000010000 Tgd 3453 G A chr20:3453:G:A -158756 0.3616023258326805 0.8618420232810137 -0.6256951160943003 0.2635861856110544 +20 ENSG0000010000 Tgd 4414 G C chr20:4414:G:C -116301 0.1839136741963775 0.42394288041094297 -0.16181411295067338 0.7524435676182607 +20 ENSG0000010000 Tgd 5982 G C chr20:5982:G:C -27377 0.17988922872699586 0.13113916649872392 0.15178545841592417 0.22933818275016893 +20 ENSG0000010000 Tgd 1637 C T chr20:1637:C:T 82316 0.4322187517308349 0.380883382231468 -0.7083125293249273 0.9591887728259225 +20 ENSG0000010000 Tgd 2451 G A chr20:2451:G:A -314814 0.4215206690102653 0.13447168466122272 0.7865408189503835 0.6310213325060156 +20 ENSG0000010000 Tgd 8749 C G chr20:8749:C:G -185392 0.2509740334908548 0.8585019824492522 -0.9045813918351844 0.09987582449505204 +20 ENSG0000010000 Tgd 2677 A T chr20:2677:A:T 353350 0.25428968277975483 0.8389717089374528 -0.8073962263784586 0.744848627241864 +20 ENSG0000010000 Tgd 4257 A G chr20:4257:A:G -372874 0.3510904898298426 0.6795858514541131 0.21115206478473691 0.5772769026705514 +20 ENSG0000010000 Tgd 8822 T C chr20:8822:T:C -127642 0.3250902866810026 0.5104445255361031 0.5494887342531407 0.44748318696575473 +20 ENSG0000010000 Tgd 1285 G C chr20:1285:G:C -13721 0.6317121904834689 0.14484833827806742 -0.6648489290389323 0.8079094268131114 +20 ENSG0000010000 Tgd 5528 T C chr20:5528:T:C -260697 0.3134820633894073 0.6530130974304403 0.42086697023320774 0.6057795880511376 +20 ENSG0000010000 Tgd 6480 C G chr20:6480:C:G 318910 0.8628064836470025 0.3631648402504287 0.1738395470520211 0.9655605067896721 +20 ENSG0000010000 Tgd 6783 A T chr20:6783:A:T 263124 0.234627192184497 0.2516470100018183 0.48775068969572954 0.7499899971782018 +20 ENSG0000010000 Tgd 3451 T G chr20:3451:T:G -391987 0.09555371898258025 0.9367936617038471 -0.05362840669700897 0.05477161278082835 +20 ENSG0000010000 Tgd 6505 C T chr20:6505:C:T -411594 0.6548326755433498 0.8854713170963988 -0.3812586929000028 0.24814912279587706 +20 ENSG0000010000 Tgd 4656 G T chr20:4656:G:T -362346 0.5267423379310799 0.17060798427888224 -0.9296900382109117 0.35748440152040445 +20 ENSG0000010000 Tgd 5329 C G chr20:5329:C:G -358322 0.9695422645545462 0.6976228769070474 -0.6459267200405758 0.5979866146377241 +20 ENSG0000010000 Tgd 9241 G C chr20:9241:G:C 453075 0.3471683001641309 0.5396681221360596 0.609415532492906 0.4424184452709579 +20 ENSG0000010000 Tgd 5993 G C chr20:5993:G:C -336719 0.30357291557308896 9.234639492805563e-05 0.6307595783217763 0.8480985418942879 +20 ENSG0000010000 Tgd 5635 C G chr20:5635:C:G 61091 0.0083171105963733 0.9220883957440529 0.8939150237362488 0.47759000338100566 +20 ENSG0000010000 Tgd 150 G C chr20:150:G:C 126003 0.23121539351915854 0.007217985005767535 -0.25271224694593286 0.41232413319706845 +20 ENSG0000010000 Tgd 9185 T C chr20:9185:T:C -416943 0.42223938275369266 0.23956181493856055 0.5290765881532291 0.9100444490358456 +20 ENSG0000010000 Tgd 4455 G T chr20:4455:G:T 394940 0.06846395270829775 0.13662403292652436 -0.7792872989640727 0.45588766963118077 +20 ENSG0000010000 Tgd 7419 C G chr20:7419:C:G -303089 0.3206437231555238 0.15214930511736913 0.9394324352587871 0.023108754729864345 +20 ENSG0000010000 Tgd 1676 T G chr20:1676:T:G 262427 0.008204089349586496 0.0901969831487811 -0.9705503062370486 0.2179708970976691 +20 ENSG0000010000 Tgd 6886 C G chr20:6886:C:G -110562 0.46368446720342926 0.7914247142652953 -0.3395027059283393 0.8437027529688105 +20 ENSG0000010000 Tgd 2394 A C chr20:2394:A:C 313331 0.3924217750980309 0.5431919505458085 -0.6367925227851825 0.8958032793380152 +20 ENSG0000010000 Tgd 4098 G A chr20:4098:G:A -372115 0.9745985028754597 0.7146825212907967 -0.23040420157871666 0.9749972419106809 +20 ENSG0000010000 Tgd 4050 A T chr20:4050:A:T -16780 0.735322779200941 0.09396030397071775 0.332015767427025 0.20923868492508468 +20 ENSG0000010000 Tgd 6376 T A chr20:6376:T:A 280900 0.9374209236322338 0.5209262529175096 -0.49337451932982224 0.6388814920299818 +20 ENSG0000010000 Tgd 3256 C A chr20:3256:C:A 405610 0.6666947842969614 0.97327406043506 -0.5280683244331337 0.4347274889215005 +20 ENSG0000010000 Tgd 247 T C chr20:247:T:C 113099 0.11964959201073866 0.7891437801948885 -0.9821402882213157 0.04295137565207431 +20 ENSG0000010000 Tgd 7787 T C chr20:7787:T:C 308239 0.08947990274967443 0.1576984561973751 -0.817196895391574 0.6190262135795032 +20 ENSG0000010000 Tgd 984 A C chr20:984:A:C 175885 0.1539184354344616 0.5363533257802295 -0.7852166872348272 0.48835503904105687 +20 ENSG0000010000 Tgd 5190 C G chr20:5190:C:G 268804 0.19296529905015847 0.6892499802840422 -0.2836650054991372 0.1355974415871913 +20 ENSG0000010000 Tgd 647 C G chr20:647:C:G -301006 0.5667017339663708 0.5436205442820837 -0.35263824861642123 0.46892632639444715 +20 ENSG0000010000 Tgd 9809 T A chr20:9809:T:A 56937 0.15502547807532696 0.29567266121073477 -0.47330146220913605 0.36774559429753495 +20 ENSG0000010000 Tgd 12 G T chr20:12:G:T 425821 0.018719856588055195 0.8568292883342146 0.5520331355958776 0.2395477716578051 +20 ENSG0000010000 Tgd 1038 G T chr20:1038:G:T 49526 0.6832241825576808 0.7657340955098555 -0.6917369721377009 0.2838459544500518 +20 ENSG0000010000 Tgd 6715 C A chr20:6715:C:A -399068 0.5232005391932355 0.06667984309626562 0.6703867157965828 0.13064449205592385 +20 ENSG0000010000 Tgd 513 T A chr20:513:T:A 8947 0.1916166402306675 0.03181714989999063 0.28350333625524526 0.3892102206890533 +20 ENSG0000010000 Tgd 8027 C A chr20:8027:C:A -115850 0.22072278414632096 0.7178451945697811 -0.9738277803329971 0.9211141741538744 +20 ENSG0000010000 Tgd 8052 A G chr20:8052:A:G 339930 0.6389167164318277 0.3609260511250785 0.4869548818207361 0.8905401793907377 +20 ENSG0000010000 Tgd 8668 C A chr20:8668:C:A 490488 0.21590006322105781 0.5194852731907311 -0.7975497584764373 0.2317869853088959 +20 ENSG0000010000 Tgd 6314 G A chr20:6314:G:A 303506 0.638624299888042 0.35796336587140376 -0.08255881514325125 0.6655771124187702 +20 ENSG0000010000 Tgd 1706 G C chr20:1706:G:C 189472 0.1581764558993315 0.9984335720532814 -0.1139756600034243 0.35297175119506186 +20 ENSG0000010000 Tgd 5164 C T chr20:5164:C:T 90500 0.5456262395823608 0.3750630748697237 0.1004774112425284 0.7448337701546776 +20 ENSG0000010000 Tgd 5899 G A chr20:5899:G:A 261594 0.03466290222820989 0.2844821706098528 -0.9673951042054689 0.1359506236345961 +20 ENSG0000010000 Tgd 4946 A C chr20:4946:A:C -267335 0.21482281279355597 0.31490467504934494 0.5430461439779388 0.9434045583384443 +20 ENSG0000010000 Tgd 4522 T A chr20:4522:T:A -460431 0.4603698056612592 0.15610710634595293 -0.4700236414807606 0.88973572713564 +20 ENSG0000010000 Tgd 4094 T C chr20:4094:T:C 350472 0.3003024316721046 0.5704871594890821 0.13812987384023967 0.2182198429445303 +20 ENSG0000010000 Tgd 1265 C G chr20:1265:C:G -318699 0.4882763983734342 0.8990240967988602 0.4056957896982498 0.8196957495715319 +20 ENSG0000010000 Tgd 1563 C A chr20:1563:C:A 266288 0.8083411721608318 0.3815461104994817 0.5602438160169527 0.9219496250236824 +20 ENSG0000010000 Tgd 5479 C G chr20:5479:C:G -63246 0.9302460839437775 0.12054052851935104 0.5407801155256877 0.7479309786120534 +20 ENSG0000010000 Tgd 9869 A G chr20:9869:A:G -443243 0.30478339287924283 0.04118225216356319 0.07985945887733825 0.15043043914813395 +20 ENSG0000010000 Tgd 8232 A G chr20:8232:A:G -32738 0.7528402030105307 0.5752548538500767 -0.8198340949105378 0.4325037344805392 +20 ENSG0000010000 Tgd 6461 C A chr20:6461:C:A -1031 0.5714405905106293 0.049311098070088044 -0.20161740090611624 0.08599390848076716 +20 ENSG0000010000 Tgd 8222 G T chr20:8222:G:T 299049 0.13487076372595497 0.5592961773135403 -0.024277800391334425 0.6525961905401897 +20 ENSG0000010000 Tgd 3213 A C chr20:3213:A:C 314504 0.43006573113360724 0.6847379723499571 0.15203647449008595 0.11341734153088781 +20 ENSG0000010000 Tgd 6777 G C chr20:6777:G:C -134773 0.1904897415692982 0.34452490951029313 0.31081971562216903 0.7699116107710751 +20 ENSG0000010000 Tgd 2774 C G chr20:2774:C:G 153453 0.14581847519027757 0.044877550931373245 0.6363438402636288 0.20048552839215 +20 ENSG0000010000 Tgd 6125 T A chr20:6125:T:A -382170 0.7395816300402434 0.24304830989942627 0.24200488517775676 0.14852940078738028 +20 ENSG0000010000 Tgd 4714 A C chr20:4714:A:C 227497 0.8042807736342995 0.30511805005417436 -0.057619392532883396 0.33254484234601644 +20 ENSG0000010000 Tgd 8815 C G chr20:8815:C:G 153306 0.7299235835097888 0.1413474209239418 0.3975104640165057 0.019370124043748167 +20 ENSG0000010000 Tgd 9552 A C chr20:9552:A:C -321407 0.06011004957566812 0.2006960570006705 0.3930533769423481 0.27201016993099564 +20 ENSG0000010000 Tgd 7618 G C chr20:7618:G:C 195186 0.8520829447572587 0.6601003733293648 0.7285645471199069 0.02005924561025998 +20 ENSG0000010000 Tgd 6333 T G chr20:6333:T:G 33243 0.9766119398898542 0.09960371184253736 -0.36908806138244055 0.8669059727825916 +20 ENSG0000010000 Tgd 8710 A T chr20:8710:A:T -291465 0.5006508228688789 0.4579862621477807 0.852699946052867 0.022466969756131185 +20 ENSG0000010000 Tgd 4054 T A chr20:4054:T:A -136375 0.6843113552921495 0.35537813324653333 -0.3953475767939574 0.9959984168355616 +20 ENSG0000010000 Tgd 8213 C A chr20:8213:C:A 156190 0.25767936467138874 0.3871705896437323 0.9999036016294156 0.9903712248462172 +20 ENSG0000010000 Tgd 9093 C T chr20:9093:C:T -340923 0.3417861528484174 0.39284659666517197 -0.7254786478311568 0.7301597742574282 +20 ENSG0000010000 Tgd 8532 T G chr20:8532:T:G -247964 0.5728985529597785 0.4264649970124451 -0.3752344711164328 0.6057635159861702 +20 ENSG0000010000 Tgd 7360 T C chr20:7360:T:C 221978 0.7051363877851007 0.5238054835018717 -0.7294950123121695 0.9956901144317767 +20 ENSG0000010000 Tgd 2379 T C chr20:2379:T:C -428892 0.5573402980935688 0.9486015641647615 -0.7632254185656426 0.31827999160202575 +20 ENSG0000010000 Tgd 2385 A C chr20:2385:A:C 422885 0.9728960351201903 0.9611961872223895 -0.3933037900476981 0.7458641202586498 +20 ENSG0000010000 Tgd 4486 A T chr20:4486:A:T -306280 0.026198221463318738 0.9859555930791913 0.23389301101658644 0.6059989067426028 +20 ENSG0000010000 Tgd 3784 A C chr20:3784:A:C -416664 0.6881412847327161 0.4766022200441854 0.004649174900922537 0.6051070478431487 +20 ENSG0000010000 Tgd 6127 T G chr20:6127:T:G 15318 0.47384692085916336 0.16378637547239527 -0.547453879829801 0.4091805710179679 +20 ENSG0000010000 Tgd 246 C G chr20:246:C:G -266635 0.7423666616628996 0.9882434174629566 0.5155531794512584 0.06707018791065447 +20 ENSG0000010000 Tgd 7198 G C chr20:7198:G:C 408879 0.4575449294417121 0.24678384086158633 -0.19026646351494314 0.04278444877506804 +20 ENSG0000010000 Tgd 6233 C G chr20:6233:C:G 141209 0.9391391332631398 0.5719344511166646 0.072318770367362 0.6417524306618212 +20 ENSG0000010000 Tgd 631 A G chr20:631:A:G -20906 0.8270101016593498 0.042415916009097776 0.9916727430480963 0.5191839499349242 +20 ENSG0000010000 Tgd 6482 A G chr20:6482:A:G 41198 0.7651598724026124 0.9625923115707594 -0.6202993200543618 0.44011432084174335 +20 ENSG0000010000 Tgd 4990 C G chr20:4990:C:G -325427 0.4224621824504414 0.6131342792438925 -0.8909066663689471 0.5174526806158719 +20 ENSG0000010000 Tgd 2331 C G chr20:2331:C:G -473878 0.17887857894361558 0.590315475289654 0.42526878261260537 0.20273007270444846 +20 ENSG0000010000 Tgd 7450 A C chr20:7450:A:C -160183 0.6917174283309014 0.9071624630054067 0.5929724449514451 0.7186563449988445 +20 ENSG0000010000 Tgd 2025 G C chr20:2025:G:C -410550 0.5238173060661488 0.3840873742615717 0.5821331884740504 0.5121547850330208 +20 ENSG0000010000 Tgd 2620 A T chr20:2620:A:T 456566 0.33519313905754367 0.8713054035569007 0.7253449581576843 0.16296197227351158 +20 ENSG0000010000 Tgd 2370 T A chr20:2370:T:A -60037 0.30806220553456465 0.730161747102666 0.9219322271087502 0.2894917569073021 +20 ENSG0000010000 Tgd 2961 A T chr20:2961:A:T -287295 0.0035328985941434077 0.7653958071255011 -0.975584470351895 0.4981299797933969 +20 ENSG0000010000 Tgd 8170 A G chr20:8170:A:G -250567 0.21687384388493236 0.6594706213154792 -0.09252303227556702 0.442433486136239 +20 ENSG0000010000 Tgd 9851 A T chr20:9851:A:T 425020 0.5473416095831464 0.6197660388695853 0.11509729653777745 0.825427252198979 +20 ENSG0000010000 Tgd 802 A C chr20:802:A:C -461496 0.14537441621593594 0.03243209173527761 0.15618543085477388 0.6036821784238748 +20 ENSG0000010000 Tgd 5425 A G chr20:5425:A:G -313094 0.16133522743054096 0.2843805448047053 0.32184922235479374 0.7001469692094178 +20 ENSG0000010000 Tgd 9377 T G chr20:9377:T:G 285734 0.5789662924422967 0.9314798193860057 -0.8137474243564609 0.2999951871149169 +20 ENSG0000010000 Tgd 6039 G A chr20:6039:G:A 295284 0.42732383939109464 0.5504710828134854 -0.4143345732865209 0.135411243288973 +20 ENSG0000010000 Tgd 4497 C G chr20:4497:C:G 50131 0.20984536927811426 0.2090509803001116 -0.8836308254405525 0.5717957084402351 +20 ENSG0000010000 Tgd 8667 A G chr20:8667:A:G 259246 0.6886542782543451 0.9338916747881832 0.9725568846882229 0.2879001165004562 +20 ENSG0000010000 Tgd 9976 C T chr20:9976:C:T 144129 0.5626343376666078 0.5197058001844937 0.2637152149936721 0.4930119492647974 +20 ENSG0000010000 Tgd 2948 T C chr20:2948:T:C -297043 0.001580917225831202 0.023986797518176006 0.2509214847793064 0.1188077981973506 +20 ENSG0000010000 Tgd 3397 A C chr20:3397:A:C -133366 0.5604155049178265 0.6375035435880566 -0.9774054640439405 0.20198595179116013 +20 ENSG0000010000 Tgd 4615 C A chr20:4615:C:A -177278 0.3002839945755126 0.5499935993844556 0.5340652019699106 0.11472292618565219 +20 ENSG0000010000 Tgd 5461 C G chr20:5461:C:G 259584 0.5689215407967071 0.9601128252529902 0.6640855398122829 0.19482156431812275 +20 ENSG0000010000 Tgd 5537 A T chr20:5537:A:T 4884 0.15538628866672877 0.4606179363433891 0.7304487010384728 0.8960326728356968 +20 ENSG0000010000 Tgd 7578 G A chr20:7578:G:A 375671 0.521073224390624 0.5649426409972023 0.3563952492997473 0.5556220310952483 +20 ENSG0000010000 Tgd 307 T C chr20:307:T:C 338373 0.9161864510776807 0.7957827996730472 -0.8675739173648762 0.15015560122713115 +20 ENSG0000010000 Tgd 511 C G chr20:511:C:G 156944 0.5342731762111617 0.16596948780850795 0.21137817784497548 0.18819153123793508 +20 ENSG0000010000 Tgd 1915 A C chr20:1915:A:C -66027 0.08679778499196789 0.8770487326207924 -0.2568328462257039 0.8296280114485027 +20 ENSG0000010000 Tgd 4959 T C chr20:4959:T:C -316486 0.11223127226692198 0.7849439832374083 0.5555807829215884 0.9134404923208915 +20 ENSG0000010000 Tgd 7271 A G chr20:7271:A:G 448914 0.5000543084299398 0.19021167859521426 0.8472735357801904 0.7327086256891877 +20 ENSG0000010000 Tgd 8580 T A chr20:8580:T:A 362074 0.9822734738739121 0.5161466201895273 0.98544068832274 0.20598192293082224 +20 ENSG0000010000 Tgd 599 C A chr20:599:C:A 220426 0.8481240242294041 0.8718750930359653 -0.33342049320227063 0.8892966901219906 +20 ENSG0000010000 Tgd 1690 C A chr20:1690:C:A 105615 0.7584938206683315 0.6388508520434467 -0.5803086262810175 0.20135495674128154 +20 ENSG0000010000 Tgd 4696 G A chr20:4696:G:A -214102 0.14932072279971842 0.27363688584015067 -0.9694865650192195 0.6233220177148739 +20 ENSG0000010000 Tgd 8423 A T chr20:8423:A:T 68882 0.35031813792411726 0.31848491185197303 -0.7168863424170344 0.7046493424415502 +20 ENSG0000010000 Tgd 4642 A C chr20:4642:A:C 143052 0.8922431047166801 0.5405771020326587 -0.8985476325441302 0.02996369351643942 +20 ENSG0000010000 Tgd 827 A G chr20:827:A:G -443587 0.08611958046604495 0.39191676064568004 0.40935518735828036 0.8913846186933179 +20 ENSG0000010000 Tgd 7305 C T chr20:7305:C:T 247528 0.7584025462781657 0.8092998231462011 -0.8429087851392942 0.9228612073733448 +20 ENSG0000010000 Tgd 7630 T A chr20:7630:T:A 352336 0.8023504981375413 0.6985994090756469 -0.8054740063014005 0.31108129282141844 +20 ENSG0000010000 Tgd 7626 G T chr20:7626:G:T 493471 0.22379445391686015 0.8610962770558958 0.2338841744967215 0.9129487490660391 +20 ENSG0000010000 Tgd 6424 T C chr20:6424:T:C 327094 0.860791592913895 0.32476108858945263 -0.024986534859774645 0.06629983361705413 +20 ENSG0000010000 Tgd 1850 C G chr20:1850:C:G -16354 0.8457662624925489 0.28225736892179776 -0.3027691155010428 0.575103579798837 +20 ENSG0000010000 Tgd 8323 A G chr20:8323:A:G 357266 0.7142730861660672 0.10698129479490015 0.11229972018974133 0.07185306596486647 +20 ENSG0000010000 Tgd 4950 G T chr20:4950:G:T 151034 0.24369106104931992 0.15902028958418757 -0.035250687840335804 0.06699387471656086 +20 ENSG0000010000 Tgd 3412 C T chr20:3412:C:T -318507 0.6626122569263369 0.07789440258865832 0.8617265181527856 0.5746141025193887 +20 ENSG0000010000 Tgd 7973 A G chr20:7973:A:G -158817 0.5550877012137614 0.8220230523140447 -0.6476519955987377 0.95592756293258 +20 ENSG0000010000 Tgd 1141 A G chr20:1141:A:G -156688 0.4942951473965429 0.6601647590211199 -0.8189339903352892 0.81721655633135 +20 ENSG0000010000 Tgd 9516 A T chr20:9516:A:T 192984 0.14921643177400834 0.5312558210753147 -0.22003467953842648 0.5783534834810541 +20 ENSG0000010000 Tgd 3206 T C chr20:3206:T:C -185705 0.5702764078553516 0.9132042652335682 -0.39089973392335153 0.9433899641986176 +20 ENSG0000010000 Tgd 7123 C A chr20:7123:C:A 111033 0.008119252409717004 0.9864216484906068 -0.1916051678711661 0.1284281413603773 +20 ENSG0000010000 Tgd 4820 A C chr20:4820:A:C 444846 0.5488851366035604 0.05312731117638425 0.40670824885413426 0.8209325303563292 +20 ENSG0000010000 Tgd 5886 A C chr20:5886:A:C 407730 0.031184742117234765 0.43171550111637913 0.18032774916691063 0.6255890891165224 +20 ENSG0000010000 Tgd 6272 G T chr20:6272:G:T 194668 0.17341010626309672 0.1390688656883451 0.11084315753869789 0.8434843430560645 +20 ENSG0000010000 Tgd 5903 G T chr20:5903:G:T -197517 0.9974560430104709 0.6700660819228675 -0.7314451037108489 0.07267425054118667 +20 ENSG0000010000 Tgd 258 T G chr20:258:T:G 189886 0.43673511575888857 0.9902176420075874 -0.8306731114205679 0.6426006566817736 +20 ENSG0000010000 Tgd 6814 T G chr20:6814:T:G 34160 0.42412468457259256 0.8200714249167276 -0.23057056433994738 0.22651517749283642 +20 ENSG0000010000 Tgd 6960 A G chr20:6960:A:G 387938 0.7309133800622073 0.7121299989650309 -0.46149910374227465 0.9266378871993727 +20 ENSG0000010000 Tgd 9443 C A chr20:9443:C:A -460296 0.5681495777015994 0.7048825425548747 -0.7736712607701306 0.48205137578231094 +20 ENSG0000010000 Tgd 1312 T C chr20:1312:T:C -12479 0.5169495499002531 0.5233567944907804 0.2201412184304945 0.2459860728083485 +20 ENSG0000010000 Tgd 1280 C A chr20:1280:C:A 447477 0.34354617100233775 0.7785271332471325 -0.06226237931795775 0.5131504472803252 +20 ENSG0000010000 Tgd 7688 C G chr20:7688:C:G -129943 0.9605813024771251 0.798223222006991 -0.4215831135584689 0.036290913934678565 +20 ENSG0000010000 Tgd 9792 A G chr20:9792:A:G 106224 0.16907924095436921 0.05161988479137325 0.9807296587788046 0.8090868838998876 +20 ENSG0000010000 Tgd 448 C G chr20:448:C:G -413482 0.12682133544680552 0.07686225959245296 0.5675256442703127 0.2527989234880076 +20 ENSG0000010000 Tgd 4604 G C chr20:4604:G:C 347082 0.1753993649874075 0.7825277052877461 -0.527608238385342 0.18162838167378775 +20 ENSG0000010000 Tgd 8641 A C chr20:8641:A:C -411499 0.9673456336935627 0.595544091864987 0.6434475355468734 0.8377766053859318 +20 ENSG0000010000 Tgd 6766 G T chr20:6766:G:T 192759 0.44018500839173114 0.6375746664947514 -0.5782865050769241 0.7346267498283922 +20 ENSG0000010000 Tgd 5654 A C chr20:5654:A:C 292182 0.819531009465414 0.05252319699228103 -0.07197014393292678 0.47675571039368025 +20 ENSG0000010000 Tgd 7804 T G chr20:7804:T:G 216712 0.7056078045820481 0.47458958076406377 -0.7097003380888385 0.870407458113876 +20 ENSG0000010000 Tgd 195 C G chr20:195:C:G -99440 0.678493405250375 0.9617627228070305 0.3657526218275837 0.04197659741540955 +20 ENSG0000010000 Tgd 8705 C G chr20:8705:C:G 140140 0.9180420164172792 0.8583556731983318 -0.33006518676391083 0.2678207279035005 +20 ENSG0000010000 Tgd 1611 C G chr20:1611:C:G -16493 0.7731510153061979 0.7490909117594134 0.46862691151931646 0.5891355668136983 +20 ENSG0000010000 Tgd 3194 C T chr20:3194:C:T -171513 0.5476125554038433 0.6728018597399902 0.6633789996497623 0.012949449612479728 +20 ENSG0000010000 Tgd 1601 A G chr20:1601:A:G -131409 0.2194163257274825 0.2832970190934546 -0.6138409371071791 0.024676772384180323 +20 ENSG0000010000 Tgd 1507 A T chr20:1507:A:T 496659 0.5993849757170892 0.12179013124164262 0.915590675472872 0.08729998768556395 +20 ENSG0000010000 Tgd 9908 T G chr20:9908:T:G 188279 0.7638577662400693 0.6479058382367253 0.6064001316899881 0.18558384776194112 +20 ENSG0000010000 Tgd 1817 T C chr20:1817:T:C -191123 0.4669555772876578 0.9361820599117441 0.2775610156870447 0.9227726954538533 +20 ENSG0000010000 Tgd 4529 G C chr20:4529:G:C -230164 0.1619660316462166 0.07399706004029116 0.5542119005678203 0.38341620344073946 +20 ENSG0000010000 Tgd 5451 A C chr20:5451:A:C 352283 0.2646648524547329 0.4405748327776676 -0.01655642718938033 0.9286577119340631 +20 ENSG0000010000 Tgd 6433 T G chr20:6433:T:G -386303 0.1438726003515135 0.768707323307198 -0.563227003604676 0.6436948288019259 +20 ENSG0000010000 Tgd 7235 C A chr20:7235:C:A -463446 0.07291950337895992 0.5713445598449196 -0.4988072994763082 0.44643617027063676 +20 ENSG0000010000 Tgd 8155 T A chr20:8155:T:A 478209 0.03783563274596502 0.3904838209333753 -0.6967850521198631 0.3305010384523341 +20 ENSG0000010000 Tgd 6412 A G chr20:6412:A:G 1365 0.4360576674633677 0.8440491536838368 0.5618740739267416 0.7855963233860551 +20 ENSG0000010000 Tgd 6299 G A chr20:6299:G:A 94798 0.53530407648565 0.9916013803997511 -0.333120574327771 0.30352524840991335 +20 ENSG0000010000 Tgd 905 A C chr20:905:A:C 60596 0.8533420783350283 0.3400627902184187 0.6823631742542884 0.7606926278005658 +20 ENSG0000010000 Tgd 4751 A G chr20:4751:A:G 192829 0.19100316091530278 0.6958822786070757 0.7929213957006933 0.6309864403914939 +20 ENSG0000010000 Tgd 5887 G A chr20:5887:G:A 428214 0.6327912691085319 0.7353241830279268 -0.7201140964672226 0.19389962619050763 +20 ENSG0000010000 Tgd 9715 T G chr20:9715:T:G -92348 0.06299263084485507 0.5405520472184392 -0.38453824073546916 0.5344061067178018 +20 ENSG0000010000 Tgd 7362 C A chr20:7362:C:A -145877 0.7877785319165288 0.042814533453493175 -0.763625782554177 0.8072966021015948 +20 ENSG0000010000 Tgd 8571 G T chr20:8571:G:T 277048 0.5793457123114589 0.9248158117535223 -0.9262446651539249 0.14244888175581252 +20 ENSG0000010000 Tgd 313 G A chr20:313:G:A -245529 0.7012968111692847 0.13053773354265985 -0.655501982083001 0.05090803938923537 +20 ENSG0000010000 Tgd 5036 A G chr20:5036:A:G 140916 0.17068938788288945 0.5910424892899215 0.6356003555278538 0.10722486905802407 +20 ENSG0000010000 Tgd 8146 T A chr20:8146:T:A 343530 0.20264114011981682 0.33734311022997665 0.6717918959586731 0.73819047460496 +20 ENSG0000010000 Tgd 6587 C A chr20:6587:C:A 217318 0.575967010452485 0.13732940198175514 0.6728541845782456 0.7933085682766036 +20 ENSG0000010000 Tgd 747 T C chr20:747:T:C -433708 0.12074548955182252 0.1412368026193237 -0.1696913515321785 0.696599489894192 +20 ENSG0000010000 Tgd 9068 T G chr20:9068:T:G -244521 0.9256755305974618 0.040698894361934634 -0.8000642986438828 0.8475193435368121 +20 ENSG0000010000 Tgd 6163 T A chr20:6163:T:A 422355 0.48696747482361347 0.0063495785536169524 -0.6411742877045727 0.09005209878112751 +20 ENSG0000010000 Tgd 9728 C G chr20:9728:C:G 227191 0.8074118032473379 0.7725627085269426 0.3847166616751614 0.20695405837107272 +20 ENSG0000010000 Tgd 4440 A T chr20:4440:A:T 252037 0.4998876349035636 0.9502980641128211 0.2543833080900251 0.7828004472918701 +20 ENSG0000010000 Tgd 5700 G A chr20:5700:G:A 84801 0.23563900732921705 0.11750782271179194 0.06039804185616182 0.09658817110435677 +20 ENSG0000010000 Tgd 5930 T G chr20:5930:T:G 307750 0.6264642451653417 0.20810870287140149 -0.8938619614583405 0.11356644324076437 +20 ENSG0000010000 Tgd 2445 T G chr20:2445:T:G -236408 0.3342946292222987 0.805153674558398 0.5168160416654888 0.04427416517076398 +20 ENSG0000010000 Tgd 860 A G chr20:860:A:G 39915 0.11606508546217897 0.8950791749007987 0.44280616111786486 0.593113955603406 +20 ENSG0000010000 Tgd 5341 G T chr20:5341:G:T 283377 0.6768525458751079 0.3256849589203539 0.5579505579193362 0.32680609248246456 +20 ENSG0000010000 Tgd 1607 T G chr20:1607:T:G 412141 0.1999558312858073 0.8913651497711447 -0.8529405672700665 0.5855071653345473 +20 ENSG0000010000 Tgd 891 G T chr20:891:G:T -273335 0.9278871164428707 0.45499087257728543 -0.2253393922226865 0.13726820996614134 +20 ENSG0000010000 Tgd 3182 T C chr20:3182:T:C -366609 0.032094595523257 0.5686658327255526 -0.43879169022289677 0.11199816126972216 +20 ENSG0000010000 Tgd 7628 T C chr20:7628:T:C -269467 0.8864089719590657 0.6036359828471252 0.5790939300442546 0.6383612146661235 +20 ENSG0000010000 Tgd 2785 T A chr20:2785:T:A -68306 0.8569737637174784 0.48921339856236457 0.9913286747998387 0.5919892904238068 +20 ENSG0000010000 Tgd 7582 C A chr20:7582:C:A 265479 0.428110366584203 0.8725984710950715 -0.5043371121988305 0.4348144712365237 +20 ENSG0000010000 Tgd 3644 T A chr20:3644:T:A -61935 0.9801840412931456 0.040058679813694154 -0.05869473914092338 0.768837784444631 +20 ENSG0000010000 Tgd 551 G A chr20:551:G:A -25581 0.49528504342221835 0.0830915239340585 0.5061573835078326 0.6934666791636832 +20 ENSG0000010000 Tgd 6663 T A chr20:6663:T:A -483297 0.4797829513924986 0.30483660222443065 0.4066089758170073 0.8580641891197146 +20 ENSG0000010000 Tgd 9563 A G chr20:9563:A:G -13712 0.7718350078063004 0.8741990380222714 -0.18927925549528402 0.7900688540762681 +20 ENSG0000010000 Tgd 6069 G A chr20:6069:G:A 402176 0.6273050238989188 0.38487926791186955 0.38150127728143524 0.5313894066265334 +20 ENSG0000010000 Tgd 4860 G C chr20:4860:G:C 231963 0.9460954935290011 0.542435106450538 0.5889575065247181 0.7879041522963383 +20 ENSG0000010000 Tgd 1327 C A chr20:1327:C:A 39740 0.9453222297877379 0.6746529665886649 0.7759558119112637 0.11185557718256138 +20 ENSG0000010000 Tgd 5990 G A chr20:5990:G:A -116671 0.3664329959099546 0.6481726583748344 0.409747318431823 0.5611974503444715 +20 ENSG0000010000 Tgd 3355 T C chr20:3355:T:C -249776 0.5396338262674039 0.6490384003407765 0.4747601291410315 0.7525248630310539 +20 ENSG0000010000 Tgd 3438 T C chr20:3438:T:C -130156 0.8979330380809146 0.5035659721510614 -0.15414174978218487 0.05540553699661643 +20 ENSG0000010000 Tgd 7967 A G chr20:7967:A:G 244305 0.5319044789545855 0.8253790179852802 0.7989023967424682 0.4525264042416983 +20 ENSG0000010000 Tgd 6032 A T chr20:6032:A:T 435228 0.8839789812108436 0.08730875015385742 -0.2186349943586312 0.17963300868931642 +20 ENSG0000010000 Tgd 1261 A T chr20:1261:A:T -210654 0.11202458066554444 0.1479540429735834 -0.699003862217171 0.20505190231775447 +20 ENSG0000010000 Tgd 372 C G chr20:372:C:G 215551 0.5414349580684413 0.13202736879814347 -0.3065995064358418 0.44441619200983296 +20 ENSG0000010000 Tgd 352 C T chr20:352:C:T -433993 0.022036618529213126 0.8019891026044492 0.6698950372256145 0.5201008624734532 +20 ENSG0000010000 Tgd 5504 G C chr20:5504:G:C 187614 0.646051226458135 0.3263064137559264 0.18671451011084517 0.6971667171391551 +20 ENSG0000010000 Tgd 8987 C T chr20:8987:C:T 441916 0.7893482618517801 0.17173712543597597 -0.47998508473065593 0.4847588694805682 +20 ENSG0000010000 Tgd 4721 A T chr20:4721:A:T -129726 0.28438203376476856 0.9562138554927935 0.23726045972304988 0.16162909259721903 +20 ENSG0000010000 Tgd 8771 C T chr20:8771:C:T -316123 0.8393316768714126 0.6928592689686354 0.33271193198050963 0.15433131536911018 +20 ENSG0000010000 Tgd 3898 C T chr20:3898:C:T -37695 0.26040719724947314 0.18449658308293937 0.12497448484799834 0.035654399565515804 +20 ENSG0000010000 Tgd 5193 C T chr20:5193:C:T -108971 0.4484290967871739 0.9754656788900316 0.06728591474234702 0.12236853341395806 +20 ENSG0000010000 Tgd 409 T G chr20:409:T:G 472880 0.32021793094317064 0.004294305817411526 0.47698996284820994 0.9756254351206244 +20 ENSG0000010000 Tgd 4749 T G chr20:4749:T:G -144864 0.6891469814800889 0.7316405212803276 0.8003489381086961 0.14028387016304078 +20 ENSG0000010000 Tgd 9027 A C chr20:9027:A:C -474000 0.40162992192448665 0.8408769162026405 -0.10805461768219549 0.09338865017175751 +20 ENSG0000010000 Tgd 902 C T chr20:902:C:T -476357 0.08358955039391136 0.8494513887573635 0.35412677633103384 0.9576660747698661 +20 ENSG0000010000 Tgd 8386 G T chr20:8386:G:T 14290 0.3177578121660044 0.6050778218474674 0.8868043282039106 0.9085385032676131 +20 ENSG0000010000 Tgd 5916 G T chr20:5916:G:T 250742 0.8538040699633991 0.3696299671092079 -0.25433769803954975 0.28536571523230736 +20 ENSG0000010000 Tgd 5757 C G chr20:5757:C:G 416771 0.5610330111354487 0.21569515561948227 0.7756097531947546 0.7417861488506539 +20 ENSG0000010000 Tgd 6810 G C chr20:6810:G:C -328254 0.805672785103326 0.970360673202005 -0.15233560310892003 0.8965323977304964 +20 ENSG0000010000 Tgd 2287 A T chr20:2287:A:T -282123 0.30323113854686257 0.9883824278974966 0.05060209313986208 0.3360813254196171 +20 ENSG0000010000 Tgd 9678 G A chr20:9678:G:A -493060 0.4094606387526243 0.9144104963043992 -0.17097197212438275 0.5562580311198371 +20 ENSG0000010000 Tgd 9305 T G chr20:9305:T:G -196476 0.5538669265105248 0.04223291443883781 0.6524966106115713 0.8347506164284277 +20 ENSG0000010000 Tgd 4980 T A chr20:4980:T:A 329653 0.0024466749580499547 0.2626770235610708 0.9120531922661543 0.8344088282803019 +20 ENSG0000010000 Tgd 7743 A C chr20:7743:A:C -62580 0.17937230685268712 0.9067931971538303 0.28957169122621806 0.02941414228257012 +20 ENSG0000010000 Tgd 4542 G A chr20:4542:G:A 127983 0.7455655735862218 0.5810657700932466 0.13114917928082503 0.8684775722746075 +20 ENSG0000010000 Tgd 7800 A C chr20:7800:A:C 37422 0.7329572705571628 0.017545080522299306 -0.4809256320767519 0.5820728424299648 +20 ENSG0000010000 Tgd 2395 C G chr20:2395:C:G 420982 0.6932830448113187 0.35738546522936854 -0.8942233432431468 0.3618022844947464 +20 ENSG0000010000 Tgd 5833 A C chr20:5833:A:C -194169 0.5296123298924157 0.9363170197369656 0.027732986119610503 0.7666759952411198 +20 ENSG0000010000 Tgd 3003 A T chr20:3003:A:T 70123 0.32260686064096633 0.3162104325504749 0.6899897707248799 0.8000773290378692 +20 ENSG0000010000 Tgd 4448 C A chr20:4448:C:A 60380 0.5800466414662403 0.8233148168304377 -0.9742046723224307 0.5186525755311276 +20 ENSG0000010000 Tgd 6112 C T chr20:6112:C:T -392608 0.21787621196027773 0.5033828930639735 0.6631471095743295 0.795311631300745 +20 ENSG0000010000 Tgd 9154 A G chr20:9154:A:G -17140 0.9160311600297714 0.11656565084192705 -0.7375356864421108 0.01836201983719097 +20 ENSG0000010000 Tgd 5706 T G chr20:5706:T:G 432945 0.9875817343417453 0.5231211093335564 0.9402229091829826 0.17303495246309777 +20 ENSG0000010000 Tgd 4992 C T chr20:4992:C:T -279966 0.13021825239888996 0.07860496211651757 0.3816362733099412 0.7842456933230941 +20 ENSG0000010000 Tgd 1274 A G chr20:1274:A:G 294122 0.43124747307983735 0.19635099252922372 -0.9344145686469201 0.6601290545013972 +20 ENSG0000010000 Tgd 9719 A G chr20:9719:A:G -375302 0.9085292984024619 0.04328149606471776 -0.3967083891095755 0.011262124365536221 +20 ENSG0000010000 Tgd 1582 A T chr20:1582:A:T 116146 0.9011748671533497 0.18478182457834957 -0.2969326670578254 0.09168853372641962 +20 ENSG0000010000 Tgd 4545 A T chr20:4545:A:T 250582 0.1915475201924428 0.2818567914647866 0.8033205830159464 0.5375893625268682 +20 ENSG0000010000 Tgd 1617 T G chr20:1617:T:G -115736 0.6981329067750317 0.18512577891100812 0.3470513963363726 0.10821718020489571 +20 ENSG0000010000 Tgd 5814 G A chr20:5814:G:A 298395 0.9846127503684183 0.12361540247426694 -0.7793676775734488 0.13677645753562592 +20 ENSG0000010000 Tgd 5919 C A chr20:5919:C:A -413757 0.32811540733063815 0.11572260696277847 -0.4327771148540711 0.6007891189190615 +20 ENSG0000010000 Tgd 5112 G T chr20:5112:G:T 80822 0.40728222050211815 0.9849623281908457 -0.1440766723635052 0.8569169757629896 +20 ENSG0000010000 Tgd 7794 C T chr20:7794:C:T -486594 0.9987233256858505 0.4916483735449275 -0.7896562308613992 0.43862029205366754 +20 ENSG0000010000 Tgd 6469 G A chr20:6469:G:A 277447 0.9252903155418308 0.9778533292466641 -0.8705791776819529 0.9752322866982766 +20 ENSG0000010000 Tgd 5549 T G chr20:5549:T:G -371275 0.23286963878653288 0.424704206922654 -0.0017797756415856014 0.7650521951897464 +20 ENSG0000010000 Tgd 9535 C G chr20:9535:C:G -126605 0.4758262832960263 0.6031654324392886 -0.1911128016185284 0.48504832640218065 +20 ENSG0000010000 Tgd 4570 T G chr20:4570:T:G -386716 0.12219006009913869 0.4893413819169534 -0.5383564140145329 0.9424606015717518 +20 ENSG0000010000 Tgd 487 A G chr20:487:A:G 211047 0.026748887986485226 0.17909568833286293 0.2091678482175523 0.3276289299471968 +20 ENSG0000010000 Tgd 4961 T C chr20:4961:T:C 194255 0.4978990442324456 0.5047947560374831 0.08487622951888496 0.8096721157939183 +20 ENSG0000010000 Tgd 8857 G A chr20:8857:G:A -97735 0.45011551912545555 0.8528742892767233 -0.11488770753657462 0.03694513780494726 +20 ENSG0000010000 Tgd 2898 C T chr20:2898:C:T 15353 0.43068111788100183 0.31245967533978214 -0.22183901835300146 0.7642471268644379 +20 ENSG0000010000 Tgd 9321 G T chr20:9321:G:T 31297 0.05573712580937751 0.2633909843466514 0.1820902373026423 0.3784199073562229 +20 ENSG0000010000 Tgd 5780 A T chr20:5780:A:T 377589 0.3664100941186903 0.8095534275625432 0.16793395618945106 0.7654288263354565 +20 ENSG0000010000 Tgd 5592 G A chr20:5592:G:A -51055 0.3451430275436157 0.35736608067102427 -0.2974614790611083 0.6615787658168722 +20 ENSG0000010000 Tgd 4057 T C chr20:4057:T:C 121314 0.0849417366861478 0.6879912619702535 0.7378799215691156 0.11535682520461575 +20 ENSG0000010000 Tgd 2782 A C chr20:2782:A:C -460807 0.460909386409579 0.8633685217982011 0.13609880976021005 0.901508435366686 +20 ENSG0000010000 Tgd 4369 A G chr20:4369:A:G 116551 0.02223645140055397 0.3165143309365033 0.14070708141179056 0.3230989473832108 +20 ENSG0000010000 Tgd 1602 G A chr20:1602:G:A 224423 0.6751112953268611 0.33596746248551745 0.00553704517270881 0.7651389966288221 +20 ENSG0000010000 Tgd 5564 T C chr20:5564:T:C -119017 0.9694277527629668 0.20175862682574763 0.2708884007831527 0.9741331566226665 +20 ENSG0000010000 Tgd 1235 T C chr20:1235:T:C -221965 0.04753136111289458 0.996227693360453 -0.19594529562289997 0.22666009105703014 +20 ENSG0000010000 Tgd 1507 A C chr20:1507:A:C -213357 0.06726977651140309 0.8011856714715335 -0.04946326573035287 0.21052941949642567 +20 ENSG0000010000 Tgd 1257 G C chr20:1257:G:C -290205 0.41431425066516514 0.25126479286673564 0.030738464791008724 0.6718886882117299 +20 ENSG0000010000 Tgd 8972 T A chr20:8972:T:A 158342 0.703331645699025 0.8627098067592005 0.15368659048085842 0.21373985221345276 +20 ENSG0000010000 Tgd 7657 C G chr20:7657:C:G 480036 0.5661164427296449 0.6267584715774779 0.04453917146694697 0.36491039448994544 +20 ENSG0000010000 Tgd 2421 C G chr20:2421:C:G -69811 0.31865318015356314 0.8302143805558815 -0.8711449409436065 0.20435448345632115 +20 ENSG0000010000 Tgd 6758 T C chr20:6758:T:C 220219 0.6012322696755068 0.40586593924822967 -0.772882846743431 0.19272409546879277 +20 ENSG0000010000 Tgd 4024 C G chr20:4024:C:G 8960 0.5598250105328344 0.43613291101171914 0.2938441024073306 0.03796673098794005 +20 ENSG0000010000 Tgd 2611 C T chr20:2611:C:T -469443 0.2583968474691348 0.8035381829572616 0.3173414252803639 0.17680923667288959 +20 ENSG0000010000 Tgd 692 G A chr20:692:G:A -441986 0.8595840029158106 0.08392954106557937 0.20319948044388236 0.8673046079689123 +20 ENSG0000010000 Tgd 6669 C A chr20:6669:C:A -83826 0.9431621420369332 0.7242344531621804 -0.7188796961897441 0.1128204315260231 +20 ENSG0000010000 Tgd 8197 A C chr20:8197:A:C 20566 0.8845648623276411 0.23807685524092104 -0.7554463330925871 0.806880558372266 +20 ENSG0000010000 Tgd 5396 G T chr20:5396:G:T 480942 0.42286899848288584 0.1442779087037892 -0.6496914891286398 0.9699535524641929 +20 ENSG0000010000 Tgd 7201 G C chr20:7201:G:C 404816 0.5894809443945095 0.49035858015321165 -0.25059003085467646 0.948762178576353 +20 ENSG0000010000 Tgd 5186 T C chr20:5186:T:C 422152 0.7842732514215431 0.1449115303382129 -0.049556438391339386 0.3683715493794083 +20 ENSG0000010000 Tgd 5050 A T chr20:5050:A:T -234729 0.5527279033116267 0.3092685016911406 0.9169672235938429 0.36349224332164176 +20 ENSG0000010000 Tgd 2000 T G chr20:2000:T:G -92659 0.007866106255271177 0.9607479676080909 0.8550148006974585 0.9180087666830282 +20 ENSG0000010000 Tgd 4930 A T chr20:4930:A:T -188130 0.21038649126452746 0.8902467277662994 0.8317816024846709 0.6317213499536154 +20 ENSG0000010000 Tgd 6657 A C chr20:6657:A:C 408533 0.08009455966351753 0.7794566820598797 -0.016616277827452564 0.7372050245445099 +20 ENSG0000010000 Tgd 5452 G A chr20:5452:G:A 364446 0.16034334673346717 0.2609700747306236 -0.8672655321381042 0.421449661579086 +20 ENSG0000010000 Tgd 8974 C G chr20:8974:C:G 228980 0.027350893333371262 0.052098822901940234 0.28318502282708313 0.6305261851769801 +20 ENSG0000010000 Tgd 2230 A G chr20:2230:A:G -290206 0.6282962732430364 0.3137218026504617 -0.8355358971531959 0.15866461700464748 +20 ENSG0000010000 Tgd 8461 T G chr20:8461:T:G 331145 0.9394182214096123 0.45148989914629956 0.7470116873856203 0.1343762919785022 +20 ENSG0000010000 Tgd 2843 T A chr20:2843:T:A -65369 0.367599563165674 0.3934941804140062 -0.2453599431401916 0.8348443723206004 +20 ENSG0000010000 Tgd 9346 T A chr20:9346:T:A 494164 0.02297009470397493 0.5585299853019914 0.22400631944279903 0.2294785385425235 +20 ENSG0000010000 Tgd 1458 G T chr20:1458:G:T -225501 0.7012611542033469 0.16875595636504115 -0.19793017777794542 0.4294744647502328 +20 ENSG0000010000 Tgd 4263 T A chr20:4263:T:A -114208 0.17012288382085783 0.5672428989212999 -0.9717701864453641 0.5263118626305727 +20 ENSG0000010000 Tgd 7434 G A chr20:7434:G:A -264612 0.7135637119646769 0.19054416526893014 0.7238734485717477 0.782339821487193 +20 ENSG0000010000 Tgd 4718 T G chr20:4718:T:G 397935 0.20660595297875095 0.21556659784322563 0.6481777769769317 0.7269813589715322 +20 ENSG0000010000 Tgd 3103 G T chr20:3103:G:T -71632 0.7924635346676622 0.028773116247303387 0.9522563258081593 0.23625013977335807 +20 ENSG0000010000 Tgd 7389 T C chr20:7389:T:C 111218 0.6842670861425665 0.45816411141856517 -0.9793595154750108 0.13407173108735698 +20 ENSG0000010000 Tgd 5297 G T chr20:5297:G:T 247986 0.3834954552982238 0.4232909510739453 0.19439188027718046 0.0739825626029382 +20 ENSG0000010000 Tgd 7716 C A chr20:7716:C:A -494379 0.25365688282655174 0.6196578769455676 -0.3949852887164971 0.39530211753838324 +20 ENSG0000010000 Tgd 6077 T A chr20:6077:T:A 108684 0.1793722231707845 0.1698664985876286 -0.01432034477104338 0.3398375591264579 +20 ENSG0000010000 Tgd 7670 T A chr20:7670:T:A -167269 0.7102555746616706 0.43292965845611486 -0.47918797855314543 0.31395633844374116 +20 ENSG0000010000 Tgd 2096 G C chr20:2096:G:C 284149 0.3605922082531231 0.4300860187629275 0.8055853527327832 0.2639531719335812 +20 ENSG0000010000 Tgd 4322 C G chr20:4322:C:G 436034 0.16498381879585167 0.7368692382765193 -0.01745044047124078 0.9501006471597663 +20 ENSG0000010000 Tgd 9105 G A chr20:9105:G:A -301904 0.14862080704098313 0.2298605455692211 -0.9282755036615205 0.26096373962157515 +20 ENSG0000010000 Tgd 7654 G A chr20:7654:G:A 438659 0.9272063411393074 0.040791708540317995 -0.28695976750823005 0.7093201131246512 +20 ENSG0000010000 Tgd 7950 A T chr20:7950:A:T -370340 0.349604301851823 0.2037337114525818 -0.43176710336424473 0.8351187058771156 +20 ENSG0000010000 Tgd 8336 C T chr20:8336:C:T 111893 0.9980045554908168 0.004125725671763725 0.5336952592549891 0.18138827833535198 +20 ENSG0000010000 Tgd 1259 T G chr20:1259:T:G 209790 0.0943052238774873 0.328657776310758 -0.4314374971194217 0.9813531408083347 +20 ENSG0000010000 Tgd 1999 G C chr20:1999:G:C 119014 0.9291484426797915 0.10606992123259007 -0.3529233313534339 0.029845627687738557 +20 ENSG0000010000 Tgd 7541 C A chr20:7541:C:A -154571 0.9697705138016268 0.6561727570173506 0.9017919369504153 0.32559055283271504 +20 ENSG0000010000 Tgd 9326 A C chr20:9326:A:C -161131 0.7981469709838556 0.7437999924326247 0.09431244361251867 0.6026892357245798 +20 ENSG0000010000 Tgd 1517 G C chr20:1517:G:C -313343 0.24008013282007945 0.77087748695549 -0.20216548309939641 0.02149152384321003 +20 ENSG0000010000 Tgd 3412 T G chr20:3412:T:G 317357 0.40239623401266245 0.6471680011790883 0.9088649102160975 0.15498052719594077 +20 ENSG0000010000 Tgd 4892 C T chr20:4892:C:T -123515 0.6655202962168417 0.832052874322659 0.025306451318729772 0.49013341279325606 +20 ENSG0000010000 Tgd 6359 G C chr20:6359:G:C 90408 0.6003407494952573 0.09022234943874652 -0.15492730124303167 0.36886779619942534 +20 ENSG0000010000 Tgd 3054 C G chr20:3054:C:G 209298 0.22423021232791696 0.6862365358593723 -0.6898605982859789 0.4958269315045433 +20 ENSG0000010000 Tgd 8597 A C chr20:8597:A:C -9037 0.43735551893102464 0.9072077110524824 -0.04477726965556661 0.1494579321161065 +20 ENSG0000010000 Tgd 2094 C T chr20:2094:C:T 48501 0.4277318067512037 0.5685356858948489 0.10198865944940616 0.9173847107667461 +20 ENSG0000010000 Tgd 8412 A G chr20:8412:A:G -66918 0.09448436248791581 0.6608552539371698 0.1369564207319134 0.2541269507341249 +20 ENSG0000010000 Tgd 4176 A G chr20:4176:A:G -311726 0.7861770926580438 0.842909823305587 -0.9094825672613001 0.416835310055901 +20 ENSG0000010000 Tgd 4877 C G chr20:4877:C:G 294143 0.6702598664905719 0.6238103941666637 -0.4698512205282692 0.966752907143487 +20 ENSG0000010000 Tgd 3067 A C chr20:3067:A:C 413955 0.6734087624127466 0.4337989206193089 -0.9641695617758175 0.3955389091488836 +20 ENSG0000010000 Tgd 218 T G chr20:218:T:G -17485 0.6918062299869328 0.868780520988383 0.9316076151169363 0.6022855526893249 +20 ENSG0000010000 Tgd 7975 G C chr20:7975:G:C -408108 0.12508948993022695 0.013875918021813649 -0.776174995065209 0.01686936126900019 +20 ENSG0000010000 Tgd 3084 A T chr20:3084:A:T 4487 0.6486232217040224 0.6497398260368422 -0.12842305239901397 0.6264330919782158 +20 ENSG0000010000 Tgd 8825 T A chr20:8825:T:A -184465 0.7697211464004632 0.14816564674667332 -0.15624155071650714 0.11734236073448788 +20 ENSG0000010000 Tgd 2498 G A chr20:2498:G:A 401561 0.44951627839525243 0.2426296487550319 -0.4103371863152019 0.8296213117614737 +20 ENSG0000010000 Tgd 6419 A C chr20:6419:A:C -491744 0.10266352169521054 0.8476295300803542 -0.13642409474422146 0.4162702199724886 +20 ENSG0000010000 Tgd 8122 C A chr20:8122:C:A 11177 0.3996803722240102 0.5133557214665359 0.44922837036095986 0.9353456729798707 +20 ENSG0000010000 Tgd 7994 T A chr20:7994:T:A 53971 0.01901965902749103 0.5764033519912521 0.10651137029395352 0.2685810219793343 +20 ENSG0000010000 Tgd 6835 G A chr20:6835:G:A 18823 0.6226966898066139 0.6461798127499528 -0.10334921333917335 0.4367937739848056 +20 ENSG0000010000 Tgd 2644 C T chr20:2644:C:T -7966 0.3438473898031613 0.23210311314192367 -0.5605953099182441 0.909161084013351 +20 ENSG0000010000 Tgd 5557 G T chr20:5557:G:T 426074 0.2933940419777855 0.7113851859448196 0.9196067365536253 0.8332476650495513 +20 ENSG0000010000 Tgd 3395 C A chr20:3395:C:A 199459 0.4828897649727505 0.17329110353800814 -0.6873718111850471 0.49269354922922565 +20 ENSG0000010000 Tgd 6816 G C chr20:6816:G:C -253880 0.2094329413535484 0.047049336129883046 -0.9637388086499759 0.8810252008776903 +20 ENSG0000010000 Tgd 5850 C G chr20:5850:C:G -380495 0.6175629215440918 0.12068803282068252 -0.5518087225203918 0.2585643188630727 +20 ENSG0000010000 Tgd 5576 C A chr20:5576:C:A 307503 0.8777136471645709 0.26749123555658527 -0.6976432524113634 0.690445446758136 +20 ENSG0000010000 Tgd 8445 A T chr20:8445:A:T 160525 0.11805935107819343 0.20538622819621688 -0.27672312919747033 0.7286209287854347 +20 ENSG0000010000 Tgd 7234 G A chr20:7234:G:A -338210 0.6470929709355302 0.3346075253126083 -0.7244550716432414 0.8487464966229232 +20 ENSG0000010000 Tgd 7195 G A chr20:7195:G:A -242768 0.8348133698787183 0.4736633326211577 -0.42648340009119035 0.1720905337046729 +20 ENSG0000010000 Tgd 4359 C G chr20:4359:C:G -121838 0.6294404019787554 0.2454512801141382 0.5064125173316474 0.5301206238068676 +20 ENSG0000010000 Tgd 3739 T G chr20:3739:T:G -66509 0.9180200577475824 0.8980652575101931 0.9036810823141108 0.5166391382501478 +20 ENSG0000010000 Tgd 5928 A G chr20:5928:A:G -347344 0.7701518610861056 0.7176257357466732 0.03469739770357072 0.07051160770426264 +20 ENSG0000010000 Tgd 5543 C G chr20:5543:C:G 309891 0.1643246817147156 0.061468328485386525 0.5183847701116462 0.6605159961029614 +20 ENSG0000010000 Tgd 2474 A C chr20:2474:A:C -60327 0.4020028180314812 0.6808706574200868 0.10722085645118895 0.3050186999501994 +20 ENSG0000010000 Tgd 5140 C A chr20:5140:C:A 367176 0.27978074476278214 0.5277917356073935 0.8409011832902105 0.7005947688187222 +20 ENSG0000010000 Tgd 7311 T G chr20:7311:T:G 231351 0.3452506131505585 0.8118310777959458 0.2975140125230804 0.7756249342419091 +20 ENSG0000010000 Tgd 4941 C G chr20:4941:C:G 260321 0.7188805396858767 0.8798756161779585 0.040939405440151067 0.541249434475928 +20 ENSG0000010000 Tgd 3502 A C chr20:3502:A:C 46660 0.3407088798064464 0.6356855046751152 -0.9531565155403134 0.8904290190771378 +20 ENSG0000010000 Tgd 8847 C T chr20:8847:C:T 372655 0.7741577871437526 0.7265092463995954 0.973909400482097 0.11133146433721616 +20 ENSG0000010000 Tgd 983 C A chr20:983:C:A -449949 0.7565599430424155 0.9413430327530935 -0.1025262281602457 0.5728628449300068 +20 ENSG0000010000 Tgd 86 G C chr20:86:G:C -252435 0.8053875621092175 0.9890000788986222 0.1311944531596767 0.8944445589974662 +20 ENSG0000010000 Tgd 8738 T C chr20:8738:T:C -186265 0.2845354949453649 0.7847892628243508 0.4297089364046711 0.6727613682361805 +20 ENSG0000010000 Tgd 6188 T A chr20:6188:T:A -156228 0.5164518250701505 0.19255526231857178 0.5570990199039507 0.454855281300022 +20 ENSG0000010000 Tgd 2402 A G chr20:2402:A:G 431669 0.1300633212644835 0.2147844019991464 -0.8438546155498294 0.6771456203142504 +20 ENSG0000010000 Tgd 6599 G C chr20:6599:G:C 112686 0.498827305707791 0.4234221949913485 -0.1198400901404344 0.9311045720567719 +20 ENSG0000010000 Tgd 8021 G T chr20:8021:G:T -348643 0.5057858908707199 0.48476440244280217 -0.08457439945064227 0.968063774725945 +20 ENSG0000010000 Tgd 8409 A T chr20:8409:A:T -22445 0.47335556173777116 0.7464963060381985 0.8881391221139832 0.3699627275748227 +20 ENSG0000010000 Tgd 1946 G A chr20:1946:G:A -373263 0.3695859653634187 0.28959057510109343 0.0455549978212193 0.11862447118085537 +20 ENSG0000010000 Tgd 4996 C G chr20:4996:C:G -470664 0.791203701070468 0.14213980573261153 0.17924848827357542 0.04960239553364978 +20 ENSG0000010000 Tgd 5000 C T chr20:5000:C:T -308030 0.8191250692282641 0.48879365624551285 -0.7553441889951036 0.34930029456687695 +20 ENSG0000010000 Tgd 733 C G chr20:733:C:G 444019 0.3378232477705877 0.3773056304099227 0.6689199763541442 0.8338497819982766 +20 ENSG0000010000 Tgd 2176 T G chr20:2176:T:G 298678 0.4499293913485165 0.4490747388376488 0.7326911051253102 0.32589107026327885 +20 ENSG0000010000 Tgd 6712 G T chr20:6712:G:T 443974 0.39539712920038306 0.5409944507913269 0.9161589841610764 0.8901531219456575 +20 ENSG0000010000 Tgd 407 C A chr20:407:C:A 175192 0.5593528232362273 0.19242673333859683 0.23740810963264591 0.5772787275899764 +20 ENSG0000010000 Tgd 867 T G chr20:867:T:G 27054 0.8968642802436952 0.12028317643891573 0.8723636199811016 0.18056365802447782 +20 ENSG0000010000 Tgd 311 C T chr20:311:C:T -242799 0.8296905510546095 0.8389174408290969 0.15910550123795075 0.08556329667653217 +20 ENSG0000010000 Tgd 8742 C G chr20:8742:C:G 117499 0.04498364397490795 0.861974335714048 -0.9534735032922543 0.43758040236925705 +20 ENSG0000010000 Tgd 6799 A C chr20:6799:A:C -99433 0.2571777931677184 0.1146446241422453 -0.8013327339026441 0.1689878366743503 +20 ENSG0000010000 Tgd 2360 T C chr20:2360:T:C 305625 0.08962856348028303 0.306794218362605 -0.18544713141607394 0.170021856940201 +20 ENSG0000010000 Tgd 5330 T A chr20:5330:T:A 247949 0.05850178225356584 0.38993971123355786 -0.3599170723190823 0.4134099891865105 +20 ENSG0000010000 Tgd 5312 C G chr20:5312:C:G 487315 0.8277413986586146 0.12096626350192807 -0.59488108397092 0.7523816052333087 +20 ENSG0000010000 Tgd 9602 T G chr20:9602:T:G 33328 0.7523899786503706 0.38504867963013834 -0.76983725623358 0.061571345925466016 +20 ENSG0000010000 Tgd 7616 G A chr20:7616:G:A 7690 0.028906437810464092 0.6335412951837514 0.8274701965772493 0.019604209683020225 +20 ENSG0000010000 Tgd 9078 A T chr20:9078:A:T 300040 0.5547074500586905 0.7852141866503011 -0.39077431606880375 0.4073391754965206 +20 ENSG0000010000 Tgd 1375 C T chr20:1375:C:T 320011 0.2451614852066012 0.9526126267295513 0.922704218499254 0.5555970959834028 +20 ENSG0000010000 Tgd 685 A G chr20:685:A:G 369659 0.6207299179527868 0.6530588490671053 -0.6652366518893402 0.061114855897227635 +20 ENSG0000010000 Tgd 7901 G C chr20:7901:G:C 383360 0.6322069407459656 0.5851591664603665 0.020656843204964526 0.046439245583525864 +20 ENSG0000010000 Tgd 8751 A C chr20:8751:A:C -405927 0.3953049011411466 0.12297696493937149 -0.7206994634110664 0.5569226024212124 +20 ENSG0000010000 Tgd 4579 G T chr20:4579:G:T 140098 0.5048202496574608 0.8020565533511633 0.7678632241800574 0.9454630575648889 +20 ENSG0000010000 Tgd 4283 G C chr20:4283:G:C -242126 0.6622770278380956 0.3216382514061764 -0.5787522128254274 0.9590336867340964 +20 ENSG0000010000 Tgd 5382 A T chr20:5382:A:T 177844 0.9222577810440027 0.6087867504099678 -0.9914415046357365 0.010569034375501343 +20 ENSG0000010000 Tgd 2844 G A chr20:2844:G:A 325549 0.876720291741917 0.651266471129083 0.07729865656714896 0.8926796208936852 +20 ENSG0000010000 Tgd 7294 A C chr20:7294:A:C 352262 0.3763764487763258 0.6013108742085527 -0.22649793062826062 0.83930664698927 +20 ENSG0000010000 Tgd 139 A G chr20:139:A:G -111523 0.9362478494121943 0.444577656756068 -0.5569584705957109 0.020761887994874776 +20 ENSG0000010000 Tgd 4607 C T chr20:4607:C:T -405664 0.8162808240461551 0.6252365581928083 0.6168289887578715 0.22192653285729647 +20 ENSG0000010000 Tgd 8091 C A chr20:8091:C:A -205606 0.4928378753699927 0.7040477000696063 0.21205392791459432 0.00812826474674562 +20 ENSG0000010000 Tgd 6490 A C chr20:6490:A:C 96746 0.5003256387562403 0.17047709637720276 -0.6124594858312844 0.7390760127167503 +20 ENSG0000010000 Tgd 9880 T A chr20:9880:T:A 116735 0.12824639488736866 0.06504932140880004 -0.4807510385876388 0.5703333873944244 +20 ENSG0000010000 Tgd 3735 C T chr20:3735:C:T 388843 0.6779787169629149 0.991951353623053 0.38597163077793195 0.5334085758242167 +20 ENSG0000010000 Tgd 4144 G A chr20:4144:G:A 483449 0.4271144765687457 0.6730997856190369 0.30006009417567836 0.854005951753412 +20 ENSG0000010000 Tgd 5293 C A chr20:5293:C:A 213213 0.5182952692105377 0.4955747154464709 0.03451382754775456 0.044421210005273125 +20 ENSG0000010000 Tgd 3679 A C chr20:3679:A:C 463003 0.4200620690912774 0.44886149701656375 -0.9896814317724276 0.19541353136577538 +20 ENSG0000010000 Tgd 1341 A T chr20:1341:A:T 223044 0.42382025687229397 0.07444036690142164 -0.500031676935005 0.16531709368449007 +20 ENSG0000010000 Tgd 5093 A G chr20:5093:A:G -47069 0.8080590741636121 0.5925307705791362 0.2525942166903734 0.3349682334189644 +20 ENSG0000010000 Tgd 4103 T A chr20:4103:T:A -3420 0.23835921256842207 0.34080196792272854 -0.8911342796439858 0.3342548665639412 +20 ENSG0000010000 Tgd 3879 A G chr20:3879:A:G 301215 0.09567074943593701 0.44645619078676746 -0.7503472553858952 0.9745510531934071 +20 ENSG0000010000 Tgd 547 G C chr20:547:G:C 433320 0.8476921446126973 0.06502821879570364 -0.7449284186660912 0.919196671974545 +20 ENSG0000010000 Tgd 7241 A C chr20:7241:A:C 140405 0.6261852117764874 0.0657902591066627 0.3551289149491481 0.5596987935539405 +20 ENSG0000010000 Tgd 4832 A G chr20:4832:A:G -255565 0.8645827442376006 0.7874748085418644 0.24801631287644121 0.45395783546966384 +20 ENSG0000010000 Tgd 7606 G A chr20:7606:G:A -143887 0.6509214262484375 0.6757761000315036 -0.9480558417130001 0.5176956796412577 +20 ENSG0000010000 Tgd 9631 T A chr20:9631:T:A -392323 0.0122885822890334 0.7132993941571151 0.18577299698317673 0.8409386829467186 +20 ENSG0000010000 Tgd 9392 T C chr20:9392:T:C -127346 0.42100700349658204 0.7246230365399337 -0.11075137278551761 0.24390932539504037 +20 ENSG0000010000 Tgd 723 A T chr20:723:A:T -173194 0.5845222952652582 0.5131257396917145 0.30340996018608846 0.3583858944540996 +20 ENSG0000010000 Tgd 9563 G C chr20:9563:G:C 132636 0.3429003156055803 0.3688299951722551 -0.9838363153088006 0.5868534725384349 +20 ENSG0000010000 Tgd 8309 A G chr20:8309:A:G -139483 0.19540712964915308 0.20037190348323275 0.8170004368016306 0.7854785432840539 +20 ENSG0000010000 Tgd 5596 T G chr20:5596:T:G 228531 0.6918410061443094 0.4674023881536893 0.3848276783696625 0.8521566736462141 +20 ENSG0000010000 Tgd 9275 G C chr20:9275:G:C -329838 0.10484789650367266 0.876105478325422 0.821086049708607 0.4964347426532691 +20 ENSG0000010000 Tgd 61 G T chr20:61:G:T -249371 0.48074620764394227 0.7683484103723482 0.6293053378390536 0.807464035953144 +20 ENSG0000010000 Tgd 6159 T G chr20:6159:T:G -306806 0.8260843231519911 0.006725388488301176 -0.9802158165912158 0.3585287781282333 +20 ENSG0000010000 Tgd 9089 A T chr20:9089:A:T -195309 0.4404081195175904 0.6313345773941754 0.8254175300230493 0.36054932752147995 +20 ENSG0000010000 Tgd 487 C T chr20:487:C:T -270420 0.8853822295516643 0.7188366739026049 -0.3203650139639649 0.5549504502022139 +20 ENSG0000010000 Tgd 2926 T A chr20:2926:T:A -315370 0.8428814207150682 0.9106489501982198 -0.9580124790751081 0.6777749266185334 +20 ENSG0000010000 Tgd 6209 A C chr20:6209:A:C 481586 0.21023737866485392 0.4562036785494531 -0.2607186912076509 0.37297790783083296 +20 ENSG0000010000 Tgd 2808 G A chr20:2808:G:A -375751 0.14443224581124714 0.9241554672330221 0.5897962330228257 0.19248961085842659 +20 ENSG0000010000 Tgd 757 T C chr20:757:T:C 327942 0.1485669190263793 0.247171648243509 0.2589182823242533 0.28079323320074856 +20 ENSG0000010000 Tgd 2072 G T chr20:2072:G:T 262627 0.08140770185489365 0.47066729360071724 0.32700439713726115 0.06580816792894972 +20 ENSG0000010000 Tgd 8334 G C chr20:8334:G:C 22807 0.5188923661728745 0.17899851740764916 0.42497374674497124 0.5259501954303322 +20 ENSG0000010000 Tgd 7919 C G chr20:7919:C:G 169102 0.9211852236883675 0.5839826215038989 -0.9267910241007866 0.22030675637714364 +20 ENSG0000010000 Tgd 3326 G T chr20:3326:G:T -84869 0.21859372635184993 0.42502285457185596 -0.2458340738509539 0.15805212694081214 +20 ENSG0000010000 Tgd 6130 C A chr20:6130:C:A -359145 0.7516227519812296 0.2950480166413285 0.037641441100462414 0.23094740063233862 +20 ENSG0000010000 Tgd 675 G C chr20:675:G:C -53200 0.4511512031223698 0.43250566280598024 -0.26497611694776335 0.4980455185897901 +20 ENSG0000010000 Tgd 4474 G A chr20:4474:G:A -311712 0.44168849463604687 0.2656248781483982 -0.8482231146232349 0.9015743715341097 +20 ENSG0000010000 Tgd 4826 A C chr20:4826:A:C 471616 0.22774159236557112 0.11858788185826441 -0.2795262182014975 0.5464800339274577 +20 ENSG0000010000 Tgd 5469 T C chr20:5469:T:C -237832 0.30271558273741106 0.8155647797024462 0.36707865961563924 0.27519009194859706 +20 ENSG0000010000 Tgd 9897 T C chr20:9897:T:C -491052 0.7700760908385675 0.2818452702634696 -0.3067352804075443 0.9968454928577491 +20 ENSG0000010000 Tgd 6648 A G chr20:6648:A:G 185864 0.5126469730531769 0.7611605372390811 -0.7014377137204093 0.3981077797662535 +20 ENSG0000010000 Tgd 3718 T G chr20:3718:T:G -254924 0.5158253504857692 0.7859746482418123 0.5152425984850275 0.7227878409965582 +20 ENSG0000010000 Tgd 7560 C A chr20:7560:C:A -171718 0.8458016677785407 0.4287929741302956 0.8838595553925821 0.418270176808351 +20 ENSG0000010000 Tgd 7188 G A chr20:7188:G:A -107099 0.13895022554329362 0.8737502107645991 -0.38885612870225317 0.7380672560533246 +20 ENSG0000010000 Tgd 8189 T G chr20:8189:T:G -53601 0.6857628058837815 0.4033687171551702 0.557286809243539 0.5380664023707625 +20 ENSG0000010000 Tgd 5343 C G chr20:5343:C:G -100159 0.2042046185485472 0.39063614654324386 0.06898116151144862 0.18915033946411963 +20 ENSG0000010000 Tgd 1780 C G chr20:1780:C:G 170043 0.894743794982474 0.09324150660204633 -0.7913736451434266 0.5533538685326163 +20 ENSG0000010000 Tgd 526 G A chr20:526:G:A -304240 0.19899873487272135 0.9113453102334927 -0.22821177119288416 0.20668640408520686 +20 ENSG0000010000 Tgd 4770 A G chr20:4770:A:G -439756 0.3686522656569755 0.011047088889969192 -0.34645585924823075 0.9099026335734901 +20 ENSG0000010000 Tgd 6408 T A chr20:6408:T:A -364590 0.5364530192197352 0.4782511423762348 -0.8624740184993611 0.95514166886869 +20 ENSG0000010000 Tgd 3383 C G chr20:3383:C:G 357626 0.7096716140567708 0.4747800242810044 0.20741889737682606 0.9392151004672306 +20 ENSG0000010000 Tgd 9626 T G chr20:9626:T:G -211180 0.20170272892298768 0.9910851131580173 -0.10853683853194074 0.8247580418053095 +20 ENSG0000010000 Tgd 9910 T C chr20:9910:T:C 454521 0.5692290729227616 0.4909586270168763 -0.07460909223358714 0.04004570538962945 +20 ENSG0000010000 Tgd 1493 C G chr20:1493:C:G -136373 0.7003165397244652 0.7116479336645214 -0.4051025451557284 0.6134144841999275 +20 ENSG0000010000 Tgd 2870 G T chr20:2870:G:T -311699 0.8999646203051247 0.7332439529305443 -0.08434369586907353 0.9109222623588216 +20 ENSG0000010000 Tgd 3006 A G chr20:3006:A:G 232582 0.9456873613868986 0.23969525758580723 0.7410791837860975 0.2745025007476901 +20 ENSG0000010000 Tgd 8811 C A chr20:8811:C:A 231952 0.7265377545536263 0.9022347198222195 0.8174729420764382 0.4118668802112141 +20 ENSG0000010000 Tgd 9058 A C chr20:9058:A:C -419749 0.7553968660922687 0.5043948424349656 0.5590212840737869 0.4106859715021032 +20 ENSG0000010000 Tgd 2701 C T chr20:2701:C:T 30647 0.044635165200885285 0.026717879423465485 0.2777332468999283 0.6759464444144546 +20 ENSG0000010000 Tgd 7568 G C chr20:7568:G:C 282193 0.39934183549711955 0.19440358427669346 -0.9244506804535186 0.2513551273239257 +20 ENSG0000010000 Tgd 2237 C G chr20:2237:C:G 8306 0.46135699799833574 0.08254862985334199 0.31404520932277435 0.7138679577787846 +20 ENSG0000010000 Tgd 7172 T G chr20:7172:T:G 360279 0.2791418868419716 0.16136653103373266 0.6769917013953048 0.6073815688745275 +20 ENSG0000010000 Tgd 2904 C A chr20:2904:C:A 60625 0.7414464830670469 0.1684533735929824 0.3427843118248737 0.012199407381607269 +20 ENSG0000010000 Tgd 4477 T G chr20:4477:T:G -124519 0.17794022870564774 0.714412272233105 0.7853754114366192 0.5327665061350937 +20 ENSG0000010000 Tgd 7243 G C chr20:7243:G:C -34447 0.05241525618884968 0.0046657327463082154 0.5448193904369403 0.7673471242154859 +20 ENSG0000010000 Tgd 4092 C T chr20:4092:C:T -290300 0.0913864300849917 0.421682730525316 0.9785812499308579 0.33777952580679965 +20 ENSG0000010000 Tgd 3149 A T chr20:3149:A:T 425143 0.09660320577713966 0.8353850828889806 0.3282175089103412 0.7242874854570642 +20 ENSG0000010000 Tgd 722 G A chr20:722:G:A 355244 0.3271414661607114 0.5620541172235193 -0.6209049280781544 0.20791219605798303 +20 ENSG0000010000 Tgd 8876 A T chr20:8876:A:T -275836 0.10588531461787465 0.3233678279341873 -0.9700108557620721 0.6543387667978107 +20 ENSG0000010000 Tgd 197 G T chr20:197:G:T -18939 0.22009619374585354 0.6579617024591929 -0.4430847518154235 0.624285484817706 +20 ENSG0000010000 Tgd 720 A T chr20:720:A:T -68934 0.3015342486466849 0.5988690964846016 0.9662049858342749 0.10271177628501187 +20 ENSG0000010000 Tgd 8785 T C chr20:8785:T:C -400654 0.5998671451535394 0.9814158948575997 0.3926307318890905 0.6782226218628052 +20 ENSG0000010000 Tgd 2178 C T chr20:2178:C:T 166216 0.7617162829933094 0.6876250976172609 0.956043062382254 0.6667042185637969 +20 ENSG0000010000 Tgd 1107 C A chr20:1107:C:A 138093 0.9121032549816139 0.44891156541087773 0.022052282699822623 0.7420721082478243 +20 ENSG0000010000 Tgd 8249 A T chr20:8249:A:T -477757 0.616348674587466 0.8967794263665092 -0.3823027426541401 0.738175370634119 +20 ENSG0000010000 Tgd 3991 T C chr20:3991:T:C 22952 0.2966147303731127 0.1516705853920276 -0.591229339807646 0.03886880884189827 +20 ENSG0000010000 Tgd 9799 G C chr20:9799:G:C -359211 0.27812644330813474 0.6436020716054057 0.5209877645910899 0.5213519867359696 +20 ENSG0000010000 Tgd 6798 C A chr20:6798:C:A -259866 0.8469348455434526 0.3312702726030976 -0.5155020325509097 0.5397724403740458 +20 ENSG0000010000 Tgd 4069 T G chr20:4069:T:G 46802 0.32163699108023547 0.4423608901335486 -0.9879146804717649 0.8699968731563585 +20 ENSG0000010000 Tgd 1147 T A chr20:1147:T:A 165181 0.9920125688726604 0.9382745266275109 -0.7488780007994267 0.17450214882223314 +20 ENSG0000010000 Tgd 7653 C T chr20:7653:C:T 256729 0.19753626171443572 0.424016775015261 0.21170246972098083 0.3037976065655614 +20 ENSG0000010000 Tgd 9445 G T chr20:9445:G:T -214934 0.862425526837177 0.4811707070471045 0.9020263846599339 0.36022235345725884 +20 ENSG0000010000 Tgd 6189 T G chr20:6189:T:G -37184 0.42269725728998 0.6093942205230005 -0.1331390178155234 0.1567225895358935 +20 ENSG0000010000 Tgd 7898 A G chr20:7898:A:G -51842 0.8540422103049818 0.7588583224002795 0.8430649980937175 0.5955881782372332 +20 ENSG0000010000 Tgd 2504 T C chr20:2504:T:C -101070 0.4636512347001379 0.45360310586710084 -0.2497062301316546 0.6064193312999866 +20 ENSG0000010000 Tgd 1179 C T chr20:1179:C:T 249588 0.46925848123219416 0.15472445574501104 -0.6207483708235539 0.013821437975715556 +20 ENSG0000010000 Tgd 8204 C G chr20:8204:C:G -75794 0.9256910712705564 0.9402849852640158 0.9409852734535036 0.37377175280193525 +20 ENSG0000010000 Tgd 8021 C A chr20:8021:C:A -71356 0.8849995809706068 0.9924724692225698 -0.7510449828978478 0.9321974291059597 +20 ENSG0000010000 Tgd 2661 T G chr20:2661:T:G -232343 0.7712703787765353 0.7515774050522245 -0.302842624342317 0.7094193369532615 +20 ENSG0000010000 Tgd 6033 A G chr20:6033:A:G 471525 0.424040337917687 0.2467918116029565 -0.04454888351995412 0.9215470785372948 +20 ENSG0000010000 Tgd 5922 A T chr20:5922:A:T -225975 0.6054356355627682 0.9442652216633147 -0.705265220190763 0.2481673872288106 +20 ENSG0000010000 Tgd 9476 T A chr20:9476:T:A -377600 0.7709721855245962 0.6443973907203187 0.8337657061867076 0.39826925459030044 +20 ENSG0000010000 Tgd 9604 A T chr20:9604:A:T 418559 0.42294485990571673 0.8297495650266965 -0.4942575292015554 0.3029173463966412 +20 ENSG0000010000 Tgd 8736 G C chr20:8736:G:C 269584 0.41160899216281055 0.876400470169787 0.4553041587683253 0.08978456591192473 +20 ENSG0000010000 Tgd 9382 C T chr20:9382:C:T -217911 0.748730072450083 0.9300168659410644 -0.20405956061171016 0.3087922424555859 +20 ENSG0000010000 Tgd 2760 G A chr20:2760:G:A -398424 0.06984149496066294 0.6963167072671622 0.04992397750679123 0.6548666705865556 +20 ENSG0000010000 Tgd 7061 C T chr20:7061:C:T 238246 0.13433206228927164 0.48647125945973635 0.005227505393077481 0.11112801172740847 +20 ENSG0000010000 Tgd 9292 T A chr20:9292:T:A 286343 0.1827293992726402 0.7591646849504473 -0.4812961670317186 0.9023710156138534 +20 ENSG0000010000 Tgd 6698 G A chr20:6698:G:A 410543 0.6364336398700337 0.07980980197433818 -0.8285858723859707 0.12555689756933927 +20 ENSG0000010000 Tgd 1053 C A chr20:1053:C:A 114094 0.23478012888056865 0.48519435281160905 0.5210671886922291 0.010497069641913537 +20 ENSG0000010000 Tgd 4360 A T chr20:4360:A:T 47707 0.7917865366284694 0.3756658032758896 0.04014824311281484 0.9620958214000062 +20 ENSG0000010000 Tgd 4356 C G chr20:4356:C:G -147102 0.3707851222296058 0.8901521961620259 0.9988902705196112 0.8170303448539781 +20 ENSG0000010000 Tgd 5411 T A chr20:5411:T:A 131147 0.12289453945312856 0.5306293389161492 0.9021238788852783 0.7516883016246311 +20 ENSG0000010000 Tgd 7786 G T chr20:7786:G:T -496719 0.986181405470321 0.9575471426690944 0.6252380955544645 0.01761367380725975 +20 ENSG0000010000 Tgd 5902 A C chr20:5902:A:C 210860 0.44430615926950157 0.606763016317309 -0.1996696183203961 0.6129797530857206 +20 ENSG0000010000 Tgd 1334 C G chr20:1334:C:G 484701 0.9314834694674432 0.9308445042082809 0.9737429269900768 0.857242900228502 +20 ENSG0000010000 Tgd 1646 G C chr20:1646:G:C 136667 0.1950769551988093 0.1431614448864662 0.04010885769477479 0.572320732355692 +20 ENSG0000010000 Tgd 8159 A C chr20:8159:A:C 372786 0.6730621605836208 0.5487466602565318 0.7495715538681007 0.16888479853057983 +20 ENSG0000010000 Tgd 7312 A G chr20:7312:A:G 194830 0.5406679081983984 0.24335599848360434 -0.6591339744142815 0.9442656687131923 +20 ENSG0000010000 Tgd 1466 A G chr20:1466:A:G 250534 0.029221781792009405 0.9290034765673232 -0.3469984098874255 0.38410632582413035 +20 ENSG0000010000 Tgd 4594 T C chr20:4594:T:C 198281 0.4763023179136505 0.8975108837381099 -0.7538037796992605 0.13662067600200659 +20 ENSG0000010000 Tgd 8758 G A chr20:8758:G:A 334184 0.6917845482587897 0.8719406070098743 0.8635599102969778 0.7665710493096981 +20 ENSG0000010000 Tgd 9842 A C chr20:9842:A:C -104677 0.9101671257424557 0.7429678196907228 0.45005617114380736 0.6542657297883935 +20 ENSG0000010000 Tgd 9207 G T chr20:9207:G:T -265590 0.2590939485705641 0.290976502654555 -0.7772349552938429 0.3408976161244559 +20 ENSG0000010000 Tgd 9703 T A chr20:9703:T:A 100665 0.36773702597184077 0.8533303090436182 0.9081372377305492 0.5773399248509181 +20 ENSG0000010000 Tgd 28 C A chr20:28:C:A 118722 0.5356030403812055 0.8471185966442937 0.9596989963009728 0.3203233461343469 +20 ENSG0000010000 Tgd 5981 A G chr20:5981:A:G -490366 0.5382929433313163 0.4606027701193558 -0.710598426816643 0.9429470187688375 +20 ENSG0000010000 Tgd 3587 T C chr20:3587:T:C -347044 0.7470599313478968 0.8491274699664991 0.6555025831306995 0.035309521639953746 +20 ENSG0000010000 Tgd 5246 C A chr20:5246:C:A -213265 0.9968486044382249 0.7065222678629454 -0.04343450619165501 0.828858617070983 +20 ENSG0000010000 Tgd 8111 C G chr20:8111:C:G -438331 0.9811427951619787 0.333144546692835 0.6557693886275038 0.21140247260199388 +20 ENSG0000010000 Tgd 3688 A T chr20:3688:A:T 398397 0.48750465160157874 0.39180786385463007 0.9687790843101167 0.6595910605897306 +20 ENSG0000010000 Tgd 2609 A G chr20:2609:A:G -146200 0.4224374717317423 0.47342161827023543 -0.3033856785638007 0.39197135198617006 +20 ENSG0000010000 Tgd 1177 T G chr20:1177:T:G -397954 0.1309006834284855 0.7522664799636413 0.16076735952281096 0.8052667146628288 +20 ENSG0000010000 Tgd 4982 G T chr20:4982:G:T 105193 0.137560959472386 0.6959555259528883 -0.41783686135384324 0.14567805930641722 +20 ENSG0000010000 Tgd 3574 T A chr20:3574:T:A -120179 0.7259575117836988 0.5756820969428705 0.3566356120332963 0.9884957036716664 +20 ENSG0000010000 Tgd 2419 T A chr20:2419:T:A -399287 0.35558385382710955 0.4738757549198931 0.8901263930271881 0.11822949857485646 +20 ENSG0000010000 Tgd 8445 C G chr20:8445:C:G -344215 0.6269725465964556 0.4039939958229736 -0.932014344352446 0.24161456567978964 +20 ENSG0000010000 Tgd 8006 C T chr20:8006:C:T 184507 0.7452002344680699 0.7758498094364616 0.9823279201287807 0.6710651571963753 +20 ENSG0000010000 Tgd 1469 C G chr20:1469:C:G -114834 0.011602417528632114 0.11662763418731825 -0.7558968739328022 0.641767918274726 +20 ENSG0000010000 Tgd 8352 T A chr20:8352:T:A 115357 0.5729819088231722 0.5726305654607591 -0.4525503859858835 0.7456139355261525 +20 ENSG0000010000 Tgd 9714 T G chr20:9714:T:G 7711 0.9999541911825287 0.7027369844440853 -0.4032733057227269 0.12611120102809223 +20 ENSG0000010000 Tgd 5329 A T chr20:5329:A:T -74981 0.8128679372425519 0.019746388448748986 0.11212032761369395 0.5368803729764452 +20 ENSG0000010000 Tgd 8685 G A chr20:8685:G:A 44107 0.8371439396196718 0.5389817857276582 0.6376552103469921 0.6520489608493837 +20 ENSG0000010000 Tgd 3400 A T chr20:3400:A:T 403876 0.5991026065887204 0.17993755642566078 0.10944353710461963 0.8007124588637187 +20 ENSG0000010000 Tgd 2016 A T chr20:2016:A:T 103016 0.20622990021586785 0.16121026193962185 0.1249924191349816 0.8515986560457621 +20 ENSG0000010000 Tgd 574 T G chr20:574:T:G 491143 0.6581593677407918 0.24833708480447514 -0.9076674737600297 0.9458487990939887 +20 ENSG0000010000 Tgd 4808 G T chr20:4808:G:T 105103 0.4904428250722698 0.31293604912360196 0.8215663132968472 0.9968003647756949 +20 ENSG0000010000 Tgd 9932 T A chr20:9932:T:A 194804 0.8197632956857648 0.23710035560081855 -0.6238526978840333 0.300409520359554 +20 ENSG0000010000 Tgd 3527 T G chr20:3527:T:G -422029 0.5498486105722737 0.26067444221513203 0.29953788077324517 0.16415605524673546 +20 ENSG0000010000 Tgd 7473 A C chr20:7473:A:C 209388 0.4253433640316078 0.6945153708997662 0.07180863922481073 0.07148748797877595 +20 ENSG0000010000 Tgd 4414 T C chr20:4414:T:C 91021 0.6573180530054205 0.8205082082109707 0.20988938456837936 0.4202667861040401 +20 ENSG0000010000 Tgd 2515 C G chr20:2515:C:G -102651 0.025909863144291112 0.6036072466336018 -0.8449508060496267 0.12549660266890147 +20 ENSG0000010000 Tgd 1803 G A chr20:1803:G:A -154644 0.6401774889899354 0.3628194846901699 -0.3329653027941146 0.27397974936055614 +20 ENSG0000010000 Tgd 3699 C A chr20:3699:C:A -397296 0.37715598180506527 0.968773485885751 -0.24273529720629972 0.10589772673659675 +20 ENSG0000010000 Tgd 2024 T C chr20:2024:T:C 117429 0.8213432491332155 0.48961860012665803 0.057920237614217385 0.7007550802050971 +20 ENSG0000010000 Tgd 4621 C A chr20:4621:C:A 440122 0.047963285228218244 0.31799638976536915 0.5037458299035329 0.18149181174358509 +20 ENSG0000010000 Tgd 8712 T C chr20:8712:T:C -490042 0.686658348989229 0.7132226612828022 0.3151258696074539 0.1435274723501642 +20 ENSG0000010000 Tgd 9299 C A chr20:9299:C:A 463055 0.7254192727744093 0.9744998467724821 0.41500483121764886 0.24986251599741732 +20 ENSG0000010000 Tgd 9973 T G chr20:9973:T:G -128803 0.7984688987483517 0.5022292456538949 -0.4483540512231541 0.428337317638651 +20 ENSG0000010000 Tgd 3749 C A chr20:3749:C:A 493478 0.3056615025290458 0.7705784016306467 0.6904912157377687 0.6350420038804069 +20 ENSG0000010000 Tgd 1257 T A chr20:1257:T:A -326867 0.5753166977868343 0.08458512085236203 -0.42829827138543486 0.9296594179895347 +20 ENSG0000010000 Tgd 176 G T chr20:176:G:T 2955 0.4978052043543121 0.6851218640651883 0.3535483313810903 0.5328769359974866 +20 ENSG0000010000 Tgd 2043 G A chr20:2043:G:A 146223 0.19018400394086832 0.8313974197649752 -0.9854194862520684 0.42555393075115316 +20 ENSG0000010000 Tgd 8755 C T chr20:8755:C:T 274879 0.6611741107021897 0.9204589562368645 0.9983358365346773 0.9449964416815586 +20 ENSG0000010000 Tgd 9982 A G chr20:9982:A:G -323282 0.6745221684141856 0.8819305655636671 0.047032831665852814 0.22584350935846106 +20 ENSG0000010000 Tgd 1231 C T chr20:1231:C:T 38637 0.3532915335333615 0.05090656446458597 -0.008984276963848403 0.17131348051809073 +20 ENSG0000010000 Tgd 1856 C T chr20:1856:C:T 372128 0.539119622489639 0.7664139111176592 -0.7642691986253152 0.2998788149702664 +20 ENSG0000010000 Tgd 4810 C T chr20:4810:C:T -497658 0.7380257221398983 0.5688419445873907 -0.5650736104986613 0.30551497963204893 +20 ENSG0000010000 Tgd 8447 A G chr20:8447:A:G 435847 0.6177486915018542 0.4882664610258991 -0.2885118722037807 0.6159147181875521 +20 ENSG0000010000 Tgd 5383 C T chr20:5383:C:T -78402 0.3545323238437156 0.10133777879777406 -0.015907761491173122 0.0856590355900486 +20 ENSG0000010000 Tgd 8427 T G chr20:8427:T:G -370142 0.91310911243716 0.006910451916086635 0.5388952144478774 0.2508846181323315 +20 ENSG0000010000 Tgd 7712 G C chr20:7712:G:C -186177 0.3644956978286912 0.8921933858259173 0.07285476940190572 0.27021219297190224 +20 ENSG0000010000 Tgd 7186 G T chr20:7186:G:T -353332 0.3537377770773402 0.433960154695885 -0.28152650768196197 0.8706435562410221 +20 ENSG0000010000 Tgd 3252 A T chr20:3252:A:T -201261 0.04025630752504117 0.3945460052866918 0.4878479738714323 0.9010968124909321 +20 ENSG0000010000 Tgd 2627 T G chr20:2627:T:G 197557 0.9829287027254672 0.11879230604391777 -0.02186433151180056 0.49607202836141184 +20 ENSG0000010000 Tgd 2088 C G chr20:2088:C:G 26236 0.7259945565727446 0.741893200897149 0.6512786356933191 0.13228625250326875 +20 ENSG0000010000 Tgd 1768 A T chr20:1768:A:T -336903 0.3441205509007046 0.013648955280966657 0.3688753282503028 0.052987797093629795 +20 ENSG0000010000 Tgd 5606 G A chr20:5606:G:A -44574 0.4801930136193828 0.28222336982137886 -0.8347702061995881 0.42952298389002336 +20 ENSG0000010000 Tgd 2499 C A chr20:2499:C:A 406144 0.26353073115838355 0.7009557653021392 0.33266089589311787 0.42972976856093137 +20 ENSG0000010000 Tgd 7765 A T chr20:7765:A:T -302167 0.9925516683971279 0.5911961989768438 0.26895438356289403 0.23015480803952157 +20 ENSG0000010000 Tgd 2168 G A chr20:2168:G:A -212836 0.990398795844446 0.9290983315274799 -0.14739404592422645 0.6168508908111143 +20 ENSG0000010000 Tgd 6674 C T chr20:6674:C:T -267452 0.3361778514539886 0.47919523761682004 0.0197273854475144 0.6442292823463964 +20 ENSG0000010000 Tgd 4986 A C chr20:4986:A:C -118763 0.28055594073980106 0.35102451377798316 -0.16385160018550415 0.32052104403235854 +20 ENSG0000010000 Tgd 780 T A chr20:780:T:A -499439 0.05213063702308196 0.7447547042492002 -0.5760448979539132 0.4725861060163318 +20 ENSG0000010000 Tgd 9938 A G chr20:9938:A:G -306182 0.2522630464161052 0.4912863475351128 -0.3314357056564585 0.11241708478175348 +20 ENSG0000010000 Tgd 224 T C chr20:224:T:C -121917 0.7412921027096752 0.36138496356406813 0.5576166151301722 0.5293332015582106 +20 ENSG0000010000 Tgd 6089 T C chr20:6089:T:C -279765 0.5843272163275581 0.08723117327089458 -0.7872689644920021 0.6299290697414044 +20 ENSG0000010000 Tgd 9861 G A chr20:9861:G:A -421484 0.9418180029584394 0.6190103690542129 -0.3970471661485635 0.4747243215863031 +20 ENSG0000010000 Tgd 3310 T A chr20:3310:T:A -365959 0.19170672758081964 0.5504956819981569 -0.4949489848079287 0.8771982671886369 +20 ENSG0000010000 Tgd 9181 G A chr20:9181:G:A 455094 0.43612576326510677 0.4828206182942104 0.047525524069850444 0.9524917850745137 +20 ENSG0000010000 Tgd 359 T C chr20:359:T:C 230549 0.9674869412849414 0.2896563563156517 0.9116058433975989 0.06173259743747097 +20 ENSG0000010000 Tgd 3117 A T chr20:3117:A:T -40992 0.7507277914082882 0.38415041984989184 0.558744346950157 0.4014481104806896 +20 ENSG0000010000 Tgd 4449 A T chr20:4449:A:T 99678 0.2178077220329102 0.6967217475836077 0.7583100338075652 0.7908562303579068 +20 ENSG0000010000 Tgd 7462 T C chr20:7462:T:C 242658 0.26851465219371706 0.11910339572361928 -0.5521410994885496 0.5340322254447532 +20 ENSG0000010000 Tgd 4782 A T chr20:4782:A:T 487806 0.8836024722289778 0.9272479573858633 -0.4591302890571529 0.7908306969886157 +20 ENSG0000010000 Tgd 4080 T A chr20:4080:T:A -498533 0.6486455004473172 0.6326828793075645 0.9444372559951268 0.32523731033625375 +20 ENSG0000010000 Tgd 9000 C T chr20:9000:C:T -71822 0.8983357594272645 0.294895338450634 0.9705225684831056 0.6263293493174481 +20 ENSG0000010000 Tgd 171 C T chr20:171:C:T 265960 0.9652274644351736 0.17673523914804457 0.9432094099467767 0.5378513060186823 +20 ENSG0000010000 Tgd 9557 A G chr20:9557:A:G 491592 0.6538247187237826 0.8700257884430113 0.2686110824993504 0.5513269258063498 +20 ENSG0000010000 Tgd 7245 T C chr20:7245:T:C -218150 0.20391863272833666 0.6298006609658372 0.716442670716311 0.3960679447910624 +20 ENSG0000010000 Tgd 7309 T G chr20:7309:T:G -113453 0.1483341895205389 0.4790068871802915 -0.008077648557520911 0.4599307225334867 +20 ENSG0000010000 Tgd 2886 T G chr20:2886:T:G 489179 0.729479992243697 0.6475642717036921 -0.9579053921973673 0.1637557301101669 +20 ENSG0000010000 Tgd 2912 G T chr20:2912:G:T -427173 0.14352235996759444 0.426395030656858 -0.08995168046457991 0.6454736391038826 +20 ENSG0000010000 Tgd 6595 A T chr20:6595:A:T 262067 0.7504442021846229 0.011788529182177099 -0.8005401137787831 0.38460655815672273 +20 ENSG0000010000 Tgd 1803 A C chr20:1803:A:C -350436 0.9385983916177181 0.5996371806673474 0.584800868725192 0.010386776571423319 +20 ENSG0000010000 Tgd 1743 C A chr20:1743:C:A -287851 0.13923009842951162 0.7596717518780471 0.7847805834461181 0.8156494575886525 +20 ENSG0000010000 Tgd 5037 C G chr20:5037:C:G -337982 0.24380885851290446 0.543526438564369 -0.4650867189841592 0.5440692928578886 +20 ENSG0000010000 Tgd 348 C A chr20:348:C:A 36391 0.8864568683243049 0.41528467194613083 -0.9975791586612619 0.22508843246830157 +20 ENSG0000010000 Tgd 3714 T C chr20:3714:T:C 187199 0.2868462072751252 0.9216909176035978 0.3688349483123987 0.6870795220236456 +20 ENSG0000010000 Tgd 1842 G T chr20:1842:G:T -384515 0.2245224572847504 0.9564664882112225 -0.4363714552326814 0.07721365154594974 +20 ENSG0000010000 Tgd 5468 A C chr20:5468:A:C 468170 0.9247022265186429 0.0848043106167502 -0.9133063315673713 0.15195186591811258 +20 ENSG0000010000 Tgd 7023 C T chr20:7023:C:T 212437 0.42524454854592697 0.8931175520067913 0.3743214354152047 0.6251335137318446 +20 ENSG0000010000 Tgd 4703 C A chr20:4703:C:A -215739 0.916234355414292 0.6617317152702249 0.865763668200388 0.8109086954375927 +20 ENSG0000010000 Tgd 1252 A T chr20:1252:A:T 315565 0.6558541219427368 0.32025600334838167 -0.21880085100687463 0.7216221201721867 +20 ENSG0000010000 Tgd 7839 G C chr20:7839:G:C -348305 0.09044701846728775 0.9947716826761942 -0.6362553273508638 0.3856323802490245 +20 ENSG0000010000 Tgd 5232 C T chr20:5232:C:T 341105 0.9440302674021885 0.9216049033843585 -0.23362957807392437 0.549789921623507 +20 ENSG0000010000 Tgd 8827 G T chr20:8827:G:T -96690 0.08361772135618273 0.7149210529166516 0.05389189091140678 0.7768159652710366 +20 ENSG0000010000 Tgd 3594 A T chr20:3594:A:T -120721 0.0028661057597373363 0.9939053121998541 -0.9656906967997785 0.5588160935748548 +20 ENSG0000010000 Tgd 2189 T C chr20:2189:T:C -17248 0.14414024230280764 0.8533122059069602 0.9436392028829717 0.9130409549896112 +20 ENSG0000010000 Tgd 3974 A T chr20:3974:A:T -377070 0.9620519853814 0.7039628561070306 -0.2450784335571301 0.02732053552140597 +20 ENSG0000010000 Tgd 6959 C A chr20:6959:C:A 235473 0.10600983100196204 0.5816070740950874 -0.0463468605661812 0.5943317208260782 +20 ENSG0000010000 Tgd 2592 A T chr20:2592:A:T -117014 0.14127749263490208 0.24504580406148202 -0.9750445996346602 0.8312369248561379 +20 ENSG0000010000 Tgd 6824 G T chr20:6824:G:T 284447 0.5274500377369219 0.9487657643817938 -0.059630998797379764 0.7228348631411765 +20 ENSG0000010000 Tgd 7275 A C chr20:7275:A:C -383329 0.15588733598590487 0.8811571422402135 -0.9357617854450109 0.7513817961991327 +20 ENSG0000010000 Tgd 8246 T A chr20:8246:T:A -84355 0.8326800944180843 0.6799035440999415 0.751953027461417 0.5546017653546881 +20 ENSG0000010000 Tgd 4228 C T chr20:4228:C:T -55750 0.9314502340316819 0.27182760814668483 -0.8161269497647727 0.37818271981886287 +20 ENSG0000010000 Tgd 2051 T G chr20:2051:T:G 149114 0.05599682196159961 0.392290958640678 0.6450099311172326 0.9760114064569398 +20 ENSG0000010000 Tgd 9914 A G chr20:9914:A:G 607 0.3131896604053672 0.6418908343099048 0.6545073595713087 0.16565953516674767 +20 ENSG0000010000 Tgd 6087 G T chr20:6087:G:T -216969 0.1084008820682768 0.07780857654438633 0.20638033418055257 0.8467626652876749 +20 ENSG0000010000 Tgd 460 T C chr20:460:T:C -329334 0.5415679149811308 0.06531916716627728 0.1942215116467625 0.7567649189291695 +20 ENSG0000010000 Tgd 5065 A T chr20:5065:A:T -217757 0.08503935468690949 0.5701227751731635 -0.9102509235778553 0.986507479387786 +20 ENSG0000010000 Tgd 7927 C A chr20:7927:C:A 489341 0.30860485887884137 0.9805416267860616 0.5033588600516643 0.9587802838738132 +20 ENSG0000010000 Tgd 8196 T C chr20:8196:T:C 288363 0.39064130727714386 0.3558372927743997 -0.7409662201604723 0.6750117312914315 +20 ENSG0000010000 Tgd 5429 G A chr20:5429:G:A 26570 0.807494333200605 0.1501866580820479 0.174351018608649 0.38272962001320776 +20 ENSG0000010000 Tgd 9607 A C chr20:9607:A:C -330946 0.15153781087975182 0.4631062230374876 0.7704077456288445 0.09419757420469427 +20 ENSG0000010000 Tgd 3795 T C chr20:3795:T:C -30783 0.7853518585204897 0.33902070888013824 -0.2793672885973639 0.8560966004520728 +20 ENSG0000010000 Tgd 7060 A G chr20:7060:A:G -249275 0.20882064101852094 0.6103872329509038 -0.8500034219322257 0.15324900540958306 +20 ENSG0000010000 Tgd 8152 T C chr20:8152:T:C 73713 0.8675336760949128 0.7973830311108046 0.7902696890706968 0.49941334837689905 +20 ENSG0000010000 Tgd 7452 C T chr20:7452:C:T 479428 0.2956081789841688 0.06816183984367041 0.15302324836445247 0.35401510822132237 +20 ENSG0000010000 Tgd 1166 T G chr20:1166:T:G -229527 0.9861433094237815 0.9784837607743315 0.5262927394607344 0.442603342612399 +20 ENSG0000010000 Tgd 2302 A G chr20:2302:A:G -458485 0.3634721104726437 0.28662506789668807 -0.1819335392564394 0.6200638199837727 +20 ENSG0000010000 Tgd 2114 G C chr20:2114:G:C 37373 0.8448356436538093 0.9520449587229297 -0.25263380879922903 0.6825186959414261 +20 ENSG0000010000 Tgd 8290 G C chr20:8290:G:C 420029 0.8755364566389333 0.6825555864175824 0.2412274476503078 0.644222918510449 +20 ENSG0000010000 Tgd 4012 A T chr20:4012:A:T 394498 0.10529800721005045 0.37582168845985675 0.14026745258689544 0.8539753614880569 +20 ENSG0000010000 Tgd 3655 A C chr20:3655:A:C -11492 0.468488698024187 0.5351157553503402 0.6365794906743316 0.11000993179333743 +20 ENSG0000010000 Tgd 2954 A G chr20:2954:A:G 305533 0.43311439603172985 0.40152047074378006 -0.8710569394039385 0.34308111976416245 +20 ENSG0000010000 Tgd 9902 G T chr20:9902:G:T 236405 0.7412847614006658 0.11432643442135348 -0.09084270837482311 0.5455361405058605 +20 ENSG0000010000 Tgd 7700 C A chr20:7700:C:A 130275 0.7742055235824348 0.06240025860413656 0.6170671636088603 0.7897695699757309 +20 ENSG0000010000 Tgd 7757 T A chr20:7757:T:A -278234 0.8680206017415428 0.9526450094477563 0.3673428807097725 0.2705782620595336 +20 ENSG0000010000 Tgd 2886 A T chr20:2886:A:T -427377 0.27390531752309555 0.0817091114695131 0.7475517796308799 0.4519695111171739 +20 ENSG0000010000 Tgd 6877 T C chr20:6877:T:C -306980 0.8305490915011039 0.09244126003203224 0.8032834742744905 0.3426771287501037 +20 ENSG0000010000 Tgd 4865 C G chr20:4865:C:G 5020 0.4754994178973606 0.6888304932702883 -0.6786216800572005 0.6969933957185388 +20 ENSG0000010000 Tgd 5812 G A chr20:5812:G:A 88155 0.7830723739696985 0.5971286386144159 -0.8443825733255792 0.6682945258834277 +20 ENSG0000010000 Tgd 7515 T G chr20:7515:T:G 406285 0.3164078378201043 0.792016818895758 0.3478906215188895 0.26353989145287127 +20 ENSG0000010000 Tgd 7362 G T chr20:7362:G:T 130134 0.37755657148463484 0.3480855540168514 0.9047537623518556 0.9717727606590734 +20 ENSG0000010000 Tgd 9451 A C chr20:9451:A:C 353309 0.363794453562731 0.30194447112571376 -0.3860691561984242 0.8192324665329633 +20 ENSG0000010000 Tgd 2044 G C chr20:2044:G:C -381113 0.9263488588915303 0.45882356486010256 -0.25375702713586157 0.5532008185557791 +20 ENSG0000010000 Tgd 2665 C G chr20:2665:C:G 164909 0.28324836270580156 0.6203764895938451 0.8502711937708074 0.8571402698839146 +20 ENSG0000010000 Tgd 1436 A G chr20:1436:A:G -391289 0.4964049290861463 0.7517267586575872 0.854457818638291 0.10060237032094317 +20 ENSG0000010000 Tgd 7277 A C chr20:7277:A:C 393077 0.420640857606166 0.2228793708747644 -0.0907402403416051 0.3816987512512997 +20 ENSG0000010000 Tgd 3205 G A chr20:3205:G:A -132355 0.9676161020528615 0.9140293185706967 -0.17413051563510962 0.8205975572482835 +20 ENSG0000010000 Tgd 6485 A C chr20:6485:A:C 320192 0.22393659880430106 0.28360442271537434 0.7592143216532743 0.26523457147992613 +20 ENSG0000010000 Tgd 6795 T A chr20:6795:T:A 443914 0.9090590507876624 0.03267461073048461 -0.9475063658747771 0.7907196181195327 +20 ENSG0000010000 Tgd 8503 T G chr20:8503:T:G -246422 0.5557395813874179 0.3913623928476899 0.23253583378246945 0.39392442511559533 +20 ENSG0000010000 Tgd 846 G T chr20:846:G:T 485023 0.6362734913111604 0.9773556346305661 -0.6525654583704619 0.9042672009677202 +20 ENSG0000010000 Tgd 8476 T G chr20:8476:T:G -257811 0.09957792393881715 0.8011719742888977 0.008514093136380962 0.6318096274089575 +20 ENSG0000010000 Tgd 6423 C T chr20:6423:C:T 494784 0.3224046320003463 0.09325442532647699 -0.9487195396807635 0.012526584686824875 +20 ENSG0000010000 Tgd 9721 T A chr20:9721:T:A 148124 0.7075759138440525 0.9205943940013638 -0.8424549911648955 0.3830224442725224 +20 ENSG0000010000 Tgd 2139 G C chr20:2139:G:C -304383 0.23972188422473306 0.8979092405867221 -0.4061549873079522 0.5358818030775809 +20 ENSG0000010000 Tgd 4019 G C chr20:4019:G:C 191281 0.05174886640135068 0.082963369302272 -0.7124609406674205 0.02411768181434405 +20 ENSG0000010000 Tgd 9493 G A chr20:9493:G:A -387722 0.14183538617538682 0.26199467401657095 -0.6387446061853002 0.07830404685997064 +20 ENSG0000010000 Tgd 5922 T G chr20:5922:T:G -394439 0.49103695746840126 0.021956968409904243 -0.8528480606300044 0.9592579558793982 +20 ENSG0000010000 Tgd 1251 T G chr20:1251:T:G -106518 0.8897135206579039 0.6335517980776906 -0.09824294137136569 0.1619425411718087 +20 ENSG0000010000 Tgd 4895 A T chr20:4895:A:T 191710 0.5672938498199984 0.6066548589975307 -0.9370990527092349 0.9759399582405957 +20 ENSG0000010000 Tgd 5682 G A chr20:5682:G:A -333918 0.5217485557622971 0.25450102185147383 -0.7568127782218865 0.6065046634266203 +20 ENSG0000010000 Tgd 8782 A T chr20:8782:A:T -273187 0.8668742579586106 0.11478845699557938 -0.5660844291821479 0.3282121883960549 +20 ENSG0000010000 Tgd 3601 A T chr20:3601:A:T -219411 0.2736664822814976 0.19923753256521637 -0.8160603143490348 0.7083754905383707 +20 ENSG0000010000 Tgd 4823 T C chr20:4823:T:C -318639 0.19787644361747392 0.8460357776829219 0.4347922694844417 0.9619094277950606 +20 ENSG0000010000 Tgd 1686 C T chr20:1686:C:T 332673 0.2058318030369436 0.7220603487479075 -0.1330566572717231 0.44671157653863414 +20 ENSG0000010000 Tgd 9771 A G chr20:9771:A:G -49833 0.1997207743461581 0.3529155058708823 0.7957893555268416 0.8195223481372147 +20 ENSG0000010000 Tgd 7364 T A chr20:7364:T:A 36196 0.25306366076222986 0.40980826536918835 0.20776419083306807 0.8773748397115831 +20 ENSG0000010000 Tgd 8692 C G chr20:8692:C:G -468606 0.1146499527983682 0.8090404668650117 -0.14122639908050938 0.1867289767517654 +20 ENSG0000010000 Tgd 4020 A T chr20:4020:A:T 188866 0.3716602949199399 0.14503967597718948 -0.3710942101135313 0.010623366588879725 +20 ENSG0000010000 Tgd 179 C T chr20:179:C:T -12018 0.5674692526105003 0.32156123890537003 -0.5347025161737118 0.0671689076960481 +20 ENSG0000010000 Tgd 4647 A C chr20:4647:A:C 251058 0.6079043741991449 0.88336012368967 0.7198252777955676 0.07574937171022918 +20 ENSG0000010000 Tgd 6910 G C chr20:6910:G:C 352905 0.3201214089851857 0.1971232522253672 0.605450384228442 0.4991523174550015 +20 ENSG0000010000 Tgd 4497 G A chr20:4497:G:A -369880 0.4527851057882586 0.6014306793129053 0.1823421922751891 0.23718549528596847 +20 ENSG0000010000 Tgd 349 C A chr20:349:C:A 174933 0.7833056364663173 0.5757587402161566 -0.9907059682660828 0.4623100760883201 +20 ENSG0000010000 Tgd 2148 G A chr20:2148:G:A 439345 0.5334670090528911 0.5275136831337232 -0.32522026233709367 0.017256019766514374 +20 ENSG0000010000 Tgd 7699 A G chr20:7699:A:G 258386 0.3009982725581045 0.31718966181346975 -0.3083510637232014 0.08068744175801976 +20 ENSG0000010000 Tgd 5132 G A chr20:5132:G:A -87567 0.2984438143406579 0.9839668382300566 -0.013326751460547737 0.6414560384615166 +20 ENSG0000010000 Tgd 1990 C A chr20:1990:C:A -469290 0.22401435708876127 0.8254565299331845 -0.722531153185134 0.9935468310083164 +20 ENSG0000010000 Tgd 7139 A T chr20:7139:A:T 259282 0.9022764847597627 0.36887953293433495 0.8057611664765829 0.9895754647473723 +20 ENSG0000010000 Tgd 861 C A chr20:861:C:A -383815 0.04800339003760257 0.30429009404064844 -0.47254573808120237 0.6882336740727564 +20 ENSG0000010000 Tgd 6219 C T chr20:6219:C:T 469784 0.13776332574675376 0.4606937625996874 -0.7474225860933561 0.8620330043200662 +20 ENSG0000010000 Tgd 9571 A T chr20:9571:A:T 105956 0.4779268179928434 0.4901038406517315 -0.4389167976094581 0.7728713299344011 +20 ENSG0000010000 Tgd 7909 T A chr20:7909:T:A -223374 0.766201982619123 0.7113813764065077 -0.2939806050283429 0.8357065546438057 +20 ENSG0000010000 Tgd 3972 T A chr20:3972:T:A -421206 0.9717652089491915 0.06026692846771675 -0.9737437863573588 0.21691933262856475 +20 ENSG0000010000 Tgd 6309 T G chr20:6309:T:G -390388 0.3404501394082714 0.8139954178819291 0.5232050646490549 0.5144133897841004 +20 ENSG0000010000 Tgd 5135 C G chr20:5135:C:G 187120 0.15399892514800262 0.5045114092950558 0.8282505293199496 0.219566046012793 +20 ENSG0000010000 Tgd 5958 T G chr20:5958:T:G -302917 0.06863931028424519 0.42309398326423997 0.37253199975411255 0.9515431013327952 +20 ENSG0000010000 Tgd 9458 A T chr20:9458:A:T -16655 0.8761962362168236 0.7450259932145414 -0.5188750771196495 0.8942039562716034 +20 ENSG0000010000 Tgd 3065 C A chr20:3065:C:A -626 0.6618855039096281 0.4526409160491587 -0.4688425493489774 0.9270007919203785 +20 ENSG0000010000 Tgd 1378 C G chr20:1378:C:G -277633 0.15062004623508451 0.5021903919491799 0.015853648390464548 0.054103915005171706 +20 ENSG0000010000 Tgd 4467 C A chr20:4467:C:A -448479 0.6486217482575962 0.7320016095639762 -0.15482325562936627 0.29471188868776094 +20 ENSG0000010000 Tgd 6598 T C chr20:6598:T:C 55286 0.607448134523751 0.5186184602496425 -0.7816308784311932 0.050821578068275086 +20 ENSG0000010000 Tgd 4079 A T chr20:4079:A:T -379217 0.053137771003383794 0.03568795751952003 -0.4676435107176433 0.06678153852820087 +20 ENSG0000010000 Tgd 1656 C T chr20:1656:C:T 425473 0.6202207408809086 0.7158233180981829 -0.216183820472875 0.10220296769342122 +20 ENSG0000010000 Tgd 4396 G T chr20:4396:G:T -320663 0.7857276514438948 0.3476331132419348 -0.42401490053753044 0.5967170833549696 +20 ENSG0000010000 Tgd 51 A T chr20:51:A:T 27685 0.9077824406360926 0.6221183499452346 0.4781815008122352 0.8527113753539405 +20 ENSG0000010000 Tgd 3910 T C chr20:3910:T:C 214544 0.06945463394109497 0.1873444120001443 0.7997384437205839 0.1426918215996085 +20 ENSG0000010000 Tgd 209 C A chr20:209:C:A -313862 0.974370854078473 0.8812575271500428 -0.6585497754931013 0.7605004914867622 +20 ENSG0000010000 Tgd 160 C G chr20:160:C:G 111486 0.0010064727686891484 0.8732185382210494 -0.054863510886043354 0.04613134307494396 +20 ENSG0000010000 Tgd 285 C T chr20:285:C:T 50784 0.5031464708395654 0.7549924786879342 0.5505131050036862 0.10089247130824375 +20 ENSG0000010000 Tgd 5500 G C chr20:5500:G:C -118015 0.4587507621464211 0.827749478464025 -0.3977319343364665 0.33440513123930277 +20 ENSG0000010000 Tgd 8485 G A chr20:8485:G:A -216951 0.685784157509423 0.7282155427321815 -0.9585454441919867 0.9786588001616942 +20 ENSG0000010000 Tgd 3609 T C chr20:3609:T:C 22014 0.030904674860595116 0.5775842051283451 0.3916121717287686 0.43128979026571296 +20 ENSG0000010000 Tgd 3381 A T chr20:3381:A:T 465368 0.9548144070638586 0.6387337528760109 0.9309061210442167 0.8772668918614448 +20 ENSG0000010000 Tgd 8928 G T chr20:8928:G:T -221804 0.9103273352911052 0.34884505635496155 -0.3376086594011454 0.5895586912399305 +20 ENSG0000010000 Tgd 4527 C T chr20:4527:C:T -456904 0.5795168319350311 0.7018356348818126 0.6683431358988199 0.12383830234427862 +20 ENSG0000010000 Tgd 7456 G T chr20:7456:G:T -11031 0.6809230681525748 0.523186169316407 -0.4204364475042355 0.55858270820719 +20 ENSG0000010000 Tgd 4723 A C chr20:4723:A:C -483651 0.45385818213934515 0.21732530208689937 0.6509412019412459 0.12431233013525664 +20 ENSG0000010000 Tgd 8002 C A chr20:8002:C:A -48774 0.3522555206734933 0.83411005139829 -0.9001959077800294 0.13858106565377118 +20 ENSG0000010000 Tgd 4642 T A chr20:4642:T:A 247841 0.2706688951152879 0.9959142560739304 -0.6065451736442629 0.5856396116192756 +20 ENSG0000010000 Tgd 1323 C T chr20:1323:C:T -466303 0.4731777677903679 0.3546322379166521 0.6234181773439089 0.6374076040748848 +20 ENSG0000010000 Tgd 6924 G A chr20:6924:G:A 436413 0.2612609112277189 0.3020226552861839 -0.3785283986732071 0.5643437040253017 +20 ENSG0000010000 Tgd 5284 C T chr20:5284:C:T -63465 0.5542837694251773 0.3010622658207721 -0.8288041457931081 0.5670984249874318 +20 ENSG0000010000 Tgd 7556 T G chr20:7556:T:G 320411 0.8759214791197504 0.4368928156498245 -0.72278024961693 0.44245943001984994 +20 ENSG0000010000 Tgd 5133 C G chr20:5133:C:G -128601 0.42766917099470314 0.42050566495542907 -0.17948275117152956 0.028645265412671338 +20 ENSG0000010000 Tgd 9158 A G chr20:9158:A:G -407276 0.7558564554198502 0.6152085505936203 -0.39522002955329305 0.24340300977037915 +20 ENSG0000010000 Tgd 8392 C T chr20:8392:C:T 151050 0.5432695515447289 0.5655746003821882 -0.41331362644529324 0.755579838173555 +20 ENSG0000010000 Tgd 6434 T G chr20:6434:T:G 202629 0.005952845981775257 0.8074810263737702 0.7498217451275628 0.46076053219555946 +20 ENSG0000010000 Tgd 891 C A chr20:891:C:A -150318 0.5943396843776036 0.821940133650429 0.13088680031102728 0.6909023094846031 +20 ENSG0000010000 Tgd 998 G T chr20:998:G:T -265598 0.8950523411905822 0.6396681282837368 -0.6904490098224252 0.6286112231431896 +20 ENSG0000010000 Tgd 106 G T chr20:106:G:T -379720 0.06714206188943761 0.15302208515845728 0.7597981262361171 0.5203027384114769 +20 ENSG0000010000 Tgd 4051 T A chr20:4051:T:A -3246 0.024656383937049275 0.5058045047805896 -0.21857221341649957 0.9261183982244848 +20 ENSG0000010000 Tgd 4914 C G chr20:4914:C:G 401055 0.6581593201842794 0.12319653058315583 -0.707507258114261 0.022636220169239076 +20 ENSG0000010000 Tgd 2322 T G chr20:2322:T:G 3805 0.29003618873245285 0.6675355292858159 0.9181828288549749 0.49347117222079684 +20 ENSG0000010000 Tgd 4509 A G chr20:4509:A:G -62853 0.8134936051430773 0.1481665300426681 -0.4331555596428771 0.12100637098137189 +20 ENSG0000010000 Tgd 6381 A C chr20:6381:A:C -464261 0.6451089877666706 0.893220973440941 0.2397529251050856 0.043589165011049924 +20 ENSG0000010000 Tgd 5812 T G chr20:5812:T:G 425288 0.7230652679380042 0.276904039152861 0.9635073715197224 0.3583899151544104 +20 ENSG0000010000 Tgd 8245 T C chr20:8245:T:C 446392 0.7062246168036435 0.3906243258196499 -0.8744684580788482 0.6562633282560952 +20 ENSG0000010000 Tgd 5765 C G chr20:5765:C:G 249923 0.8586639000974362 0.1400392970319102 0.5699218774230417 0.6587855009781342 +20 ENSG0000010000 Tgd 6455 A G chr20:6455:A:G -105188 0.9625550096612595 0.6058417980296299 -0.6392509255403438 0.7087916833943488 +20 ENSG0000010000 Tgd 8307 C T chr20:8307:C:T 231663 0.32407661221066186 0.9551945968026274 -0.3038095595763144 0.6178575490642814 +20 ENSG0000010000 Tgd 6616 A T chr20:6616:A:T -257041 0.09654044110522397 0.1062204353469155 0.8684678178924661 0.4769365935052612 +20 ENSG0000010000 Tgd 3794 T A chr20:3794:T:A 443502 0.8807554108947363 0.7281631595825616 -0.23183307415524324 0.9733464076044864 +20 ENSG0000010000 Tgd 1055 A C chr20:1055:A:C -379966 0.03741827493013328 0.7499349420732385 -0.1169430946804293 0.37494779132997064 +20 ENSG0000010000 Tgd 483 T C chr20:483:T:C -387110 0.6987257260792674 0.37762894580674644 0.9777417277901734 0.5742058819674831 +20 ENSG0000010000 Tgd 3273 T C chr20:3273:T:C 14958 0.43751485406494894 0.2860893325917164 -0.5976145156897024 0.162927492459334 +20 ENSG0000010000 Tgd 8660 T A chr20:8660:T:A 110384 0.024243054010835707 0.9598323380102086 -0.8075877695748268 0.03420595265328012 +20 ENSG0000010000 Tgd 2303 A C chr20:2303:A:C 312002 0.4080273700378464 0.5465808426178332 -0.8560697683585985 0.18611905187874167 +20 ENSG0000010000 Tgd 8654 G T chr20:8654:G:T 372837 0.2074747798619424 0.827575739277399 0.0017005704657144793 0.35712870742276587 +20 ENSG0000010000 Tgd 9154 T A chr20:9154:T:A -39803 0.42751174886130316 0.37611822690052465 -0.8582647656030593 0.07906566240687062 +20 ENSG0000010000 Tgd 8475 C A chr20:8475:C:A -376345 0.49871224336753417 0.05147900880492906 0.08107604579507988 0.023519935844817683 +20 ENSG0000010000 Tgd 4750 C G chr20:4750:C:G 237435 0.35790519466961035 0.8724425350984434 -0.6842739586813031 0.2887809264414186 +20 ENSG0000010000 Tgd 8756 T C chr20:8756:T:C -81388 0.6186449159432068 0.5459416188114725 0.783616753084577 0.58318973926088 +20 ENSG0000010000 Tgd 4310 C G chr20:4310:C:G -226447 0.20051125686273896 0.8880280313248627 -0.881216062019935 0.2050290744344909 +20 ENSG0000010000 Tgd 5401 A T chr20:5401:A:T 17530 0.07291190181420792 0.9479975965906395 0.8086477310955777 0.7033877395776543 +20 ENSG0000010000 Tgd 580 C A chr20:580:C:A 496050 0.4162401750545771 0.7392893926235485 0.8587271732180339 0.8876311149066226 +20 ENSG0000010000 Tgd 7845 T C chr20:7845:T:C 258466 0.04174097704933 0.035600084786092556 0.015208530802205633 0.6506866315596359 +20 ENSG0000010000 Tgd 3732 A T chr20:3732:A:T 60134 0.6081388954840188 0.3793883896018655 0.36719013360028807 0.01907676926958159 +20 ENSG0000010000 Tgd 7900 A G chr20:7900:A:G 302875 0.3772278107363025 0.12523739360063257 0.40267557541778043 0.549995379109924 +20 ENSG0000010000 Tgd 1894 G A chr20:1894:G:A 440726 0.6156532018075477 0.9035512906887283 -0.2964218080990668 0.3437825115106128 +20 ENSG0000010000 Tgd 950 T G chr20:950:T:G 283785 0.7525690636659811 0.8077350317923787 0.07243514907432513 0.04673394016137559 +20 ENSG0000010000 Tgd 245 T A chr20:245:T:A -419667 0.05665458833214554 0.4385558827265611 -0.43480804497421643 0.3148117573210433 +20 ENSG0000010000 Tgd 9870 T C chr20:9870:T:C -363983 0.6061238452629644 0.4787013654230745 -0.7552472851188439 0.07772702998147525 +20 ENSG0000010000 Tgd 4100 T G chr20:4100:T:G 239513 0.7352186278508963 0.3569583140137804 0.8302017280274652 0.2210670017607382 +20 ENSG0000010000 Tgd 4960 T C chr20:4960:T:C -165653 0.6977716873691914 0.5034454025654358 -0.8920049317682468 0.9005249521912859 +20 ENSG0000010000 Tgd 7967 C A chr20:7967:C:A -286558 0.912049212583389 0.8414253516192615 0.04198989615642912 0.30563426184033415 +20 ENSG0000010000 Tgd 9060 T A chr20:9060:T:A -109521 0.7249107570676483 0.7879400561896058 -0.9282646480514154 0.23587013881388005 +20 ENSG0000010000 Tgd 7214 G A chr20:7214:G:A -477677 0.49890749034527837 0.03375618361159094 -0.4440653385484197 0.38479248218322115 +20 ENSG0000010000 Tgd 1385 A C chr20:1385:A:C 396086 0.6097477256054897 0.4953574986670052 0.7255456206588176 0.38527858663034226 +20 ENSG0000010000 Tgd 728 G T chr20:728:G:T 191982 0.4310849646664555 0.05225965127648746 -0.38970385445198286 0.5420076175945499 +20 ENSG0000010000 Tgd 5699 A C chr20:5699:A:C 467519 0.8281575657982347 0.2625327394175804 0.5066367326819692 0.21732760534804288 +20 ENSG0000010000 Tgd 449 C G chr20:449:C:G 407796 0.4275491891996016 0.7292261341852432 0.4708289765179263 0.058061474618235964 +20 ENSG0000010000 Tgd 1790 G C chr20:1790:G:C 400217 0.9908911581186657 0.5347613801323066 -0.15232995789345294 0.7195009752790238 +20 ENSG0000010000 Tgd 8502 C T chr20:8502:C:T -100188 0.4673324729921956 0.992613076602378 -0.5235461871046916 0.9078048811939972 +20 ENSG0000010000 Tgd 4599 C A chr20:4599:C:A -237927 0.771339204481278 0.29582491768548147 0.1421652644068181 0.03956760247000823 +20 ENSG0000010000 Tgd 4494 C A chr20:4494:C:A -369656 0.30689515596956807 0.6607764759733482 0.6719995925503601 0.8477450754091561 +20 ENSG0000010000 Tgd 7272 G A chr20:7272:G:A -38722 0.008870701986845586 0.0370037627658657 -0.28255269705939434 0.6381053562647179 +20 ENSG0000010000 Tgd 9120 T G chr20:9120:T:G -438570 0.5795703227731157 0.07954689321253938 0.79408856645716 0.551896422816161 +20 ENSG0000010000 Tgd 1050 G T chr20:1050:G:T -229461 0.7659768297280051 0.27614434256807563 0.7381107433874745 0.1280952576040588 +20 ENSG0000010000 Tgd 2859 T A chr20:2859:T:A -256026 0.1144465629354181 0.03850177812766642 0.36888276795624453 0.8607097072964054 +20 ENSG0000010000 Tgd 9501 C A chr20:9501:C:A 80290 0.7173576968010695 0.06081286781805595 0.4290991275306215 0.25979569526990537 +20 ENSG0000010000 Tgd 4218 A C chr20:4218:A:C 66693 0.7183192971701403 0.6005788388453189 -0.30054069892818513 0.07840166360460965 +20 ENSG0000010000 Tgd 6988 C T chr20:6988:C:T -474106 0.32654054170077096 0.7881644618532578 -0.33002842999847504 0.4087294141240032 +20 ENSG0000010000 Tgd 6140 G C chr20:6140:G:C 152126 0.03115740537876499 0.36830191347457897 -0.4182547341241165 0.15091319002926934 +20 ENSG0000010000 Tgd 9687 T C chr20:9687:T:C 35608 0.7157679705386888 0.742043417008089 0.5669342962128892 0.7131273990475288 +20 ENSG0000010000 Tgd 3521 G A chr20:3521:G:A 188976 0.7262597616767487 0.38108966322699056 0.9956417031468761 0.07936652732807524 +20 ENSG0000010000 Tgd 1267 T G chr20:1267:T:G 65148 0.7330456608626422 0.8475950798279017 0.05551279780574947 0.052380072440914104 +20 ENSG0000010000 Tgd 7739 G C chr20:7739:G:C -217742 0.19502359506494504 0.575243736006806 0.8221390432719735 0.32935581865780245 +20 ENSG0000010000 Tgd 5931 T G chr20:5931:T:G -169892 0.7481882793634895 0.1154169193884218 -0.5179070466010649 0.7330655318398098 +20 ENSG0000010000 Tgd 6717 C A chr20:6717:C:A -130918 0.5604571290734667 0.07644376840170852 -0.27540600816413874 0.48467036495814736 +20 ENSG0000010000 Tgd 3775 T G chr20:3775:T:G 206850 0.5847553362392086 0.13814015392620604 -0.47944209283804984 0.287598304385172 +20 ENSG0000010000 Tgd 5143 T G chr20:5143:T:G 163360 0.881441241298951 0.1981042169024979 -0.6401685792743312 0.4546150759942586 +20 ENSG0000010000 Tgd 2733 A G chr20:2733:A:G -223831 0.7655095573855845 0.7113818744579342 -0.06027946259298944 0.1018943748270835 +20 ENSG0000010000 Tgd 559 G A chr20:559:G:A 223566 0.1669356375182679 0.07301470735950577 0.029794184370040666 0.5297803722597985 +20 ENSG0000010000 Tgd 2089 G T chr20:2089:G:T 246568 0.29339189171068103 0.3368082932936125 0.6494311675184055 0.33730384110574807 +20 ENSG0000010000 Tgd 9974 A C chr20:9974:A:C 496062 0.44889534198250036 0.4088747250350713 -0.1004925706878681 0.8349698675964359 +20 ENSG0000010000 Tgd 4740 G T chr20:4740:G:T 269070 0.18345077875038573 0.765955713313506 0.832683694662244 0.9366848247860715 +20 ENSG0000010000 Tgd 1373 T A chr20:1373:T:A 122385 0.5930482772728346 0.6739070910916086 -0.09294568927027913 0.3211164389338229 +20 ENSG0000010000 Tgd 2896 C A chr20:2896:C:A -256455 0.2973485327757408 0.34111721104598003 0.1282626765620356 0.8974043240224454 +20 ENSG0000010000 Tgd 9500 G C chr20:9500:G:C -161520 0.38406774639024055 0.757300214308618 0.9070273361086332 0.04289249478409572 +20 ENSG0000010000 Tgd 3452 G C chr20:3452:G:C 103075 0.8795837433299235 0.3143673919101546 -0.30530876986993927 0.16642694467628394 +20 ENSG0000010000 Tgd 4717 C G chr20:4717:C:G -39763 0.2236333629887488 0.16932077175735538 0.8784097569837133 0.2601695861206707 +20 ENSG0000010000 Tgd 4566 T A chr20:4566:T:A -283110 0.5521634432583301 0.5086981710408981 -0.6622951622702165 0.5987931480827835 +20 ENSG0000010000 Tgd 652 T A chr20:652:T:A 12088 0.8325044946551189 0.025777305435691455 -0.5937181222165002 0.9418641524011782 +20 ENSG0000010000 Tgd 9358 T G chr20:9358:T:G -190732 0.9179951929272329 0.7162509091669484 0.8383673406354206 0.12082064910948756 +20 ENSG0000010000 Tgd 7083 G C chr20:7083:G:C -408917 0.8645027513564976 0.9930772504095225 0.46326748533123085 0.11734617758893315 +20 ENSG0000010000 Tgd 5796 A T chr20:5796:A:T 262693 0.07435032969054367 0.15672719111338385 -0.32932567185002526 0.45401059421146894 +20 ENSG0000010000 Tgd 8403 A C chr20:8403:A:C 435615 0.9247299808141354 0.4333776243063717 0.8647360012695742 0.7944032019285523 +20 ENSG0000010000 Tgd 5203 T A chr20:5203:T:A 495290 0.6344971554524083 0.007970588251305588 -0.7262506546624994 0.37683284785779336 +20 ENSG0000010000 Tgd 3608 T C chr20:3608:T:C -7049 0.15143310639640062 0.813868851863629 0.4671213700879573 0.283317073983402 +20 ENSG0000010000 Tgd 3254 A T chr20:3254:A:T -496647 0.4343187814001833 0.49069115190012125 0.22243437481741557 0.710280519671268 +20 ENSG0000010000 Tgd 636 G C chr20:636:G:C 143173 0.38029022984971383 0.5838989558422251 0.27542925400590557 0.4847488298783501 +20 ENSG0000010000 Tgd 2951 C T chr20:2951:C:T 417544 0.29211591681820004 0.48505995042787464 0.5934923534099383 0.39281784581574986 +20 ENSG0000010000 Tgd 5852 G C chr20:5852:G:C -398778 0.21893052840506588 0.9629189512200295 0.7936367952072783 0.7641726820020681 +20 ENSG0000010000 Tgd 6875 G C chr20:6875:G:C -240587 0.6624181898300743 0.11581917983438395 -0.07052813535458569 0.31958704856002507 +20 ENSG0000010000 Tgd 1861 C G chr20:1861:C:G 239056 0.1280578656023873 0.8821714481989944 0.6802416563737586 0.8641452182954936 +20 ENSG0000010000 Tgd 9848 G T chr20:9848:G:T -469631 0.290930235891967 0.5074874029688996 0.7796212263552598 0.7830450665622712 +20 ENSG0000010000 Tgd 997 C G chr20:997:C:G -89611 0.8090305435802903 0.4251992806693875 -0.47860123347686634 0.05557873271442134 +20 ENSG0000010000 Tgd 7955 T C chr20:7955:T:C 167173 0.8185245845141152 0.3085106495591725 -0.18037691382601806 0.5729331909846243 +20 ENSG0000010000 Tgd 2729 T A chr20:2729:T:A 493921 0.9682557405032512 0.6107514003640724 -0.74156933121441 0.540227542861551 +20 ENSG0000010000 Tgd 346 G A chr20:346:G:A 318343 0.7047305206454402 0.9122285645656334 0.5336841011943361 0.5533412962362267 +20 ENSG0000010000 Tgd 807 T C chr20:807:T:C 61483 0.19843981404019362 0.15699291108659685 0.07139762335309796 0.8598631128676435 +20 ENSG0000010000 Tgd 3758 C T chr20:3758:C:T 454889 0.37387994923816703 0.4133952797622613 0.10590234001479071 0.24945504379327432 +20 ENSG0000010000 Tgd 224 A G chr20:224:A:G 329783 0.48489994587216645 0.15694550635732496 -0.3970671292507 0.23077523394617394 +20 ENSG0000010000 Tgd 4052 A C chr20:4052:A:C 286343 0.12364283064749715 0.7840536115903909 0.3105519175641378 0.13206199626980414 +20 ENSG0000010000 Tgd 4424 A G chr20:4424:A:G -478867 0.014741783906906614 0.8302515189476158 0.2097437220659042 0.15269570938841331 +20 ENSG0000010000 Tgd 9637 G T chr20:9637:G:T 371861 0.6056915809162189 0.31218970406630453 -0.35254653654765034 0.5128432755376389 +20 ENSG0000010000 Tgd 384 G T chr20:384:G:T -395479 0.2642699552272437 0.6560507087126461 -0.0571992937239898 0.2919474152259904 +20 ENSG0000010000 Tgd 1525 T G chr20:1525:T:G 88247 0.27855790021530924 0.28442298552144873 0.4057589252770528 0.5070869113755928 +20 ENSG0000010000 Tgd 6266 A G chr20:6266:A:G 262899 0.39364518189025954 0.3727376666866271 0.09316283039120932 0.10919599103792067 +20 ENSG0000010000 Tgd 3672 A G chr20:3672:A:G 308667 0.23211554770980236 0.3698216265202039 0.12630653543693482 0.6431757464356661 +20 ENSG0000010000 Tgd 5447 T A chr20:5447:T:A -399978 0.5608854231927969 0.20768181878945013 0.8841865582736053 0.5938161231481961 +20 ENSG0000010000 Tgd 1375 T G chr20:1375:T:G 146435 0.8380703961366016 0.5234056690561205 0.6793000186478972 0.760821017818133 +20 ENSG0000010000 Tgd 966 G C chr20:966:G:C -68135 0.31145495728039085 0.33786848064007924 -0.6987760508580549 0.32212153874567595 +20 ENSG0000010000 Tgd 9263 G A chr20:9263:G:A -218830 0.6903973386378897 0.7550379303277246 0.5893915815461708 0.5460431467541728 +20 ENSG0000010000 Tgd 5129 T C chr20:5129:T:C -16217 0.7088681718930329 0.5144311156482043 0.7173058202815799 0.9927626035536546 +20 ENSG0000010000 Tgd 1335 A G chr20:1335:A:G 233222 0.0775044439411614 0.12728248355453242 -0.9727509593651726 0.520419079381232 +20 ENSG0000010000 Tgd 1991 G A chr20:1991:G:A -459041 0.885502833308147 0.49518452711941363 0.2523298234217408 0.5250645060740872 +20 ENSG0000010000 Tgd 2292 A C chr20:2292:A:C -376705 0.43547940251040684 0.29422365665393313 0.8439404350552884 0.6770064765426257 +20 ENSG0000010000 Tgd 8561 C T chr20:8561:C:T 341811 0.6139998208880079 0.7144748000148929 0.038759568400945854 0.25198812353341227 +20 ENSG0000010000 Tgd 7584 T C chr20:7584:T:C 472113 0.7467642405638862 0.9961865384310198 0.8556832989355809 0.16507397273819202 +20 ENSG0000010000 Tgd 7764 A C chr20:7764:A:C -63475 0.17922578119001586 0.4704934363592267 0.9866206344511528 0.006596826721196353 +20 ENSG0000010000 Tgd 3075 T A chr20:3075:T:A 63852 0.458593579612934 0.09471456752052743 0.2499455283387615 0.5948600065506738 +20 ENSG0000010000 Tgd 1094 C T chr20:1094:C:T -138286 0.6288217530707231 0.9278794988441517 -0.45083877020794794 0.8209336760982812 +20 ENSG0000010000 Tgd 6983 G C chr20:6983:G:C 88368 0.5410169932365368 0.6593675703003117 -0.8450477481985224 0.15326938124651687 +20 ENSG0000010000 Tgd 3547 C T chr20:3547:C:T -224290 0.5636597655886569 0.12670408783021925 0.044635602642849825 0.6451852981693169 +20 ENSG0000010000 Tgd 6275 G T chr20:6275:G:T -323736 0.0026707856607802727 0.23183103642677683 -0.567113085220184 0.9296175675805692 +20 ENSG0000010000 Tgd 2401 G A chr20:2401:G:A -160956 0.07778742831910646 0.9698420692398338 -0.7260501457496695 0.8074271530080536 +20 ENSG0000010000 Tgd 6970 G C chr20:6970:G:C -182745 0.5003751051426487 0.1172964963374502 0.12029027034709827 0.37793224208910536 +20 ENSG0000010000 Tgd 6317 G C chr20:6317:G:C -173095 0.8386494258194096 0.31697192438457533 -0.8436006772028566 0.6057756148900765 +20 ENSG0000010000 Tgd 3505 T C chr20:3505:T:C 245902 0.1428839999428101 0.43724324226741385 -0.11670636400441081 0.6954046547947532 +20 ENSG0000010000 Tgd 4105 A G chr20:4105:A:G 183768 0.3481804890782565 0.025295554594236824 -0.26862564898472563 0.4666098047269436 +20 ENSG0000010000 Tgd 5669 G T chr20:5669:G:T 146944 0.5597940227113278 0.9979001128718717 0.8788142977801563 0.38307495815181475 +20 ENSG0000010000 Tgd 2933 A T chr20:2933:A:T -36445 0.3609913775772049 0.19488860670935015 0.1723768161295458 0.3291230932028172 +20 ENSG0000010000 Tgd 6044 C A chr20:6044:C:A 136249 0.27302783007568254 0.6472181176763133 0.28334812043212154 0.39889570814276826 +20 ENSG0000010000 Tgd 4146 C A chr20:4146:C:A 99975 0.8233257087351865 0.8631853216739707 0.8551496784509611 0.9972343458156191 +20 ENSG0000010000 Tgd 7447 G T chr20:7447:G:T -3554 0.7499359985808791 0.6475484948648985 0.09117467414484448 0.10478339531388424 +20 ENSG0000010000 Tgd 6055 A T chr20:6055:A:T 239916 0.7361961690851127 0.8709132213215761 -0.7367035883244184 0.4201530105116245 +20 ENSG0000010000 Tgd 1957 A G chr20:1957:A:G 168444 0.7105908696526696 0.31423655224945735 0.715780609012894 0.27820068763509403 +20 ENSG0000010000 Tgd 3182 A C chr20:3182:A:C 377944 0.6719909224527331 0.899666483078005 0.7954729454116367 0.17004433405264474 +20 ENSG0000010000 Tgd 9615 C A chr20:9615:C:A 486233 0.6644953370330712 0.41637872783628604 0.33544492229284595 0.06242192260838998 +20 ENSG0000010000 Tgd 3162 T C chr20:3162:T:C -411953 0.17258522989898073 0.04450842943434008 0.21705805061285788 0.6890279892233041 +20 ENSG0000010000 Tgd 6706 T A chr20:6706:T:A -173721 0.27376313925206197 0.3506847777792407 -0.317095019426163 0.568605092460435 +20 ENSG0000010000 Tgd 1411 G A chr20:1411:G:A -378091 0.9180110923242697 0.18250097132884247 -0.8271646919003295 0.31818378729788493 +20 ENSG0000010000 Tgd 330 T A chr20:330:T:A -271908 0.6379456175456163 0.46034909845348393 0.7543967772167437 0.9432940915486617 +20 ENSG0000010000 Tgd 5043 C A chr20:5043:C:A -102265 0.7059139630725723 0.17800403594198366 -0.7191478525841244 0.31622543892688143 +20 ENSG0000010000 Tgd 3703 T C chr20:3703:T:C 426488 0.19922464472883994 0.9792782090226735 -0.48129182014527694 0.4401587255618021 +20 ENSG0000010000 Tgd 1515 G C chr20:1515:G:C 106806 0.36361319831653827 0.7723705443875931 0.04608546867479579 0.8296705763294948 +20 ENSG0000010000 Tgd 2794 A G chr20:2794:A:G -336733 0.5379487839990206 0.2106627970468672 0.40437493374725264 0.34757460917802124 +20 ENSG0000010000 Tgd 4730 T C chr20:4730:T:C 233640 0.9684904553276691 0.5516112061579352 0.4862635701044653 0.2696811627273763 +20 ENSG0000010000 Tgd 8410 T C chr20:8410:T:C -271144 0.4676881973508441 0.031448050751681444 -0.7694036287511914 0.6586738490274738 +20 ENSG0000010000 Tgd 3055 G T chr20:3055:G:T -10057 0.5868207612856549 0.37228274765438896 -0.2441796860351444 0.5888023909581722 +20 ENSG0000010000 Tgd 555 C A chr20:555:C:A 160049 0.35888414732611995 0.9010240585200362 -0.6824990001111066 0.4760204261569512 +20 ENSG0000010000 Tgd 5517 A T chr20:5517:A:T 457505 0.35800453503635243 0.16274564316005424 0.09355621317268481 0.7522931319082394 +20 ENSG0000010000 Tgd 7193 T C chr20:7193:T:C 258510 0.3732147783111178 0.33787826063154325 0.3571116835050747 0.3008731245256128 +20 ENSG0000010000 Tgd 3839 A G chr20:3839:A:G -53418 0.7740724479359461 0.9539819402805566 -0.19849974523371383 0.029526615752741223 +20 ENSG0000010000 Tgd 9779 T C chr20:9779:T:C 326874 0.9599132988885052 0.970325127917518 -0.3814529211392488 0.7660572888800463 +20 ENSG0000010000 Tgd 5671 T G chr20:5671:T:G -499116 0.6586086015961394 0.20040653558786758 -0.6558631315636287 0.3082192261986054 +20 ENSG0000010000 Tgd 3025 G A chr20:3025:G:A 259309 0.24473252262277845 0.6847135764013843 0.6913367923439817 0.37488355264022816 +20 ENSG0000010000 Tgd 7821 T C chr20:7821:T:C -395234 0.4708006944494625 0.6867864384803719 0.3975594969465117 0.9129202129157903 +20 ENSG0000010000 Tgd 6166 G T chr20:6166:G:T 300122 0.9169497348057095 0.3875739136971711 -0.36328660304778393 0.9353271355285699 +20 ENSG0000010000 Tgd 6552 A C chr20:6552:A:C 12029 0.6698766778441452 0.9702256663622629 -0.9462074604378039 0.8857025407993332 +20 ENSG0000010000 Tgd 2919 T C chr20:2919:T:C -120122 0.33985095099699436 0.8232381418465937 0.2211330473299351 0.7519327755703223 +20 ENSG0000010000 Tgd 1266 G T chr20:1266:G:T -453603 0.21123234407557478 0.43540062824525194 -0.32082668864627895 0.6543908900223357 +20 ENSG0000010000 Tgd 6975 T C chr20:6975:T:C -173797 0.3868155157213876 0.821275014286131 -0.9303466787782388 0.9585542327170227 +20 ENSG0000010000 Tgd 6910 G A chr20:6910:G:A -12494 0.8062289363342559 0.34628686820019494 0.46534131618447727 0.6562127351507843 +20 ENSG0000010000 Tgd 6627 A T chr20:6627:A:T -165478 0.12873951028795694 0.5069704307913055 0.3725972988410602 0.012577070375183467 +20 ENSG0000010000 Tgd 6582 G A chr20:6582:G:A -182330 0.4249812011320072 0.7420650097289471 -0.7680831610614651 0.807317964990556 +20 ENSG0000010000 Tgd 7378 C G chr20:7378:C:G 246610 0.3350635084820419 0.5350241658968496 -0.2702764256049375 0.7857092290346377 +20 ENSG0000010000 Tgd 6948 G A chr20:6948:G:A -342308 0.006956728824344838 0.9482012162668785 0.4151294319354446 0.2585787153945523 +20 ENSG0000010000 Tgd 8437 A G chr20:8437:A:G -204602 0.03984444678985655 0.8678967169644043 -0.07949856866741012 0.05102343756166665 +20 ENSG0000010000 Tgd 9820 G C chr20:9820:G:C 207784 0.2961444539340864 0.8191693426931674 0.085496995854907 0.17954945214797888 +20 ENSG0000010000 Tgd 5848 G A chr20:5848:G:A -31528 0.3246325500136863 0.6359826999576023 0.19155781137471317 0.3578872376469702 +20 ENSG0000010000 Tgd 600 G T chr20:600:G:T -316255 0.08404685955483615 0.09457257483940285 0.4535748086071656 0.6332871029820802 +20 ENSG0000010000 Tgd 7064 G T chr20:7064:G:T 463405 0.8255714096395707 0.8349179024418169 0.46537555486687476 0.5240351887904048 +20 ENSG0000010000 Tgd 7511 A T chr20:7511:A:T 138953 0.9768433326766655 0.6378144831394886 0.764073775725405 0.38253108222871746 +20 ENSG0000010000 Tgd 1291 A T chr20:1291:A:T 496523 0.7467670310799628 0.7215939585335212 0.4853698295790756 0.08020399766427619 +20 ENSG0000010000 Tgd 7102 A T chr20:7102:A:T 98626 0.26097574826269154 0.3032014192311575 0.028079145240152092 0.8543894058460723 +20 ENSG0000010000 Tgd 3994 A C chr20:3994:A:C 101186 0.4729184002817367 0.7607190455159415 -0.12610873170514791 0.7471229229135395 +20 ENSG0000010000 Tgd 3043 C A chr20:3043:C:A 133992 0.3986706354450167 0.181260412024023 -0.430174987425217 0.006045998593983055 +20 ENSG0000010000 Tgd 3394 A G chr20:3394:A:G 189137 0.12976694311774262 0.2670532797458859 0.19815890178469142 0.9759217247457936 +20 ENSG0000010000 Tgd 5213 A T chr20:5213:A:T -264255 0.018072923339966684 0.32460883424474085 -0.8725550828667541 0.28854348057088103 +20 ENSG0000010000 Tgd 9984 C G chr20:9984:C:G -1295 0.9298726957861865 0.01256722467355964 -0.3188080442004979 0.34701994844381556 +20 ENSG0000010000 Tgd 7281 T G chr20:7281:T:G 395857 0.7425711564643281 0.21063739457905561 0.3954507286848634 0.673312965576881 +20 ENSG0000010000 Tgd 4190 G A chr20:4190:G:A 192792 0.8522916776784754 0.9677236086026468 0.26276812682358197 0.5617644104954768 +20 ENSG0000010000 Tgd 5658 A T chr20:5658:A:T 284346 0.9848686049103121 0.36919145512605256 -0.416353914873935 0.31602274788951634 +20 ENSG0000010000 Tgd 7658 A T chr20:7658:A:T 155216 0.5849368882681004 0.6242651369543848 0.12978487359778268 0.4159776018547267 +20 ENSG0000010000 Tgd 384 C G chr20:384:C:G -253880 0.37528433592003785 0.5375927100457056 -0.24314231265899933 0.948870273193855 +20 ENSG0000010000 Tgd 2024 A G chr20:2024:A:G -271091 0.21130517119266767 0.11063276656527077 -0.421302047690415 0.8650283953171848 +20 ENSG0000010000 Tgd 6572 G C chr20:6572:G:C 287775 0.21775260134175412 0.9004589065853397 -0.4422405612557607 0.7707291720495485 +20 ENSG0000010000 Tgd 1731 C G chr20:1731:C:G -263967 0.8590565875468102 0.49483321425935756 -0.07217211594755324 0.826312297795905 +20 ENSG0000010000 Tgd 7364 G C chr20:7364:G:C -496501 0.5326657059033684 0.3340548482755936 -0.07195702707483465 0.17309839750579312 +20 ENSG0000010000 Tgd 1611 T A chr20:1611:T:A 148938 0.224192612905592 0.6097060637170097 0.0067225098447483145 0.08142530932999097 +20 ENSG0000010000 Tgd 9349 G A chr20:9349:G:A -159192 0.6098125074054357 0.16645887173195284 0.25099024879803555 0.6846786973169108 +20 ENSG0000010000 Tgd 6067 A G chr20:6067:A:G 78874 0.511335453863727 0.19303157814077287 0.826413529535819 0.45831112858426015 +20 ENSG0000010000 Tgd 3921 T G chr20:3921:T:G 482663 0.7127925226195579 0.1997853020036533 -0.7346998856517388 0.06574801052027354 +20 ENSG0000010000 Tgd 507 T G chr20:507:T:G -18502 0.24504697087162053 0.6032489869270711 0.9794266557974165 0.7969568032972589 +20 ENSG0000010000 Tgd 2610 T G chr20:2610:T:G 257120 0.9624740263062884 0.00688331386900376 -0.9353548633750739 0.6771955032791224 +20 ENSG0000010000 Tgd 4261 A C chr20:4261:A:C 351089 0.39839673659434716 0.8223157579090485 0.5375230318293938 0.3640098943787068 +20 ENSG0000010000 Tgd 8382 T C chr20:8382:T:C 294758 0.8252285911128817 0.7535778566570471 -0.7764325332344442 0.16978451269938075 +20 ENSG0000010000 Tgd 6765 C T chr20:6765:C:T 457323 0.2430686711933694 0.4825910047448052 -0.47098459158650496 0.3306956594615692 +20 ENSG0000010000 Tgd 1214 T C chr20:1214:T:C -140923 0.29529206968243504 0.4446720654566676 0.5747478969451212 0.6998621106718766 +20 ENSG0000010000 Tgd 9310 C A chr20:9310:C:A 298304 0.14002098253387185 0.5217792934807421 -0.9481190261092554 0.8802904233446737 +20 ENSG0000010000 Tgd 9234 C T chr20:9234:C:T 95213 0.6338945798929136 0.4752848424991878 -0.12027529368879342 0.29558473684107395 +20 ENSG0000010000 Tgd 2107 T C chr20:2107:T:C 400881 0.3842266742684376 0.636762330144033 -0.9439905904096493 0.21245038146262712 +20 ENSG0000010000 Tgd 4964 T A chr20:4964:T:A -227978 0.36416179479017374 0.5085915606130453 0.7404651194232332 0.5173011422264485 +20 ENSG0000010000 Tgd 7815 T C chr20:7815:T:C 175127 0.15587685694646403 0.8526104725978917 -0.37140753085408496 0.374988220711058 +20 ENSG0000010000 Tgd 7951 T G chr20:7951:T:G -316094 0.4839984245384753 0.3798723668920442 0.3374896339617408 0.06568784359115828 +20 ENSG0000010000 Tgd 3684 C T chr20:3684:C:T -264794 0.15008852093156833 0.6086412353665706 0.45752364083043107 0.12047182835151744 +20 ENSG0000010000 Tgd 3227 C G chr20:3227:C:G -18367 0.5694079914145358 0.638636580901608 -0.975598427057607 0.7465103247083736 +20 ENSG0000010000 Tgd 8588 C A chr20:8588:C:A -82152 0.6264020286414028 0.9520282695406308 0.014833004283871132 0.2722020873183845 +20 ENSG0000010000 Tgd 8762 G T chr20:8762:G:T -243422 0.25607207266442367 0.7394357784292448 0.37939807677765836 0.6511564084862551 +20 ENSG0000010000 Tgd 4016 T G chr20:4016:T:G -313951 0.040232792343031454 0.6091377084386597 0.1039513092857085 0.09226783698325856 +20 ENSG0000010000 Tgd 3114 A T chr20:3114:A:T 47941 0.30276085481692183 0.20773204585601568 -0.5121188076484593 0.7619188151038375 +20 ENSG0000010000 Tgd 7820 G A chr20:7820:G:A 63015 0.8816407083080157 0.05108279972417895 0.5800322537706151 0.07398149154506177 +20 ENSG0000010000 Tgd 7837 A G chr20:7837:A:G -412564 0.4760358050271588 0.09987590866065643 0.1787517400830081 0.5986954762394981 +20 ENSG0000010000 Tgd 4915 A G chr20:4915:A:G 402969 0.9049888410532765 0.7199814534672907 -0.11471636925047846 0.6429847250849303 +20 ENSG0000010000 Tgd 9650 G A chr20:9650:G:A -236024 0.7545602500972812 0.601354146530801 -0.014789720905897141 0.17735534421586058 +20 ENSG0000010000 Tgd 8312 G C chr20:8312:G:C 497652 0.6452796407016907 0.2641999041085017 0.06438005341622222 0.34180114165703246 +20 ENSG0000010000 Tgd 9196 C G chr20:9196:C:G -383116 0.9772289973244981 0.9456970183713754 -0.02483911802593952 0.31988834075237677 +20 ENSG0000010000 Tgd 8349 A G chr20:8349:A:G 205666 0.3046409792793391 0.9252953370066723 -0.11360333349657492 0.6382450924163459 +20 ENSG0000010000 Tgd 3494 C G chr20:3494:C:G -392084 0.6847463198010728 0.9275514975899956 -0.5794161473064361 0.6722153477701771 +20 ENSG0000010000 Tgd 5305 G T chr20:5305:G:T 393761 0.15794316388758434 0.6625907432819356 -0.3486374772085701 0.5169498307717834 +20 ENSG0000010000 Tgd 7763 G C chr20:7763:G:C -260166 0.9328435455475406 0.4719816739434747 0.7124750738507364 0.3043145028086031 +20 ENSG0000010000 Tgd 2376 G C chr20:2376:G:C -54043 0.5632864042635426 0.7626952485525879 -0.9886549448635766 0.9400473175322788 +20 ENSG0000010000 Tgd 907 G C chr20:907:G:C 177162 0.8053707565362027 0.9749857593841084 0.5340971987576382 0.020460143951434865 +20 ENSG0000010000 Tgd 3314 T C chr20:3314:T:C -190884 0.8325517354419468 0.02367899806682605 -0.14500330700099529 0.3830239276912767 +20 ENSG0000010000 Tgd 9144 G C chr20:9144:G:C -387976 0.07442691358281528 0.16041794661792386 0.4456982982111377 0.9415526631663942 +20 ENSG0000010000 Tgd 9715 G A chr20:9715:G:A 319176 0.6594182356451675 0.6878009659031905 0.8177746937645771 0.48755430724171006 +20 ENSG0000010000 Tgd 4590 G A chr20:4590:G:A -393633 0.05611456662139791 0.34269193020497424 0.07579142405761519 0.43868624861301836 +20 ENSG0000010000 Tgd 4657 A G chr20:4657:A:G -359193 0.8808497395353482 0.07398876044560598 0.9543575163966849 0.7327165715274482 +20 ENSG0000010000 Tgd 2487 T C chr20:2487:T:C 101975 0.1999943074720828 0.08800515859023628 -0.5095466624521896 0.5731604347380889 +20 ENSG0000010000 Tgd 4272 C A chr20:4272:C:A -352710 0.7721007151149651 0.06800390683654933 0.5718014195449845 0.711691287266606 +20 ENSG0000010000 Tgd 5144 C G chr20:5144:C:G 283572 0.8845852182419063 0.18414002896299309 -0.06334720212694589 0.46134288658083666 +20 ENSG0000010000 Tgd 5457 T C chr20:5457:T:C -232238 0.6036168914113214 0.9326812477643661 -0.7194601279617783 0.6425979965431106 +20 ENSG0000010000 Tgd 7002 C A chr20:7002:C:A 93194 0.43720691647868204 0.032084017692418754 0.008423117892159215 0.7984799665416995 +20 ENSG0000010000 Tgd 8828 G C chr20:8828:G:C 102737 0.33375256981234136 0.06710947852159888 -0.8488948558970273 0.0930513770003118 +20 ENSG0000010000 Tgd 9148 A T chr20:9148:A:T 337383 0.5135003614894996 0.8514859459380079 0.14785048250104293 0.4689783489213991 +20 ENSG0000010000 Tgd 3128 A G chr20:3128:A:G 357479 0.2768649121054646 0.4512885875206871 0.7610811739318024 0.73919765271286 +20 ENSG0000010000 Tgd 5414 A T chr20:5414:A:T 179309 0.5752237687990793 0.45404708033587005 0.5622258289543711 0.7397191531463586 +20 ENSG0000010000 Tgd 7085 A G chr20:7085:A:G 102656 0.2938137874480631 0.6236897470669645 -0.22010500700963065 0.0095293672010653 +20 ENSG0000010000 Tgd 5282 G T chr20:5282:G:T -228574 0.8555746318615226 0.5843764817307763 0.5355576772484074 0.5328319107167092 +20 ENSG0000010000 Tgd 3283 C T chr20:3283:C:T -301980 0.7729920010885879 0.20614417127133655 -0.6368265583977626 0.027198266013626873 +20 ENSG0000010000 Tgd 9862 A T chr20:9862:A:T 66310 0.34851960059002485 0.06926688050822194 0.7411121027966774 0.928537036686195 +20 ENSG0000010000 Tgd 3422 T C chr20:3422:T:C -328780 0.42428363852950646 0.2710779401136848 0.8726045328360537 0.2180185735491886 +20 ENSG0000010000 Tgd 5822 A T chr20:5822:A:T 420269 0.8988796319394308 0.43964094015292887 0.6683144859673633 0.375738827976573 +20 ENSG0000010000 Tgd 7274 T G chr20:7274:T:G -448396 0.446812387097976 0.39917820095000955 -0.5887354646476548 0.38112438333501647 +20 ENSG0000010000 Tgd 2043 A T chr20:2043:A:T 31316 0.9132832108311618 0.7245183402038826 -0.7565924948024305 0.7568497505145396 +20 ENSG0000010000 Tgd 1972 G C chr20:1972:G:C 286099 0.9953575604921547 0.41512786739305507 -0.5793450774974809 0.0917001870944456 +20 ENSG0000010000 Tgd 8306 C G chr20:8306:C:G -232315 0.508735255241337 0.944896842963649 -0.9677090792766871 0.3806491038546581 +20 ENSG0000010000 Tgd 6882 G A chr20:6882:G:A -128090 0.36039244343140553 0.30998172489206965 -0.8693887973703611 0.9459946571138527 +20 ENSG0000010000 Tgd 4927 T A chr20:4927:T:A 182028 0.6435819552106367 0.3896862110193209 -0.05727708316072788 0.9513578350862132 +20 ENSG0000010000 Tgd 4501 C A chr20:4501:C:A -352428 0.8474148083403567 0.17735838565661943 -0.9814521055229262 0.5191033975377869 +20 ENSG0000010000 Tgd 2298 G A chr20:2298:G:A -435847 0.5962044879971464 0.2098255967076499 0.47969842941987784 0.2937914949158752 +20 ENSG0000010000 Tgd 6798 T G chr20:6798:T:G -319205 0.17463748109557908 0.5185996812976911 -0.6972390004699429 0.8096081714966099 +20 ENSG0000010000 Tgd 2976 C A chr20:2976:C:A 324764 0.16237371437236758 0.4975553915208346 -0.38787036532678765 0.6256871750936727 +20 ENSG0000010000 Tgd 4345 C A chr20:4345:C:A 321316 0.02583003291176289 0.02849689043179482 -0.058995350685376424 0.735215888680191 +20 ENSG0000010000 Tgd 2365 G A chr20:2365:G:A 65680 0.3770367708988658 0.5985074767658316 0.05040920033663854 0.1590144057871038 +20 ENSG0000010000 Tgd 245 C T chr20:245:C:T -403402 0.4198828785731755 0.0663257249624325 0.9374608021332229 0.4649688864230023 +20 ENSG0000010000 Tgd 6801 G T chr20:6801:G:T 398541 0.6032710955249154 0.6368552371913315 -0.3771382350289305 0.470017493901025 +20 ENSG0000010000 Tgd 4209 T C chr20:4209:T:C 188258 0.5399860915957594 0.9569053546608207 0.33686390096418983 0.0973018917911652 +20 ENSG0000010000 Tgd 8075 G C chr20:8075:G:C 430000 0.6150145538540795 0.24977879394757296 -0.498658594718177 0.7303002430700509 +20 ENSG0000010000 Tgd 4934 C G chr20:4934:C:G 200822 0.590784657894946 0.5169043583956889 0.9752858561811273 0.26745914777467933 +20 ENSG0000010000 Tgd 2158 C G chr20:2158:C:G -107025 0.66120182831005 0.5793685595423752 0.8692488201074067 0.035191087664574384 +20 ENSG0000010000 Tgd 6309 A T chr20:6309:A:T -308979 0.01432173060591857 0.6346306505360755 0.6707581847127111 0.23859149946066227 +20 ENSG0000010000 Tgd 6501 C A chr20:6501:C:A 99876 0.4807763731766108 0.8576804499618841 -0.6245034690393074 0.869656315164063 +20 ENSG0000010000 Tgd 9457 T G chr20:9457:T:G 151493 0.2628046389362173 0.4398629972176188 0.4899208587304531 0.6558050444479475 +20 ENSG0000010000 Tgd 8430 T C chr20:8430:T:C -142454 0.8069884991047613 0.48735514858370854 0.09780157292360059 0.6635848222330727 +20 ENSG0000010000 Tgd 5610 C A chr20:5610:C:A 319938 0.36542224456753214 0.6422926934466807 0.9295070997375068 0.12710194114214873 +20 ENSG0000010000 Tgd 3722 G A chr20:3722:G:A -373880 0.550464769547398 0.2957134330742005 0.7466134778801239 0.30772337509030295 +20 ENSG0000010000 Tgd 7147 A T chr20:7147:A:T -83131 0.8200266207847723 0.8856242746006309 0.021809238119095298 0.14256671656051867 +20 ENSG0000010000 Tgd 3635 A T chr20:3635:A:T 269038 0.7445957985068596 0.5255746886203907 0.5598753862346886 0.5633201204990318 +20 ENSG0000010000 Tgd 8693 A C chr20:8693:A:C 65661 0.23042354504536644 0.9471634998707089 0.061740147572062254 0.37509764797680856 +20 ENSG0000010000 Tgd 1641 T G chr20:1641:T:G 399987 0.20219612329022119 0.04891218214524351 0.9382927559152112 0.40147197084277814 +20 ENSG0000010000 Tgd 6387 G C chr20:6387:G:C -357268 0.7215476478497932 0.2999932095434785 -0.850259032080632 0.7086327177003147 +20 ENSG0000010000 Tgd 5106 T A chr20:5106:T:A -437901 0.7551695660529697 0.14030327009999422 -0.03813575472770259 0.16109270382544638 +20 ENSG0000010000 Tgd 3973 G T chr20:3973:G:T 177468 0.41900927864759907 0.5914164050919659 -0.5028533960233774 0.35105692537472477 +20 ENSG0000010000 Tgd 3708 C T chr20:3708:C:T 435999 0.4014405319353298 0.7259789611373467 0.17185945725949248 0.6726450024298903 +20 ENSG0000010000 Tgd 3373 G T chr20:3373:G:T 204892 0.2754702997251197 0.32746944584525395 0.27351321454781297 0.5210996610511051 +20 ENSG0000010000 Tgd 8590 A G chr20:8590:A:G -256541 0.6604214343299865 0.29882221536517417 -0.7502710142543991 0.743168819050682 +20 ENSG0000010000 Tgd 7445 T A chr20:7445:T:A 422984 0.9789929595161247 0.9105061644316227 -0.31724561936802465 0.272830684926647 +20 ENSG0000010000 Tgd 672 G C chr20:672:G:C -381682 0.6268983369061774 0.42591057408585076 -0.6630879808032168 0.710050910374116 +20 ENSG0000010000 Tgd 7984 C T chr20:7984:C:T 48236 0.10305016553828827 0.9976053068917937 0.20663213669858016 0.5994479348377882 +20 ENSG0000010000 Tgd 5941 T G chr20:5941:T:G 377353 0.7015990463140935 0.43247731344159035 -0.8866949582389012 0.10608490718381154 +20 ENSG0000010000 Tgd 4591 C G chr20:4591:C:G 199377 0.8362962473276933 0.9830866110076106 -0.8338132796745583 0.10202985160337769 +20 ENSG0000010000 Tgd 7956 T G chr20:7956:T:G -267858 0.5910844388139771 0.665628487361626 -0.7920690924331169 0.7811410053628278 +20 ENSG0000010000 Tgd 5910 A C chr20:5910:A:C 178521 0.7881363514084002 0.852233033334784 0.14668984507637117 0.523242625461809 +20 ENSG0000010000 Tgd 6533 G A chr20:6533:G:A -273467 0.5669299973602421 0.024144423235366252 0.8918995161199903 0.09970539618272001 +20 ENSG0000010000 Tgd 6753 A G chr20:6753:A:G 390691 0.8909446466975973 0.3585889325914414 0.3660233966119546 0.3530260716870872 +20 ENSG0000010000 Tgd 4075 C G chr20:4075:C:G 321779 0.04779911283040339 0.45820457264113734 0.9819513802946704 0.2639105239573309 +20 ENSG0000010000 Tgd 2632 T C chr20:2632:T:C 276685 0.4013208728530939 0.34853914216882154 0.6309389050611556 0.8448751259545726 +20 ENSG0000010000 Tgd 1457 T C chr20:1457:T:C 368937 0.3058351658381384 0.9141713136579146 -0.8191350305162113 0.40665919992038174 +20 ENSG0000010000 Tgd 8147 T G chr20:8147:T:G -288032 0.2646803919671177 0.7073960861969041 -0.29881219063697406 0.8060916024024137 +20 ENSG0000010000 Tgd 5923 C A chr20:5923:C:A -383105 0.18978975401704634 0.3105275847675675 0.012238557640139591 0.6426654324153424 +20 ENSG0000010000 Tgd 4854 T G chr20:4854:T:G 148513 0.6956360867316674 0.19861961225691194 -0.8189155651380784 0.598371412983407 +20 ENSG0000010000 Tgd 6630 C T chr20:6630:C:T 250663 0.3401639501216095 0.3537996515390034 -0.7339354318192852 0.3858549205401718 +20 ENSG0000010000 Tgd 4816 A C chr20:4816:A:C -264255 0.4425360547463151 0.04077284221279309 0.09597443275171225 0.6678538063517555 +20 ENSG0000010000 Tgd 4486 A G chr20:4486:A:G -264628 0.8332479647925428 0.9832622946722445 -0.5092965234050759 0.22660681920435682 +20 ENSG0000010000 Tgd 3539 T A chr20:3539:T:A -188790 0.24368020120703038 0.020773953628028474 0.224441028882165 0.8380927891247789 +20 ENSG0000010000 Tgd 6792 T G chr20:6792:T:G -304905 0.8479047754300488 0.5808956131310524 0.25451021753932324 0.8887155369031454 +20 ENSG0000010000 Tgd 6343 C G chr20:6343:C:G -111788 0.3645145289603833 0.9255058313676876 -0.5305883836723162 0.5408287418687128 +20 ENSG0000010000 Tgd 1263 T C chr20:1263:T:C 401717 0.8274478911329491 0.7024348173059176 0.5911141565185103 0.5793795091408186 +20 ENSG0000010000 Tgd 1584 G C chr20:1584:G:C -390102 0.8072535680703353 0.6040915863798888 0.44021249336515034 0.7178469713661249 +20 ENSG0000010000 Tgd 9078 T G chr20:9078:T:G -217794 0.5742591532812521 0.05320145532666787 0.23761188146279677 0.4976358135377754 +20 ENSG0000010000 Tgd 363 G A chr20:363:G:A 439358 0.34760310110916526 0.8675771482758895 -0.704239754918563 0.6823250029314895 +20 ENSG0000010000 Tgd 1072 A G chr20:1072:A:G -48242 0.7042178196040182 0.9427481527131556 0.9724131881631317 0.21598893537475924 +20 ENSG0000010000 Tgd 7408 C T chr20:7408:C:T 97538 0.798416345387464 0.5079549323489352 -0.18571600103031005 0.7665339498897865 +20 ENSG0000010000 Tgd 9616 C A chr20:9616:C:A 139206 0.052970921338451715 0.7544663202639632 0.17489534794812456 0.774846299330715 +20 ENSG0000010000 Tgd 1164 A G chr20:1164:A:G 265859 0.16120721945581085 0.1946189645588362 0.9595639050234177 0.7739604684715135 +20 ENSG0000010000 Tgd 2939 T A chr20:2939:T:A 180952 0.9288261793179441 0.7286671185456223 -0.3364197747542601 0.09506726668179767 +20 ENSG0000010000 Tgd 6612 T C chr20:6612:T:C -308122 0.09586329990025888 0.3551569519744139 0.41452590272368317 0.8791854674798408 +20 ENSG0000010000 Tgd 8187 A T chr20:8187:A:T -226841 0.40142775476431314 0.22664020472169422 0.9712720460776278 0.6333743185139211 +20 ENSG0000010000 Tgd 5566 G A chr20:5566:G:A 49314 0.25776782647073826 0.8793012619477467 -0.8781982215939446 0.5575712567648817 +20 ENSG0000010000 Tgd 29 C G chr20:29:C:G -178860 0.027653558552549473 0.905145045877089 0.12672940455132742 0.8594992655166971 +20 ENSG0000010000 Tgd 2825 T G chr20:2825:T:G -309383 0.5352139936266381 0.9757743727061745 -0.8060684372172193 0.683497902957365 +20 ENSG0000010000 Tgd 2535 C T chr20:2535:C:T 434739 0.4406975858387914 0.8459730586385126 0.543967219851792 0.5078213987328178 +20 ENSG0000010000 Tgd 7293 A C chr20:7293:A:C 480452 0.2914309435172 0.34905402126187124 -0.6391664804502379 0.5189703591184163 +20 ENSG0000010000 Tgd 1634 G T chr20:1634:G:T 132819 0.15525262055800781 0.6131916114687855 -0.3252066085067651 0.45521242374686793 +20 ENSG0000010000 Tgd 8979 C T chr20:8979:C:T -116543 0.14138137727567068 0.9603870646475665 -0.0184636982032631 0.7942599059185416 +20 ENSG0000010000 Tgd 682 C A chr20:682:C:A 461135 0.9823456326210844 0.4804233969070565 0.6872027353892931 0.66000036422856 +20 ENSG0000010000 Tgd 9686 C G chr20:9686:C:G 293691 0.5463811207055934 0.20093208761931625 -0.3593671599704673 0.4484566655588082 +20 ENSG0000010000 Tgd 3245 C G chr20:3245:C:G -76126 0.4351388244112353 0.08238888897348451 -0.9523316995614857 0.10521418345863352 +20 ENSG0000010000 Tgd 4706 T A chr20:4706:T:A -177962 0.8920925377865869 0.7478513859232987 0.14254982088188872 0.17418539934077482 +20 ENSG0000010000 Tgd 5139 A C chr20:5139:A:C -96402 0.18823901080910566 0.9641871119869029 -0.895129489544837 0.8255688612943977 +20 ENSG0000010000 Tgd 7108 T C chr20:7108:T:C 214220 0.6991831142062 0.9106621013171461 -0.8026985308940151 0.950014336880443 +20 ENSG0000010000 Tgd 3631 C A chr20:3631:C:A 248719 0.20360823344644308 0.2067369414206246 0.28084228356207963 0.016577116811190857 +20 ENSG0000010000 Tgd 6251 T A chr20:6251:T:A 469211 0.2904416770096032 0.9043957981496109 0.31918838342484435 0.9153297428523952 +20 ENSG0000010000 Tgd 5420 T G chr20:5420:T:G 366723 0.22837182411390367 0.9175836953355916 -0.1960825317389252 0.1567730637977104 +20 ENSG0000010000 Tgd 9810 T C chr20:9810:T:C 424786 0.9221777798447057 0.6803957191894928 0.4203448573312665 0.9021857245084958 +20 ENSG0000010000 Tgd 5075 T C chr20:5075:T:C -70920 0.6902812571095481 0.41588736939098625 -0.17272029255134225 0.2788085967882842 +20 ENSG0000010000 Tgd 3105 G C chr20:3105:G:C 129281 0.010429707367249463 0.6925231396814322 -0.916401301383946 0.7673594816526701 +20 ENSG0000010000 Tgd 2112 T A chr20:2112:T:A 168568 0.11438037540971036 0.15892383383376252 0.5823800934633137 0.06743381463121766 +20 ENSG0000010000 Tgd 8798 C T chr20:8798:C:T 489334 0.7400929425395962 0.9553172043033361 0.4300467510613697 0.6953242139801855 +20 ENSG0000010000 Tgd 4667 C A chr20:4667:C:A 297955 0.11940070535917757 0.8228774807274314 0.7680531174261287 0.9502588652924937 +20 ENSG0000010000 Tgd 9090 G T chr20:9090:G:T -366711 0.5182255580690388 0.03569518379089964 -0.04236042336607149 0.11229521939468702 +20 ENSG0000010000 Tgd 624 G T chr20:624:G:T -412331 0.762541411024457 0.8064091136112836 -0.5164963091023471 0.6157055060232505 +20 ENSG0000010000 Tgd 7178 T G chr20:7178:T:G 126001 0.7691265645701579 0.6628767619551389 0.0072385783015216365 0.9745330938755009 +20 ENSG0000010000 Tgd 3448 C A chr20:3448:C:A 96431 0.014211140189986038 0.15271052972486232 0.7189751111032723 0.2515513640114511 +20 ENSG0000010000 Tgd 2876 C G chr20:2876:C:G -289604 0.9015628147433338 0.05642815970861803 -0.23993131290230885 0.9468744681590333 +20 ENSG0000010000 Tgd 8284 A T chr20:8284:A:T -307101 0.6272136285479298 0.3358886290938572 0.44236216603028167 0.026284363809719474 +20 ENSG0000010000 Tgd 7218 A T chr20:7218:A:T 130886 0.5285566023573766 0.556853131660059 -0.7132730998527506 0.9642123614343703 +20 ENSG0000010000 Tgd 930 G A chr20:930:G:A 148634 0.720482462420428 0.7240793625474018 -0.35668748065274736 0.03939159126090246 +20 ENSG0000010000 Tgd 1701 T A chr20:1701:T:A -100269 0.003420953174767316 0.0584175423808847 -0.22494545923627274 0.5673878227585736 +20 ENSG0000010000 Tgd 3679 A G chr20:3679:A:G 482736 0.5714918721079092 0.3860547489111754 0.37121997201515855 0.3873803702832872 +20 ENSG0000010000 Tgd 3894 G C chr20:3894:G:C -138088 0.9801311044989338 0.63669757138926 -0.04174183429142064 0.8986781757398306 +20 ENSG0000010000 Tgd 7442 C T chr20:7442:C:T -348578 0.28686351058701576 0.7309785349246349 0.9260793770457805 0.3890633256147901 +20 ENSG0000010000 Tgd 4215 T C chr20:4215:T:C 275952 0.020937125621263486 0.8054504789401417 -0.7120324515915679 0.4604721374881347 +20 ENSG0000010000 Tgd 8872 T G chr20:8872:T:G -368903 0.8401353480406099 0.35294137305096474 0.8837621868519836 0.42171951435311256 +20 ENSG0000010000 Tgd 6845 G C chr20:6845:G:C -145790 0.3260109846694277 0.3988830606126388 0.44661542072797955 0.206709165273317 +20 ENSG0000010000 Tgd 3555 C G chr20:3555:C:G 74835 0.8624386844335241 0.7920783043519265 -0.2503667228817934 0.3075920839406562 +20 ENSG0000010000 Tgd 6437 T G chr20:6437:T:G -386073 0.5428287062960672 0.4523198105418702 0.8093521272076352 0.9557771102473368 +20 ENSG0000010000 Tgd 6753 A T chr20:6753:A:T -272273 0.3376831527925511 0.8899246540421198 0.3193029222531689 0.9371848543210577 +20 ENSG0000010000 Tgd 7075 T G chr20:7075:T:G -475007 0.6939696088914072 0.3859706712319918 0.33398707467825384 0.2740466618884274 +20 ENSG0000010000 Tgd 9231 T G chr20:9231:T:G 103003 0.7818589121165633 0.19780974947425167 -0.17742053692801774 0.46911118375102256 +20 ENSG0000010000 Tgd 2140 G C chr20:2140:G:C 140006 0.9330202174439476 0.6123248974277683 0.4706352446688058 0.8760406541173631 +20 ENSG0000010000 Tgd 1591 A C chr20:1591:A:C 394016 0.08994697267781104 0.9315626464918535 -0.2866072922496936 0.743840721863898 +20 ENSG0000010000 Tgd 3490 C A chr20:3490:C:A -119430 0.6232316859755337 0.31550003277844574 0.8090302918591277 0.44717040867069546 +20 ENSG0000010000 Tgd 5548 T C chr20:5548:T:C -182030 0.10149948896717964 0.5618875560150474 0.8016341161811549 0.15286487735132484 +20 ENSG0000010000 Tgd 6803 A G chr20:6803:A:G -334031 0.5616640713238805 0.6286824902114844 0.3997252282992454 0.2819533776288758 +20 ENSG0000010000 Tgd 4087 A T chr20:4087:A:T 453349 0.4449038885315427 0.7556735131098207 -0.7288025188411504 0.381568193974646 +20 ENSG0000010000 Tgd 6216 G T chr20:6216:G:T 304402 0.019954119519705826 0.6881214975399751 0.6359034085629018 0.9310112388766972 +20 ENSG0000010000 Tgd 9583 T G chr20:9583:T:G 437414 0.01985666878742498 0.49176703353676254 0.3435234511909335 0.3444849900209774 +20 ENSG0000010000 Tgd 5567 A C chr20:5567:A:C -427764 0.17723547022747543 0.6240310989328066 0.35474631776833143 0.9168472431252637 +20 ENSG0000010000 Tgd 1819 T C chr20:1819:T:C -193450 0.7114081814347346 0.9487617744995449 -0.8338546104027056 0.6032097457318554 +20 ENSG0000010000 Tgd 8106 A G chr20:8106:A:G -322728 0.36521597840825337 0.2527157753111656 0.0268455934561167 0.9820543568947253 +20 ENSG0000010000 Tgd 385 G C chr20:385:G:C 449817 0.1668819192946781 0.649405116131931 0.4010297701751606 0.26385027688355833 +20 ENSG0000010000 Tgd 7094 C A chr20:7094:C:A -213911 0.749997623228257 0.7597650636486216 -0.08382495255156575 0.0811639418347622 +20 ENSG0000010000 Tgd 9033 A T chr20:9033:A:T 414400 0.9782486626993503 0.624169655223771 0.4692825313456743 0.020192946630774054 +20 ENSG0000010000 Tgd 6237 T G chr20:6237:T:G -101524 0.38839713510858376 0.6952882831685536 -0.4594326213470685 0.3757668164543753 +20 ENSG0000010000 Tgd 6010 C T chr20:6010:C:T 488708 0.34623909532366026 0.26158793682145065 -0.6141931341762779 0.28235949398134536 +20 ENSG0000010000 Tgd 1365 G A chr20:1365:G:A 344601 0.6662225940327472 0.318613923054033 0.017582563993620015 0.1144117463155422 +20 ENSG0000010000 Tgd 2106 A T chr20:2106:A:T -421971 0.1771072177096329 0.0649591695815781 0.1438176155307449 0.23770838411970288 +20 ENSG0000010000 Tgd 1432 A C chr20:1432:A:C 412428 0.9089114264954676 0.07038277504029711 0.1655098293144459 0.965678691942081 +20 ENSG0000010000 Tgd 7550 C A chr20:7550:C:A 142321 0.12197839510564812 0.7041476304733376 -0.6009573799669421 0.7463180171596658 +20 ENSG0000010000 Tgd 1330 T A chr20:1330:T:A 253144 0.9513919211297178 0.00384113515145601 0.5831854594588428 0.23384267122305052 +20 ENSG0000010000 Tgd 820 A G chr20:820:A:G -164032 0.6254517400960138 0.19263858702811676 0.6351018577411733 0.7085293879430118 +20 ENSG0000010000 Tgd 8116 T G chr20:8116:T:G -197944 0.7315647428941676 0.5918120508269088 0.7217978546212067 0.4430738119538345 +20 ENSG0000010000 Tgd 8317 C T chr20:8317:C:T 420834 0.5419984353738582 0.9727237164180397 0.3999340403677567 0.70316522665996 +20 ENSG0000010000 Tgd 1242 C T chr20:1242:C:T -329687 0.3946679728872844 0.836040404381664 -0.40656100807258544 0.41286970438918313 +20 ENSG0000010000 Tgd 4677 T G chr20:4677:T:G -236861 0.8244685705360698 0.7354431542811594 0.06110169003878618 0.6551873251100295 +20 ENSG0000010000 Tgd 4124 C T chr20:4124:C:T -432207 0.06161957280921171 0.49392304825949107 0.805386926724228 0.06134357350487657 +20 ENSG0000010000 Tgd 7047 A G chr20:7047:A:G -487419 0.9771676640530578 0.6745011217015362 -0.3632039042094557 0.7716147225604731 +20 ENSG0000010000 Tgd 5228 G C chr20:5228:G:C 278245 0.8109653702411711 0.37044339254271186 -0.3995056485621262 0.4895983698529094 +20 ENSG0000010000 Tgd 8945 T A chr20:8945:T:A 224424 0.352894964886698 0.4649448162315387 -0.07671956234622357 0.9235225744355872 +20 ENSG0000010000 Tgd 6607 G T chr20:6607:G:T -351016 0.7378591951023942 0.3855641664534595 0.8992682102990122 0.8734883981666907 +20 ENSG0000010000 Tgd 5190 G T chr20:5190:G:T -81180 0.36571004997156675 0.4343812673641376 0.634809593286694 0.9054569470033583 +20 ENSG0000010000 Tgd 2475 T C chr20:2475:T:C -146300 0.1977564843124201 0.49732243561917466 -0.6833673223328274 0.8299483861270589 +20 ENSG0000010000 Tgd 9001 C T chr20:9001:C:T -300828 0.4865347713740542 0.723729204380042 -0.13428751475948753 0.9473835600893609 +20 ENSG0000010000 Tgd 2619 G A chr20:2619:G:A -129466 0.9614394166023396 0.06690607929937775 -0.35343499919736243 0.47722355061180766 +20 ENSG0000010000 Tgd 4741 G T chr20:4741:G:T -63431 0.49050687263136794 0.9568567149937725 0.2630172097474692 0.3392419282483203 +20 ENSG0000010000 Tgd 5090 G A chr20:5090:G:A 128218 0.12942807770994835 0.28189712271911826 0.4495135005318327 0.8073171602847127 +20 ENSG0000010000 Tgd 2100 C G chr20:2100:C:G -433809 0.01770978754072039 0.3700085164383097 -0.5077802954695227 0.9446321733957113 +20 ENSG0000010000 Tgd 3825 C G chr20:3825:C:G 325026 0.28053134348240305 0.3407573370428367 0.5876360286930309 0.6986312174587204 +20 ENSG0000010000 Tgd 2083 C T chr20:2083:C:T 242501 0.5928347826703423 0.2370178760090611 0.6393139697477082 0.4890993321741724 +20 ENSG0000010000 Tgd 7697 A C chr20:7697:A:C 35780 0.8807281635372538 0.38414334319675203 -0.7032890822945983 0.32233327638526527 +20 ENSG0000010000 Tgd 8671 C A chr20:8671:C:A -28681 0.38957647813434315 0.19318172180117343 0.5398913812072628 0.7121957111950239 +20 ENSG0000010000 Tgd 5961 A G chr20:5961:A:G -241437 0.22333331877790252 0.0030532280148146684 -0.2876624491090063 0.6210318702390086 +20 ENSG0000010000 Tgd 9206 T C chr20:9206:T:C -164419 0.48469771433833664 0.3141682789085136 0.7664270033882583 0.2008582813763045 +20 ENSG0000010000 Tgd 3084 A C chr20:3084:A:C 269046 0.06056295138221135 0.884771691225045 0.04700438378525518 0.5046251187337473 +20 ENSG0000010000 Tgd 4067 A C chr20:4067:A:C -226335 0.20424002516314088 0.2961033733582772 -0.9423575304204976 0.6443442914382461 +20 ENSG0000010000 Tgd 6905 A C chr20:6905:A:C -12476 0.7757969044879571 0.9929797511370088 -0.10662980935141642 0.38263743743083695 +20 ENSG0000010000 Tgd 2572 G C chr20:2572:G:C -387022 0.9369029795643095 0.4559432363208342 -0.6044386222020279 0.606935928977133 +20 ENSG0000010000 Tgd 4666 C A chr20:4666:C:A -370066 0.0524234836380012 0.3265380379004412 -0.045796969997555115 0.1426110885959376 +20 ENSG0000010000 Tgd 6145 A G chr20:6145:A:G 177724 0.32388422932876415 0.17799843346037314 0.22616411501278444 0.7607709687389392 +20 ENSG0000010000 Tgd 4636 C A chr20:4636:C:A 426164 0.5117083717574118 0.7227766716276871 0.4273282458166294 0.49717993278662875 +20 ENSG0000010000 Tgd 1113 A T chr20:1113:A:T 485790 0.7138537931070744 0.09185940589502128 -0.2793661360097017 0.3577239547730974 +20 ENSG0000010000 Tgd 1330 G C chr20:1330:G:C 287324 0.06957652786713608 0.40055987645023594 -0.8756990950602392 0.4169365646479792 +20 ENSG0000010000 Tgd 6488 T A chr20:6488:T:A 353922 0.20725456959380317 0.15906045671738045 0.5255281464967783 0.8687963913268889 +20 ENSG0000010000 Tgd 3726 T A chr20:3726:T:A 176078 0.6835219380087001 0.02422519812347812 0.2858051187231119 0.6975904820359822 +20 ENSG0000010000 Tgd 7843 A C chr20:7843:A:C 16137 0.02351313583286152 0.7147421739781256 -0.17012257054401814 0.06889357511021114 +20 ENSG0000010000 Tgd 3279 A T chr20:3279:A:T -259346 0.5827391854782779 0.007152373711627136 0.4036484223697696 0.582001632688681 +20 ENSG0000010000 Tgd 6032 T G chr20:6032:T:G -276886 0.1522558520453422 0.007349944972996791 0.2553595862426443 0.6231690593222956 +20 ENSG0000010000 Tgd 4353 C G chr20:4353:C:G -332372 0.834822343301668 0.7541714728446194 -0.48744354643693955 0.19657666179337366 +20 ENSG0000010000 Tgd 4266 G A chr20:4266:G:A 182059 0.2853817302856577 0.02881747816162883 0.206735714789253 0.6517572091160306 +20 ENSG0000010000 Tgd 3029 G A chr20:3029:G:A 278896 0.9330835407542759 0.205583186448683 0.5195185627074088 0.7359668251389694 +20 ENSG0000010000 Tgd 4893 T C chr20:4893:T:C -121529 0.46377977024292605 0.6478300886311951 -0.5403799032144758 0.8903163084126714 +20 ENSG0000010000 Tgd 4135 T A chr20:4135:T:A -175045 0.012360336008843342 0.8295871926912601 0.7207160194804074 0.20714634684542652 +20 ENSG0000010000 Tgd 6367 C G chr20:6367:C:G -90265 0.601812979235192 0.16525728941573903 -0.016635485288864826 0.5612690375308963 +20 ENSG0000010000 Tgd 4676 T A chr20:4676:T:A 146311 0.10726158979842326 0.00027073810012190336 -0.9376001265752802 0.050978011900997246 +20 ENSG0000010000 Tgd 184 C A chr20:184:C:A -181814 0.44506061361298643 0.7287482289084114 0.9224167936963914 0.09813543732080082 +20 ENSG0000010000 Tgd 6031 G C chr20:6031:G:C -420204 0.27997868074094523 0.653625972735841 -0.405060145699327 0.03595776094960548 +20 ENSG0000010000 Tgd 1968 C T chr20:1968:C:T -224513 0.456927649156196 0.9322456411075738 0.9665661275469768 0.9146514978517688 +20 ENSG0000010000 Tgd 1972 A G chr20:1972:A:G -316939 0.014344037417968858 0.08609527144438789 -0.5303943536394153 0.8699219982069251 +20 ENSG0000010000 Tgd 9500 A G chr20:9500:A:G -433643 0.731434022574138 0.15329485547151844 -0.8696844667563002 0.6783412463966577 +20 ENSG0000010000 Tgd 490 A G chr20:490:A:G -46504 0.8304512162931381 0.4124242527412093 0.9458142371962823 0.5771839254834555 +20 ENSG0000010000 Tgd 722 A C chr20:722:A:C 244385 0.28156860708349074 0.47917118074520393 0.603882033635444 0.02538846253284296 +20 ENSG0000010000 Tgd 4456 G A chr20:4456:G:A 181765 0.04412310476244152 0.5632119688048398 0.7139964317581726 0.559385451921778 +20 ENSG0000010000 Tgd 8005 T A chr20:8005:T:A -199566 0.3640347949297428 0.5980490771479692 -0.0874850329650314 0.47300270741467293 +20 ENSG0000010000 Tgd 2686 T C chr20:2686:T:C 270907 0.6393141846864502 0.4070016456690634 0.1604235828187941 0.3727378059030822 +20 ENSG0000010000 Tgd 5693 C T chr20:5693:C:T 353779 0.6726579424117447 0.8894290811904569 0.3514213940839259 0.4084179523510375 +20 ENSG0000010000 Tgd 7074 A C chr20:7074:A:C 427751 0.13764149198535136 0.9247190755506507 0.29092828134529536 0.4513179758559883 +20 ENSG0000010000 Tgd 8835 T A chr20:8835:T:A -139863 0.5063528784982761 0.859711542596773 0.25012561895028473 0.5991937554948644 +20 ENSG0000010000 Tgd 1340 G A chr20:1340:G:A 25738 0.5439967367200436 0.5195688464031764 0.1509291828280761 0.2554624460903611 +20 ENSG0000010000 Tgd 9019 C G chr20:9019:C:G -377400 0.3254872987557552 0.8364687844880893 -0.2533557482294635 0.9369911385071691 +20 ENSG0000010000 Tgd 9454 C G chr20:9454:C:G 221211 0.7515655159052504 0.10642662812631432 0.28093869453522946 0.45420043515075353 +20 ENSG0000010000 Tgd 3086 G T chr20:3086:G:T 460331 0.07220667373342349 0.9501106016826326 -0.5163333005338824 0.40671375054534326 +20 ENSG0000010000 Tgd 3429 A T chr20:3429:A:T -475353 0.016219996147583737 0.2957840719899202 -0.5858252020818873 0.8278289460785074 +20 ENSG0000010000 Tgd 1169 A C chr20:1169:A:C -25416 0.9510126569789121 0.421917527503331 -0.28497142103932727 0.40359780852167215 +20 ENSG0000010000 Tgd 9791 G C chr20:9791:G:C -281427 0.303786608789294 0.6192577748722642 0.8391113799577874 0.6355843813060847 +20 ENSG0000010000 Tgd 9722 A G chr20:9722:A:G -466951 0.49999484657966975 0.3514969574737572 -0.48843564539206774 0.47412389077479905 +20 ENSG0000010000 Tgd 6288 A G chr20:6288:A:G 222040 0.5871247173863032 0.8806357484389462 0.8982446189427724 0.6851633224846284 +20 ENSG0000010000 Tgd 448 G A chr20:448:G:A 11126 0.7590494744917409 0.08682862277978498 -0.49568723822034966 0.092956790513409 +20 ENSG0000010000 Tgd 4021 A G chr20:4021:A:G -101698 0.7490522216065428 0.24137863966531103 0.9680004934859201 0.035307807665688036 +20 ENSG0000010000 Tgd 5076 G T chr20:5076:G:T 143529 0.4106070927899611 0.01029395076501205 -0.7432316900278768 0.8628539705989319 +20 ENSG0000010000 Tgd 463 G A chr20:463:G:A 26461 0.18123327540740353 0.27474114818223594 0.13009991330173754 0.8015063699860534 +20 ENSG0000010000 Tgd 8777 A C chr20:8777:A:C 114110 0.11766856683952032 0.5167363248102292 -0.6521626427432636 0.4522742062292701 +20 ENSG0000010000 Tgd 2667 A C chr20:2667:A:C 130320 0.3314156042540938 0.10967457061117403 -0.6904076193486934 0.8375370600129949 +20 ENSG0000010000 Tgd 3263 T A chr20:3263:T:A -93883 0.7757401149312464 0.8068026576479638 0.810819926509732 0.7726902061726368 +20 ENSG0000010000 Tgd 719 C T chr20:719:C:T -265725 0.34007041056130516 0.6830331354109184 0.691076837380991 0.22950379164601944 +20 ENSG0000010000 Tgd 7286 T A chr20:7286:T:A -40622 0.4961456609269651 0.7943373523572176 -0.14005307822618485 0.7087003978539261 +20 ENSG0000010000 Tgd 6035 A G chr20:6035:A:G -3334 0.03353686093466135 0.43629112509847845 0.4040955219008808 0.06787161121599498 +20 ENSG0000010000 Tgd 1430 T A chr20:1430:T:A 98129 0.1867907171297144 0.19651704613940502 0.31972393388331577 0.5463729732330407 +20 ENSG0000010000 Tgd 9132 C G chr20:9132:C:G -429936 0.9708653747290236 0.6562626971714957 0.16424102206909308 0.11673397710253974 +20 ENSG0000010000 Tgd 652 T C chr20:652:T:C -360315 0.7466421477606437 0.39070975788826956 -0.25628288000831034 0.5106858325324878 +20 ENSG0000010000 Tgd 200 A C chr20:200:A:C 114017 0.5305192992751113 0.30334414452600955 0.6229234805265336 0.3202096683219889 +20 ENSG0000010000 Tgd 3993 G T chr20:3993:G:T -302169 0.6640363519993391 0.4782754367495652 -0.5717550203346162 0.17324555342994383 +20 ENSG0000010000 Tgd 9061 A T chr20:9061:A:T 199486 0.12695558263246431 0.5098678927526072 0.7223709487992229 0.06892602297075613 +20 ENSG0000010000 Tgd 8412 A T chr20:8412:A:T -240931 0.6269409414635132 0.4135086226446252 0.2512469941634312 0.9376709406384579 +20 ENSG0000010000 Tgd 4301 G A chr20:4301:G:A 288918 0.43187103452465603 0.8706687265670864 0.5612639992628818 0.02863757130066368 +20 ENSG0000010000 Tgd 6123 C G chr20:6123:C:G 310653 0.07505540872172656 0.599821783832565 -0.16536712547639065 0.5621249862295226 +20 ENSG0000010000 Tgd 4545 G C chr20:4545:G:C -12930 0.6501668602735652 0.9866789051675108 -0.31703473175321695 0.8364881477710281 +20 ENSG0000010000 Tgd 9918 G T chr20:9918:G:T -7874 0.3370752564891255 0.6914240754371548 0.9504533014060559 0.5332063750287933 +20 ENSG0000010000 Tgd 1032 T C chr20:1032:T:C 471841 0.9058108204913463 0.9072176310376434 0.13202984916070948 0.34916470235860597 +20 ENSG0000010000 Tgd 5020 T C chr20:5020:T:C 42818 0.6761001155640128 0.2785221357934933 0.19552101826441448 0.6700149389986099 +20 ENSG0000010000 Tgd 3086 T C chr20:3086:T:C -300807 0.68710338090345 0.3614869394348639 0.0855518363848804 0.3218213462625445 +20 ENSG0000010000 Tgd 7581 T A chr20:7581:T:A 259790 0.7227425417016868 0.29146111487295745 -0.5059457390646067 0.5985331140544644 +20 ENSG0000010000 Tgd 5528 T G chr20:5528:T:G -106786 0.2456338136764633 0.4843433180230964 -0.45851901274198426 0.5686211965875339 +20 ENSG0000010000 Tgd 8805 C T chr20:8805:C:T -232901 0.6059837570194173 0.2525356942745244 0.9330274071777167 0.8133014134625548 +20 ENSG0000010000 Tgd 6441 T C chr20:6441:T:C 472874 0.49505560438901597 0.9347510188136529 0.10128837203358998 0.8213370815799725 +20 ENSG0000010000 Tgd 8375 G T chr20:8375:G:T -221393 0.05099304006679084 0.4277072968193346 0.9633933229678808 0.595676502667152 +20 ENSG0000010000 Tgd 7805 C A chr20:7805:C:A -353486 0.18110472800520505 0.3613349330434532 0.6025995760290321 0.055447642616879754 +20 ENSG0000010000 Tgd 1152 C A chr20:1152:C:A 75134 0.5352226366729609 0.12742211508654533 -0.8082187484838397 0.7432801018583591 +20 ENSG0000010000 Tgd 6935 T A chr20:6935:T:A 434607 0.6602969509852479 0.05987988419723578 -0.7771359184741098 0.9768594250733826 +20 ENSG0000010000 Tgd 4542 C G chr20:4542:C:G -247629 0.23048833176819683 0.6183119014178312 0.14123420047352542 0.26746904094460366 +20 ENSG0000010000 Tgd 9055 C T chr20:9055:C:T -340928 0.02295406575285075 0.5841200077289178 0.5247024479489371 0.17267049287188493 +20 ENSG0000010000 Tgd 6280 T A chr20:6280:T:A -331813 0.09117775090962843 0.7404561088542063 0.9573449935627878 0.27045942919508204 +20 ENSG0000010000 Tgd 7967 T G chr20:7967:T:G -268293 0.24202450707187206 0.6096072060290169 0.7837703551879986 0.9177079076626992 +20 ENSG0000010000 Tgd 4579 T C chr20:4579:T:C -43667 0.5796375711328927 0.5997163344144042 -0.2265934132610976 0.21417442361227088 +20 ENSG0000010000 Tgd 7277 G T chr20:7277:G:T 275070 0.8881184114849233 0.8505863816667565 0.5013883617544566 0.024003563022042394 +20 ENSG0000010000 Tgd 4452 T G chr20:4452:T:G -42139 0.789587757551273 0.5239353801480586 -0.3558399674189716 0.49953311885931917 +20 ENSG0000010000 Tgd 6356 G T chr20:6356:G:T -108922 0.14451573568177511 0.07735695392603825 0.6738794997174864 0.6835951657987133 +20 ENSG0000010000 Tgd 2759 G T chr20:2759:G:T -271486 0.31421178097475677 0.40510228480504273 -0.5024686796228024 0.29138813448365136 +20 ENSG0000010000 Tgd 3783 A T chr20:3783:A:T 176831 0.697580911701135 0.4522458070000236 0.600201279250969 0.3894810085600976 +20 ENSG0000010000 Tgd 5656 C G chr20:5656:C:G -478511 0.4909574719987202 0.7241784888902869 0.8183760706206831 0.09037144426945583 +20 ENSG0000010000 Tgd 4177 C T chr20:4177:C:T -217806 0.36659475350080906 0.9970990811277858 -0.04293849828692986 0.16937311492053883 +20 ENSG0000010000 Tgd 9593 T A chr20:9593:T:A -100027 0.364571839928467 0.7607102411134554 -0.8200549973978917 0.915934067901931 +20 ENSG0000010000 Tgd 1514 A C chr20:1514:A:C -416895 0.5252538690865791 0.25514532963261627 -0.7019413218922494 0.14249240448804007 +20 ENSG0000010000 Tgd 7142 C T chr20:7142:C:T -259784 0.40946437650619705 0.16662879676005216 -0.8664422000674066 0.8719382990015946 +20 ENSG0000010000 Tgd 855 T C chr20:855:T:C 74555 0.4702483634800918 0.4232640109577924 -0.6641475672089276 0.018164630472071425 +20 ENSG0000010000 Tgd 3202 A C chr20:3202:A:C 356990 0.7831435887420967 0.533953324885199 0.5581186333676744 0.5538852155961053 +20 ENSG0000010000 Tgd 6045 A C chr20:6045:A:C 396959 0.1717945468898835 0.2723374479505859 0.6266115310895137 0.5014121742248924 +20 ENSG0000010000 Tgd 932 G T chr20:932:G:T -324887 0.04834446660479075 0.15590941046578521 -0.7354180329751141 0.8618266023126254 +20 ENSG0000010000 Tgd 6017 C G chr20:6017:C:G -242272 0.45494415741521865 0.7102091842135502 0.42685938251338595 0.162924814466357 +20 ENSG0000010000 Tgd 9929 G T chr20:9929:G:T -499399 0.28720249578932444 0.5288930520328734 -0.02008696380964814 0.7545042802067242 +20 ENSG0000010000 Tgd 9017 C G chr20:9017:C:G 288142 0.2514298150201917 0.9368701086020342 -0.666208945167772 0.8580689075382574 +20 ENSG0000010000 Tgd 2069 A T chr20:2069:A:T -423017 0.5997982173764302 0.36750126512308423 -0.4031156433293792 0.6047913581673877 +20 ENSG0000010000 Tgd 6757 A C chr20:6757:A:C 10888 0.19870284758740198 0.01604154121555701 -0.12892492450666349 0.6388152217611458 +20 ENSG0000010000 Tgd 2412 G T chr20:2412:G:T 180600 0.7937605254499028 0.3963607716895027 -0.7153693435135777 0.90060307391617 +20 ENSG0000010000 Tgd 7194 C G chr20:7194:C:G -81368 0.4663490482635071 0.4652047035959893 0.7647668749793233 0.4638360059133447 +20 ENSG0000010000 Tgd 6813 A T chr20:6813:A:T 493762 0.1455374724942361 0.6400228733028972 -0.7974303171721386 0.37466160630484086 +20 ENSG0000010000 Tgd 5744 G A chr20:5744:G:A 127296 0.2939510371891735 0.82109421873511 0.10321345146161454 0.04148389076473709 +20 ENSG0000010000 Tgd 7856 A C chr20:7856:A:C -152447 0.19347930185751439 0.9219852872693356 -0.6681092081806634 0.9921074619904267 +20 ENSG0000010000 Tgd 2392 C A chr20:2392:C:A -474118 0.5095067040524914 0.6306745076260792 -0.2574671354272986 0.4489102993235635 +20 ENSG0000010000 Tgd 5473 G C chr20:5473:G:C 151975 0.32654466692303985 0.36796753146437067 0.6024479198008406 0.5860355430034883 +20 ENSG0000010000 Tgd 7183 T G chr20:7183:T:G -153811 0.6606162616183695 0.4398614595193403 0.44508703999526333 0.26783874282097464 +20 ENSG0000010000 Tgd 2330 T A chr20:2330:T:A 146839 0.38388953563392025 0.39439940616665436 -0.9162167006132989 0.3036073804579869 +20 ENSG0000010000 Tgd 2179 T G chr20:2179:T:G 96948 0.1936642558693069 0.799471667602078 0.766333194846607 0.4274845807590254 +20 ENSG0000010000 Tgd 9310 C T chr20:9310:C:T -499406 0.9910264988707621 0.1633914400550771 -0.925078015543406 0.7275106980441652 +20 ENSG0000010000 Tgd 1083 T G chr20:1083:T:G 459587 0.9811972690046126 0.9248217841432377 -0.013035534110113822 0.08088956079444073 +20 ENSG0000010000 Tgd 7531 G C chr20:7531:G:C 105073 0.5585685860211056 0.8891703032055938 0.6287608555273911 0.3312692641980424 +20 ENSG0000010000 Tgd 5350 T C chr20:5350:T:C 345350 0.5938503204159148 0.8965901229180138 -0.5476022092263124 0.023202971715029195 +20 ENSG0000010000 Tgd 7920 C G chr20:7920:C:G 259459 0.9913129017107866 0.05128657037094564 0.1833856895617021 0.8018721249346642 +20 ENSG0000010000 Tgd 4222 A T chr20:4222:A:T 81974 0.22362521174913785 0.7834764511805218 0.7614923113014815 0.24948927865090387 +20 ENSG0000010000 Tgd 2511 A C chr20:2511:A:C -67311 0.7425235688675247 0.4192915303004746 -0.33757373244934485 0.082048073360709 +20 ENSG0000010000 Tgd 2662 G A chr20:2662:G:A 312610 0.31395700518879666 0.8893065009780454 -0.12875314942114513 0.8152457739914621 +20 ENSG0000010000 Tgd 2524 A C chr20:2524:A:C 483138 0.37038009701837893 0.3080074134147339 -0.026960076703044233 0.9978007224900194 +20 ENSG0000010000 Tgd 6494 T G chr20:6494:T:G -49002 0.8494500609868119 0.28646759125021004 0.2211454481561408 0.165729532456213 +20 ENSG0000010000 Tgd 2609 C G chr20:2609:C:G 394643 0.08287837431326384 0.08209486367039565 0.5923885961984128 0.009481373339118047 +20 ENSG0000010000 Tgd 8854 A T chr20:8854:A:T -446148 0.0020872613132606466 0.17757307017359603 -0.7330333994116929 0.9837173629532472 +20 ENSG0000010000 Tgd 6010 C A chr20:6010:C:A -457607 0.1652215636736134 0.30976739026711686 -0.8000573808112408 0.9963192202395248 +20 ENSG0000010000 Tgd 1350 A C chr20:1350:A:C 122193 0.2914284364539018 0.8368498275137506 -0.85663338256177 0.6131242278900773 +20 ENSG0000010000 Tgd 2272 A G chr20:2272:A:G 135612 0.8523954395948515 0.15739404144483815 0.5521503344169665 0.5153765623496775 +20 ENSG0000010000 Tgd 8134 T C chr20:8134:T:C -466411 0.39339347818610393 0.3386576076225085 -0.6743869677944665 0.4731876488436797 +20 ENSG0000010000 Tgd 7414 C G chr20:7414:C:G -61728 0.8069658646769605 0.23512508566869417 0.9691973454821534 0.31001676878772005 +20 ENSG0000010000 Tgd 5352 G T chr20:5352:G:T 237394 0.15521907833812865 0.07945312603375376 0.17536619119557173 0.11860042076209404 +20 ENSG0000010000 Tgd 1765 G T chr20:1765:G:T -343420 0.7227697303402584 0.2824752611694239 -0.33454357552936975 0.32063044080653064 +20 ENSG0000010000 Tgd 3920 G A chr20:3920:G:A 475042 0.6443110232671301 0.9425787305209091 0.1042404730525679 0.5880831270757575 +20 ENSG0000010000 Tgd 3437 G A chr20:3437:G:A -118099 0.15653095685537366 0.19148860383842614 -0.8678892992598983 0.032348132746519334 +20 ENSG0000010000 Tgd 4132 G T chr20:4132:G:T 351987 0.4976169277988668 0.6583294493448177 -0.20502072894983336 0.7094325885080682 +20 ENSG0000010000 Tgd 5302 G T chr20:5302:G:T 355408 0.326908184180269 0.9666971169962326 -0.15530320020906907 0.3154735900842178 +20 ENSG0000010000 Tgd 9283 T A chr20:9283:T:A 411395 0.7832066801501745 0.954289572317901 -0.16839793185567364 0.4874073100808667 +20 ENSG0000010000 Tgd 5482 T A chr20:5482:T:A 427170 0.14034098565595876 0.5127844110423463 -0.009284705563446849 0.2785844474092095 +20 ENSG0000010000 Tgd 3314 T G chr20:3314:T:G -459684 0.7708599419089044 0.6315379616672361 0.42273043607120186 0.800408416682944 +20 ENSG0000010000 Tgd 6112 C A chr20:6112:C:A -390322 0.48279836603677284 0.8243240413760697 0.002153787042397548 0.2118507001225504 +20 ENSG0000010000 Tgd 5448 C G chr20:5448:C:G 432798 0.5287351607801845 0.59048779765117 0.8531564565334395 0.1974643526114726 +20 ENSG0000010000 Tgd 646 G C chr20:646:G:C 64964 0.9967901166958628 0.4564363661744718 -0.4310286591558843 0.018896986826724995 +20 ENSG0000010000 Tgd 9656 A G chr20:9656:A:G 369849 0.8782343746516489 0.9290484075512221 0.8282104117329092 0.6091516975635718 +20 ENSG0000010000 Tgd 3784 C T chr20:3784:C:T -28905 0.2647005043944902 0.8915131960217259 0.7043294465349683 0.8169195314589399 +20 ENSG0000010000 Tgd 9496 C G chr20:9496:C:G -221744 0.004285019120147893 0.229220845107318 -0.5563981242178593 0.8216856223106435 +20 ENSG0000010000 Tgd 3916 G A chr20:3916:G:A -49102 0.04776375709949021 0.07610571237199881 0.6065676253085539 0.5357223784820008 +20 ENSG0000010000 Tgd 8955 G A chr20:8955:G:A 26124 0.8685459267541561 0.7327500938969084 0.5335584974291867 0.7882058418683552 +20 ENSG0000010000 Tgd 9835 A G chr20:9835:A:G 108358 0.21341455380685626 0.661288585903937 -0.4248857232976735 0.11675578767343345 +20 ENSG0000010000 Tgd 3848 G C chr20:3848:G:C -314154 0.5450632546551714 0.20025707791903125 0.3701680813655328 0.08059721444134452 +20 ENSG0000010000 Tgd 4024 G A chr20:4024:G:A -395709 0.12987747737081323 0.7494102472887678 -0.4836135630455223 0.6577997104303859 +20 ENSG0000010000 Tgd 4213 G T chr20:4213:G:T 449962 0.4264493897862235 0.7291617927246339 -0.27714075002663874 0.7653276075110563 +20 ENSG0000010000 Tgd 4732 C A chr20:4732:C:A -420072 0.982813605335121 0.8732211598861283 0.7060605725214304 0.004324890491604319 +20 ENSG0000010000 Tgd 3925 A C chr20:3925:A:C -312336 0.11337075952366205 0.45129159344382463 -0.7571219131281515 0.7662337929856486 +20 ENSG0000010000 Tgd 8759 G A chr20:8759:G:A 4618 0.6679983780858367 0.2783005668632462 -0.8334637976250194 0.7892110275398051 +20 ENSG0000010000 Tgd 5788 T G chr20:5788:T:G 345783 0.1893001611925993 0.9449407178929143 0.4506304862831165 0.9110090139356701 +20 ENSG0000010000 Tgd 1416 A T chr20:1416:A:T -347105 0.3421011877085255 0.5220867083610441 0.37905960581912423 0.19497627087840178 +20 ENSG0000010000 Tgd 5758 A C chr20:5758:A:C 394966 0.3892782091547944 0.7567563163668033 -0.7928612260926511 0.512907331355559 +20 ENSG0000010000 Tgd 6594 T G chr20:6594:T:G 311035 0.5863544773141618 0.6973546897389036 0.9522745310220455 0.7449066084215376 +20 ENSG0000010000 Tgd 8100 T A chr20:8100:T:A -461854 0.4529094188517371 0.003721740625346359 -0.2891570774149699 0.9876747324311409 +20 ENSG0000010000 Tgd 6104 C G chr20:6104:C:G 286151 0.8375191167551115 0.9695837297675771 0.724013693086524 0.08614003748406117 +20 ENSG0000010000 Tgd 7757 G C chr20:7757:G:C -374430 0.6249465481253661 0.03248009671379781 0.6704534238290829 0.31774984280609736 +20 ENSG0000010000 Tgd 5113 G C chr20:5113:G:C -459170 0.8586569138361084 0.0549130062688038 -0.39958976708615346 0.964113923664426 +20 ENSG0000010000 Tgd 2244 C G chr20:2244:C:G -339530 0.2806680823858171 0.8497369990649061 0.9626205276608055 0.9751544265853714 +20 ENSG0000010000 Tgd 5053 C G chr20:5053:C:G -476164 0.026147782662912178 0.28515521681125344 -0.6304477049142077 0.09398317422446147 +20 ENSG0000010000 Tgd 2252 A C chr20:2252:A:C -381119 0.09515726547419345 0.26419985121487655 -0.332429687405948 0.8885199777528885 +20 ENSG0000010000 Tgd 2993 T A chr20:2993:T:A -257235 0.0490787049868322 0.3114885228981613 0.5212688230009135 0.7550857907143609 +20 ENSG0000010000 Tgd 1306 A G chr20:1306:A:G 288845 0.9307873550112353 0.3118921959313624 0.7559285375501388 0.09387451039433185 +20 ENSG0000010000 Tgd 5461 C A chr20:5461:C:A -356459 0.06874755095180096 0.9489838253311518 0.17660851782574416 0.10772186752044381 +20 ENSG0000010000 Tgd 7815 A G chr20:7815:A:G 348822 0.3611281991451135 0.5419644125319342 -0.4714354998051087 0.591263000709694 +20 ENSG0000010000 Tgd 9195 T A chr20:9195:T:A -149710 0.16837980736143288 0.6484857568007941 0.1380304500564553 0.8668255014327907 +20 ENSG0000010000 Tgd 276 G T chr20:276:G:T 264148 0.7081614965696739 0.16936958385900902 0.9145831141200009 0.8639614711833423 +20 ENSG0000010000 Tgd 8351 T G chr20:8351:T:G -494457 0.6814112031681472 0.8750727420547187 0.1533815085092336 0.7301214227414581 +20 ENSG0000010000 Tgd 3073 G T chr20:3073:G:T -437745 0.4297231153473817 0.6132579570031336 -0.22311772119295914 0.8252003507633012 +20 ENSG0000010000 Tgd 4796 C T chr20:4796:C:T -75830 0.973721493711845 0.41154301845093244 0.15666339230034865 0.2700908784403029 +20 ENSG0000010000 Tgd 2043 G C chr20:2043:G:C 179831 0.6052559204226526 0.0014526395336973419 -0.7707785605558015 0.5911466218007636 +20 ENSG0000010000 Tgd 4145 A T chr20:4145:A:T -361118 0.7110681909338101 0.2308556511859966 -0.5000080504286268 0.0475176477173062 +20 ENSG0000010000 Tgd 1183 G T chr20:1183:G:T -271269 0.2765490707710371 0.11261355559956077 -0.9943646691463441 0.21099475929527928 +20 ENSG0000010000 Tgd 1815 A G chr20:1815:A:G -387851 0.34135698680828097 0.4470745037822701 -0.7060248892856509 0.6483153801099351 +20 ENSG0000010000 Tgd 2020 C G chr20:2020:C:G 195331 0.20154894037363102 0.6350515719198844 -0.5864370705304887 0.353825011415874 +20 ENSG0000010000 Tgd 3978 C G chr20:3978:C:G -448690 0.25211126359594904 0.4332933907477744 -0.6827898016362699 0.7816116944853049 +20 ENSG0000010000 Tgd 977 G C chr20:977:G:C -286259 0.41340434633505696 0.8813065907896305 -0.7186042773210084 0.2800487512713895 +20 ENSG0000010000 Tgd 6983 A G chr20:6983:A:G 323861 0.7626333350657847 0.06529503007594084 -0.09114188927646016 0.30389249425832743 +20 ENSG0000010000 Tgd 3676 G T chr20:3676:G:T 221872 0.8638478091032472 0.8394679686191321 0.9270163534670308 0.270369853737189 +20 ENSG0000010000 Tgd 7871 T G chr20:7871:T:G 448758 0.13348673296828395 0.7810078131736886 0.2904407156393314 0.3851970677946061 +20 ENSG0000010000 Tgd 9040 T A chr20:9040:T:A -219322 0.7212426690074359 0.5220282320291636 0.37981569914273305 0.27254029800102414 +20 ENSG0000010000 Tgd 8463 C G chr20:8463:C:G -478715 0.06296777402725706 0.9571541315675424 -0.7857616954859232 0.8988768933901974 +20 ENSG0000010000 Tgd 4131 G A chr20:4131:G:A -343662 0.9586215169695768 0.32737667686114547 0.37927555694709003 0.5543185148709001 +20 ENSG0000010000 Tgd 9306 C A chr20:9306:C:A 4385 0.1934191375029971 0.10846623579128778 -0.3873238903152829 0.7643980535598385 +20 ENSG0000010000 Tgd 4116 C T chr20:4116:C:T 159393 0.40195367239293656 0.8419100266743748 0.20314466305398438 0.5644579852560954 +20 ENSG0000010000 Tgd 1575 C A chr20:1575:C:A 399464 0.33614797411025055 0.4713838305989394 -0.5176657358931605 0.33409575457615703 +20 ENSG0000010000 Tgd 3729 G A chr20:3729:G:A 223233 0.07626827138060632 0.5651589624280132 -0.726008530984753 0.41132456537846473 +20 ENSG0000010000 Tgd 719 T G chr20:719:T:G -67610 0.5349807142910067 0.7386153643772301 -0.7947696792936214 0.989784817449386 +20 ENSG0000010000 Tgd 8988 G T chr20:8988:G:T -268546 0.7380244747887085 0.21847045697925227 -0.8062876308468601 0.25720008258287697 +20 ENSG0000010000 Tgd 9626 G A chr20:9626:G:A -205968 0.6430192261086868 0.8898015651839739 0.7862054736775821 0.09438947587067979 +20 ENSG0000010000 Tgd 3879 C T chr20:3879:C:T -453684 0.47601246602085745 0.2770815010448928 -0.6659245393082944 0.757569073104657 +20 ENSG0000010000 Tgd 105 G T chr20:105:G:T 334375 0.41180899655422765 0.33074411079357224 -0.8225796296641164 0.5832963305272153 +20 ENSG0000010000 Tgd 9432 C A chr20:9432:C:A -52148 0.6963790830147177 0.9346548270948206 0.5066547759228319 0.5567305748555292 +20 ENSG0000010000 Tgd 2692 A C chr20:2692:A:C -298103 0.17206822948391753 0.1569541635678675 0.4749500013173247 0.7327077868894649 +20 ENSG0000010000 Tgd 3209 T C chr20:3209:T:C -16759 0.06127515928194871 0.44946701247710863 0.23729242584876764 0.0324594096001859 +20 ENSG0000010000 Tgd 3346 G T chr20:3346:G:T 221333 0.06326798225655894 0.901156493716455 -0.052539894311336655 0.008615171799091737 +20 ENSG0000010000 Tgd 6137 A T chr20:6137:A:T 217686 0.8429077110655634 0.42035665443930337 -0.8303453808364636 0.15837679088542894 +20 ENSG0000010000 Tgd 1200 T G chr20:1200:T:G -386293 0.434618459859916 0.6996875391349162 -0.6676216383853542 0.7139833156521737 +20 ENSG0000010000 Tgd 9094 C G chr20:9094:C:G -334958 0.8287755399735097 0.5942695925596936 0.3210332478179576 0.21637199823308345 +20 ENSG0000010000 Tgd 7358 G T chr20:7358:G:T 140626 0.8366900294625501 0.44507578968387385 -0.3685395976866981 0.6066750306035052 +20 ENSG0000010000 Tgd 329 T G chr20:329:T:G -190110 0.3755261285048579 0.5354477350776522 0.8544951392862907 0.8748500178890013 +20 ENSG0000010000 Tgd 1890 T A chr20:1890:T:A -259103 0.7370035775025902 0.5335428934511737 0.7143515961343778 0.5605047835099872 +20 ENSG0000010000 Tgd 6466 T A chr20:6466:T:A 43114 0.17979259445537155 0.8757990839466484 0.59788578937094 0.24124242787132605 +20 ENSG0000010000 Tgd 832 A T chr20:832:A:T 65185 0.5522773048547497 0.3391119578858902 0.0751329376330454 0.260398561156385 +20 ENSG0000010000 Tgd 5441 A G chr20:5441:A:G 14335 0.8502450126253175 0.2053003694095643 0.6057401119176764 0.221287312865829 +20 ENSG0000010000 Tgd 1465 T G chr20:1465:T:G -425095 0.42212240935057277 0.6338544752204885 -0.839686233732982 0.7603794547954243 +20 ENSG0000010000 Tgd 7552 T C chr20:7552:T:C 388380 0.33768148742586457 0.033106124143894355 -0.9769407692544527 0.028294484559662183 +20 ENSG0000010000 Tgd 397 C T chr20:397:C:T 294357 0.7421980411408255 0.6370391963857452 -0.8378736066425949 0.688268445232746 +20 ENSG0000010000 Tgd 7878 A G chr20:7878:A:G 321716 0.8942943032013724 0.6475477171803973 -0.885504844971511 0.6312151831069832 +20 ENSG0000010000 Tgd 9911 A T chr20:9911:A:T -129500 0.3128440259325881 0.672178559863251 0.5893791305163354 0.5045160721388565 +20 ENSG0000010000 Tgd 4750 T A chr20:4750:T:A 72286 0.812765875070867 0.6003482913087573 0.15277002066393708 0.47730155967098925 +20 ENSG0000010000 Tgd 8047 A T chr20:8047:A:T -315740 0.8243570235612143 0.2889771945880012 0.24330992681249763 0.04341737314909338 +20 ENSG0000010000 Tgd 6217 G A chr20:6217:G:A 31778 0.43468992015207386 0.026251353652375964 0.1984232969411186 0.0037927938429643754 +20 ENSG0000010000 Tgd 4281 T G chr20:4281:T:G -137873 0.6366679172328795 0.0886885550727452 0.44779845350817893 0.2758042345755188 +20 ENSG0000010000 Tgd 2457 A T chr20:2457:A:T -66968 0.14927305875495167 0.26940928035738 -0.5443104953964422 0.3223187793135399 +20 ENSG0000010000 Tgd 803 T G chr20:803:T:G 265040 0.04187315369057143 0.7142881083441972 0.2500338177348558 0.053983685868420984 +20 ENSG0000010000 Tgd 3407 T G chr20:3407:T:G 131350 0.8560256184206069 0.5582623739542338 0.23618220321948913 0.7867366996909847 +20 ENSG0000010000 Tgd 279 C A chr20:279:C:A 473223 0.12241046030261604 0.391676561927908 0.6697964300003021 0.12514019105817956 +20 ENSG0000010000 Tgd 9107 A C chr20:9107:A:C 155966 0.7332849968870104 0.9621520478795897 0.28755484785802765 0.5479301919601617 +20 ENSG0000010000 Tgd 7761 G T chr20:7761:G:T 40712 0.1938562048829191 0.7181813997317316 -0.624631993050556 0.6480948199115825 +20 ENSG0000010000 Tgd 6549 C T chr20:6549:C:T -337617 0.6729997922892165 0.14150095505002536 -0.1998347100753386 0.6782251403991576 +20 ENSG0000010000 Tgd 2800 C G chr20:2800:C:G -187958 0.15859286502532188 0.24271622210328359 -0.1604005730676734 0.7172741289390614 +20 ENSG0000010000 Tgd 6034 G T chr20:6034:G:T -390851 0.3095850345550004 0.7782948408413672 -0.8356634458606649 0.8735707482229029 +20 ENSG0000010000 Tgd 6393 C G chr20:6393:C:G -335718 0.3546760823290177 0.7502929670636724 0.5153160138519388 0.866407180924665 +20 ENSG0000010000 Tgd 694 T G chr20:694:T:G 326968 0.2290790581786939 0.6757509065348477 -0.3201385655482232 0.6835002123696234 +20 ENSG0000010000 Tgd 4815 T A chr20:4815:T:A 201145 0.08460685960823333 0.3772711329738011 -0.17761674833158003 0.2805078560800932 +20 ENSG0000010000 Tgd 4762 A T chr20:4762:A:T 266278 0.10896518355884988 0.2414433923072391 0.3948123380686317 0.5192281594520521 +20 ENSG0000010000 Tgd 4513 C T chr20:4513:C:T -11697 0.6100952389221889 0.6971905757600819 0.3473555697241022 0.34058907826619916 +20 ENSG0000010000 Tgd 4747 A C chr20:4747:A:C -249583 0.20463987377647985 0.21613346940977252 0.9394637907303336 0.8241136301659673 +20 ENSG0000010000 Tgd 3184 A G chr20:3184:A:G 263836 0.22187882517803448 0.14141607885023944 -0.7956486777952667 0.09548031399096715 +20 ENSG0000010000 Tgd 9829 A T chr20:9829:A:T 16508 0.2167822579645139 0.4049945074619966 -0.35395966471070683 0.22649188684800214 +20 ENSG0000010000 Tgd 6663 A G chr20:6663:A:G 295238 0.9617009783345539 0.9914219557444801 -0.8093844136340451 0.9607791967480095 +20 ENSG0000010000 Tgd 6672 A C chr20:6672:A:C 316455 0.4150226869584219 0.5497404346459136 0.6751935123979547 0.5243458751246494 +20 ENSG0000010000 Tgd 215 T G chr20:215:T:G -149931 0.4722730117800342 0.7028386033874128 -0.4722256998827883 0.28436553330881803 +20 ENSG0000010000 Tgd 9767 A G chr20:9767:A:G 461200 0.0030741086772178017 0.6210581040391382 -0.5725964696442871 0.36853694159636546 +20 ENSG0000010000 Tgd 5666 T A chr20:5666:T:A -420045 0.31122785511382967 0.07091268754388103 -0.7536527086668969 0.526435457323858 +20 ENSG0000010000 Tgd 9422 C A chr20:9422:C:A 65422 0.2922434898156232 0.23134950844200053 0.059777043422265086 0.34360734043439595 +20 ENSG0000010000 Tgd 433 T G chr20:433:T:G -295837 0.17060068856884847 0.7229540508812524 0.8832002761302231 0.6069617651877002 +20 ENSG0000010000 Tgd 8288 T A chr20:8288:T:A -248193 0.451291935704795 0.3351912672645947 -0.16346204166494882 0.0931325166515423 +20 ENSG0000010000 Tgd 598 C T chr20:598:C:T 44924 0.5361050323191875 0.9406677242155769 -0.9142931278112074 0.367469127989169 +20 ENSG0000010000 Tgd 349 C T chr20:349:C:T 16293 0.9355923339389007 0.4286695229662302 0.9325757740547047 0.7440133868181112 +20 ENSG0000010000 Tgd 295 A T chr20:295:A:T 417324 0.9902582619740624 0.5202565631638268 -0.5936355835002349 0.3911991496267354 +20 ENSG0000010000 Tgd 9953 G T chr20:9953:G:T 218178 0.4556287532499388 0.32037821367613395 0.4903225930460311 0.10084580026443227 +20 ENSG0000010000 Tgd 2876 T C chr20:2876:T:C 441090 0.3405334007426749 0.05205207182018212 -0.14041311280316404 0.5507410992027856 +20 ENSG0000010000 Tgd 7148 A G chr20:7148:A:G 156805 0.8474317154680948 0.42447355958113053 0.122741723718508 0.9025154441256313 +20 ENSG0000010000 Tgd 3455 T C chr20:3455:T:C 439902 0.5545307174694464 0.7938113698945185 0.9702937967692316 0.780463020830416 +20 ENSG0000010000 Tgd 5614 C T chr20:5614:C:T 52 0.8628336836927144 0.9127242755166307 0.4733162357468139 0.5290793501239923 +20 ENSG0000010000 Tgd 6676 A T chr20:6676:A:T -254899 0.6451355768315687 0.614508544831405 -0.751725747385616 0.10337226441769838 +20 ENSG0000010000 Tgd 6072 G A chr20:6072:G:A 135103 0.8222568634710554 0.5073994723576517 0.9863810027310516 0.5812627816486334 +20 ENSG0000010000 Tgd 1063 T A chr20:1063:T:A 249367 0.9953635219716126 0.9918940980378091 0.16579821418709817 0.16643543940374403 +20 ENSG0000010000 Tgd 9796 C G chr20:9796:C:G -405991 0.8891513833568425 0.29554751623556796 0.07052920436159904 0.36681431080177646 +20 ENSG0000010000 Tgd 6294 C A chr20:6294:C:A -191292 0.02127336541041358 0.5004383838723481 -0.3808134113329422 0.6191648378111887 +20 ENSG0000010000 Tgd 3186 A T chr20:3186:A:T 379950 0.7803349704077647 0.8193656446265273 -0.41113669007229636 0.14215092795709144 +20 ENSG0000010000 Tgd 7044 G A chr20:7044:G:A -72371 0.6222178690111457 0.02296067021804038 0.11581709195640011 0.155845815454392 +20 ENSG0000010000 Tgd 1929 A G chr20:1929:A:G -317638 0.7492765576832506 0.3095017564420376 0.8860630243225673 0.7246768732583689 +20 ENSG0000010000 Tgd 8520 T C chr20:8520:T:C 202699 0.6625433236539371 0.9078600135579833 0.30037917560282024 0.8986233779051548 +20 ENSG0000010000 Tgd 8524 T A chr20:8524:T:A 376579 0.8187729863892247 0.28470142802606224 -0.9938555226139607 0.3453382040117719 +20 ENSG0000010000 Tgd 6677 A T chr20:6677:A:T 446076 0.6951430482139277 0.6100070136349515 -0.3173205401012318 0.5497029434947719 +20 ENSG0000010000 Tgd 2413 G C chr20:2413:G:C 70950 0.6765541892246325 0.4341455747255579 -0.46792290965471595 0.7838172476966927 +20 ENSG0000010000 Tgd 6266 G C chr20:6266:G:C -73309 0.6303528329193901 0.9234614210517309 -0.5667357889572815 0.5622322670180137 +20 ENSG0000010000 Tgd 6979 A T chr20:6979:A:T 303724 0.19028661256456714 0.5285046347505947 0.14301403368789667 0.9804936397366386 +20 ENSG0000010000 Tgd 1970 C T chr20:1970:C:T 314972 0.2670470580359584 0.5414680849682691 -0.5187984021363974 0.7964872802076615 +20 ENSG0000010000 Tgd 5092 C A chr20:5092:C:A 396151 0.029454103354587757 0.9592225414830853 -0.04316534471015876 0.2245109496114939 +20 ENSG0000010000 Tgd 107 G A chr20:107:G:A -442171 0.11678394551359317 0.9796505478266921 -0.225625134946416 0.2028566147907203 +20 ENSG0000010000 Tgd 1331 T C chr20:1331:T:C 363565 0.9694925607988594 0.8544497640839616 -0.9041676976480557 0.06715620963883581 +20 ENSG0000010000 Tgd 8648 A C chr20:8648:A:C -416005 0.2930345805724115 0.6065336843815654 0.7156736364622465 0.3220713896547943 +20 ENSG0000010000 Tgd 7425 G T chr20:7425:G:T 404814 0.6295372361079433 0.1958995153892088 0.16492487414812596 0.44387030469947414 +20 ENSG0000010000 Tgd 6737 T A chr20:6737:T:A 265435 0.3683610574939159 0.6375028809890168 -0.4597569850561336 0.8958227554319317 +20 ENSG0000010000 Tgd 7220 G C chr20:7220:G:C -90282 0.1623122845454662 0.7143153693000296 -0.10194982759005566 0.14059077310037002 +20 ENSG0000010000 Tgd 9770 T C chr20:9770:T:C -479593 0.555464489748083 0.09206951965289567 0.7448966874494269 0.7252631790098868 +20 ENSG0000010000 Tgd 7769 G A chr20:7769:G:A -331209 0.5654213704115175 0.9324851676955684 -0.8664117787910532 0.7779621371051842 +20 ENSG0000010000 Tgd 373 G C chr20:373:G:C -429580 0.9702969729547838 0.19843924941619062 -0.09226712238620083 0.09009765989560221 +20 ENSG0000010000 Tgd 2174 C G chr20:2174:C:G -386006 0.4671927880099819 0.9271668052610071 -0.07148992999432413 0.20571212528419444 +20 ENSG0000010000 Tgd 2692 T A chr20:2692:T:A -101720 0.11262002750390065 0.7503376783572104 -0.5240540381496048 0.5137811340061178 +20 ENSG0000010000 Tgd 5207 T G chr20:5207:T:G 19829 0.5461127875256213 0.9764331083369644 -0.2480377834846943 0.19119681126650767 +20 ENSG0000010000 Tgd 7332 A C chr20:7332:A:C -177985 0.26459867203649146 0.04918420855691008 0.9224756683214541 0.8646934203746 +20 ENSG0000010000 Tgd 5293 A T chr20:5293:A:T 406098 0.39558854173136127 0.5102686214670632 0.9461571397999124 0.09542172702944707 +20 ENSG0000010000 Tgd 4513 C A chr20:4513:C:A -252004 0.45173864219255977 0.6820487398663605 0.6640008405091677 0.3989612183043929 +20 ENSG0000010000 Tgd 8753 A T chr20:8753:A:T 449006 0.46320508227435087 0.7909368239317708 0.3345527129380521 0.17114787490856162 +20 ENSG0000010000 Tgd 3059 T A chr20:3059:T:A 420840 0.4915753297080563 0.8206348686590275 0.07248799245540472 0.18320961735573127 +20 ENSG0000010000 Tgd 3169 C G chr20:3169:C:G -320044 0.5725197907248517 0.34013755421748726 0.6594948096767939 0.7846101507954097 +20 ENSG0000010000 Tgd 9937 G T chr20:9937:G:T 294693 0.4260205020500982 0.826333725688076 0.7494665059826391 0.539820539286631 +20 ENSG0000010000 Tgd 1884 T C chr20:1884:T:C -71736 0.0291569556181972 0.2289082897635203 0.5005424536711462 0.959807616986682 +20 ENSG0000010000 Tgd 376 G A chr20:376:G:A -24394 0.4783212520190443 0.06108894499137496 0.7218080749838707 0.496967938838258 +20 ENSG0000010000 Tgd 6637 T A chr20:6637:T:A -117180 0.7645360306073089 0.37611683115825534 -0.7127410458869861 0.6592516309979556 +20 ENSG0000010000 Tgd 2801 T A chr20:2801:T:A -87536 0.6787471240270935 0.659555147335235 -0.9703356954859708 0.33571596801679904 +20 ENSG0000010000 Tgd 7329 A C chr20:7329:A:C -75396 0.5694317977900841 0.732489646023975 0.04567491488608244 0.7703201167816671 +20 ENSG0000010000 Tgd 2855 A T chr20:2855:A:T -156705 0.5678670361483874 0.9689165387803742 0.5099260299529307 0.9549363213657988 +20 ENSG0000010000 Tgd 9135 C T chr20:9135:C:T -49154 0.6234369993877504 0.5418576396167583 0.5666986636329607 0.8682095731358983 +20 ENSG0000010000 Tgd 2595 T A chr20:2595:T:A 392204 0.3308816388129078 0.03391103410273777 0.2103330596058557 0.7299071532902812 +20 ENSG0000010000 Tgd 8885 G C chr20:8885:G:C 32006 0.9690656162192494 0.6483706543593717 -0.40372546192271774 0.6059920350267233 +20 ENSG0000010000 Tgd 9990 A G chr20:9990:A:G -403882 0.356937869814406 0.17904229637444702 0.7903921089167729 0.4022516770521669 +20 ENSG0000010000 Tgd 6398 G T chr20:6398:G:T 65465 0.7691073043056545 0.6567267342415529 -0.9475642154529043 0.6159672889527262 +20 ENSG0000010000 Tgd 4504 G A chr20:4504:G:A 143851 0.06348109036243499 0.6278189842678025 0.9467147657484705 0.49540335848049444 +20 ENSG0000010000 Tgd 8720 T G chr20:8720:T:G 30375 0.49722607969149746 0.8455112811469683 0.6740900104357017 0.13035802936402074 +20 ENSG0000010000 Tgd 8457 T G chr20:8457:T:G 286185 0.03817992501354217 0.6433056558083047 -0.3634922849899125 0.5248623768139926 +20 ENSG0000010000 Tgd 6531 C A chr20:6531:C:A 229286 0.26932721497878775 0.02989775436796327 0.7894334624378012 0.3609969105557469 +20 ENSG0000010000 Tgd 7482 A T chr20:7482:A:T -206822 0.8997667546702183 0.17590720786436698 0.49294558678018263 0.8526291173633543 +20 ENSG0000010000 Tgd 4397 C T chr20:4397:C:T 479612 0.5235848754135769 0.460685816359482 -0.21186598843176307 0.14121380496521968 +20 ENSG0000010000 Tgd 4820 T C chr20:4820:T:C 327887 0.39138536028793725 0.8663728700741913 0.7325842669696394 0.19537324327704236 +20 ENSG0000010000 Tgd 9382 A C chr20:9382:A:C -75431 0.16442153052038255 0.07960694793216327 0.36105897897477623 0.32855278638314594 +20 ENSG0000010000 Tgd 8734 C G chr20:8734:C:G -313460 0.9139538477735548 0.3433506741305927 -0.6646413360740544 0.5758682352057496 +20 ENSG0000010000 Tgd 6614 A T chr20:6614:A:T 402247 0.9914292763142245 0.5044812418983178 0.11986703739487048 0.3918280939002498 +20 ENSG0000010000 Tgd 5994 A G chr20:5994:A:G 44142 0.2628493529279453 0.38627909086329537 0.7002445095581546 0.3250519758955894 +20 ENSG0000010000 Tgd 9993 C G chr20:9993:C:G 310552 0.6801030657239612 0.824861990375124 -0.5515865831434381 0.194965380298441 +20 ENSG0000010000 Tgd 1966 T A chr20:1966:T:A -291179 0.5215425925927201 0.7046861151875192 0.16395391875532273 0.26986464855565157 +20 ENSG0000010000 Tgd 618 A C chr20:618:A:C -279605 0.3945307531027531 0.08820725474689883 -0.41270002046709164 0.10841510900438614 +20 ENSG0000010000 Tgd 5371 T A chr20:5371:T:A -272883 0.7289324713759844 0.36611012085809946 0.7721977712879715 0.8177212770660536 +20 ENSG0000010000 Tgd 7797 A T chr20:7797:A:T 337606 0.4262500811169062 0.8515593284168856 -0.9084156600228437 0.9598404105391355 +20 ENSG0000010000 Tgd 4355 T A chr20:4355:T:A -202751 0.9503867907059146 0.7924542657072621 -0.9296156201312884 0.35450564836075465 +20 ENSG0000010000 Tgd 7482 G A chr20:7482:G:A 229891 0.5917348006644919 0.47288771392021767 -0.8797153442342318 0.7327692794656547 +20 ENSG0000010000 Tgd 2157 G A chr20:2157:G:A -215121 0.3609865913523427 0.23500993732141096 0.02851154695128022 0.558247009587265 +20 ENSG0000010000 Tgd 5707 G T chr20:5707:G:T 433426 0.13684976797680537 0.3308932226703061 0.6181957708730228 0.809582351022089 +20 ENSG0000010000 Tgd 7015 G A chr20:7015:G:A -159785 0.8640344200501259 0.5835671239080983 -0.16897465598142758 0.7545357055092594 +20 ENSG0000010000 Tgd 8830 G C chr20:8830:G:C -186843 0.8625926834910352 0.13821906218463076 0.41220330205396594 0.5106981550004187 +20 ENSG0000010000 Tgd 4582 C G chr20:4582:C:G -118623 0.7966024493187195 0.31732728174036573 0.4253523028131774 0.6140341728906675 +20 ENSG0000010000 Tgd 2913 T C chr20:2913:T:C 144226 0.9104867511887682 0.9676343953831334 0.6248357697305118 0.42867916917354393 +20 ENSG0000010000 Tgd 5445 A T chr20:5445:A:T 477875 0.8510131389368888 0.8824899944618507 -0.9142501330980193 0.8018198700214507 +20 ENSG0000010000 Tgd 6104 A T chr20:6104:A:T -362503 0.6426504990262667 0.8258174425593321 0.9824002657395037 0.11661781395608774 +20 ENSG0000010000 Tgd 5341 C A chr20:5341:C:A -281536 0.005569706290785903 0.33992977053321294 -0.9324213933678434 0.2048871792464288 +20 ENSG0000010000 Tgd 6975 T A chr20:6975:T:A -202300 0.3032624295678955 0.8511221224055365 0.04958378697795518 0.3836844910415993 +20 ENSG0000010000 Tgd 9609 G T chr20:9609:G:T 23852 0.9630952764327976 0.6903606577997136 0.873306247921072 0.42364926166501155 +20 ENSG0000010000 Tgd 7227 C G chr20:7227:C:G -343024 0.7469001114842696 0.1297365603319861 0.691926501919538 0.98480518306799 +20 ENSG0000010000 Tgd 2748 T A chr20:2748:T:A 51370 0.21843863878685799 0.8135672448044561 0.41513159190661764 0.8079214243034993 +20 ENSG0000010000 Tgd 1735 A T chr20:1735:A:T -290095 0.6065792377532467 0.8786640229908156 0.2902957798106116 0.6272850508508427 +20 ENSG0000010000 Tgd 1518 A G chr20:1518:A:G 274159 0.008114851157979164 0.08985098093443056 -0.5105030325745346 0.26312798096275564 +20 ENSG0000010000 Tgd 2624 T G chr20:2624:T:G -138234 0.02422538796449536 0.16505914007823919 -0.05667851263246915 0.5191626191769579 +20 ENSG0000010000 Tgd 1427 G T chr20:1427:G:T 325148 0.18066520169266786 0.3500877058511941 -0.07147714017556828 0.2610803257083875 +20 ENSG0000010000 Tgd 5951 C G chr20:5951:C:G -357744 0.37890960391428263 0.8627377344013661 0.8842754517897036 0.32610880454110586 +20 ENSG0000010000 Tgd 1479 T A chr20:1479:T:A -88439 0.05309646240900512 0.8690303577605821 0.4365781760146694 0.9603902308330597 +20 ENSG0000010000 Tgd 7681 T A chr20:7681:T:A -20626 0.6874828429152706 0.1983211893059187 0.5744233089267365 0.7285751529786932 +20 ENSG0000010000 Tgd 9249 T A chr20:9249:T:A -158351 0.18178925791787992 0.1551916493225698 0.9103856022190244 0.9097318896889268 +20 ENSG0000010000 Tgd 3508 G T chr20:3508:G:T -394294 0.7328051285974685 0.7994029620807968 0.31449420532386685 0.5855915599412285 +20 ENSG0000010000 Tgd 4968 C G chr20:4968:C:G -371910 0.48910322580327137 0.6446064894126909 0.47422986840695147 0.8826238380715897 +20 ENSG0000010000 Tgd 3586 T G chr20:3586:T:G -196078 0.2471353034816559 0.019560311518935225 -0.33475166170242554 0.8655677401098784 +20 ENSG0000010000 Tgd 9464 G A chr20:9464:G:A -310774 0.8932719040425622 0.6036074222987073 0.6958877423497174 0.5826835243057996 +20 ENSG0000010000 Tgd 45 G A chr20:45:G:A -330037 0.05543752261332957 0.24648935099482916 0.8021451919659344 0.46904250237335177 +20 ENSG0000010000 Tgd 8635 G A chr20:8635:G:A -275357 0.49032749763070527 0.895382723342629 -0.3462464639801479 0.5799989772013182 +20 ENSG0000010000 Tgd 1615 T C chr20:1615:T:C -83578 0.7292030885114203 0.7261093174142998 -0.8914187617901046 0.18925201781908463 +20 ENSG0000010000 Tgd 617 A C chr20:617:A:C 297962 0.5542100182842122 0.606579965433723 0.8794537735881587 0.8849405939589173 +20 ENSG0000010000 Tgd 8498 G C chr20:8498:G:C 216803 0.21058573345333043 0.7399811202439999 0.40990578947239054 0.3728206940865557 +20 ENSG0000010000 Tgd 8427 C T chr20:8427:C:T -251702 0.6374271328373966 0.39434576723204984 -0.8782379806236618 0.8380165974022811 +20 ENSG0000010000 Tgd 663 T A chr20:663:T:A -208360 0.9779898472287023 0.23628733994472517 -0.22429776720096406 0.08292787047369816 +20 ENSG0000010000 Tgd 9383 C A chr20:9383:C:A -17430 0.06640843560462784 0.8351840814339013 -0.6739905036375793 0.21084136498074682 +20 ENSG0000010000 Tgd 9348 C A chr20:9348:C:A -403033 0.3027906581672988 0.4779687395482076 0.307509405432 0.735187200172764 +20 ENSG0000010000 Tgd 3160 A T chr20:3160:A:T 455938 0.004912477556982431 0.41558440768851657 -0.05980677779543675 0.21120668730949424 +20 ENSG0000010000 Tgd 9724 G A chr20:9724:G:A 138265 0.9674146034953753 0.14518405048414695 -0.9031670744226772 0.15178078969585646 +20 ENSG0000010000 Tgd 2487 A T chr20:2487:A:T -334950 0.11807921429522994 0.6867859506904148 0.4008039975183306 0.4608844124578043 +20 ENSG0000010000 Tgd 7645 T A chr20:7645:T:A -379240 0.6058373136175937 0.7460210746037789 -0.8215268237004594 0.11359687511771524 +20 ENSG0000010000 Tgd 6598 A T chr20:6598:A:T 457649 0.1807069781560534 0.1209567905776795 0.4433413748728834 0.44704451304562964 +20 ENSG0000010000 Tgd 5619 G T chr20:5619:G:T -292433 0.9254829855484814 0.7467730919247935 -0.5718215549435761 0.2943186114304659 +20 ENSG0000010000 Tgd 3154 C T chr20:3154:C:T 62192 0.013409068139919711 0.17883769016968643 0.301253048730977 0.6654786575544472 +20 ENSG0000010000 Tgd 4940 A T chr20:4940:A:T 301489 0.7850010118040813 0.17613716498359044 -0.8197990762524243 0.02368672571366393 +20 ENSG0000010000 Tgd 9149 G T chr20:9149:G:T 466712 0.33715562417986866 0.008742157939296558 0.3298469681537042 0.9820018576271803 +20 ENSG0000010000 Tgd 2460 C G chr20:2460:C:G -364936 0.017114898860390304 0.8232381909445018 -0.6126922115590321 0.8470262193110619 +20 ENSG0000010000 Tgd 5734 G A chr20:5734:G:A 349833 0.7421120534537974 0.6551563888880317 0.6107243140146248 0.2154035484862153 +20 ENSG0000010000 Tgd 9321 C T chr20:9321:C:T 317070 0.6945605843026852 0.49655806141714487 -0.9658229235356601 0.09807089180226893 +20 ENSG0000010000 Tgd 7434 A T chr20:7434:A:T -211158 0.19075643587009694 0.9351688501165514 0.09938994536755885 0.5400996873551899 +20 ENSG0000010000 Tgd 6347 C T chr20:6347:C:T -277689 0.8463421093452137 0.25935726569229856 -0.850101979254152 0.742902758179177 +20 ENSG0000010000 Tgd 2559 A T chr20:2559:A:T 5258 0.9301852289871528 0.4224597895377341 -0.27635484018547607 0.16279190873973956 +20 ENSG0000010000 Tgd 3782 G C chr20:3782:G:C -436762 0.16635183691283162 0.6194247757011544 -0.11377084674178106 0.7218259515317531 +20 ENSG0000010000 Tgd 1399 A G chr20:1399:A:G -260714 0.1299876058584658 0.8600109016999511 0.062094400079462764 0.9452072860018825 +20 ENSG0000010000 Tgd 1754 C T chr20:1754:C:T 367977 0.8785871839854769 0.6317347335967495 -0.9848450538242326 0.7014998036073251 +20 ENSG0000010000 Tgd 4677 A T chr20:4677:A:T -438504 0.1246946827833364 0.6161372018097845 0.8159610167905131 0.40613446404511083 +20 ENSG0000010000 Tgd 8133 G C chr20:8133:G:C -56255 0.8930425330015984 0.3082593278803408 -0.8702352289723159 0.4433694560940025 +20 ENSG0000010000 Tgd 5703 G T chr20:5703:G:T 491711 0.2460975367671342 0.47957149775012387 -0.7871499488225706 0.8369334350696036 +20 ENSG0000010000 Tgd 4115 A T chr20:4115:A:T -472061 0.8060967468579701 0.7366830616632842 -0.1748545385324456 0.2306210827699066 +20 ENSG0000010000 Tgd 7362 G C chr20:7362:G:C 300529 0.9432096264509907 0.4889842060347971 -0.15238944416821143 0.043580818554969585 +20 ENSG0000010000 Tgd 216 A C chr20:216:A:C -30489 0.10740215441683032 0.5927473755961808 0.7368651884763331 0.10907343634387073 +20 ENSG0000010000 Tgd 5616 A G chr20:5616:A:G -411464 0.19548575213822028 0.04245062476833783 -0.09407374111314959 0.24725650033972557 +20 ENSG0000010000 Tgd 7569 T C chr20:7569:T:C -416421 0.9687753099784134 0.8129971539246229 -0.424549395425303 0.9699992998478072 +20 ENSG0000010000 Tgd 4515 G C chr20:4515:G:C -290815 0.8010266453073704 0.17498062636111567 0.4081294863902567 0.025765355441064952 +20 ENSG0000010000 Tgd 9260 G T chr20:9260:G:T -134117 0.5316916917220096 0.5281223258105376 -0.28933296431869526 0.4264824835561539 +20 ENSG0000010000 Tgd 7037 C G chr20:7037:C:G -468875 0.2045618975199488 0.5612578615953525 -0.33247458638303296 0.9997589741153993 +20 ENSG0000010000 Tgd 3283 G T chr20:3283:G:T 362543 0.8098660477955356 0.9387404355367737 0.8439385034772922 0.8384923809918566 +20 ENSG0000010000 Tgd 6450 G T chr20:6450:G:T -417233 0.35323373664280167 0.06407455000740225 -0.5189043308691228 0.13908379958404424 +20 ENSG0000010000 Tgd 7783 A C chr20:7783:A:C -77441 0.41480402220460433 0.10016717248112916 0.9301618982900939 0.6272108077460891 +20 ENSG0000010000 Tgd 409 A G chr20:409:A:G 117101 0.48565368105870876 0.4673586199009673 0.8278587945150826 0.03831338596812042 +20 ENSG0000010000 Tgd 4304 T A chr20:4304:T:A 360406 0.7149027627924143 0.75728723183225 0.715840633325389 0.6314435007329406 +20 ENSG0000010000 Tgd 4417 A C chr20:4417:A:C -238600 0.6677096858433261 0.7077289079560252 -0.366668182843064 0.1729484508801596 +20 ENSG0000010000 Tgd 4187 A C chr20:4187:A:C 177992 0.8301309540713826 0.8217116631336944 0.8585220562305438 0.3956052100698838 +20 ENSG0000010000 Tgd 9931 G T chr20:9931:G:T 179505 0.06511864959198066 0.4632477580779578 -0.12196530870861255 0.12115765445568887 diff --git a/example_data/dummy_out_ENSG0000010000.tsv.gz b/example_data/dummy_out_ENSG0000010000.tsv.gz index 79e5937..3df96c0 100644 Binary files a/example_data/dummy_out_ENSG0000010000.tsv.gz and b/example_data/dummy_out_ENSG0000010000.tsv.gz differ diff --git a/example_data/dummy_out_ENSG0000010001.tsv b/example_data/dummy_out_ENSG0000010001.tsv new file mode 100644 index 0000000..c68b861 --- /dev/null +++ b/example_data/dummy_out_ENSG0000010001.tsv @@ -0,0 +1,2001 @@ +Chr Gene cell.type pos a0 a1 SNP START EAF p beta se +20 ENSG0000010001 Tgd 106793 G C chr20:106793:G:C -392988 0.41088721087631397 0.38200402226635843 -0.8008464701706193 0.2170673021783714 +20 ENSG0000010001 Tgd 104697 A G chr20:104697:A:G 3203 0.5710179006023267 0.24824180627836934 0.6618329163520844 0.76243291016666 +20 ENSG0000010001 Tgd 107159 C A chr20:107159:C:A 140204 0.4460679799840853 0.014660478137400679 0.4229737791798407 0.9111597696978568 +20 ENSG0000010001 Tgd 102706 G T chr20:102706:G:T -472416 0.21434224745086183 0.050980795290851866 -0.0785164114860637 0.9041723845899833 +20 ENSG0000010001 Tgd 102811 G A chr20:102811:G:A 381881 0.1583584745284613 0.6653579820637692 -0.9451411868508961 0.8034462561069405 +20 ENSG0000010001 Tgd 104252 T C chr20:104252:T:C 217588 0.7018169965663974 0.6152094794181172 0.02591047578266159 0.5049523083274514 +20 ENSG0000010001 Tgd 109580 G T chr20:109580:G:T 441041 0.11195670130476942 0.9760113019083202 0.925038457250791 0.7312257752749621 +20 ENSG0000010001 Tgd 108807 C A chr20:108807:C:A 354923 0.8203485522523566 0.07060939051589521 0.09323632609957055 0.399602655517082 +20 ENSG0000010001 Tgd 104261 C T chr20:104261:C:T -331477 0.7578326696175551 0.45129134466352405 0.7603546661651335 0.3566948094399596 +20 ENSG0000010001 Tgd 108408 T G chr20:108408:T:G 31468 0.3737992825930404 0.9325069711471649 0.07819950837753753 0.06265276940210467 +20 ENSG0000010001 Tgd 100421 C A chr20:100421:C:A -60870 0.4743076363220672 0.47327525665301107 -0.8126058604000415 0.8427500280786315 +20 ENSG0000010001 Tgd 103096 G A chr20:103096:G:A -185894 0.5956803888323121 0.09150370780087669 0.2959039906856975 0.08494848764102549 +20 ENSG0000010001 Tgd 102586 G C chr20:102586:G:C 329909 0.16534943580554207 0.6704123424252458 0.11937782025056509 0.5051820201820625 +20 ENSG0000010001 Tgd 107592 A C chr20:107592:A:C -454770 0.5888416793543193 0.22933726544217758 -0.7641720286212648 0.9048167903175979 +20 ENSG0000010001 Tgd 101449 G A chr20:101449:G:A -128165 0.42714965376273684 0.49435547664453816 0.10369601312766674 0.2488634060386736 +20 ENSG0000010001 Tgd 107988 C T chr20:107988:C:T -150503 0.7228653086527201 0.3540425830111569 0.5580613751859986 0.46077925718913004 +20 ENSG0000010001 Tgd 106524 T C chr20:106524:T:C 171087 0.04516757938837601 0.6047468105422489 -0.1567349776325968 0.6400143511873255 +20 ENSG0000010001 Tgd 109992 T C chr20:109992:T:C 481002 0.6118039371766764 0.025621036184167 -0.09388046694247998 0.3130812802205809 +20 ENSG0000010001 Tgd 101062 G A chr20:101062:G:A -339622 0.5608331437261247 0.10220967520725133 -0.7153206145792121 0.9812450609988285 +20 ENSG0000010001 Tgd 105826 T G chr20:105826:T:G -211414 0.5426196571194521 0.1250576972987003 0.005065693969447116 0.5742964753075981 +20 ENSG0000010001 Tgd 103638 C G chr20:103638:C:G 58580 0.6966878287628947 0.22795206020832237 -0.9178241211126108 0.4364723283970499 +20 ENSG0000010001 Tgd 104236 T G chr20:104236:T:G 131182 0.575750247151776 0.4249144347165139 0.24647812296480853 0.06434656734833612 +20 ENSG0000010001 Tgd 104914 A T chr20:104914:A:T 369999 0.11294620176030645 0.8960597273460671 0.98844205923037 0.24903686952881038 +20 ENSG0000010001 Tgd 109826 G A chr20:109826:G:A -256050 0.2133437952034949 0.7197144508930481 0.7888849377695384 0.3423872874855532 +20 ENSG0000010001 Tgd 104074 A C chr20:104074:A:C -163179 0.5562937744784621 0.09439555854058479 -0.3350985679066354 0.8302287297221378 +20 ENSG0000010001 Tgd 100360 T C chr20:100360:T:C 450459 0.9561482614160824 0.7504764594293248 -0.008816076149872565 0.26292055309895246 +20 ENSG0000010001 Tgd 101596 G C chr20:101596:G:C 181874 0.03156579936326964 0.19324861241142854 -0.42169566044807305 0.029226706913935082 +20 ENSG0000010001 Tgd 109294 A G chr20:109294:A:G 292309 0.7403355649429528 0.8965757035579834 0.8627159855890543 0.06626824718436194 +20 ENSG0000010001 Tgd 108451 T C chr20:108451:T:C 123427 0.5382401464375449 0.7530081610874918 0.2609738415752485 0.5471576739065406 +20 ENSG0000010001 Tgd 100047 T A chr20:100047:T:A -215314 0.07961945565678896 0.2708700777120848 0.03394318890260006 0.9952811307793981 +20 ENSG0000010001 Tgd 103711 C T chr20:103711:C:T 463763 0.39451964666388994 0.37653176447141856 -0.4699470915509014 0.4227629201028622 +20 ENSG0000010001 Tgd 108822 T G chr20:108822:T:G 230311 0.6185450967367896 0.440346630749224 0.8606195823359963 0.3817812542740566 +20 ENSG0000010001 Tgd 105118 A C chr20:105118:A:C -143186 0.5883521904142116 0.9788961880919014 0.6071585813150793 0.05025122935723762 +20 ENSG0000010001 Tgd 102034 A G chr20:102034:A:G -121133 0.2463965020849621 0.9287483273557566 0.7783076419646542 0.045443944207651715 +20 ENSG0000010001 Tgd 101858 A G chr20:101858:A:G -417576 0.4224821603504274 0.7281976495822304 -0.5458615447204707 0.5964105324617002 +20 ENSG0000010001 Tgd 109098 G T chr20:109098:G:T -58289 0.314388008777446 0.4107895938743965 0.4187132514658345 0.12663727401873692 +20 ENSG0000010001 Tgd 108433 C A chr20:108433:C:A -102608 0.4855081290578718 0.04915172625164088 0.18823478603458388 0.6516760261567491 +20 ENSG0000010001 Tgd 104934 T C chr20:104934:T:C 56115 0.9712747527686051 0.25021775200163976 -0.9060833857459225 0.9205879386660395 +20 ENSG0000010001 Tgd 106145 C G chr20:106145:C:G -47708 0.49750344761058907 0.05000234638806045 0.5783558403820392 0.2628686673169393 +20 ENSG0000010001 Tgd 100236 G C chr20:100236:G:C 13832 0.7562662992112045 0.3399167398923483 0.7849272195873289 0.5716389391583998 +20 ENSG0000010001 Tgd 105055 C T chr20:105055:C:T -298372 0.7812594958128173 0.8052646265075409 -0.942217328769692 0.131724974500195 +20 ENSG0000010001 Tgd 106055 C G chr20:106055:C:G 418432 0.38126040088593294 0.13080613206541702 0.26706667519100535 0.7706542796888592 +20 ENSG0000010001 Tgd 105514 C A chr20:105514:C:A -386336 0.3964903848813772 0.3340020820770446 0.2164802901003282 0.22967321374585434 +20 ENSG0000010001 Tgd 100880 A G chr20:100880:A:G -331951 0.8555754884089384 0.11841428410193255 -0.6956883476061773 0.18186290847745304 +20 ENSG0000010001 Tgd 107405 G C chr20:107405:G:C -79274 0.13433655920482357 0.31600524196977264 -0.8653354586639477 0.02872114954555508 +20 ENSG0000010001 Tgd 101296 T C chr20:101296:T:C 243588 0.9834939323359333 0.09230015704415184 0.8214378501834303 0.8519350538913691 +20 ENSG0000010001 Tgd 104116 G A chr20:104116:G:A -493584 0.7604929425152931 0.979428854114193 -0.9699719830103539 0.4751107435838961 +20 ENSG0000010001 Tgd 108459 G T chr20:108459:G:T -294601 0.8746188065345 0.17288915498435176 0.1910487842929145 0.9418268058300506 +20 ENSG0000010001 Tgd 107276 A C chr20:107276:A:C -32215 0.1349100172088743 0.7182783216874947 0.5850566366780134 0.8528890522267358 +20 ENSG0000010001 Tgd 106964 A T chr20:106964:A:T 265929 0.11090772539020888 0.16462389419578916 -0.5922181080466229 0.2519772919683065 +20 ENSG0000010001 Tgd 107844 C T chr20:107844:C:T -49025 0.34571923089350975 0.5887422019950764 -0.2282611002564674 0.7528064213973108 +20 ENSG0000010001 Tgd 100788 G C chr20:100788:G:C 358784 0.635558010405329 0.3684957845762451 -0.4705457993151547 0.5145420466412127 +20 ENSG0000010001 Tgd 105076 T A chr20:105076:T:A 204380 0.5574920825266548 0.751178549472695 0.006925379101915263 0.8787713019621712 +20 ENSG0000010001 Tgd 105932 C A chr20:105932:C:A -467038 0.6758206333560701 0.42923725585985684 -0.3889938346621209 0.3680598047742377 +20 ENSG0000010001 Tgd 107655 C T chr20:107655:C:T 412125 0.1968093279414619 0.8800544744484409 -0.7771926799424933 0.9445198704626824 +20 ENSG0000010001 Tgd 102526 G C chr20:102526:G:C 307142 0.5372669072060035 0.7653499896562023 0.4619444307260292 0.4917622021398687 +20 ENSG0000010001 Tgd 101391 G T chr20:101391:G:T -245305 0.6644980482270555 0.6450649026149188 0.35703643772395677 0.16719128245708284 +20 ENSG0000010001 Tgd 102781 A T chr20:102781:A:T 409754 0.8326040324202838 0.5388959599994642 0.37016599133187444 0.8198280970953642 +20 ENSG0000010001 Tgd 107779 C A chr20:107779:C:A 186874 0.5429019858001038 0.8011961195379114 -0.8654568999001306 0.7842541284385163 +20 ENSG0000010001 Tgd 104046 A C chr20:104046:A:C -155070 0.7147581848155085 0.19436191792190172 -0.22677399800895492 0.994335627652953 +20 ENSG0000010001 Tgd 103761 C T chr20:103761:C:T -220277 0.6241289592816995 0.22943725683558036 0.6955409233200309 0.8812154773866989 +20 ENSG0000010001 Tgd 100194 A G chr20:100194:A:G -38059 0.47417063642409796 0.28660573448381255 0.8100059638464578 0.8427176076289986 +20 ENSG0000010001 Tgd 105659 T C chr20:105659:T:C -233555 0.2543933012842369 0.670025936927732 -0.2810710778586156 0.26262568087182925 +20 ENSG0000010001 Tgd 100877 T C chr20:100877:T:C 221875 0.06595738586121369 0.6027674050594947 -0.5651146106371814 0.7048722268230762 +20 ENSG0000010001 Tgd 109052 C T chr20:109052:C:T 174915 0.5957564199219111 0.14708356214039675 -0.08701334952794038 0.5028368861301231 +20 ENSG0000010001 Tgd 104186 T A chr20:104186:T:A -179058 0.9932076706385896 0.31450207890004556 0.15755034540709212 0.13371205646301007 +20 ENSG0000010001 Tgd 107854 A C chr20:107854:A:C 380537 0.44941413909959593 0.13753029148126472 -0.24631566952837725 0.037392758543890674 +20 ENSG0000010001 Tgd 101468 G C chr20:101468:G:C -316469 0.2677996168449608 0.9045585632602504 0.6632831030599333 0.6490487847637963 +20 ENSG0000010001 Tgd 109706 G T chr20:109706:G:T 46794 0.23546582637926305 0.5680131747748611 -0.7935933150209804 0.9758101260111993 +20 ENSG0000010001 Tgd 109007 G A chr20:109007:G:A -89067 0.9199506179758264 0.15711636054293399 0.7631270522859877 0.21088016684667782 +20 ENSG0000010001 Tgd 102825 A T chr20:102825:A:T -324067 0.14570567847137583 0.04478210073869171 -0.766054048912185 0.18592915937892657 +20 ENSG0000010001 Tgd 102880 A G chr20:102880:A:G -16283 0.4339705212369741 0.11461433056972625 0.8200815026432346 0.5084152614581121 +20 ENSG0000010001 Tgd 109780 A C chr20:109780:A:C -301452 0.37267134624507936 0.7968595854412054 -0.4224722227199105 0.9173519065065788 +20 ENSG0000010001 Tgd 103855 T A chr20:103855:T:A 118274 0.5103347506755378 0.04736468036598551 -0.034824307615107575 0.42171902235787606 +20 ENSG0000010001 Tgd 109017 G C chr20:109017:G:C 372475 0.6762812121965399 0.09765814270726747 -0.9927001714921633 0.7336019121879457 +20 ENSG0000010001 Tgd 100277 T A chr20:100277:T:A -111966 0.817369735357019 0.2789477031190575 -0.3411520428583492 0.7424522985349444 +20 ENSG0000010001 Tgd 106213 G A chr20:106213:G:A -152495 0.01954515951081648 0.6890316087460309 -0.12817668269796934 0.97247166474156 +20 ENSG0000010001 Tgd 106389 G C chr20:106389:G:C -403503 0.07382574687184318 0.9049870941587153 -0.21402524536639644 0.37159748735868714 +20 ENSG0000010001 Tgd 101418 A T chr20:101418:A:T -204100 0.001585646031520116 0.44702094451825203 -0.3521379813466732 0.3994244574569491 +20 ENSG0000010001 Tgd 109691 C G chr20:109691:C:G -456005 0.5227927462397183 0.01504439389172374 0.5460111582532201 0.7604485781971565 +20 ENSG0000010001 Tgd 107044 G T chr20:107044:G:T -191508 0.5539610917927824 0.37792064647596946 0.45123120497864555 0.5650371148452777 +20 ENSG0000010001 Tgd 106640 T G chr20:106640:T:G 136415 0.45911333549701894 0.015426632225174264 -0.531840316356188 0.4340155850460531 +20 ENSG0000010001 Tgd 109101 A G chr20:109101:A:G 54842 0.9950065067569032 0.6604118394914174 -0.029409858858745253 0.6147508628336728 +20 ENSG0000010001 Tgd 105966 A C chr20:105966:A:C 341850 0.5913619058486396 0.18061008574829507 -0.09293140703599234 0.07845683254882947 +20 ENSG0000010001 Tgd 107447 G A chr20:107447:G:A 226886 0.5947015973683264 0.12650419788268907 0.8865360332574765 0.133568348930637 +20 ENSG0000010001 Tgd 105874 G T chr20:105874:G:T -101394 0.014692539742035104 0.9777778616447694 0.10659204207033768 0.006838515939499157 +20 ENSG0000010001 Tgd 109366 C T chr20:109366:C:T 486442 0.07283966082308502 0.46098551423256773 -0.32877119614933803 0.3150402288253896 +20 ENSG0000010001 Tgd 101930 G C chr20:101930:G:C 240364 0.09021233522120264 0.7479532147792707 -0.023444499123128404 0.38571147280574625 +20 ENSG0000010001 Tgd 103030 T C chr20:103030:T:C -403634 0.6085516714511073 0.5922206223220596 0.8799307664896663 0.4363067122698192 +20 ENSG0000010001 Tgd 102901 G C chr20:102901:G:C 37108 0.5876348769251117 0.4492791001006555 0.6223255203237077 0.8817598060645728 +20 ENSG0000010001 Tgd 104331 T A chr20:104331:T:A 363300 0.5535521086052912 0.6810152552548682 -0.2543031798883295 0.8336055373934903 +20 ENSG0000010001 Tgd 100744 C G chr20:100744:C:G 317367 0.5057976106287467 0.0028861451515691527 0.15595571907663253 0.12720220568567153 +20 ENSG0000010001 Tgd 106016 G A chr20:106016:G:A 244810 0.5745226146136359 0.9380969385379354 -0.9004379203413528 0.6324861470602388 +20 ENSG0000010001 Tgd 103598 C G chr20:103598:C:G -211528 0.9506391439798558 0.4593581570064803 -0.5774557616221785 0.1368764171538329 +20 ENSG0000010001 Tgd 107701 A G chr20:107701:A:G 45438 0.6519496511319269 0.9124140129747024 0.0334203121478589 0.1617568463098888 +20 ENSG0000010001 Tgd 104290 G T chr20:104290:G:T -405535 0.13624972100321797 0.4196852972543834 -0.2210278519750013 0.9340264292709729 +20 ENSG0000010001 Tgd 106114 A G chr20:106114:A:G -430888 0.05891745378301427 0.35143227087684825 0.12491653325379515 0.6983169354521114 +20 ENSG0000010001 Tgd 100967 C A chr20:100967:C:A 140070 0.17800025525570284 0.46382185731760095 0.6145246343196524 0.9810738234778145 +20 ENSG0000010001 Tgd 101412 C T chr20:101412:C:T -51835 0.08087082764157294 0.8801119405300885 0.48773634974252156 0.22818535454613906 +20 ENSG0000010001 Tgd 107219 A T chr20:107219:A:T -290695 0.0438501464786234 0.46237545513272404 0.6193239752976292 0.594054787588091 +20 ENSG0000010001 Tgd 100241 A G chr20:100241:A:G -231119 0.9060509555091042 0.8299771024880875 0.3072916133198693 0.8773793045407222 +20 ENSG0000010001 Tgd 109405 C T chr20:109405:C:T 350110 0.6458597268227431 0.7974487585387153 0.04380594891794343 0.4137911570854856 +20 ENSG0000010001 Tgd 109099 T G chr20:109099:T:G -138647 0.13150506165011178 0.25709083884230655 0.9130997728141752 0.766225116382923 +20 ENSG0000010001 Tgd 106774 A T chr20:106774:A:T -2834 0.20218458626250535 0.31085462727350577 0.07683961216572599 0.21400417443957048 +20 ENSG0000010001 Tgd 101159 A C chr20:101159:A:C -151569 0.04540393616057237 0.35179500858994717 0.12296068167668328 0.6111630979916335 +20 ENSG0000010001 Tgd 103634 T A chr20:103634:T:A -8982 0.8924018613753462 0.21333575226977608 0.763297301287525 0.7908772067028556 +20 ENSG0000010001 Tgd 105898 G C chr20:105898:G:C 49472 0.7639408847787152 0.823856385364805 -0.32520978344444784 0.918477846847717 +20 ENSG0000010001 Tgd 106893 A G chr20:106893:A:G 403918 0.2730084954128682 0.5456700208442041 -0.9221644141475571 0.4298376585867766 +20 ENSG0000010001 Tgd 103175 T C chr20:103175:T:C 434276 0.29957572319320536 0.5419420190407322 -0.6095361330037943 0.30433609232831993 +20 ENSG0000010001 Tgd 102898 C T chr20:102898:C:T -98789 0.9211373402282391 0.7977936260979904 0.2612439538396474 0.849959846620391 +20 ENSG0000010001 Tgd 106651 T A chr20:106651:T:A -153081 0.333992496528275 0.4455160782955915 -0.11133299876731662 0.27742351858305364 +20 ENSG0000010001 Tgd 100822 G C chr20:100822:G:C -29205 0.6198746288982298 0.35243921786592614 -0.2715558415514092 0.3976688281096243 +20 ENSG0000010001 Tgd 103375 T A chr20:103375:T:A 122924 0.03401430354149748 0.936917337278325 0.8046266848692263 0.3252278949546291 +20 ENSG0000010001 Tgd 100697 G C chr20:100697:G:C 266110 0.02755634237887261 0.99011284560031 -0.7965666072147606 0.23433743013911051 +20 ENSG0000010001 Tgd 101366 A G chr20:101366:A:G 316745 0.5075103859707994 0.3879002339747154 0.20205403843939607 0.6869913889249973 +20 ENSG0000010001 Tgd 102332 A T chr20:102332:A:T -323640 0.6338459031566456 0.4061229058883097 0.24196501628978595 0.9194578769473286 +20 ENSG0000010001 Tgd 105164 C A chr20:105164:C:A 215745 0.1771264821157671 0.0006500325573146615 -0.8346139987280756 0.13609793202622705 +20 ENSG0000010001 Tgd 107172 T G chr20:107172:T:G 296442 0.812456024435431 0.9189728576747619 -0.8421201807333896 0.11188280381205178 +20 ENSG0000010001 Tgd 103516 T C chr20:103516:T:C 336708 0.6546763605355127 0.6863936080649535 -0.4807406598306516 0.6340827988662285 +20 ENSG0000010001 Tgd 105568 A G chr20:105568:A:G -203757 0.04382588681475541 0.8347535319053582 -0.80021387688838 0.4434993023461125 +20 ENSG0000010001 Tgd 103134 T G chr20:103134:T:G 123861 0.5507445339077522 0.9307503279586551 0.4165939799422551 0.5902973047151963 +20 ENSG0000010001 Tgd 106000 A T chr20:106000:A:T 198799 0.7509961115511774 0.06576285547125704 -0.9805545064424401 0.39327774706898455 +20 ENSG0000010001 Tgd 103543 C A chr20:103543:C:A -286863 0.6900293744896532 0.5789782115706614 -0.9939916092539707 0.3488615969190779 +20 ENSG0000010001 Tgd 100515 T G chr20:100515:T:G -452178 0.506482285347392 0.6987296936832661 0.5206341636808418 0.06534505566907399 +20 ENSG0000010001 Tgd 108893 C A chr20:108893:C:A -267865 0.990485650702873 0.3368107369579384 0.2307472469895997 0.8920149817026268 +20 ENSG0000010001 Tgd 108937 T C chr20:108937:T:C 219349 0.5670822064613372 0.1465079266257927 -0.27730802613612493 0.07159101747888628 +20 ENSG0000010001 Tgd 100972 G C chr20:100972:G:C -453770 0.7782939128238845 0.8954386207583241 0.9922318380919393 0.5014528863786818 +20 ENSG0000010001 Tgd 102054 C T chr20:102054:C:T -478493 0.002779084389138986 0.4907765124624689 -0.24604609968121682 0.8482181806092323 +20 ENSG0000010001 Tgd 102576 A T chr20:102576:A:T -331515 0.6328831042940828 0.8284422681559189 -0.8542429284270068 0.21330405192362387 +20 ENSG0000010001 Tgd 106218 T G chr20:106218:T:G -307435 0.28586906273490087 0.4593785072657385 -0.49045766616209985 0.5825308405688938 +20 ENSG0000010001 Tgd 103061 T C chr20:103061:T:C -152890 0.8560114659015008 0.06974400591279073 0.47445754390142736 0.032916346726911926 +20 ENSG0000010001 Tgd 100653 G A chr20:100653:G:A -126530 0.2442852929653122 0.637206724020134 0.9181504628213324 0.5562300780833584 +20 ENSG0000010001 Tgd 106784 C T chr20:106784:C:T -485379 0.15146680836676385 0.9028529160965104 -0.8232275041337895 0.3931894950391928 +20 ENSG0000010001 Tgd 103604 T A chr20:103604:T:A -204732 0.8963847136373689 0.33451173422998015 0.9505523878861906 0.9121826730451137 +20 ENSG0000010001 Tgd 105474 G C chr20:105474:G:C 398849 0.5655936588399392 0.18606804376637065 -0.6580161512878675 0.7372097001746527 +20 ENSG0000010001 Tgd 106939 C T chr20:106939:C:T -85560 0.04642620854783919 0.9532512563702781 -0.5194612231987676 0.6713654290311243 +20 ENSG0000010001 Tgd 102936 A T chr20:102936:A:T -20200 0.37004399563165835 0.520660751957734 -0.844524633052431 0.46248180174320974 +20 ENSG0000010001 Tgd 107592 A T chr20:107592:A:T -498850 0.9073309037455742 0.11453443833316934 0.6023062071837819 0.8420118704135756 +20 ENSG0000010001 Tgd 103698 A T chr20:103698:A:T -301772 0.4314490832419994 0.9574352142829335 -0.8020506851816935 0.7954664313672961 +20 ENSG0000010001 Tgd 102801 A C chr20:102801:A:C 450958 0.9103857690426179 0.7856763461566935 0.04450794417933701 0.9099509623970401 +20 ENSG0000010001 Tgd 100071 C A chr20:100071:C:A -45197 0.10641600767375936 0.11206456648657381 -0.12693905515319126 0.5359950170372199 +20 ENSG0000010001 Tgd 105445 A C chr20:105445:A:C 96613 0.7496246581058948 0.6902673838497106 -0.05910964060605495 0.7042737314853159 +20 ENSG0000010001 Tgd 101544 G A chr20:101544:G:A 243261 0.050343928861710796 0.9924152923608318 -0.32066124801087614 0.23709684688055105 +20 ENSG0000010001 Tgd 108766 T A chr20:108766:T:A 74083 0.9790894491630622 0.6086564879313472 -0.6908535881560995 0.908706255900134 +20 ENSG0000010001 Tgd 107858 T C chr20:107858:T:C -152189 0.9614449283634714 0.3109917407202172 -0.8931591114795725 0.0968785080793015 +20 ENSG0000010001 Tgd 108420 G T chr20:108420:G:T -498722 0.0539743391993065 0.5511998401116687 0.23008381269194977 0.5371179230312508 +20 ENSG0000010001 Tgd 103747 A C chr20:103747:A:C -407012 0.2774243077542231 0.48727469136866164 -0.44247775294134506 0.2122110933766598 +20 ENSG0000010001 Tgd 102158 G C chr20:102158:G:C 105316 0.6024434693942977 0.19628308490738855 -0.9795842368434928 0.12740645924943358 +20 ENSG0000010001 Tgd 100214 T A chr20:100214:T:A 164843 0.2078576458891893 0.050707670129822247 0.8742092358230666 0.6961826729708792 +20 ENSG0000010001 Tgd 103589 C T chr20:103589:C:T 229234 0.8758105196299807 0.2436992553839885 0.4357046662861599 0.04238740461031072 +20 ENSG0000010001 Tgd 102141 A G chr20:102141:A:G -148240 0.8863358799147221 0.4071579966952328 -0.20825423006651622 0.0038829526267926593 +20 ENSG0000010001 Tgd 100942 C T chr20:100942:C:T 480316 0.828176807164925 0.45691805675326924 -0.2882821500616721 0.9031902713550451 +20 ENSG0000010001 Tgd 101573 T A chr20:101573:T:A -64096 0.682636230315718 0.8129546767904439 0.9565604141696744 0.07495350681399385 +20 ENSG0000010001 Tgd 104892 G A chr20:104892:G:A 402405 0.944890254431377 0.5820403005858822 0.9115732987357068 0.2189515948087893 +20 ENSG0000010001 Tgd 100478 C T chr20:100478:C:T 383054 0.9653609003266248 0.5412122519402054 -0.448188601927745 0.6204686553233286 +20 ENSG0000010001 Tgd 106421 A T chr20:106421:A:T 484493 0.11851544245928192 0.4868478776066907 0.002174422977523127 0.36752559734476303 +20 ENSG0000010001 Tgd 109129 C G chr20:109129:C:G 382308 0.9697124653116701 0.3932562281228942 0.9080934189728336 0.8771359393971697 +20 ENSG0000010001 Tgd 100665 G T chr20:100665:G:T 234450 0.39400122262434323 0.1529716632076551 0.1406558828375486 0.8043776799687942 +20 ENSG0000010001 Tgd 104968 C A chr20:104968:C:A -37604 0.9653123202285556 0.3915162457503122 -0.6073056506386727 0.3068633969802744 +20 ENSG0000010001 Tgd 103090 T G chr20:103090:T:G -139511 0.008536139892793115 0.6472232312300682 -0.2461423699963865 0.4541617236851377 +20 ENSG0000010001 Tgd 102122 T G chr20:102122:T:G -358768 0.43383987905132915 0.8340233126094277 -0.8230806992125854 0.9686888148614108 +20 ENSG0000010001 Tgd 104190 T G chr20:104190:T:G 197790 0.13744543432917555 0.8287486489031015 -0.31295466511192416 0.6548914805222336 +20 ENSG0000010001 Tgd 105253 C T chr20:105253:C:T -393662 0.6791778021655014 0.8501503580304839 0.2724644375783851 0.9550048204902671 +20 ENSG0000010001 Tgd 108746 G A chr20:108746:G:A 275846 0.6227746749692049 0.4075639035367884 0.27894007027301293 0.7246305329488497 +20 ENSG0000010001 Tgd 101387 G C chr20:101387:G:C -268681 0.2010131967045785 0.3388354763761009 -0.5211561189985043 0.13484392492804864 +20 ENSG0000010001 Tgd 104616 G T chr20:104616:G:T 432145 0.36563329895370034 0.05760319057606533 0.06325750404373132 0.22568793358115144 +20 ENSG0000010001 Tgd 104272 T A chr20:104272:T:A 348210 0.6895243319935026 0.07754832564805125 0.41281166426023574 0.3664785011074777 +20 ENSG0000010001 Tgd 108668 A C chr20:108668:A:C 253682 0.2670761821403721 0.863567102453891 0.5567240376437337 0.3910139014215876 +20 ENSG0000010001 Tgd 109236 C G chr20:109236:C:G -153105 0.7960660342390194 0.40137663175781446 0.4242126926021945 0.7208314588046829 +20 ENSG0000010001 Tgd 104396 C T chr20:104396:C:T -121997 0.9670543390507188 0.4365861368977936 0.1286353390244861 0.9911370769842647 +20 ENSG0000010001 Tgd 104438 G A chr20:104438:G:A -48161 0.2086217396404204 0.2803571978693691 -0.8418426934319259 0.3439142910038318 +20 ENSG0000010001 Tgd 106062 A C chr20:106062:A:C -305631 0.7604178219966661 0.5959445472255004 -0.35380699058581344 0.9400114339578486 +20 ENSG0000010001 Tgd 109433 C G chr20:109433:C:G -309449 0.11284167210346874 0.9226379635894978 -0.9729075215280008 0.8702456336457771 +20 ENSG0000010001 Tgd 104525 C A chr20:104525:C:A -221399 0.18159265357856424 0.12253981033805883 0.627275456278253 0.05358649507685408 +20 ENSG0000010001 Tgd 104339 T G chr20:104339:T:G 356244 0.11634393260626064 0.7767515504116929 0.7722617880843023 0.2142774773662978 +20 ENSG0000010001 Tgd 100915 T G chr20:100915:T:G -263017 0.10424982727356658 0.9074603742410958 0.807333827288031 0.030957686786530495 +20 ENSG0000010001 Tgd 101999 G C chr20:101999:G:C 464430 0.16701220081812695 0.9319211924094501 -0.8411983494704913 0.7301595745342508 +20 ENSG0000010001 Tgd 107318 A C chr20:107318:A:C -166201 0.1564184144818429 0.36274810743067765 0.9389220276168213 0.28008079068649744 +20 ENSG0000010001 Tgd 102888 G A chr20:102888:G:A -382111 0.49722008551653885 0.6428158131604896 -0.6727987100229618 0.6484566443772991 +20 ENSG0000010001 Tgd 100415 G C chr20:100415:G:C 417831 0.7419718714084907 0.14758790450218606 0.8098745859371062 0.46333629145110683 +20 ENSG0000010001 Tgd 102164 C G chr20:102164:C:G -302553 0.1949792017640961 0.0034052961429589246 -0.44268530739804013 0.06288346053704459 +20 ENSG0000010001 Tgd 100765 C T chr20:100765:C:T 353196 0.43932838687620324 0.5370098953163758 -0.9508267800871795 0.9361148362764727 +20 ENSG0000010001 Tgd 105333 A T chr20:105333:A:T 7348 0.8563348627270642 0.17818140036976504 -0.7439528693897639 0.30987958088608286 +20 ENSG0000010001 Tgd 105240 G T chr20:105240:G:T -374260 0.4254226239507627 0.6042153187179857 -0.5465816711238094 0.5740906037808017 +20 ENSG0000010001 Tgd 102023 T G chr20:102023:T:G 54787 0.8061229856874534 0.694127761474584 -0.011245727636596703 0.16531394210848716 +20 ENSG0000010001 Tgd 100575 T A chr20:100575:T:A -292261 0.3780834572198567 0.3458632182409198 0.4183746003236575 0.5185793760254225 +20 ENSG0000010001 Tgd 106403 T A chr20:106403:T:A 130123 0.6448753341025637 0.5756134817470189 0.26233522379316665 0.4851550405868063 +20 ENSG0000010001 Tgd 104033 C T chr20:104033:C:T 254069 0.3735289049622431 0.6153702538628048 0.6544939859695926 0.8599470932678476 +20 ENSG0000010001 Tgd 103494 G T chr20:103494:G:T 233280 0.6159485965229876 0.8936214709446763 0.20677948903923804 0.17513202674256817 +20 ENSG0000010001 Tgd 104708 C G chr20:104708:C:G 224765 0.6934927391134613 0.8944019509979508 0.6631933036753463 0.7820768414712307 +20 ENSG0000010001 Tgd 103695 A C chr20:103695:A:C -463554 0.46954243180972344 0.09163803538231552 -0.9020901389237186 0.9761470493127077 +20 ENSG0000010001 Tgd 100747 T G chr20:100747:T:G 136626 0.4978342040472641 0.9596088984667746 0.5289824829349872 0.8071188564690689 +20 ENSG0000010001 Tgd 103276 G A chr20:103276:G:A -396537 0.014159467007161641 0.12468128767587927 -0.20714855045412972 0.35486653944225116 +20 ENSG0000010001 Tgd 109071 A G chr20:109071:A:G 198582 0.7937558207051046 0.6302668633665278 0.8460857675589839 0.7622827594569045 +20 ENSG0000010001 Tgd 108752 C G chr20:108752:C:G 1718 0.20030411574476836 0.44261622245424725 -0.47468879623675164 0.14600345806487175 +20 ENSG0000010001 Tgd 103551 T A chr20:103551:T:A 165573 0.10613057579384233 0.6074281952681908 -0.4924873859116692 0.15481469593763356 +20 ENSG0000010001 Tgd 109179 T C chr20:109179:T:C -75299 0.05715991092493333 0.1830404760021931 0.7768557014753286 0.9929098827024178 +20 ENSG0000010001 Tgd 105531 T C chr20:105531:T:C 187959 0.049308940024809345 0.3896113279628989 0.6662322565479402 0.6357962810811805 +20 ENSG0000010001 Tgd 107845 T A chr20:107845:T:A 396620 0.647754290064725 0.5315726403550942 -0.45688795452088504 0.6839905330701903 +20 ENSG0000010001 Tgd 108058 C A chr20:108058:C:A 367878 0.23631475870544394 0.4855668296590625 -0.3694893832636599 0.8569150814066202 +20 ENSG0000010001 Tgd 104996 A C chr20:104996:A:C -344290 0.013552053931941255 0.6599913393835507 -0.5604969147627301 0.3859814170624335 +20 ENSG0000010001 Tgd 106575 A C chr20:106575:A:C 196223 0.3992964716943994 0.5709105717254573 0.440190247796872 0.6571941230297806 +20 ENSG0000010001 Tgd 106327 A C chr20:106327:A:C 265982 0.2768488510754269 0.4761438969152638 -0.27693575146167815 0.2521756315835438 +20 ENSG0000010001 Tgd 101192 T A chr20:101192:T:A -113823 0.08647795340507514 0.9773539805440595 -0.4646637428995837 0.0784156720165923 +20 ENSG0000010001 Tgd 105607 C G chr20:105607:C:G -215187 0.016906988394077338 0.9333452185282504 -0.8173520330156092 0.7211756259992664 +20 ENSG0000010001 Tgd 109707 T C chr20:109707:T:C -27240 0.5471217520285483 0.3577527016762908 -0.6302744737237973 0.47768321744818004 +20 ENSG0000010001 Tgd 100009 T A chr20:100009:T:A -234060 0.16872727449682934 0.9763944011799671 0.3333270551995773 0.07204952611868526 +20 ENSG0000010001 Tgd 108129 A T chr20:108129:A:T 264374 0.6616323894992872 0.14967113962382816 -0.8534167864799387 0.20258355981858106 +20 ENSG0000010001 Tgd 103992 G A chr20:103992:G:A 93907 0.9548910671712446 0.47456646871283226 -0.8516132956002105 0.42693608864440724 +20 ENSG0000010001 Tgd 107928 T A chr20:107928:T:A 336648 0.601942121871486 0.7704912363393178 -0.7362967813335493 0.6523822810725423 +20 ENSG0000010001 Tgd 100464 G C chr20:100464:G:C 229235 0.5767756250786388 0.5304178858903434 0.24327488951614962 0.6490995939385289 +20 ENSG0000010001 Tgd 106888 C T chr20:106888:C:T 381495 0.637402459501992 0.20800486907887916 0.26193040139880464 0.5720941494495355 +20 ENSG0000010001 Tgd 105059 T A chr20:105059:T:A 131890 0.0916955145445858 0.7699633939730468 -0.34236865775634806 0.1891877230021829 +20 ENSG0000010001 Tgd 108397 C T chr20:108397:C:T -255499 0.12468921500989583 0.04568068801268588 -0.7578972341702357 0.07018382913336799 +20 ENSG0000010001 Tgd 100386 C G chr20:100386:C:G 346781 0.3781359290502029 0.9931873178689798 0.12608071625357664 0.45663871257559474 +20 ENSG0000010001 Tgd 104655 G A chr20:104655:G:A 245502 0.04994166643314513 0.14028045848656356 0.936339148301816 0.46480294490790053 +20 ENSG0000010001 Tgd 105017 C G chr20:105017:C:G 20525 0.40091369522917175 0.5723958570348179 0.1861717171987729 0.9234338859185575 +20 ENSG0000010001 Tgd 101459 G T chr20:101459:G:T -95610 0.8905263867047334 0.4266304127173588 0.9812154029872227 0.25767463307859784 +20 ENSG0000010001 Tgd 105417 G T chr20:105417:G:T -129850 0.31473472490185195 0.2205907961000485 -0.6016403133029484 0.5892744479430889 +20 ENSG0000010001 Tgd 106327 C G chr20:106327:C:G 146403 0.18647147687439658 0.46440306634738615 -0.8418436332060404 0.8828491798889244 +20 ENSG0000010001 Tgd 109265 C T chr20:109265:C:T 96964 0.695945437104679 0.22274016083103576 -0.5882226966389215 0.6950267714157012 +20 ENSG0000010001 Tgd 109725 G A chr20:109725:G:A -312047 0.36800684295419284 0.11012195916110268 0.05803239585611619 0.4632098695942159 +20 ENSG0000010001 Tgd 103382 G C chr20:103382:G:C -253826 0.9874481415626639 0.8533253693134603 0.22816303804488292 0.9162489745691101 +20 ENSG0000010001 Tgd 109169 C G chr20:109169:C:G -134382 0.9226032441980613 0.41394750518693846 -0.13075093555430062 0.29923856801094306 +20 ENSG0000010001 Tgd 105414 T C chr20:105414:T:C 243478 0.25739786614153226 0.07299393260260756 0.7933757052623109 0.6123747258126061 +20 ENSG0000010001 Tgd 106481 G C chr20:106481:G:C -262587 0.5749199158021623 0.26963920054639445 -0.18016428852387745 0.018159023696919588 +20 ENSG0000010001 Tgd 109198 T A chr20:109198:T:A 122142 0.3281880058385749 0.4201282421373106 0.21087750379666725 0.47755101197825733 +20 ENSG0000010001 Tgd 103581 C A chr20:103581:C:A -238719 0.1576933272452007 0.9673381746409542 0.9954127206536563 0.7604885654928977 +20 ENSG0000010001 Tgd 107300 T A chr20:107300:T:A 224851 0.17333708789306523 0.8604212662483542 0.5233674353860576 0.47945125500482805 +20 ENSG0000010001 Tgd 104938 C T chr20:104938:C:T -198991 0.6302972563337934 0.7843690098285566 -0.25891194735947076 0.47314501452112606 +20 ENSG0000010001 Tgd 109595 A T chr20:109595:A:T -489346 0.04291073457726269 0.2781376657387986 -0.13432538735484245 0.30508228407889554 +20 ENSG0000010001 Tgd 101051 T C chr20:101051:T:C -388184 0.1363604201285924 0.11479874107271548 0.4676777253117328 0.46200946331758147 +20 ENSG0000010001 Tgd 106447 C G chr20:106447:C:G -300441 0.33076736764870784 0.3373818220794531 0.3550816303429436 0.4718819612330088 +20 ENSG0000010001 Tgd 100038 G A chr20:100038:G:A 467518 0.5736640886178906 0.2184008802800017 -0.8624313434795818 0.7061104553351977 +20 ENSG0000010001 Tgd 109053 C T chr20:109053:C:T -228026 0.6957629570905571 0.39654877325807725 -0.5574254678988149 0.07340650250464273 +20 ENSG0000010001 Tgd 108881 C A chr20:108881:C:A 428008 0.20470356417166735 0.8902488066521821 -0.6190125967738991 0.4079882887185644 +20 ENSG0000010001 Tgd 102224 A T chr20:102224:A:T -295630 0.31002737177550266 0.2927550910645097 -0.4697537361595412 0.2087043663141672 +20 ENSG0000010001 Tgd 101766 A C chr20:101766:A:C -256741 0.6632856909242439 0.7142056195396599 -0.16862956427880094 0.7417100629467761 +20 ENSG0000010001 Tgd 106493 C T chr20:106493:C:T 96724 0.8603554388923926 0.3814290967081728 0.16513340114449404 0.051072914010566725 +20 ENSG0000010001 Tgd 101470 C A chr20:101470:C:A -11557 0.26349596074464643 0.9935469928200533 -0.3958038507723911 0.8416309172974409 +20 ENSG0000010001 Tgd 100958 C A chr20:100958:C:A -328695 0.16198703508873824 0.5590845391862239 0.8886401099015908 0.42270218248257485 +20 ENSG0000010001 Tgd 105544 T G chr20:105544:T:G 288116 0.336774093880003 0.8721406441471852 0.84456315277183 0.16032357121833674 +20 ENSG0000010001 Tgd 103294 T A chr20:103294:T:A -357088 0.016241715360001074 0.33018905968422185 0.1472338138745204 0.10869932409607404 +20 ENSG0000010001 Tgd 103350 A T chr20:103350:A:T -476967 0.21945958731523574 0.2536388889572879 -0.06310794590453495 0.06865309274441868 +20 ENSG0000010001 Tgd 102013 C A chr20:102013:C:A -41207 0.8559027793025088 0.14199445229698504 -0.043223759387843286 0.6103511935101903 +20 ENSG0000010001 Tgd 105165 T A chr20:105165:T:A -318009 0.27799401165362403 0.37019510724104476 -0.8878999191784576 0.9416205681980252 +20 ENSG0000010001 Tgd 102836 T C chr20:102836:T:C 355705 0.48763624705841624 0.2349878030199064 -0.5664303560427841 0.7170221327467403 +20 ENSG0000010001 Tgd 102160 A T chr20:102160:A:T 66423 0.29600511087814463 0.06810137589684129 0.9444109022551017 0.5819461510605358 +20 ENSG0000010001 Tgd 100269 A G chr20:100269:A:G 252562 0.16304426608690492 0.16340658561823806 0.59413737255935 0.2933814058457841 +20 ENSG0000010001 Tgd 106117 A G chr20:106117:A:G 353880 0.8786740431354368 0.4135871448836611 0.662650946660988 0.6608932955132031 +20 ENSG0000010001 Tgd 108954 G A chr20:108954:G:A 372097 0.9173442756853033 0.6421931135361068 0.38196764134157046 0.3217938112990217 +20 ENSG0000010001 Tgd 104268 G A chr20:104268:G:A 152527 0.7866597386628735 0.6007202113845586 0.7245310423206794 0.925733649003848 +20 ENSG0000010001 Tgd 100820 G C chr20:100820:G:C 170898 0.5416239889516681 0.536822936478236 0.8409963911877012 0.15493207739167786 +20 ENSG0000010001 Tgd 107687 T C chr20:107687:T:C 30358 0.8722098464603277 0.06408900901584857 -0.6888963234922605 0.5991984052066739 +20 ENSG0000010001 Tgd 109584 C G chr20:109584:C:G -86649 0.7582494507266319 0.28174742097118155 -0.49055507905992735 0.5076261027305005 +20 ENSG0000010001 Tgd 102416 T G chr20:102416:T:G -238796 0.6272010519178695 0.4513695133731024 0.5388419470263806 0.07723283382233027 +20 ENSG0000010001 Tgd 103053 A T chr20:103053:A:T -411358 0.0859526766786457 0.04714627652783543 0.06183170464470389 0.9660442511662782 +20 ENSG0000010001 Tgd 100688 T C chr20:100688:T:C 221797 0.5527989150280405 0.8073424169288068 0.4854945631949714 0.05094662282571205 +20 ENSG0000010001 Tgd 101212 G A chr20:101212:G:A 404872 0.8243791646117811 0.29134804527153035 -0.9278926730463246 0.6296502440616478 +20 ENSG0000010001 Tgd 103696 T C chr20:103696:T:C -391401 0.5877569539220959 0.6194263593647668 -0.496361692332552 0.35560468605924095 +20 ENSG0000010001 Tgd 109801 C A chr20:109801:C:A 17987 0.10202366242307037 0.17550288991708285 0.8106320722733436 0.9454011012868778 +20 ENSG0000010001 Tgd 104171 G T chr20:104171:G:T -328506 0.021464015250776347 0.8571550122593445 -0.7006929644295281 0.11387388603616354 +20 ENSG0000010001 Tgd 102887 G C chr20:102887:G:C 218378 0.8109088708510479 0.5911026066472386 0.29209796164185 0.8501473811950974 +20 ENSG0000010001 Tgd 103152 T A chr20:103152:T:A 225987 0.5395784662399736 0.195502014475738 0.9523239476963397 0.29513321534350423 +20 ENSG0000010001 Tgd 107256 A C chr20:107256:A:C 26598 0.8406178244841466 0.4990957491738689 0.19844063490793995 0.9225261814837383 +20 ENSG0000010001 Tgd 100193 C G chr20:100193:C:G -478180 0.8044394863114513 0.010324395151297683 -0.2516179589353553 0.6834334414686682 +20 ENSG0000010001 Tgd 108315 C A chr20:108315:C:A 141809 0.7660887157541213 0.31322180620928464 0.5760457170288413 0.4487468488837656 +20 ENSG0000010001 Tgd 104217 T G chr20:104217:T:G -52113 0.6346608374858843 0.20920307308404384 0.8952572923548243 0.5981349285642789 +20 ENSG0000010001 Tgd 105187 G T chr20:105187:G:T -218974 0.18498652765416002 0.9212819002420316 -0.05166939915855573 0.7949956129217584 +20 ENSG0000010001 Tgd 102622 C T chr20:102622:C:T -481612 0.4183608597558245 0.885822254414614 -0.30142063583825607 0.08463124065561677 +20 ENSG0000010001 Tgd 109906 T A chr20:109906:T:A 185894 0.36888543943095664 0.7251277486044648 -0.6846641726656353 0.5929366357293107 +20 ENSG0000010001 Tgd 101918 A C chr20:101918:A:C 468947 0.8646853711832332 0.9289370534465083 -0.1789745655899302 0.04299946996184526 +20 ENSG0000010001 Tgd 109690 G T chr20:109690:G:T -42935 0.24436375098878405 0.6683750653281922 0.624728041204353 0.6461068517654907 +20 ENSG0000010001 Tgd 102824 C T chr20:102824:C:T -455179 0.43146445137994893 0.07599778723138939 0.32649065940393407 0.6238788751502162 +20 ENSG0000010001 Tgd 100444 C A chr20:100444:C:A -296019 0.20476271751412267 0.10696914958235093 0.3094025632487203 0.7605228357499981 +20 ENSG0000010001 Tgd 100663 A C chr20:100663:A:C 101774 0.5344326932107482 0.8509914519224281 0.4087449588706966 0.15787688684588747 +20 ENSG0000010001 Tgd 101372 A T chr20:101372:A:T 320102 0.07626944312537598 0.7491832844620385 0.022723595242891692 0.9117848260369326 +20 ENSG0000010001 Tgd 101846 C T chr20:101846:C:T 411978 0.43544021653711695 0.4171563724859465 -0.0009929241026351843 0.402061928224983 +20 ENSG0000010001 Tgd 100139 A G chr20:100139:A:G -175672 0.9888218142509065 0.7500766004142553 0.6743433451178693 0.6740456122976469 +20 ENSG0000010001 Tgd 100698 G T chr20:100698:G:T 97706 0.9280686490422198 0.9155662799808227 -0.0043439650201178015 0.6386426659963502 +20 ENSG0000010001 Tgd 107872 T C chr20:107872:T:C 46078 0.32729223203613145 0.736748955844065 -0.22456642034939112 0.40232487900173064 +20 ENSG0000010001 Tgd 106543 C A chr20:106543:C:A 124734 0.4353444108681416 0.1293011770971978 -0.40761140497767934 0.18111230713636625 +20 ENSG0000010001 Tgd 102309 G T chr20:102309:G:T -312257 0.07510371650239778 0.18302173180213377 -0.38872345253561424 0.0648998818652828 +20 ENSG0000010001 Tgd 104659 T C chr20:104659:T:C 57734 0.21695816364763432 0.972580247467517 -0.43719098370166254 0.48611195285412107 +20 ENSG0000010001 Tgd 108374 T G chr20:108374:T:G 116696 0.6094103648816157 0.9767642290366162 -0.44462983942974654 0.6909640368172459 +20 ENSG0000010001 Tgd 101582 A T chr20:101582:A:T 417696 0.431990984247985 0.4098213391075787 0.4750009430675042 0.7453809214452163 +20 ENSG0000010001 Tgd 100035 C T chr20:100035:C:T 284330 0.161293652201007 0.33666055793607075 0.0879436492328296 0.189363506228441 +20 ENSG0000010001 Tgd 101579 A C chr20:101579:A:C 162499 0.04641325270114427 0.8096131099720331 -0.4596944116909536 0.8864096226761541 +20 ENSG0000010001 Tgd 103850 A C chr20:103850:A:C 80020 0.68911246330916 0.9249048338676232 0.684902560864638 0.6163285019602266 +20 ENSG0000010001 Tgd 109250 G T chr20:109250:G:T 362595 0.4573886376342662 0.4361477340278207 -0.5118687472076033 0.22791127788374635 +20 ENSG0000010001 Tgd 109107 T G chr20:109107:T:G 205875 0.7896037838068898 0.9597385615396994 -0.5710196820712483 0.48416853277460875 +20 ENSG0000010001 Tgd 101365 C A chr20:101365:C:A 426178 0.6311059591433038 0.542331024356566 0.6226505301899095 0.8273243315755998 +20 ENSG0000010001 Tgd 106595 T G chr20:106595:T:G -23029 0.10475485211485736 0.43405344003550683 -0.3905944084356392 0.7771945110675059 +20 ENSG0000010001 Tgd 100014 A T chr20:100014:A:T -337416 0.6638240106839052 0.7911019411448484 -0.5977498307813864 0.22638322219386217 +20 ENSG0000010001 Tgd 109975 T A chr20:109975:T:A 205719 0.5405642602529277 0.508101811491622 0.941632914897885 0.349978288015826 +20 ENSG0000010001 Tgd 103062 G A chr20:103062:G:A 54020 0.4768707180423053 0.7082470725319949 0.5285076906723258 0.9410335642368861 +20 ENSG0000010001 Tgd 100325 G C chr20:100325:G:C 365622 0.5820011732507359 0.006273944935232811 0.7977079143275674 0.5386880393633546 +20 ENSG0000010001 Tgd 101646 C T chr20:101646:C:T 307743 0.0750603573111438 0.1274356578818625 0.21339759893111387 0.9565659676666691 +20 ENSG0000010001 Tgd 101914 G A chr20:101914:G:A -130542 0.969936986218548 0.4189992515709653 0.7064575930422694 0.6436082513608251 +20 ENSG0000010001 Tgd 108865 G T chr20:108865:G:T 270099 0.6755569354939185 0.9906757527305966 0.6438172866684844 0.15152461926485378 +20 ENSG0000010001 Tgd 106403 G C chr20:106403:G:C 229736 0.9533410282580205 0.3992537746866537 -0.23105557614983074 0.17164411357062992 +20 ENSG0000010001 Tgd 105799 A T chr20:105799:A:T -160605 0.4482173711369932 0.30804789525823784 0.014459603923210551 0.5659388967098148 +20 ENSG0000010001 Tgd 102663 T C chr20:102663:T:C 203764 0.435155314417739 0.6364619360047017 0.5279925531795269 0.7384359387573872 +20 ENSG0000010001 Tgd 102237 A G chr20:102237:A:G -218859 0.6274015789864921 0.1427193862559808 0.23468509930380765 0.4236283103054419 +20 ENSG0000010001 Tgd 104990 A G chr20:104990:A:G 101981 0.6187358900633251 0.4844312147914892 0.1248717308617715 0.5536925503318386 +20 ENSG0000010001 Tgd 109754 G C chr20:109754:G:C 219324 0.6797156669052729 0.2549101006921378 -0.2961133318307412 0.6181891257744849 +20 ENSG0000010001 Tgd 109355 C G chr20:109355:C:G -210804 0.07526797021633624 0.5090589388723764 0.6054554076233889 0.8021806772169789 +20 ENSG0000010001 Tgd 104953 A G chr20:104953:A:G -15513 0.24253186798822324 0.8388956968362297 0.03797510182446073 0.6302838361190208 +20 ENSG0000010001 Tgd 103380 G A chr20:103380:G:A -100681 0.2929672954708764 0.5842798913546219 -0.9440912415799336 0.2907257436791141 +20 ENSG0000010001 Tgd 100162 T G chr20:100162:T:G 418383 0.009912761499486944 0.9648525802113216 -0.7634648556158803 0.887742117543508 +20 ENSG0000010001 Tgd 102287 G A chr20:102287:G:A -84022 0.40021476365534947 0.5528769463436999 0.8034636089385532 0.019060106240417152 +20 ENSG0000010001 Tgd 108919 T C chr20:108919:T:C 60612 0.8335638214101095 0.3585692608362694 -0.7912506942425306 0.22221808596360842 +20 ENSG0000010001 Tgd 109115 T A chr20:109115:T:A -154096 0.48246760893703444 0.6667572916656994 0.0817142062047902 0.23772422935244072 +20 ENSG0000010001 Tgd 109749 G C chr20:109749:G:C 373891 0.854610441204256 0.9948434614091091 0.10666442435432932 0.4165780465100984 +20 ENSG0000010001 Tgd 103876 A T chr20:103876:A:T 470409 0.9601313430598243 0.7883027894091457 0.8303971441496216 0.048196053807670156 +20 ENSG0000010001 Tgd 103488 A C chr20:103488:A:C 255188 0.3903773334605417 0.678825157905348 -0.796354970452579 0.8887159311441281 +20 ENSG0000010001 Tgd 109773 C T chr20:109773:C:T -481873 0.9111604688185523 0.950315567533943 -0.22519486706280945 0.0979943118870272 +20 ENSG0000010001 Tgd 104278 T G chr20:104278:T:G 67659 0.6649664479842091 0.8972026556024508 -0.4116205806733191 0.4493766796433385 +20 ENSG0000010001 Tgd 100849 G A chr20:100849:G:A 185378 0.11831515677883842 0.4721040886789223 -0.1711092162402441 0.6430963170218633 +20 ENSG0000010001 Tgd 100573 T G chr20:100573:T:G -109551 0.8885555989141176 0.12287524378005743 -0.5381476093622548 0.9190150558302609 +20 ENSG0000010001 Tgd 104965 C T chr20:104965:C:T 130669 0.5953060085933095 0.04326585973348207 -0.032104070868212986 0.6655998877704229 +20 ENSG0000010001 Tgd 106914 G C chr20:106914:G:C -327159 0.30088347896932444 0.038619364632888176 -0.716473239848056 0.7783406415724752 +20 ENSG0000010001 Tgd 101915 T C chr20:101915:T:C 477733 0.42547020888416764 0.1782604320662975 0.8778814204798397 0.1816192364898271 +20 ENSG0000010001 Tgd 109978 A C chr20:109978:A:C -252629 0.21545485356353322 0.635202271100255 0.31981303237222436 0.44013724862288733 +20 ENSG0000010001 Tgd 100482 C G chr20:100482:C:G -177770 0.48040031567787056 0.3887976356116979 0.08236770761867906 0.685049563882365 +20 ENSG0000010001 Tgd 105336 C T chr20:105336:C:T 129965 0.4370734045375704 0.17072245550445386 0.6962063286317806 0.8179633783588446 +20 ENSG0000010001 Tgd 108756 T C chr20:108756:T:C -493597 0.4890989127042643 0.08183566458112856 -0.7256402330477558 0.33368392050210754 +20 ENSG0000010001 Tgd 105697 T A chr20:105697:T:A -325702 0.701516783452775 0.8618527643343121 0.19186408901745966 0.0043209812662102 +20 ENSG0000010001 Tgd 104082 G T chr20:104082:G:T 190395 0.1848348747678462 0.09140457906215094 0.7378431121705391 0.9293664208457918 +20 ENSG0000010001 Tgd 107739 T G chr20:107739:T:G 309921 0.2706999446158983 0.6425380523918405 0.4630128032919878 0.6178680179503452 +20 ENSG0000010001 Tgd 109105 C T chr20:109105:C:T -310266 0.5844559346779687 0.3052738396101532 0.3625356978431067 0.3469290627449986 +20 ENSG0000010001 Tgd 105123 A G chr20:105123:A:G -378726 0.9774983637210509 0.3276917374823506 -0.2635132131733331 0.08494936231656403 +20 ENSG0000010001 Tgd 101091 A C chr20:101091:A:C 460744 0.05222543723205475 0.8516794788593953 -0.9056727832068086 0.30920531081175096 +20 ENSG0000010001 Tgd 101520 C G chr20:101520:C:G -23834 0.30725631318423896 0.4716159271472772 0.5293715352732162 0.6389899452523076 +20 ENSG0000010001 Tgd 105843 T C chr20:105843:T:C -40346 0.8738450372884005 0.7318001370381556 0.7063496668971876 0.296500799752942 +20 ENSG0000010001 Tgd 107558 A C chr20:107558:A:C 108783 0.3002802558416712 0.8057776539026371 0.14215213745031252 0.2002393585867994 +20 ENSG0000010001 Tgd 104742 T A chr20:104742:T:A -150437 0.23136800891407117 0.5105451087230115 -0.9394296672605644 0.19604048697417187 +20 ENSG0000010001 Tgd 108682 T G chr20:108682:T:G -412816 0.8738469242119439 0.06864767289445428 -0.5979215169005705 0.8256727894221652 +20 ENSG0000010001 Tgd 108539 T G chr20:108539:T:G 481822 0.037434566862731056 0.4744342677744299 0.06989578738248992 0.17590749527717353 +20 ENSG0000010001 Tgd 109123 A C chr20:109123:A:C 332992 0.1740882879489587 0.5433050578476327 -0.6074014900677998 0.28595577295409674 +20 ENSG0000010001 Tgd 109091 G T chr20:109091:G:T -168682 0.6842712094083047 0.3134609325344806 -0.7555457287256371 0.691817992921351 +20 ENSG0000010001 Tgd 106695 C T chr20:106695:C:T 471591 0.3274376148651431 0.22642619522385976 0.6243355990317017 0.7844646806295664 +20 ENSG0000010001 Tgd 107838 T C chr20:107838:T:C -207221 0.8693565307670528 0.49656402384953446 0.4704413336394848 0.4432503894758556 +20 ENSG0000010001 Tgd 106208 T G chr20:106208:T:G 117454 0.9321424369909197 0.9869369291543337 -0.551032212229071 0.8138190001298318 +20 ENSG0000010001 Tgd 102238 C G chr20:102238:C:G 159664 0.793866779133764 0.2619931248699783 0.8120703748085356 0.05360562847541115 +20 ENSG0000010001 Tgd 109627 C G chr20:109627:C:G -261056 0.5774394424033306 0.5312917150998178 -0.5320949132344082 0.9311925925468979 +20 ENSG0000010001 Tgd 105577 T A chr20:105577:T:A 238482 0.0849843810521258 0.5944509760260488 0.32714224639635114 0.29121887030972166 +20 ENSG0000010001 Tgd 104711 T C chr20:104711:T:C -91200 0.27693535190912 0.9378830083802325 0.5529579746231854 0.2982432625937009 +20 ENSG0000010001 Tgd 107501 C G chr20:107501:C:G -321012 0.5610400059136648 0.8768417117814366 0.6477704312671768 0.8899431069402993 +20 ENSG0000010001 Tgd 105384 C T chr20:105384:C:T 491373 0.5183127279720996 0.11116187902232266 0.18467152195188596 0.17997096292909798 +20 ENSG0000010001 Tgd 101171 A T chr20:101171:A:T -186225 0.5288162793252461 0.18753143131209715 0.21687178175604194 0.8600192156538468 +20 ENSG0000010001 Tgd 101343 G A chr20:101343:G:A 471222 0.3281661998526212 0.5805994982206888 -0.40150259560489543 0.9655207665222095 +20 ENSG0000010001 Tgd 105386 A C chr20:105386:A:C 333413 0.925964841292133 0.4254540540005247 0.5210988651789521 0.1607160870920807 +20 ENSG0000010001 Tgd 106410 A T chr20:106410:A:T 53819 0.502777489585571 0.7519855010093556 0.6978425612505683 0.11496286359120415 +20 ENSG0000010001 Tgd 101343 T G chr20:101343:T:G 374818 0.5387705868466672 0.2751022424195706 0.8328711887681388 0.5768613038610305 +20 ENSG0000010001 Tgd 100372 T A chr20:100372:T:A -33075 0.46801032555917044 0.04699407793884369 -0.36875420588542585 0.5607137447862447 +20 ENSG0000010001 Tgd 106967 G T chr20:106967:G:T -268254 0.8231126426854628 0.37366882033221616 0.25600826485542805 0.6573359589261404 +20 ENSG0000010001 Tgd 108268 A G chr20:108268:A:G 285385 0.011888733273760943 0.8361345206866857 -0.36316618032516734 0.1274099942718536 +20 ENSG0000010001 Tgd 106465 A T chr20:106465:A:T 325506 0.5844930267320589 0.010435232882349044 0.9170518943317085 0.533105621908043 +20 ENSG0000010001 Tgd 109397 G C chr20:109397:G:C -359071 0.6463183080117372 0.31514911614031893 -0.7574748360611603 0.7237834386241832 +20 ENSG0000010001 Tgd 100693 A C chr20:100693:A:C 366492 0.535011491161593 0.10106433075357413 0.004576976853293946 0.12389392194653878 +20 ENSG0000010001 Tgd 104644 C A chr20:104644:C:A 422033 0.13562900796038546 0.21217741604621443 -0.07792292227470776 0.4010604608253323 +20 ENSG0000010001 Tgd 105624 G T chr20:105624:G:T -102470 0.7575259983692838 0.139860905073677 -0.12025840462944082 0.21781592627999857 +20 ENSG0000010001 Tgd 105713 G T chr20:105713:G:T -280863 0.3532298523336238 0.7984791518649604 -0.8792927160216197 0.008107285767828584 +20 ENSG0000010001 Tgd 105471 C G chr20:105471:C:G -405264 0.36671805108241073 0.95562637814804 -0.09927447638423548 0.24706394680486818 +20 ENSG0000010001 Tgd 105478 T G chr20:105478:T:G 95695 0.18593739239177365 0.3467173560697876 0.7544414865328395 0.10216072912105188 +20 ENSG0000010001 Tgd 104755 T G chr20:104755:T:G 211818 0.6134443211748252 0.6600246364923114 0.676638327659042 0.9111025392915622 +20 ENSG0000010001 Tgd 107726 G T chr20:107726:G:T -20869 0.0281730357949459 0.15840795296953813 0.1890026840839416 0.9967716969172925 +20 ENSG0000010001 Tgd 106197 G A chr20:106197:G:A -140218 0.9141125921113342 0.29498526585913576 0.04248002294014097 0.37833327818237755 +20 ENSG0000010001 Tgd 104177 C A chr20:104177:C:A 356686 0.7047953805547778 0.4122086620073273 -0.9300761536761919 0.10573826393357201 +20 ENSG0000010001 Tgd 107567 C T chr20:107567:C:T -148977 0.5354132121219664 0.8181352811665347 0.8380922272743745 0.41018514842098386 +20 ENSG0000010001 Tgd 104352 A C chr20:104352:A:C -369516 0.03747341177545016 0.6692788195626177 0.09372587503824259 0.13623354814890423 +20 ENSG0000010001 Tgd 103507 A C chr20:103507:A:C -350358 0.4866063998617114 0.20853062288627533 -0.7313581863995355 0.8573578505113796 +20 ENSG0000010001 Tgd 101679 C G chr20:101679:C:G -378304 0.528868546746506 0.5790116133534664 0.18395534630102683 0.7944526815504074 +20 ENSG0000010001 Tgd 100355 G A chr20:100355:G:A -61288 0.49529710711637087 0.2601277283964494 0.5123429277623235 0.9175252862916614 +20 ENSG0000010001 Tgd 109943 A T chr20:109943:A:T -318457 0.5056563134236711 0.7635313708945828 -0.4435607651101876 0.6140524250912545 +20 ENSG0000010001 Tgd 107444 C A chr20:107444:C:A 397244 0.7069118636632672 0.8311581524568248 0.5338384707071075 0.5380999370132981 +20 ENSG0000010001 Tgd 107434 T G chr20:107434:T:G -370726 0.4535127525469813 0.8882659837346225 -0.9574540310829358 0.9678673931017028 +20 ENSG0000010001 Tgd 109058 G C chr20:109058:G:C 313338 0.7208432984774307 0.8289998995893805 -0.5938098534186651 0.9471639159773015 +20 ENSG0000010001 Tgd 109678 A G chr20:109678:A:G -284469 0.5483767127237713 0.4431874651603368 0.4948257857433591 0.9618387784917453 +20 ENSG0000010001 Tgd 103645 G C chr20:103645:G:C 297946 0.47489633001019893 0.01392456016987631 -0.49786221840540934 0.23331562696205577 +20 ENSG0000010001 Tgd 100139 C T chr20:100139:C:T 37553 0.8259046572217016 0.8733476580614681 0.938649252402664 0.18710341968689967 +20 ENSG0000010001 Tgd 102093 G T chr20:102093:G:T -134382 0.2645073740744911 0.16685874737716044 -0.920961545052682 0.2627041064556856 +20 ENSG0000010001 Tgd 102792 T A chr20:102792:T:A 140903 0.03485020789624127 0.65237286207154 -0.09957950619123457 0.13481655867632836 +20 ENSG0000010001 Tgd 104400 C A chr20:104400:C:A -479364 0.05659710397777029 0.6901412792112522 0.3789340941841175 0.83902679226883 +20 ENSG0000010001 Tgd 104459 A T chr20:104459:A:T -332689 0.27072259315275704 0.9978306351660423 -0.519603955146839 0.5512874655843026 +20 ENSG0000010001 Tgd 101234 A G chr20:101234:A:G 249298 0.6161256381091951 0.09879068251514056 0.26858356481189904 0.14529841452877354 +20 ENSG0000010001 Tgd 104540 G A chr20:104540:G:A 115914 0.7301897833897076 0.5580209379991102 -0.6979532875953793 0.39038481601313213 +20 ENSG0000010001 Tgd 104191 G T chr20:104191:G:T -307763 0.17745606879289677 0.07812862092149087 -0.007982166976006289 0.299248763767313 +20 ENSG0000010001 Tgd 102362 T C chr20:102362:T:C -485332 0.2650147291450331 0.8900739006243438 0.2913723539329909 0.21477093793614915 +20 ENSG0000010001 Tgd 106869 T C chr20:106869:T:C -98845 0.525840464469948 0.09921676432745352 -0.23703500307929182 0.051210257041575384 +20 ENSG0000010001 Tgd 100197 T G chr20:100197:T:G -29556 0.6944585714697668 0.16983521771498422 0.8685002316529611 0.1522949837986901 +20 ENSG0000010001 Tgd 100576 A C chr20:100576:A:C 317294 0.792422497544033 0.39092373023377736 0.6051752927020873 0.7217202603623748 +20 ENSG0000010001 Tgd 101149 C T chr20:101149:C:T -70850 0.9584361802317303 0.5833923893509602 -0.9800472060000278 0.4653814925575277 +20 ENSG0000010001 Tgd 109911 C A chr20:109911:C:A -437157 0.09577969085375082 0.24339500916422518 -0.33292329377956764 0.7981433899590575 +20 ENSG0000010001 Tgd 100202 A G chr20:100202:A:G -273311 0.6153359373024041 0.08947523824502934 0.5052704778118782 0.035572681357667925 +20 ENSG0000010001 Tgd 107397 T G chr20:107397:T:G 93883 0.04125644820365604 0.5093160902903526 0.7691989999349489 0.6554308903698451 +20 ENSG0000010001 Tgd 108121 C G chr20:108121:C:G 330836 0.11187466233069898 0.4959779613536547 0.13895884405350478 0.5476104935924361 +20 ENSG0000010001 Tgd 101121 G A chr20:101121:G:A -23121 0.25683532138461806 0.24487840687529971 -0.8924128415696266 0.9783924011182416 +20 ENSG0000010001 Tgd 101522 G A chr20:101522:G:A -348931 0.3423212184092679 0.21467383139855778 0.17542630836185946 0.7555734835058441 +20 ENSG0000010001 Tgd 102326 A C chr20:102326:A:C -180089 0.7419078187889817 0.4460776060658417 0.6851401101717403 0.883418628052728 +20 ENSG0000010001 Tgd 106158 A T chr20:106158:A:T 207162 0.18263155535359865 0.6415527956598246 -0.29375551170399383 0.09527900347429995 +20 ENSG0000010001 Tgd 102139 A G chr20:102139:A:G 131953 0.8183411829181607 0.7202000957518172 -0.951787114582787 0.9707039122838534 +20 ENSG0000010001 Tgd 102195 A G chr20:102195:A:G -461145 0.1314132370484523 0.10630063395926692 0.3348296748167292 0.3203494728887642 +20 ENSG0000010001 Tgd 108799 A T chr20:108799:A:T 344547 0.4298670481182083 0.8808422193274156 0.9867354446269281 0.703415572794156 +20 ENSG0000010001 Tgd 109940 G C chr20:109940:G:C 2235 0.556002597719132 0.791163711836995 0.8166018423537127 0.5141814381539079 +20 ENSG0000010001 Tgd 106903 G C chr20:106903:G:C -475217 0.5111718457132685 0.23072127579392487 0.6417287537060556 0.5579327540877849 +20 ENSG0000010001 Tgd 101452 G C chr20:101452:G:C 149814 0.8463707757536603 0.13062949542517976 -0.1256335630897354 0.04456848101542556 +20 ENSG0000010001 Tgd 106614 T G chr20:106614:T:G 137460 0.9619477445659209 0.6253272379030104 0.6672114461270047 0.7856376272194782 +20 ENSG0000010001 Tgd 103776 G C chr20:103776:G:C -29140 0.9445489119781846 0.03907269615061337 -0.6845593285967655 0.22477744026117152 +20 ENSG0000010001 Tgd 108648 G C chr20:108648:G:C -212354 0.4316934584639345 0.1480342053951017 0.7113659234304479 0.16900436623284326 +20 ENSG0000010001 Tgd 102728 T G chr20:102728:T:G 219657 0.9388004224191876 0.14838439871534648 -0.9709103649962008 0.9027597141528474 +20 ENSG0000010001 Tgd 100025 G T chr20:100025:G:T 331813 0.29169080960584226 0.7143172621284718 -0.193387754955336 0.24003342303745415 +20 ENSG0000010001 Tgd 101823 C A chr20:101823:C:A -74075 0.7983212173182526 0.023142655042149518 0.9098899492006594 0.8505443317610988 +20 ENSG0000010001 Tgd 106300 T G chr20:106300:T:G -288669 0.933818805640536 0.7421645584081797 0.16394453753909644 0.5324006072888217 +20 ENSG0000010001 Tgd 109457 G A chr20:109457:G:A -92938 0.008906383378632476 0.7951567078609411 -0.3263231918185716 0.54378334169092 +20 ENSG0000010001 Tgd 101347 C G chr20:101347:C:G -243158 0.040630460162924154 0.023057668815250287 0.1934504779567665 0.8413163606037825 +20 ENSG0000010001 Tgd 109659 C T chr20:109659:C:T -238862 0.4345620357896439 0.8903186179457684 0.4460250412677622 0.24507420364125934 +20 ENSG0000010001 Tgd 107302 A C chr20:107302:A:C -403042 0.662152801484831 0.5552959639263285 -0.26123995044376147 0.25987876323905856 +20 ENSG0000010001 Tgd 108213 T C chr20:108213:T:C -342629 0.9727784024042718 0.1891125711494831 -0.4804515271645806 0.8480165597503332 +20 ENSG0000010001 Tgd 100198 A C chr20:100198:A:C -286664 0.32394193681060623 0.239173511249826 -0.17425411327010676 0.030941355906659505 +20 ENSG0000010001 Tgd 105270 G C chr20:105270:G:C -202851 0.5820046655131188 0.7040536349515485 0.7264603734675343 0.43251049397271224 +20 ENSG0000010001 Tgd 102430 A T chr20:102430:A:T -220034 0.8812345761355938 0.7210177333357332 0.6202266237032286 0.7066336285488384 +20 ENSG0000010001 Tgd 108833 A T chr20:108833:A:T 465372 0.13777277359827056 0.22249220694108995 -0.10652328138852862 0.9225200515932653 +20 ENSG0000010001 Tgd 104735 A T chr20:104735:A:T 433948 0.39108204201414 0.033680696270454225 -0.30669876186851996 0.8873553284701537 +20 ENSG0000010001 Tgd 108141 T G chr20:108141:T:G -261553 0.789668626433184 0.35851100561897065 0.9418780236341564 0.4121742466409613 +20 ENSG0000010001 Tgd 102618 T C chr20:102618:T:C -23492 0.0173968449862395 0.2946592426835739 -0.6810592767632762 0.09560654412580923 +20 ENSG0000010001 Tgd 109176 T C chr20:109176:T:C -387611 0.5489520513727915 0.686618636687643 0.8765362213469041 0.6287134460919551 +20 ENSG0000010001 Tgd 105364 C A chr20:105364:C:A -199201 0.6655586277416167 0.8922542586742546 -0.7711554783080588 0.032675438581194094 +20 ENSG0000010001 Tgd 107613 A C chr20:107613:A:C -52814 0.40839850920089804 0.0537821060810465 -0.7444263463980318 0.24306064768768265 +20 ENSG0000010001 Tgd 102349 G A chr20:102349:G:A -468937 0.08973107280884884 0.8789786975505769 0.8147507187095437 0.20130332963634712 +20 ENSG0000010001 Tgd 102084 G A chr20:102084:G:A -132110 0.08957129810075048 0.029365067592739713 0.8088988552166811 0.9465573926107529 +20 ENSG0000010001 Tgd 106132 A G chr20:106132:A:G 271152 0.4293832215311094 0.7514300966642968 -0.5512232787054736 0.8150818341384228 +20 ENSG0000010001 Tgd 104237 C G chr20:104237:C:G 260643 0.04600349791828573 0.8753192596544437 0.31018312540209814 0.8939398195608126 +20 ENSG0000010001 Tgd 107206 G T chr20:107206:G:T 393523 0.6340130887914133 0.3828193532319174 0.9327857498102368 0.10796385655862979 +20 ENSG0000010001 Tgd 101444 C T chr20:101444:C:T -492824 0.3659509457589729 0.7191784958803779 0.5970991645145642 0.9830525080543224 +20 ENSG0000010001 Tgd 105065 G T chr20:105065:G:T -227923 0.23487844578714911 0.5583342683397421 -0.15628850336262357 0.4916778663931335 +20 ENSG0000010001 Tgd 106715 C A chr20:106715:C:A 285858 0.6793889412747144 0.8260501582834668 0.3363570116864749 0.18408960590397447 +20 ENSG0000010001 Tgd 107423 A G chr20:107423:A:G 388462 0.41830554383689433 0.8092398225324365 0.8698948078018782 0.9319504298276542 +20 ENSG0000010001 Tgd 106557 C A chr20:106557:C:A 471608 0.6214011600563009 0.44192979398276 0.9955795766229891 0.8524489353465425 +20 ENSG0000010001 Tgd 107242 A T chr20:107242:A:T 106266 0.06008952587181282 0.20769349009994875 -0.9699105316922154 0.4133681668489594 +20 ENSG0000010001 Tgd 101784 C G chr20:101784:C:G -184026 0.9735543142674448 0.12555407162974386 -0.37358598613598337 0.2726033558240781 +20 ENSG0000010001 Tgd 103433 C A chr20:103433:C:A -177838 0.7260582031255672 0.8787051345327548 0.5078000482678964 0.5481360704541802 +20 ENSG0000010001 Tgd 101810 T A chr20:101810:T:A -147387 0.7906299057394133 0.43282363447157013 -0.49444436126051494 0.7385165363435354 +20 ENSG0000010001 Tgd 105838 T C chr20:105838:T:C -230749 0.5748320503954195 0.17206753803187536 0.9397931158493371 0.6602648855020509 +20 ENSG0000010001 Tgd 104529 C A chr20:104529:C:A 303644 0.12372478918042285 0.6705806159247267 0.2249182238140346 0.7743359553021879 +20 ENSG0000010001 Tgd 108958 A T chr20:108958:A:T -13881 0.24907763304204822 0.8571745281568922 -0.14193100879338805 0.30741627729774973 +20 ENSG0000010001 Tgd 105528 C T chr20:105528:C:T 259185 0.0647728780525556 0.5168171918185609 0.1733729660715273 0.42035566984343153 +20 ENSG0000010001 Tgd 100381 C A chr20:100381:C:A -135813 0.8467422433073787 0.8165586747285463 0.9859266138634442 0.18256309211266725 +20 ENSG0000010001 Tgd 102638 T C chr20:102638:T:C -413743 0.8021472299561454 0.18648810868810528 0.7263797078923522 0.1193454003745677 +20 ENSG0000010001 Tgd 106578 A C chr20:106578:A:C 140995 0.7439741786648469 0.5278925852766927 -0.9916174289018567 0.9460221177375148 +20 ENSG0000010001 Tgd 108138 T A chr20:108138:T:A 248190 0.7299807864566149 0.87229505557743 -0.22989888410461878 0.9874668338551797 +20 ENSG0000010001 Tgd 103320 T A chr20:103320:T:A 232815 0.20164442885692835 0.5946745011711255 0.10151757043707299 0.5926344471594299 +20 ENSG0000010001 Tgd 109903 A C chr20:109903:A:C -465991 0.9383583963901276 0.20985660178820797 0.8379671713231023 0.47536902930943736 +20 ENSG0000010001 Tgd 101914 T A chr20:101914:T:A 286654 0.6898588500647395 0.7475385375239061 0.1793880138193915 0.4671681361732308 +20 ENSG0000010001 Tgd 109090 G A chr20:109090:G:A 318596 0.7492150150609186 0.8846261026735674 0.515340795933511 0.8842219855218049 +20 ENSG0000010001 Tgd 102550 C A chr20:102550:C:A 256818 0.5073267464218326 0.09852217571313981 0.2960283500685592 0.845555602790449 +20 ENSG0000010001 Tgd 107646 A T chr20:107646:A:T -41197 0.34072611647439655 0.33769713737151874 -0.6687030537997365 0.1202604760051606 +20 ENSG0000010001 Tgd 107743 T G chr20:107743:T:G 47971 0.7446773723025851 0.47167385472060597 0.5587792466280161 0.5991455569020833 +20 ENSG0000010001 Tgd 100922 T G chr20:100922:T:G -382611 0.9454934106432032 0.10578362216615655 -0.9450192518156051 0.690569156329883 +20 ENSG0000010001 Tgd 101820 G T chr20:101820:G:T -363918 0.8937572777480081 0.6768461063185475 0.7582305335725557 0.5884905664779955 +20 ENSG0000010001 Tgd 106295 C G chr20:106295:C:G 14232 0.7748939329431538 0.5354738324729016 -0.02967068048048027 0.837663765530723 +20 ENSG0000010001 Tgd 100661 T C chr20:100661:T:C 73602 0.014924352420392695 0.7227948212349268 0.09808195183182344 0.7845937507565773 +20 ENSG0000010001 Tgd 107628 T C chr20:107628:T:C 201633 0.8681265733626501 0.19415465592147818 0.5360647311054683 0.214073990810384 +20 ENSG0000010001 Tgd 106476 A G chr20:106476:A:G 113501 0.03805143974231184 0.9933141945634169 0.2049296448959359 0.7636549385863859 +20 ENSG0000010001 Tgd 109036 C G chr20:109036:C:G -227809 0.3984107871829107 0.47215980306210437 -0.2221329092853217 0.4430415273573846 +20 ENSG0000010001 Tgd 105842 A G chr20:105842:A:G 149848 0.6900935405373139 0.24590781761753688 0.6994089332601836 0.9144762919812383 +20 ENSG0000010001 Tgd 105975 T A chr20:105975:T:A -162512 0.05491871189922004 0.11544007687814206 -0.1868554220400882 0.2988936001556216 +20 ENSG0000010001 Tgd 102379 G A chr20:102379:G:A -495374 0.4803427228908512 0.009646186363589826 -0.6047501062753995 0.04737424277697421 +20 ENSG0000010001 Tgd 108564 C T chr20:108564:C:T -204229 0.8485346228769518 0.7028162758652686 0.3896762894467447 0.6203827776138141 +20 ENSG0000010001 Tgd 103640 T C chr20:103640:T:C 68149 0.8552794552805641 0.5033892174509049 -0.5592187043490249 0.01120867931936934 +20 ENSG0000010001 Tgd 101756 G A chr20:101756:G:A 353590 0.015470276150053808 0.8581516536223378 -0.9062985606884941 0.10183306756565455 +20 ENSG0000010001 Tgd 101168 C G chr20:101168:C:G 232205 0.2908016473373761 0.7129151358767444 -0.5098639394180717 0.6680788559009747 +20 ENSG0000010001 Tgd 105407 T C chr20:105407:T:C 76665 0.09071522275710397 0.003140265687194721 -0.9658480313392672 0.119373052884519 +20 ENSG0000010001 Tgd 104525 C T chr20:104525:C:T 14414 0.5055643455703771 0.8083848102778777 0.5744759950710279 0.8556672064229626 +20 ENSG0000010001 Tgd 102004 C G chr20:102004:C:G -241231 0.5518095294904711 0.32095161635026326 0.5298367427944255 0.8643631428856844 +20 ENSG0000010001 Tgd 102242 A G chr20:102242:A:G 451695 0.49267929292854507 0.807180003065471 -0.7320271844534545 0.5926830563749662 +20 ENSG0000010001 Tgd 109221 G A chr20:109221:G:A -142052 0.3622805868059198 0.15476447624251644 0.7081638565493862 0.639852319922811 +20 ENSG0000010001 Tgd 109807 G T chr20:109807:G:T -261887 0.7343519954633145 0.018860780846389202 -0.40872839410948925 0.2934260600335638 +20 ENSG0000010001 Tgd 106059 C G chr20:106059:C:G 310721 0.46257598302188374 0.1413464250913148 -0.2837939103743754 0.4421014036137154 +20 ENSG0000010001 Tgd 100448 G T chr20:100448:G:T -435884 0.8269100673499722 0.46384526880460264 -0.27669239961692593 0.8057034567617689 +20 ENSG0000010001 Tgd 107876 T G chr20:107876:T:G 196862 0.7226600949555742 0.21651303095894026 -0.026648039846864924 0.3075887253412711 +20 ENSG0000010001 Tgd 103740 A T chr20:103740:A:T 431835 0.4423004932441327 0.8213379463024136 0.6810732528822736 0.5037516120808533 +20 ENSG0000010001 Tgd 105314 G T chr20:105314:G:T -98058 0.049810537412745104 0.5626224888321631 -0.33533842474877606 0.7708072384893078 +20 ENSG0000010001 Tgd 106463 G T chr20:106463:G:T 436905 0.4508682503248489 0.5550005325391472 0.6678109660783018 0.997034664784726 +20 ENSG0000010001 Tgd 107352 C T chr20:107352:C:T -489215 0.44531955311225835 0.8923679916355531 0.366385284168637 0.14467302290168813 +20 ENSG0000010001 Tgd 101108 T C chr20:101108:T:C -281639 0.726629134628846 0.9668951326671753 -0.1982265341894629 0.4181513880412051 +20 ENSG0000010001 Tgd 102267 C T chr20:102267:C:T -271528 0.893116485543652 0.4312373751553562 0.00789940112673615 0.47570830052922725 +20 ENSG0000010001 Tgd 100854 G A chr20:100854:G:A 336062 0.26324624208370195 0.9185225437292942 0.046631097698929036 0.39399094260283146 +20 ENSG0000010001 Tgd 103830 T A chr20:103830:T:A 227629 0.3346088959289498 0.37051631344423275 -0.5293659231110179 0.0070204080678989665 +20 ENSG0000010001 Tgd 100417 T G chr20:100417:T:G -290270 0.5777105049648884 0.7422037056372165 0.9139861897350174 0.3280445129691437 +20 ENSG0000010001 Tgd 107363 G C chr20:107363:G:C 314231 0.008834565537203853 0.19185205311932751 0.31247524526516557 0.3223473612448751 +20 ENSG0000010001 Tgd 107377 A G chr20:107377:A:G 24488 0.595378755642741 0.4633733965442437 0.4213598868101973 0.3449176470297304 +20 ENSG0000010001 Tgd 102602 G A chr20:102602:G:A 115195 0.7044637043971942 0.027621248671710896 0.662347134668474 0.5274417731196605 +20 ENSG0000010001 Tgd 102412 T G chr20:102412:T:G -279739 0.8603133887234419 0.7495791750944655 -0.7395241639697305 0.7289140758219048 +20 ENSG0000010001 Tgd 102954 A T chr20:102954:A:T -316037 0.9436929422875117 0.1472250408094028 -0.7934251113769883 0.7618151508639472 +20 ENSG0000010001 Tgd 107616 C G chr20:107616:C:G -53384 0.6067472854308188 0.9687120057032987 -0.7867840912500861 0.16521729417256226 +20 ENSG0000010001 Tgd 104826 T C chr20:104826:T:C -380442 0.2889501174405579 0.8371497135794698 -0.19170337055438047 0.5539055016372819 +20 ENSG0000010001 Tgd 100531 C T chr20:100531:C:T 485658 0.10356535640020437 0.4248312335860275 0.15716968488490024 0.20812301266886005 +20 ENSG0000010001 Tgd 102953 G A chr20:102953:G:A -399699 0.9968839286215477 0.890483440951564 -0.6312305528132878 0.39812315013534555 +20 ENSG0000010001 Tgd 108118 G A chr20:108118:G:A 410532 0.07145285942090263 0.4645531168843662 0.7741183304708183 0.02030747867874471 +20 ENSG0000010001 Tgd 103540 A G chr20:103540:A:G 468727 0.1940181437555567 0.8870939521382181 -0.9213246719811521 0.34309092749331616 +20 ENSG0000010001 Tgd 100177 A C chr20:100177:A:C 111637 0.19828450835256706 0.1847496510540606 0.6702614643996656 0.18435626987778672 +20 ENSG0000010001 Tgd 104582 G T chr20:104582:G:T 394237 0.11313246088493978 0.808339912001562 -0.6801806306361942 0.2793584203551503 +20 ENSG0000010001 Tgd 107268 G T chr20:107268:G:T 460369 0.5552070215741498 0.5399312393538087 0.9158054376068956 0.033478802999045716 +20 ENSG0000010001 Tgd 106516 A T chr20:106516:A:T 423770 0.3497940496786104 0.728527580296607 0.6352473197376829 0.5504916511977086 +20 ENSG0000010001 Tgd 101782 T G chr20:101782:T:G 234752 0.1580036803432291 0.758110631207051 -0.6396352717143576 0.8613178083890648 +20 ENSG0000010001 Tgd 102623 A G chr20:102623:A:G -266998 0.34806167820257994 0.04775800033260236 0.9498804177702083 0.5636490320957234 +20 ENSG0000010001 Tgd 107033 A T chr20:107033:A:T 370784 0.4304470845947138 0.4197813008171506 -0.20973429611501615 0.3317965592908765 +20 ENSG0000010001 Tgd 102813 G T chr20:102813:G:T 79825 0.6445212759354889 0.3558977170082218 -0.5891820253713116 0.4897627212443218 +20 ENSG0000010001 Tgd 109608 C A chr20:109608:C:A -25369 0.7227859571618627 0.5056654949423854 0.09226315371467253 0.30205127357876643 +20 ENSG0000010001 Tgd 100046 C G chr20:100046:C:G 387606 0.87103732691482 0.16964615914668768 0.09128057971938786 0.6654422301586981 +20 ENSG0000010001 Tgd 101693 T A chr20:101693:T:A -326038 0.1861707700166645 0.07775432545034844 -0.25719271933094423 0.8254542985748646 +20 ENSG0000010001 Tgd 104904 T A chr20:104904:T:A -206931 0.25904806362251853 0.5724223175188135 -0.9308104278924827 0.22594538346811657 +20 ENSG0000010001 Tgd 102571 C T chr20:102571:C:T -240723 0.2062899706759539 0.006560541372034545 -0.6644545757073386 0.35816336538023064 +20 ENSG0000010001 Tgd 100668 T C chr20:100668:T:C 449871 0.6519760251444626 0.3313847507838342 0.707014023861668 0.06032019146091175 +20 ENSG0000010001 Tgd 103707 C A chr20:103707:C:A -262984 0.8553161949278423 0.5808952637336674 0.6263187610266208 0.8087275282643874 +20 ENSG0000010001 Tgd 104667 T C chr20:104667:T:C 391081 0.24628977771188498 0.9191364211083306 0.1841909948997904 0.13313043666061172 +20 ENSG0000010001 Tgd 108805 A C chr20:108805:A:C 91743 0.7466210703582981 0.5383658185587914 0.2902189527525221 0.12332639879136731 +20 ENSG0000010001 Tgd 104415 C A chr20:104415:C:A -330454 0.8797038240714932 0.05753220948823545 0.5601514925560318 0.7516054877478316 +20 ENSG0000010001 Tgd 106436 C T chr20:106436:C:T 497593 0.056441829486969075 0.14264293940906858 0.9339617117704893 0.40208701082981996 +20 ENSG0000010001 Tgd 101233 C T chr20:101233:C:T -431249 0.906414441875275 0.3839307813514198 0.19059511683693464 0.8670972587759308 +20 ENSG0000010001 Tgd 101523 T G chr20:101523:T:G -141495 0.6221341191678023 0.7968298576607473 0.17191371519027765 0.18163065626567365 +20 ENSG0000010001 Tgd 107313 A T chr20:107313:A:T -395274 0.4816175801484066 0.2321191334914201 -0.1984354536517139 0.9442099625701356 +20 ENSG0000010001 Tgd 104491 G C chr20:104491:G:C -341514 0.6677797947305965 0.5086959423836716 0.8356190830266745 0.2526226422616246 +20 ENSG0000010001 Tgd 101686 T A chr20:101686:T:A 433606 0.6208108322748798 0.12046552783674647 0.6173030997284135 0.22934005999880466 +20 ENSG0000010001 Tgd 100074 T C chr20:100074:T:C -169274 0.8745599250303847 0.2704821159026356 -0.6178962712553839 0.7054453874438168 +20 ENSG0000010001 Tgd 101029 C T chr20:101029:C:T 401838 0.3318648960785995 0.009933094067834713 -0.8118257035180065 0.21067384876367104 +20 ENSG0000010001 Tgd 102287 C T chr20:102287:C:T 198551 0.8413162160617811 0.517424723888579 -0.1167668031884066 0.9174080713740618 +20 ENSG0000010001 Tgd 107553 T C chr20:107553:T:C -11220 0.6054646296339091 0.12684980313749405 0.38484827788545184 0.2520729557730971 +20 ENSG0000010001 Tgd 102152 T A chr20:102152:T:A 26089 0.5452561917622908 0.7081959830123075 -0.49125531869705696 0.7980971168557588 +20 ENSG0000010001 Tgd 105265 A T chr20:105265:A:T 271703 0.9276709330761966 0.007423656452529959 0.5433215430785945 0.4836194164912815 +20 ENSG0000010001 Tgd 100680 G T chr20:100680:G:T -280880 0.8806276115363698 0.7575536904495621 0.17782341822337755 0.9861911595212804 +20 ENSG0000010001 Tgd 107046 C A chr20:107046:C:A -124643 0.8726070792787612 0.9427560274091348 -0.6681416878060504 0.4678026775546016 +20 ENSG0000010001 Tgd 108895 C G chr20:108895:C:G -211708 0.0573300561563701 0.5197653273757065 0.273079626313689 0.7858245350688962 +20 ENSG0000010001 Tgd 105887 C G chr20:105887:C:G 245119 0.7937347104983474 0.13497568223275824 0.5770722206220191 0.018971472702297605 +20 ENSG0000010001 Tgd 108322 C G chr20:108322:C:G 5681 0.12532929076598687 0.5845010636666316 -0.6634364968178781 0.305838420808716 +20 ENSG0000010001 Tgd 103551 A G chr20:103551:A:G -323029 0.555449144236922 0.17261351036702766 0.7391527645343998 0.009614222826264781 +20 ENSG0000010001 Tgd 101742 T C chr20:101742:T:C 264764 0.7958144147968905 0.9338262128504331 -0.1885299955606068 0.7571760251301531 +20 ENSG0000010001 Tgd 104914 G T chr20:104914:G:T 79307 0.4111891551964204 0.5889823865926194 -0.4960959273455756 0.18109982154125687 +20 ENSG0000010001 Tgd 100209 A T chr20:100209:A:T 331435 0.16252524588766593 0.9220581224078459 -0.8256209747869745 0.5701618732498904 +20 ENSG0000010001 Tgd 102868 T G chr20:102868:T:G -458312 0.13437887586585684 0.3985019177216792 -0.47544759633301537 0.8312131074217204 +20 ENSG0000010001 Tgd 105615 A C chr20:105615:A:C -48789 0.19420530784958256 0.06675330905030696 0.6719077420985746 0.6473688912562935 +20 ENSG0000010001 Tgd 100308 T A chr20:100308:T:A -447674 0.7373238337059185 0.08440219294220819 -0.5607879572270764 0.37136480368116875 +20 ENSG0000010001 Tgd 103290 T C chr20:103290:T:C 376980 0.46368035743866964 0.08684349767593813 0.18377247783828943 0.3829391766885354 +20 ENSG0000010001 Tgd 100095 A G chr20:100095:A:G -477700 0.9317642340725407 0.1435661648318438 -0.028292929245891774 0.03823459523208754 +20 ENSG0000010001 Tgd 106554 C G chr20:106554:C:G -383716 0.923468878009076 0.748362298443804 0.6619069105467636 0.05583800823634576 +20 ENSG0000010001 Tgd 107143 T G chr20:107143:T:G -204952 0.2183886372202004 0.525721577653499 0.8787858985958781 0.011313044754494964 +20 ENSG0000010001 Tgd 109379 C T chr20:109379:C:T -14480 0.1734641507259398 0.27137690353139676 -0.8197365634934175 0.826336193972715 +20 ENSG0000010001 Tgd 102403 T A chr20:102403:T:A -284428 0.9830387895356616 0.8860590547191156 0.5730014206523686 0.11555152762247899 +20 ENSG0000010001 Tgd 104244 C A chr20:104244:C:A -43584 0.2996702800483769 0.938691237569225 0.4308323725930121 0.3897003187285146 +20 ENSG0000010001 Tgd 104523 C A chr20:104523:C:A 459859 0.7488657995807185 0.4597666947445058 -0.07215597525435169 0.6588338633989164 +20 ENSG0000010001 Tgd 106363 C G chr20:106363:C:G 497218 0.4202232650987475 0.9185864161852886 -0.9367078479827966 0.8587944057423917 +20 ENSG0000010001 Tgd 103415 T A chr20:103415:T:A 358562 0.27744320690631497 0.4285668790999948 -0.8610771227869174 0.32846600448704993 +20 ENSG0000010001 Tgd 105574 A G chr20:105574:A:G -479267 0.9980054057131905 0.8358934435712613 -0.01117148071940921 0.6158802870442517 +20 ENSG0000010001 Tgd 103094 T C chr20:103094:T:C 231206 0.1827521178213981 0.8822048095516867 -0.4259377336448147 0.21997348688431845 +20 ENSG0000010001 Tgd 105041 A G chr20:105041:A:G -323611 0.21902429512641008 0.3453504549592781 0.5618095894938873 0.7963344386829007 +20 ENSG0000010001 Tgd 108209 G C chr20:108209:G:C -29572 0.5702726078097186 0.9974332303611954 -0.6689844077984184 0.8742723246524369 +20 ENSG0000010001 Tgd 108783 C T chr20:108783:C:T -103114 0.8420666959961142 0.13681547655181292 0.11882381987303448 0.0424209759726606 +20 ENSG0000010001 Tgd 107662 G C chr20:107662:G:C -433710 0.6528369561738366 0.9792528521811841 -0.9935741931852682 0.3395646444775862 +20 ENSG0000010001 Tgd 108207 G C chr20:108207:G:C -317149 0.0913702502162369 0.7261130010971958 -0.5310883325146574 0.780449641029361 +20 ENSG0000010001 Tgd 109887 T G chr20:109887:T:G 59552 0.07765257553644656 0.6719616236339587 -0.9001781000983016 0.48924002432512886 +20 ENSG0000010001 Tgd 106727 A C chr20:106727:A:C -267081 0.45561069626501816 0.956185049612293 0.04510057362800879 0.2765315599893509 +20 ENSG0000010001 Tgd 107489 A G chr20:107489:A:G 263092 0.3751764825161873 0.5422322061094778 -0.09725547070441642 0.6521733715687381 +20 ENSG0000010001 Tgd 105758 G C chr20:105758:G:C 439626 0.41409384346812705 0.46735382923017144 0.3588731866603956 0.38831174630122883 +20 ENSG0000010001 Tgd 103832 G A chr20:103832:G:A -114394 0.6591215677330987 0.8822680465430529 -0.8257441592295884 0.37339424046620684 +20 ENSG0000010001 Tgd 108480 T G chr20:108480:T:G -1531 0.9245028100593236 0.16693716180968776 0.6862465904652557 0.012081881100638833 +20 ENSG0000010001 Tgd 108471 A G chr20:108471:A:G 181377 0.841257645470112 0.5620994373042788 -0.9591322647026788 0.9763167063590266 +20 ENSG0000010001 Tgd 105953 A C chr20:105953:A:C 443115 0.03650497814933662 0.7058878931997615 -0.11158594091223106 0.9149319938449634 +20 ENSG0000010001 Tgd 109702 A G chr20:109702:A:G 6511 0.6446121144297093 0.6658719048722859 -0.9554936615016556 0.405146965485306 +20 ENSG0000010001 Tgd 101971 T G chr20:101971:T:G -69757 0.8878525633932774 0.47537489169258285 0.14927213851173327 0.28192807907108525 +20 ENSG0000010001 Tgd 101332 A G chr20:101332:A:G 32765 0.6470427252878748 0.43090790755373853 -0.5639400258305467 0.7601675787133044 +20 ENSG0000010001 Tgd 109795 A G chr20:109795:A:G -6406 0.7514298722538814 0.5726411299013349 -0.5912993355888141 0.6800575758769607 +20 ENSG0000010001 Tgd 102772 A C chr20:102772:A:C 337623 0.9942568737095628 0.32265284544349104 -0.9561854028129206 0.6710749298644351 +20 ENSG0000010001 Tgd 104960 A G chr20:104960:A:G -438467 0.26236174738341334 0.8564475965576949 -0.1548251097650195 0.7004586366569808 +20 ENSG0000010001 Tgd 101274 A G chr20:101274:A:G -90265 0.2059327452392803 0.8389358972101826 0.5250732015032789 0.4028169255796299 +20 ENSG0000010001 Tgd 102669 A G chr20:102669:A:G -299033 0.9435053826092519 0.580216598371821 -0.6453772967049825 0.837140917520681 +20 ENSG0000010001 Tgd 101313 T G chr20:101313:T:G -374173 0.5618522849225882 0.4186795629741842 -0.35428367606139943 0.8836857068292419 +20 ENSG0000010001 Tgd 103344 T G chr20:103344:T:G -405170 0.45754114342881536 0.9144201272879167 -0.9878483931140087 0.4234657540733826 +20 ENSG0000010001 Tgd 105046 C T chr20:105046:C:T -75091 0.5873122684056813 0.1577350723013805 -0.5875063282554851 0.695760583801322 +20 ENSG0000010001 Tgd 108775 T A chr20:108775:T:A 207339 0.7710827159688273 0.9576412761720637 -0.395026211632969 0.9895775312192285 +20 ENSG0000010001 Tgd 109856 A G chr20:109856:A:G 127902 0.17963222461573325 0.6169302265344454 0.6390520563514266 0.43975001529351665 +20 ENSG0000010001 Tgd 100033 T C chr20:100033:T:C -256731 0.5614111864005236 0.5126296858675714 0.5515475463559636 0.6590302644637476 +20 ENSG0000010001 Tgd 104020 A T chr20:104020:A:T 320835 0.8715652651618259 0.6782945381255897 0.4807617526552779 0.46644250515069435 +20 ENSG0000010001 Tgd 108828 A G chr20:108828:A:G -5622 0.5019979391994505 0.9274230227290122 -0.227270742743944 0.3775282601035707 +20 ENSG0000010001 Tgd 104442 T A chr20:104442:T:A -139563 0.8830281916648137 0.5277039377383765 0.7273948901236837 0.7588648491504002 +20 ENSG0000010001 Tgd 104139 T A chr20:104139:T:A -155472 0.001472698149928009 0.9394823867735884 0.5494213409182629 0.11532320561616143 +20 ENSG0000010001 Tgd 100892 T G chr20:100892:T:G 161453 0.2983438077757603 0.4462665384995602 -0.9041518091620939 0.032056739208581236 +20 ENSG0000010001 Tgd 108838 G T chr20:108838:G:T -78356 0.15022264069834446 0.16560440212963723 0.8917383613380654 0.550717519295807 +20 ENSG0000010001 Tgd 104850 G T chr20:104850:G:T 41421 0.5076423560065856 0.5794536245311858 -0.3222418732731125 0.5653819517989968 +20 ENSG0000010001 Tgd 107651 C A chr20:107651:C:A -421083 0.41894837126014306 0.0021822335048193864 0.8741184412291096 0.6857375422658096 +20 ENSG0000010001 Tgd 109828 G A chr20:109828:G:A -320180 0.7998090794104923 0.4061445101493084 -0.7351365981168154 0.5579118393142559 +20 ENSG0000010001 Tgd 108690 T A chr20:108690:T:A -248229 0.6249004387859023 0.45628947806968223 0.27120525773480475 0.8046601972286032 +20 ENSG0000010001 Tgd 106903 T C chr20:106903:T:C -205759 0.2693234996374102 0.3260635718931899 0.18972422751017182 0.6305838560932112 +20 ENSG0000010001 Tgd 103013 G A chr20:103013:G:A -414832 0.1786427051644922 0.7357847001133759 -0.4095298080070846 0.6622620204874572 +20 ENSG0000010001 Tgd 102337 C T chr20:102337:C:T 189574 0.8769052801574393 0.21494962578879184 0.1933415087844037 0.585981312110534 +20 ENSG0000010001 Tgd 102560 T G chr20:102560:T:G -118076 0.24864401674982106 0.18263961040466792 0.818945367131533 0.5703063360519545 +20 ENSG0000010001 Tgd 106637 A T chr20:106637:A:T 139678 0.3767225269155591 0.761045064396108 -0.9984616766592986 0.9183725161586713 +20 ENSG0000010001 Tgd 104812 T G chr20:104812:T:G -166296 0.13295761379943527 0.7648551157966053 0.37941158277301024 0.042986609724004886 +20 ENSG0000010001 Tgd 105815 T G chr20:105815:T:G -231731 0.5012321602843645 0.07915919050508968 0.0655769380204756 0.44017581145452755 +20 ENSG0000010001 Tgd 106017 C A chr20:106017:C:A -245121 0.8737039595850393 0.8270690493411301 -0.4560454660594442 0.877303916014452 +20 ENSG0000010001 Tgd 108357 T A chr20:108357:T:A -130610 0.8742783048514248 0.5699555535001265 0.9961551651122118 0.24952091235110896 +20 ENSG0000010001 Tgd 106053 C G chr20:106053:C:G -68916 0.152270160608461 0.1975855153853462 -0.7456537599739272 0.42845964189173225 +20 ENSG0000010001 Tgd 106245 G C chr20:106245:G:C 113739 0.07369015462210593 0.37283321158198135 -0.37917611648220406 0.8167800044426118 +20 ENSG0000010001 Tgd 102854 T A chr20:102854:T:A 497526 0.25657229264076986 0.6048321986528847 -0.22609682106198536 0.1666197801179048 +20 ENSG0000010001 Tgd 106730 T A chr20:106730:T:A -97524 0.4169528812032576 0.07267145787550788 -0.09259019868630602 0.9314848015355076 +20 ENSG0000010001 Tgd 109559 G T chr20:109559:G:T -301669 0.8925403233226584 0.37695534236932404 0.9705334542692978 0.9087724573895174 +20 ENSG0000010001 Tgd 109844 T C chr20:109844:T:C 288000 0.5528460274249601 0.47745924342543855 0.9450750261517948 0.5564219143484019 +20 ENSG0000010001 Tgd 107603 T C chr20:107603:T:C 460877 0.7809889572398986 0.0123573042534878 -0.7571639083764099 0.25555214020361505 +20 ENSG0000010001 Tgd 102829 A C chr20:102829:A:C 438698 0.6080087111376111 0.24701934379075197 -0.34525875448968923 0.6035194137644195 +20 ENSG0000010001 Tgd 103107 A T chr20:103107:A:T -367823 0.40245093412580735 0.029330961439155145 0.7936096350326913 0.29030327148134516 +20 ENSG0000010001 Tgd 100814 T A chr20:100814:T:A 330901 0.30495966778093 0.6520632554690166 -0.5463422707780143 0.03472195553663724 +20 ENSG0000010001 Tgd 104658 A T chr20:104658:A:T -184883 0.11820877355845771 0.20412524429400403 0.6230547960834469 0.49621043724623143 +20 ENSG0000010001 Tgd 102496 G T chr20:102496:G:T -465217 0.5914367259509679 0.5401461901871766 0.2888547528866676 0.8329904284677688 +20 ENSG0000010001 Tgd 106288 C T chr20:106288:C:T 278339 0.785904308163593 0.9398216508127358 -0.7291353598706207 0.9086821210261073 +20 ENSG0000010001 Tgd 105399 T A chr20:105399:T:A 43781 0.182651454460116 0.3368336173269959 -0.5357449944171275 0.570657476734784 +20 ENSG0000010001 Tgd 107938 A C chr20:107938:A:C 85838 0.9057440729472126 0.4006787696860905 0.8307473948254078 0.568816649319417 +20 ENSG0000010001 Tgd 108933 A C chr20:108933:A:C -78160 0.5339481095351918 0.8793467507087726 -0.8296498734674147 0.6592228746423933 +20 ENSG0000010001 Tgd 104031 A G chr20:104031:A:G 145594 0.4084911823946248 0.10050404024457404 0.05238454685529215 0.5722990769287372 +20 ENSG0000010001 Tgd 107870 T C chr20:107870:T:C 390843 0.8466252089047995 0.30962009167603255 0.5908053806331233 0.3080462657977772 +20 ENSG0000010001 Tgd 104221 A T chr20:104221:A:T -166566 0.22553832057390466 0.0725426052261029 -0.6116576718961915 0.6608156765852431 +20 ENSG0000010001 Tgd 105174 G A chr20:105174:G:A -486649 0.05182980370671031 0.49019198489090854 -0.6071014159565631 0.17038870659620545 +20 ENSG0000010001 Tgd 108132 C A chr20:108132:C:A -263278 0.41904371295989296 0.7575693322390223 0.5235903063899412 0.1801593025701655 +20 ENSG0000010001 Tgd 100738 T C chr20:100738:T:C 373805 0.6220137383357498 0.8358251048909772 0.1952404636477454 0.07191167166974773 +20 ENSG0000010001 Tgd 103249 G T chr20:103249:G:T -279834 0.4596218469762413 0.18987730367682853 0.4635248062588049 0.8105547104971802 +20 ENSG0000010001 Tgd 105088 C G chr20:105088:C:G -199467 0.5499501795242259 8.542671599032214e-05 -0.45813278118696377 0.4318206615868734 +20 ENSG0000010001 Tgd 107274 G T chr20:107274:G:T 312087 0.2254926585794481 0.9864450772530504 0.8460099692446086 0.8849701323146606 +20 ENSG0000010001 Tgd 107708 G C chr20:107708:G:C -420082 0.7773921620626418 0.6083008130736085 0.5728551964643149 0.6302450625530027 +20 ENSG0000010001 Tgd 109132 C A chr20:109132:C:A 6799 0.6950765195406398 0.9610136125788833 -0.6670825948733392 0.5386746869124204 +20 ENSG0000010001 Tgd 105688 A C chr20:105688:A:C -131242 0.38352666193683194 0.9716005344375462 -0.9259211926904538 0.8141291082970886 +20 ENSG0000010001 Tgd 109148 C A chr20:109148:C:A -138962 0.3463167290732937 0.7419876164127418 0.4578395148606016 0.807952739628708 +20 ENSG0000010001 Tgd 105259 G C chr20:105259:G:C -215576 0.7183132305798433 0.619154553058748 0.33815377005555347 0.24962748371567622 +20 ENSG0000010001 Tgd 101917 G A chr20:101917:G:A 178022 0.49189693347557006 0.47279488297323014 -0.8988431500635081 0.012296606549951176 +20 ENSG0000010001 Tgd 104028 A C chr20:104028:A:C -165575 0.8927884497624504 0.1172296668557542 -0.4474171402348275 0.019356611918408827 +20 ENSG0000010001 Tgd 104074 T G chr20:104074:T:G -87222 0.7689454418444531 0.7671801741404208 0.47683123843945485 0.0408656740956668 +20 ENSG0000010001 Tgd 108418 C G chr20:108418:C:G 217742 0.9485196491979151 0.6283420322246988 0.386746328230845 0.022020714069987766 +20 ENSG0000010001 Tgd 107288 A T chr20:107288:A:T -89229 0.32169594733005635 0.6080804966227301 -0.32410772009874855 0.9708553146600292 +20 ENSG0000010001 Tgd 106261 C G chr20:106261:C:G 243748 0.6003131509322419 0.8669516384879028 0.4447498207797107 0.3432032520332346 +20 ENSG0000010001 Tgd 106841 A T chr20:106841:A:T 134285 0.9854536314936186 0.2999810521576337 0.7000084075430784 0.503634413011187 +20 ENSG0000010001 Tgd 108311 A G chr20:108311:A:G 11057 0.04257149626008505 0.7198342529308389 0.21023822662814173 0.48348496006733027 +20 ENSG0000010001 Tgd 100698 T A chr20:100698:T:A 212506 0.7156387203744387 0.5994852013833188 0.2302673025825086 0.5413105392624182 +20 ENSG0000010001 Tgd 104623 T A chr20:104623:T:A -403662 0.19969215751252656 0.8561588593607287 -0.7094811229295006 0.39040782567257987 +20 ENSG0000010001 Tgd 101643 A C chr20:101643:A:C 63204 0.27567705179411783 0.33850335747657123 -0.9059086092872886 0.16384636447237538 +20 ENSG0000010001 Tgd 106543 G A chr20:106543:G:A -190389 0.9941949952753024 0.7987203872482789 0.34447151404304077 0.15977328534121296 +20 ENSG0000010001 Tgd 100297 C T chr20:100297:C:T 129795 0.9049838294862489 0.6781205535457314 -0.04790241304923537 0.9520209904936268 +20 ENSG0000010001 Tgd 105954 G A chr20:105954:G:A 405490 0.5318225821770436 0.8917124918022125 0.5451511612174902 0.9186153399864723 +20 ENSG0000010001 Tgd 103223 A G chr20:103223:A:G 287181 0.06352342880722472 0.3904015104912061 -0.8531425174642464 0.6179690080189901 +20 ENSG0000010001 Tgd 105554 T C chr20:105554:T:C -58315 0.8763992249419701 0.48591758164693777 -0.22502812746461975 0.40876588720931295 +20 ENSG0000010001 Tgd 106676 C G chr20:106676:C:G 467677 0.0027760294325804846 0.232089154245131 -0.9727811345775741 0.7492912607266228 +20 ENSG0000010001 Tgd 101208 C A chr20:101208:C:A -363958 0.3739702961307898 0.8129545193577111 0.8144319273296647 0.0069317222004065746 +20 ENSG0000010001 Tgd 106362 G A chr20:106362:G:A -153295 0.9281263560995525 0.05183378155060647 -0.5269919329653687 0.39683039848814855 +20 ENSG0000010001 Tgd 103911 G A chr20:103911:G:A -111016 0.04401679433335137 0.7309340352632241 0.7741988545815801 0.08864229507991946 +20 ENSG0000010001 Tgd 107028 C A chr20:107028:C:A 154148 0.5450186624211695 0.12068302937559028 0.719162214046055 0.587055020486995 +20 ENSG0000010001 Tgd 109706 A T chr20:109706:A:T -438447 0.8054940904735023 0.23725759714167216 -0.9423750170594098 0.3654716189438131 +20 ENSG0000010001 Tgd 100382 G C chr20:100382:G:C 96035 0.4674909017690554 0.5974558097620911 -0.5374695679922683 0.11300179085808704 +20 ENSG0000010001 Tgd 103059 G A chr20:103059:G:A -448055 0.6232809850320803 0.5334461586950943 -0.9140041599713573 0.8631771832484086 +20 ENSG0000010001 Tgd 107594 C G chr20:107594:C:G 479836 0.29527576015581347 0.32168072654150104 0.6226405095063794 0.9815009609947676 +20 ENSG0000010001 Tgd 109676 T A chr20:109676:T:A -165481 0.28582998176788244 0.5568368506628595 0.20994979562634053 0.6937923053356109 +20 ENSG0000010001 Tgd 105397 T A chr20:105397:T:A -369604 0.557437941553369 0.6306217056591794 -0.758448768878486 0.5484759866121987 +20 ENSG0000010001 Tgd 106379 T C chr20:106379:T:C 429368 0.8389676499759274 0.2829901334799011 -0.33965739014540763 0.9803705562855175 +20 ENSG0000010001 Tgd 102448 A G chr20:102448:A:G 146479 0.4950415644968519 0.3148973263756286 -0.18519755631854884 0.013059539634726919 +20 ENSG0000010001 Tgd 106692 A G chr20:106692:A:G 381177 0.13953976563809 0.5417607681681006 -0.9390332781129338 0.01147451811310913 +20 ENSG0000010001 Tgd 107355 T G chr20:107355:T:G 445603 0.9215055734374004 0.016035431109978404 -0.6065193362039409 0.7999772166558422 +20 ENSG0000010001 Tgd 101031 C T chr20:101031:C:T 213970 0.004368030040350135 0.4412190782308538 0.35878148266428256 0.6351735751344008 +20 ENSG0000010001 Tgd 101478 A C chr20:101478:A:C -56194 0.053968588611937984 0.526559303999228 0.14416322204229792 0.3740462609814077 +20 ENSG0000010001 Tgd 102937 A T chr20:102937:A:T -242790 0.5907306173920427 0.3075907412345531 0.13433525361639687 0.057557789839398306 +20 ENSG0000010001 Tgd 106151 T A chr20:106151:T:A 213041 0.8116504871835855 0.6943966071230849 0.9750279473945631 0.4680707111205243 +20 ENSG0000010001 Tgd 100892 C G chr20:100892:C:G -370912 0.57266951302868 0.7353397166725391 0.5169425404516723 0.9324734796076127 +20 ENSG0000010001 Tgd 109431 C G chr20:109431:C:G 108946 0.21480807982150607 0.33009772292035255 0.7703494149901768 0.554175248129788 +20 ENSG0000010001 Tgd 103192 C G chr20:103192:C:G -223341 0.627201271582787 0.5595661659539197 -0.20802385290058534 0.9548907319524039 +20 ENSG0000010001 Tgd 103044 T G chr20:103044:T:G 388736 0.4740478009081547 0.7310365668587548 0.08412176766036761 0.2451162938153978 +20 ENSG0000010001 Tgd 100098 A T chr20:100098:A:T -328094 0.025533434774502983 0.35988070392971216 -0.02226218220747267 0.21779686069834275 +20 ENSG0000010001 Tgd 102354 G T chr20:102354:G:T 324321 0.6826123530660675 0.2103333068305433 0.9965829828472581 0.4054676365018392 +20 ENSG0000010001 Tgd 104245 A T chr20:104245:A:T 410769 0.5606710159894778 0.13337140025317673 -0.5198538636701322 0.16470175141589097 +20 ENSG0000010001 Tgd 106469 T C chr20:106469:T:C -326631 0.4392960553869437 0.9184461849686286 0.24389892716783335 0.7093995060048565 +20 ENSG0000010001 Tgd 103668 C T chr20:103668:C:T -450996 0.13666068195028946 0.6860105185386605 -0.9566178236122185 0.09482681119524548 +20 ENSG0000010001 Tgd 100003 A G chr20:100003:A:G 146811 0.18889887055719778 0.7611453816173691 -0.6496256363948332 0.2796213973838221 +20 ENSG0000010001 Tgd 102266 T C chr20:102266:T:C 18671 0.6598429089084424 0.6046499579473558 0.050542476018530014 0.8895685322992488 +20 ENSG0000010001 Tgd 100149 G C chr20:100149:G:C 359704 0.3210821215958721 0.08410370594453564 0.6854822526682764 0.6903535127025426 +20 ENSG0000010001 Tgd 102079 G A chr20:102079:G:A 459277 0.925980891604465 0.323607455465328 0.1367880208749499 0.609742466611515 +20 ENSG0000010001 Tgd 101138 A G chr20:101138:A:G 326909 0.2843460066965321 0.24585489342692557 0.3468692623782972 0.1851207501864683 +20 ENSG0000010001 Tgd 107087 A G chr20:107087:A:G 429775 0.7259765677618386 0.6998434287316387 -0.9324601746359227 0.3990273351178115 +20 ENSG0000010001 Tgd 104895 G A chr20:104895:G:A 470470 0.8026550072651344 0.003449009413535653 0.11702338399747347 0.05330758789779361 +20 ENSG0000010001 Tgd 106201 A C chr20:106201:A:C 144205 0.3131919366826542 0.6239049323158216 0.592297767165832 0.1361367736126804 +20 ENSG0000010001 Tgd 104714 G C chr20:104714:G:C 263284 0.053645745905313014 0.8978068567518814 -0.4595027265175786 0.6757221077185552 +20 ENSG0000010001 Tgd 107117 G C chr20:107117:G:C 30935 0.16700447669645868 0.45344310566967716 -0.7245597933046481 0.5696054795762727 +20 ENSG0000010001 Tgd 100040 G T chr20:100040:G:T -485537 0.8427696305514113 0.24511026372453937 -0.19032406522467338 0.8050454040158412 +20 ENSG0000010001 Tgd 105847 G C chr20:105847:G:C 491810 0.4116230437824764 0.07097377093676105 0.14735319387639545 0.2679985257666276 +20 ENSG0000010001 Tgd 109749 G T chr20:109749:G:T -390438 0.5227186227240525 0.21758934096202387 0.1741491809335769 0.7703045802426499 +20 ENSG0000010001 Tgd 107937 C A chr20:107937:C:A -229796 0.598742096974662 0.7060657032287575 -0.1455013448837148 0.5896880329128558 +20 ENSG0000010001 Tgd 105161 C A chr20:105161:C:A 408879 0.2820956453473522 0.7022002548011816 0.32367769192959583 0.14377952981533487 +20 ENSG0000010001 Tgd 106832 G C chr20:106832:G:C -273007 0.12755898484429762 0.7453015612246969 0.9507193355333448 0.2580026520810656 +20 ENSG0000010001 Tgd 106243 A T chr20:106243:A:T -394258 0.15694847493321473 0.5480526505837129 0.4077775170588547 0.8806395743424726 +20 ENSG0000010001 Tgd 101223 A C chr20:101223:A:C 145836 0.288316641467697 0.9327856253045368 -0.544043134875926 0.01726735516696933 +20 ENSG0000010001 Tgd 101200 T G chr20:101200:T:G -41838 0.7413125090227409 0.9877102443516721 0.7513553524516381 0.13833319870166066 +20 ENSG0000010001 Tgd 103164 C G chr20:103164:C:G -185248 0.1726249965035236 0.889503709443986 0.2739498788359076 0.341666942933902 +20 ENSG0000010001 Tgd 107555 G A chr20:107555:G:A 388400 0.5133918208953085 0.5011869708177111 -0.7173123671264436 0.9652258017259768 +20 ENSG0000010001 Tgd 103360 A C chr20:103360:A:C 189191 0.5466555429438584 0.84782006807717 -0.8652149232039923 0.5226343878539385 +20 ENSG0000010001 Tgd 106299 A T chr20:106299:A:T 231809 0.7233366463737028 0.5755345496716634 -0.2598442375538641 0.30664139716380157 +20 ENSG0000010001 Tgd 109421 C G chr20:109421:C:G -474309 0.7530383443791281 0.3245672919997118 -0.143237312336288 0.4443789606236562 +20 ENSG0000010001 Tgd 104413 G T chr20:104413:G:T 426515 0.6782707537828134 0.24144187548060125 -0.9925853929472561 0.6212745935039369 +20 ENSG0000010001 Tgd 107288 G A chr20:107288:G:A -446843 0.8394106964990738 0.059353974267319476 0.7601138970361481 0.41776365598730997 +20 ENSG0000010001 Tgd 106295 G T chr20:106295:G:T -492232 0.09895645393948749 0.3226515230262922 0.8017367321052535 0.7327224444238019 +20 ENSG0000010001 Tgd 108300 G C chr20:108300:G:C -153400 0.49926224101714556 0.9267890492285676 0.8940438687592329 0.3231512261066622 +20 ENSG0000010001 Tgd 105874 G C chr20:105874:G:C -395273 0.9911980477427147 0.17214789431367583 -0.05947942389617289 0.2753225708433624 +20 ENSG0000010001 Tgd 100113 A G chr20:100113:A:G 49217 0.44641082985385117 0.5210195167876518 0.618589958770944 0.8085482677029336 +20 ENSG0000010001 Tgd 102176 C A chr20:102176:C:A -125225 0.07129111449959258 0.3826145183511095 -0.4892920058206305 0.10740486656689893 +20 ENSG0000010001 Tgd 102870 C A chr20:102870:C:A 307235 0.5122921585196883 0.6116223444961714 0.8659067347065523 0.005933337417070298 +20 ENSG0000010001 Tgd 103305 T G chr20:103305:T:G 456457 0.5344106405832734 0.42580060673496545 0.025117379062347123 0.2341478218858011 +20 ENSG0000010001 Tgd 105215 G A chr20:105215:G:A 265659 0.06352296808835334 0.019879854905094807 -0.509699189540606 0.19479187899482459 +20 ENSG0000010001 Tgd 104888 C T chr20:104888:C:T 460817 0.21216076249401672 0.6429877535344082 -0.8784737263119449 0.04617693952855682 +20 ENSG0000010001 Tgd 105453 A T chr20:105453:A:T -468127 0.9831192687803009 0.7768590813327604 -0.444045964677519 0.07009396718724493 +20 ENSG0000010001 Tgd 104410 A G chr20:104410:A:G 168960 0.06621354686969882 0.6074020152958511 0.1927532923935491 0.8681385643988035 +20 ENSG0000010001 Tgd 109435 G T chr20:109435:G:T 381537 0.27273597819086426 0.9900326367680472 0.11047734720596902 0.11040636126350739 +20 ENSG0000010001 Tgd 105941 G C chr20:105941:G:C 52208 0.0131825156422265 0.3177731775818241 -0.91552528047504 0.20543931599396123 +20 ENSG0000010001 Tgd 106188 G C chr20:106188:G:C 34185 0.9736826865648458 0.014160726763582931 -0.35626385363541013 0.6405795925745302 +20 ENSG0000010001 Tgd 103650 C A chr20:103650:C:A 431419 0.33678237784264964 0.8283870266969301 0.5225367180780589 0.04611223150950264 +20 ENSG0000010001 Tgd 107082 A T chr20:107082:A:T 252067 0.6169912535769839 0.2702648501630043 0.3013472239958188 0.8089334521052005 +20 ENSG0000010001 Tgd 100726 T A chr20:100726:T:A -129041 0.9113475719872577 0.6004646120589763 0.5254126062976128 0.3327914206762904 +20 ENSG0000010001 Tgd 104594 A G chr20:104594:A:G -299502 0.8443840243829704 0.1535648557608501 -0.545284657234415 0.5639578544598645 +20 ENSG0000010001 Tgd 107210 C G chr20:107210:C:G -17366 0.3625741869931106 0.36529964920630675 0.8972381966364202 0.6566497171927527 +20 ENSG0000010001 Tgd 101093 G C chr20:101093:G:C 453211 0.6867358350953521 0.7216345232648171 -0.5970668196127782 0.5013593951199967 +20 ENSG0000010001 Tgd 102116 C G chr20:102116:C:G 230156 0.5143029526321656 0.9375597557161279 -0.7879576150990795 0.420864345423984 +20 ENSG0000010001 Tgd 104010 G A chr20:104010:G:A 272620 0.6428250324770398 0.7225715707885935 -0.24651225333762916 0.623087865754867 +20 ENSG0000010001 Tgd 104587 T G chr20:104587:T:G -59609 0.8386436438602622 0.29253555035659506 0.03270747080127845 0.09955832407964182 +20 ENSG0000010001 Tgd 107266 T A chr20:107266:T:A -97401 0.4028551219537354 0.8434243842240832 -0.5727271339714046 0.96663982161581 +20 ENSG0000010001 Tgd 101417 C A chr20:101417:C:A 351405 0.5296310627708057 0.8935225292908326 0.528712482606293 0.46927029773847373 +20 ENSG0000010001 Tgd 108203 T C chr20:108203:T:C 316777 0.14668141220773745 0.38148480522132433 -0.276372360859777 0.3405458524790651 +20 ENSG0000010001 Tgd 105119 G A chr20:105119:G:A 478913 0.42040847188123354 0.1527625488904607 -0.7329648813580245 0.7252077836563237 +20 ENSG0000010001 Tgd 103606 G A chr20:103606:G:A -27816 0.6246738024248697 0.9458398191576564 -0.9460502567783591 0.15235286980136897 +20 ENSG0000010001 Tgd 102806 T G chr20:102806:T:G 212307 0.8275245247275297 0.05661401924425036 0.41685886401759653 0.796779460200275 +20 ENSG0000010001 Tgd 107020 G A chr20:107020:G:A 203698 0.8885719891800673 0.2805679724359498 -0.06796909891917213 0.4471815294947031 +20 ENSG0000010001 Tgd 105292 C A chr20:105292:C:A 157582 0.7910616803554447 0.42071926963627015 -0.37207960614749 0.20332252137180468 +20 ENSG0000010001 Tgd 108599 G T chr20:108599:G:T -14752 0.5141883348398574 0.3527423633872384 -0.8703960728584887 0.4946183910438838 +20 ENSG0000010001 Tgd 100952 G T chr20:100952:G:T -75341 0.8267742287362224 0.21009788293784815 -0.47285091056683615 0.5122147084165407 +20 ENSG0000010001 Tgd 106735 T A chr20:106735:T:A 403080 0.15555459975812447 0.016894181707857836 -0.04202669264981629 0.08019428671737566 +20 ENSG0000010001 Tgd 103897 G A chr20:103897:G:A -310830 0.11451629501323535 0.6315966307100003 0.33580017987828303 0.028829451020082747 +20 ENSG0000010001 Tgd 105468 T G chr20:105468:T:G 388494 0.6556632651696949 0.762417943017866 0.021487113341928765 0.13468128580349578 +20 ENSG0000010001 Tgd 100436 G A chr20:100436:G:A 459875 0.4017899661363956 0.7152686250241481 0.6996194566149121 0.596394548331285 +20 ENSG0000010001 Tgd 101941 A G chr20:101941:A:G 114608 0.13195517077629315 0.48104763611656254 -0.7065308602231786 0.5552821078735184 +20 ENSG0000010001 Tgd 106351 C G chr20:106351:C:G 193478 0.3037881672939057 0.9021201465585933 0.8426404602262403 0.24336779731612104 +20 ENSG0000010001 Tgd 105181 A G chr20:105181:A:G 14672 0.3279036317783718 0.5110324890478211 -0.17246858980875923 0.5190458370384399 +20 ENSG0000010001 Tgd 103692 T C chr20:103692:T:C -128476 0.6905170041776527 0.013269706073150034 -0.026323222484302855 0.23688950555023053 +20 ENSG0000010001 Tgd 101664 A C chr20:101664:A:C -154736 0.3402636098275007 0.042708089063655974 0.6883153731768092 0.31897345016552736 +20 ENSG0000010001 Tgd 100537 C T chr20:100537:C:T 174976 0.09361415002344253 0.4784411461492427 0.20700820796939512 0.8772969257266189 +20 ENSG0000010001 Tgd 103648 C A chr20:103648:C:A -173705 0.3676444886763065 0.5091008285984018 -0.5815268441338746 0.9718867253756043 +20 ENSG0000010001 Tgd 105102 A C chr20:105102:A:C 430887 0.4833972748441534 0.05140626170784757 0.8394924506777628 0.10330032720260465 +20 ENSG0000010001 Tgd 102497 T C chr20:102497:T:C 392161 0.04921956508198455 0.4005963469725411 0.9809603459234473 0.11471700620632645 +20 ENSG0000010001 Tgd 106448 G A chr20:106448:G:A 416151 0.8824801455596359 0.23212076454467734 0.9470454648517541 0.8044922623723726 +20 ENSG0000010001 Tgd 104375 C G chr20:104375:C:G 37267 0.2919225265339358 0.4120137093687557 -0.053942567489967175 0.8103950479116366 +20 ENSG0000010001 Tgd 100406 T G chr20:100406:T:G 260877 0.8562247784977626 0.9537788428229327 0.628807053292527 0.06732726063262222 +20 ENSG0000010001 Tgd 103571 T C chr20:103571:T:C 3070 0.21862979053245857 0.49860912193381723 0.3238103420780989 0.8687354384802742 +20 ENSG0000010001 Tgd 105818 G C chr20:105818:G:C -24989 0.7064184763803817 0.16016696096524563 0.8200240836039305 0.6696906007986876 +20 ENSG0000010001 Tgd 107196 T A chr20:107196:T:A 33771 0.39350280882218414 0.5595602823348581 0.4860783697422937 0.710959696797342 +20 ENSG0000010001 Tgd 102240 A C chr20:102240:A:C 86374 0.36828876228456686 0.7052207712969839 -0.39140044685404063 0.16451373929481083 +20 ENSG0000010001 Tgd 103716 C A chr20:103716:C:A -105825 0.8545364364435167 0.7363880080941937 -0.8620548613370924 0.3476125168964413 +20 ENSG0000010001 Tgd 104167 T G chr20:104167:T:G 335816 0.38906118291591096 0.9467342232656759 0.8207640380755654 0.30059121784825105 +20 ENSG0000010001 Tgd 106297 G C chr20:106297:G:C -92339 0.1766859794196146 0.12233171869350157 0.48602093208118524 0.5727295951871562 +20 ENSG0000010001 Tgd 108926 C A chr20:108926:C:A 466344 0.6271115577746642 0.2677347715252911 0.8637825239203658 0.9291587195035039 +20 ENSG0000010001 Tgd 101883 G A chr20:101883:G:A -36579 0.002937386458144342 0.013127930077199479 -0.6768760696417118 0.16641923328374061 +20 ENSG0000010001 Tgd 108416 A G chr20:108416:A:G 91967 0.5518113976106441 0.6455304312268583 0.8855838520330079 0.8913490956532595 +20 ENSG0000010001 Tgd 101621 T C chr20:101621:T:C 378472 0.2734574129257077 0.47951271672996854 0.3981009556257604 0.059515050161839736 +20 ENSG0000010001 Tgd 109680 C T chr20:109680:C:T 227706 0.48685340442405123 0.4497484884247298 -0.9483390936859846 0.9962275919268505 +20 ENSG0000010001 Tgd 109691 T G chr20:109691:T:G -197365 0.6644379171499752 0.9969207066399158 0.9421868652296421 0.7708798847966161 +20 ENSG0000010001 Tgd 100470 T G chr20:100470:T:G 394164 0.6344148989608949 0.9692444200279082 0.49820257767394405 0.5755628328195437 +20 ENSG0000010001 Tgd 109587 G T chr20:109587:G:T -377763 0.5578302509389199 0.18860761385870062 -0.24577684026330893 0.4602200142069992 +20 ENSG0000010001 Tgd 109827 T C chr20:109827:T:C 282872 0.39415632125191835 0.24051030932281048 -0.6522078393204851 0.9501797584801737 +20 ENSG0000010001 Tgd 100526 C A chr20:100526:C:A -424115 0.8996443747622345 0.20875677261649084 -0.12456375402287745 0.4239533440781609 +20 ENSG0000010001 Tgd 103617 C A chr20:103617:C:A -401657 0.47435298460903974 0.45233949731490153 -0.8556663643211451 0.1505702159853953 +20 ENSG0000010001 Tgd 104988 C G chr20:104988:C:G -373859 0.274347814126057 0.026901778703789403 -0.6715908317075856 0.24606791973178974 +20 ENSG0000010001 Tgd 105742 A G chr20:105742:A:G -181186 0.8514661818403966 0.9079656553305424 -0.13143800375339265 0.3078627230448453 +20 ENSG0000010001 Tgd 106176 G T chr20:106176:G:T 13399 0.751607903303509 0.3796100483699536 -0.8670312528668098 0.5849719618448055 +20 ENSG0000010001 Tgd 105845 G C chr20:105845:G:C -126692 0.5826478358949244 0.1579507264447121 -0.6345845984523357 0.685623791338749 +20 ENSG0000010001 Tgd 106155 C A chr20:106155:C:A -186864 0.6078559536112934 0.026325808587162824 0.8545880743610113 0.9687774747909604 +20 ENSG0000010001 Tgd 108972 C A chr20:108972:C:A -312410 0.7429511010764659 0.33452255534585607 -0.872908238640318 0.7222843814625662 +20 ENSG0000010001 Tgd 103413 C G chr20:103413:C:G 4481 0.14068184182470989 0.5334450893894207 0.07188734752973636 0.5730902494027676 +20 ENSG0000010001 Tgd 104927 G T chr20:104927:G:T -255236 0.06610468218245302 0.9251514402121097 -0.44801334473534626 0.7314838576406104 +20 ENSG0000010001 Tgd 101372 C G chr20:101372:C:G -193386 0.5802596422244505 0.19797305128586962 -0.2848037765503677 0.11534225098381667 +20 ENSG0000010001 Tgd 109640 C T chr20:109640:C:T -433387 0.1340130856249374 0.6882036701446564 -0.4209735391443372 0.5835797209509345 +20 ENSG0000010001 Tgd 104677 T G chr20:104677:T:G 19618 0.6506314906138683 0.4249258793499959 0.027665558372723664 0.05271575828393323 +20 ENSG0000010001 Tgd 108657 C A chr20:108657:C:A -437322 0.09990527274524164 0.6967102552645917 -0.03915347211019404 0.2439655578560257 +20 ENSG0000010001 Tgd 105113 T A chr20:105113:T:A -159662 0.0920992116504813 0.0649229157728749 -0.5423200810978688 0.48189970394466675 +20 ENSG0000010001 Tgd 106760 T A chr20:106760:T:A 491206 0.8001877443103651 0.48588523863577693 0.09700667973780974 0.5492438635278605 +20 ENSG0000010001 Tgd 101595 A G chr20:101595:A:G 161506 0.524505505860474 0.4232446871786736 -0.742252166112237 0.7612251069969488 +20 ENSG0000010001 Tgd 100867 G A chr20:100867:G:A -350277 0.8637248458550404 0.8219681425257477 0.3130914002347378 0.24514672928730555 +20 ENSG0000010001 Tgd 101182 A G chr20:101182:A:G -465145 0.05279383200918275 0.19523767422310878 -0.6299610293069835 0.5027003040932526 +20 ENSG0000010001 Tgd 105493 C A chr20:105493:C:A 208082 0.32644092973703465 0.8309424008287891 -0.6636006491138544 0.7411595422735874 +20 ENSG0000010001 Tgd 101571 C T chr20:101571:C:T -471365 0.40371582216663404 0.4803996163358404 -0.7938064140820937 0.07631247934578694 +20 ENSG0000010001 Tgd 105239 T A chr20:105239:T:A -399916 0.9831039299064597 0.40179533827613945 0.7856729067839499 0.20660085733201897 +20 ENSG0000010001 Tgd 108509 C A chr20:108509:C:A -466963 0.9912138009035297 0.23210718385175577 0.9546300856337875 0.13136121341589857 +20 ENSG0000010001 Tgd 102886 A C chr20:102886:A:C -103869 0.1398381490634012 0.027531296727104304 0.9217605838664602 0.7394210393677298 +20 ENSG0000010001 Tgd 100760 T C chr20:100760:T:C 60133 0.3067472890695624 0.22362716179993802 -0.7979425014191406 0.22859709878340814 +20 ENSG0000010001 Tgd 102856 C T chr20:102856:C:T 42138 0.3788324367654089 0.9728575059528926 0.5932141425412483 0.15916553960750784 +20 ENSG0000010001 Tgd 109793 G C chr20:109793:G:C -150556 0.1262404189748938 0.3042792766218667 0.0011946022469968565 0.2991026326398742 +20 ENSG0000010001 Tgd 104882 A T chr20:104882:A:T -223482 0.5836498328447254 0.43004843167512685 -0.6133466472085911 0.1746937733417577 +20 ENSG0000010001 Tgd 100894 C T chr20:100894:C:T -41494 0.7503541965321977 0.6366573994608294 -0.05289312265660806 0.9050058240600126 +20 ENSG0000010001 Tgd 103974 T G chr20:103974:T:G 370713 0.23205334213533535 0.40476585801570997 0.5487940623181335 0.3352737355580144 +20 ENSG0000010001 Tgd 102910 A C chr20:102910:A:C 11626 0.7640306047888507 0.3900867250594584 -0.6845878903607736 0.7877466747316865 +20 ENSG0000010001 Tgd 108371 A G chr20:108371:A:G -63280 0.3001463048549472 0.2666010370309093 0.5655125527474159 0.370104439541372 +20 ENSG0000010001 Tgd 104084 G C chr20:104084:G:C -333011 0.28854359595594503 0.44153144789825893 0.984858750536624 0.27152412513554197 +20 ENSG0000010001 Tgd 106453 G C chr20:106453:G:C 199319 0.2333252380644073 0.20837832660371813 0.16112044004711668 0.6897103693858534 +20 ENSG0000010001 Tgd 106681 T C chr20:106681:T:C 284269 0.24984164650809737 0.2896361142586765 0.7548594610509749 0.7073670149238649 +20 ENSG0000010001 Tgd 106362 G T chr20:106362:G:T -187724 0.1032577554788795 0.4748210689559297 -0.6866915428496356 0.4582089083161046 +20 ENSG0000010001 Tgd 106855 T C chr20:106855:T:C -69220 0.5485287631193072 0.50021128914567 -0.14166819682194287 0.6690871299071117 +20 ENSG0000010001 Tgd 100429 G A chr20:100429:G:A -87599 0.7307290623962872 0.14711498689677638 0.13101351962073005 0.5906474665051442 +20 ENSG0000010001 Tgd 103873 A G chr20:103873:A:G -399147 0.35448463157150245 0.22460339720406242 0.8926810845746556 0.08421911424699867 +20 ENSG0000010001 Tgd 106450 T G chr20:106450:T:G -407323 0.029226930773579518 0.023121427723041044 0.6128061146768815 0.47450981907299095 +20 ENSG0000010001 Tgd 106219 A G chr20:106219:A:G 224705 0.16604617070418248 0.8300976512824497 -0.9918661424072854 0.09632339407202459 +20 ENSG0000010001 Tgd 108787 A T chr20:108787:A:T -94624 0.7319154908887929 0.5738408357501509 -0.7643507401374743 0.9792329610687762 +20 ENSG0000010001 Tgd 104678 G T chr20:104678:G:T 120917 0.7682137362498805 0.7829972265158659 -0.11595686678796158 0.18475959128135006 +20 ENSG0000010001 Tgd 104555 G C chr20:104555:G:C -138795 0.7506526217271349 0.20511481849224178 0.6318894057162838 0.5982500690801134 +20 ENSG0000010001 Tgd 107537 T C chr20:107537:T:C -488101 0.21523155566611585 0.8206594107498038 -0.4754710420127646 0.8466340802258165 +20 ENSG0000010001 Tgd 101310 A T chr20:101310:A:T 173218 0.41361144708481334 0.9110431997721471 0.43721056419807125 0.5675898020692498 +20 ENSG0000010001 Tgd 109023 C T chr20:109023:C:T 129231 0.1109375509087851 0.10487925973484336 -0.22074118096476547 0.17063845543976455 +20 ENSG0000010001 Tgd 109359 G T chr20:109359:G:T 95262 0.6016319563396919 0.7313816069446591 -0.9322252905157418 0.7545962526293286 +20 ENSG0000010001 Tgd 103190 T G chr20:103190:T:G 462217 0.665883551681504 0.8332307598146138 0.313582924009973 0.20591338087648495 +20 ENSG0000010001 Tgd 104484 A C chr20:104484:A:C -452195 0.8255245876561981 0.5454952925230744 0.38271066941771203 0.08952229694755397 +20 ENSG0000010001 Tgd 101018 A G chr20:101018:A:G 17602 0.6004954294600346 0.03769723381037582 0.987951029107651 0.908801006666269 +20 ENSG0000010001 Tgd 101494 A G chr20:101494:A:G -489072 0.9753195813516212 0.578341906178391 0.4207544563757608 0.6632538527476544 +20 ENSG0000010001 Tgd 101361 C T chr20:101361:C:T 437041 0.9118514883417823 0.1505221316936376 0.12364248679270884 0.881818513168483 +20 ENSG0000010001 Tgd 106833 A G chr20:106833:A:G 460473 0.5442912429515406 0.03298038056485142 0.929632754211928 0.8762948488088219 +20 ENSG0000010001 Tgd 109867 A T chr20:109867:A:T -193839 0.14437946023042414 0.9547731045308121 0.5394166290845301 0.25855914222778514 +20 ENSG0000010001 Tgd 105393 T A chr20:105393:T:A -280293 0.3192514866402877 0.07468713391920256 -0.8772331819629828 0.4785773067840098 +20 ENSG0000010001 Tgd 101576 G A chr20:101576:G:A -284614 0.920780700024554 0.38215757950217033 -0.8403250377785343 0.7874172360976924 +20 ENSG0000010001 Tgd 101621 A G chr20:101621:A:G -378359 0.20327817556936334 0.13523159014203312 0.41085063066722527 0.5833838055593022 +20 ENSG0000010001 Tgd 105070 A T chr20:105070:A:T -181805 0.9062122215623442 0.6690069054620841 -0.9913837885622387 0.9706787936234441 +20 ENSG0000010001 Tgd 108533 A C chr20:108533:A:C -403515 0.11923109838753942 0.8403827438773043 -0.08124686999493269 0.6323689170164978 +20 ENSG0000010001 Tgd 105196 T G chr20:105196:T:G 479251 0.697200380825124 0.7726070577609251 0.2151439668704085 0.9697830613307928 +20 ENSG0000010001 Tgd 107806 C G chr20:107806:C:G -100950 0.29456403002281706 0.4287032871508769 0.21039261030774692 0.2396032768156649 +20 ENSG0000010001 Tgd 101306 A G chr20:101306:A:G -183681 0.6146662009554044 0.11119875056759498 0.9717468526803079 0.12299211781974836 +20 ENSG0000010001 Tgd 109464 C T chr20:109464:C:T -238377 0.6414154928308111 0.11897039672993936 -0.4320822227451422 0.048837242804907324 +20 ENSG0000010001 Tgd 103891 A C chr20:103891:A:C -271626 0.33149624654203025 0.4109646424413619 0.3269188915691146 0.9658459449576415 +20 ENSG0000010001 Tgd 103040 G A chr20:103040:G:A -73733 0.5478675086294926 0.8141487564473896 -0.32572968054979023 0.9983419930923864 +20 ENSG0000010001 Tgd 102876 G C chr20:102876:G:C 436820 0.07505178453040562 0.13893068308380674 -0.27343171413249223 0.48707224154430073 +20 ENSG0000010001 Tgd 101066 G C chr20:101066:G:C 45884 0.5257118263460803 0.9098218706167343 -0.14816234424074404 0.60490451888773 +20 ENSG0000010001 Tgd 108302 T A chr20:108302:T:A -467887 0.369244226112715 0.5908470749140445 0.257336165022197 0.7307384847506313 +20 ENSG0000010001 Tgd 107090 G C chr20:107090:G:C 484696 0.6634080329314956 0.40189042842542533 -0.2687593644252173 0.7785186394032902 +20 ENSG0000010001 Tgd 104854 G A chr20:104854:G:A -22180 0.15606230787721476 0.4042073349153178 0.5208432920785269 0.3622636691308656 +20 ENSG0000010001 Tgd 106013 A C chr20:106013:A:C -98625 0.873964749336205 0.4764109404575477 0.3266736722414705 0.08392010281805855 +20 ENSG0000010001 Tgd 104497 A T chr20:104497:A:T -494659 0.9868286536515636 0.37807306281659014 0.29656396740258995 0.9610573756959909 +20 ENSG0000010001 Tgd 102950 C A chr20:102950:C:A 325704 0.7004336901899524 0.4450797124060194 0.6160533890516671 0.8770718400116485 +20 ENSG0000010001 Tgd 100057 A C chr20:100057:A:C 343272 0.759696275743027 0.48586147379558975 0.07259726734040073 0.008699966171686859 +20 ENSG0000010001 Tgd 106679 C T chr20:106679:C:T -353193 0.22936847167331897 0.5522141914671899 -0.6380374107511457 0.5565103286122394 +20 ENSG0000010001 Tgd 104652 A C chr20:104652:A:C -6077 0.3267421563441172 0.155544664904541 -0.6147904640746735 0.9999238017453975 +20 ENSG0000010001 Tgd 109684 C A chr20:109684:C:A -498649 0.2729195363243627 0.03901372646011325 0.5026186340189693 0.2687086088353302 +20 ENSG0000010001 Tgd 109918 A T chr20:109918:A:T -108855 0.889906851811374 0.10177984613575819 -0.7690775701997803 0.24702842268856048 +20 ENSG0000010001 Tgd 100487 C T chr20:100487:C:T -165836 0.9671820907277515 0.9436790827139934 0.8552911750319436 0.16556725309325243 +20 ENSG0000010001 Tgd 108694 T A chr20:108694:T:A 329995 0.9294809210053134 0.2892683008138849 0.2791131988198885 0.9360722265708439 +20 ENSG0000010001 Tgd 105889 G A chr20:105889:G:A 127882 0.7591708709624503 0.5241908523460037 -0.9415786992367245 0.9267076069556843 +20 ENSG0000010001 Tgd 100282 C A chr20:100282:C:A 152276 0.287698439583432 0.8667219185255097 0.8864444990370923 0.24334221965060387 +20 ENSG0000010001 Tgd 101265 C T chr20:101265:C:T 324855 0.7621124648342922 0.7609504528819779 -0.8087861399377152 0.6561307073933956 +20 ENSG0000010001 Tgd 104718 G C chr20:104718:G:C 268358 0.8837859528422956 0.12889283560665454 -0.9271746996747527 0.08591744701503104 +20 ENSG0000010001 Tgd 108355 T A chr20:108355:T:A -95747 0.22201302465802975 0.34435287488789756 0.9626775966991001 0.5596861520695159 +20 ENSG0000010001 Tgd 100409 T G chr20:100409:T:G 85431 0.5851828215502866 0.11540869375790941 -0.7081820652284194 0.22269670768144342 +20 ENSG0000010001 Tgd 107285 C T chr20:107285:C:T 361949 0.7204965904541124 0.5962613118865262 -0.9725184244075942 0.8145068788424265 +20 ENSG0000010001 Tgd 109053 G C chr20:109053:G:C 121130 0.5721650667940158 0.6978727412831474 -0.9582882591377013 0.7598009223042361 +20 ENSG0000010001 Tgd 103057 A G chr20:103057:A:G 132021 0.9647488030040667 0.5664387243809758 -0.9023221181411976 0.2987392782861502 +20 ENSG0000010001 Tgd 102511 G A chr20:102511:G:A -104412 0.0666775906673649 0.048470939610207764 -0.3368810799661486 0.46023804978543625 +20 ENSG0000010001 Tgd 103827 G C chr20:103827:G:C -110712 0.444052173895239 0.04323128672684984 -0.20185361328203388 0.14475772546764612 +20 ENSG0000010001 Tgd 106790 A T chr20:106790:A:T -61429 0.6638821479688493 0.06911211683482621 0.17549177853641362 0.5522852202544184 +20 ENSG0000010001 Tgd 102294 C T chr20:102294:C:T 165864 0.020495686769696042 0.2803528844896799 -0.042178739266306886 0.3990697997685465 +20 ENSG0000010001 Tgd 102634 G C chr20:102634:G:C -217563 0.30129398003095365 0.7738720017475167 -0.0022057166743090217 0.909488548205567 +20 ENSG0000010001 Tgd 105294 A C chr20:105294:A:C 208116 0.1841857004194578 0.7439466352823272 0.8019082583566344 0.1749347928120141 +20 ENSG0000010001 Tgd 104940 C A chr20:104940:C:A -23560 0.7094380417914616 0.3078142114774207 0.4402925719468893 0.3426660033788823 +20 ENSG0000010001 Tgd 106527 A C chr20:106527:A:C 60544 0.3380365693220889 0.458535889400457 0.6916890733940597 0.5853741152453301 +20 ENSG0000010001 Tgd 100472 G T chr20:100472:G:T 374613 0.4989875447981028 0.8089927463145824 -0.9701073890603851 0.27827286501510196 +20 ENSG0000010001 Tgd 106045 G A chr20:106045:G:A -249221 0.9967493844247527 0.21289491818564554 0.31431794381736067 0.6209620262312395 +20 ENSG0000010001 Tgd 105537 A C chr20:105537:A:C 171126 0.5378203535200847 0.8104301626928112 0.050721472306175075 0.22713346237722065 +20 ENSG0000010001 Tgd 104580 A T chr20:104580:A:T 134494 0.4350833549522607 0.18382099944964825 0.763492639216163 0.6176193895227771 +20 ENSG0000010001 Tgd 101486 G T chr20:101486:G:T -395973 0.4853729404173104 0.9512784790767305 0.2004775574629687 0.8293910756326537 +20 ENSG0000010001 Tgd 100434 C A chr20:100434:C:A -72946 0.46401072697024115 0.9276111853800612 -0.6463330849234383 0.1201042472110943 +20 ENSG0000010001 Tgd 103945 T G chr20:103945:T:G -98973 0.6041236088418667 0.4748390604439219 0.9810355131955864 0.005949304810306923 +20 ENSG0000010001 Tgd 103626 T C chr20:103626:T:C 288030 0.03301697202903375 0.21544883490435773 0.6780030463729518 0.5867830642441999 +20 ENSG0000010001 Tgd 108194 A C chr20:108194:A:C 57463 0.7802350218416828 0.8213236135117099 -0.9848201396324254 0.15207253295211623 +20 ENSG0000010001 Tgd 106849 A T chr20:106849:A:T 174220 0.24351864465807693 0.373671804510021 -0.5486141519336549 0.6045911274233934 +20 ENSG0000010001 Tgd 101389 T C chr20:101389:T:C -48812 0.0994500173388635 0.14622489500199154 0.6833726963477138 0.37719635427613957 +20 ENSG0000010001 Tgd 104601 G A chr20:104601:G:A 39096 0.7399619472657607 0.3538973627226609 0.19940421445823242 0.003454905996970868 +20 ENSG0000010001 Tgd 107365 A C chr20:107365:A:C 332487 0.779636057795053 0.7269563138768182 0.9548320504605055 0.13757971452293496 +20 ENSG0000010001 Tgd 103840 A G chr20:103840:A:G 182507 0.6275246178263655 0.46547320422566696 0.5636798968087824 0.7686111602738 +20 ENSG0000010001 Tgd 104668 C G chr20:104668:C:G -196306 0.44109214644072114 0.2879398527582495 -0.509874307454558 0.013835690979577271 +20 ENSG0000010001 Tgd 101938 T A chr20:101938:T:A 464686 0.08027945213079457 0.4513597560974578 -0.0020935024632784405 0.9692272678114432 +20 ENSG0000010001 Tgd 107013 C A chr20:107013:C:A -138660 0.17679514481748215 0.4709314007170693 0.792661514277246 0.41867238760612585 +20 ENSG0000010001 Tgd 102049 A T chr20:102049:A:T 80674 0.08654054121201393 0.7002932030558808 -0.35769564692988864 0.5478925379580938 +20 ENSG0000010001 Tgd 106665 T A chr20:106665:T:A 207969 0.11387718760066912 0.4784604283128945 0.09418893873322975 0.9274335495781693 +20 ENSG0000010001 Tgd 100394 G T chr20:100394:G:T -148413 0.24607443910452187 0.15116861610429355 0.3679107053025721 0.12398108469405712 +20 ENSG0000010001 Tgd 105829 T A chr20:105829:T:A 411217 0.13805949224942016 0.8187354477924027 0.03363346636983322 0.2851994007414162 +20 ENSG0000010001 Tgd 108399 C G chr20:108399:C:G -268611 0.91161483897254 0.08378804537003048 -0.42786599925453817 0.15306968581428937 +20 ENSG0000010001 Tgd 105105 T A chr20:105105:T:A -458013 0.028918005071280173 0.7464576530817241 -0.09288825347754237 0.337315401637079 +20 ENSG0000010001 Tgd 104025 A T chr20:104025:A:T -349843 0.2596530946892034 0.34457961171446894 0.3174111787433789 0.5027026443601046 +20 ENSG0000010001 Tgd 106228 G T chr20:106228:G:T -367031 0.9708987882640046 0.7549657371971141 0.07074527015694398 0.2585968461571501 +20 ENSG0000010001 Tgd 108043 T G chr20:108043:T:G -67217 0.34249851532373343 0.07157833786595347 0.9708633473638772 0.895621260338269 +20 ENSG0000010001 Tgd 108582 T A chr20:108582:T:A -401175 0.09836184068726916 0.27479089548661506 0.7415963862886108 0.8147105902839258 +20 ENSG0000010001 Tgd 105786 T G chr20:105786:T:G -87995 0.2928371145128392 0.43108257982966625 0.7315972863587168 0.876947541341995 +20 ENSG0000010001 Tgd 106043 A T chr20:106043:A:T 11549 0.18307869876491423 0.2796498635107477 0.8861342421982619 0.22138675504381847 +20 ENSG0000010001 Tgd 104079 G C chr20:104079:G:C 205315 0.39225188876699923 0.9303523060036519 -0.22819428721673707 0.4697924067858636 +20 ENSG0000010001 Tgd 106730 C G chr20:106730:C:G 36146 0.2935051738372487 0.42586048811482435 -0.6706265467601709 0.8143317678225591 +20 ENSG0000010001 Tgd 109466 C G chr20:109466:C:G 155857 0.13808979328648308 0.00581356852184145 -0.17344855400034098 0.1304842548051772 +20 ENSG0000010001 Tgd 109298 G C chr20:109298:G:C -98315 0.5338318789661622 0.33380284055134857 -0.7802857735306841 0.8186050092167828 +20 ENSG0000010001 Tgd 100889 G T chr20:100889:G:T 287159 0.4473100742385986 0.41789062105835917 -0.01561997563655515 0.5976797677927699 +20 ENSG0000010001 Tgd 103792 C A chr20:103792:C:A 143709 0.44084965872993154 0.7776261658632074 -0.4851987408874212 0.8774583786057054 +20 ENSG0000010001 Tgd 102269 A T chr20:102269:A:T 103484 0.11024704054863577 0.4370862310281136 0.5651611634603615 0.3718767878497638 +20 ENSG0000010001 Tgd 100072 T C chr20:100072:T:C 436356 0.49342769728205405 0.5501038654444068 0.7140615238185724 0.9349832236300925 +20 ENSG0000010001 Tgd 100103 T C chr20:100103:T:C -378138 0.8640189358573584 0.29130671693469945 0.31087850111632864 0.45949651146086395 +20 ENSG0000010001 Tgd 103336 A C chr20:103336:A:C -25223 0.5555005720305017 0.8408759157868788 0.8874871728575855 0.9475497896885443 +20 ENSG0000010001 Tgd 103982 T G chr20:103982:T:G 176444 0.7311365893545071 0.15606000791054597 -0.8877994280090211 0.5678186428771769 +20 ENSG0000010001 Tgd 104420 C A chr20:104420:C:A 252634 0.922528940399792 0.4882376596346575 0.531874593046961 0.44582176216497243 +20 ENSG0000010001 Tgd 106479 T G chr20:106479:T:G 160749 0.21970969938414053 0.1406247679047462 0.7257847455713646 0.9795527825817757 +20 ENSG0000010001 Tgd 108524 G T chr20:108524:G:T -495445 0.11282374014976326 0.9884395162635914 0.7665616988208195 0.8256158755823756 +20 ENSG0000010001 Tgd 108248 C T chr20:108248:C:T -93469 0.8171067778254096 0.7732348290435199 0.739355706321255 0.2043367044880104 +20 ENSG0000010001 Tgd 103482 G A chr20:103482:G:A 492997 0.7899835669212699 0.16638561292368748 0.9546266152164016 0.5407170893225578 +20 ENSG0000010001 Tgd 106644 G A chr20:106644:G:A 231184 0.20684549496464866 0.008727065114835786 -0.32886365592308375 0.6775012212614817 +20 ENSG0000010001 Tgd 109939 C G chr20:109939:C:G 419295 0.9159812226846364 0.13308078813572843 0.12458251394885278 0.3711011840500657 +20 ENSG0000010001 Tgd 106870 C A chr20:106870:C:A -380752 0.8670869558140428 0.1455713380988759 0.24326326503740514 0.7638341578788941 +20 ENSG0000010001 Tgd 101534 T C chr20:101534:T:C -447657 0.8248701665780236 0.9691233924776236 0.7492394000428082 0.0783678316114315 +20 ENSG0000010001 Tgd 105437 C G chr20:105437:C:G -384946 0.4751934434844599 0.7870831631096471 0.06119265728287693 0.6912321931994131 +20 ENSG0000010001 Tgd 100984 A T chr20:100984:A:T 497886 0.5239226649235813 0.5095710797390123 0.27784466381865913 0.7285248710480524 +20 ENSG0000010001 Tgd 100586 C A chr20:100586:C:A -214852 0.24199028360750063 0.3485709533517575 -0.23007583776675444 0.5094622158377657 +20 ENSG0000010001 Tgd 101243 T C chr20:101243:T:C -299794 0.5224406840973005 0.6545301608966874 -0.45111907251102346 0.6460805016608853 +20 ENSG0000010001 Tgd 107821 C G chr20:107821:C:G -164751 0.3522636108524042 0.049938680209852704 -0.9158744271924288 0.6395225443542765 +20 ENSG0000010001 Tgd 101690 G C chr20:101690:G:C -100039 0.2818322364045581 0.1099898553420473 0.6815898688978217 0.4513521680710162 +20 ENSG0000010001 Tgd 104297 A T chr20:104297:A:T 431740 0.46258967958621544 0.9118971873600629 -0.7945850431204076 0.8975602730863022 +20 ENSG0000010001 Tgd 108637 T G chr20:108637:T:G 235813 0.10283070382424775 0.09340882380830562 -0.2683727217323053 0.9279151643579673 +20 ENSG0000010001 Tgd 106952 G A chr20:106952:G:A -410675 0.5687502218133677 0.4700228111937771 0.6632089970317498 0.4391021888247996 +20 ENSG0000010001 Tgd 109489 T G chr20:109489:T:G -431137 0.4764903997613872 0.041684424276777765 -0.35830484532061946 0.02905579437692914 +20 ENSG0000010001 Tgd 108787 T C chr20:108787:T:C -301200 0.25558341560167863 0.6436238180035242 -0.8660523058762781 0.34842973383188264 +20 ENSG0000010001 Tgd 105361 G T chr20:105361:G:T 71927 0.36961751615191796 0.3647460337866494 -0.5211691262217033 0.24821765050980396 +20 ENSG0000010001 Tgd 109721 T C chr20:109721:T:C -333044 0.38789631724491513 0.6594581540079881 -0.8114713062625443 0.905516116939485 +20 ENSG0000010001 Tgd 107897 C A chr20:107897:C:A -430233 0.6813194478321886 0.5394258559821838 -0.46463070915593896 0.42589708677179533 +20 ENSG0000010001 Tgd 108980 G T chr20:108980:G:T -495491 0.8147872528059199 0.7763678148567211 -0.9870798565205201 0.7889044183933959 +20 ENSG0000010001 Tgd 105587 G T chr20:105587:G:T 2257 0.7539497866053033 0.42999750072156606 0.12035123722432584 0.64770164518622 +20 ENSG0000010001 Tgd 104179 C A chr20:104179:C:A 168961 0.3709753216132977 0.7386523612597613 -0.8775399898796303 0.3206152608890544 +20 ENSG0000010001 Tgd 108485 G A chr20:108485:G:A -249859 0.004418177930949563 0.5443685015076081 0.6363688735729964 0.941435509743921 +20 ENSG0000010001 Tgd 100126 G T chr20:100126:G:T 429039 0.7220603066859402 0.007972759298298993 -0.08664004854074547 0.8288227338011304 +20 ENSG0000010001 Tgd 109103 T G chr20:109103:T:G 331896 0.47511581681030024 0.45588054448257276 0.493790953608251 0.7559127118500893 +20 ENSG0000010001 Tgd 101981 C T chr20:101981:C:T -165463 0.1282716668642614 0.7324877640659471 0.30494644498756984 0.9216201669241934 +20 ENSG0000010001 Tgd 103251 A G chr20:103251:A:G 451477 0.08294418563266737 0.07318335807360665 0.6545606574648026 0.7166116585634048 +20 ENSG0000010001 Tgd 104566 G T chr20:104566:G:T 431605 0.6778104973160622 0.051829065001001595 0.4777187505162781 0.4839450411939436 +20 ENSG0000010001 Tgd 107325 G A chr20:107325:G:A 294182 0.6190435650513966 0.927919669327909 0.42362798606292973 0.42776599350378586 +20 ENSG0000010001 Tgd 101972 G A chr20:101972:G:A -105528 0.36476458392870925 0.6099138962812907 -0.30026598614631994 0.39936219410026996 +20 ENSG0000010001 Tgd 107459 G C chr20:107459:G:C -457332 0.6072556570872664 0.7234294167254972 -0.24474466556288044 0.8548397110499008 +20 ENSG0000010001 Tgd 103192 C T chr20:103192:C:T -330680 0.9361691312798862 0.8396260163303384 0.8899528553844938 0.9864271299376318 +20 ENSG0000010001 Tgd 106224 C T chr20:106224:C:T 318236 0.45889303553210936 0.20029075411847208 0.38911511275617716 0.12805694491379543 +20 ENSG0000010001 Tgd 101446 A C chr20:101446:A:C -244277 0.9840743290168564 0.703420423070231 -0.0826906111649992 0.36248392837931337 +20 ENSG0000010001 Tgd 104662 G T chr20:104662:G:T -58200 0.05006884606378548 0.11401766042839678 -0.014316457680004557 0.6408992150735638 +20 ENSG0000010001 Tgd 101873 A C chr20:101873:A:C -461054 0.7452216275192723 0.09618272665035887 -0.8615143985008387 0.7091303450761381 +20 ENSG0000010001 Tgd 102481 G A chr20:102481:G:A -467778 0.5039193632654599 0.134550313661439 -0.30270188211612337 0.5722487791184339 +20 ENSG0000010001 Tgd 103424 C G chr20:103424:C:G 453926 0.3362641081055504 0.4557143067085522 0.11261121807268015 0.8540367980532705 +20 ENSG0000010001 Tgd 103616 T C chr20:103616:T:C 15895 0.8944308987949701 0.6001230045176376 -0.7844060915158984 0.5708845701330657 +20 ENSG0000010001 Tgd 107734 A C chr20:107734:A:C -96924 0.2424659801296829 0.8962465130603354 0.010714544715392016 0.4137544430417287 +20 ENSG0000010001 Tgd 106347 C T chr20:106347:C:T 351771 0.15576633083034852 0.8765963927482696 -0.8167615094421619 0.99491963168799 +20 ENSG0000010001 Tgd 108108 T G chr20:108108:T:G -56157 0.3648671518732063 0.7786801868561481 -0.7160259588006446 0.39345254340162367 +20 ENSG0000010001 Tgd 105458 C T chr20:105458:C:T 255608 0.49805997811116687 0.1285356900848318 -0.9947725528568374 0.8110331604059655 +20 ENSG0000010001 Tgd 102315 A G chr20:102315:A:G 196328 0.04962949519128124 0.3041942094753659 0.49256593550727223 0.7901208305392455 +20 ENSG0000010001 Tgd 105237 G A chr20:105237:G:A -79894 0.954358485726285 0.20291821457172288 -0.8859598952664698 0.6453197131334091 +20 ENSG0000010001 Tgd 103247 T C chr20:103247:T:C 442250 0.42080858234327834 0.6554546796498912 -0.5658591481836228 0.5986744213033883 +20 ENSG0000010001 Tgd 103290 T A chr20:103290:T:A 79909 0.44336727649749164 0.11395805870829845 -0.9928969918259642 0.9405719011903767 +20 ENSG0000010001 Tgd 108712 A T chr20:108712:A:T 52313 0.6436971946239264 0.9483553858894181 -0.32815537305146014 0.9518874607861069 +20 ENSG0000010001 Tgd 101057 C T chr20:101057:C:T 155352 0.6829428155017819 0.6216375361352793 -0.539769738176928 0.9235389676783203 +20 ENSG0000010001 Tgd 103615 G A chr20:103615:G:A -245782 0.7703144283405257 0.3939081070601469 0.06757917875334596 0.6430545106061384 +20 ENSG0000010001 Tgd 108387 A T chr20:108387:A:T -356235 0.6743791150688336 0.42908935636217005 -0.8664403505803628 0.8531964670431459 +20 ENSG0000010001 Tgd 109373 C G chr20:109373:C:G 437562 0.6974075733228975 0.2564346177064146 -0.08400294412964326 0.004742136865430485 +20 ENSG0000010001 Tgd 105694 T A chr20:105694:T:A 368439 0.863164149208854 0.08827694532525432 0.9589563362129259 0.6811997743094836 +20 ENSG0000010001 Tgd 103475 T A chr20:103475:T:A 403891 0.6128729390550434 0.49719467706880405 -0.5943940042754967 0.4484167320885892 +20 ENSG0000010001 Tgd 108255 C T chr20:108255:C:T -400738 0.5576995505730028 0.9874354312180875 0.4939920799199451 0.14079088865666614 +20 ENSG0000010001 Tgd 106918 T G chr20:106918:T:G -71980 0.7334465374314364 0.3559782553288252 -0.9424367434163674 0.728744803396925 +20 ENSG0000010001 Tgd 106645 G A chr20:106645:G:A 33816 0.49523960410592127 0.39812847874859725 0.795883910734434 0.6585438465717405 +20 ENSG0000010001 Tgd 108892 T G chr20:108892:T:G 471858 0.23618752086492023 0.5447469467369065 0.8121041307568748 0.667101457485389 +20 ENSG0000010001 Tgd 100403 A G chr20:100403:A:G 421800 0.7759368403428554 0.6398802933206038 -0.08021952324631187 0.4021166045198266 +20 ENSG0000010001 Tgd 109702 A T chr20:109702:A:T -30714 0.6435813635370288 0.08562527559401356 -0.2096529604567514 0.817205839608161 +20 ENSG0000010001 Tgd 102770 T A chr20:102770:T:A -13671 0.2914339272736025 0.5837320405381731 0.6168469834028347 0.5660349774280576 +20 ENSG0000010001 Tgd 101740 T C chr20:101740:T:C -142018 0.6224868854628591 0.48027225185076283 -0.6954121525014325 0.32339335593996166 +20 ENSG0000010001 Tgd 109884 C A chr20:109884:C:A 75715 0.8386046155390215 0.9121349569934881 -0.26128497779977344 0.742310015243805 +20 ENSG0000010001 Tgd 100404 C A chr20:100404:C:A 469175 0.07243984131854775 0.7105824868469713 0.8701357586817264 0.12567365420187618 +20 ENSG0000010001 Tgd 107223 A G chr20:107223:A:G -154325 0.48284594380435386 0.5827123387789055 0.14331433281259254 0.953443987072571 +20 ENSG0000010001 Tgd 102279 C G chr20:102279:C:G -132035 0.801432386732195 0.5343831966286662 -0.1171976166922033 0.6486388758721694 +20 ENSG0000010001 Tgd 105053 G A chr20:105053:G:A -441194 0.8730374623200915 0.36106098274788123 -0.9128262250965418 0.7186809212480902 +20 ENSG0000010001 Tgd 103009 T G chr20:103009:T:G 88437 0.835270657308352 0.4912752982197759 0.27890401278518917 0.9924256181995547 +20 ENSG0000010001 Tgd 103817 A T chr20:103817:A:T 118293 0.19617694629742088 0.12349119113143792 0.4621728044329363 0.15077556229796635 +20 ENSG0000010001 Tgd 100217 A G chr20:100217:A:G 376203 0.6255640613744327 0.493407609129228 -0.6581692759451172 0.7544810767998557 +20 ENSG0000010001 Tgd 100377 G C chr20:100377:G:C -343516 0.9954635886934259 0.16205094178812152 0.7019641427551595 0.4086662346580876 +20 ENSG0000010001 Tgd 103455 G T chr20:103455:G:T 429495 0.04184772829443273 0.7824590351598381 -0.0030503475824199544 0.196370015887865 +20 ENSG0000010001 Tgd 102230 C T chr20:102230:C:T 448645 0.38489471116072127 0.710585656937022 -0.7222143521970159 0.7020472688535248 +20 ENSG0000010001 Tgd 109408 G C chr20:109408:G:C -249162 0.46957353461675866 0.7926050255803543 0.27011268270433475 0.9941481815938481 +20 ENSG0000010001 Tgd 105352 G A chr20:105352:G:A 345948 0.6420009863573325 0.2770894490560556 -0.21794347545449333 0.6636819615145776 +20 ENSG0000010001 Tgd 109791 C G chr20:109791:C:G 211237 0.7769727923595695 0.4960378054955018 -0.9006006014293269 0.3810489840746477 +20 ENSG0000010001 Tgd 108077 T C chr20:108077:T:C 177318 0.3039288837697507 0.9397442815652318 -0.5622603855373574 0.33097605022660664 +20 ENSG0000010001 Tgd 101075 C G chr20:101075:C:G 187149 0.429137378158595 0.5489730833111935 0.07291836533933882 0.8228985396654475 +20 ENSG0000010001 Tgd 105799 T C chr20:105799:T:C 31288 0.19829914559832884 0.29667354048463945 0.4828186907790546 0.22941225564248185 +20 ENSG0000010001 Tgd 105787 G T chr20:105787:G:T 396192 0.4164909186372533 0.49452342253799964 -0.13164682718161647 0.39224539641321093 +20 ENSG0000010001 Tgd 104911 C T chr20:104911:C:T -338250 0.02929853544143346 0.6629954264417591 -0.07855366956051801 0.3655536749064951 +20 ENSG0000010001 Tgd 107717 A C chr20:107717:A:C -244459 0.1590681059147384 0.8838217604938475 -0.18297361178020366 0.8043777039086366 +20 ENSG0000010001 Tgd 109190 T C chr20:109190:T:C -184624 0.24385505073716873 0.9753967577874675 -0.1387528628585213 0.5974659173326068 +20 ENSG0000010001 Tgd 105525 A C chr20:105525:A:C -475066 0.7631589675252118 0.7904455684542773 -0.3617454648061118 0.060513811445362616 +20 ENSG0000010001 Tgd 100523 T C chr20:100523:T:C -79634 0.46348108474303007 0.7328163595701138 -0.9836188994178681 0.45842775370833766 +20 ENSG0000010001 Tgd 107321 T G chr20:107321:T:G 451043 0.1418784919719125 0.9721095531455464 -0.37053544417558504 0.6353012831485308 +20 ENSG0000010001 Tgd 105659 A T chr20:105659:A:T 89538 0.9253761174423795 0.06343563960276632 -0.7245854685443269 0.5595355057255473 +20 ENSG0000010001 Tgd 105754 A C chr20:105754:A:C -459681 0.6765840435970966 0.6891276590317631 0.2720515430698627 0.3005974752937608 +20 ENSG0000010001 Tgd 105628 A T chr20:105628:A:T 89642 0.0942132719729235 0.20971772330565508 -0.5460483150971183 0.06566545314438559 +20 ENSG0000010001 Tgd 103667 G C chr20:103667:G:C -302773 0.07866936026131532 0.7215507233506696 0.811295272418415 0.11256365523557363 +20 ENSG0000010001 Tgd 103916 C A chr20:103916:C:A -211882 0.9937587072621081 0.16686982215274127 -0.2840605499647473 0.8850343550313887 +20 ENSG0000010001 Tgd 104329 T G chr20:104329:T:G 381320 0.6756440056883108 0.9061106904087859 0.6122487137889552 0.3446020646907276 +20 ENSG0000010001 Tgd 100838 C G chr20:100838:C:G -265702 0.5285297125014576 0.5540072077133683 0.35379414782073093 0.3492130329852033 +20 ENSG0000010001 Tgd 105607 A C chr20:105607:A:C 162616 0.756598982448793 0.9767991381956472 0.5963726580683664 0.8239733610596373 +20 ENSG0000010001 Tgd 101325 T C chr20:101325:T:C -401679 0.07839247194406729 0.6655622117361208 0.8463190541332426 0.34467601008689797 +20 ENSG0000010001 Tgd 105857 C T chr20:105857:C:T 222089 0.4537554733346225 0.0312506327316634 0.5297375979703518 0.136576743307951 +20 ENSG0000010001 Tgd 103056 A G chr20:103056:A:G -22240 0.1997963432032669 0.4422618541879936 -0.22945751107531276 0.9976898075833736 +20 ENSG0000010001 Tgd 102301 A C chr20:102301:A:C 370795 0.47562770079487404 0.9633227022229016 0.4382835883187306 0.7627339888484664 +20 ENSG0000010001 Tgd 102733 G C chr20:102733:G:C 425861 0.10150364170819393 0.7532574417018514 -0.9425052923903545 0.25828102985168505 +20 ENSG0000010001 Tgd 101942 T A chr20:101942:T:A 117774 0.621436252690176 0.05921076553982818 0.14203986874284413 0.08475243313538904 +20 ENSG0000010001 Tgd 107070 T A chr20:107070:T:A 328479 0.8440823572491956 0.9229471580569927 0.19542576873342865 0.9498705571046463 +20 ENSG0000010001 Tgd 107141 G A chr20:107141:G:A -174140 0.33558683866624606 0.712276930584983 0.44220715188302506 0.8216845441056998 +20 ENSG0000010001 Tgd 108845 T A chr20:108845:T:A 493675 0.17324338817796303 0.7605890275188761 -0.4392059626930265 0.22992258764771267 +20 ENSG0000010001 Tgd 108701 A C chr20:108701:A:C 26470 0.34415630139566256 0.9357599771801495 0.31514138418066984 0.6505626796417041 +20 ENSG0000010001 Tgd 100937 T C chr20:100937:T:C 137331 0.8159101548961668 0.400737861527353 -0.26746444335284925 0.859161992064434 +20 ENSG0000010001 Tgd 102372 A T chr20:102372:A:T -232245 0.13251462184921392 0.3618118894629825 -0.25782912311608475 0.3792181298292555 +20 ENSG0000010001 Tgd 103028 A C chr20:103028:A:C 159251 0.25876079644324257 0.8953001207491821 0.042674569053046785 0.7075407111415278 +20 ENSG0000010001 Tgd 104902 T G chr20:104902:T:G 425821 0.6150370491483222 0.22502386506908756 0.5910908443414631 0.8867120333917186 +20 ENSG0000010001 Tgd 102569 C A chr20:102569:C:A -72181 0.14707737925141995 0.5845465668640456 0.8974474768809466 0.9361915087046606 +20 ENSG0000010001 Tgd 109912 T G chr20:109912:T:G 447126 0.782259262799804 0.3397320271201272 -0.8715374632224149 0.4524625689269291 +20 ENSG0000010001 Tgd 102650 A G chr20:102650:A:G -351884 0.6853083417891241 0.08338122623890087 -0.8928496132619044 0.5039163110009031 +20 ENSG0000010001 Tgd 103746 A T chr20:103746:A:T -83642 0.5672001086167439 0.07551601370309469 -0.35547398861268786 0.21861336082009966 +20 ENSG0000010001 Tgd 107545 C T chr20:107545:C:T 92319 0.5138447708073604 0.4512208885500125 -0.9980423533607883 0.6438258516022972 +20 ENSG0000010001 Tgd 105674 A C chr20:105674:A:C 405328 0.19649674785494575 0.2542955374282899 -0.3644079558384652 0.011341930009839234 +20 ENSG0000010001 Tgd 102910 A T chr20:102910:A:T 313814 0.6462019486522952 0.7424012557187424 0.04148611789995149 0.5609008623426621 +20 ENSG0000010001 Tgd 109093 A T chr20:109093:A:T 280954 0.9401320689147605 0.6379512052701422 0.7609955229653449 0.17093090528138644 +20 ENSG0000010001 Tgd 103896 A C chr20:103896:A:C -491078 0.6045869796042972 0.7188265903940726 -0.588569115502499 0.408678858802909 +20 ENSG0000010001 Tgd 107525 A T chr20:107525:A:T -248244 0.7888076784012029 0.5417035334183917 -0.8074834638140573 0.07644145861102003 +20 ENSG0000010001 Tgd 103991 T G chr20:103991:T:G -319097 0.07167095727077255 0.8713475447173606 -0.37285585552262246 0.24444069124253556 +20 ENSG0000010001 Tgd 101648 C T chr20:101648:C:T -343870 0.0029220066855851767 0.2350214089111774 0.31506786565340916 0.1698899148277967 +20 ENSG0000010001 Tgd 103868 T A chr20:103868:T:A 308397 0.5501732508855467 0.19698685918108605 0.4624081563472353 0.8816023597233642 +20 ENSG0000010001 Tgd 106337 A G chr20:106337:A:G -266940 0.41533592224937754 0.009037593286924217 0.07494206078857601 0.6770600774727527 +20 ENSG0000010001 Tgd 101409 G T chr20:101409:G:T 274142 0.38037561327392355 0.012630361809258361 0.49817235038102736 0.5929184552932114 +20 ENSG0000010001 Tgd 105018 G T chr20:105018:G:T -451585 0.04274174588274027 0.3535881871685501 -0.8384149930331237 0.6990506268408455 +20 ENSG0000010001 Tgd 101634 A G chr20:101634:A:G 457690 0.008834983831286447 0.11413990284280184 -0.5171116252393388 0.5610679819793899 +20 ENSG0000010001 Tgd 100452 C A chr20:100452:C:A -310939 0.21669158681316525 0.006419759460436714 -0.2573712009053384 0.7649830663503635 +20 ENSG0000010001 Tgd 109571 A C chr20:109571:A:C 337337 0.6425821580285742 0.36180708005682904 0.8694802576805445 0.4208954163707972 +20 ENSG0000010001 Tgd 107744 T G chr20:107744:T:G -139168 0.3384315326026477 0.8227025875067985 0.20007963755822744 0.45406600680469206 +20 ENSG0000010001 Tgd 108168 A T chr20:108168:A:T -39476 0.44614723126859623 0.6843553320384107 -0.767341961143932 0.7554934891615354 +20 ENSG0000010001 Tgd 108209 G T chr20:108209:G:T 387574 0.4256570506134455 0.584654311495836 -0.19841599305642021 0.13533753858836767 +20 ENSG0000010001 Tgd 106582 T A chr20:106582:T:A -109663 0.36345641683354135 0.20747322930966605 -0.8031088382661764 0.5449261364804303 +20 ENSG0000010001 Tgd 108598 G C chr20:108598:G:C 363150 0.992752991963463 0.1658732647406952 -0.7204202828196378 0.6877031876267602 +20 ENSG0000010001 Tgd 104730 G A chr20:104730:G:A -183408 0.2971193700094438 0.3909823066424306 -0.23747351503508174 0.49474483360974975 +20 ENSG0000010001 Tgd 103356 T A chr20:103356:T:A -188724 0.9514280757306273 0.11044998520328375 0.6110720255535662 0.41667985955891124 +20 ENSG0000010001 Tgd 101586 C T chr20:101586:C:T 156628 0.6709423221816576 0.3745932592866482 -0.4089568181133465 0.22753745364086286 +20 ENSG0000010001 Tgd 109847 T G chr20:109847:T:G -225345 0.47919780781278865 0.8417189139891559 -0.22340371738085563 0.37773056873015437 +20 ENSG0000010001 Tgd 109264 A T chr20:109264:A:T -104263 0.551206481149291 0.779409698853576 -0.5373467951567485 0.029278507307362797 +20 ENSG0000010001 Tgd 108869 T G chr20:108869:T:G 216084 0.603351391259835 0.6406964602160256 -0.1968708823779748 0.2277861626848962 +20 ENSG0000010001 Tgd 101291 C T chr20:101291:C:T 283097 0.9520886029673132 0.7794643562655656 0.41389374416815095 0.9480919803996776 +20 ENSG0000010001 Tgd 101862 T G chr20:101862:T:G 480462 0.057651090497536694 0.32983055411510254 -0.5538915950036116 0.06534951389310743 +20 ENSG0000010001 Tgd 104330 A G chr20:104330:A:G 278910 0.9366413703977409 0.1451539440379248 -0.8116243618435264 0.5436728816420656 +20 ENSG0000010001 Tgd 102791 C G chr20:102791:C:G -369896 0.5185938864393498 0.020422250684388743 0.07294711640794138 0.44690367831160704 +20 ENSG0000010001 Tgd 109559 G A chr20:109559:G:A 389173 0.8273833578859155 0.3346658101465194 -0.10360082200437382 0.6132091573131772 +20 ENSG0000010001 Tgd 108531 C G chr20:108531:C:G 437835 0.2848594679060227 0.6143004182636417 0.24856425226133227 0.057823342900038495 +20 ENSG0000010001 Tgd 102642 T A chr20:102642:T:A 14150 0.12423881970628237 0.2791593488029037 0.7073346139374221 0.7907369082228533 +20 ENSG0000010001 Tgd 106841 C A chr20:106841:C:A 79749 0.6198110545764651 0.6629095830172708 0.9898017785025508 0.8914944597552172 +20 ENSG0000010001 Tgd 100155 G A chr20:100155:G:A 16440 0.2112593176353168 0.8007886833303521 0.7083118998642086 0.8653921079401619 +20 ENSG0000010001 Tgd 105135 G T chr20:105135:G:T -400687 0.9931534261102574 0.2001162605664918 -0.8117632393812693 0.5967813039685588 +20 ENSG0000010001 Tgd 106006 C G chr20:106006:C:G 357710 0.1780084725085378 0.8667340409256106 -0.17116452599531806 0.41913385816728177 +20 ENSG0000010001 Tgd 104999 G T chr20:104999:G:T 11708 0.913855951730562 0.5071165715979828 -0.8226400826281499 0.8393410202841858 +20 ENSG0000010001 Tgd 103462 A G chr20:103462:A:G 56166 0.9780297946017946 0.1666896618731274 -0.9052777273382449 0.7638461959509127 +20 ENSG0000010001 Tgd 100213 G A chr20:100213:G:A -53288 0.991108152968821 0.34805901489053015 0.5906892222653 0.6959117357624233 +20 ENSG0000010001 Tgd 101883 G T chr20:101883:G:T 341456 0.9836696363318943 0.1944699542342997 0.8418464082559098 0.802528102679111 +20 ENSG0000010001 Tgd 103967 A G chr20:103967:A:G 143742 0.8609828317678228 0.3294229229372805 0.1567913895343387 0.7545586630853774 +20 ENSG0000010001 Tgd 100744 C A chr20:100744:C:A -245540 0.47622162604745755 0.16334219724965537 -0.2854857035020728 0.29655768208354666 +20 ENSG0000010001 Tgd 108453 C T chr20:108453:C:T -141653 0.6948445917747763 0.9038053674078426 0.6406577954824979 0.23518559401037087 +20 ENSG0000010001 Tgd 109793 A T chr20:109793:A:T 5234 0.8506113982085262 0.9991905222275694 -0.5643454849160219 0.6324854530243056 +20 ENSG0000010001 Tgd 102384 A G chr20:102384:A:G 348006 0.2723290627430367 0.8336268559113061 0.40112776666531946 0.18507186035326553 +20 ENSG0000010001 Tgd 109137 A C chr20:109137:A:C 372490 0.49353102496002843 0.4209718398603074 -0.6409917040973361 0.9351232605515971 +20 ENSG0000010001 Tgd 102986 T G chr20:102986:T:G 350497 0.037322656225519446 0.6962135027498007 -0.20967006335748795 0.5718768747943335 +20 ENSG0000010001 Tgd 104279 A T chr20:104279:A:T 258464 0.7725603696320855 0.2516891234989391 -0.532491652759671 0.3146373204232915 +20 ENSG0000010001 Tgd 103566 A T chr20:103566:A:T -490902 0.894756300537381 0.80097972952048 0.1956316143265786 0.5217951199547651 +20 ENSG0000010001 Tgd 105533 A G chr20:105533:A:G 229560 0.6616018362779457 0.3623624658728337 0.5765198555483646 0.5388409505959533 +20 ENSG0000010001 Tgd 102222 C A chr20:102222:C:A 89722 0.9852714892421537 0.6112789556782817 0.732487308619052 0.7029155866541231 +20 ENSG0000010001 Tgd 107552 G T chr20:107552:G:T -155415 0.6508504744299355 0.7604346865842437 -0.8141046849111164 0.40105962301577663 +20 ENSG0000010001 Tgd 101055 A T chr20:101055:A:T -273726 0.9629911007113758 0.4704685374506523 0.8686110888241578 0.45336844113285885 +20 ENSG0000010001 Tgd 107836 T A chr20:107836:T:A 2081 0.6568623202023126 0.7066124252508152 0.9492419363737874 0.7066408569437396 +20 ENSG0000010001 Tgd 102954 C T chr20:102954:C:T 182052 0.17165085409834469 0.17073600541781841 0.701967953817493 0.2711024582010772 +20 ENSG0000010001 Tgd 108606 T A chr20:108606:T:A -68202 0.6737093546417557 0.24563355136534193 0.4670392905874323 0.4344456249427689 +20 ENSG0000010001 Tgd 105056 A C chr20:105056:A:C -195715 0.2684554768219284 0.29653088570221686 0.9440480105988218 0.8727425423052431 +20 ENSG0000010001 Tgd 104436 T A chr20:104436:T:A -335016 0.693127254244019 0.24465072757385542 0.6735680811693923 0.3684878496700193 +20 ENSG0000010001 Tgd 109846 C G chr20:109846:C:G -68666 0.3510372839983681 0.8944455902127915 -0.8182773274479014 0.6686393523819951 +20 ENSG0000010001 Tgd 108434 G A chr20:108434:G:A -147298 0.41652843348453483 0.2739644349222211 0.22537719909409581 0.5763821767324369 +20 ENSG0000010001 Tgd 101689 C G chr20:101689:C:G -131370 0.19240551159528763 0.5391517029705736 0.41336254872312583 0.8973576159054628 +20 ENSG0000010001 Tgd 107659 A C chr20:107659:A:C -173845 0.8308180245480499 0.1342351309961224 0.677541409802257 0.9901281624678177 +20 ENSG0000010001 Tgd 101247 T C chr20:101247:T:C -98049 0.31952497822420967 0.26716780052511835 0.4986978706405638 0.5940386782444007 +20 ENSG0000010001 Tgd 102875 A T chr20:102875:A:T -246390 0.4802849023210335 0.7111249892533174 -0.1344355406897364 0.6643011032164462 +20 ENSG0000010001 Tgd 106938 C T chr20:106938:C:T -257032 0.5372594623545063 0.0932705295732702 -0.4999033198823757 0.8349295677345959 +20 ENSG0000010001 Tgd 108877 T A chr20:108877:T:A 376373 0.6211114286858553 0.23049530970634247 0.587982897543069 0.1276897413891721 +20 ENSG0000010001 Tgd 102438 C A chr20:102438:C:A -103066 0.42463985587170383 0.17767466986467906 0.48935967963666704 0.27088874596134865 +20 ENSG0000010001 Tgd 103135 T C chr20:103135:T:C 207312 0.5173923264354314 0.6045079248403918 0.9045439547021683 0.25809691422788994 +20 ENSG0000010001 Tgd 107744 C A chr20:107744:C:A 484687 0.9570662285207036 0.5268101422581742 -0.1276400103788098 0.6126817484732524 +20 ENSG0000010001 Tgd 100611 G C chr20:100611:G:C 351375 0.2879701120833148 0.28427879697896064 0.45491678360134347 0.17741845492523392 +20 ENSG0000010001 Tgd 102189 A G chr20:102189:A:G -217946 0.20420242354293028 0.8211924942796218 -0.9565822545048934 0.8621068565402085 +20 ENSG0000010001 Tgd 102673 G A chr20:102673:G:A -239179 0.5693182232001424 0.8066686012171741 0.21009829452074325 0.9602056732217035 +20 ENSG0000010001 Tgd 104643 C T chr20:104643:C:T -161608 0.6009397141346792 0.8395068635187081 -0.0593517958394052 0.32880917882738087 +20 ENSG0000010001 Tgd 104238 G A chr20:104238:G:A 341553 0.5494479203450209 0.201409153674023 -0.924728829234509 0.592325953054216 +20 ENSG0000010001 Tgd 109646 T G chr20:109646:T:G -277423 0.9345614632574594 0.9859550989031935 0.4791437794227278 0.6109100929156777 +20 ENSG0000010001 Tgd 106586 C G chr20:106586:C:G -482803 0.40858300552365345 0.106491718125165 0.40056015332568484 0.855281635044778 +20 ENSG0000010001 Tgd 100365 G A chr20:100365:G:A -410868 0.8462793324951995 0.621225479545554 0.8163700115984003 0.08171278107382766 +20 ENSG0000010001 Tgd 103521 C G chr20:103521:C:G -392386 0.33672234708211557 0.48043445370546933 -0.28300682576252045 0.4327029828888753 +20 ENSG0000010001 Tgd 105338 A C chr20:105338:A:C -419707 0.5428195426461944 0.5051831858037225 0.8873655799031674 0.6865387504311353 +20 ENSG0000010001 Tgd 106298 G C chr20:106298:G:C -226574 0.5629751226813973 0.7232045060626462 -0.6385960250435743 0.28480251107066834 +20 ENSG0000010001 Tgd 103400 C G chr20:103400:C:G 103438 0.5171229118679926 0.01864654483603989 0.9528098105220981 0.9264253317412778 +20 ENSG0000010001 Tgd 105312 A C chr20:105312:A:C 319503 0.40896075523293374 0.8568721317306868 0.15322829471510357 0.9484432859800519 +20 ENSG0000010001 Tgd 107938 A T chr20:107938:A:T 364890 0.7119330670639124 0.9012008701584748 0.8024821009926151 0.7956093837725302 +20 ENSG0000010001 Tgd 107122 A G chr20:107122:A:G 371826 0.703007910676743 0.5878273782716589 0.7990173299779457 0.8017357562426991 +20 ENSG0000010001 Tgd 102038 C A chr20:102038:C:A 385506 0.13005306817917828 0.05569703117264535 0.7244086814297568 0.8594058331808205 +20 ENSG0000010001 Tgd 108830 C G chr20:108830:C:G -51386 0.7445681778522555 0.7555698929458265 0.7490887616712072 0.3015536459881668 +20 ENSG0000010001 Tgd 101169 G T chr20:101169:G:T 42430 0.6468250325882591 0.5729702356792524 0.5174818597533557 0.4077966928898688 +20 ENSG0000010001 Tgd 109164 A G chr20:109164:A:G -294624 0.3230762743364939 0.3507939593548678 -0.9621093314872622 0.8400585841126408 +20 ENSG0000010001 Tgd 100357 A T chr20:100357:A:T -39387 0.5492714835562229 0.37737250775905085 -0.3330729442229994 0.9668711850919276 +20 ENSG0000010001 Tgd 103415 A C chr20:103415:A:C 173920 0.9206606783249608 0.859654384619545 -0.7051405175544139 0.8683585614323505 +20 ENSG0000010001 Tgd 108024 G C chr20:108024:G:C 49643 0.3760478404088816 0.47484814411977416 0.7830671402250957 0.3879039637984361 +20 ENSG0000010001 Tgd 106799 T A chr20:106799:T:A 491276 0.1943030264031732 0.42246202540123423 -0.4925411298268352 0.6803228227419976 +20 ENSG0000010001 Tgd 103462 C G chr20:103462:C:G 33379 0.7808830186556979 0.3775199632883699 0.47749906359211836 0.24536055037674695 +20 ENSG0000010001 Tgd 101720 A T chr20:101720:A:T -294295 0.22235031702208352 0.43974442541321757 -0.15664213763509305 0.47730101205669595 +20 ENSG0000010001 Tgd 100784 G T chr20:100784:G:T 378914 0.12403187815777061 0.4465006016303088 -0.4401191343905484 0.35797071777673883 +20 ENSG0000010001 Tgd 107563 G T chr20:107563:G:T 208000 0.41347643651211397 0.13590486636850363 -0.50999401594399 0.39302090070435175 +20 ENSG0000010001 Tgd 108818 C A chr20:108818:C:A 34186 0.6142532073090139 0.9094897624423205 0.8296602351438203 0.6058480636842292 +20 ENSG0000010001 Tgd 108125 C G chr20:108125:C:G 310951 0.8586901677722765 0.6132757311509176 0.36827667484960425 0.6504131701379089 +20 ENSG0000010001 Tgd 104674 C T chr20:104674:C:T 115968 0.354141599300814 0.19025821571145296 0.4998091527774302 0.7874242756105673 +20 ENSG0000010001 Tgd 100451 T G chr20:100451:T:G -91797 0.46573094591417585 0.5575726514706 -0.4372148957100186 0.2658732855561912 +20 ENSG0000010001 Tgd 102463 A G chr20:102463:A:G -58287 0.46724588688233104 0.08051709315274191 0.19354563124704582 0.3513815361225719 +20 ENSG0000010001 Tgd 104884 C G chr20:104884:C:G 303765 0.20769715049669657 0.7769557253119418 -0.8812100496591588 0.5887721953476269 +20 ENSG0000010001 Tgd 100530 A C chr20:100530:A:C 274346 0.033497138293897666 0.4090411839827943 -0.2031440085609506 0.726246549574542 +20 ENSG0000010001 Tgd 102458 T C chr20:102458:T:C 257440 0.2633915569141899 0.24416616205374697 0.9663819068460187 0.8006897128015656 +20 ENSG0000010001 Tgd 106925 C T chr20:106925:C:T -141433 0.9538311003170414 0.9137880966088533 0.7298383813624678 0.13100354688275676 +20 ENSG0000010001 Tgd 106744 G A chr20:106744:G:A 161963 0.6835383021490395 0.9154506375723099 0.5253833087307029 0.8618392433451111 +20 ENSG0000010001 Tgd 100604 C G chr20:100604:C:G -469693 0.8554672002758067 0.5706198791925796 -0.8426372547426884 0.06087007220742599 +20 ENSG0000010001 Tgd 104023 G A chr20:104023:G:A -417515 0.6000070399748897 0.7653832554657317 0.003728428001651407 0.591977800181975 +20 ENSG0000010001 Tgd 106539 C A chr20:106539:C:A -409022 0.5476185687020593 0.6828472829366584 -0.36343687024142723 0.2158213911662018 +20 ENSG0000010001 Tgd 107338 C G chr20:107338:C:G -52903 0.07650078320472653 0.7301662363589753 -0.05923233257714977 0.4256251705914251 +20 ENSG0000010001 Tgd 101524 A C chr20:101524:A:C 255548 0.4615582729360286 0.5835503742963727 -0.20020942879893378 0.6512476091656155 +20 ENSG0000010001 Tgd 106282 T A chr20:106282:T:A 276338 0.37286394619952734 0.133167232341022 -0.19176786626736164 0.9779728129416592 +20 ENSG0000010001 Tgd 109604 C A chr20:109604:C:A 52341 0.6419038669677389 0.06779940632154324 0.4366581315408835 0.7016822534981205 +20 ENSG0000010001 Tgd 103794 A T chr20:103794:A:T 102146 0.7043716846848712 0.49637959467480375 0.8165362817909216 0.855510037722675 +20 ENSG0000010001 Tgd 105170 C G chr20:105170:C:G 213460 0.24196914302663297 0.5350299211020099 -0.6505296392049527 0.15641048605008603 +20 ENSG0000010001 Tgd 104152 A C chr20:104152:A:C -429502 0.21628145780913977 0.08823942789386297 -0.22290044462537129 0.03319928791387873 +20 ENSG0000010001 Tgd 107939 C G chr20:107939:C:G 409760 0.24363598386357743 0.5517632930783984 0.6760169877154927 0.25407711226738366 +20 ENSG0000010001 Tgd 108198 C T chr20:108198:C:T -226165 0.4552071712853929 0.8647440023902473 0.6552276183396917 0.0036600941925467516 +20 ENSG0000010001 Tgd 105363 G T chr20:105363:G:T 379024 0.3573487847455754 0.0820867235755216 0.8315533660012309 0.6822766400425259 +20 ENSG0000010001 Tgd 106657 G C chr20:106657:G:C 470636 0.8670640801230635 0.4969005769421606 -0.39510732746851396 0.2045831903299867 +20 ENSG0000010001 Tgd 108282 T A chr20:108282:T:A -351780 0.3553414979138726 0.37388804700669176 -0.46492850928452634 0.9447317151689855 +20 ENSG0000010001 Tgd 106856 C A chr20:106856:C:A -133773 0.2100373875414301 0.6220007683013751 0.05445640945166641 0.5384263823949935 +20 ENSG0000010001 Tgd 102750 A G chr20:102750:A:G 77112 0.6023174176206316 0.3437272003056433 0.2452356190492384 0.6202568437220749 +20 ENSG0000010001 Tgd 109460 C A chr20:109460:C:A 461202 0.17080913462583414 0.997959111288194 0.9584122356043474 0.33096178648356295 +20 ENSG0000010001 Tgd 108501 A G chr20:108501:A:G -16905 0.34516183851583593 0.6208336590067633 -0.5697356382304888 0.2063284841293214 +20 ENSG0000010001 Tgd 101591 T C chr20:101591:T:C 58359 0.7622046094730042 0.5719396776832629 0.09546330409539627 0.7167603046272988 +20 ENSG0000010001 Tgd 100673 A T chr20:100673:A:T 58754 0.0650306554073411 0.25820093502215014 -0.22964103238167488 0.2598565960899601 +20 ENSG0000010001 Tgd 109941 T C chr20:109941:T:C 459161 0.1569861926346744 0.6891373888273996 0.752603119164339 0.5746590488020105 +20 ENSG0000010001 Tgd 103968 T A chr20:103968:T:A 40027 0.3143948030079725 0.472181900624951 -0.6136160895944831 0.09158723157015508 +20 ENSG0000010001 Tgd 101428 C G chr20:101428:C:G -407599 0.19664183444871441 0.0838474581564973 0.7653076595233874 0.3570021053186116 +20 ENSG0000010001 Tgd 103208 C T chr20:103208:C:T -459115 0.1898093078947518 0.8084673531898248 -0.4063348768612336 0.45033047113947655 +20 ENSG0000010001 Tgd 108730 A G chr20:108730:A:G -121923 0.6139113794939933 0.3030791704628153 0.5361077832112027 0.3204469071936748 +20 ENSG0000010001 Tgd 106665 G T chr20:106665:G:T 285710 0.8002200819956271 0.32553632548416644 0.77269044970834 0.12055967316256735 +20 ENSG0000010001 Tgd 109149 T A chr20:109149:T:A -351775 0.4066096539702978 0.6138746057278438 0.8096790253810751 0.2676337753750529 +20 ENSG0000010001 Tgd 102502 A G chr20:102502:A:G -178312 0.6844359195383942 0.9349356116214665 0.8347220083138729 0.8038877263283417 +20 ENSG0000010001 Tgd 100376 G A chr20:100376:G:A 462297 0.6947746258095878 0.3824452682003554 0.28143300683104067 0.6903316989261181 +20 ENSG0000010001 Tgd 101529 C T chr20:101529:C:T 338925 0.7400534162185929 0.4044978435005786 -0.7172092882185692 0.8244026107933696 +20 ENSG0000010001 Tgd 102064 T A chr20:102064:T:A 163559 0.8105522133351962 0.35583964681529 0.27607319358152793 0.171328718667724 +20 ENSG0000010001 Tgd 106243 G T chr20:106243:G:T -468043 0.5290781348463351 0.6314271932169054 -0.006861305640113224 0.7998313234036141 +20 ENSG0000010001 Tgd 101415 C T chr20:101415:C:T -354089 0.6620487183306587 0.6341448324423462 0.8449675133374712 0.9472366310798925 +20 ENSG0000010001 Tgd 105763 G T chr20:105763:G:T 296984 0.13266922199180875 0.6272972707142312 -0.9016873731693746 0.2020355041901972 +20 ENSG0000010001 Tgd 102389 G C chr20:102389:G:C 86003 0.3396003143167837 0.4933457727358942 -0.7423642388867047 0.8052564069493354 +20 ENSG0000010001 Tgd 109118 G A chr20:109118:G:A -348221 0.6100602176014196 0.08837230723531231 -0.330645767058934 0.9010666059292941 +20 ENSG0000010001 Tgd 100733 C A chr20:100733:C:A 240815 0.9297476719872642 0.913527508316578 0.8954503166080778 0.40003422398805355 +20 ENSG0000010001 Tgd 106228 A C chr20:106228:A:C 79252 0.028679916065204925 0.7912949169822246 0.6635070619274506 0.26288525694445464 +20 ENSG0000010001 Tgd 106857 G C chr20:106857:G:C -26930 0.9546193465936453 0.39913938710533114 0.9594604910461182 0.9660729357058131 +20 ENSG0000010001 Tgd 100683 A C chr20:100683:A:C 412916 0.08343157644990318 0.5026764569584455 0.45735412216817806 0.5055543938737476 +20 ENSG0000010001 Tgd 107138 G C chr20:107138:G:C -285842 0.03527715872055548 0.9005800514588412 -0.34154218991093366 0.8411566338767462 +20 ENSG0000010001 Tgd 107069 G C chr20:107069:G:C -53760 0.6972569598446497 0.9113226009655447 0.22668484782338605 0.8297583353476027 +20 ENSG0000010001 Tgd 101214 T G chr20:101214:T:G 191013 0.958981588873765 0.41669046615924177 -0.7440461086474497 0.9275508212738784 +20 ENSG0000010001 Tgd 109693 A T chr20:109693:A:T 83021 0.3821905628526323 0.9221049120980664 -0.03601119174498546 0.5895325871394359 +20 ENSG0000010001 Tgd 107328 T A chr20:107328:T:A -282615 0.32927097470501954 0.759927985973887 0.46055256212280593 0.8569810531123225 +20 ENSG0000010001 Tgd 108537 C T chr20:108537:C:T 87327 0.16848844253076922 0.7182581169123784 -0.4203034593457027 0.07434442893067156 +20 ENSG0000010001 Tgd 102000 C G chr20:102000:C:G 348171 0.5633577758899107 0.04777962682420889 -0.2766254658496614 0.3083178577949051 +20 ENSG0000010001 Tgd 102100 T C chr20:102100:T:C 425583 0.09297574279690357 0.7354165569606377 -0.051535767092513174 0.6399651131945785 +20 ENSG0000010001 Tgd 109248 C T chr20:109248:C:T -367781 0.6575079838197955 0.39384320000875284 -0.984346929075891 0.5570365958704923 +20 ENSG0000010001 Tgd 108365 C G chr20:108365:C:G 222224 0.6608295302782187 0.5930011860349692 -0.666401976830364 0.7745240690102373 +20 ENSG0000010001 Tgd 108763 T A chr20:108763:T:A 297060 0.7639417284040381 0.5269423292453124 -0.6914751791139047 0.37414309670372986 +20 ENSG0000010001 Tgd 100684 G C chr20:100684:G:C -52160 0.5351778323016545 0.29802605272463223 0.8842434560031165 0.4229829008316509 +20 ENSG0000010001 Tgd 106710 G A chr20:106710:G:A 140482 0.949090066546378 0.2785418802793902 0.6034203253934391 0.2195920713853118 +20 ENSG0000010001 Tgd 104405 G C chr20:104405:G:C -346322 0.07934941523560135 0.3574142130924639 -0.5986677843159298 0.9376906519241506 +20 ENSG0000010001 Tgd 105282 T G chr20:105282:T:G -212127 0.537449044797849 0.4573540014428493 -0.4471317963751318 0.9670010147105559 +20 ENSG0000010001 Tgd 101055 C G chr20:101055:C:G 217125 0.8873225821760312 0.9285446566081813 -0.14291528696175226 0.3239073099184954 +20 ENSG0000010001 Tgd 106954 T C chr20:106954:T:C 142911 0.4062591594129257 0.7871303656570132 -0.8561170433833729 0.35883225499742527 +20 ENSG0000010001 Tgd 107141 C A chr20:107141:C:A 141075 0.4033025535985806 0.5293884172950071 -0.14646415058399986 0.9354299369819692 +20 ENSG0000010001 Tgd 100131 A T chr20:100131:A:T -131990 0.7363979704999686 0.8181764944172313 -0.8779488826532627 0.11114702107464204 +20 ENSG0000010001 Tgd 103141 C G chr20:103141:C:G 183889 0.6393014055135382 0.17255195172104798 -0.43843628250683087 0.12712644712478813 +20 ENSG0000010001 Tgd 104601 T C chr20:104601:T:C 309808 0.6628185108319102 0.1673929876059096 -0.2368591962723463 0.553743917359196 +20 ENSG0000010001 Tgd 109302 C G chr20:109302:C:G 186719 0.6941578391888342 0.9549176177592028 0.6089287643696124 0.8743704490188108 +20 ENSG0000010001 Tgd 100551 C A chr20:100551:C:A 332185 0.203981274340563 0.9099893368781514 0.10709755130124177 0.07291747855891911 +20 ENSG0000010001 Tgd 105467 T G chr20:105467:T:G 284073 0.24201081972366534 0.794560520955505 0.05396712421077354 0.400844884833528 +20 ENSG0000010001 Tgd 107963 A C chr20:107963:A:C -157854 0.2612146904510678 0.41682886988484247 -0.9684549667678728 0.2458033522530256 +20 ENSG0000010001 Tgd 102528 G A chr20:102528:G:A 144931 0.8905309396789851 0.4845557351096873 -0.4653530280084166 0.7479908524294995 +20 ENSG0000010001 Tgd 106602 T G chr20:106602:T:G -357360 0.04807781896834373 0.3327579479618876 -0.5875797212855858 0.9252536373292444 +20 ENSG0000010001 Tgd 104898 T C chr20:104898:T:C -71376 0.44444748564724523 0.626537374596944 0.36560073723739195 0.8032165450439618 +20 ENSG0000010001 Tgd 105971 A T chr20:105971:A:T -410356 0.8794789305421783 0.9492515724704921 0.9396999526170242 0.7229322084797979 +20 ENSG0000010001 Tgd 103564 T A chr20:103564:T:A 206297 0.49712742458275505 0.34018410648965725 -0.3599488057341793 0.13962098062225778 +20 ENSG0000010001 Tgd 102601 G T chr20:102601:G:T -62970 0.2598216102834352 0.942393039221614 -0.2584389835944034 0.4782148194738207 +20 ENSG0000010001 Tgd 108389 G A chr20:108389:G:A -32534 0.561178666424083 0.7767615305795932 -0.9552483136774672 0.4810171518870135 +20 ENSG0000010001 Tgd 105627 A G chr20:105627:A:G 6750 0.37464429714028 0.06852167958897892 0.14517324682453525 0.6883043961976427 +20 ENSG0000010001 Tgd 104898 A C chr20:104898:A:C 133355 0.7807525408656251 0.3390532151312281 0.3443686530040242 0.430014592727536 +20 ENSG0000010001 Tgd 104516 C G chr20:104516:C:G -214669 0.4399747956167257 0.4343730684407424 -0.2415293040851958 0.3199200461712969 +20 ENSG0000010001 Tgd 100602 G A chr20:100602:G:A -120788 0.32614363955700676 0.7252841935512204 -0.47335203515526403 0.7939977239270122 +20 ENSG0000010001 Tgd 103445 C T chr20:103445:C:T 303036 0.43190937889399716 0.4707506198975645 -0.014741612943282911 0.33694933426353024 +20 ENSG0000010001 Tgd 100881 T C chr20:100881:T:C 407153 0.11255330104957684 0.2105090570445508 0.18748471831996527 0.4671545849357871 +20 ENSG0000010001 Tgd 100835 A C chr20:100835:A:C 174705 0.25226113544660544 0.45485415949529595 -0.5425676291212478 0.28844866913517553 +20 ENSG0000010001 Tgd 104307 T A chr20:104307:T:A 358413 0.8944310520534455 0.2624149448740064 0.07311924522752467 0.13435838315468898 +20 ENSG0000010001 Tgd 105774 C G chr20:105774:C:G 24792 0.33676646948822486 0.254562371252942 -0.5534984418361069 0.27109312864027635 +20 ENSG0000010001 Tgd 107993 C A chr20:107993:C:A -87378 0.5339672366440221 0.8755362156681813 -0.251814879959926 0.2147826790806272 +20 ENSG0000010001 Tgd 105146 T C chr20:105146:T:C -109008 0.34951810950553186 0.017652949944062857 0.5504939805589775 0.7501268205306748 +20 ENSG0000010001 Tgd 105637 G C chr20:105637:G:C 373321 0.4877991256276173 0.927966047090181 -0.8045578948613836 0.40937537736482543 +20 ENSG0000010001 Tgd 100726 T C chr20:100726:T:C 158578 0.6402750396546556 0.7766946494088822 -0.17891075957351532 0.23909782620662104 +20 ENSG0000010001 Tgd 104948 G A chr20:104948:G:A -184816 0.0182428916172237 0.10176199117021756 -0.1991056530644928 0.593310122401224 +20 ENSG0000010001 Tgd 107285 A C chr20:107285:A:C 264971 0.979072529768199 0.6694409667690635 -0.021720428461369012 0.8095481351824875 +20 ENSG0000010001 Tgd 104024 C A chr20:104024:C:A 82977 0.3492994734171363 0.3193417308621528 -0.31990870841303476 0.04269837575169898 +20 ENSG0000010001 Tgd 103552 G C chr20:103552:G:C -109025 0.7138846648229898 0.4024219590207905 -0.7546775868314581 0.026372887334022883 +20 ENSG0000010001 Tgd 109970 G A chr20:109970:G:A -479768 0.07783308222977314 0.34793460827897993 0.35560901509582665 0.6593944349328984 +20 ENSG0000010001 Tgd 100645 A G chr20:100645:A:G 286122 0.03526589229790278 0.3832176138461524 0.14555720672872097 0.6465595567855285 +20 ENSG0000010001 Tgd 109415 A G chr20:109415:A:G 69372 0.4324761606807195 0.5973824424899963 0.8883184869438718 0.3132884832807051 +20 ENSG0000010001 Tgd 101604 G T chr20:101604:G:T -384823 0.7492611169675478 0.3651652453713182 0.6208445844142658 0.23711436939178318 +20 ENSG0000010001 Tgd 109006 G T chr20:109006:G:T -129915 0.9982143655266001 0.7905867131682953 -0.026385918261748964 0.24091260387485025 +20 ENSG0000010001 Tgd 105834 G A chr20:105834:G:A 12805 0.057792920279909454 0.12808712670832434 0.0679569324602316 0.21518434499070446 +20 ENSG0000010001 Tgd 101399 C A chr20:101399:C:A 289872 0.19384992578694038 0.007301346021969968 -0.45579008475599414 0.04808121824262595 +20 ENSG0000010001 Tgd 107670 C T chr20:107670:C:T 16422 0.6352528952789008 0.9755806745177992 -0.5465780283180883 0.40578339314620765 +20 ENSG0000010001 Tgd 103687 C G chr20:103687:C:G 246866 0.7718909138976034 0.5677762211415646 -0.11674112426302563 0.8203634725924916 +20 ENSG0000010001 Tgd 101025 C A chr20:101025:C:A -294462 0.7035936770412617 0.8541541768118154 0.7826090256506288 0.011992882754869018 +20 ENSG0000010001 Tgd 100845 G T chr20:100845:G:T 343676 0.3642052842242971 0.6288903239142366 0.6869618052953097 0.5611591190021142 +20 ENSG0000010001 Tgd 102513 G A chr20:102513:G:A 38618 0.17410628478459578 0.8498007755183066 -0.637050510218985 0.9916709415295649 +20 ENSG0000010001 Tgd 106801 T G chr20:106801:T:G 349113 0.5912974696306568 0.26441654345051935 0.5568075150239362 0.06924122958145257 +20 ENSG0000010001 Tgd 108300 A C chr20:108300:A:C 157061 0.6576748204707448 0.3222713311518519 -0.6818666040136814 0.3782331775764059 +20 ENSG0000010001 Tgd 101773 G T chr20:101773:G:T 383846 0.3331466973573861 0.6186962788190458 -0.38773206778892244 0.9767689622675259 +20 ENSG0000010001 Tgd 105218 G C chr20:105218:G:C 159739 0.6291154941383629 0.3775423907839771 -0.2553969368328681 0.215555369471629 +20 ENSG0000010001 Tgd 106141 C A chr20:106141:C:A -385312 0.5207719065066854 0.7972926033471927 0.3750651111054937 0.6660669851686931 +20 ENSG0000010001 Tgd 105614 A T chr20:105614:A:T -99396 0.921366389469396 0.187580239111255 0.9327422383172854 0.6874622958063281 +20 ENSG0000010001 Tgd 102366 A T chr20:102366:A:T 79460 0.8255294758682543 0.643468242435716 -0.7994654224810493 0.5935189038304342 +20 ENSG0000010001 Tgd 107284 G C chr20:107284:G:C 318227 0.09971699518753463 0.7785943291918109 -0.4410833438939552 0.49715842865527066 +20 ENSG0000010001 Tgd 101316 C G chr20:101316:C:G 203343 0.13457909349957475 0.02790129144578135 -0.8509983828509529 0.6622139720447757 +20 ENSG0000010001 Tgd 103995 A T chr20:103995:A:T -35570 0.16898396269755556 0.20705882393880393 -0.22166524810466304 0.19639947566105284 +20 ENSG0000010001 Tgd 108326 C G chr20:108326:C:G 452041 0.48290459846116507 0.7323145685569193 -0.9788657875152742 0.4223660825173471 +20 ENSG0000010001 Tgd 107917 G A chr20:107917:G:A 69862 0.23723833095639646 0.46503210348797175 -0.7112375685503691 0.6040964263811958 +20 ENSG0000010001 Tgd 100043 G A chr20:100043:G:A 167427 0.41603598136858466 0.9584611288741911 -0.002024693082544937 0.04275484502059956 +20 ENSG0000010001 Tgd 108940 G A chr20:108940:G:A 188673 0.2998043604416998 0.5010038717831 0.6278448190436192 0.22314797141158124 +20 ENSG0000010001 Tgd 103706 T G chr20:103706:T:G 385994 0.29737302403406296 0.32850647565607183 -0.19878863905813393 0.6151435203699046 +20 ENSG0000010001 Tgd 107656 C A chr20:107656:C:A 117424 0.6128743818649243 0.40127803412828567 -0.3541974467348452 0.9063011506199957 +20 ENSG0000010001 Tgd 103780 A G chr20:103780:A:G 322741 0.911722728983854 0.7960846781552111 0.13825573076591424 0.9652908579259752 +20 ENSG0000010001 Tgd 107972 A T chr20:107972:A:T -187139 0.13068838668087923 0.8143507291525875 0.9960980283393361 0.7054623864767458 +20 ENSG0000010001 Tgd 109768 G A chr20:109768:G:A -370624 0.5523113762524077 0.737392938609245 -0.2524726158581192 0.5742943029533416 +20 ENSG0000010001 Tgd 103078 G T chr20:103078:G:T 107730 0.3912598450820659 0.9544846714345712 -0.07525692466986178 0.17597637627830964 +20 ENSG0000010001 Tgd 105442 T A chr20:105442:T:A 127427 0.24896821854722728 0.9013282313791896 0.4572509696863172 0.7811778938752009 +20 ENSG0000010001 Tgd 105586 T G chr20:105586:T:G 334551 0.003447272931007106 0.17423221553177826 -0.15311277551372693 0.735235546412267 +20 ENSG0000010001 Tgd 100411 G C chr20:100411:G:C 331171 0.2763444074571062 0.010464535218213111 0.7296789563155524 0.9281284116274169 +20 ENSG0000010001 Tgd 103800 T C chr20:103800:T:C 71721 0.23079041209820905 0.5034855740335291 -0.4039149553757291 0.6827605189633138 +20 ENSG0000010001 Tgd 101355 A G chr20:101355:A:G -120324 0.4486345219560942 0.8853895053523568 -0.34745715780134456 0.08537656844063071 +20 ENSG0000010001 Tgd 105104 G T chr20:105104:G:T 308964 0.6902676798851671 0.34516115577606665 -0.9480033982383935 0.16376145275436516 +20 ENSG0000010001 Tgd 101336 C A chr20:101336:C:A 451421 0.8078071755555069 0.0884271275292472 0.8217642686229916 0.24529893582469922 +20 ENSG0000010001 Tgd 101422 G A chr20:101422:G:A 476991 0.22054704531188873 0.8080261331674969 0.724645727916033 0.4543419956256918 +20 ENSG0000010001 Tgd 108074 G A chr20:108074:G:A 398650 0.4859324447755431 0.026825697662275827 -0.9346833326607991 0.4113947067098074 +20 ENSG0000010001 Tgd 107404 A C chr20:107404:A:C -422706 0.1295694727722495 0.9100761259560232 0.39729409489016 0.005807899733108592 +20 ENSG0000010001 Tgd 101528 G C chr20:101528:G:C 67143 0.8091513680805195 0.7607661681964427 0.2623935126555057 0.5910060518118695 +20 ENSG0000010001 Tgd 103422 T G chr20:103422:T:G -96105 0.5586155672287019 0.11530331340472522 0.11470500310578213 0.7642000618941754 +20 ENSG0000010001 Tgd 106615 G A chr20:106615:G:A -490154 0.3877737244949886 0.22444068126502636 -0.3508051940539134 0.9542146251827405 +20 ENSG0000010001 Tgd 109620 G T chr20:109620:G:T 383696 0.08002889632472954 0.7625584935577148 0.5206084882666799 0.04556259422316371 +20 ENSG0000010001 Tgd 103700 T C chr20:103700:T:C 108325 0.7912451134636913 0.7484168546551258 0.4451246667697193 0.4517375717386429 +20 ENSG0000010001 Tgd 108190 A C chr20:108190:A:C 234956 0.873245887333296 0.43878912721098795 0.603985625761994 0.8438535981696141 +20 ENSG0000010001 Tgd 108871 A C chr20:108871:A:C -94184 0.01953372252319563 0.3409051809096747 -0.42097984012666445 0.4841650988415845 +20 ENSG0000010001 Tgd 107455 G C chr20:107455:G:C 423913 0.4495749947581986 0.2899300059200146 0.4863594524725272 0.4189092523759534 +20 ENSG0000010001 Tgd 107559 T G chr20:107559:T:G -340931 0.16641939720065257 0.6831234810994208 -0.5798233703368414 0.5074030143582485 +20 ENSG0000010001 Tgd 104397 A T chr20:104397:A:T 108142 0.010416519707851624 0.5074706320302271 0.9132765186619929 0.3808453548170351 +20 ENSG0000010001 Tgd 105716 G A chr20:105716:G:A 383793 0.4338732539039559 0.7235649048546906 0.45782775577096824 0.18281431882267263 +20 ENSG0000010001 Tgd 106681 A T chr20:106681:A:T 44633 0.13221678086733812 0.40976708219787294 0.09572278672989931 0.03473624451585803 +20 ENSG0000010001 Tgd 107256 G C chr20:107256:G:C -8861 0.04088020888618249 0.654254482724671 0.13900614626706842 0.8931870339035174 +20 ENSG0000010001 Tgd 106657 T G chr20:106657:T:G -266356 0.4970024039479781 0.5892595662455083 0.7586834839795409 0.808089192025665 +20 ENSG0000010001 Tgd 107276 A G chr20:107276:A:G 296172 0.23836288592484578 0.35759039314987284 -0.7399671144202555 0.5974768567161526 +20 ENSG0000010001 Tgd 106667 T C chr20:106667:T:C -288486 0.16396345370879972 0.19259236517854683 0.883281495814261 0.2426145253020067 +20 ENSG0000010001 Tgd 102345 G A chr20:102345:G:A 325751 0.40113556991812094 0.7083691126823201 -0.9449400926453104 0.8483157236127618 +20 ENSG0000010001 Tgd 106191 C T chr20:106191:C:T 213085 0.9171302467756428 0.3988266483841245 -0.3124203286414473 0.13138422762258692 +20 ENSG0000010001 Tgd 105588 C T chr20:105588:C:T 127872 0.30552057244139874 0.1365401633519553 -0.3127309196823822 0.4829117997786927 +20 ENSG0000010001 Tgd 100796 A G chr20:100796:A:G 403333 0.9402057846255681 0.25380840548174455 0.7715624992255568 0.55613080476221 +20 ENSG0000010001 Tgd 104707 G C chr20:104707:G:C -242671 0.1066338130567066 0.9618465720017052 0.26350235571627967 0.764904025441091 +20 ENSG0000010001 Tgd 108525 A C chr20:108525:A:C -325183 0.3621099989865959 0.9630855419562623 0.8090285382147517 0.5298778763961723 +20 ENSG0000010001 Tgd 100106 C T chr20:100106:C:T -34363 0.41019708484510053 0.9933578841588147 0.9412459452750115 0.36579835893726576 +20 ENSG0000010001 Tgd 100490 A T chr20:100490:A:T -455915 0.22868488521953456 0.590091734759177 -0.7398772363545925 0.12322094543916967 +20 ENSG0000010001 Tgd 101232 G A chr20:101232:G:A 445778 0.8993335298674555 0.6214320955338987 0.4341636583740558 0.3267024865867381 +20 ENSG0000010001 Tgd 106575 G T chr20:106575:G:T 497636 0.5918665139055688 0.5766897921400751 -0.7365629294522766 0.8112988759614777 +20 ENSG0000010001 Tgd 109272 G T chr20:109272:G:T 464360 0.8855479919865323 0.497063027344515 0.6527327268955265 0.6999681515933005 +20 ENSG0000010001 Tgd 104123 T C chr20:104123:T:C 94945 0.36229307053389803 0.40869183222711936 0.15255450930348258 0.11398718609225415 +20 ENSG0000010001 Tgd 109461 G C chr20:109461:G:C -184990 0.11485526283912573 0.008341969806364036 -0.6106037682258829 0.18356854324311073 +20 ENSG0000010001 Tgd 109122 A G chr20:109122:A:G -495293 0.01938613745705331 0.07858089135277135 -0.9173451039374256 0.5275439764349203 +20 ENSG0000010001 Tgd 105116 C A chr20:105116:C:A -342648 0.9389967025906013 0.14713957668174515 -0.6815782080497963 0.703604995767977 +20 ENSG0000010001 Tgd 100060 A G chr20:100060:A:G -121619 0.2975574461115451 0.9471154382198378 -0.8663535207756037 0.27615135238541255 +20 ENSG0000010001 Tgd 108164 T A chr20:108164:T:A -441748 0.8684437415603247 0.26906013791107186 -0.16989515525686705 0.8745717035159548 +20 ENSG0000010001 Tgd 105236 C T chr20:105236:C:T -74537 0.6809459453861857 0.5711522955247498 -0.4942752826843422 0.17163937388667025 +20 ENSG0000010001 Tgd 100833 T G chr20:100833:T:G -441907 0.4812814558636679 0.908547645561413 -0.31669127505489225 0.7352095744558428 +20 ENSG0000010001 Tgd 103091 T A chr20:103091:T:A 100692 0.9675953341458968 0.5076886113907932 -0.013177467260379716 0.9021847763409447 +20 ENSG0000010001 Tgd 109100 T G chr20:109100:T:G 60892 0.7072178024371276 0.010465699629818359 -0.9020512730535721 0.08883661449375883 +20 ENSG0000010001 Tgd 104254 C G chr20:104254:C:G 123293 0.1535291614317893 0.134582164893567 -0.029146878786723285 0.26862320851374477 +20 ENSG0000010001 Tgd 108709 C A chr20:108709:C:A 151124 0.6342678178869441 0.006967321750922295 -0.27003483408265105 0.7226445108186497 +20 ENSG0000010001 Tgd 109266 G T chr20:109266:G:T -470946 0.6174251670325291 0.350397557568654 0.14291456536495395 0.04717394918977396 +20 ENSG0000010001 Tgd 109214 T C chr20:109214:T:C -367536 0.23827493359777852 0.7050319697662785 0.9390627527997202 0.4505133146117285 +20 ENSG0000010001 Tgd 100062 C T chr20:100062:C:T 290574 0.4766172214261485 0.3404658474439447 -0.6769493282826275 0.9095816984030417 +20 ENSG0000010001 Tgd 105631 G T chr20:105631:G:T 341033 0.604358014806542 0.4436317464953804 -0.4351551741131847 0.1657088080839958 +20 ENSG0000010001 Tgd 100318 G C chr20:100318:G:C 370831 0.9363201518318833 0.3027039296626385 0.7184227870508939 0.9949241038331738 +20 ENSG0000010001 Tgd 105076 T C chr20:105076:T:C 88553 0.8107026850264072 0.826725849794029 0.16564778107472367 0.1592928702912729 +20 ENSG0000010001 Tgd 102135 C A chr20:102135:C:A 42251 0.9256761412725866 0.2377346060656057 -0.8598202589479502 0.3010787827706497 +20 ENSG0000010001 Tgd 109423 T G chr20:109423:T:G 242685 0.789403725125551 0.4800164563346734 0.7637370042725831 0.2586250942779325 +20 ENSG0000010001 Tgd 103134 C T chr20:103134:C:T 160251 0.8833417470947492 0.8599279471062172 0.2452718004097898 0.4629773916555429 +20 ENSG0000010001 Tgd 108117 T G chr20:108117:T:G -120518 0.47655292682586337 0.33755844759943765 -0.18779878686840346 0.711292969000028 +20 ENSG0000010001 Tgd 105037 T A chr20:105037:T:A 375474 0.15669169733958932 0.9157895041358051 -0.9062494968935968 0.8062746497256161 +20 ENSG0000010001 Tgd 104428 A C chr20:104428:A:C -368550 0.29301149003878457 0.5811823745380639 -0.16247664450095956 0.05151409418029883 +20 ENSG0000010001 Tgd 100501 A C chr20:100501:A:C -490056 0.6014074837104642 0.4189502052888402 -0.2913266795437155 0.22882646505835927 +20 ENSG0000010001 Tgd 106803 T C chr20:106803:T:C 421678 0.1677926138454493 0.3819429926166148 0.5584117616564852 0.6941777370159036 +20 ENSG0000010001 Tgd 102268 T C chr20:102268:T:C -225589 0.5938993629350492 0.9228427412588369 -0.5583524642498585 0.7821082309782189 +20 ENSG0000010001 Tgd 103784 C A chr20:103784:C:A 456690 0.10025579988039957 0.3320877488576507 -0.06647804019262193 0.10962445103584599 +20 ENSG0000010001 Tgd 101863 G T chr20:101863:G:T 359404 0.18227911290527843 0.3107391216713389 -0.868332844099035 0.4918509635332346 +20 ENSG0000010001 Tgd 105379 G A chr20:105379:G:A 421490 0.011525479213404743 0.06577533127146473 -0.4682095479089958 0.9184879282620999 +20 ENSG0000010001 Tgd 103650 T C chr20:103650:T:C 140490 0.527488179393503 0.7369617393083675 -0.10324976144541287 0.30686865599021557 +20 ENSG0000010001 Tgd 102588 T C chr20:102588:T:C 146401 0.41725630078011666 0.4154385023682846 0.38707912685423307 0.7877291106595816 +20 ENSG0000010001 Tgd 101351 C T chr20:101351:C:T 404967 0.5951284767678311 0.7896439296663607 -0.6676718230355352 0.7693788732652587 +20 ENSG0000010001 Tgd 102680 C G chr20:102680:C:G 263986 0.7793724256476582 0.40268404278492365 -0.9788044535710505 0.7199832055091081 +20 ENSG0000010001 Tgd 102348 A G chr20:102348:A:G -184784 0.8424268696701721 0.4065792342093115 0.7293305522309399 0.6452762870524256 +20 ENSG0000010001 Tgd 104934 T G chr20:104934:T:G 27683 0.48889051563605324 0.842034688126636 0.4113297957910007 0.31878079084715094 +20 ENSG0000010001 Tgd 100861 C T chr20:100861:C:T 172449 0.2485843012104998 0.4005523519161581 -0.014581373353436566 0.14446464686389462 +20 ENSG0000010001 Tgd 101003 C T chr20:101003:C:T 217131 0.5745685875434093 0.5874820800067836 -0.4456467878898276 0.8538179700955723 +20 ENSG0000010001 Tgd 109666 T C chr20:109666:T:C -317006 0.5133841594219942 0.5579359136068315 -0.5551358262542803 0.4572169276545188 +20 ENSG0000010001 Tgd 104066 A T chr20:104066:A:T -241764 0.01969382117877716 0.4814018922481198 -0.4455316016020341 0.24930355889679648 +20 ENSG0000010001 Tgd 103412 A T chr20:103412:A:T -258825 0.42310059301723657 0.10147086415539563 -0.6425732500474597 0.2938271429419132 +20 ENSG0000010001 Tgd 107794 C A chr20:107794:C:A 164315 0.5700568969453399 0.37430820011256194 0.4291587444980711 0.4591776338750515 +20 ENSG0000010001 Tgd 100901 C A chr20:100901:C:A -160056 0.9158545216368356 0.3997611258044671 -0.7489730082670136 0.8216778865377377 +20 ENSG0000010001 Tgd 105991 G A chr20:105991:G:A 343025 0.5877586152853232 0.9663583432642604 0.26809981461863086 0.6985661560019472 +20 ENSG0000010001 Tgd 104480 G C chr20:104480:G:C -425335 0.07869623298742812 0.6206498232205915 -0.257328513070759 0.3728892764895787 +20 ENSG0000010001 Tgd 101436 T C chr20:101436:T:C -256133 0.510691760486248 0.8126614692478874 0.8827606065022067 0.7709240715530189 +20 ENSG0000010001 Tgd 101235 A T chr20:101235:A:T 362239 0.9772537628766896 0.9737175098503085 -0.30948133910568565 0.022300201288962467 +20 ENSG0000010001 Tgd 103658 A G chr20:103658:A:G -384578 0.33318156519537057 0.4972123865658157 0.5129009383031571 0.3585843743360152 +20 ENSG0000010001 Tgd 101987 T C chr20:101987:T:C -70525 0.2460313664186703 0.8398955522763281 -0.13883344649784868 0.7452355514772743 +20 ENSG0000010001 Tgd 102198 A C chr20:102198:A:C 435096 0.9484850221583168 0.43257526485209563 -0.36811452908183195 0.01024887707923939 +20 ENSG0000010001 Tgd 100013 A C chr20:100013:A:C -456447 0.2891617726820911 0.05473495509022697 0.21422680560316154 0.6598709332423425 +20 ENSG0000010001 Tgd 108208 C G chr20:108208:C:G 124580 0.44539258227183764 0.8772644555370991 -0.3878561230026565 0.6861527803730675 +20 ENSG0000010001 Tgd 106922 C G chr20:106922:C:G 268327 0.09604698307498638 0.0500551591268148 -0.5669019132868094 0.1496506756999089 +20 ENSG0000010001 Tgd 108413 A T chr20:108413:A:T -459877 0.2810475885812095 0.9738112382280172 -0.21852167462641559 0.11546559946602468 +20 ENSG0000010001 Tgd 103983 A G chr20:103983:A:G 32945 0.4731321685591454 0.5356567705710165 -0.29537132250376086 0.5279147807395674 +20 ENSG0000010001 Tgd 105788 G A chr20:105788:G:A -132456 0.6277105065821451 0.6608383625091019 -0.23638109364999282 0.9932677216519377 +20 ENSG0000010001 Tgd 109123 T G chr20:109123:T:G 1883 0.1760972106755182 0.03427483895444505 -0.04166518227388871 0.1569263221086645 +20 ENSG0000010001 Tgd 108000 T A chr20:108000:T:A 259171 0.6383185385429553 0.5539757543225574 0.3464591304773763 0.9436959730680066 +20 ENSG0000010001 Tgd 104758 G T chr20:104758:G:T 162986 0.19315542621986115 0.2107783358671136 -0.16005007501366952 0.018724872325687827 +20 ENSG0000010001 Tgd 108451 T A chr20:108451:T:A 59380 0.2219451073536043 0.7686465263392201 0.2073208904779642 0.9523476889090511 +20 ENSG0000010001 Tgd 108527 C A chr20:108527:C:A 172706 0.2553032438954669 0.9769424817268223 0.21512974126077755 0.20521512934747665 +20 ENSG0000010001 Tgd 107561 A C chr20:107561:A:C -93648 0.48080597269114456 0.564298652375628 0.8876386498627291 0.37953924923634774 +20 ENSG0000010001 Tgd 108440 C A chr20:108440:C:A 410580 0.5611867333771756 0.7628614790098626 0.7864308521297014 0.0849170812857269 +20 ENSG0000010001 Tgd 104987 C G chr20:104987:C:G -452360 0.3510942881467587 0.6076201259762437 -0.2691140797581255 0.4027685187684073 +20 ENSG0000010001 Tgd 104976 T A chr20:104976:T:A 28252 0.04881452706534428 0.6258168045865081 -0.1222089050783357 0.5889827010114912 +20 ENSG0000010001 Tgd 102402 T C chr20:102402:T:C 54965 0.8348944631317619 0.3461011456588077 -0.33744700612989464 0.791216170457856 +20 ENSG0000010001 Tgd 103936 G T chr20:103936:G:T -480677 0.6770068794493591 0.09942166044211487 -0.009741877205478922 0.5576523007046456 +20 ENSG0000010001 Tgd 101774 T G chr20:101774:T:G -387036 0.37117665472009254 0.547505918744851 0.346595393921419 0.013602624768479194 +20 ENSG0000010001 Tgd 101696 T C chr20:101696:T:C 197079 0.05757702245187535 0.9539363486688472 0.9106098386356907 0.29078228929399125 +20 ENSG0000010001 Tgd 105264 T G chr20:105264:T:G -79038 0.631097402112541 0.2369015553625553 0.020003802751159094 0.135969516653914 +20 ENSG0000010001 Tgd 106186 A G chr20:106186:A:G -275023 0.013189592973872122 0.7983339935060916 0.5438782316758997 0.24948191041220544 +20 ENSG0000010001 Tgd 103601 C T chr20:103601:C:T -171931 0.15738848310029507 0.30721340044186496 0.8736768100563497 0.9859298941920874 +20 ENSG0000010001 Tgd 108057 C A chr20:108057:C:A -41057 0.9915897068987701 0.5663935539258562 0.28763598818744085 0.3147778139738683 +20 ENSG0000010001 Tgd 104448 T G chr20:104448:T:G 226859 0.19465142011065995 0.0997760930796634 0.21127088067601996 0.378214518201392 +20 ENSG0000010001 Tgd 102381 C T chr20:102381:C:T -25686 0.7779890993781862 0.6318363800959322 -0.8886264114949469 0.1667676540186059 +20 ENSG0000010001 Tgd 104093 A T chr20:104093:A:T -264643 0.8966395851516937 0.28696996747667314 -0.2554393502735848 0.7438145095231359 +20 ENSG0000010001 Tgd 107400 A T chr20:107400:A:T -123115 0.07881250723671285 0.36896254508686877 0.1277240326490825 0.04443641589015498 +20 ENSG0000010001 Tgd 104300 A T chr20:104300:A:T 309713 0.8620573245498611 0.8825616904215202 -0.9760552594540381 0.07038028355989541 +20 ENSG0000010001 Tgd 106596 G A chr20:106596:G:A 244109 0.5422649666744329 0.11475847549588025 -0.6406143573297578 0.5795356138941842 +20 ENSG0000010001 Tgd 107993 G A chr20:107993:G:A 112057 0.5568738161147935 0.7996573760636221 -0.16743160660717482 0.3270586446776578 +20 ENSG0000010001 Tgd 107761 G C chr20:107761:G:C 369403 0.5516553134494541 0.81201808791987 0.7155547929085522 0.3034433732526603 +20 ENSG0000010001 Tgd 102545 A T chr20:102545:A:T -332154 0.7992447314938979 0.2595216087555863 0.1106427930172571 0.25181104450787906 +20 ENSG0000010001 Tgd 108917 G T chr20:108917:G:T 259365 0.07049659076568748 0.8683063422254432 -0.5305890670117199 0.07773260655182011 +20 ENSG0000010001 Tgd 106013 A T chr20:106013:A:T 488830 0.07367338864205897 0.835573739346024 -0.7802464676886829 0.5334805539960756 +20 ENSG0000010001 Tgd 102499 A C chr20:102499:A:C 326263 0.12152168604942237 0.7622334677616982 0.33907234033574407 0.4093554417147838 +20 ENSG0000010001 Tgd 106279 C G chr20:106279:C:G 475888 0.7825113966163705 0.09251488650856554 0.0027212883213296735 0.8334791672573447 +20 ENSG0000010001 Tgd 102034 A T chr20:102034:A:T 269274 0.3153284180685796 0.9480139939365169 0.9128261604573951 0.6768649404246228 +20 ENSG0000010001 Tgd 102344 C G chr20:102344:C:G -70916 0.560198907198098 0.6690806878884334 -0.5771632449408468 0.06432714732627248 +20 ENSG0000010001 Tgd 100742 T C chr20:100742:T:C -417696 0.2809036902579395 0.1980041470797248 -0.8604789448429842 0.10454095822389023 +20 ENSG0000010001 Tgd 109214 A C chr20:109214:A:C -489821 0.9487773327773319 0.34180602372906965 -0.8281522885351245 0.7041675071584017 +20 ENSG0000010001 Tgd 102566 C A chr20:102566:C:A -33453 0.873874281251776 0.66851646454801 -0.38056453597815154 0.4509855082445878 +20 ENSG0000010001 Tgd 108231 C G chr20:108231:C:G -498571 0.5725246350827824 0.2748904808788366 -0.9044672279555777 0.9993245575564519 +20 ENSG0000010001 Tgd 106331 G A chr20:106331:G:A -189714 0.6605821461791411 0.5033285652009494 0.053134161422850656 0.07013975590288012 +20 ENSG0000010001 Tgd 103243 A C chr20:103243:A:C 348637 0.8072401013500052 0.7629274644734332 -0.22054901314130038 0.3153877820769508 +20 ENSG0000010001 Tgd 102051 T G chr20:102051:T:G -155939 0.6613923607522002 0.47239651977750285 -0.46241359724760844 0.055597996924362625 +20 ENSG0000010001 Tgd 104387 A T chr20:104387:A:T -274772 0.85785143817311 0.9373590979705274 -0.4689507147927401 0.6186186448168771 +20 ENSG0000010001 Tgd 109513 G A chr20:109513:G:A 133621 0.9425681846564299 0.2469322130714252 -0.7869147552845042 0.2295305994137468 +20 ENSG0000010001 Tgd 104734 A T chr20:104734:A:T 355449 0.6300735801795161 0.9634717874263189 -0.8583832531525644 0.8336222215438114 +20 ENSG0000010001 Tgd 100278 C T chr20:100278:C:T 485979 0.06536762940006757 0.645903770301649 -0.9090534396814862 0.48942152563880514 +20 ENSG0000010001 Tgd 106498 T A chr20:106498:T:A 218741 0.8365158888414926 0.081214189728813 0.9929015865000399 0.6029581413093233 +20 ENSG0000010001 Tgd 105445 C G chr20:105445:C:G 325025 0.09462109331595603 0.32211916316940936 -0.2076703900478507 0.38910892172224776 +20 ENSG0000010001 Tgd 104729 C G chr20:104729:C:G -195292 0.950583230860931 0.40000570911079003 0.19889420718421946 0.8769371607144862 +20 ENSG0000010001 Tgd 106203 A G chr20:106203:A:G -487295 0.8981830973150686 0.2464563727772795 0.6162472383159947 0.02632781022965589 +20 ENSG0000010001 Tgd 100878 T G chr20:100878:T:G -171588 0.5741220109720017 0.30994231697558106 -0.6054586200573338 0.20278693027837133 +20 ENSG0000010001 Tgd 100606 G A chr20:100606:G:A -383978 0.9315773538125094 0.0738843712385725 -0.786765820179367 0.7037808032641616 +20 ENSG0000010001 Tgd 106933 C A chr20:106933:C:A -321511 0.9219136394025799 0.2680495253698082 -0.4125506865064652 0.944868363602214 +20 ENSG0000010001 Tgd 105844 C G chr20:105844:C:G -30512 0.27931606193966874 0.23236211563120412 0.33116666468947287 0.5194638619775699 +20 ENSG0000010001 Tgd 109252 G C chr20:109252:G:C -107806 0.9401231867205991 0.22881178980728167 0.9712768064275081 0.48056487713291324 +20 ENSG0000010001 Tgd 100435 C T chr20:100435:C:T 450923 0.0012622987958347265 0.9368004706288224 -0.8891975386274353 0.6175716202187318 +20 ENSG0000010001 Tgd 109596 T G chr20:109596:T:G 156940 0.4042184649403894 0.3479836375597293 0.4386818466472151 0.717915413994763 +20 ENSG0000010001 Tgd 107826 G T chr20:107826:G:T -391194 0.994449611413702 0.2164559137935118 0.1358500252523005 0.3041351411833272 +20 ENSG0000010001 Tgd 107006 T C chr20:107006:T:C 31173 0.4953099319164226 0.7227744173425175 0.8581889110542624 0.19688004723926672 +20 ENSG0000010001 Tgd 109178 C G chr20:109178:C:G 399492 0.32956948853842094 0.6612540054589608 0.6711871716638524 0.1542804096034987 +20 ENSG0000010001 Tgd 107851 A C chr20:107851:A:C 235361 0.07824088626379477 0.9253884699863112 -0.5171479542034929 0.5769304370623636 +20 ENSG0000010001 Tgd 102038 G A chr20:102038:G:A -48671 0.005863594750250001 0.36383752196442365 0.2821678087304256 0.4782132581386037 +20 ENSG0000010001 Tgd 103752 C G chr20:103752:C:G 137036 0.12529539405139045 0.8808363207958535 -0.7571296932014648 0.13711124091343713 +20 ENSG0000010001 Tgd 100402 G T chr20:100402:G:T 479855 0.8769078505858363 0.7501153667492678 -0.2137101694604806 0.40124347354037526 +20 ENSG0000010001 Tgd 109709 G A chr20:109709:G:A -393440 0.9386715091464716 0.6626216544000827 0.25678421029281884 0.3283299552519515 +20 ENSG0000010001 Tgd 107963 A T chr20:107963:A:T 128411 0.717347295860477 0.2505374153063594 -0.7353594530308829 0.6959145988977554 +20 ENSG0000010001 Tgd 101623 T C chr20:101623:T:C -162197 0.12614318433654859 0.8337509919125184 0.2968940892034835 0.32993781024835794 +20 ENSG0000010001 Tgd 102845 G A chr20:102845:G:A -492568 0.047910449406572964 0.0802043585760267 0.9168400287072704 0.8191976865975173 +20 ENSG0000010001 Tgd 100908 A C chr20:100908:A:C -55265 0.0737995834296804 0.07041319345003338 0.17083964436759214 0.19333392997299326 +20 ENSG0000010001 Tgd 104226 C A chr20:104226:C:A -353918 0.9475588283517958 0.8554157110377257 -0.997585355536956 0.6729133614162137 +20 ENSG0000010001 Tgd 109111 C G chr20:109111:C:G 372633 0.5729607241190484 0.05123398277284219 0.3607984287529953 0.9501616863218494 +20 ENSG0000010001 Tgd 109187 T A chr20:109187:T:A -435658 0.26369606454156724 0.26239938683230657 -0.7502621338696744 0.6765927622026132 +20 ENSG0000010001 Tgd 107639 T G chr20:107639:T:G 397663 0.9010446961126403 0.36280061281790654 -0.3659801226163011 0.4195719419951519 +20 ENSG0000010001 Tgd 109928 A T chr20:109928:A:T 421474 0.13970913008593955 0.4106607005992746 0.50130580487268 0.5267430155538603 +20 ENSG0000010001 Tgd 106515 C A chr20:106515:C:A 4042 0.38440648513384534 0.6380749987787985 0.2547569271139427 0.718066234969504 +20 ENSG0000010001 Tgd 100477 G C chr20:100477:G:C 301717 0.11636847026853192 0.6277913781729485 0.21510139463448263 0.4241370029616072 +20 ENSG0000010001 Tgd 103102 C A chr20:103102:C:A -66071 0.8476166983130681 0.43454541470047126 -0.9700989300519058 0.24457439146335855 +20 ENSG0000010001 Tgd 103692 A T chr20:103692:A:T 190580 0.17968486977749198 0.34328940614992365 0.5767879322126397 0.534126663215725 +20 ENSG0000010001 Tgd 106592 G A chr20:106592:G:A -316704 0.3805343053345638 0.6025029587775449 -0.07780925060550348 0.26077668960696737 +20 ENSG0000010001 Tgd 109301 C T chr20:109301:C:T 481763 0.1865000748114386 0.18500909139959099 0.22980148217788776 0.7618487132937144 +20 ENSG0000010001 Tgd 104230 T G chr20:104230:T:G 303989 0.7034746835354418 0.5421285736188759 0.01459124852665683 0.8722360754089264 +20 ENSG0000010001 Tgd 101903 A C chr20:101903:A:C 321196 0.9710932763111804 0.22078644518801693 -0.14782863471651164 0.025283871176800102 +20 ENSG0000010001 Tgd 108516 A C chr20:108516:A:C 89224 0.49968214689867785 0.08517289788209748 -0.3321126354148385 0.7027780319554529 +20 ENSG0000010001 Tgd 109730 A G chr20:109730:A:G 232535 0.8887779278077144 0.7799987456312903 0.06129329620166413 0.9291422255273168 +20 ENSG0000010001 Tgd 100855 T C chr20:100855:T:C 105161 0.0979689485437828 0.1519440562711014 0.4264785905142947 0.2671801955966291 +20 ENSG0000010001 Tgd 106393 T G chr20:106393:T:G -323526 0.11622984269601333 0.17857755635920514 0.4489562655482553 0.39744013969506703 +20 ENSG0000010001 Tgd 100369 T C chr20:100369:T:C 33431 0.296956718507858 0.5351873993598225 -0.9865730378745632 0.6228662730765003 +20 ENSG0000010001 Tgd 105648 T G chr20:105648:T:G 461492 0.7966554728988571 0.1955653622868978 0.6611566746086326 0.976769131454646 +20 ENSG0000010001 Tgd 109485 A T chr20:109485:A:T -232765 0.7198116589444801 0.26943234862528465 -0.8293231863753432 0.06532621269676679 +20 ENSG0000010001 Tgd 103549 A T chr20:103549:A:T 244996 0.5277060525543729 0.14841765136495777 -0.2897072822906843 0.9578839245087137 +20 ENSG0000010001 Tgd 107587 G A chr20:107587:G:A -391567 0.1603126776573648 0.9480746653349026 -0.41667271062309585 0.8503121512696694 +20 ENSG0000010001 Tgd 103364 T A chr20:103364:T:A 335172 0.014413696103099394 0.04296121270577413 -0.2041544920766254 0.2499954678195811 +20 ENSG0000010001 Tgd 108326 C T chr20:108326:C:T 36112 0.46633764522650556 0.9615485884928169 0.6771209368779463 0.17211227295973636 +20 ENSG0000010001 Tgd 101813 A G chr20:101813:A:G 216126 0.716116730285454 0.5247639954292982 -0.8335509125625369 0.6370400255094124 +20 ENSG0000010001 Tgd 103761 G C chr20:103761:G:C 299535 0.9196548558071853 0.5447685670028307 -0.7013082029835582 0.003666705805542243 +20 ENSG0000010001 Tgd 102192 G A chr20:102192:G:A 77150 0.294926666749468 0.5447699835148475 -0.49323140338652705 0.6737445456406875 +20 ENSG0000010001 Tgd 107158 T G chr20:107158:T:G 142852 0.6981870713076141 0.7620324484111619 -0.5813187714035715 0.3961643792533941 +20 ENSG0000010001 Tgd 101085 T C chr20:101085:T:C -129347 0.33201691576372383 0.6844312303466689 -0.9610316303622668 0.9570380627294536 +20 ENSG0000010001 Tgd 101324 G T chr20:101324:G:T -281906 0.6900817010377079 0.012864904178708447 -0.16331683083272974 0.9960364994134382 +20 ENSG0000010001 Tgd 102206 C A chr20:102206:C:A -339001 0.7458222333654294 0.5289471092143192 -0.994358871796885 0.9045101884395649 +20 ENSG0000010001 Tgd 104452 T C chr20:104452:T:C -292916 0.9957646165556955 0.33089402919172184 -0.5905772362006361 0.11561329792164508 +20 ENSG0000010001 Tgd 107123 T A chr20:107123:T:A 406461 0.6061446600545735 0.8712001026834759 0.41892843539111735 0.22189242017152833 +20 ENSG0000010001 Tgd 106915 G C chr20:106915:G:C -490301 0.24872923796133173 0.8581280559408291 -0.4915216956464006 0.2791697230709474 +20 ENSG0000010001 Tgd 104141 G A chr20:104141:G:A -42932 0.3909637128107487 0.5802848597191853 -0.9914316232408937 0.6860884741920897 +20 ENSG0000010001 Tgd 104709 C A chr20:104709:C:A 13594 0.40721678956839213 0.1427012799688192 0.890741682244452 0.8303054087952112 +20 ENSG0000010001 Tgd 102785 A T chr20:102785:A:T -189918 0.09589263885479626 0.35866478835099325 -0.36429773542111565 0.019140267368724467 +20 ENSG0000010001 Tgd 109992 A T chr20:109992:A:T -371897 0.3298962029550765 0.1624286302056035 -0.33716675084117265 0.16063742939705222 +20 ENSG0000010001 Tgd 104007 A C chr20:104007:A:C 27658 0.837453287454308 0.19310653942902445 -0.08794180083391612 0.44560860301051325 +20 ENSG0000010001 Tgd 104984 T C chr20:104984:T:C 465983 0.27101326540239157 0.05726596679275464 0.39887335674216273 0.7133955077510807 +20 ENSG0000010001 Tgd 108142 G T chr20:108142:G:T 484004 0.33986236710959683 0.8703660568323893 -0.6030454099802021 0.36476827227082936 +20 ENSG0000010001 Tgd 101746 C T chr20:101746:C:T 356761 0.32462382554517155 0.5065423599319395 -0.1291961247500184 0.18239538627523058 +20 ENSG0000010001 Tgd 107297 T G chr20:107297:T:G -457662 0.2210490709726216 0.9831740889336332 -0.4472792516421644 0.5879735025440329 +20 ENSG0000010001 Tgd 103899 A C chr20:103899:A:C 452606 0.963840941777411 0.8023416541696305 0.06729352311632075 0.7977331688775964 +20 ENSG0000010001 Tgd 100115 G A chr20:100115:G:A 377416 0.5435685920101883 0.06740696578676009 0.77769379093566 0.8435512596606372 +20 ENSG0000010001 Tgd 102151 T A chr20:102151:T:A -158180 0.7364522277820976 0.3526244354511118 -0.18646966750987382 0.32185399362051786 +20 ENSG0000010001 Tgd 108126 T G chr20:108126:T:G 121191 0.7974809747059045 0.22349967821181893 0.4172823921658122 0.7588375286089398 +20 ENSG0000010001 Tgd 107664 G T chr20:107664:G:T -36371 0.8740490917124906 0.32513849263678707 0.7359641445104586 0.10497584525253897 +20 ENSG0000010001 Tgd 106375 A C chr20:106375:A:C 56381 0.570440139358899 0.9115637089952321 -0.9220482290090302 0.756756130076354 +20 ENSG0000010001 Tgd 105712 A T chr20:105712:A:T -288799 0.37891567281871963 0.5216879069441012 0.5537044759982974 0.06172710599567462 +20 ENSG0000010001 Tgd 108422 T C chr20:108422:T:C -19222 0.4326229593214297 0.7483333354469237 -0.7401905853805093 0.5080797161831274 +20 ENSG0000010001 Tgd 109467 T A chr20:109467:T:A 220223 0.9883893126300105 0.4958420565781241 -0.2191682323440336 0.10672153949538689 +20 ENSG0000010001 Tgd 101915 T G chr20:101915:T:G 105359 0.883856861742586 0.8456407904207263 -0.7467083563425794 0.10602741472250063 +20 ENSG0000010001 Tgd 105380 G A chr20:105380:G:A 456684 0.7831457619093415 0.8489663915360472 -0.5775126588214845 0.6770822045450229 +20 ENSG0000010001 Tgd 108864 C T chr20:108864:C:T 38301 0.3654951209864047 0.6427084353807239 0.8867697054270129 0.8609195006575793 +20 ENSG0000010001 Tgd 108391 G A chr20:108391:G:A 72625 0.772968104235747 0.25820267033533995 -0.5302958642072308 0.575805008016111 +20 ENSG0000010001 Tgd 106487 T A chr20:106487:T:A 246338 0.909367702130564 0.5684728846591183 0.29009975499023244 0.47079370322804676 +20 ENSG0000010001 Tgd 108134 G C chr20:108134:G:C 411787 0.799970897359452 0.27710378252207724 0.699998035475772 0.044171660970505844 +20 ENSG0000010001 Tgd 106603 T G chr20:106603:T:G -357984 0.3856013762969487 0.7711849877704077 -0.31328036956773353 0.6545379592182287 +20 ENSG0000010001 Tgd 104878 G C chr20:104878:G:C 95638 0.10912517226762519 0.3909991981908124 0.8733655184556868 0.7338922425348791 +20 ENSG0000010001 Tgd 104088 C T chr20:104088:C:T 465635 0.611223902670478 0.3293898251265641 0.25334931368873126 0.7109278091218771 +20 ENSG0000010001 Tgd 109302 A G chr20:109302:A:G 351836 0.605970075011572 0.782816026898486 0.9322529052077724 0.36451039356570897 +20 ENSG0000010001 Tgd 105149 G T chr20:105149:G:T 466716 0.6719310916727725 0.3298656673479059 0.3319863078925349 0.7975708419875192 +20 ENSG0000010001 Tgd 101181 C T chr20:101181:C:T -178525 0.6771904978077353 0.488805710084798 0.9104902549598166 0.21130539341071536 +20 ENSG0000010001 Tgd 107256 A G chr20:107256:A:G -11687 0.9573015525037756 0.09391943276048764 0.8424117369366018 0.6371841499508978 +20 ENSG0000010001 Tgd 103168 C A chr20:103168:C:A 173100 0.6264180913762304 0.4919295348812719 0.06920296278464799 0.3885162971264447 +20 ENSG0000010001 Tgd 102568 T C chr20:102568:T:C -203756 0.013654040070595674 0.9041899829290092 -0.18239954737360997 0.5882807295353022 +20 ENSG0000010001 Tgd 105572 T C chr20:105572:T:C 215252 0.7658275369049462 0.7280454128033448 -0.5515833633095271 0.7652143235778692 +20 ENSG0000010001 Tgd 102265 G C chr20:102265:G:C -294933 0.15862201495916206 0.2378928833720234 0.38871150718587266 0.7112242650366093 +20 ENSG0000010001 Tgd 101948 C G chr20:101948:C:G -336554 0.26248170133110527 0.6899719242277004 -0.6232508698157357 0.9686103269147198 +20 ENSG0000010001 Tgd 104026 C G chr20:104026:C:G 10969 0.07483657667055121 0.4238809182659584 0.22474843754975815 0.886343635636169 +20 ENSG0000010001 Tgd 109588 T C chr20:109588:T:C -170786 0.3681444476893282 0.6948607001564246 0.973389088938095 0.042859745750827655 +20 ENSG0000010001 Tgd 102438 G A chr20:102438:G:A -6893 0.25147645230325233 0.19456157399786 0.9487500534827726 0.2662034856161534 +20 ENSG0000010001 Tgd 105906 C G chr20:105906:C:G 338017 0.39162794583407834 0.7659713265308546 -0.784452892079766 0.5641547364520448 +20 ENSG0000010001 Tgd 109783 A T chr20:109783:A:T 809 0.6770008037419546 0.7558247952587569 -0.9714617156574297 0.41905748963060085 +20 ENSG0000010001 Tgd 100487 A T chr20:100487:A:T -322938 0.8693035777615543 0.906351797121946 0.08204076661329585 0.23761844042360053 +20 ENSG0000010001 Tgd 100433 C G chr20:100433:C:G -189580 0.28328339322839924 0.5574572436137101 -0.2945976965377872 0.6715254727033271 +20 ENSG0000010001 Tgd 104206 C A chr20:104206:C:A -367807 0.9695252732030296 0.21224598367283332 -0.33433941857957983 0.007610336804558851 +20 ENSG0000010001 Tgd 108167 G C chr20:108167:G:C 467764 0.7935855181246064 0.23208681230370698 -0.7262030767178742 0.4105325865072598 +20 ENSG0000010001 Tgd 103141 A C chr20:103141:A:C 211326 0.8234805718888336 0.035365648785470105 0.03909717765365861 0.6945866395688685 +20 ENSG0000010001 Tgd 104001 T G chr20:104001:T:G 433014 0.9291309756249625 0.017372006056768363 0.8938919855006324 0.18457780642447622 +20 ENSG0000010001 Tgd 101017 G C chr20:101017:G:C 494991 0.3371586999038948 0.023363779488288383 -0.7916331371976204 0.7734856700665256 +20 ENSG0000010001 Tgd 100609 C A chr20:100609:C:A -318971 0.038672857402391236 0.20720638024820837 0.6966868074057266 0.25359855514786667 +20 ENSG0000010001 Tgd 100544 G T chr20:100544:G:T 456683 0.1145052118777673 0.18232152408447744 -0.8522285885925143 0.649404372613458 +20 ENSG0000010001 Tgd 103894 T A chr20:103894:T:A 276609 0.596268736999864 0.5779914328445851 -0.24415107394461888 0.6491493443011557 +20 ENSG0000010001 Tgd 102404 C T chr20:102404:C:T -473901 0.48038394067466017 0.15961541364592546 0.8392885389611573 0.04308160277475547 +20 ENSG0000010001 Tgd 100912 T G chr20:100912:T:G -33938 0.7485976687053462 0.18183107267342502 0.5588076122722185 0.31624097178716837 +20 ENSG0000010001 Tgd 109170 C G chr20:109170:C:G 271057 0.5414737130362379 0.8891384038694535 0.5785719330089532 0.8907734555077149 +20 ENSG0000010001 Tgd 102381 A G chr20:102381:A:G -297085 0.15072589485927979 0.6929695431905523 0.03710622833065358 0.6940079139213515 +20 ENSG0000010001 Tgd 100423 A T chr20:100423:A:T -58143 0.9760401962468137 0.553406283654391 0.8030735446682016 0.2594275687824287 +20 ENSG0000010001 Tgd 106867 T C chr20:106867:T:C 14923 0.40835187593952516 0.8446425092806532 -0.166088062249518 0.6929177862114733 +20 ENSG0000010001 Tgd 100319 G C chr20:100319:G:C -38668 0.15563149522821962 0.6276271809419216 0.8336317362870218 0.9993244715131716 +20 ENSG0000010001 Tgd 102899 C G chr20:102899:C:G -271915 0.45304856859231213 0.4657764039551977 -0.49878314928302836 0.495323225273993 +20 ENSG0000010001 Tgd 108788 C A chr20:108788:C:A -37034 0.003603524047609441 0.696877954148313 0.2119915824023575 0.41715761575670773 +20 ENSG0000010001 Tgd 107841 A G chr20:107841:A:G -409392 0.1422791995471855 0.614821683719375 0.0002463252345275002 0.4543065131347051 +20 ENSG0000010001 Tgd 102510 C T chr20:102510:C:T -81739 0.5224526752628141 0.7955654233600128 -0.7273382915161624 0.7968522631370647 +20 ENSG0000010001 Tgd 102403 G A chr20:102403:G:A 241808 0.6439011823824752 0.37765517277387906 -0.7609472805627162 0.027818944665107783 +20 ENSG0000010001 Tgd 105597 T G chr20:105597:T:G -421848 0.6454737746413495 0.9415061207431947 -0.9334492186503283 0.3878053676404592 +20 ENSG0000010001 Tgd 106518 A T chr20:106518:A:T -422122 0.6899737033198026 0.9636951285694791 -0.19716140064598786 0.3063087676425091 +20 ENSG0000010001 Tgd 107733 C A chr20:107733:C:A -348644 0.4662121056216456 0.5236967220225047 0.7951339799644153 0.8802371662857084 +20 ENSG0000010001 Tgd 104301 T C chr20:104301:T:C -250206 0.9829816100975918 0.672251333934612 -0.45988608772745976 0.8386164576821822 +20 ENSG0000010001 Tgd 100296 C A chr20:100296:C:A 47670 0.4399920776692261 0.9309620015505796 -0.7630002577411965 0.0021735039163160276 +20 ENSG0000010001 Tgd 108429 A C chr20:108429:A:C -321166 0.039409588869947276 0.46733928210187137 -0.7930788438837062 0.9491036912780946 +20 ENSG0000010001 Tgd 107722 C A chr20:107722:C:A -201176 0.22608886081677226 0.42464882116796 0.09594366817148248 0.3736171020364574 +20 ENSG0000010001 Tgd 107253 T C chr20:107253:T:C -67690 0.08323749653764734 0.05370857065560719 0.9488911191727762 0.09249917163664668 +20 ENSG0000010001 Tgd 109350 G A chr20:109350:G:A 354843 0.10613525283606462 0.5552673543759378 -0.2757586832631076 0.726786248478546 +20 ENSG0000010001 Tgd 100194 C A chr20:100194:C:A -344185 0.34801558155658663 0.2890598816077862 -0.052889285035844 0.6863914856228128 +20 ENSG0000010001 Tgd 103763 T A chr20:103763:T:A -414113 0.011955179197767674 0.6745812607716665 0.24020810278088112 0.8858102493077314 +20 ENSG0000010001 Tgd 105972 G C chr20:105972:G:C 179919 0.4607123931828059 0.6928187657442152 0.3272223451747829 0.9371333092781079 +20 ENSG0000010001 Tgd 103770 G C chr20:103770:G:C 123905 0.8670681249236397 0.9877640936620905 0.4963321880881799 0.2551505186303342 +20 ENSG0000010001 Tgd 102737 C T chr20:102737:C:T -97790 0.6631066104635694 0.6804568962419785 0.5271034649311876 0.25865720670878967 +20 ENSG0000010001 Tgd 102716 A C chr20:102716:A:C -412570 0.4044635391549277 0.11300579718665715 0.5571206170141505 0.21197797982668617 +20 ENSG0000010001 Tgd 104780 A C chr20:104780:A:C -402571 0.9004565916811772 0.9953654869471058 -0.5232890776010461 0.9374944830476918 +20 ENSG0000010001 Tgd 103765 G A chr20:103765:G:A 279660 0.6760596253015816 0.376724070065636 0.8344668001651538 0.8376451822941327 +20 ENSG0000010001 Tgd 105247 C G chr20:105247:C:G 304070 0.08840360349665943 0.795715052320101 -0.39764273764622704 0.6576419068007173 +20 ENSG0000010001 Tgd 105951 C G chr20:105951:C:G 41286 0.5091399332794605 0.27503244782142455 0.17646152693442207 0.03582524805510452 +20 ENSG0000010001 Tgd 100956 T C chr20:100956:T:C 27764 0.40076775231149364 0.2832414637094095 -0.9097344774925642 0.35612927239957826 +20 ENSG0000010001 Tgd 104186 A G chr20:104186:A:G -280744 0.1826573480549235 0.37388536903897385 -0.5130269629159878 0.14621177463263463 +20 ENSG0000010001 Tgd 107232 A C chr20:107232:A:C 339574 0.6929815177738834 0.0708203163903941 0.06846425310202386 0.4109481127839579 +20 ENSG0000010001 Tgd 106952 C T chr20:106952:C:T 358266 0.16594483760278045 0.2427628662956196 0.6535055872332303 0.41263783310850455 +20 ENSG0000010001 Tgd 108194 T A chr20:108194:T:A 358505 0.6590795699802025 0.7232130221608778 -0.6028807364279869 0.2757232694215088 +20 ENSG0000010001 Tgd 108715 G C chr20:108715:G:C -337615 0.34616538596301993 0.9678056385239286 -0.009319831986758453 0.9324950617784369 +20 ENSG0000010001 Tgd 100142 C T chr20:100142:C:T 362596 0.5744463243860128 0.8697391441790071 0.8544605148474822 0.9214671168319372 +20 ENSG0000010001 Tgd 108980 A T chr20:108980:A:T -432642 0.8538651671908509 0.804365413501231 -0.05903926533843884 0.683405878649126 +20 ENSG0000010001 Tgd 109976 C G chr20:109976:C:G -180135 0.3865964487561573 0.2946874139793584 0.16774921488622718 0.9355399146840836 +20 ENSG0000010001 Tgd 101699 G C chr20:101699:G:C 215331 0.47443970282872494 0.7944016894666777 -0.6395245182424178 0.2629882357519141 +20 ENSG0000010001 Tgd 101287 G T chr20:101287:G:T 23277 0.3359490300367426 0.04741929328942429 -0.45715234660897996 0.8008091066398679 +20 ENSG0000010001 Tgd 102965 C G chr20:102965:C:G 295336 0.2949109820013952 0.06927120861113178 -0.4447301625568958 0.11643112625292856 +20 ENSG0000010001 Tgd 102232 T G chr20:102232:T:G 433779 0.9169392213468334 0.6912558177731428 0.9251219868967968 0.435529246939816 +20 ENSG0000010001 Tgd 107434 C A chr20:107434:C:A 232214 0.5814268455564592 0.25116788131651946 0.7916252501189072 0.5164165574625715 +20 ENSG0000010001 Tgd 100446 A T chr20:100446:A:T 381114 0.27880000950015404 0.977453965902223 -0.42731447834333824 0.29531136053084206 +20 ENSG0000010001 Tgd 109897 T G chr20:109897:T:G 253681 0.7883237799188476 0.3494726524287727 -0.7623431098293976 0.8871997819381622 +20 ENSG0000010001 Tgd 105901 T A chr20:105901:T:A 487646 0.8113899563650337 0.028222871253124393 -0.1622288475142737 0.6136758305733715 +20 ENSG0000010001 Tgd 108495 A C chr20:108495:A:C -256662 0.10213810487663266 0.03512321510404093 0.413106026210432 0.45006117270164164 +20 ENSG0000010001 Tgd 104908 A T chr20:104908:A:T 377654 0.43999262869523426 0.6751872686763173 0.6168525499843349 0.913676860510687 +20 ENSG0000010001 Tgd 108062 A G chr20:108062:A:G 166621 0.6487001639749934 0.2842688135672471 -0.08686347496204294 0.8744634274526817 +20 ENSG0000010001 Tgd 106855 T A chr20:106855:T:A 338651 0.8064839698757219 0.13005849440055584 -0.8470041273577971 0.5440627471866456 +20 ENSG0000010001 Tgd 100235 G T chr20:100235:G:T 84686 0.9040788522978874 0.5395862814657102 0.5958925939721773 0.9062645357079634 +20 ENSG0000010001 Tgd 106819 A C chr20:106819:A:C 230809 0.8820044793099736 0.3467168481840408 0.7235321925678411 0.33199783410195877 +20 ENSG0000010001 Tgd 106576 G T chr20:106576:G:T -129183 0.4330084050156433 0.70865087086991 -0.4070964294686188 0.523362451614158 +20 ENSG0000010001 Tgd 100471 C T chr20:100471:C:T -420281 0.9381416303765463 0.9148702000288096 0.04662315107722437 0.5407541916582324 +20 ENSG0000010001 Tgd 107091 A C chr20:107091:A:C 374702 0.9522857339192387 0.2725088923432921 0.17866390827808476 0.7150365266286948 +20 ENSG0000010001 Tgd 108618 C T chr20:108618:C:T 62935 0.5015015295934775 0.15631910408687333 0.3853581076964534 0.5330830458861464 +20 ENSG0000010001 Tgd 104695 G A chr20:104695:G:A -155713 0.15411542389136557 0.2425389072242562 0.33969767719833976 0.8398953457760607 +20 ENSG0000010001 Tgd 102746 G A chr20:102746:G:A 331174 0.7335866000848682 0.8648738426535354 -0.580783639165876 0.16018273766373245 +20 ENSG0000010001 Tgd 100275 T G chr20:100275:T:G 490532 0.3816352823596767 0.43647879347326424 -0.41404020597374425 0.7878603848894793 +20 ENSG0000010001 Tgd 107874 G T chr20:107874:G:T -51760 0.9447410743056128 0.7024234359219839 0.555591945915284 0.18696645065938716 +20 ENSG0000010001 Tgd 102360 A T chr20:102360:A:T -343193 0.006292168094359063 0.9939413660225901 -0.03376575635618262 0.5614770925884708 +20 ENSG0000010001 Tgd 104402 G A chr20:104402:G:A 279490 0.007253158142416893 0.18199670810876845 0.07388794761234485 0.8240551485020098 +20 ENSG0000010001 Tgd 104358 G T chr20:104358:G:T -141258 0.8907074587440701 0.17348425979076187 0.9080796338673542 0.1299362311953277 +20 ENSG0000010001 Tgd 107421 G A chr20:107421:G:A -441349 0.2546895394518349 0.2129655356679624 0.061481078810287304 0.7060131604032757 +20 ENSG0000010001 Tgd 107698 T A chr20:107698:T:A 487253 0.12582711708507777 0.46228217497934665 0.49092812293810173 0.6695248250073884 +20 ENSG0000010001 Tgd 102074 T C chr20:102074:T:C 355443 0.9244677782811712 0.4481622198431259 0.8231995258129416 0.3128602903967842 +20 ENSG0000010001 Tgd 102675 C A chr20:102675:C:A 300380 0.7268208859187262 0.15239299335380918 -0.3156340816952117 0.29106341312329137 +20 ENSG0000010001 Tgd 106727 T G chr20:106727:T:G 435720 0.9155027418066858 0.45815336442916854 -0.9226449684326101 0.10515691439729143 +20 ENSG0000010001 Tgd 106809 G A chr20:106809:G:A -122843 0.7887149720175661 0.4213257852020249 0.5686842778954935 0.2862036781037686 +20 ENSG0000010001 Tgd 107541 T G chr20:107541:T:G 382281 0.7867708056158917 0.8737535427754349 -0.23977272795554772 0.011149044928870637 +20 ENSG0000010001 Tgd 104564 C G chr20:104564:C:G 23722 0.7461108358820088 0.2072290941135012 0.42335099247568553 0.6239760774693831 +20 ENSG0000010001 Tgd 101156 T C chr20:101156:T:C 70806 0.6022876600198036 0.35224927615120294 -0.06951010349363429 0.6897823127304432 +20 ENSG0000010001 Tgd 100476 A G chr20:100476:A:G 434457 0.1616808864411109 0.6773902074617156 -0.47645922094558535 0.313472955816247 +20 ENSG0000010001 Tgd 109713 C T chr20:109713:C:T -57768 0.2745869087560009 0.48818970033958864 -0.9519411081644886 0.5556034088212639 +20 ENSG0000010001 Tgd 105293 T A chr20:105293:T:A -410721 0.12877352494042116 0.7184108052194005 -0.5492221435985771 0.9552599874041535 +20 ENSG0000010001 Tgd 109436 T G chr20:109436:T:G -404457 0.8671451491058378 0.37592120575741483 0.08860349988707372 0.24850336084140728 +20 ENSG0000010001 Tgd 106952 A C chr20:106952:A:C 434378 0.8876153718539657 0.775060683475521 -0.8486072266371412 0.5412972818164892 +20 ENSG0000010001 Tgd 100278 A C chr20:100278:A:C 358374 0.21845966731537914 0.45703429192456235 0.6754103870409194 0.19852943393402767 +20 ENSG0000010001 Tgd 102119 T G chr20:102119:T:G -425680 0.9979844787625233 0.9260021625531584 -0.2683713494516473 0.43206190559558716 +20 ENSG0000010001 Tgd 106031 G C chr20:106031:G:C -129378 0.9607143662470387 0.3406266016389874 -0.3134805916010528 0.5704723246953092 +20 ENSG0000010001 Tgd 106027 A C chr20:106027:A:C -160042 0.8965509284178784 0.2399904928231904 0.2583874074626369 0.13486973653422196 +20 ENSG0000010001 Tgd 101360 G A chr20:101360:G:A -185048 0.5139460739832361 0.8753317064798742 0.9141387766575966 0.2869387578865366 +20 ENSG0000010001 Tgd 101218 T C chr20:101218:T:C 487821 0.1604536748653561 0.31294262506798987 0.4781370886153036 0.663141359060911 +20 ENSG0000010001 Tgd 107425 T A chr20:107425:T:A -86487 0.650111334870272 0.09628069306661347 -0.8657978384158256 0.6295231881741877 +20 ENSG0000010001 Tgd 103031 A C chr20:103031:A:C 372657 0.9076775787343149 0.49142603051212586 0.4210650815941621 0.32034977205685394 +20 ENSG0000010001 Tgd 102221 C G chr20:102221:C:G -287684 0.02572063738771424 0.7306511087314054 0.09385043593490927 0.30088533059597267 +20 ENSG0000010001 Tgd 100929 T C chr20:100929:T:C 216389 0.8582430425433247 0.1723028698824005 0.8743842406803655 0.7859881304827542 +20 ENSG0000010001 Tgd 104662 C A chr20:104662:C:A 272574 0.7022306708460487 0.5827495470663533 0.9973366673723416 0.43707149363546094 +20 ENSG0000010001 Tgd 104745 A C chr20:104745:A:C -405362 0.17602743802381238 0.7165494940321675 0.6454813711595135 0.9012770553808391 +20 ENSG0000010001 Tgd 105927 T C chr20:105927:T:C 1424 0.5716741257681287 0.5829945845021538 -0.8777387632816724 0.027882749267151917 +20 ENSG0000010001 Tgd 107839 C A chr20:107839:C:A -357084 0.8004772507466146 0.6554077881326289 0.8084751241484771 0.3255925725637693 +20 ENSG0000010001 Tgd 106663 T C chr20:106663:T:C 277009 0.963232634439028 0.9773941429944591 -0.4760277598940632 0.5028371704395286 +20 ENSG0000010001 Tgd 106012 G A chr20:106012:G:A -288053 0.2143390744986131 0.767137115341561 0.24682549286492672 0.6922126341516132 +20 ENSG0000010001 Tgd 107565 A T chr20:107565:A:T 17544 0.23921662785376696 0.8193865651519756 -0.7680509274005403 0.11738075228472473 +20 ENSG0000010001 Tgd 100425 T A chr20:100425:T:A 425736 0.695805502740662 0.2038162984140276 -0.8328339905450937 0.22456453299070928 +20 ENSG0000010001 Tgd 101512 A T chr20:101512:A:T 148092 0.5256425138621627 0.6023418534602172 0.11211600221746743 0.6450801398587488 +20 ENSG0000010001 Tgd 101151 A T chr20:101151:A:T -426492 0.6707011477422578 0.19219327212075465 -0.21488982492349118 0.5620262951056136 +20 ENSG0000010001 Tgd 103390 A G chr20:103390:A:G -341032 0.2335045766858409 0.43103813291342197 0.7251552138631836 0.3992936807317066 +20 ENSG0000010001 Tgd 100883 C A chr20:100883:C:A 455550 0.48425312403646215 0.011345184283387377 0.3103892686613654 0.6910909051247534 +20 ENSG0000010001 Tgd 109228 G C chr20:109228:G:C -462498 0.32105944166437117 0.8668077739340997 -0.7759709769609908 0.7224547861720495 +20 ENSG0000010001 Tgd 102604 A T chr20:102604:A:T -214336 0.9526853918955698 0.26349662685717423 -0.26424031809184956 0.02878812918954698 +20 ENSG0000010001 Tgd 108079 A C chr20:108079:A:C 437810 0.5192386319842134 0.7699467419895569 -0.3101152471001243 0.8265499628249009 +20 ENSG0000010001 Tgd 108126 G C chr20:108126:G:C 287616 0.7033557307235605 0.3581059627792703 0.7193266548666177 0.45977105970585197 +20 ENSG0000010001 Tgd 103705 A G chr20:103705:A:G 292621 0.7463861272407142 0.11767190988640441 -0.9478050345890514 0.1966503959333515 +20 ENSG0000010001 Tgd 108151 A C chr20:108151:A:C 307973 0.888812830224831 0.7550431299171775 0.9531074888540103 0.9710734067778732 +20 ENSG0000010001 Tgd 103080 G T chr20:103080:G:T -436638 0.4245255470196707 0.8696463365976259 -0.9545801726927718 0.34602461417923985 +20 ENSG0000010001 Tgd 109954 C G chr20:109954:C:G 458395 0.5971959446568967 0.8372975585449343 -0.20619521443228273 0.6867324393465478 +20 ENSG0000010001 Tgd 104024 T G chr20:104024:T:G -437856 0.029278177716972387 0.10809495107970724 0.36237448928170757 0.5233920372275517 +20 ENSG0000010001 Tgd 100146 A G chr20:100146:A:G 408746 0.9130714987643165 0.2743482638594833 -0.9028876638496959 0.4214353379883083 +20 ENSG0000010001 Tgd 104091 C T chr20:104091:C:T 385396 0.03062080442221038 0.7526361600028039 -0.32470952138971754 0.5349822333644172 +20 ENSG0000010001 Tgd 108044 T G chr20:108044:T:G -148671 0.5997786650971205 0.005204162305068927 0.15553963918816294 0.1873176448568589 +20 ENSG0000010001 Tgd 108596 C T chr20:108596:C:T 219214 0.3738338541270019 0.9455505634670333 0.4853890430085013 0.35671465129441465 +20 ENSG0000010001 Tgd 101845 T A chr20:101845:T:A 437600 0.5761083137602757 0.420830553633891 -0.9521475290677657 0.2155564691083026 +20 ENSG0000010001 Tgd 105093 T G chr20:105093:T:G -295054 0.3963792613002243 0.5625922891586116 0.26981179703039704 0.14622477018009608 +20 ENSG0000010001 Tgd 103941 C T chr20:103941:C:T -68832 0.255336161248205 0.36409222721220424 -0.37759813050485835 0.4216705386689858 +20 ENSG0000010001 Tgd 104481 C A chr20:104481:C:A -88020 0.2308882809511853 0.7667239314938823 -0.73946116807176 0.4009244090300572 +20 ENSG0000010001 Tgd 101731 G C chr20:101731:G:C -138025 0.8902614352752041 0.5750874090363455 -0.038428226118745634 0.03827907389928732 +20 ENSG0000010001 Tgd 104263 A C chr20:104263:A:C -234646 0.7992530769070324 0.36987145572462954 -0.6434747793667 0.11362709663828373 +20 ENSG0000010001 Tgd 105106 T G chr20:105106:T:G 434944 0.0684419577769313 0.41407134040456217 -0.2375816834231803 0.10287549979693304 +20 ENSG0000010001 Tgd 106336 A T chr20:106336:A:T 420073 0.37505210992789273 0.08932596084771316 0.2151436234472084 0.4002689634320677 +20 ENSG0000010001 Tgd 100363 G C chr20:100363:G:C 453959 0.2582043720442797 0.7415184929835538 0.001552462127456744 0.24755178661938804 +20 ENSG0000010001 Tgd 108300 C T chr20:108300:C:T 24111 0.4520770243518415 0.9886386339881826 0.6139095578685785 0.1992061928196082 +20 ENSG0000010001 Tgd 104468 T A chr20:104468:T:A 392576 0.08623302051958315 0.6009736728316624 -0.1726752572725887 0.9794385850915994 +20 ENSG0000010001 Tgd 102494 G T chr20:102494:G:T -268741 0.9686741048295746 0.3764072567214206 0.17408990072573105 0.9071899986549363 +20 ENSG0000010001 Tgd 102060 A G chr20:102060:A:G 279872 0.8722868696072811 0.20765937410726287 0.5956850428935432 0.23252229959178136 +20 ENSG0000010001 Tgd 106024 A C chr20:106024:A:C 378425 0.6791802021189101 0.45098146067169353 0.9596805839239575 0.5858914891890065 +20 ENSG0000010001 Tgd 104238 G C chr20:104238:G:C -465244 0.5435957917086927 0.06963318727147494 -0.1762734829853747 0.6934802260989694 +20 ENSG0000010001 Tgd 104254 A T chr20:104254:A:T -211543 0.8162464911318582 0.6283646542718826 0.12394583630576994 0.1896306178251913 +20 ENSG0000010001 Tgd 107764 G A chr20:107764:G:A -483647 0.6910273538527818 0.17272053517752073 -0.025971637249700086 0.5708420618801479 +20 ENSG0000010001 Tgd 109444 C A chr20:109444:C:A -180310 0.8113010464701232 0.593917786737199 -0.2892010769980693 0.2857987436461719 +20 ENSG0000010001 Tgd 106344 G C chr20:106344:G:C -192051 0.13818817463000754 0.08454351858028464 0.4837575070794389 0.6970025585033234 +20 ENSG0000010001 Tgd 105796 G T chr20:105796:G:T -2293 0.34279494858202386 0.5004897490721375 0.9344581963417058 0.11313374147930073 +20 ENSG0000010001 Tgd 101096 G T chr20:101096:G:T -215939 0.3060329739820754 0.5799582947959303 0.5663118404830425 0.6974205518477437 +20 ENSG0000010001 Tgd 105226 C A chr20:105226:C:A 355758 0.4092993044227272 0.21285858415665326 -0.5440940734250532 0.16314388649269965 +20 ENSG0000010001 Tgd 104563 G A chr20:104563:G:A 220216 0.9555497369432151 0.8522423658235586 -0.8939583735093859 0.4455110635962073 +20 ENSG0000010001 Tgd 107621 A T chr20:107621:A:T 216269 0.7121028052491135 0.28386984494520684 0.31222634520889647 0.449023129743566 +20 ENSG0000010001 Tgd 101228 T A chr20:101228:T:A 398037 0.2705840459015725 0.9990735708041935 0.8929725876437122 0.5667122856336372 +20 ENSG0000010001 Tgd 109166 C A chr20:109166:C:A 232798 0.9210016791014919 0.28841965774990774 0.2510266409160782 0.8911359142770074 +20 ENSG0000010001 Tgd 104018 T G chr20:104018:T:G -322810 0.6745029355203745 0.8096778502454753 0.4258835965275769 0.8595858241765054 +20 ENSG0000010001 Tgd 108060 A T chr20:108060:A:T -449378 0.91830397500486 0.4145560032521213 -0.3485770467168523 0.27464493810069907 +20 ENSG0000010001 Tgd 107477 G A chr20:107477:G:A 368156 0.08278760568537824 0.5176525381234857 -0.7402106987903796 0.7290311006025917 +20 ENSG0000010001 Tgd 101061 G A chr20:101061:G:A 207931 0.8901062572132094 0.7903961136528667 -0.4448095400186731 0.9324276090622794 +20 ENSG0000010001 Tgd 100034 G A chr20:100034:G:A -378372 0.9888455004730959 0.11926026698996561 -0.39860646526478694 0.4019274231235483 +20 ENSG0000010001 Tgd 104172 G A chr20:104172:G:A -391923 0.9993584869990019 0.8562586494150557 -0.5177651187725272 0.7584902637599841 +20 ENSG0000010001 Tgd 107496 T C chr20:107496:T:C 415577 0.91831267244721 0.21288569986536587 0.463338402112321 0.7698481905821192 +20 ENSG0000010001 Tgd 108458 C T chr20:108458:C:T -247110 0.497041679918683 0.7216120188616616 -0.03429459079372443 0.2930994638577721 +20 ENSG0000010001 Tgd 108120 G A chr20:108120:G:A -440750 0.46875618815658593 0.5605095989060112 -0.7580007220428733 0.14788456873071418 +20 ENSG0000010001 Tgd 103970 T C chr20:103970:T:C 476666 0.09480679152029847 0.08654617332640535 0.29960281740238925 0.7711235700500924 +20 ENSG0000010001 Tgd 100505 A G chr20:100505:A:G 198188 0.40586626836608897 0.7280128748679808 -0.7031949081846685 0.4309473616348593 +20 ENSG0000010001 Tgd 103331 T C chr20:103331:T:C -18312 0.06317731298407303 0.3074388608523535 0.5159612868022059 0.6689678385039936 +20 ENSG0000010001 Tgd 102189 A T chr20:102189:A:T 216036 0.9930241684989909 0.47238655395527374 0.6639332288058526 0.7495139681781359 +20 ENSG0000010001 Tgd 100347 G A chr20:100347:G:A 350125 0.24596733963056017 0.5201871229463225 -0.8784585218469836 0.631882137899129 +20 ENSG0000010001 Tgd 106831 G T chr20:106831:G:T -327802 0.03658445551030698 0.8005484554220179 0.5889503918954846 0.7065948294854745 +20 ENSG0000010001 Tgd 109350 T C chr20:109350:T:C 29118 0.271319907857983 0.15455055737783407 0.3904887689883192 0.43575884003353255 +20 ENSG0000010001 Tgd 104989 T G chr20:104989:T:G -135502 0.05926518032269268 0.4747719451669108 -0.42720588038567286 0.8636185035612615 +20 ENSG0000010001 Tgd 105576 G C chr20:105576:G:C -36906 0.1332316728463061 0.4708910762903632 -0.2790987539741139 0.2769004927033368 +20 ENSG0000010001 Tgd 109799 T A chr20:109799:T:A -31551 0.9979356570987343 0.2714462689937046 -0.0467419240266862 0.350674950886435 +20 ENSG0000010001 Tgd 100662 T C chr20:100662:T:C -149939 0.7647141898600525 0.7547960441497374 -0.8779797526314466 0.4380258423983575 +20 ENSG0000010001 Tgd 102942 G T chr20:102942:G:T -438819 0.21670664194976785 0.8451566677033283 -0.2221199622258221 0.9520832197600941 +20 ENSG0000010001 Tgd 104190 C T chr20:104190:C:T 499324 0.9264051345826462 0.9524467769511149 -0.5546388739120649 0.011098992222367557 +20 ENSG0000010001 Tgd 100541 G C chr20:100541:G:C 313233 0.760597855144906 0.7324407799623704 -0.5457994142918081 0.08745483140832075 +20 ENSG0000010001 Tgd 108437 C T chr20:108437:C:T 178739 0.14848552846731944 0.46498430818104786 0.48926328835838584 0.3687278840247503 +20 ENSG0000010001 Tgd 102051 C T chr20:102051:C:T 5610 0.7600563290184507 0.5747558816787204 0.9668888453352924 0.06278692369462366 +20 ENSG0000010001 Tgd 105869 T G chr20:105869:T:G 258466 0.9241495785643844 0.40819463581203763 0.8614071787724795 0.1949284164448604 +20 ENSG0000010001 Tgd 108071 G T chr20:108071:G:T -272355 0.9929094110270736 0.12951847277170814 0.06558042680735188 0.3555974477563417 +20 ENSG0000010001 Tgd 106558 G T chr20:106558:G:T 438695 0.786523139721897 0.8548614741391826 -0.5617677495286995 0.6744952382038322 +20 ENSG0000010001 Tgd 103052 C T chr20:103052:C:T -393038 0.03534504944888961 0.809913093070893 0.43492149519227574 0.8247275798101423 +20 ENSG0000010001 Tgd 100872 A C chr20:100872:A:C -350500 0.6549800202817939 0.2509833047956648 0.7922302340571483 0.20520954946667344 +20 ENSG0000010001 Tgd 107304 A C chr20:107304:A:C -292892 0.19108738923982949 0.8868892026071494 -0.6066941815197497 0.12466574914472905 +20 ENSG0000010001 Tgd 108805 T C chr20:108805:T:C -115032 0.3986236723856429 0.7660435733814999 -0.8350209723728501 0.3606873201878669 +20 ENSG0000010001 Tgd 107977 A C chr20:107977:A:C -12685 0.21912052065050724 0.10102764958472399 0.04752959014396052 0.7111532152300766 +20 ENSG0000010001 Tgd 106090 A G chr20:106090:A:G 495599 0.42096648790960634 0.6587251006487189 0.08070752049330632 0.893751782523589 +20 ENSG0000010001 Tgd 106327 C T chr20:106327:C:T -399485 0.36764908946653896 0.6656877971941849 0.07875872837827114 0.22323540897744784 +20 ENSG0000010001 Tgd 102578 G C chr20:102578:G:C -468420 0.32320883278741397 0.7132884647359669 0.25847796833377656 0.45085190524921404 +20 ENSG0000010001 Tgd 109872 G C chr20:109872:G:C 146699 0.20417821603323483 0.7258277085539212 -0.7344269972119775 0.9920527285973473 +20 ENSG0000010001 Tgd 103497 A T chr20:103497:A:T 132532 0.45681420425779473 0.9101784125506043 -0.06250178942523466 0.9163736630176126 +20 ENSG0000010001 Tgd 108485 A C chr20:108485:A:C -476033 0.2380225074662331 0.09460310335355171 0.01961842736796915 0.757803359658066 +20 ENSG0000010001 Tgd 106892 T C chr20:106892:T:C -487750 0.39612257060342937 0.4344015410315315 0.823018979079144 0.6497010731211609 +20 ENSG0000010001 Tgd 106633 A G chr20:106633:A:G 177623 0.4577426479991823 0.9904669917945886 -0.011575409508479906 0.4715602180177471 +20 ENSG0000010001 Tgd 104880 G T chr20:104880:G:T -350761 0.5595138936011125 0.35837488415955765 0.23127561940292884 0.890686945371199 +20 ENSG0000010001 Tgd 100016 T C chr20:100016:T:C -305806 0.31041954567012464 0.8565162902303245 -0.23773269103621963 0.15355124513849763 +20 ENSG0000010001 Tgd 105329 C G chr20:105329:C:G -246231 0.907544319905375 0.4417662046473949 -0.5882035408502673 0.6769877102881816 +20 ENSG0000010001 Tgd 106794 T C chr20:106794:T:C 144965 0.33681688395853215 0.5964744485097406 -0.9855546474298447 0.5567751209983178 +20 ENSG0000010001 Tgd 105700 G C chr20:105700:G:C -43367 0.778695223201234 0.652918214857587 -0.6032272566186427 0.47046021989844433 +20 ENSG0000010001 Tgd 108414 G T chr20:108414:G:T -467168 0.05357536785019201 0.7383308325124713 -0.8179204163596008 0.6625243998715645 +20 ENSG0000010001 Tgd 106162 C G chr20:106162:C:G 188717 0.7947294746429048 0.20488776057821823 0.4089537535135399 0.18670162929476675 +20 ENSG0000010001 Tgd 103351 C G chr20:103351:C:G -219085 0.5642802656727066 0.5983895210898558 -0.8693762954162878 0.6678642371449286 +20 ENSG0000010001 Tgd 100084 C G chr20:100084:C:G -84418 0.719997472838956 0.7272569687880974 0.49557977083869487 0.20866483823348939 +20 ENSG0000010001 Tgd 102528 G C chr20:102528:G:C -181017 0.9239747506041437 0.44727404991946695 0.5375874721649361 0.886681602399414 +20 ENSG0000010001 Tgd 103240 G C chr20:103240:G:C 143865 0.36306729637161583 0.9394451177074994 -0.8172685729810023 0.9917279541292394 +20 ENSG0000010001 Tgd 100955 A T chr20:100955:A:T 19725 0.09672748981756829 0.41483364472266815 0.8305831244246662 0.7713924393694894 +20 ENSG0000010001 Tgd 105993 G T chr20:105993:G:T 250541 0.27190015776803267 0.43532906443898434 0.14929677300738686 0.3008469114205736 +20 ENSG0000010001 Tgd 108090 G A chr20:108090:G:A 280350 0.7709929033099049 0.8918602462467511 0.42307888456556064 0.1316371772637387 +20 ENSG0000010001 Tgd 109382 A C chr20:109382:A:C -92114 0.4367431651411243 0.9183908476484277 -0.824248544080171 0.1921911034588482 +20 ENSG0000010001 Tgd 108886 C G chr20:108886:C:G -35961 0.09057089383464312 0.5286651545939078 0.5073031714520733 0.5029543962117513 +20 ENSG0000010001 Tgd 107292 C T chr20:107292:C:T 354891 0.2640229788032188 0.043396060215161514 0.6388223082315427 0.5086031221717033 +20 ENSG0000010001 Tgd 103512 A G chr20:103512:A:G -334595 0.7469064468396464 0.05775784067658318 -0.5205126994091451 0.5119924894326418 +20 ENSG0000010001 Tgd 109350 G C chr20:109350:G:C -87615 0.8022150815148642 0.9523018720729655 -0.6692008783635839 0.9304085595687408 +20 ENSG0000010001 Tgd 104886 T C chr20:104886:T:C -236666 0.5283897027798025 0.5948646316675591 -0.6463917792328309 0.11298588200269655 +20 ENSG0000010001 Tgd 101674 C G chr20:101674:C:G -466243 0.822544546687115 0.5044038999965296 -0.8730045854284014 0.521591891872553 +20 ENSG0000010001 Tgd 105085 G C chr20:105085:G:C -99695 0.427166573708443 0.9047103174005071 0.1748109579441095 0.05953963114861853 +20 ENSG0000010001 Tgd 107815 G C chr20:107815:G:C -37268 0.2762046639588166 0.43031261663627096 0.8280122515982227 0.12340314885539078 +20 ENSG0000010001 Tgd 103052 T A chr20:103052:T:A 351957 0.33802921357959304 0.9850129615855123 -0.524520505562059 0.5749783468196671 +20 ENSG0000010001 Tgd 106637 G A chr20:106637:G:A 169488 0.5630289755980731 0.6388305056424026 -0.9151896865989433 0.8287192451089264 +20 ENSG0000010001 Tgd 102010 C T chr20:102010:C:T -274706 0.21667501608138418 0.13102214668014955 0.08761609220480704 0.7149341323033539 +20 ENSG0000010001 Tgd 106572 T C chr20:106572:T:C -169014 0.7492081597471513 0.7664201174870645 -0.9481758152343294 0.5865348297685179 +20 ENSG0000010001 Tgd 107896 T A chr20:107896:T:A -388927 0.9915181538162469 0.884277552598466 -0.8628401728814923 0.8557115997449235 +20 ENSG0000010001 Tgd 105797 G A chr20:105797:G:A 68304 0.09264258229151845 0.37478246211213295 -0.890401968586938 0.7479259341166661 +20 ENSG0000010001 Tgd 101485 C A chr20:101485:C:A -301093 0.9133472919551423 0.6254723130495122 0.44804673453684507 0.03714586297579176 +20 ENSG0000010001 Tgd 105837 C A chr20:105837:C:A 103546 0.09488888585450461 0.8129789586342498 0.621118792788917 0.2233886062315171 +20 ENSG0000010001 Tgd 109444 A G chr20:109444:A:G 333569 0.6602642945383126 0.07680291297306985 -0.9844263563116202 0.012456664021077604 +20 ENSG0000010001 Tgd 105099 T C chr20:105099:T:C -481889 0.49039570181376524 0.911778365835508 -0.7971736252283668 0.4231418831023993 +20 ENSG0000010001 Tgd 102519 T A chr20:102519:T:A 299440 0.19471326678580436 0.5764874916748284 -0.6736132359248328 0.13563436540252835 +20 ENSG0000010001 Tgd 109217 C A chr20:109217:C:A 198063 0.05216212528697606 0.9920262457940261 -0.5736052173674036 0.8729093192036915 +20 ENSG0000010001 Tgd 101197 G T chr20:101197:G:T 251145 0.44896584194069067 0.5409012958921868 -0.2226802945222479 0.10711057945508495 +20 ENSG0000010001 Tgd 102971 G T chr20:102971:G:T 255829 0.03282498307277659 0.22955267069377028 -0.8809088767368001 0.38894136689839576 +20 ENSG0000010001 Tgd 106072 A G chr20:106072:A:G -166552 0.4903866326345073 0.09330240017189328 -0.7796651554423621 0.5548129397570343 +20 ENSG0000010001 Tgd 100788 A T chr20:100788:A:T 405423 0.6681746595386833 0.6450697912269349 -0.5399553198396922 0.6798676554930698 +20 ENSG0000010001 Tgd 109973 A T chr20:109973:A:T -159689 0.3571772320845462 0.8748166393156347 0.015936892762574262 0.4958260312842454 +20 ENSG0000010001 Tgd 102223 A G chr20:102223:A:G 326309 0.15064341739685627 0.11502210639948274 -0.43102212524422834 0.6630872061513572 +20 ENSG0000010001 Tgd 109831 G A chr20:109831:G:A 386904 0.020163870464810274 0.5826764084688776 -0.22619383583566766 0.10862968881539865 +20 ENSG0000010001 Tgd 106629 A C chr20:106629:A:C -123236 0.03084153193071426 0.16327730632613402 -0.869795618340645 0.7547798446335213 +20 ENSG0000010001 Tgd 103558 G A chr20:103558:G:A 44071 0.12244914773813043 0.7860233729637056 0.5519481167676838 0.9414833152841595 +20 ENSG0000010001 Tgd 104180 G A chr20:104180:G:A 419016 0.5411153487970624 0.07537672439062537 0.2223695889050239 0.9071296783022929 +20 ENSG0000010001 Tgd 104206 A T chr20:104206:A:T -213556 0.4248520922953113 0.32568328278967795 -0.43902110210002787 0.8754062785062531 +20 ENSG0000010001 Tgd 100489 G A chr20:100489:G:A 119312 0.680104515042566 0.8496442119792283 -0.33516554789789965 0.9087729860157551 +20 ENSG0000010001 Tgd 108217 A G chr20:108217:A:G 367901 0.1317029348933012 0.9446645487601573 -0.47544857352256376 0.3989763871190413 +20 ENSG0000010001 Tgd 109735 T C chr20:109735:T:C 99259 0.6538612398551522 0.48711157037236974 -0.7166808305920871 0.9828192111023175 +20 ENSG0000010001 Tgd 101281 C T chr20:101281:C:T 197466 0.6186627645635996 0.016076201873688967 0.24059606133530598 0.4548465864731579 +20 ENSG0000010001 Tgd 107260 G T chr20:107260:G:T -168445 0.8479719995747103 0.6744829249463655 0.25420150955995946 0.2883671135655434 +20 ENSG0000010001 Tgd 106656 G A chr20:106656:G:A 420793 0.6005702227832533 0.345396490359687 -0.9102075383703976 0.3913553700612241 +20 ENSG0000010001 Tgd 104681 G T chr20:104681:G:T 49911 0.9804100292177107 0.4008542233963518 -0.06117355839567651 0.29419962630140606 +20 ENSG0000010001 Tgd 106150 C A chr20:106150:C:A -358704 0.9660870193117704 0.9619300044058378 -0.2251589875001132 0.6091415617676932 +20 ENSG0000010001 Tgd 107308 G A chr20:107308:G:A -373165 0.7585549681650823 0.38694623214830115 0.5374560910338215 0.5406031409101074 +20 ENSG0000010001 Tgd 107134 A T chr20:107134:A:T -176576 0.5967641139186426 0.1274747123574339 0.6158273807351153 0.40062060761640317 +20 ENSG0000010001 Tgd 108985 G C chr20:108985:G:C -103137 0.1574013146697516 0.49763665159055226 -0.017857137001752177 0.6841319637228327 +20 ENSG0000010001 Tgd 100735 T A chr20:100735:T:A 440411 0.3639229224760817 0.9347567446324254 0.9036910255571733 0.2070754554022118 +20 ENSG0000010001 Tgd 102417 C T chr20:102417:C:T -213198 0.17931143165397612 0.20307906970532807 -0.6972568878297347 0.8279759402053714 +20 ENSG0000010001 Tgd 106395 G A chr20:106395:G:A -25398 0.17975280514359837 0.3619655367418374 0.6984497615183194 0.3401397196497167 +20 ENSG0000010001 Tgd 102461 A C chr20:102461:A:C 452309 0.7321509636722063 0.22766182072801844 -0.6015637998649173 0.08856896194986544 +20 ENSG0000010001 Tgd 101951 G A chr20:101951:G:A -154613 0.6126195561936492 0.8293210314488133 -0.5401289271093161 0.6642177640740888 +20 ENSG0000010001 Tgd 103969 A T chr20:103969:A:T 466112 0.8781807018716054 0.270867451402673 -0.48371380732795766 0.7444261171593857 +20 ENSG0000010001 Tgd 101786 C A chr20:101786:C:A -205311 0.8621195929569665 0.8074455403040879 0.07649691292998084 0.7902280746399762 +20 ENSG0000010001 Tgd 108389 T C chr20:108389:T:C 228410 0.9069337755468391 0.858119161403436 0.36182784799978585 0.6355399595954321 +20 ENSG0000010001 Tgd 107893 T C chr20:107893:T:C -452676 0.7563249479874037 0.09666886872030989 -0.770485499097644 0.9306295335097072 +20 ENSG0000010001 Tgd 102413 T A chr20:102413:T:A -272448 0.492086213996327 0.9403223959047312 0.7309877526977022 0.9013001045740764 +20 ENSG0000010001 Tgd 108472 G T chr20:108472:G:T 403364 0.3107322690086428 0.9734240800768129 -0.3123927266392186 0.4637009457707328 +20 ENSG0000010001 Tgd 107131 T C chr20:107131:T:C -120812 0.5039347892513228 0.4516585169166607 -0.43551846181896514 0.944215927847268 +20 ENSG0000010001 Tgd 105683 T G chr20:105683:T:G -276437 0.7672445975413282 0.30050767587325444 0.04535691366121486 0.5336532801059065 +20 ENSG0000010001 Tgd 103202 G T chr20:103202:G:T -170153 0.31081639450362053 0.747852021349068 -0.7434769624561881 0.3226078394680954 +20 ENSG0000010001 Tgd 105357 G T chr20:105357:G:T 80427 0.025242271506180636 0.046062469369954395 -0.5009440146123569 0.3370730354052621 +20 ENSG0000010001 Tgd 103775 T G chr20:103775:T:G -333447 0.0071153490767732475 0.2619957882268782 -0.2065797824738158 0.43571302673452506 +20 ENSG0000010001 Tgd 106208 A T chr20:106208:A:T 66582 0.5459819582839972 0.49514390751144344 -0.3580941899602228 0.6966004162502872 +20 ENSG0000010001 Tgd 108202 G A chr20:108202:G:A 258077 0.6651264811261142 0.055615556432074054 -0.05472392866900666 0.2083995881243269 +20 ENSG0000010001 Tgd 103525 G C chr20:103525:G:C 133525 0.18958219962360667 0.3714177144850461 0.5001308278642285 0.137127861847999 +20 ENSG0000010001 Tgd 102104 G C chr20:102104:G:C 246452 0.898477911506353 0.08219951582643825 0.5807045244380109 0.2640647340837706 +20 ENSG0000010001 Tgd 100063 G A chr20:100063:G:A -209164 0.9219754657607964 0.3554719995136306 0.18176209611376626 0.8673975989662472 +20 ENSG0000010001 Tgd 106258 G C chr20:106258:G:C -215605 0.9315734669919438 0.2135335435653294 0.1903183727815243 0.6127179562922839 +20 ENSG0000010001 Tgd 107846 C T chr20:107846:C:T -261888 0.8186878282058159 0.8871640062080878 0.5709820029233157 0.9329040492435745 +20 ENSG0000010001 Tgd 102698 T C chr20:102698:T:C -262722 0.2944928132111424 0.599755463001507 -0.007331157262674415 0.7391540475765458 +20 ENSG0000010001 Tgd 108893 C G chr20:108893:C:G 157351 0.06881928245471214 0.5306830445192227 0.013176666085724209 0.8380316698153233 +20 ENSG0000010001 Tgd 107802 G A chr20:107802:G:A 494081 0.710554696589524 0.9303857520893062 0.7653013934319286 0.11648801743231471 +20 ENSG0000010001 Tgd 109383 T G chr20:109383:T:G 136490 0.2551269770961283 0.4563445257924864 0.9552612739549831 0.2203709356595136 +20 ENSG0000010001 Tgd 102091 G C chr20:102091:G:C 111709 0.8674854490536169 0.9525780895339329 -0.5786877987625256 0.11840737583501586 +20 ENSG0000010001 Tgd 102743 A G chr20:102743:A:G -485551 0.2898377288167845 0.20673950527431306 -0.7646812203442985 0.3128845774986147 +20 ENSG0000010001 Tgd 108608 T G chr20:108608:T:G 82563 0.46332367740313674 0.45983169579206884 0.4461141654625931 0.49687316561179223 +20 ENSG0000010001 Tgd 100105 G A chr20:100105:G:A -268076 0.40268932569768967 0.4111301068933926 0.9960342344941941 0.7625578656636103 +20 ENSG0000010001 Tgd 106590 T A chr20:106590:T:A 407496 0.967053757466267 0.7874436727720511 0.29003766981908785 0.12793202897013214 +20 ENSG0000010001 Tgd 109520 T G chr20:109520:T:G 407240 0.9583868349878859 0.16503303856224827 0.11119399652087969 0.26232754134979097 +20 ENSG0000010001 Tgd 107215 T G chr20:107215:T:G -225873 0.7083149164203112 0.21549372821075274 -0.5880190551644362 0.850637035340684 +20 ENSG0000010001 Tgd 104905 C G chr20:104905:C:G 97604 0.16609974698914176 0.7604901569834649 0.8002678960903928 0.4014857954418119 +20 ENSG0000010001 Tgd 106506 A C chr20:106506:A:C 69461 0.35231449446482255 0.23161308537796677 -0.636592444741956 0.25312215272917143 +20 ENSG0000010001 Tgd 104336 T C chr20:104336:T:C 46361 0.8113724718019679 0.2771172715595218 0.7565629035184702 0.5628592063969431 +20 ENSG0000010001 Tgd 101843 C G chr20:101843:C:G -131443 0.09807799126222905 0.966871524314495 -0.6373688113935037 0.03006018924746853 +20 ENSG0000010001 Tgd 106371 T G chr20:106371:T:G 84403 0.6822093359257895 0.47383971331374475 0.41504126815463716 0.3076227894243006 +20 ENSG0000010001 Tgd 103695 G C chr20:103695:G:C 156323 0.9496905023532152 0.0948474711415428 0.3785948516543165 0.7268847892784515 +20 ENSG0000010001 Tgd 109493 T A chr20:109493:T:A 152911 0.24674393608898404 0.5738082882367486 -0.605332867482363 0.10529688323561251 +20 ENSG0000010001 Tgd 106720 T G chr20:106720:T:G -147203 0.5762005634348447 0.1772660947506215 -0.2005018076119427 0.4282420604537955 +20 ENSG0000010001 Tgd 108068 C T chr20:108068:C:T -121590 0.7883129981085614 0.4251453285806075 -0.5827627057813238 0.7757823051682845 +20 ENSG0000010001 Tgd 101464 G C chr20:101464:G:C 124547 0.0729737474383727 0.34604600235863636 0.5488595338765618 0.9958805666107122 +20 ENSG0000010001 Tgd 100385 C T chr20:100385:C:T -46645 0.786622855748153 0.8549653152397073 -0.616022777550161 0.6081978086108355 +20 ENSG0000010001 Tgd 100213 A C chr20:100213:A:C 407947 0.02756840760378443 0.09397686328735855 -0.8360049095162179 0.6101797689881621 +20 ENSG0000010001 Tgd 105478 C A chr20:105478:C:A -177230 0.2830588533239713 0.7493837639600757 -0.17460370105773082 0.2518631386972364 +20 ENSG0000010001 Tgd 102561 A C chr20:102561:A:C 113444 0.6037088782546391 0.08703090252381396 0.7280135262924765 0.525049898660259 +20 ENSG0000010001 Tgd 106452 A G chr20:106452:A:G 315097 0.8192727260845211 0.823314154521296 0.6510370889346193 0.7043316979482359 +20 ENSG0000010001 Tgd 100304 C A chr20:100304:C:A -140730 0.9812409274707451 0.481207581044523 0.06063115092337945 0.9222153838853125 +20 ENSG0000010001 Tgd 106250 G T chr20:106250:G:T -94092 0.4520905999951603 0.9778082820517503 0.16806666069603726 0.39500905506352546 +20 ENSG0000010001 Tgd 100739 G T chr20:100739:G:T -46650 0.3055526481846048 0.6746267540264951 -0.8857303058529882 0.5094082937735334 +20 ENSG0000010001 Tgd 106340 G T chr20:106340:G:T 439319 0.26695738666632407 0.36307204977013074 0.9683575402047104 0.10445475601336711 +20 ENSG0000010001 Tgd 105965 C G chr20:105965:C:G 148085 0.19546925393459047 0.768220781359402 -0.02221465905152109 0.00810589756389287 +20 ENSG0000010001 Tgd 101895 A G chr20:101895:A:G 208761 0.49913749997021206 0.6253503919271712 -0.6342254321253682 0.8368563394263208 +20 ENSG0000010001 Tgd 106779 A G chr20:106779:A:G 32651 0.34033171390221195 0.5083861243115714 0.3757198830849042 0.8676162858919061 +20 ENSG0000010001 Tgd 109017 G A chr20:109017:G:A -463370 0.9278973024799502 0.523745487205851 0.3471005351088976 0.47480846029718277 +20 ENSG0000010001 Tgd 105682 C T chr20:105682:C:T 494986 0.6968610876486131 0.19454731786891344 0.7107876153397861 0.2745328492840406 +20 ENSG0000010001 Tgd 108130 A T chr20:108130:A:T -98733 0.2007645603297703 0.49000223275731003 0.6793142332553064 0.6581950607066809 +20 ENSG0000010001 Tgd 105746 G C chr20:105746:G:C 271072 0.33477874486329096 0.444449831961264 0.4828331379182038 0.38562586205006744 +20 ENSG0000010001 Tgd 104249 C G chr20:104249:C:G 280750 0.07830676696353012 0.3535832229402608 0.25671428157610454 0.7385384376598506 +20 ENSG0000010001 Tgd 104507 G C chr20:104507:G:C 405481 0.3197162795646077 0.03607890544013015 0.2770522405163711 0.25393456568192224 +20 ENSG0000010001 Tgd 105973 T G chr20:105973:T:G 19207 0.16965306252625423 0.6474534720596681 0.11831639297269336 0.2736207711662861 +20 ENSG0000010001 Tgd 108589 G C chr20:108589:G:C 421168 0.22699066729607253 0.6237434689603616 -0.33446768108711744 0.027958572095530817 +20 ENSG0000010001 Tgd 107225 A G chr20:107225:A:G 50478 0.007291379381697549 0.22957206913900186 -0.5681756258201354 0.7296677547182461 +20 ENSG0000010001 Tgd 106093 G T chr20:106093:G:T -304410 0.7216155723270965 0.12086562996860328 -0.18583652971929898 0.38039508843154396 +20 ENSG0000010001 Tgd 108600 A C chr20:108600:A:C 350838 0.7808031814483967 0.4747185723588687 -0.08280388699424424 0.05630721194015985 +20 ENSG0000010001 Tgd 104503 A C chr20:104503:A:C -498629 0.7217107182734549 0.38632383360284117 -0.6466441778719745 0.9894457957581978 +20 ENSG0000010001 Tgd 104220 A C chr20:104220:A:C -391620 0.04588956238452779 0.7380945375524426 -0.717695304637979 0.3616031889320072 +20 ENSG0000010001 Tgd 107656 C G chr20:107656:C:G -220578 0.6916569395620352 0.9978044166317778 0.9078337535382133 0.3947015849121304 +20 ENSG0000010001 Tgd 107076 A T chr20:107076:A:T -270980 0.8507645566546299 0.9516433562076879 0.8068579060687484 0.1973694481433469 +20 ENSG0000010001 Tgd 109346 G C chr20:109346:G:C -383127 0.3356743350225335 0.14663660364269893 -0.8926285250676838 0.9549722026001511 +20 ENSG0000010001 Tgd 109431 C A chr20:109431:C:A -444036 0.8771257779656941 0.021148302994960955 0.2565706296150838 0.43677442202624456 +20 ENSG0000010001 Tgd 107913 A C chr20:107913:A:C -379430 0.3917401604282088 0.9767532163690649 -0.475258371354653 0.881271063842046 +20 ENSG0000010001 Tgd 107796 G T chr20:107796:G:T 43549 0.19631229337934375 0.23605900900842303 0.669053584661006 0.4276890847765495 +20 ENSG0000010001 Tgd 104319 C T chr20:104319:C:T 432652 0.32143207227578163 0.8622110236831065 -0.25759043887866095 0.7061086956749401 +20 ENSG0000010001 Tgd 107751 T C chr20:107751:T:C -475960 0.945837086502924 0.9112847696538146 0.3373628818601546 0.7687654754570552 +20 ENSG0000010001 Tgd 103006 G A chr20:103006:G:A -305249 0.760526340211497 0.02899332140534494 -0.19302463739041387 0.5283294944755794 +20 ENSG0000010001 Tgd 105475 A G chr20:105475:A:G -410666 0.6365089256028723 0.9143025182157628 0.08350301802456461 0.9423905467214463 +20 ENSG0000010001 Tgd 102621 G A chr20:102621:G:A 404601 0.21842139638949443 0.10978738313448422 -0.6247935072782003 0.4622590011008087 +20 ENSG0000010001 Tgd 105963 C A chr20:105963:C:A 233880 0.7364193422051662 0.20710141144116734 0.8267509974309872 0.4987311655418179 +20 ENSG0000010001 Tgd 108201 G A chr20:108201:G:A -149287 0.9166664011286465 0.5050242899246621 0.9584225119904841 0.489789541178948 +20 ENSG0000010001 Tgd 101084 A G chr20:101084:A:G 386070 0.6411798921478181 0.11910555427109959 -0.9400750574667773 0.4278884950135708 +20 ENSG0000010001 Tgd 100669 G A chr20:100669:G:A -22826 0.5277102977408836 0.761351835264578 0.36146071024965254 0.30208932007049083 +20 ENSG0000010001 Tgd 108699 C T chr20:108699:C:T 344660 0.010630043059572714 0.2543052100952313 0.6828501190061873 0.3519179272426493 +20 ENSG0000010001 Tgd 103491 G C chr20:103491:G:C 191991 0.28474826879873805 0.6783933863583123 0.7359533651330172 0.87776327148868 +20 ENSG0000010001 Tgd 108423 T A chr20:108423:T:A 408980 0.45168623741031455 0.8691349686620208 0.012100148869426786 0.7920688141178864 +20 ENSG0000010001 Tgd 106390 C T chr20:106390:C:T 275272 0.9482231369816294 0.4280226416323176 0.48841165779914575 0.3262964056832084 +20 ENSG0000010001 Tgd 108235 C A chr20:108235:C:A 77582 0.5619682346209066 0.5725359611287718 -0.3690984994692281 0.7426918854418101 +20 ENSG0000010001 Tgd 103533 A T chr20:103533:A:T -304766 0.9717177571774767 0.03367431805407728 0.25266662072337787 0.37237082958428613 +20 ENSG0000010001 Tgd 100084 C T chr20:100084:C:T -56112 0.6193137811496444 0.7812379081106563 -0.7516041585323638 0.36224143466945513 +20 ENSG0000010001 Tgd 103387 A T chr20:103387:A:T 136539 0.9475810050824032 0.6583964647535282 -0.19558910457644774 0.1966378063017571 +20 ENSG0000010001 Tgd 100350 C G chr20:100350:C:G -130247 0.2647372034866595 0.0032170487826429506 -0.5103496606744586 0.44072672073278485 +20 ENSG0000010001 Tgd 109719 A C chr20:109719:A:C -211455 0.8050942405674617 0.8415877003976805 0.6086211231350982 0.6829347151774786 +20 ENSG0000010001 Tgd 103416 T A chr20:103416:T:A -376819 0.14596949418173577 0.9746838780340215 0.21851592298273137 0.21578683527800865 +20 ENSG0000010001 Tgd 109150 C A chr20:109150:C:A -476941 0.2922062138320717 0.20047791360606304 0.328602492025059 0.532168360754039 +20 ENSG0000010001 Tgd 100639 G T chr20:100639:G:T 346984 0.9085656259616204 0.30095644688863676 0.7489725816912334 0.7819803959162915 +20 ENSG0000010001 Tgd 100534 T A chr20:100534:T:A 453725 0.9607361357405048 0.2973217258653541 -0.42423004345869186 0.448839171389468 +20 ENSG0000010001 Tgd 108458 C G chr20:108458:C:G 293234 0.8245546034381797 0.6000030521085179 0.7699527323927511 0.5873258742581099 +20 ENSG0000010001 Tgd 108609 T C chr20:108609:T:C 371395 0.7166900808327511 0.6380847519629382 -0.3451653087630546 0.5267404409947793 +20 ENSG0000010001 Tgd 101720 C A chr20:101720:C:A 61810 0.15681404237463703 0.1453396518495892 0.3569825319617077 0.7649240676738667 +20 ENSG0000010001 Tgd 102263 G C chr20:102263:G:C 393336 0.13150413026572416 0.3550358106797441 0.9133784040580182 0.5049388322305073 +20 ENSG0000010001 Tgd 103026 A C chr20:103026:A:C 449237 0.3384477838259088 0.04101868155359001 -0.8927247831693257 0.5137887121871826 +20 ENSG0000010001 Tgd 109424 G C chr20:109424:G:C 386011 0.30333139197380676 0.7417412586644885 -0.09303473848580412 0.10421078517684278 +20 ENSG0000010001 Tgd 105548 A C chr20:105548:A:C 37393 0.5544065183529624 0.5852036158699617 -0.7697426544908406 0.7132842816297816 +20 ENSG0000010001 Tgd 105331 A T chr20:105331:A:T 186195 0.25530766165336094 0.40722188138846593 -0.41903835473848794 0.2380897636900289 +20 ENSG0000010001 Tgd 105447 A G chr20:105447:A:G 478087 0.8506737233174838 0.5956597099474135 -0.2777762510378696 0.7840704391743576 +20 ENSG0000010001 Tgd 109853 T C chr20:109853:T:C 402763 0.3326412626229487 0.5107796421483383 0.717605770558164 0.5082818203931722 +20 ENSG0000010001 Tgd 102198 T G chr20:102198:T:G -40054 0.7759641731510712 0.300025079004676 0.5352783178741376 0.4525739658918815 +20 ENSG0000010001 Tgd 108138 G C chr20:108138:G:C -109821 0.5744239156982286 0.17991966284764782 -0.43225631297552636 0.7083313421037383 +20 ENSG0000010001 Tgd 102068 T G chr20:102068:T:G -344408 0.8515258825455461 0.7366607977956133 0.6244678469213893 0.24907111629877215 +20 ENSG0000010001 Tgd 100279 G A chr20:100279:G:A 245217 0.2850227644604879 0.33093393514087277 -0.2716238111280589 0.9832894904607853 +20 ENSG0000010001 Tgd 108969 C G chr20:108969:C:G -15721 0.8963881899800271 0.9220229962440416 0.6909037514420071 0.1064172695200183 +20 ENSG0000010001 Tgd 106986 C G chr20:106986:C:G 191002 0.8454543090505819 0.11741285885898778 -0.340215766966139 0.5865372404662956 +20 ENSG0000010001 Tgd 105629 A T chr20:105629:A:T 314243 0.4504031422058178 0.44675149219861165 0.24813054105993437 0.791443556642538 +20 ENSG0000010001 Tgd 106154 C A chr20:106154:C:A 320236 0.15486463838269238 0.7758081926832348 -0.6939130054292222 0.14837777537748545 +20 ENSG0000010001 Tgd 107909 G C chr20:107909:G:C -293070 0.8052692939546234 0.9419138005601375 0.6340716983052839 0.9484871772532355 +20 ENSG0000010001 Tgd 103309 C A chr20:103309:C:A 20551 0.9064020509190026 0.6369694979423578 -0.9011493763941205 0.33964584199812076 +20 ENSG0000010001 Tgd 105973 C T chr20:105973:C:T 328695 0.28979005182677653 0.3556464062816428 0.9268518438370803 0.8878424423333163 +20 ENSG0000010001 Tgd 105957 G T chr20:105957:G:T -370998 0.42396267497616047 0.5582435872876006 0.9397217134172007 0.21547493173430696 +20 ENSG0000010001 Tgd 106112 G A chr20:106112:G:A 87717 0.8203721849793136 0.6127614554473859 0.5172551722493544 0.30222068794461965 +20 ENSG0000010001 Tgd 109512 G A chr20:109512:G:A -192030 0.20092304110122994 0.4736493534504952 -0.25888641311648963 0.33029934284696016 +20 ENSG0000010001 Tgd 107726 C T chr20:107726:C:T -401969 0.6257472315296327 0.5790851373731466 0.16614190088977798 0.22384446488006465 +20 ENSG0000010001 Tgd 109110 G A chr20:109110:G:A 316249 0.9381294445400131 0.6816495430881274 -0.5148603190430932 0.06949856483609546 +20 ENSG0000010001 Tgd 106886 A C chr20:106886:A:C 177621 0.6792167650494261 0.9795187643766038 -0.9331761394656624 0.3724337415565939 +20 ENSG0000010001 Tgd 109042 T A chr20:109042:T:A -402656 0.10802686489689384 0.8412190169439407 -0.6535769098444213 0.1626016394607077 +20 ENSG0000010001 Tgd 104671 T G chr20:104671:T:G -245203 0.49977422943290706 0.042564907557822496 0.8192941099768718 0.6660237466800369 +20 ENSG0000010001 Tgd 103870 G T chr20:103870:G:T 489475 0.6548832952550273 0.952060722282409 0.1191953648968902 0.6153233149948999 +20 ENSG0000010001 Tgd 108655 G A chr20:108655:G:A 289253 0.7559210092739322 0.7729248289227916 -0.13544616991012282 0.2492173906637986 +20 ENSG0000010001 Tgd 104473 T A chr20:104473:T:A 70087 0.23258561863733562 0.512503621722456 -0.8145899148941906 0.29465223197759355 +20 ENSG0000010001 Tgd 106632 G C chr20:106632:G:C 4086 0.27809407672956055 0.7279307232511942 -0.17394306798347725 0.2755390828801641 +20 ENSG0000010001 Tgd 100492 C G chr20:100492:C:G 179733 0.5588052287260025 0.7664958885626793 0.5299676085480118 0.7618638320595755 +20 ENSG0000010001 Tgd 109819 T G chr20:109819:T:G 122731 0.78489558138851 0.32726175724180906 -0.8141512619987226 0.6933635011398528 +20 ENSG0000010001 Tgd 107773 G C chr20:107773:G:C -214131 0.609383922565567 0.16876473509594858 -0.22365926911719858 0.44641831900244694 +20 ENSG0000010001 Tgd 101447 G T chr20:101447:G:T 331698 0.5690366522714831 0.703138167671557 -0.5013572410963258 0.8105632777862952 +20 ENSG0000010001 Tgd 105412 C T chr20:105412:C:T -294496 0.6150500273641105 0.01023691104015989 -0.694807371100705 0.37947582085763293 +20 ENSG0000010001 Tgd 109558 A G chr20:109558:A:G -218700 0.7656724151607643 0.5891499101266335 -0.2190542754784306 0.6680042543635046 +20 ENSG0000010001 Tgd 108510 T C chr20:108510:T:C -97653 0.5601849369007746 0.13737090070351066 0.8066318191953379 0.2273298599440059 +20 ENSG0000010001 Tgd 103405 T G chr20:103405:T:G 241345 0.5579971505220079 0.26984141806687223 0.9624969271839576 0.6758144253387024 +20 ENSG0000010001 Tgd 101054 T G chr20:101054:T:G 15836 0.9199175186514976 0.7068440979961356 0.9787173795823245 0.963697579744869 +20 ENSG0000010001 Tgd 108123 T A chr20:108123:T:A 473332 0.26549535086172504 0.3297023797620683 0.16824330963257195 0.6867995927205894 +20 ENSG0000010001 Tgd 105334 C G chr20:105334:C:G 26821 0.3853730228664164 0.6770013719955754 -0.8917765336231533 0.3532091679497571 +20 ENSG0000010001 Tgd 101100 T G chr20:101100:T:G 168154 0.7486109024210088 0.651658538165309 -0.4777234548457323 0.2561928107119985 +20 ENSG0000010001 Tgd 109858 C T chr20:109858:C:T -65648 0.9154884459390593 0.16560881932744487 -0.9271580671124899 0.41167576381760485 +20 ENSG0000010001 Tgd 104184 G C chr20:104184:G:C -297748 0.8828103337534545 0.7996361200004429 -0.6448568099392809 0.06239029843768099 +20 ENSG0000010001 Tgd 102473 A G chr20:102473:A:G -35401 0.2500600029223642 0.7153588615339397 0.7309177423813737 0.1381507537488525 +20 ENSG0000010001 Tgd 104089 C A chr20:104089:C:A 162251 0.5744388706437369 0.5716491637454282 0.05536258738639144 0.6709991983034642 +20 ENSG0000010001 Tgd 100356 C G chr20:100356:C:G -107764 0.6273495115435251 0.23543243276922476 -0.3668023067843309 0.8523653564511449 +20 ENSG0000010001 Tgd 105235 C T chr20:105235:C:T 456763 0.18562967205759628 0.18580493859628167 0.1253092512593308 0.8681635590583031 +20 ENSG0000010001 Tgd 107796 G A chr20:107796:G:A 317276 0.2791492054526262 0.20720725658875128 0.09593458616418471 0.0025622713253610875 +20 ENSG0000010001 Tgd 100665 A G chr20:100665:A:G -454683 0.038160319355356576 0.1511012995757881 0.20627772929551513 0.5292161037251649 +20 ENSG0000010001 Tgd 105728 G C chr20:105728:G:C 108571 0.8318834063904155 0.4064291966099254 0.23626917002496084 0.0219086702050163 +20 ENSG0000010001 Tgd 102175 G A chr20:102175:G:A 237453 0.18019032740106555 0.6164213390680896 -0.14157102859493342 0.9575208818238315 +20 ENSG0000010001 Tgd 104751 T C chr20:104751:T:C 447457 0.9801119901523008 0.8216310679446203 -0.9105055583698862 0.9422341349086121 +20 ENSG0000010001 Tgd 100103 C A chr20:100103:C:A -268448 0.04014849236687057 0.07681071021288266 0.19067705796913215 0.15398958441783137 +20 ENSG0000010001 Tgd 102293 A G chr20:102293:A:G 76464 0.5876739804131864 0.28750071182215375 0.6071525653580199 0.2019651194608433 +20 ENSG0000010001 Tgd 107536 A C chr20:107536:A:C -31275 0.23920676832218934 0.8343728121742425 -0.9125456916776522 0.2465832992166423 +20 ENSG0000010001 Tgd 109988 T G chr20:109988:T:G -204298 0.24891074597723717 0.08698859944652937 -0.17246446870289645 0.4118223059776323 +20 ENSG0000010001 Tgd 106524 A T chr20:106524:A:T -267569 0.2012463167436881 0.08644791621214276 -0.17235565233198114 0.3564470411718847 +20 ENSG0000010001 Tgd 108359 A G chr20:108359:A:G 299890 0.14554578252544037 0.4536891603906694 -0.3364862600211487 0.1506413558242127 +20 ENSG0000010001 Tgd 107486 T A chr20:107486:T:A 207214 0.24195428494499993 0.6290566764149601 -0.0538613386841158 0.05838562543563114 +20 ENSG0000010001 Tgd 107450 C A chr20:107450:C:A -491909 0.007703631291235524 0.9601643782574435 0.8068408481527316 0.8456132637049059 +20 ENSG0000010001 Tgd 107154 G A chr20:107154:G:A -53028 0.5790472999419299 0.3192068000313667 0.9138650160434145 0.772828794978015 +20 ENSG0000010001 Tgd 102914 T C chr20:102914:T:C 338271 0.7957407995136329 0.5743496105332885 -0.5407275295221705 0.6965654714340294 +20 ENSG0000010001 Tgd 103791 A C chr20:103791:A:C -214113 0.5297251588245935 0.7340759901908162 0.4017257887076102 0.9683493778766598 +20 ENSG0000010001 Tgd 106859 C G chr20:106859:C:G 357420 0.05606504452515004 0.4423611058420067 -0.40640002208433357 0.14613494580109032 +20 ENSG0000010001 Tgd 101774 T A chr20:101774:T:A -344910 0.27140963209150404 0.39594482394608954 -0.4698665378650302 0.7501262991114875 +20 ENSG0000010001 Tgd 109397 A T chr20:109397:A:T 255755 0.03452127653797832 0.0688239921345859 0.5496300258106823 0.9060127917060886 +20 ENSG0000010001 Tgd 105179 C G chr20:105179:C:G 312320 0.36502472850237033 0.2478130029460075 0.9610424252844989 0.2038796334802285 +20 ENSG0000010001 Tgd 103902 A C chr20:103902:A:C 5407 0.7086682824212763 0.36830450370835255 -0.39468991468090153 0.4659967880163838 +20 ENSG0000010001 Tgd 100868 A C chr20:100868:A:C -374677 0.4056204316844707 0.9908538554873089 -0.5334255032116593 0.929147069808277 +20 ENSG0000010001 Tgd 100541 T A chr20:100541:T:A 324484 0.462422102769643 0.8284543526668616 0.4933818171852007 0.4413952958988113 +20 ENSG0000010001 Tgd 101824 T C chr20:101824:T:C 237949 0.7000710358755583 0.6223990706325843 0.1035987123626867 0.6802815398189392 +20 ENSG0000010001 Tgd 103670 T G chr20:103670:T:G -402971 0.44908079983252136 0.8405676249179977 0.07815370521116272 0.3813015591476629 +20 ENSG0000010001 Tgd 101777 G C chr20:101777:G:C -461402 0.3546059698187296 0.09439374874219808 0.903679486207615 0.23751792327243468 +20 ENSG0000010001 Tgd 109221 T A chr20:109221:T:A 300560 0.7014449020414752 0.9810317237466967 0.3712624959224653 0.7213877551087781 +20 ENSG0000010001 Tgd 109662 A G chr20:109662:A:G 136040 0.7690780725195723 0.18920449351779156 0.4349489010939007 0.07456243001399904 +20 ENSG0000010001 Tgd 109648 T G chr20:109648:T:G -198511 0.6435831524399492 0.02792986124107366 0.20431632866543126 0.816804780933576 +20 ENSG0000010001 Tgd 104915 A G chr20:104915:A:G -132595 0.7042073586387594 0.8014333593061599 -0.407969431160742 0.9927734715435151 +20 ENSG0000010001 Tgd 105816 T C chr20:105816:T:C 98667 0.2026318530097284 0.8409368870303655 -0.0658308562419676 0.6642828866091781 +20 ENSG0000010001 Tgd 106262 C A chr20:106262:C:A 104555 0.26095973247258064 0.1799266030590867 -0.9753000666354024 0.5384466836516223 +20 ENSG0000010001 Tgd 105249 G T chr20:105249:G:T 184251 0.9417920017334684 0.18228780068581374 -0.7786811056589082 0.6619764044281612 +20 ENSG0000010001 Tgd 102624 G A chr20:102624:G:A 297008 0.12867040915931127 0.9323220091327633 0.2631599107034208 0.38364196398741185 +20 ENSG0000010001 Tgd 101063 A G chr20:101063:A:G 37429 0.8607409735404888 0.01996736779439323 -0.7649197574497828 0.9898694654163537 +20 ENSG0000010001 Tgd 103610 G A chr20:103610:G:A 116179 0.6493530651033164 0.5895672684784095 0.6886338825787803 0.00448467857217126 +20 ENSG0000010001 Tgd 109106 A G chr20:109106:A:G -448664 0.04898915344742916 0.196304686327753 -0.7281320020616928 0.6906044136495151 +20 ENSG0000010001 Tgd 102754 A C chr20:102754:A:C 474197 0.8440087944438034 0.6683271502478303 0.38062977081362614 0.462370396558003 +20 ENSG0000010001 Tgd 108044 G A chr20:108044:G:A -411263 0.2775302206801219 0.5886695792089841 -0.7317366794100308 0.3863114776910389 +20 ENSG0000010001 Tgd 102121 C G chr20:102121:C:G 178931 0.6560379324325047 0.7352492183439283 0.8175208628361257 0.3066027745126195 +20 ENSG0000010001 Tgd 100462 T C chr20:100462:T:C 123510 0.3620169787879546 0.6953640416127211 0.12586149105201194 0.11295650250836235 +20 ENSG0000010001 Tgd 109714 A C chr20:109714:A:C 407354 0.8159545652685967 0.8443010979900244 0.9418687552906913 0.3690265268077473 +20 ENSG0000010001 Tgd 103935 G C chr20:103935:G:C 266096 0.5306468291762154 0.6702190608517188 -0.6505839176221815 0.04583889676376566 +20 ENSG0000010001 Tgd 108127 C A chr20:108127:C:A -54968 0.46697559019183776 0.26568382888496445 0.6209471780431184 0.5254162753123737 +20 ENSG0000010001 Tgd 107748 T C chr20:107748:T:C 67636 0.12064766549316586 0.13071770020442353 -0.7739887015511935 0.7272113950039513 +20 ENSG0000010001 Tgd 104295 G C chr20:104295:G:C 23371 0.4511268333137989 0.23875806759160678 0.7266328034535734 0.6146045298246988 +20 ENSG0000010001 Tgd 108799 T C chr20:108799:T:C -94591 0.6044104663930004 0.5902546679204387 0.503451811137732 0.1782663090625202 +20 ENSG0000010001 Tgd 102370 T A chr20:102370:T:A 230887 0.3799661464397518 0.25417270083565824 0.28082405891910023 0.12396562240686372 +20 ENSG0000010001 Tgd 106251 G A chr20:106251:G:A 105375 0.0890467060252822 0.42022869707766464 0.17053625844711084 0.1899599341944459 +20 ENSG0000010001 Tgd 106055 T A chr20:106055:T:A -276772 0.6271136036239696 0.24531568411480975 0.11022610185131687 0.5572545676420092 +20 ENSG0000010001 Tgd 100649 C G chr20:100649:C:G 56132 0.13260468479692622 0.7978423739823974 0.4473959175188438 0.47796386491162424 +20 ENSG0000010001 Tgd 103804 T C chr20:103804:T:C 384057 0.3314828215385677 0.4235256887193466 -0.6566709272077191 0.1366157015757612 +20 ENSG0000010001 Tgd 104535 G C chr20:104535:G:C 3373 0.5041808122686303 0.11373637755436117 0.1170610510951815 0.4038277311272873 +20 ENSG0000010001 Tgd 109655 T C chr20:109655:T:C 282246 0.3683898309038617 0.45205763899354834 0.14117085894278425 0.1660371307048418 +20 ENSG0000010001 Tgd 102090 A G chr20:102090:A:G 176110 0.4600900449654699 0.43150145810579577 0.8113308985933931 0.009066810670663162 +20 ENSG0000010001 Tgd 104003 C G chr20:104003:C:G -108335 0.8364977818581117 0.6441702294973476 -0.889038140829417 0.32633111463092773 +20 ENSG0000010001 Tgd 107903 A G chr20:107903:A:G -184740 0.20384000297012994 0.9146283054764504 0.33863465936881476 0.21247122757515038 +20 ENSG0000010001 Tgd 105231 T C chr20:105231:T:C -240336 0.5029043028130564 0.6956674462295429 -0.8625806765268127 0.3310950269509758 +20 ENSG0000010001 Tgd 105763 A T chr20:105763:A:T 443646 0.968689981545711 0.15792112834873662 0.23780177938452218 0.5160536634296536 +20 ENSG0000010001 Tgd 103082 G C chr20:103082:G:C -27400 0.643652069213529 0.9918113232978087 -0.6270933913877541 0.6121995080957224 +20 ENSG0000010001 Tgd 103229 T A chr20:103229:T:A -73296 0.5358408792135672 0.8899121867625686 0.5819830665083507 0.9765041226503184 +20 ENSG0000010001 Tgd 108534 A G chr20:108534:A:G 100446 0.7590170373937197 0.22782924602933763 0.8454774853469389 0.643573080107225 +20 ENSG0000010001 Tgd 104467 C A chr20:104467:C:A -436621 0.7858493828539097 0.0674588904950133 -0.4003160872175262 0.8582493512429132 +20 ENSG0000010001 Tgd 109716 G C chr20:109716:G:C 152459 0.19295139125591287 0.2784051063768084 0.1690726004578722 0.11561736142562101 +20 ENSG0000010001 Tgd 100023 G A chr20:100023:G:A -275471 0.9593852099450196 0.762660830076953 0.7253194246836909 0.5866374326212295 +20 ENSG0000010001 Tgd 106058 G C chr20:106058:G:C -279656 0.5286693744859564 0.7965745963364627 0.7754778956496855 0.07848633362833193 +20 ENSG0000010001 Tgd 101461 C G chr20:101461:C:G -460591 0.855091118728013 0.2995681573305693 -0.2611374200042844 0.054157417724897385 +20 ENSG0000010001 Tgd 101516 G C chr20:101516:G:C 382442 0.9330211347251347 0.6871161249382164 -0.23130346555446968 0.30258604770405284 +20 ENSG0000010001 Tgd 100054 T A chr20:100054:T:A 370872 0.2305148716396287 0.7090487796862456 0.5860934166518774 0.623360537025973 +20 ENSG0000010001 Tgd 102780 C A chr20:102780:C:A 14002 0.836533515603069 0.08336002939007592 -0.11035267641961477 0.666741574241286 +20 ENSG0000010001 Tgd 103754 C G chr20:103754:C:G -98370 0.9130696435426094 0.9183264892673562 0.6028764936957136 0.9259922164692012 +20 ENSG0000010001 Tgd 104247 G A chr20:104247:G:A 255753 0.6619911272126164 0.41712058373334815 0.5922125546844252 0.2505855137214919 +20 ENSG0000010001 Tgd 109351 G C chr20:109351:G:C -386381 0.3911829083404378 0.3372970233370487 -0.850882749859116 0.6327744519619821 +20 ENSG0000010001 Tgd 101400 T A chr20:101400:T:A 456962 0.17045698438180878 0.29106518352857225 -0.786611877566509 0.33861593696445713 +20 ENSG0000010001 Tgd 101104 G A chr20:101104:G:A 449429 0.6073727632867914 0.4361225608966711 0.32891513153912255 0.08680812832901476 +20 ENSG0000010001 Tgd 105502 C A chr20:105502:C:A -298941 0.2183319231429054 0.19705885227583753 -0.21586849749600212 0.7310884269536682 +20 ENSG0000010001 Tgd 100203 T C chr20:100203:T:C 486053 0.5972822740683275 0.9210232873807627 -0.3425216539980349 0.43166337835748314 +20 ENSG0000010001 Tgd 105235 A G chr20:105235:A:G 178215 0.6126242287375323 0.6669827354938561 0.4540542881703966 0.5492554577981306 +20 ENSG0000010001 Tgd 109271 A C chr20:109271:A:C -313690 0.7377244591936013 0.30401774192339714 -0.6434370700987584 0.08655871116835984 +20 ENSG0000010001 Tgd 109583 C T chr20:109583:C:T 98138 0.5828968279845151 0.6076042746777438 0.007554339064703042 0.29090297795868186 +20 ENSG0000010001 Tgd 104658 T C chr20:104658:T:C 227048 0.7032723605392235 0.901280496844995 0.16216180010975756 0.580907271063895 +20 ENSG0000010001 Tgd 105267 T A chr20:105267:T:A 449763 0.12070628873146017 0.16228994593613544 0.4212047760267361 0.10896456178109623 +20 ENSG0000010001 Tgd 104948 A T chr20:104948:A:T -445851 0.6192798234684117 0.5060887682929792 -0.3945478841388095 0.30791644231530985 +20 ENSG0000010001 Tgd 108245 A T chr20:108245:A:T -14142 0.18661776885014458 0.7992899164546867 -0.750751491676376 0.6624122411251032 +20 ENSG0000010001 Tgd 107489 C A chr20:107489:C:A 457497 0.41634233528503173 0.9565918316923876 0.387697393287187 0.577137407605576 +20 ENSG0000010001 Tgd 105135 T A chr20:105135:T:A 42514 0.31464540870986113 0.13739399029112087 -0.7953179723128092 0.40323951721930884 +20 ENSG0000010001 Tgd 108743 C T chr20:108743:C:T 69528 0.25070565144781887 0.7152654526594725 -0.9752602915873221 0.12625887308570677 +20 ENSG0000010001 Tgd 104126 G T chr20:104126:G:T 488460 0.3930656647429882 0.8336308232074463 0.25946380559647286 0.9990729788510356 +20 ENSG0000010001 Tgd 102591 A T chr20:102591:A:T -171655 0.2468970264292787 0.8350329247677707 0.5151460451058893 0.2538848540244032 +20 ENSG0000010001 Tgd 103961 A G chr20:103961:A:G -2884 0.3848651575270132 0.3109367770907129 -0.7307688948649245 0.9187964096889593 +20 ENSG0000010001 Tgd 100651 G C chr20:100651:G:C -312853 0.7934917084285058 0.8428377485882431 -0.8964819309046246 0.2418608769828639 +20 ENSG0000010001 Tgd 103583 A C chr20:103583:A:C 395980 0.07304257168374984 0.6879225646943915 0.6287510365828324 0.7545731455590449 +20 ENSG0000010001 Tgd 108079 T C chr20:108079:T:C 337055 0.46195203665142437 0.9746259014127341 -0.310669373325865 0.18366402289888495 +20 ENSG0000010001 Tgd 105675 C A chr20:105675:C:A -41911 0.7449413970919162 0.6664264648317363 0.06369906056837293 0.671240968012514 +20 ENSG0000010001 Tgd 109725 T G chr20:109725:T:G 385001 0.43440194988590275 0.7239180650823003 0.5068797127839544 0.7135961367838055 +20 ENSG0000010001 Tgd 109518 C T chr20:109518:C:T -269806 0.5555510942456446 0.1033980608354349 0.10266389204948356 0.7952405347524415 +20 ENSG0000010001 Tgd 108377 T G chr20:108377:T:G 179586 0.1917039153743263 0.670617726643073 -0.6671759072383301 0.8343650613573237 +20 ENSG0000010001 Tgd 109000 G A chr20:109000:G:A 1328 0.8846391661748206 0.7375937396184662 -0.9205368120342909 0.18146497409092469 +20 ENSG0000010001 Tgd 103806 C G chr20:103806:C:G 310835 0.6504387351198864 0.0790732392748027 0.22839205864198653 0.36784851138468416 +20 ENSG0000010001 Tgd 103855 G T chr20:103855:G:T 207224 0.08087495454252258 0.19116916744968648 -0.5011072112253097 0.7074017870881534 +20 ENSG0000010001 Tgd 100935 C A chr20:100935:C:A 354689 0.46928293990645986 0.8546737953771659 0.31088277702475353 0.49612260948871506 +20 ENSG0000010001 Tgd 106144 A C chr20:106144:A:C 93853 0.28255262716578344 0.5778686747656884 0.2239119379575345 0.9130304302431587 +20 ENSG0000010001 Tgd 103242 C G chr20:103242:C:G -103760 0.5045687736283884 0.704349383400319 -0.17079317383101955 0.7689282524632068 +20 ENSG0000010001 Tgd 103895 A C chr20:103895:A:C 456251 0.5788009938478691 0.07295931585794257 0.5622847053886357 0.25794757782587785 +20 ENSG0000010001 Tgd 104579 C A chr20:104579:C:A -294328 0.817131696984974 0.8244677423605937 0.41596406749738724 0.7427535200646427 +20 ENSG0000010001 Tgd 101103 A G chr20:101103:A:G -281719 0.6594471759257057 0.3543872617910344 0.8414379469701474 0.7042953406268074 +20 ENSG0000010001 Tgd 101631 A G chr20:101631:A:G 22069 0.3086224521892137 0.10725465172919912 -0.5392149690191899 0.8607017533174176 +20 ENSG0000010001 Tgd 107027 T G chr20:107027:T:G 293048 0.35548171947996776 0.6054062248007686 0.8855630733594606 0.33583945099443724 +20 ENSG0000010001 Tgd 100499 C A chr20:100499:C:A 15098 0.23735102636089578 0.8829027855513916 0.8112195453399795 0.14152613272533288 +20 ENSG0000010001 Tgd 104274 T G chr20:104274:T:G 408247 0.7020624837790759 0.8432780839676276 0.5736919315135602 0.4666557370089501 +20 ENSG0000010001 Tgd 100648 T A chr20:100648:T:A -353276 0.5159544876231127 0.4413483147556203 0.7736859737701995 0.8733301228866107 +20 ENSG0000010001 Tgd 109343 T C chr20:109343:T:C 490415 0.8607193925023633 0.6747455406421444 0.48344715955839135 0.8517575296266243 +20 ENSG0000010001 Tgd 105246 T A chr20:105246:T:A -425965 0.9031579431983188 0.4412358161002732 -0.3656524725557746 0.5817628313354289 +20 ENSG0000010001 Tgd 101153 A C chr20:101153:A:C 135778 0.841262697830583 0.2058444934979492 0.9810646621588577 0.1060500512478347 +20 ENSG0000010001 Tgd 100265 G T chr20:100265:G:T -247569 0.05383817714759165 0.4319847578704602 0.5336964478243775 0.7816881285988612 +20 ENSG0000010001 Tgd 109527 C A chr20:109527:C:A -471950 0.2348763928863331 0.9277792165618175 -0.8089504315043787 0.8013653308130334 +20 ENSG0000010001 Tgd 103989 G C chr20:103989:G:C 73719 0.9518350390510486 0.7152633524885739 0.3550204789256233 0.9177775740510811 +20 ENSG0000010001 Tgd 102114 A T chr20:102114:A:T -180655 0.0758027337969982 0.2528270931820249 0.08794672917193003 0.44829162369292697 +20 ENSG0000010001 Tgd 102208 C G chr20:102208:C:G -434275 0.42461186375027404 0.5501527970327591 0.0659176922681195 0.6418879545535745 diff --git a/example_data/dummy_out_ENSG0000010001.tsv.gz b/example_data/dummy_out_ENSG0000010001.tsv.gz index 5dd69ea..24958b1 100644 Binary files a/example_data/dummy_out_ENSG0000010001.tsv.gz and b/example_data/dummy_out_ENSG0000010001.tsv.gz differ diff --git a/example_data/example_data_table_test.csv b/example_data/example_data_table_test.csv new file mode 100644 index 0000000..1126c56 --- /dev/null +++ b/example_data/example_data_table_test.csv @@ -0,0 +1,3 @@ +FILE,CELL,GENE,PHENO_VAR,N +dummy_out_ENSG0000010000.tsv.gz,Tgd,ENSG0000010000,1.5,4000 +dummy_out_ENSG0000010001.tsv.gz,Tgd,ENSG0000010001,1.5,4000 \ No newline at end of file diff --git a/example_data/query_region_list.csv b/example_data/query_region_list.csv new file mode 100644 index 0000000..80cd7df --- /dev/null +++ b/example_data/query_region_list.csv @@ -0,0 +1,3 @@ +CHR,START,END,TRAIT +20,500,9500,Tgd:ENSG0000010000 +20,100000,111000,Tgd:ENSG0000010001 diff --git a/example_data/query_snp_list.csv b/example_data/query_snp_list.csv new file mode 100644 index 0000000..8bea932 --- /dev/null +++ b/example_data/query_snp_list.csv @@ -0,0 +1,8 @@ +CHR,POS,TRAIT +20,1825,Tgd:ENSG0000010000 +20,1425,Tgd:ENSG0000010000 +20,8929,Tgd:ENSG0000010000 +20,6925,Tgd:ENSG0000010000 +20,106793,Tgd:ENSG0000010001 +20,104697,Tgd:ENSG0000010001 +20,107159,Tgd:ENSG0000010001 diff --git a/example_data/recompute_meta_test_table.csv b/example_data/recompute_meta_test_table.csv new file mode 100644 index 0000000..314e9ab --- /dev/null +++ b/example_data/recompute_meta_test_table.csv @@ -0,0 +1,3 @@ +CHR,CELL,GENE,ACAT,MIN_P,N,PHENO_VAR +20,Tgd,ENSG0000010001,0.0,0.0,3000.0,2.5 +20,Tgd,ENSG0000010000,0.0,0.0,3000.0,2.5 diff --git a/example_data/region_list_sc.csv b/example_data/region_list_sc.csv deleted file mode 100644 index 7003d38..0000000 --- a/example_data/region_list_sc.csv +++ /dev/null @@ -1,3 +0,0 @@ -CHR,START,END,TRAIT -20,7121,9121,Tgd:ENSG0000010000 -20,2813,5813,Tgd:ENSG0000010000 diff --git a/example_data/trait_list.csv b/example_data/trait_list.csv deleted file mode 100644 index 8d9626b..0000000 --- a/example_data/trait_list.csv +++ /dev/null @@ -1,2 +0,0 @@ -FILE,N -/nfs/users/nfs_b/ba13/TileDB-sumstat/example_data/dummy_out_ENSG0000010001.tsv.gz,2000 diff --git a/main.nf b/main.nf index ff4ebe9..b2b1e23 100644 --- a/main.nf +++ b/main.nf @@ -35,66 +35,78 @@ workflow { // Pass the TileDB array through all ingestion steps ingestion_results = INGEST_DATA(tiledb_storage, list_files, mapping_file, dummy_file) - // Rest of your workflow... + // Collect all ingestion outputs and merge metadata all_metadata_parts = ingestion_results.metadata_parts.collect() all_ingestion_done = ingestion_results.ingestion_done.collect() updated_tiledb = ingestion_results.tiledb_updated.first() merged_metadata = MERGE_METADATA(updated_tiledb, mapping_file, all_metadata_parts, all_ingestion_done) } + if (params.export){ if (params.snp) { - Channel - .fromPath(params.snp, checkIfExists: true) - .splitCsv(header: true) - .map { row -> - tuple(row.CHR, row) - } - .groupTuple() - .set { tiledb_metadata_batches } - snp_results = EXPORT_SNP(tiledb_metadata_batches) - snp_results.snp_tdb_positions - .transpose() // Convert tuple(chr, [file1, file2]) to [tuple(chr, file1), tuple(chr, file2)] - .collectFile(keepHeader:true) { chr, file -> - ["${params.out}_chr_${chr}_concatenated.csv", file.text] - } - .set { concatenated_files } - - // Optionally publish the concatenated files - concatenated_files.subscribe { file -> - file.copyTo("${params.outdir}/snp_table_concatenated/${file.name}") - } - } + Channel + .fromPath(params.snp, checkIfExists: true) + .splitCsv(header: true) + .map { row -> + tuple(row.CHR, row) + } + .groupTuple() + .set { tiledb_metadata_batches } + snp_results = EXPORT_SNP(tiledb_metadata_batches) + snp_results.snp_tdb_positions + .transpose() + .collectFile(keepHeader:true) { chr, file -> + ["${params.out}_chr_${chr}_concatenated.csv", file.text] + } + .set { concatenated_files } + + concatenated_files.subscribe { file -> + file.copyTo("${params.outdir}/snp_table_concatenated/${file.name}") + } } - if (params.locusbreaker){ - Channel.fromPath(params.table_lb, checkIfExists:true) - .splitText(by: params.tiledb_batch_size, keepHeader: true, file: true) - .map { batch_file -> - def batch_index = (batch_file.name =~ /\.(\d+)\.csv$/)[0][1] - tuple(batch_index, batch_file) - }.set { tiledb_metadata_batches } - - EXPORT_LOCUSBREAKER(tiledb_metadata_batches) - } - if (params.export_traits){ - Channel.fromPath(params.list_traits, checkIfExists:true) + + if (params.regions) { + Channel.fromPath(params.regions, checkIfExists: true) .splitText(by: params.tiledb_batch_size, keepHeader: true, file: true) - .map { batch_file -> - def batch_index = (batch_file.name =~ /\.(\d+)\.csv$/)[0][1] - tuple(batch_index, batch_file) + .map { batch_file -> + def batch_index = (batch_file.name =~ /\.(\d+)\.csv$/)[0][1] + tuple(batch_index, batch_file) }.set { tiledb_metadata_batches } - TRAITS(tiledb_metadata_batches) - + EXPORT_REGIONS(tiledb_metadata_batches) + } } - if (params.recompute_meta){ - Channel.fromPath(params.list_traits, checkIfExists:true) - .splitText(by: params.tiledb_batch_size, keepHeader: true, file: true) - .map { batch_file -> - def batch_index = (batch_file.name =~ /\.(\d+)\.csv$/)[0][1] - tuple(batch_index, batch_file) - }.set { tiledb_metadata_batches } - RECOMPUTE_META(tiledb_metadata_batches) - + if (params.locusbreaker){ + Channel.fromPath(params.table_lb, checkIfExists:true) + .splitText(by: params.tiledb_batch_size, keepHeader: true, file: true) + .map { batch_file -> + def batch_index = (batch_file.name =~ /\.(\d+)\.csv$/)[0][1] + tuple(batch_index, batch_file) + }.set { tiledb_metadata_batches } + + EXPORT_LOCUSBREAKER(tiledb_metadata_batches) + } + + if (params.export_traits){ + Channel.fromPath(params.list_traits, checkIfExists:true) + .splitText(by: params.tiledb_batch_size, keepHeader: true, file: true) + .map { batch_file -> + def batch_index = (batch_file.name =~ /\.(\d+)\.csv$/)[0][1] + tuple(batch_index, batch_file) + }.set { tiledb_metadata_batches } + + TRAITS(tiledb_metadata_batches) + } + + if (params.recompute_meta){ + Channel.fromPath(params.list_traits, checkIfExists:true) + .splitText(by: params.tiledb_batch_size, keepHeader: true, file: true) + .map { batch_file -> + def batch_index = (batch_file.name =~ /\.(\d+)\.csv$/)[0][1] + tuple(batch_index, batch_file) + }.set { tiledb_metadata_batches } + + RECOMPUTE_META(tiledb_metadata_batches) } } diff --git a/modules/create_tiledb/main.nf b/modules/create_tiledb/main.nf index f4953dd..a9814f3 100644 --- a/modules/create_tiledb/main.nf +++ b/modules/create_tiledb/main.nf @@ -7,6 +7,7 @@ process CREATE_TILEDB { input: path(mapping_file) val dummy + // Define output output: path "TileDB_${params.tiledb_name}", emit: tiledb_storage @@ -22,4 +23,10 @@ process CREATE_TILEDB { touch dummy_file """ -} \ No newline at end of file + + stub: + """ + mkdir -p TileDB_${params.tiledb_name} + touch dummy_file + """ +} diff --git a/modules/ingestion/main.nf b/modules/ingestion/main.nf index 7100ba9..274410f 100644 --- a/modules/ingestion/main.nf +++ b/modules/ingestion/main.nf @@ -1,25 +1,24 @@ #!/usr/bin/env nextflow process INGEST_DATA { - label "process_high" - //publishDir "${params.outdir}/TileDB/", mode: 'link' + label "process_high" + //publishDir "${params.outdir}/TileDB/", mode: 'link' + // Define input + input: + path(tiledb) + each path(list_files) + path(mapping_file) + path(dummy_file) -// Define input - input: - path(tiledb) - each path(list_files) - path(mapping_file) - path(dummy_file) - -// Define output - output: + // Define output + output: path("TileDB_${params.tiledb_name}_metadata_parts_${list_files.name}"), emit: metadata_parts path("ingestion_complete_${list_files.name}"), emit: ingestion_done path("${tiledb}"), emit: tiledb_updated -// Define the shell script to execute - script: + // Define the shell script to execute + script: def qc = params.qc ? "--qc" : "" def pvar_file = params.pvar_file ? "--pvar-file ${params.pvar_file}" : "" def permuted = params.permuted ? "--permuted" : "" @@ -31,6 +30,7 @@ process INGEST_DATA { --type-sumstat ${params.type_sumstat} \ --maf ${params.maf} \ --mac ${params.mac} ${qc} ${pvar_file} ${permuted} + # Rename the metadata parts directory to include the list_files name for uniqueness if [ -d "TileDB_${params.tiledb_name}_metadata_parts" ]; then mv "TileDB_${params.tiledb_name}_metadata_parts" "TileDB_${params.tiledb_name}_metadata_parts_${list_files.name}" @@ -38,10 +38,14 @@ process INGEST_DATA { # Create empty directory if none was created mkdir -p "TileDB_${params.tiledb_name}_metadata_parts_${list_files.name}" fi - # Create a dummy file to signal completion touch ingestion_complete_${list_files.name} - + """ + + stub: + """ + mkdir -p TileDB_${params.tiledb_name}_metadata_parts_${list_files.name} + touch ingestion_complete_${list_files.name} """ } diff --git a/modules/locusbreaker/main.nf b/modules/locusbreaker/main.nf index 537d1c7..c3d7026 100644 --- a/modules/locusbreaker/main.nf +++ b/modules/locusbreaker/main.nf @@ -1,21 +1,20 @@ #!/usr/bin/env nextflow process EXPORT_LOCUSBREAKER { - label "process_high" - publishDir "${params.outdir}/gwas_and_loci_tables", mode: params.publish_dir_mode + label "process_high" + publishDir "${params.outdir}/gwas_and_loci_tables", mode: params.publish_dir_mode + // Define input + input: + tuple val(batch_index), path(traits_list_table) -// Define input - input: - tuple val(batch_index), path(traits_list_table) + // Define output + output: + path("*_interval.csv"), emit: locus_breaker_tdb_intervals, optional: true + path("*_segment.csv"), emit: locus_breaker_tdb_segments, optional: true -// Define output - output: - path("*_interval.csv"), emit:locus_breaker_tdb_intervals, optional: true - path("*_segment.csv"), emit:locus_breaker_tdb_segments, optional: true - -// Define the shell script to execute - script: + // Define the shell script to execute + script: """ tdbsumstat export \ --table-lb ${traits_list_table} \ @@ -28,4 +27,10 @@ process EXPORT_LOCUSBREAKER { --locusbreaker \ --batch-name ${batch_index} """ + + stub: + """ + touch stub_${batch_index}_interval.csv + touch stub_${batch_index}_segment.csv + """ } diff --git a/modules/merge_metadata/main.nf b/modules/merge_metadata/main.nf index 8c813b8..8e5a216 100644 --- a/modules/merge_metadata/main.nf +++ b/modules/merge_metadata/main.nf @@ -1,56 +1,63 @@ +#!/usr/bin/env nextflow + process MERGE_METADATA { - label "process_high" - publishDir "${params.outdir}/TileDB/", mode: 'copy', pattern: "TileDB_${params.tiledb_name}" - publishDir "${params.outdir}/TileDB/", mode: 'copy', pattern: "TileDB_${params.tiledb_name}_metadata.csv" - - - input: - path(tiledb) - path(mapping_file) - path(metadata_parts) - path(ingestion_signals) - - output: - path("${tiledb}"), emit: tiledb_final - path("TileDB_${params.tiledb_name}_metadata.csv"), emit: metadata - path("tiledb_with_metadata"), emit: completion_signal - - script: - """ - # Create the main metadata_parts directory - mkdir -p TileDB_${params.tiledb_name}_metadata_parts - - # Copy all JSON files from all input directories - for parts_dir in ${metadata_parts}; do - if [ -d "\$parts_dir" ]; then - - # Extract the trailing number before .csv from the input folder - base=\$(basename "\$parts_dir") - base="\${base%.csv}" - suffix="\${base##*.}" - - for json in "\$parts_dir"/*.json; do - [ -e "\$json" ] || continue - - # Add that trailing number to .json file name - base=\$(basename "\$json") - name="\${base%.json}" - - cp -v "\$json" "TileDB_${params.tiledb_name}_metadata_parts/\${name}_\${suffix}.json" - done - fi - done - - echo "Total JSON files collected:" - ls TileDB_${params.tiledb_name}_metadata_parts/*.json 2>/dev/null | wc -l || echo "0" - - tdbsumstat ingest \ - --uri-path ${tiledb} \ - --mapping-file ${mapping_file} \ - --type-sumstat ${params.type_sumstat} \ - --only-meta - - # Signal that metadata merge is complete - touch tiledb_with_metadata - """ + label "process_high" + publishDir "${params.outdir}/TileDB/", mode: 'copy', pattern: "TileDB_${params.tiledb_name}" + publishDir "${params.outdir}/TileDB/", mode: 'copy', pattern: "TileDB_${params.tiledb_name}_metadata.csv" + + input: + path(tiledb) + path(mapping_file) + path(metadata_parts) + path(ingestion_signals) + + output: + path("${tiledb}"), emit: tiledb_final + path("TileDB_${params.tiledb_name}_metadata.csv"), emit: metadata + path("tiledb_with_metadata"), emit: completion_signal + + script: + """ + # Create the main metadata_parts directory + mkdir -p TileDB_${params.tiledb_name}_metadata_parts + + # Copy all JSON files from all input directories + for parts_dir in ${metadata_parts}; do + if [ -d "\$parts_dir" ]; then + + # Extract the trailing number before .csv from the input folder + base=\$(basename "\$parts_dir") + base="\${base%.csv}" + suffix="\${base##*.}" + + for json in "\$parts_dir"/*.json; do + [ -e "\$json" ] || continue + + # Add that trailing number to .json file name + base=\$(basename "\$json") + name="\${base%.json}" + + cp -v "\$json" "TileDB_${params.tiledb_name}_metadata_parts/\${name}_\${suffix}.json" + done + fi + done + + echo "Total JSON files collected:" + ls TileDB_${params.tiledb_name}_metadata_parts/*.json 2>/dev/null | wc -l || echo "0" + + tdbsumstat ingest \ + --uri-path ${tiledb} \ + --mapping-file ${mapping_file} \ + --type-sumstat ${params.type_sumstat} \ + --only-meta + + # Signal that metadata merge is complete + touch tiledb_with_metadata + """ + + stub: + """ + touch TileDB_${params.tiledb_name}_metadata.csv + touch tiledb_with_metadata + """ } diff --git a/modules/recompute_meta/main.nf b/modules/recompute_meta/main.nf index a600bde..b25bf76 100644 --- a/modules/recompute_meta/main.nf +++ b/modules/recompute_meta/main.nf @@ -1,26 +1,32 @@ -process RECOMPUTE_META{ +#!/usr/bin/env nextflow + +process RECOMPUTE_META { label 'process_high' publishDir "${params.outdir}/gwas_and_loci_tables/", mode: params.publish_dir_mode - - // Define input + // Define input input: - tuple val(batch_index), path(traits_list_table) - + tuple val(batch_index), path(traits_list_table) + // Define output output: - path("*.csv"), emit:ltbd_traits, optional: true - + path("*.csv"), emit: ltbd_traits, optional: true + // Define the shell script to execute script: - """ - tdbsumstat \ - export \ - --recompute-meta \ - --mac ${params.mac} \ - --trait-list ${traits_list_table} \ - --uri-path ${params.uri_path} \ - --batch-name ${batch_index} \ - --type-sumstat ${params.type_sumstat} - """ + """ + tdbsumstat \ + export \ + --recompute-meta \ + --mac ${params.mac} \ + --trait-list ${traits_list_table} \ + --uri-path ${params.uri_path} \ + --batch-name ${batch_index} \ + --type-sumstat ${params.type_sumstat} + """ + + stub: + """ + touch stub_recompute_${batch_index}.csv + """ } diff --git a/modules/regions/main.nf b/modules/regions/main.nf index 0012daa..873d11a 100644 --- a/modules/regions/main.nf +++ b/modules/regions/main.nf @@ -1,29 +1,35 @@ #!/usr/bin/env nextflow process EXPORT_REGIONS { - label "process_high" - //conda '/software/cardinal_analysis/ht/conda_envs/tdbsumstat' + label "process_high" + publishDir "${params.outdir}/results/regions_export/", mode: params.publish_dir_mode - publishDir "${params.outdir}/results/gwas_and_loci_tables/", mode: params.publish_dir_mode + // Define input + input: + tuple val(batch_index), path(regions_table) + // Define output + output: + path("*.csv"), emit: regions_output, optional: true -// Define input - input: - tuple val(batch_index), path(traits_list_table) + // Define the shell script to execute + script: + """ + tdbsumstat export \ + --table-regions ${regions_table} \ + --uri-path ${params.uri_path} \ + --type-sumstat ${params.type_sumstat} \ + --out ${params.out}_${batch_index} \ + --attr ${params.attrs} -// Define output - output: - path("*_interval.csv"), emit:locus_breaker_tdb_intervals, optional: true - tuple path("dummy_index"), path("*_segment.csv"), emit:locus_breaker_tdb_segments, optional: true + # Ensure output has .csv extension + for f in ${params.out}_${batch_index}*; do + [ -f "\$f" ] && [[ "\${f}" != *.csv ]] && mv "\$f" "\${f}.csv" + done + """ -// Define the shell script to execute - script: + stub: """ - tdbsumstat --workers ${params.workers} \ - export \ - --table_regions ${traits_list_table} \ - --uri-path ${params.uri_path} \ - --type-sumstat ${params.tiledb_lb_typesumstat} \ - --batch-name ${batch_index} + touch stub_regions_${batch_index}.csv """ } diff --git a/modules/snp/main.nf b/modules/snp/main.nf index 358d390..093eedc 100644 --- a/modules/snp/main.nf +++ b/modules/snp/main.nf @@ -1,3 +1,5 @@ +#!/usr/bin/env nextflow + process EXPORT_SNP { label "process_high" @@ -15,7 +17,7 @@ process EXPORT_SNP { // Get column names and create header def columnNames = rows[0].keySet().toList().sort() def header = columnNames.join(',') - + """ # Create header echo "${header}" > snp_batch_${chr}.csv @@ -23,7 +25,7 @@ process EXPORT_SNP { ${rows.collect { row -> def line = columnNames.collect { col -> row[col] ?: '' }.join(',') "echo '${line}' >> snp_batch_${chr}.csv" - }.join('\n ')} + }.join('\n ')} # Run the tdbsumstat command tdbsumstat export \ --snp snp_batch_${chr}.csv \ @@ -32,4 +34,9 @@ process EXPORT_SNP { --out ${params.out} \ --type-sumstat ${params.type_sumstat} """ + + stub: + """ + touch ${params.out}_chr${chr}_stub.csv + """ } diff --git a/modules/traits/main.nf b/modules/traits/main.nf index 69b2311..aff5f22 100644 --- a/modules/traits/main.nf +++ b/modules/traits/main.nf @@ -1,24 +1,30 @@ -process TRAITS{ +#!/usr/bin/env nextflow + +process TRAITS { label 'process_high' publishDir "${params.outdir}/gwas_and_loci_tables/", mode: params.publish_dir_mode - - // Define input + // Define input input: - tuple val(batch_index), path(traits_list_table) - + tuple val(batch_index), path(traits_list_table) + // Define output output: - path("*_${batch_index}.csv"), emit:ltbd_traits, optional: true - + path("*_${batch_index}.csv"), emit: ltbd_traits, optional: true + // Define the shell script to execute script: - """ - tdbsumstat \ - export \ - --trait-list ${traits_list_table} \ - --uri-path ${params.uri_path} \ - --batch-name ${batch_index} \ - --type-sumstat ${params.type_sumstat} - """ + """ + tdbsumstat \ + export \ + --trait-list ${traits_list_table} \ + --uri-path ${params.uri_path} \ + --batch-name ${batch_index} \ + --type-sumstat ${params.type_sumstat} + """ + + stub: + """ + touch stub_traits_${batch_index}.csv + """ } diff --git a/scripts/create_metadata.py b/scripts/create_metadata.py new file mode 100755 index 0000000..8c93977 --- /dev/null +++ b/scripts/create_metadata.py @@ -0,0 +1,69 @@ +import json +from collections import defaultdict +input_path = "/lustre/scratch124/humgen/projects_v2/cardinal_analysis/analysis/core_dataset/freeze3/tiledbs/Tensor/TileDB_f3_UKB_cis_t2_metadata.json" +output_path = input_path.replace(".json", "_fixed.json") + +objs = [] +with open(input_path) as f: + text = f.read() + +decoder = json.JSONDecoder() +idx = 0 +while idx < len(text): + obj, idx = decoder.raw_decode(text, idx) + objs.append(obj) + +with open(output_path, "w") as f: + json.dump(objs, f, indent=2) + +print(f"✅ Salvaged {len(objs)} metadata records into {output_path}") + + +fixed_path = "/lustre/scratch124/humgen/projects_v2/cardinal_analysis/analysis/core_dataset/freeze3/tiledbs/Tensor/TileDB_f3_UKB_cis_t2_metadata_fixed.json" +output_path = fixed_path.replace("_fixed.json", "_merged.json") + +with open(fixed_path) as f: + metadata_records = json.load(f) + +# Create a merged dictionary +merged_metadata = { + "file_path": [], + "trait": [], + "celltype": [] +} + +# For storing per-cell/chromosome info if present +cell_chrom_data = defaultdict(lambda: defaultdict(list)) + +for record in metadata_records: + # Merge file paths + if "file_path" in record and record["file_path"] not in merged_metadata["file_path"]: + merged_metadata["file_path"].append(record["file_path"]) + # Merge traits + if len(record["trait"]) > 0: + for t in record["trait"]: + if t not in merged_metadata["trait"]: + merged_metadata["trait"].append(t) + # Merge celltypes and their per-chromosome data + if len(record["celltype"]) > 0: + for cell in record["celltype"]: + if cell not in merged_metadata["celltype"]: + merged_metadata["celltype"].append(cell) + # Merge chromosome-level info if exists + if cell in record: + for chrom, genes in record[cell].items(): + cell_chrom_data[cell][chrom] = {} + #existing_genes = {g for g in cell_chrom_data[cell][chrom]} + for g in genes: + #if g not in existing_genes: + cell_chrom_data[cell][chrom][g] = genes[g] + +# Add per-cell/chromosome info +for cell, chrom_dict in cell_chrom_data.items(): + merged_metadata[cell] = chrom_dict + +# Save as a single JSON object +with open(output_path, "w") as f: + json.dump(merged_metadata, f, indent=2) + +print(f"✅ Merged metadata saved to {output_path}") diff --git a/scripts/fix_json.py b/scripts/fix_json.py new file mode 100644 index 0000000..ef83c6c --- /dev/null +++ b/scripts/fix_json.py @@ -0,0 +1,55 @@ +import json +import re +from collections import defaultdict + +# === STEP 1: Read the entire string from file === +with open("/project/cardinal/QTLs/freeze3/TileDBs/TileDB_metanalyses_gh_celltype2_freeze3_metadata.json", "r", encoding="utf-8") as f: + data_str = f.read() + +# === STEP 2: Split based on the start of each JSON fragment === +# We capture the first '{' before each file_path +fragments = re.findall(r'(\{[^{]*"file_path":.*?)(?=\{[^{]*"file_path":|\Z)', data_str, flags=re.S) + +print(f"🧩 Found {len(fragments)} fragments") + +# === STEP 3: Parse each fragment === +parsed_fragments = [] +for i, frag in enumerate(fragments): + try: + parsed_fragments.append(json.loads(frag)) + except json.JSONDecodeError as e: + print(f"⚠️ Fragment {i} failed to parse at char {e.pos}: {e}") + print(frag[:300] + "...") + # optional: skip or raise + continue + +# === STEP 4: Merge fragments as before === +merged = { + "trait": [], + "celltype": [], +} +celltype_data = defaultdict(lambda: defaultdict(dict)) + +for frag in parsed_fragments: + if "trait" in frag and isinstance(frag["trait"], list): + merged["trait"].extend(frag["trait"]) + if "celltype" in frag and isinstance(frag["celltype"], list): + merged["celltype"].extend(frag["celltype"]) + for key, val in frag.items(): + if key in ("trait", "celltype", "CELL", "file_path"): + continue + for num, genes in val.items(): + for gene_id, gene_data in genes.items(): + celltype_data[key][num][gene_id] = gene_data + +for celltype, numbers in celltype_data.items(): + merged[celltype] = numbers + +merged["trait"] = list(dict.fromkeys(merged["trait"])) +merged["celltype"] = list(dict.fromkeys(merged["celltype"])) + +# === STEP 5: Save merged JSON === +with open("metadata_merged.json", "w", encoding="utf-8") as out_f: + json.dump(merged, out_f, indent=2) + +print("✅ Merged JSON written to metadata_merged.json") diff --git a/scripts/generate_table_cell_sumstat.py b/scripts/generate_table_cell_sumstat.py new file mode 100755 index 0000000..43a4409 --- /dev/null +++ b/scripts/generate_table_cell_sumstat.py @@ -0,0 +1,22 @@ +import pandas as pd +import tiledb +rows = [] +tdb = tiledb.open('/lustre/scratch124/humgen/projects_v2/cardinal_analysis/analysis/core_dataset/freeze3/tiledbs/Tensor/TileDB_f3_UKB_cis_t2', 'w') +# Loop over all celltypes in metadata +for celltype in merged_metadata["celltype"]: + if celltype in merged_metadata: # make sure the key exists in dict + groups = merged_metadata[celltype] + for group, values in groups.items(): # e.g. group "11" + for gene_id in values: + rows.append({ + "CHR": group, + "CELL": celltype, + "GENE": gene_id, + "N": values[gene_id]["N"], + "ACAT": values[gene_id]["ACAT"], + "PHENOVAR": values[gene_id]["PHENO_VAR"], + }) +df = pd.DataFrame(rows) + +tdb.meta["metadata"] = json.dumps(merged_metadata) +df.to_csv("/lustre/scratch124/humgen/projects_v2/cardinal_analysis/analysis/core_dataset/freeze3/tiledbs/Tensor/Bangladeshi/metadata_gh_bangladeshi_f3_celltype1_acat.csv",index = False) \ No newline at end of file diff --git a/tdbsumstat/cli/export.py b/tdbsumstat/cli/export.py index b6ea133..dad210b 100755 --- a/tdbsumstat/cli/export.py +++ b/tdbsumstat/cli/export.py @@ -1,3 +1,21 @@ +# This file is superseded by the tdbsumstat/cli/export/ package. +# Python loads the package (directory with __init__.py) in preference to this file. +# It is kept for reference only; all logic now lives in the export/ sub-modules: +# export/helpers.py – common TileDB helpers +# export/snp.py – SNP-based export +# export/regions.py – region-based export +# export/locusbreaker.py – locusbreaker export +# export/metadata.py – metadata export / recompute +# export/traits.py – trait-based export +# export/command.py – CLI command definition and routing +# export/__init__.py – re-exports the `export` command + +from tdbsumstat.cli.export.command import export # noqa: F401 + +# --------------------------------------------------------------------------- +# Legacy code kept below for historical reference only +# --------------------------------------------------------------------------- + import tiledb import click import cloup @@ -14,7 +32,7 @@ Query TileDB database and export data. """ -@cloup.command("export", no_args_is_help=True, help=help_doc) +@cloup.command("export_legacy", no_args_is_help=True, help=help_doc) @cloup.option_group( "Options for querying specific chromosomes, cells, genes or positions in the TileDB", cloup.option("--uri-path", default = None, type=str, help = "path of TileDB"), diff --git a/tdbsumstat/cli/export/__init__.py b/tdbsumstat/cli/export/__init__.py new file mode 100644 index 0000000..e229e84 --- /dev/null +++ b/tdbsumstat/cli/export/__init__.py @@ -0,0 +1,4 @@ +"""Export package – re-exports the ``export`` CLI command.""" +from tdbsumstat.cli.export.command import export + +__all__ = ["export"] diff --git a/tdbsumstat/cli/export/command.py b/tdbsumstat/cli/export/command.py new file mode 100644 index 0000000..12c2386 --- /dev/null +++ b/tdbsumstat/cli/export/command.py @@ -0,0 +1,141 @@ +"""CLI command definition for the ``export`` subcommand. + +This module wires CLI options to the individual export handler functions +defined in the sibling modules (snp, regions, locusbreaker, metadata, traits). +""" +import click +import cloup + +from tdbsumstat.cli.export.helpers import open_tiledb_and_load_metadata +from tdbsumstat.cli.export.locusbreaker import export_with_locusbreaker +from tdbsumstat.cli.export.metadata import export_metadata, recompute_metadata +from tdbsumstat.cli.export.regions import export_by_regions +from tdbsumstat.cli.export.snp import export_by_snp +from tdbsumstat.cli.export.traits import export_by_traits + +help_doc = """ +Query TileDB database and export data. +""" + + +@cloup.command("export", no_args_is_help=True, help=help_doc) +@cloup.option_group( + "Options for querying specific chromosomes, cells, genes or positions in the TileDB", + cloup.option("--uri-path", default=None, type=str, help="path of TileDB"), + cloup.option("--table-regions", default=None, type=str, help="Regions to interrogate from a table"), + cloup.option("--trait-list", default=None, type=str, help="List of entire traits to filter"), + cloup.option("--attr", default="P,SNPID,EAF,BETA,SE", type=str, help="Attributes to output"), + cloup.option("--export-meta", is_flag=True, default=False, type=str, help="Get metadata from TileDB"), + cloup.option("--mac", default=0, type=int, help="Filter for MAC when recomputing metadata"), + cloup.option( + "--recompute-meta", + is_flag=True, + default=False, + type=str, + help="Recompute metadata after applying filters (Does not modify data within the TileDB)", + ), + cloup.option( + "--snp", + default=None, + type=str, + help="List of SNPs to interrogate taken from a txt file. Please check README for details on the format of this file", + ), + cloup.option("--batch-name", default=None, type=str, help="Name of the batch"), +) +@cloup.option_group( + "Options for Locusbreaker", + cloup.option("--locusbreaker", is_flag=True, type=bool, default=False, help="Option to run locusbreaker"), + cloup.option( + "--hole-lb", + default=250000, + type=int, + help="Minimum base-pair distance between SNPs in different loci (default: 250000)", + ), + cloup.option( + "--maf-lb", + default=0.001, + type=float, + help="The MAF to filter the TILEDB before locusbreaker is run", + ), + cloup.option( + "--locus-max-size-lb", + default=3000000, + type=float, + help="The maximum size allowed for the locus. Default: 1Mb", + ), + cloup.option( + "--cis-trans-lb", + default="cis", + type=str, + help="If locusbreaker run on cis or trans QLTs", + ), + cloup.option("--table-lb", default=None, type=str, help="Path of the table to provide"), + cloup.option("--type-sumstat", default=None, type=str, help="Type of summary data"), +) +@cloup.option_group( + "Options for output", + cloup.option( + "--out", + default="out", + type=str, + help="Output path with file name where results will be stored", + ), +) +@click.pass_context +def export( + ctx, + uri_path: str, + type_sumstat: str, + table_regions: str, + trait_list: str, + mac: int, + attr: str, + snp: str, + export_meta: bool, + recompute_meta: bool, + locusbreaker: bool, + maf_lb: float, + cis_trans_lb: str, + table_lb: str, + hole_lb: int, + out: str, + locus_max_size_lb: int, + batch_name: str, +): + """Route the export command to the appropriate handler based on CLI flags.""" + if snp: + tiledb_export, _df_meta = open_tiledb_and_load_metadata(uri_path, type_sumstat) + export_by_snp(tiledb_export, snp, attr, type_sumstat, out) + tiledb_export.close() + + elif table_regions: + tiledb_export, _df_meta = open_tiledb_and_load_metadata(uri_path, type_sumstat) + export_by_regions(tiledb_export, table_regions, attr, type_sumstat, out) + tiledb_export.close() + + elif locusbreaker: + _tiledb_export, df_meta = open_tiledb_and_load_metadata(uri_path, type_sumstat) + _tiledb_export.close() + export_with_locusbreaker( + uri_path=uri_path, + df_meta=df_meta, + table_lb=table_lb, + maf_lb=maf_lb, + hole_lb=hole_lb, + locus_max_size_lb=locus_max_size_lb, + cis_trans_lb=cis_trans_lb, + type_sumstat=type_sumstat, + out=out, + batch_name=batch_name, + ) + + elif export_meta: + export_metadata(uri_path, type_sumstat, out) + + elif recompute_meta: + tiledb_export, df_meta = open_tiledb_and_load_metadata(uri_path, type_sumstat) + recompute_metadata(tiledb_export, df_meta, trait_list, type_sumstat, mac, out, batch_name) + tiledb_export.close() + + else: + export_by_traits(uri_path, trait_list, attr, type_sumstat, out, batch_name) diff --git a/tdbsumstat/cli/export/helpers.py b/tdbsumstat/cli/export/helpers.py new file mode 100644 index 0000000..4ca5ddc --- /dev/null +++ b/tdbsumstat/cli/export/helpers.py @@ -0,0 +1,45 @@ +"""Common TileDB helper functions for export operations.""" +import json + +import polars as pl +import tiledb + + +def open_tiledb_and_load_metadata(uri_path: str, type_sumstat: str): + """Open TileDB array and load metadata as a Polars DataFrame. + + Parameters + ---------- + uri_path : str + Path to the TileDB array. + type_sumstat : str + Type of summary statistics: "gwas" or "qtl". + + Returns + ------- + tuple[tiledb.Array, pl.DataFrame] + Open TileDB array (read mode) and a Polars DataFrame with metadata. + """ + tiledb_export = tiledb.open(uri_path, mode="r") + metadata = json.loads(tiledb_export.meta["merged_metadata"]) + rows = [] + if type_sumstat == "qtl": + for cell in metadata["CELL"]: + for chrom, genes in metadata[cell].items(): + for gene, stats in genes.items(): + rows.append({ + "CELL": cell, + "CHR": chrom, + "GENE": gene, + **stats + }) + df_meta = pl.DataFrame(rows) + df_meta = df_meta.with_columns(pl.col("CHR").cast(pl.UInt16)) + else: + for trait in metadata["trait"]: + rows.append({ + "TRAIT": trait, + **metadata[trait] + }) + df_meta = pl.DataFrame(rows) + return tiledb_export, df_meta diff --git a/tdbsumstat/cli/export/locusbreaker.py b/tdbsumstat/cli/export/locusbreaker.py new file mode 100644 index 0000000..6210d7e --- /dev/null +++ b/tdbsumstat/cli/export/locusbreaker.py @@ -0,0 +1,124 @@ +"""Locusbreaker-based export from TileDB.""" +import os +import random + +import pandas as pd +import polars as pl +import tiledb + +from tdbsumstat.utils.locusbreaker_plpl import locusbreaker_plpl + + +def _query_tiledb_for_locusbreaker( + uri_path: str, + chrom: int, + type_sumstat: str, + trait: str = None, + cell: str = None, + gene: str = None, +) -> "pa.Table": + """Query TileDB for a specific chromosome/trait combination. + + Returns a PyArrow table for use with locusbreaker_plpl. + """ + with tiledb.open(uri_path, mode="r") as tiledb_data: + if type_sumstat == "gwas": + return tiledb_data.query(dims=["CHR", "TRAIT", "POS"]).df[chrom, trait, :] + else: + return tiledb_data.query(dims=["CHR", "CELL", "GENE", "POS"], return_arrow=True).df[ + chrom, cell, gene, : + ] + + +def export_with_locusbreaker( + uri_path: str, + df_meta: pl.DataFrame, + table_lb: str, + maf_lb: float, + hole_lb: int, + locus_max_size_lb: int, + cis_trans_lb: str, + type_sumstat: str, + out: str, + batch_name: str, + pvalue_sig: float = 5e-8, + pvalue_limit: float = 5e-6, +) -> None: + """Run locusbreaker on TileDB data and export loci intervals and segments. + + Parameters + ---------- + uri_path : str + Path to the TileDB array. + df_meta : pl.DataFrame + Polars DataFrame with merged metadata (used by locusbreaker_plpl). + table_lb : str + Path to a CSV table with CHR, TRAIT (and optionally SIG, LIM columns). + maf_lb : float + MAF filter applied before locusbreaker. + hole_lb : int + Minimum base-pair distance to separate loci. + locus_max_size_lb : int + Maximum allowed locus size in base pairs. + cis_trans_lb : str + Filter type: "cis" or "trans" (for QTL data). + type_sumstat : str + Type of summary statistics: "gwas" or "qtl". + out : str + Output file prefix. + batch_name : str + Batch identifier appended to output file names. + pvalue_sig : float + P-value threshold for significant SNPs (default: 5e-8). + pvalue_limit : float + P-value threshold for locus boundary definition (default: 5e-6). + """ + print("Starting LocusBreaker") + traits = pd.read_csv(table_lb) + traits = traits.astype({"CHR": "int16"}) + + if not batch_name: + batch_name = random.randint(1, 10000000) + + for _index, trait in traits.iterrows(): + if "SIG" in traits.columns: + pvalue_sig = trait["SIG"] + pvalue_limit = trait["LIM"] + + if type_sumstat == "gwas": + query = _query_tiledb_for_locusbreaker(uri_path, trait["CHR"], type_sumstat, trait=trait["TRAIT"]) + else: + cell, genes = trait["TRAIT"].split(";") + query = _query_tiledb_for_locusbreaker(uri_path, trait["CHR"], type_sumstat, cell=cell, gene=genes) + + result = locusbreaker_plpl( + query, + maf=maf_lb, + pvalue_sig=pvalue_sig, + pvalue_limit=pvalue_limit, + locus_max_size=locus_max_size_lb, + hole_size=hole_lb, + cis_trans_lb=cis_trans_lb, + type_sumstat=type_sumstat, + metadata=df_meta, + ) + + if not len(result) == 0 and not result[0].empty: + if result and isinstance(result[0], pd.DataFrame) and not result[0].shape[0] == 0: + interval = result[0] + segments = result[1] + + write_header_interval = not os.path.exists(f"{out}_batch_{batch_name}_interval.csv") + write_header_segment = not os.path.exists(f"{out}_batch_{batch_name}_segment.csv") + interval.to_csv( + f"{out}_batch_{batch_name}_interval.csv", + mode="a", + index=False, + header=write_header_interval, + ) + segments.to_csv( + f"{out}_batch_{batch_name}_segment.csv", + mode="a", + index=False, + header=write_header_segment, + ) diff --git a/tdbsumstat/cli/export/metadata.py b/tdbsumstat/cli/export/metadata.py new file mode 100644 index 0000000..817ccb7 --- /dev/null +++ b/tdbsumstat/cli/export/metadata.py @@ -0,0 +1,135 @@ +"""Metadata export and recomputation from TileDB.""" +import json + +import pandas as pd +import polars as pl +import tiledb + +from tdbsumstat.utils import acat_optimized + + +def export_metadata(uri_path: str, type_sumstat: str, out: str) -> None: + """Export merged metadata from TileDB to a CSV file. + + Parameters + ---------- + uri_path : str + Path to the TileDB array. + type_sumstat : str + Type of summary statistics: "gwas" or "qtl". + out : str + Output file prefix (``{out}_meta.csv`` will be created). + """ + tiledb_db = tiledb.open(uri_path, mode="r") + tiledb_meta = json.loads(tiledb_db.meta["merged_metadata"]) + rows = [] + + if type_sumstat == "qtl": + for cell_type in tiledb_meta["CELL"]: + samples = tiledb_meta.get(cell_type, {}) + for sample_id, genes in samples.items(): + for gene_id, metrics in genes.items(): + rows.append({ + "CELL": cell_type, + "CHR": sample_id, + "GENE": gene_id, + **metrics, + }) + else: + for trait in tiledb_meta["traits"]: + samples = tiledb_meta.get(trait, {}) + for chrom, genes in samples.items(): + for gene_id, metrics in genes.items(): + rows.append({ + "TRAIT": trait, + "CHR": chrom, + **metrics, + }) + + df = pd.DataFrame(rows) + df.to_csv(f"{out}_meta.csv", index=False) + tiledb_db.close() + + +def recompute_metadata( + tiledb_export: tiledb.Array, + df_meta: pl.DataFrame, + trait_list: str, + type_sumstat: str, + mac: int, + out: str, + batch_name: str, +) -> None: + """Recompute metadata statistics after applying MAC filter and save to CSV. + + This does **not** modify data stored inside the TileDB array. + + Parameters + ---------- + tiledb_export : tiledb.Array + Open TileDB array in read mode. + df_meta : pl.DataFrame + Polars DataFrame with merged metadata. + trait_list : str + Path to a CSV file with traits/cells to recompute. + type_sumstat : str + Type of summary statistics: "gwas" or "qtl". + mac : int + Minimum minor allele count filter. + out : str + Output file prefix. + batch_name : str + Batch identifier appended to output file names. + """ + trait_list_pd = pd.read_csv(trait_list) + + for _record, trait in trait_list_pd.iterrows(): + if type_sumstat == "gwas": + tiledb_query = tiledb_export.query().df[int(trait["CHR"]), trait["TRAIT"].to_string(), :] + n = df_meta.filter(pl.col("TRAIT") == trait["TRAIT"]).select("N")["N"][0] + else: + print(trait["CELL"]) + tiledb_query = tiledb_export.query().df[int(trait["CHR"]), trait["CELL"], :, :] + n = df_meta.filter(pl.col("CELL") == trait["CELL"]).select("N")["N"][0] + print(n) + + if "N" not in tiledb_query.columns: + tiledb_query["N"] = n + print(tiledb_query) + + tiledb_query_pl = pl.from_pandas(tiledb_query) + tiledb_query_pl = tiledb_query_pl.with_columns( + (2 * pl.col("N") * pl.min_horizontal("EAF", (1 - pl.col("EAF")))).alias("MAC") + ).filter(pl.col("MAC") > mac) + + if type_sumstat == "gwas": + chr_gene_agg = tiledb_query_pl.group_by(["CHR", "TRAIT"]).agg([ + pl.col("P") + .map_batches( + lambda s: pl.Series([acat_optimized(s)]), + return_dtype=pl.Float64, + ) + .alias("ACAT_LIST"), + pl.col("N").first().alias("N"), + pl.min("P").alias("MIN_P"), + ]) + chr_gene_agg = chr_gene_agg.with_columns( + pl.col("ACAT_LIST").list.first().alias("ACAT") + ) + else: + chr_gene_agg = tiledb_query_pl.group_by(["CHR", "CELL", "GENE"]).agg([ + pl.col("P") + .map_batches( + lambda s: pl.Series([acat_optimized(s)]), + return_dtype=pl.Float64, + ) + .alias("ACAT_LIST"), + pl.col("N").first().alias("N"), + pl.min("P").alias("MIN_P"), + ]) + chr_gene_agg = chr_gene_agg.with_columns( + pl.col("ACAT_LIST").list.first().alias("ACAT"), + ).drop("ACAT_LIST") + + chr_gene_agg_pd = chr_gene_agg.to_pandas() + chr_gene_agg_pd.to_csv(f"{out}_batch_{batch_name}_metadata.csv", mode="a", index=False) diff --git a/tdbsumstat/cli/export/regions.py b/tdbsumstat/cli/export/regions.py new file mode 100644 index 0000000..3fdc047 --- /dev/null +++ b/tdbsumstat/cli/export/regions.py @@ -0,0 +1,50 @@ +"""Region-based export from TileDB.""" +import pandas as pd +import tiledb + + +def export_by_regions( + tiledb_export: tiledb.Array, + table_regions: str, + attr: str, + type_sumstat: str, + out: str, +) -> None: + """Query TileDB by genomic regions table and export results to CSV. + + Parameters + ---------- + tiledb_export : tiledb.Array + Open TileDB array in read mode. + table_regions : str + Path to a CSV file with columns CHR, START, END, TRAIT. + attr : str + Comma-separated list of attributes to export. + type_sumstat : str + Type of summary statistics: "gwas" or "qtl". + out : str + Output file path. + """ + pd_region = pd.read_csv(table_regions) + counter_nonempty_region = 0 + + for _ind, row in pd_region.iterrows(): + if type_sumstat == "gwas": + trait = row["TRAIT"] + region = tiledb_export.query( + dims=["CHR", "POS", "TRAIT"], + attrs=attr.split(","), + ).df[int(row["CHR"]), trait, int(row["START"]):int(row["END"])] + else: + cell, gene = row["TRAIT"].split(":") + region = tiledb_export.query( + dims=["CHR", "POS", "CELL", "GENE"], + attrs=attr.split(","), + ).df[int(row["CHR"]), cell, gene, int(row["START"]):int(row["END"])] + + if len(region) > 0: + if counter_nonempty_region == 0: + region.to_csv(out, mode="a", index=False, header=True) + counter_nonempty_region += 1 + else: + region.to_csv(out, mode="a", index=False, header=False) diff --git a/tdbsumstat/cli/export/snp.py b/tdbsumstat/cli/export/snp.py new file mode 100644 index 0000000..78a2a68 --- /dev/null +++ b/tdbsumstat/cli/export/snp.py @@ -0,0 +1,72 @@ +"""SNP-based export from TileDB.""" +import numpy as np +import pandas as pd +import polars as pl +import tiledb + + +def export_by_snp( + tiledb_export: tiledb.Array, + snp: str, + attr: str, + type_sumstat: str, + out: str, +) -> None: + """Query TileDB by a list of SNPs and export results to CSV. + + Parameters + ---------- + tiledb_export : tiledb.Array + Open TileDB array in read mode. + snp : str + Path to a CSV file with columns CHR, POS, TRAIT (and optionally GENE for QTL). + attr : str + Comma-separated list of attributes to export. + type_sumstat : str + Type of summary statistics: "gwas" or "qtl". + out : str + Output file prefix. + """ + snp_list = pd.read_csv(snp, dtype={"CHR": int, "POS": np.uint32, "TRAIT": str}) + + if type_sumstat == "gwas": + trait_list = snp_list["TRAIT"].unique().tolist() + else: + snp_list[["CELL", "GENE"]] = snp_list["TRAIT"].str.split(":", n=2, expand=True) + trait_list = snp_list["CELL"].unique().tolist() + + for trait in trait_list: + if type_sumstat == "gwas": + chrom_list = snp_list[snp_list["TRAIT"] == trait]["CHR"].unique().tolist() + else: + chrom_list = snp_list[snp_list["CELL"] == trait]["CHR"].unique().tolist() + + for chrom in chrom_list: + if type_sumstat == "gwas": + snp_list_refined = ( + snp_list[(snp_list["CHR"] == chrom) & (snp_list["TRAIT"] == trait)]["POS"] + .unique() + .tolist() + ) + tiledb_query = tiledb_export.query( + attrs=attr.split(","), + return_arrow=True, + ).df[chrom, trait, :] + tiledb_query_pl = pl.from_arrow(tiledb_query) + tiledb_query_pd = tiledb_query_pl.filter(pl.col("POS").is_in(snp_list_refined)).to_pandas() + else: + snp_list_refined = ( + snp_list[(snp_list["CHR"] == chrom) & (snp_list["CELL"] == trait)]["POS"] + .unique() + .tolist() + ) + gene_list = ( + snp_list[(snp_list["CHR"] == chrom) & (snp_list["CELL"] == trait)]["GENE"] + .unique() + .tolist() + ) + tiledb_query = tiledb_export.query(attrs=attr.split(",")).df[chrom, trait, gene_list, :] + tiledb_query_pl = pl.from_arrow(tiledb_query) + tiledb_query_pd = tiledb_query_pl.filter(pl.col("POS").is_in(snp_list_refined)).to_pandas() + + tiledb_query_pd.to_csv(f"{out}_{trait}_{chrom}.csv", mode="a", index=False) diff --git a/tdbsumstat/cli/export/traits.py b/tdbsumstat/cli/export/traits.py new file mode 100644 index 0000000..cefbb7a --- /dev/null +++ b/tdbsumstat/cli/export/traits.py @@ -0,0 +1,54 @@ +"""Trait-based bulk export from TileDB.""" +import pandas as pd +import tiledb + + +def export_by_traits( + uri_path: str, + trait_list: str, + attr: str, + type_sumstat: str, + out: str, + batch_name: str, +) -> None: + """Export all summary statistics for a list of traits/cells-genes to CSV. + + The function streams data in chunks to handle large datasets efficiently. + + Parameters + ---------- + uri_path : str + Path to the TileDB array. + trait_list : str + Path to a CSV file with a TRAIT column (and optionally CELL/GENE columns for QTL). + attr : str + Comma-separated list of attributes to export. + type_sumstat : str + Type of summary statistics: "gwas" or "qtl". + out : str + Output file prefix. + batch_name : str + Batch identifier appended to the output file name. + """ + trait_list_pd = pd.read_csv(trait_list) + + with tiledb.open(uri_path, mode="r") as array: + if type_sumstat == "gwas": + trait_list_np = trait_list_pd["TRAIT"].to_list() + tiledb_iterator = array.query( + return_incomplete=True, + attrs=attr.split(","), + ).df[:, trait_list_np, :] + else: + trait_list_pd[["cell", "gene"]] = trait_list_pd["TRAIT"].str.split(":", expand=True) + cells = trait_list_pd["cell"].to_list() + gene = trait_list_pd["gene"].to_list() + tiledb_iterator = array.query( + return_incomplete=True, + attrs=attr.split(","), + ).df[:, cells, gene, :] + + for chunk in tiledb_iterator: + chunk.to_csv(f"{out}_{batch_name}.csv", mode="a", index=False, header=False) + + print(f"Saved filtered summary statistics in {out}") diff --git a/tdbsumstat/cli/ingestion.py b/tdbsumstat/cli/ingestion.py index 0c45a6b..17cfd30 100755 --- a/tdbsumstat/cli/ingestion.py +++ b/tdbsumstat/cli/ingestion.py @@ -3,7 +3,7 @@ import os import click import cloup -from tdbsumstat.utils.harmonize_ingest import Harmonize +from tdbsumstat.utils.ingest import Harmonize import pandas as pd import polars as pl diff --git a/tdbsumstat/utils/create_dummy_data_sc.py b/tdbsumstat/utils/create_dummy_data_sc.py index c137b34..f2f2032 100755 --- a/tdbsumstat/utils/create_dummy_data_sc.py +++ b/tdbsumstat/utils/create_dummy_data_sc.py @@ -1,100 +1,169 @@ -import pandas as pd -import numpy as np -import click - -@click.command() -@click.option("--num_snps", default=10000, help="Total number of SNPs to create") -@click.option("--num_snps_gene", default=2000, help="How many SNPs each gene should have") -@click.option("--out_csv", default="dummy_out", help="Where to send the output") - -def create_dummy_data(num_snps, num_snps_gene, out_csv): - # Initialize lists for each column - - gene_ids = [] - variant_ids = [] - start_distances = [] - afs = [] - ma_samples = [] - ma_counts = [] - pval_nominals = [] - slopes = [] - slope_ses = [] - positions = [] - a1s = [] - a2s = [] - - # Keep track of generated variant IDs to avoid duplicates - generated_variant_ids = set() +"""Generate synthetic per-gene QTL tables for local tests (alleles and SNP column aligned).""" +from __future__ import annotations + +import argparse +import csv +import gzip +import random +from typing import Optional + +# Base genomic position offset per gene so (CHR, CELL, GENE, POS) never collides across genes +# when ingested into the same TileDB array. +_POS_OFFSET_PER_GENE = 100_000 + +_ALLELES = ("A", "T", "C", "G") + +_HEADER = [ + "Chr", + "Gene", + "cell.type", + "pos", + "a0", + "a1", + "SNP", + "START", + "EAF", + "p", + "beta", + "se", +] + + +def _build_variant_key(chrom: int, pos: int, al1: str, al2: str) -> tuple[str, str]: + """Return ordered pair of variant id strings for a locus (forward and reverse). + + Used to deduplicate the same physical SNP when alleles are swapped. + + Example: + >>> _build_variant_key(20, 100, "A", "G") + ('chr20:100:A:G', 'chr20:100:G:A') + """ + fwd = f"chr{chrom}:{pos}:{al1}:{al2}" + rev = f"chr{chrom}:{pos}:{al2}:{al1}" + return fwd, rev + + +def _random_allele_pair(rng: random.Random) -> tuple[str, str]: + """Draw two distinct nucleotides uniformly from A/T/C/G. + + Example: + >>> _random_allele_pair(random.Random(0)) + ('T', 'C') + """ + while True: + a1 = rng.choice(_ALLELES) + a2 = rng.choice(_ALLELES) + if a1 != a2: + return a1, a2 + + +def _generate_one_gene_rows( + rng: random.Random, + num_snps: int, + num_snps_gene: int, + gene_idx: int, + generated_variant_ids: set[str], +) -> tuple[str, list[dict]]: + """Build table rows for a single gene; returns (phenotype_id, rows). + + Example: + >>> r = random.Random(0) + >>> g, rows = _generate_one_gene_rows(r, 100, 3, 0, set()) + >>> len(rows) + 3 + """ + phenotype_id = f"ENSG00000{num_snps + gene_idx}" + pos_offset = gene_idx * _POS_OFFSET_PER_GENE + rows: list[dict] = [] + + for _ in range(num_snps_gene): + while True: + pos_local = rng.randrange(1, num_snps) + pos = pos_local + pos_offset + a1, a2 = _random_allele_pair(rng) + + variant_id, variant_reverse_id = _build_variant_key(20, pos, a1, a2) + + if variant_id not in generated_variant_ids and variant_reverse_id not in generated_variant_ids: + generated_variant_ids.add(variant_id) + generated_variant_ids.add(variant_reverse_id) + break + + rows.append( + { + "Chr": 20, + "Gene": phenotype_id, + "cell.type": "Tgd", + "pos": pos, + "a0": a1, + "a1": a2, + "SNP": variant_id, + "START": rng.randrange(-500_000, 500_000), + "EAF": rng.random(), + "p": rng.random(), + "beta": rng.uniform(-1, 1), + "se": rng.uniform(0.001, 1), + } + ) + + return phenotype_id, rows + + +def create_dummy_data( + num_snps: int, + num_snps_gene: int, + out_csv: str, + seed: Optional[int], + also_tsv: bool, +) -> None: + """Write two gzipped TSVs with disjoint positions per gene, random A/T/C/G alleles, SNP = chr:pos:a0:a1. + + Example: + ``create_dummy_data(10000, 2000, "dummy_out", seed=42, also_tsv=True)`` + writes ``dummy_out_ENSG0000010000.tsv.gz`` (and optionally ``.tsv``) with varied alleles per row. + """ + rng = random.Random(seed) num_genes = 2 + generated_variant_ids: set[str] = set() - #num_genes = round(num_snps / num_snps_gene) for gene_idx in range(num_genes): - # Generate unique phenotype_id for this gene - phenotype_id = f"ENSG00000{num_snps + gene_idx}" - for _ in range(num_snps_gene): - # Ensure unique variant_id - while True: - pos = np.random.randint(1, num_snps) - a1 = np.random.choice(['A', 'T', 'C', 'G']) - a2 = np.random.choice(['A', 'T', 'C', 'G']) - while a1==a2: - a1 = np.random.choice(['A', 'T', 'C', 'G']) - a2 = np.random.choice(['A', 'T', 'C', 'G']) - - variant_id = f"chr20:{pos}:{a1}:{a2}" - variant_reverse_id = f"chr20:{pos}:{a2}:{a1}" - - if variant_id not in generated_variant_ids and variant_reverse_id not in generated_variant_ids: - generated_variant_ids.add(variant_id) - generated_variant_ids.add(variant_reverse_id) - break - - - # Generate other columns with dummy data - start_distance = np.random.randint(-500000, 500000) - a1s.append(a1) - a2s.append(a2) - af = np.random.uniform(0, 1) - ma_sample = np.random.randint(50, 200) - ma_count = np.random.randint(50, 300) - pval_nominal = np.random.uniform(0, 1) - slope = np.random.uniform(-1, 1) - slope_se = np.random.uniform(0.001, 1) - - # Append data to lists - gene_ids.append(phenotype_id) - variant_ids.append(variant_id) - start_distances.append(start_distance) - afs.append(af) - positions.append(pos) - ma_samples.append(ma_sample) - ma_counts.append(ma_count) - pval_nominals.append(pval_nominal) - slopes.append(slope) - slope_ses.append(slope_se) - - # Create a DataFrame - data = { - "Chr":20, - "Gene":gene_ids, - "cell.type": "Tgd", - "pos": positions, - "a0":a1, - "a1":a2, - "SNP": variant_ids, - "START": start_distances, - "EAF": afs, - "p": pval_nominals, - "beta": slopes, - "se": slope_ses - } - - df = pd.DataFrame(data) - - # Save to a CSV file - df.to_csv(f"{out_csv}_{phenotype_id}.tsv.gz", index=False, sep="\t", compression="gzip") - - print(f"Dummy data file created: {out_csv}") - -if __name__ == '__main__': - create_dummy_data() + phenotype_id, rows = _generate_one_gene_rows( + rng, num_snps, num_snps_gene, gene_idx, generated_variant_ids + ) + + gz_path = f"{out_csv}_{phenotype_id}.tsv.gz" + with gzip.open(gz_path, "wt", encoding="utf-8", newline="") as gz_f: + w = csv.DictWriter(gz_f, fieldnames=_HEADER, delimiter="\t", lineterminator="\n") + w.writeheader() + w.writerows(rows) + print(f"Dummy data file created: {gz_path}") + + if also_tsv: + tsv_path = f"{out_csv}_{phenotype_id}.tsv" + with open(tsv_path, "w", encoding="utf-8", newline="") as tsv_f: + w = csv.DictWriter(tsv_f, fieldnames=_HEADER, delimiter="\t", lineterminator="\n") + w.writeheader() + w.writerows(rows) + print(f"Uncompressed copy: {tsv_path}") + + +def _parse_args() -> argparse.Namespace: + """Parse CLI arguments for the dummy-data generator.""" + p = argparse.ArgumentParser(description="Generate two dummy QTL TSVs (random A/T/C/G alleles per row).") + p.add_argument("--num_snps", type=int, default=10000, help="Upper bound for random POS (exclusive)") + p.add_argument("--num_snps_gene", type=int, default=2000, help="SNPs per gene file") + p.add_argument("--out_csv", type=str, default="dummy_out", help="Output prefix") + p.add_argument("--seed", type=int, default=None, help="RNG seed (reproducible runs)") + p.add_argument("--also-tsv", action="store_true", help="Also write uncompressed .tsv files") + return p.parse_args() + + +if __name__ == "__main__": + args = _parse_args() + create_dummy_data( + num_snps=args.num_snps, + num_snps_gene=args.num_snps_gene, + out_csv=args.out_csv, + seed=args.seed, + also_tsv=args.also_tsv, + ) diff --git a/tdbsumstat/utils/create_metadata.py b/tdbsumstat/utils/create_metadata.py index 8c93977..4433b9e 100755 --- a/tdbsumstat/utils/create_metadata.py +++ b/tdbsumstat/utils/create_metadata.py @@ -1,69 +1,2 @@ -import json -from collections import defaultdict -input_path = "/lustre/scratch124/humgen/projects_v2/cardinal_analysis/analysis/core_dataset/freeze3/tiledbs/Tensor/TileDB_f3_UKB_cis_t2_metadata.json" -output_path = input_path.replace(".json", "_fixed.json") - -objs = [] -with open(input_path) as f: - text = f.read() - -decoder = json.JSONDecoder() -idx = 0 -while idx < len(text): - obj, idx = decoder.raw_decode(text, idx) - objs.append(obj) - -with open(output_path, "w") as f: - json.dump(objs, f, indent=2) - -print(f"✅ Salvaged {len(objs)} metadata records into {output_path}") - - -fixed_path = "/lustre/scratch124/humgen/projects_v2/cardinal_analysis/analysis/core_dataset/freeze3/tiledbs/Tensor/TileDB_f3_UKB_cis_t2_metadata_fixed.json" -output_path = fixed_path.replace("_fixed.json", "_merged.json") - -with open(fixed_path) as f: - metadata_records = json.load(f) - -# Create a merged dictionary -merged_metadata = { - "file_path": [], - "trait": [], - "celltype": [] -} - -# For storing per-cell/chromosome info if present -cell_chrom_data = defaultdict(lambda: defaultdict(list)) - -for record in metadata_records: - # Merge file paths - if "file_path" in record and record["file_path"] not in merged_metadata["file_path"]: - merged_metadata["file_path"].append(record["file_path"]) - # Merge traits - if len(record["trait"]) > 0: - for t in record["trait"]: - if t not in merged_metadata["trait"]: - merged_metadata["trait"].append(t) - # Merge celltypes and their per-chromosome data - if len(record["celltype"]) > 0: - for cell in record["celltype"]: - if cell not in merged_metadata["celltype"]: - merged_metadata["celltype"].append(cell) - # Merge chromosome-level info if exists - if cell in record: - for chrom, genes in record[cell].items(): - cell_chrom_data[cell][chrom] = {} - #existing_genes = {g for g in cell_chrom_data[cell][chrom]} - for g in genes: - #if g not in existing_genes: - cell_chrom_data[cell][chrom][g] = genes[g] - -# Add per-cell/chromosome info -for cell, chrom_dict in cell_chrom_data.items(): - merged_metadata[cell] = chrom_dict - -# Save as a single JSON object -with open(output_path, "w") as f: - json.dump(merged_metadata, f, indent=2) - -print(f"✅ Merged metadata saved to {output_path}") +# This standalone script has been moved to the top-level scripts/ directory. +# See scripts/create_metadata.py for the current version. diff --git a/tdbsumstat/utils/fix_json.py b/tdbsumstat/utils/fix_json.py index ef83c6c..45b450f 100644 --- a/tdbsumstat/utils/fix_json.py +++ b/tdbsumstat/utils/fix_json.py @@ -1,55 +1,2 @@ -import json -import re -from collections import defaultdict - -# === STEP 1: Read the entire string from file === -with open("/project/cardinal/QTLs/freeze3/TileDBs/TileDB_metanalyses_gh_celltype2_freeze3_metadata.json", "r", encoding="utf-8") as f: - data_str = f.read() - -# === STEP 2: Split based on the start of each JSON fragment === -# We capture the first '{' before each file_path -fragments = re.findall(r'(\{[^{]*"file_path":.*?)(?=\{[^{]*"file_path":|\Z)', data_str, flags=re.S) - -print(f"🧩 Found {len(fragments)} fragments") - -# === STEP 3: Parse each fragment === -parsed_fragments = [] -for i, frag in enumerate(fragments): - try: - parsed_fragments.append(json.loads(frag)) - except json.JSONDecodeError as e: - print(f"⚠️ Fragment {i} failed to parse at char {e.pos}: {e}") - print(frag[:300] + "...") - # optional: skip or raise - continue - -# === STEP 4: Merge fragments as before === -merged = { - "trait": [], - "celltype": [], -} -celltype_data = defaultdict(lambda: defaultdict(dict)) - -for frag in parsed_fragments: - if "trait" in frag and isinstance(frag["trait"], list): - merged["trait"].extend(frag["trait"]) - if "celltype" in frag and isinstance(frag["celltype"], list): - merged["celltype"].extend(frag["celltype"]) - for key, val in frag.items(): - if key in ("trait", "celltype", "CELL", "file_path"): - continue - for num, genes in val.items(): - for gene_id, gene_data in genes.items(): - celltype_data[key][num][gene_id] = gene_data - -for celltype, numbers in celltype_data.items(): - merged[celltype] = numbers - -merged["trait"] = list(dict.fromkeys(merged["trait"])) -merged["celltype"] = list(dict.fromkeys(merged["celltype"])) - -# === STEP 5: Save merged JSON === -with open("metadata_merged.json", "w", encoding="utf-8") as out_f: - json.dump(merged, out_f, indent=2) - -print("✅ Merged JSON written to metadata_merged.json") +# This standalone script has been moved to the top-level scripts/ directory. +# See scripts/fix_json.py for the current version. diff --git a/tdbsumstat/utils/generate_table_cell_sumstat.py b/tdbsumstat/utils/generate_table_cell_sumstat.py index 43a4409..8104c4f 100755 --- a/tdbsumstat/utils/generate_table_cell_sumstat.py +++ b/tdbsumstat/utils/generate_table_cell_sumstat.py @@ -1,22 +1,2 @@ -import pandas as pd -import tiledb -rows = [] -tdb = tiledb.open('/lustre/scratch124/humgen/projects_v2/cardinal_analysis/analysis/core_dataset/freeze3/tiledbs/Tensor/TileDB_f3_UKB_cis_t2', 'w') -# Loop over all celltypes in metadata -for celltype in merged_metadata["celltype"]: - if celltype in merged_metadata: # make sure the key exists in dict - groups = merged_metadata[celltype] - for group, values in groups.items(): # e.g. group "11" - for gene_id in values: - rows.append({ - "CHR": group, - "CELL": celltype, - "GENE": gene_id, - "N": values[gene_id]["N"], - "ACAT": values[gene_id]["ACAT"], - "PHENOVAR": values[gene_id]["PHENO_VAR"], - }) -df = pd.DataFrame(rows) - -tdb.meta["metadata"] = json.dumps(merged_metadata) -df.to_csv("/lustre/scratch124/humgen/projects_v2/cardinal_analysis/analysis/core_dataset/freeze3/tiledbs/Tensor/Bangladeshi/metadata_gh_bangladeshi_f3_celltype1_acat.csv",index = False) \ No newline at end of file +# This standalone script has been moved to the top-level scripts/ directory. +# See scripts/generate_table_cell_sumstat.py for the current version. diff --git a/tdbsumstat/utils/harmonize_ingest.py b/tdbsumstat/utils/harmonize_ingest.py index ed55b5d..58891b0 100755 --- a/tdbsumstat/utils/harmonize_ingest.py +++ b/tdbsumstat/utils/harmonize_ingest.py @@ -1,674 +1,20 @@ -import logging -import json -from pathlib import Path -import os -import pandas as pd -import polars as pl -import numpy as np -from scipy import stats -import tiledb -import gwaslab as gl -from collections import defaultdict -from tdbsumstat.utils import acat_optimized, compute_pheno_variance - - -logger = logging.getLogger(__name__) -logging.basicConfig(level=logging.INFO, format="%(asctime)s - %(levelname)s - %(message)s") - - -class HarmonizationError(Exception): - """Custom exception for harmonization errors.""" - pass - - -class Harmonize: - def __init__(self, mapping_file: str, uri: str, type_sumstat: str, pvar_file: str, type_trait: str, mac: int, maf: float, permuted: bool): - self.mapping_file = mapping_file - self.uri = uri - self.pvar_file = pvar_file - self.type_sumstat = type_sumstat - self.type_trait = type_trait - self.mapping_types = {} - self.tiledb_types = {} - self.dimension_tiledb = [] - self.mac = mac - self.maf = maf - self.permuted = permuted - print(self.permuted) - - def create_mapping(self): - df = pd.read_csv(self.mapping_file, header=None, names=["key", "value"]) - if df.empty: - raise HarmonizationError("Mapping file is empty or not formatted correctly.") - self.mapping_types = dict(zip(df["key"], df["value"])) - #check that "BETA", "SE" are in the vlaues of the mapping_types - if not all(col in self.mapping_types.values() for col in ["BETA", "SE"]): - raise HarmonizationError("Mapping file must contain BETA and SE columns.") - # Check if CHR and POS or SNP are present - if not all(col for col in ["CHR", "POS"] if col in self.mapping_types.values()): - if "SNPID" not in self.mapping_types.values(): - raise HarmonizationError("Mapping file must contain either CHR, and POS or SNPID columns.") - - def create_tiledb(self): - """Create the mapping and dtype definitions.""" - pos_domain = (1, 300000000) # Example range for genomic positions - chr_domain = (1, 24) # Example range for genomic positions - attrs=[ - tiledb.Attr(name="SNPID", dtype="ascii", filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)])), - tiledb.Attr(name="RSID", dtype="ascii", filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)])), - tiledb.Attr(name="EAF", dtype=np.float32, filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)])), - tiledb.Attr(name="BETA", dtype=np.float32, filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)])), - tiledb.Attr(name="SE", dtype=np.float32, filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)])), - tiledb.Attr(name="P", dtype=np.float64, filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)])) - ] - - if self.type_sumstat == "gwas": - - self.dimension_tiledb = ["CHR", "TRAIT", "POS"] - dom = tiledb.Domain( - tiledb.Dim(name="CHR", domain = chr_domain, dtype=np.uint16, filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)])), - tiledb.Dim(name="TRAIT", dtype="ascii", var=True, filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)]) ), - tiledb.Dim(name="POS", domain = pos_domain, dtype=np.uint32, filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)])) - ) - else: - - self.dimension_tiledb = ["CHR", "CELL", "GENE", "POS"] - dom = tiledb.Domain( - tiledb.Dim(name="CHR", domain = chr_domain, dtype=np.uint16, filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)])), - tiledb.Dim(name="CELL", dtype="ascii", var=True, filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)]) ), - tiledb.Dim(name="GENE",dtype="ascii", var=True, filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)]) ), - tiledb.Dim(name="POS", domain = pos_domain, dtype=np.uint32, filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)])) - ) - - attrs = attrs + [ - tiledb.Attr(name="DIST", dtype=np.float32, filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)])) - ] - schema = tiledb.ArraySchema( - domain=dom, - attrs=attrs, - sparse=True, - allows_duplicates=False - ) - tiledb.Array.create(self.uri, schema) - - def align_alleles(self): - """Align alleles based on pvar file.""" - if not self.pvar_file: - raise HarmonizationError("pvar_file must be provided to verify alleles order") - if not Path(self.pvar_file).is_file(): - raise FileNotFoundError(f"pvar_file {self.pvar_file} does not exist") - - #The ALT must correspond to the alternative allele - pvar_df = pl.read_csv( - self.pvar_file, - separator="\t", - has_header=True, - dtypes={"CHROM": pl.Utf8, "POS": pl.Utf8, "SNPID": pl.Utf8, - "REF": pl.Utf8, "ALT": pl.Utf8}, - ) - #Here we assume the SNPID is alphabetically sortedin both pvar and summary statistics - self.chunk_pl = self.chunk_pl.join(pvar_df, on="SNPID", how="inner", suffix="_pvar") - - swap = pl.col("ALT")< pl.col("REF") - - self.chunk_pl = self.chunk_pl.with_columns([ - pl.when(swap).then(pl.col("BETA")).otherwise(-pl.col("BETA")), - pl.when(swap).then(pl.col("EAF")).otherwise(1.0-pl.col("EAF")) - ]) - - def harmonize(self, - sumstat, - trait: str = None, - cell: str = None, - gene: str = None, - pheno_var:int = None, - n: int = None, - n_controls: int = None, - n_cases: int = None): - """Load and rename columns, and ensure CHR/POS exist.""" - self.chunk_pl = sumstat.rename(self.mapping_types) - # If CHR/POS missing, extract from SNP ID - if "CHR" not in self.chunk_pl.columns or "POS" not in self.chunk_pl.columns: - self.chunk_pl = self.chunk_pl.with_columns( - pl.col("SNPID") - .str.split_exact(":", 4) - .struct.rename_fields(["CHR", "POS", "A1", "A2"]) - .alias("fields") - ).unnest("fields") - - if "SNPID" in self.chunk_pl.columns: - self.chunk_pl = self.chunk_pl.drop("SNPID") - if "EAF" not in self.chunk_pl.columns: - self.chunk_pl = self.chunk_pl.with_columns(pl.lit(0).alias("EAF")) - if "DIST" not in self.chunk_pl.columns: - self.chunk_pl = self.chunk_pl.with_columns(pl.lit(1).alias("DIST")) - - if self.maf is not None: - self.chunk_pl = self.chunk_pl.with_columns( - (pl.min_horizontal(pl.col("EAF"), 1 - pl.col("EAF"))) - .alias("MAF") - ).filter(pl.col("MAF") >= self.maf) - - if self.type_trait == "quant": - if not "N" in self.chunk_pl.columns: - if n is not None: - self.chunk_pl = self.chunk_pl.with_columns( - pl.lit(int(n)).alias("N") - ) - else: - raise HarmonizationError("N column is missing and N parameter is not provided") - if self.mac is not None: - self.chunk_pl = self.chunk_pl.with_columns( - (2 * pl.col("N") * pl.min_horizontal(pl.col("EAF"), 1 - pl.col("EAF"))) - .alias("MAC") - ).filter(pl.col("MAC") >= self.mac) - - self.chunk_pl = self.chunk_pl.with_columns( - pl.lit(pheno_var).alias("PHENO_VAR") - ) - elif self.type_trait == "binary": - if not all(sample_size in self.chunk_pl.columns for sample_size in ["N_CASES", "N_CONTROLS"]): - if not None in [n_cases, n_controls]: - self.chunk_pl = self.chunk_pl.with_columns( - pl.lit(float(n_cases)).alias("N_CASES"), - pl.lit(float(n_controls)).alias("N_CONTROLS"), - pl.lit(float(n_cases) + float(n_controls)).alias("N"), - ) - else: - raise HarmonizationError("n_cases and n_controls columns are missing and were not provided") - if self.mac is not None: - self.chunk_pl = self.chunk_pl.with_columns( - (2 * pl.col("N") * pl.min_horizontal(pl.col("EAF"), 1 - pl.col("EAF"))) - .alias("MAC") - ).filter(pl.col("MAC") >= self.mac) - else: - raise HarmonizationError("Type of trait must be either binary or quant") - - - - if "SNPID" in self.chunk_pl.columns: - self.chunk_pl = self.chunk_pl.drop("SNPID") - - - #Here we always assumbe that the SNPs are in REF=A1 and ALT=A2 - swap = pl.col("A1") < pl.col("A2") - - #Start by creating new SNPID aligned - self.chunk_pl = self.chunk_pl.with_columns([ - pl.when(swap).then(pl.col("A1")).otherwise(pl.col("A2")).alias("EA"), - # set NEA to the larger allele - pl.when(swap).then(pl.col("A2")).otherwise(pl.col("A1")).alias("NEA")] - ) - - self.chunk_pl = self.chunk_pl.with_columns( - pl.concat_str( - [ - pl.col("CHR"), - pl.col("POS").cast(pl.Utf8), # cast POS if numeric - pl.col("EA"), # lexicographically smaller - pl.col("NEA") # lexicographically larger - ], - separator=":" - ).alias("SNPID") - ) - - if self.pvar_file: - self.align_alleles() - self.chunk_pl.drop(["REF","ALT"]) - else: - # flip the sign of BETA when swapping - self.chunk_pl = self.chunk_pl.with_columns([ - pl.when(swap).then(-pl.col("BETA")).otherwise(pl.col("BETA")).alias("BETA"), - # flip EAF to 1 - EAF when swapping - pl.when(swap).then(1.0 - pl.col("EAF")).otherwise(pl.col("EAF")).alias("EAF"), - # set EA to the smaller allele - ]) - self.chunk_pl = self.chunk_pl.drop(["A1","A2"]) - - self.chunk_pl = self.chunk_pl.with_columns( - pl.concat_str( - pl.lit("chr"), - pl.col("SNPID")).alias("SNPID")) - - if self.type_sumstat=="gwas": - self.tiledb_types = { - "CHR": np.uint16, - "TRAIT": str, - "POS": np.uint32, - "SNPID": str, - "RSID": str, - "EAF": np.float32, - "BETA": np.float32, - "SE": np.float32, - "P": np.float64, - } - if "TRAIT" not in self.chunk_pl.columns: - self.chunk_pl = self.chunk_pl.with_columns( - pl.lit(trait).alias("TRAIT") - ) - else: - self.tiledb_types = { - "CHR": np.uint16, - "CELL": str, - "GENE": str, - "POS": np.uint32, - "SNPID": str, - "RSID": str, - "DIST": np.int64, - "EAF": np.float32, - "BETA": np.float32, - "SE": np.float32, - "P": np.float64, - } - if "CELL" not in self.chunk_pl.columns: - self.chunk_pl = self.chunk_pl.with_columns( - pl.lit(cell).alias("CELL") - ) - if "GENE" not in self.chunk_pl.columns: - self.chunk_pl = self.chunk_pl.with_columns( - pl.lit(gene).alias("GENE") - ) - if "RSID" not in self.chunk_pl.columns: - self.chunk_pl = self.chunk_pl.with_columns( - pl.lit("None").alias("RSID") - ) - if "LOG10P" in self.chunk_pl.columns: - self.chunk_pl = self.chunk_pl.with_columns( - (10 ** (-pl.col("LOG10P"))).alias("P") - ) - - - if self.permuted: - self.chunk_pl = self.chunk_pl.with_columns( - ( - pl.col("BETA").pow(2) / - pl.col("P").map_batches( - lambda x: pl.Series(stats.chi2.isf(x.to_numpy(), df=1)) - ) - ).sqrt().alias("SE")) - - else: - #Calculate p-value from z-score - self.chunk_pl = self.chunk_pl.drop('P') - self.chunk_pl = self.chunk_pl.with_columns( - (pl.col("BETA") / pl.col("SE")).pow(2).map_batches( - lambda x: pl.Series(stats.chi2.sf(x.to_numpy(), df=1)), - return_dtype=pl.Float64 - ).alias('P') - ) - - def qc_sumstat(self, file_path:str): - directory = self.uri + "_logs" - filename = os.path.basename(file_path) # "test.csv.gz" - # Remove all extensions - file_name = filename.split('.')[0] # "test" - - if not os.path.isdir(directory): - os.mkdir(directory) - sumstat_preqc = self.chunk_pl.to_pandas() - if self.type_sumstat == "gwas": - if self.type_trait== "quant": - sumstat_gl =gl.Sumstats(sumstat_preqc, - snpid="SNPID", - chrom="CHR", - pos="POS", - eaf="EAF", - beta="BETA", - se="SE", - p="P", - n="N", - ea = "EA", - nea = "NEA", - other = ["TRAIT","RSID"]) - else: - sumstat_gl =gl.Sumstats(sumstat_preqc, - snpid="SNPID", - chrom="CHR", - pos="POS", - eaf="EAF", - beta="BETA", - se="SE", - p="P", - n="N", - ncase = "N_CASES", - ncontrol = "N_CONTROLS", - ea = "EA", - nea = "NEA", - other = ["TRAIT","RSID"]) - - else: - sumstat_gl =gl.Sumstats(sumstat_preqc, - snpid="SNPID", - chrom="CHR", - pos="POS", - eaf="EAF", - beta="BETA", - se="SE", - p="P", - n="N", - other = ["CELL","GENE","RSID","DIST","PHENO_VAR"]) - #sumstat_gl.fix_id() - sumstat_gl.fix_chr(remove=True) - sumstat_gl.fix_pos(remove=True) - sumstat_gl.fix_allele(remove=True) - sumstat_gl.check_sanity() - sumstat_gl.check_data_consistency() - #sumstat_gl.remove_dup(mode="m") - #sumstat_gl.basic_check(n_cores = 4, remove=True, remove_dup=True) - - sumstat_gl.log.save(directory + "/" + file_name) - self.chunk_pl = pl.from_pandas(sumstat_gl.data) - - def ingest_data(self, file_path): - """Append harmonized data to TileDB.""" - pl.Config.set_tbl_cols(-1) - if self.type_sumstat == "gwas": - dedup_keys = ["CHR", "POS", "TRAIT"] - else: - dedup_keys = ["CHR", "POS", "CELL", "GENE"] - - # Option A (recommended): window count -> keep only rows whose group count == 1 - self.chunk_pl = ( - self.chunk_pl - .with_columns(pl.count().over(dedup_keys).alias("_grp_count")) - .filter(pl.col("_grp_count") == 1) - .drop("_grp_count") - ) - self.chunk_pl = self.chunk_pl.with_columns([ - pl.col("CHR").cast(pl.UInt16), - pl.col("POS").cast(pl.UInt32) - ]) - chunk_pl_ingest = self.chunk_pl.select(self.tiledb_types.keys()) - chunk_pl_ingest = chunk_pl_ingest.drop_nulls() - try: - tiledb.from_pandas( - uri=self.uri, - dataframe=chunk_pl_ingest.to_pandas(), - index_dims=self.dimension_tiledb, - column_types=self.tiledb_types, - allows_duplicates = False, - mode="append" - ) - logger.info(f"Successfully appended chunk to TileDB for file {file_path}") - except Exception as e: - logger.error(f"Failed to append chunk to TileDB for file {file_path}: {e}") - raise - - - def create_metadata(self, file_path: str): - """Create and store metadata as individual JSON files.""" - metadata = { - "traits": [], - "CELL": [] - } - self.chunk_pl = self.chunk_pl.select( - [col for col in self.chunk_pl.columns if self.chunk_pl[col].null_count() < self.chunk_pl.height] - ) - self.chunk_pl = self.chunk_pl.drop_nulls() - if self.type_sumstat == "qtl": - # Get unique cell types - celltypes = self.chunk_pl["CELL"].unique().to_list() - if not celltypes: - raise HarmonizationError("No cell types found in the data") - - # Update CELL list - metadata["CELL"] = celltypes - - # Process each cell type - for cell in celltypes: - # Filter by this cell type and compute ACAT per gene - df_cell = self.chunk_pl.filter(pl.col("CELL") == cell) - - # Group by CHR and GENE, compute ACAT for each group - chr_gene_agg = df_cell.group_by(["CHR", "GENE"]).agg([ - pl.col("P").map_batches( - lambda s: pl.Series([acat_optimized(s)]), - return_dtype=pl.Float64 - ).alias("ACAT_LIST"), - pl.col("P").min().alias("min_P"), - pl.col("N").first().alias("N"), - pl.col("PHENO_VAR").first().alias("PHENO_VAR") - ]) - chr_gene_agg = chr_gene_agg.with_columns( - pl.col("ACAT_LIST").list.first().alias("ACAT") - ) - - # Initialize cell structure if not exists - if cell not in metadata: - metadata[cell] = {} - - # Populate metadata with chromosome -> gene structure - for row in chr_gene_agg.iter_rows(named=True): - chrom = str(row["CHR"]) # Convert to string for consistency - gene = row["GENE"] - acat_val = row["ACAT"] - n_val = float(row["N"]) - min_p = float(row["min_P"]) - pheno_val = float(row["PHENO_VAR"]) - - if chrom not in metadata[cell]: - metadata[cell][chrom] = {} - - gene_metadata = { - "ACAT": float(acat_val), - "N": n_val, - "PHENO_VAR": pheno_val, - "MIN_P":min_p - } - - metadata[cell][chrom][gene] = gene_metadata - - else: # GWAS case - if "TRAIT" not in self.chunk_pl.columns: - raise HarmonizationError("TRAIT column is missing in the data") - - traits = self.chunk_pl["TRAIT"].unique().to_list() - metadata["traits"] = traits - - for trait in traits: - df_trait = self.chunk_pl.filter(pl.col("TRAIT") == trait) - pheno_var = compute_pheno_variance(df_trait, self.type_trait) - n_val = df_trait["N"].unique().to_list()[0] - min_p = df_trait["P"].min().to_list()[0] - - trait_metadata = { - "N": float(n_val), - "PHENO_VAR": float(pheno_var), - "MIN_P": float(min_p) - } - - if self.type_trait == "binary": - n_cases = df_trait["N_CASES"].unique().to_list()[0] - n_controls = df_trait["N_CONTROLS"].unique().to_list()[0] - trait_metadata.update({ - "N_CASES": float(n_cases), - "N_CONTROLS": float(n_controls) - }) - - metadata[trait] = trait_metadata - - # Write individual metadata file instead of updating TileDB - self._write_individual_metadata(metadata, file_path) - - logger.info(f"Individual metadata file created for {file_path}") - - def _write_individual_metadata(self, metadata, file_path): - """Write metadata to individual JSON file.""" - metadata_dir = f"{self.uri}_metadata_parts" - os.makedirs(metadata_dir, exist_ok=True) - - # Create a safe filename from the original file path - file_stem = Path(file_path).stem - metadata_file = os.path.join(metadata_dir, f"{file_stem}.json") - - with open(metadata_file, 'w') as f: - json.dump(metadata, f, indent=2) - - logger.info(f"Metadata written to {metadata_file}") - - def export_metadata_to_csv(self, output_path: str = None): - """Export metadata to CSV format.""" - if output_path is None: - output_path = f"{self.uri}_metadata.csv" - - # Get the merged metadata from TileDB - with tiledb.open(self.uri, "r") as array: - merged_metadata_json = array.meta.get("merged_metadata", "{}") - - if not merged_metadata_json: - logger.warning("No merged metadata found in TileDB array") - return - - merged_metadata = json.loads(merged_metadata_json) - - # Create rows for CSV - rows = [] - - # Process QTL data (cell types) - if "CELL" in merged_metadata and merged_metadata["CELL"]: - for cell_type in merged_metadata["CELL"]: - if cell_type in merged_metadata: - cell_data = merged_metadata[cell_type] - for chrom, genes in cell_data.items(): - for gene_id, gene_metadata in genes.items(): - row = { - "CHR": chrom, - "CELL": cell_type, - "GENE": gene_id, - "ACAT": gene_metadata.get("ACAT", ""), - "N": gene_metadata.get("N", ""), - "PHENO_VAR": gene_metadata.get("PHENO_VAR", ""), - "MIN_P": gene_metadata.get("MIN_P", "") - } - rows.append(row) - - # Process GWAS data (traits) - if "traits" in merged_metadata and merged_metadata["traits"]: - for trait in merged_metadata["traits"]: - if trait in merged_metadata: - trait_data = merged_metadata[trait] - row = { - "TRAIT": trait, - "N": trait_data.get("N", ""), - "PHENO_VAR": trait_data.get("PHENO_VAR", ""), - "MIN_P": trait_data.get("MIN_P", ""), - "N_CASES": trait_data.get("N_CASES", ""), - "N_CONTROLS": trait_data.get("N_CONTROLS", "") - } - rows.append(row) - - # Create DataFrame and save to CSV - if rows: - df = pd.DataFrame(rows) - - # Reorder columns for better readability - if "CELL" in df.columns: - # QTL format - column_order = ["CHR", "CELL", "GENE", "ACAT", "MIN_P", "N", "PHENO_VAR"] - # Only include columns that exist in the DataFrame - column_order = [col for col in column_order if col in df.columns] - df = df[column_order] - else: - # GWAS format - column_order = ["TRAIT", "N", "PHENO_VAR", "MIN_P", "N_CASES", "N_CONTROLS"] - column_order = [col for col in column_order if col in df.columns] - df = df[column_order] - - df.to_csv(output_path, index=False) - logger.info(f"Metadata exported to {output_path}") - - # Print summary - if "CELL" in df.columns: - logger.info(f"Exported {len(df)} gene-cell type combinations") - logger.info(f"Cell types: {df['CELL'].nunique()}") - logger.info(f"Genes: {df['GENE'].nunique()}") - logger.info(f"Chromosomes: {df['CHR'].nunique()}") - else: - logger.info(f"Exported {len(df)} traits") - - return df - else: - logger.warning("No metadata found to export") - return pd.DataFrame() - - def merge_metadata_files(self): - """Merge all individual metadata files into final TileDB metadata.""" - metadata_dir = f"{self.uri}_metadata_parts" - - if not os.path.exists(metadata_dir): - logger.warning(f"No metadata directory found at {metadata_dir}") - return - - merged_metadata = { - "traits": [], - "CELL": [] - } - - # Process all individual metadata files - metadata_files = list(Path(metadata_dir).glob("*.json")) - logger.info(f"Found {len(metadata_files)} metadata files to merge") - - for metadata_file in metadata_files: - try: - with open(metadata_file, 'r') as f: - file_metadata = json.load(f) - - # Merge traits (for GWAS) - if "traits" in file_metadata and file_metadata["traits"]: - current_traits = set(merged_metadata.get("traits", [])) - new_traits = set(file_metadata["traits"]) - merged_metadata["traits"] = list(current_traits.union(new_traits)) - - for trait in file_metadata["traits"]: - if trait in file_metadata: - if trait not in merged_metadata: - merged_metadata[trait] = file_metadata[trait] - else: - logger.warning(f"Trait {trait} already exists in metadata, overwriting") - merged_metadata[trait] = file_metadata[trait] - - # Merge CELL and cell metadata (for QTL) - if "CELL" in file_metadata and file_metadata["CELL"]: - current_cells = set(merged_metadata.get("CELL", [])) - new_cells = set(file_metadata["CELL"]) - merged_metadata["CELL"] = list(current_cells.union(new_cells)) - - for cell in file_metadata["CELL"]: - if cell in file_metadata: - if cell not in merged_metadata: - merged_metadata[cell] = {} - - for chrom, genes in file_metadata[cell].items(): - if chrom not in merged_metadata[cell]: - merged_metadata[cell][chrom] = {} - - for gene, gene_data in genes.items(): - if gene in merged_metadata[cell][chrom]: - logger.warning(f"Gene {gene} already exists in cell {cell} chromosome {chrom}, overwriting") - merged_metadata[cell][chrom][gene] = gene_data - - logger.info(f"Processed {metadata_file.name}") - - except Exception as e: - logger.error(f"Error processing metadata file {metadata_file}: {e}") - continue - - # Store the final merged metadata in TileDB - with tiledb.open(self.uri, "w") as array: - array.meta["merged_metadata"] = json.dumps(merged_metadata) - - # Export to CSV - self.export_metadata_to_csv() - - # Log summary - cell_count = len(merged_metadata.get("CELL", [])) - trait_count = len(merged_metadata.get("traits", [])) - - total_genes = 0 - for cell_type in merged_metadata.get("CELL", []): - if cell_type in merged_metadata: - for chrom_data in merged_metadata[cell_type].values(): - total_genes += len(chrom_data) - - logger.info(f"Final merged metadata: {cell_count} cell types, {trait_count} traits, {total_genes} total genes") - +"""Backward-compatibility shim. + +All ingestion logic has been moved to the +:mod:`tdbsumstat.utils.ingest` package, which is composed of focused +modules: + +* :mod:`tdbsumstat.utils.ingest.schema` – TileDB schema creation +* :mod:`tdbsumstat.utils.ingest.mapping` – column-mapping CSV parsing +* :mod:`tdbsumstat.utils.ingest.harmonize` – data normalisation +* :mod:`tdbsumstat.utils.ingest.qc` – optional gwaslab QC +* :mod:`tdbsumstat.utils.ingest.writer` – TileDB data writer +* :mod:`tdbsumstat.utils.ingest.metadata` – metadata management + +This file re-exports ``Harmonize`` and ``HarmonizationError`` so that +existing code that imports from ``tdbsumstat.utils.harmonize_ingest`` +continues to work without modification. +""" +from tdbsumstat.utils.ingest import Harmonize, HarmonizationError # noqa: F401 + +__all__ = ["Harmonize", "HarmonizationError"] diff --git a/tdbsumstat/utils/ingest/__init__.py b/tdbsumstat/utils/ingest/__init__.py new file mode 100644 index 0000000..4f7cd29 --- /dev/null +++ b/tdbsumstat/utils/ingest/__init__.py @@ -0,0 +1,92 @@ +"""Ingestion package for TileDB-sumstat. + +The ``Harmonize`` class is composed from focused mixin classes: + +* :class:`~tdbsumstat.utils.ingest.schema.SchemaMixin` – TileDB array creation +* :class:`~tdbsumstat.utils.ingest.mapping.MappingMixin` – column-mapping CSV parsing +* :class:`~tdbsumstat.utils.ingest.harmonize.HarmonizeMixin` – data normalisation +* :class:`~tdbsumstat.utils.ingest.qc.QCMixin` – optional gwaslab QC +* :class:`~tdbsumstat.utils.ingest.writer.WriterMixin` – TileDB data writer +* :class:`~tdbsumstat.utils.ingest.metadata.MetadataMixin` – metadata management +""" +import logging + +from tdbsumstat.utils.ingest.errors import HarmonizationError +from tdbsumstat.utils.ingest.harmonize import HarmonizeMixin +from tdbsumstat.utils.ingest.mapping import MappingMixin +from tdbsumstat.utils.ingest.metadata import MetadataMixin +from tdbsumstat.utils.ingest.qc import QCMixin +from tdbsumstat.utils.ingest.schema import SchemaMixin +from tdbsumstat.utils.ingest.writer import WriterMixin + +logger = logging.getLogger(__name__) + +__all__ = ["Harmonize", "HarmonizationError"] + + +class Harmonize(SchemaMixin, MappingMixin, HarmonizeMixin, QCMixin, WriterMixin, MetadataMixin): + """Pipeline class for harmonising and ingesting summary statistics into TileDB. + + Typical usage:: + + h = Harmonize(mapping_file="mapping.csv", uri="my_tiledb", + type_sumstat="qtl", pvar_file=None, + type_trait="quant", mac=None, maf=None, permuted=False) + + # One-time setup + h.create_tiledb() + h.create_mapping() + + # Per-file loop + for filepath, cell, gene in file_list: + sumstat = pl.read_csv(filepath, separator="\\t", null_values="NA") + h.harmonize(sumstat=sumstat, cell=cell, gene=gene, n=n, pheno_var=pheno_var) + h.ingest_data(file_path=filepath) + h.create_metadata(file_path=filepath) + + # Finalise + h.merge_metadata_files() + + Parameters + ---------- + mapping_file: + Path to a header-less CSV mapping source column names to TileDB names. + uri: + Path where the TileDB array is (or will be) stored. + type_sumstat: + ``"gwas"`` or ``"qtl"``. + pvar_file: + Optional path to a pvar file used to align alleles. + type_trait: + ``"quant"`` or ``"binary"`` (used for GWAS only). + mac: + Minimum minor allele count filter applied during harmonisation. + maf: + Minimum minor allele frequency filter applied during harmonisation. + permuted: + If ``True``, SE is derived from the permuted p-value rather than + being recalculated from BETA/SE. + """ + + def __init__( + self, + mapping_file: str, + uri: str, + type_sumstat: str, + pvar_file: str, + type_trait: str, + mac: int, + maf: float, + permuted: bool, + ) -> None: + self.mapping_file = mapping_file + self.uri = uri + self.pvar_file = pvar_file + self.type_sumstat = type_sumstat + self.type_trait = type_trait + self.mapping_types: dict = {} + self.tiledb_types: dict = {} + self.dimension_tiledb: list = [] + self.mac = mac + self.maf = maf + self.permuted = permuted diff --git a/tdbsumstat/utils/ingest/errors.py b/tdbsumstat/utils/ingest/errors.py new file mode 100644 index 0000000..bffac51 --- /dev/null +++ b/tdbsumstat/utils/ingest/errors.py @@ -0,0 +1,6 @@ +"""Custom exception types for the ingestion pipeline.""" + + +class HarmonizationError(Exception): + """Raised when data harmonization fails due to missing or invalid input.""" + pass diff --git a/tdbsumstat/utils/ingest/harmonize.py b/tdbsumstat/utils/ingest/harmonize.py new file mode 100644 index 0000000..90e6280 --- /dev/null +++ b/tdbsumstat/utils/ingest/harmonize.py @@ -0,0 +1,272 @@ +"""Data harmonization – column renaming, allele standardisation, p-value computation.""" +import logging +from pathlib import Path + +import numpy as np +import polars as pl +from scipy import stats + +logger = logging.getLogger(__name__) + + +class HarmonizeMixin: + """Mixin that normalises a summary statistics Polars DataFrame. + + After calling :meth:`harmonize`, the processed data is stored in + ``self.chunk_pl`` and column-type metadata is stored in + ``self.tiledb_types``. + """ + + # ------------------------------------------------------------------ + # Public API + # ------------------------------------------------------------------ + + def harmonize( + self, + sumstat: pl.DataFrame, + trait: str = None, + cell: str = None, + gene: str = None, + pheno_var: float = None, + n: int = None, + n_controls: int = None, + n_cases: int = None, + ) -> None: + """Rename columns, compute missing fields, and set TileDB types. + + Parameters + ---------- + sumstat: + Raw Polars DataFrame to harmonise. + trait: + Trait identifier (GWAS only). + cell: + Cell-type identifier (QTL only). + gene: + Gene identifier (QTL only). + pheno_var: + Phenotypic variance (quant trait). + n: + Sample size. + n_controls: + Number of controls (binary GWAS). + n_cases: + Number of cases (binary GWAS). + + Raises + ------ + HarmonizationError + When required columns are missing and cannot be inferred. + """ + from tdbsumstat.utils.ingest.errors import HarmonizationError + + self.chunk_pl = sumstat.rename(self.mapping_types) + + # Extract CHR/POS from SNPID if not present + if "CHR" not in self.chunk_pl.columns or "POS" not in self.chunk_pl.columns: + self.chunk_pl = self.chunk_pl.with_columns( + pl.col("SNPID") + .str.split_exact(":", 4) + .struct.rename_fields(["CHR", "POS", "A1", "A2"]) + .alias("fields") + ).unnest("fields") + + if "SNPID" in self.chunk_pl.columns: + self.chunk_pl = self.chunk_pl.drop("SNPID") + if "EAF" not in self.chunk_pl.columns: + self.chunk_pl = self.chunk_pl.with_columns(pl.lit(0).alias("EAF")) + if "DIST" not in self.chunk_pl.columns: + self.chunk_pl = self.chunk_pl.with_columns(pl.lit(1).alias("DIST")) + + # Optional MAF filter + if self.maf is not None: + self.chunk_pl = self.chunk_pl.with_columns( + pl.min_horizontal(pl.col("EAF"), 1 - pl.col("EAF")).alias("MAF") + ).filter(pl.col("MAF") >= self.maf) + + # Sample-size and phenotypic-variance handling + self._apply_sample_size(n, n_cases, n_controls, pheno_var) + + # Second SNPID-drop guard (in case rename created one) + if "SNPID" in self.chunk_pl.columns: + self.chunk_pl = self.chunk_pl.drop("SNPID") + + # Allele standardisation: A1 < A2 order + self._standardise_alleles() + + # Assign RSID placeholder if absent + if "RSID" not in self.chunk_pl.columns: + self.chunk_pl = self.chunk_pl.with_columns(pl.lit("None").alias("RSID")) + + # Convert LOG10P → P + if "LOG10P" in self.chunk_pl.columns: + self.chunk_pl = self.chunk_pl.with_columns( + (10 ** (-pl.col("LOG10P"))).alias("P") + ) + + # Compute / recalculate p-value + if self.permuted: + self.chunk_pl = self.chunk_pl.with_columns( + ( + pl.col("BETA").pow(2) + / pl.col("P").map_batches( + lambda x: pl.Series(stats.chi2.isf(x.to_numpy(), df=1)) + ) + ).sqrt().alias("SE") + ) + else: + self.chunk_pl = self.chunk_pl.drop("P") + self.chunk_pl = self.chunk_pl.with_columns( + (pl.col("BETA") / pl.col("SE")) + .pow(2) + .map_batches( + lambda x: pl.Series(stats.chi2.sf(x.to_numpy(), df=1)), + return_dtype=pl.Float64, + ) + .alias("P") + ) + + # Set dimension labels and TileDB type maps + self._set_tiledb_types(trait=trait, cell=cell, gene=gene) + + def align_alleles(self) -> None: + """Align effect/other alleles using an external pvar reference file. + + Requires ``self.pvar_file`` to be set and point to a valid file. + + Raises + ------ + HarmonizationError + If ``pvar_file`` is not provided. + FileNotFoundError + If the pvar file path does not exist. + """ + from tdbsumstat.utils.ingest.errors import HarmonizationError + + if not self.pvar_file: + raise HarmonizationError("pvar_file must be provided to verify alleles order") + if not Path(self.pvar_file).is_file(): + raise FileNotFoundError(f"pvar_file {self.pvar_file} does not exist") + + pvar_df = pl.read_csv( + self.pvar_file, + separator="\t", + has_header=True, + schema_overrides={"CHROM": pl.Utf8, "POS": pl.Utf8, "SNPID": pl.Utf8, + "REF": pl.Utf8, "ALT": pl.Utf8}, + ) + self.chunk_pl = self.chunk_pl.join(pvar_df, on="SNPID", how="inner", suffix="_pvar") + + swap = pl.col("ALT") < pl.col("REF") + self.chunk_pl = self.chunk_pl.with_columns([ + pl.when(swap).then(pl.col("BETA")).otherwise(-pl.col("BETA")), + pl.when(swap).then(pl.col("EAF")).otherwise(1.0 - pl.col("EAF")), + ]) + + # ------------------------------------------------------------------ + # Private helpers + # ------------------------------------------------------------------ + + def _apply_sample_size(self, n, n_cases, n_controls, pheno_var): + """Add N, N_CASES, N_CONTROLS columns and apply MAC filter.""" + from tdbsumstat.utils.ingest.errors import HarmonizationError + + if self.type_trait == "quant": + if "N" not in self.chunk_pl.columns: + if n is not None: + self.chunk_pl = self.chunk_pl.with_columns(pl.lit(int(n)).alias("N")) + else: + raise HarmonizationError("N column is missing and N parameter is not provided") + if self.mac is not None: + self.chunk_pl = self.chunk_pl.with_columns( + (2 * pl.col("N") * pl.min_horizontal(pl.col("EAF"), 1 - pl.col("EAF"))).alias("MAC") + ).filter(pl.col("MAC") >= self.mac) + self.chunk_pl = self.chunk_pl.with_columns(pl.lit(pheno_var).alias("PHENO_VAR")) + + elif self.type_trait == "binary": + if not all(col in self.chunk_pl.columns for col in ["N_CASES", "N_CONTROLS"]): + if n_cases is not None and n_controls is not None: + self.chunk_pl = self.chunk_pl.with_columns( + pl.lit(float(n_cases)).alias("N_CASES"), + pl.lit(float(n_controls)).alias("N_CONTROLS"), + pl.lit(float(n_cases) + float(n_controls)).alias("N"), + ) + else: + raise HarmonizationError("n_cases and n_controls columns are missing and were not provided") + if self.mac is not None: + self.chunk_pl = self.chunk_pl.with_columns( + (2 * pl.col("N") * pl.min_horizontal(pl.col("EAF"), 1 - pl.col("EAF"))).alias("MAC") + ).filter(pl.col("MAC") >= self.mac) + else: + from tdbsumstat.utils.ingest.errors import HarmonizationError + raise HarmonizationError("Type of trait must be either binary or quant") + + def _standardise_alleles(self): + """Sort A1/A2 lexicographically; flip BETA and EAF when swapped.""" + swap = pl.col("A1") < pl.col("A2") + + self.chunk_pl = self.chunk_pl.with_columns([ + pl.when(swap).then(pl.col("A1")).otherwise(pl.col("A2")).alias("EA"), + pl.when(swap).then(pl.col("A2")).otherwise(pl.col("A1")).alias("NEA"), + ]) + + self.chunk_pl = self.chunk_pl.with_columns( + pl.concat_str( + [ + pl.col("CHR"), + pl.col("POS").cast(pl.Utf8), + pl.col("EA"), + pl.col("NEA"), + ], + separator=":", + ).alias("SNPID") + ) + + if self.pvar_file: + self.align_alleles() + self.chunk_pl = self.chunk_pl.drop(["REF", "ALT"]) + else: + self.chunk_pl = self.chunk_pl.with_columns([ + pl.when(swap).then(-pl.col("BETA")).otherwise(pl.col("BETA")).alias("BETA"), + pl.when(swap).then(1.0 - pl.col("EAF")).otherwise(pl.col("EAF")).alias("EAF"), + ]) + + self.chunk_pl = self.chunk_pl.drop(["A1", "A2"]) + self.chunk_pl = self.chunk_pl.with_columns( + pl.concat_str(pl.lit("chr"), pl.col("SNPID")).alias("SNPID") + ) + + def _set_tiledb_types(self, trait, cell, gene): + """Populate ``self.tiledb_types`` and add dimension columns.""" + if self.type_sumstat == "gwas": + self.tiledb_types = { + "CHR": np.uint16, + "TRAIT": str, + "POS": np.uint32, + "SNPID": str, + "RSID": str, + "EAF": np.float32, + "BETA": np.float32, + "SE": np.float32, + "P": np.float64, + } + if "TRAIT" not in self.chunk_pl.columns: + self.chunk_pl = self.chunk_pl.with_columns(pl.lit(trait).alias("TRAIT")) + else: + self.tiledb_types = { + "CHR": np.uint16, + "CELL": str, + "GENE": str, + "POS": np.uint32, + "SNPID": str, + "RSID": str, + "DIST": np.int64, + "EAF": np.float32, + "BETA": np.float32, + "SE": np.float32, + "P": np.float64, + } + if "CELL" not in self.chunk_pl.columns: + self.chunk_pl = self.chunk_pl.with_columns(pl.lit(cell).alias("CELL")) + if "GENE" not in self.chunk_pl.columns: + self.chunk_pl = self.chunk_pl.with_columns(pl.lit(gene).alias("GENE")) diff --git a/tdbsumstat/utils/ingest/mapping.py b/tdbsumstat/utils/ingest/mapping.py new file mode 100644 index 0000000..7b6df0d --- /dev/null +++ b/tdbsumstat/utils/ingest/mapping.py @@ -0,0 +1,41 @@ +"""Column-mapping utilities for summary statistics ingestion.""" +import logging + +import pandas as pd + +logger = logging.getLogger(__name__) + + +class MappingMixin: + """Mixin that parses and validates the column-mapping CSV file.""" + + def create_mapping(self) -> None: + """Load the mapping file and populate ``self.mapping_types``. + + The mapping file is a header-less CSV with two columns: + ``source_column_name, target_column_name``. + + Required target columns: ``BETA``, ``SE``. + Required targets for position: either ``CHR`` + ``POS``, or ``SNPID``. + + Raises + ------ + HarmonizationError + If the file is empty, or required columns are missing. + """ + from tdbsumstat.utils.ingest.errors import HarmonizationError + + df = pd.read_csv(self.mapping_file, header=None, names=["key", "value"]) + if df.empty: + raise HarmonizationError("Mapping file is empty or not formatted correctly.") + + self.mapping_types = dict(zip(df["key"], df["value"])) + + if not all(col in self.mapping_types.values() for col in ["BETA", "SE"]): + raise HarmonizationError("Mapping file must contain BETA and SE columns.") + + if not all(col in self.mapping_types.values() for col in ["CHR", "POS"]): + if "SNPID" not in self.mapping_types.values(): + raise HarmonizationError("Mapping file must contain either CHR, and POS or SNPID columns.") + + logger.info("Column mapping loaded: %d column(s) mapped", len(self.mapping_types)) diff --git a/tdbsumstat/utils/ingest/metadata.py b/tdbsumstat/utils/ingest/metadata.py new file mode 100644 index 0000000..a90086b --- /dev/null +++ b/tdbsumstat/utils/ingest/metadata.py @@ -0,0 +1,284 @@ +"""Metadata creation, export and merging for the ingestion pipeline.""" +import json +import logging +import os +from pathlib import Path + +import pandas as pd +import polars as pl +import tiledb + +from tdbsumstat.utils import acat_optimized, compute_pheno_variance + +logger = logging.getLogger(__name__) + + +class MetadataMixin: + """Mixin that handles per-file and merged TileDB metadata.""" + + # ------------------------------------------------------------------ + # Per-file metadata + # ------------------------------------------------------------------ + + def create_metadata(self, file_path: str) -> None: + """Compute summary statistics and write a per-file JSON metadata fragment. + + The fragment is saved under ``{self.uri}_metadata_parts/``. + + Parameters + ---------- + file_path: + Original file path; used to derive the metadata filename. + """ + from tdbsumstat.utils.ingest.errors import HarmonizationError + + metadata: dict = {"traits": [], "CELL": []} + + # Drop fully-null columns, then drop null rows + self.chunk_pl = self.chunk_pl.select( + [col for col in self.chunk_pl.columns if self.chunk_pl[col].null_count() < self.chunk_pl.height] + ) + self.chunk_pl = self.chunk_pl.drop_nulls() + + if self.type_sumstat == "qtl": + metadata = self._build_qtl_metadata(metadata) + else: + metadata = self._build_gwas_metadata(metadata) + + self._write_individual_metadata(metadata, file_path) + logger.info("Individual metadata file created for %s", file_path) + + def _build_qtl_metadata(self, metadata: dict) -> dict: + """Populate *metadata* with per-cell-type, per-gene statistics.""" + from tdbsumstat.utils.ingest.errors import HarmonizationError + + celltypes = self.chunk_pl["CELL"].unique().to_list() + if not celltypes: + raise HarmonizationError("No cell types found in the data") + + metadata["CELL"] = celltypes + + for cell in celltypes: + df_cell = self.chunk_pl.filter(pl.col("CELL") == cell) + + chr_gene_agg = df_cell.group_by(["CHR", "GENE"]).agg([ + pl.col("P").map_batches( + lambda s: pl.Series([acat_optimized(s)]), + return_dtype=pl.Float64, + ).alias("ACAT_LIST"), + pl.col("P").min().alias("min_P"), + pl.col("N").first().alias("N"), + pl.col("PHENO_VAR").first().alias("PHENO_VAR"), + ]) + chr_gene_agg = chr_gene_agg.with_columns( + pl.col("ACAT_LIST").list.first().alias("ACAT") + ) + + if cell not in metadata: + metadata[cell] = {} + + for row in chr_gene_agg.iter_rows(named=True): + chrom = str(row["CHR"]) + gene = row["GENE"] + metadata[cell].setdefault(chrom, {}) + metadata[cell][chrom][gene] = { + "ACAT": float(row["ACAT"]), + "N": float(row["N"]), + "PHENO_VAR": float(row["PHENO_VAR"]), + "MIN_P": float(row["min_P"]), + } + + return metadata + + def _build_gwas_metadata(self, metadata: dict) -> dict: + """Populate *metadata* with per-trait statistics.""" + from tdbsumstat.utils.ingest.errors import HarmonizationError + + if "TRAIT" not in self.chunk_pl.columns: + raise HarmonizationError("TRAIT column is missing in the data") + + traits = self.chunk_pl["TRAIT"].unique().to_list() + metadata["traits"] = traits + + for trait in traits: + df_trait = self.chunk_pl.filter(pl.col("TRAIT") == trait) + pheno_var = compute_pheno_variance(df_trait, self.type_trait) + n_val = df_trait["N"].unique().to_list()[0] + min_p = df_trait["P"].min().to_list()[0] + + trait_metadata: dict = { + "N": float(n_val), + "PHENO_VAR": float(pheno_var), + "MIN_P": float(min_p), + } + + if self.type_trait == "binary": + trait_metadata["N_CASES"] = float(df_trait["N_CASES"].unique().to_list()[0]) + trait_metadata["N_CONTROLS"] = float(df_trait["N_CONTROLS"].unique().to_list()[0]) + + metadata[trait] = trait_metadata + + return metadata + + def _write_individual_metadata(self, metadata: dict, file_path: str) -> None: + """Persist a metadata dict as a JSON fragment under the metadata_parts dir.""" + metadata_dir = f"{self.uri}_metadata_parts" + os.makedirs(metadata_dir, exist_ok=True) + + file_stem = Path(file_path).stem + metadata_file = os.path.join(metadata_dir, f"{file_stem}.json") + + with open(metadata_file, "w") as fh: + json.dump(metadata, fh, indent=2) + + logger.info("Metadata written to %s", metadata_file) + + # ------------------------------------------------------------------ + # Metadata export + # ------------------------------------------------------------------ + + def export_metadata_to_csv(self, output_path: str = None) -> pd.DataFrame: + """Export the merged TileDB metadata to a CSV file. + + Parameters + ---------- + output_path: + Destination path. Defaults to ``{self.uri}_metadata.csv``. + + Returns + ------- + pd.DataFrame + The exported metadata as a DataFrame (empty if nothing found). + """ + if output_path is None: + output_path = f"{self.uri}_metadata.csv" + + with tiledb.open(self.uri, "r") as array: + merged_metadata_json = array.meta.get("merged_metadata", "{}") + + if not merged_metadata_json: + logger.warning("No merged metadata found in TileDB array") + return pd.DataFrame() + + merged_metadata = json.loads(merged_metadata_json) + rows = [] + + # QTL data + for cell_type in merged_metadata.get("CELL", []): + cell_data = merged_metadata.get(cell_type, {}) + for chrom, genes in cell_data.items(): + for gene_id, gm in genes.items(): + rows.append({ + "CHR": chrom, "CELL": cell_type, "GENE": gene_id, + "ACAT": gm.get("ACAT", ""), + "N": gm.get("N", ""), + "PHENO_VAR": gm.get("PHENO_VAR", ""), + "MIN_P": gm.get("MIN_P", ""), + }) + + # GWAS data + for trait in merged_metadata.get("traits", []): + td = merged_metadata.get(trait, {}) + rows.append({ + "TRAIT": trait, + "N": td.get("N", ""), + "PHENO_VAR": td.get("PHENO_VAR", ""), + "MIN_P": td.get("MIN_P", ""), + "N_CASES": td.get("N_CASES", ""), + "N_CONTROLS": td.get("N_CONTROLS", ""), + }) + + if not rows: + logger.warning("No metadata found to export") + return pd.DataFrame() + + df = pd.DataFrame(rows) + + if "CELL" in df.columns: + col_order = [c for c in ["CHR", "CELL", "GENE", "ACAT", "MIN_P", "N", "PHENO_VAR"] if c in df.columns] + else: + col_order = [c for c in ["TRAIT", "N", "PHENO_VAR", "MIN_P", "N_CASES", "N_CONTROLS"] if c in df.columns] + + df = df[col_order] + df.to_csv(output_path, index=False) + logger.info("Metadata exported to %s", output_path) + return df + + # ------------------------------------------------------------------ + # Merge all per-file fragments into final TileDB metadata + # ------------------------------------------------------------------ + + def merge_metadata_files(self) -> None: + """Merge all per-file JSON fragments and store in TileDB. + + Reads every ``*.json`` from ``{self.uri}_metadata_parts/``, + merges them into a single dict, stores it in ``TileDB.meta`` + under the key ``merged_metadata``, and also exports a CSV. + """ + metadata_dir = f"{self.uri}_metadata_parts" + + if not os.path.exists(metadata_dir): + logger.warning("No metadata directory found at %s", metadata_dir) + return + + merged_metadata: dict = {"traits": [], "CELL": []} + + metadata_files = list(Path(metadata_dir).glob("*.json")) + logger.info("Found %d metadata file(s) to merge", len(metadata_files)) + + for metadata_file in metadata_files: + try: + with open(metadata_file, "r") as fh: + file_metadata = json.load(fh) + self._merge_single_metadata(merged_metadata, file_metadata) + logger.info("Processed %s", metadata_file.name) + except Exception as exc: + logger.error("Error processing metadata file %s: %s", metadata_file, exc) + continue + + with tiledb.open(self.uri, "w") as array: + array.meta["merged_metadata"] = json.dumps(merged_metadata) + + self.export_metadata_to_csv() + + cell_count = len(merged_metadata.get("CELL", [])) + trait_count = len(merged_metadata.get("traits", [])) + total_genes = sum( + len(chrom_data) + for cell_type in merged_metadata.get("CELL", []) + for chrom_data in merged_metadata.get(cell_type, {}).values() + ) + logger.info( + "Final merged metadata: %d cell type(s), %d trait(s), %d total gene(s)", + cell_count, trait_count, total_genes, + ) + + @staticmethod + def _merge_single_metadata(merged: dict, file_meta: dict) -> None: + """Merge one file_meta fragment into *merged* in-place.""" + # GWAS traits + if file_meta.get("traits"): + existing = set(merged.get("traits", [])) + merged["traits"] = list(existing.union(set(file_meta["traits"]))) + for trait in file_meta["traits"]: + if trait in file_meta: + if trait in merged: + logger.warning("Trait %s already exists – overwriting", trait) + merged[trait] = file_meta[trait] + + # QTL cell types + if file_meta.get("CELL"): + existing = set(merged.get("CELL", [])) + merged["CELL"] = list(existing.union(set(file_meta["CELL"]))) + for cell in file_meta["CELL"]: + if cell in file_meta: + merged.setdefault(cell, {}) + for chrom, genes in file_meta[cell].items(): + merged[cell].setdefault(chrom, {}) + for gene, gene_data in genes.items(): + if gene in merged[cell][chrom]: + logger.warning( + "Gene %s in cell %s chr %s already exists – overwriting", + gene, cell, chrom, + ) + merged[cell][chrom][gene] = gene_data diff --git a/tdbsumstat/utils/ingest/qc.py b/tdbsumstat/utils/ingest/qc.py new file mode 100644 index 0000000..ed08a9a --- /dev/null +++ b/tdbsumstat/utils/ingest/qc.py @@ -0,0 +1,69 @@ +"""GWAS-lab quality-control step (optional).""" +import logging +import os + +import polars as pl + +logger = logging.getLogger(__name__) + + +class QCMixin: + """Mixin that provides optional gwaslab-based QC on ``self.chunk_pl``.""" + + def qc_sumstat(self, file_path: str) -> None: + """Run gwaslab QC checks on the harmonised data in ``self.chunk_pl``. + + Logs are saved to ``{self.uri}_logs/{file_stem}.log``. + On success, ``self.chunk_pl`` is replaced with the QC-filtered + gwaslab DataFrame (converted back to Polars). + + Parameters + ---------- + file_path: + Original file path; used only to derive a log file name. + """ + import gwaslab as gl + + directory = self.uri + "_logs" + filename = os.path.basename(file_path) + file_name = filename.split(".")[0] + + os.makedirs(directory, exist_ok=True) + + sumstat_preqc = self.chunk_pl.to_pandas() + + if self.type_sumstat == "gwas": + if self.type_trait == "quant": + sumstat_gl = gl.Sumstats( + sumstat_preqc, + snpid="SNPID", chrom="CHR", pos="POS", + eaf="EAF", beta="BETA", se="SE", p="P", n="N", + ea="EA", nea="NEA", + other=["TRAIT", "RSID"], + ) + else: + sumstat_gl = gl.Sumstats( + sumstat_preqc, + snpid="SNPID", chrom="CHR", pos="POS", + eaf="EAF", beta="BETA", se="SE", p="P", n="N", + ncase="N_CASES", ncontrol="N_CONTROLS", + ea="EA", nea="NEA", + other=["TRAIT", "RSID"], + ) + else: + sumstat_gl = gl.Sumstats( + sumstat_preqc, + snpid="SNPID", chrom="CHR", pos="POS", + eaf="EAF", beta="BETA", se="SE", p="P", n="N", + other=["CELL", "GENE", "RSID", "DIST", "PHENO_VAR"], + ) + + sumstat_gl.fix_chr(remove=True) + sumstat_gl.fix_pos(remove=True) + sumstat_gl.fix_allele(remove=True) + sumstat_gl.check_sanity() + sumstat_gl.check_data_consistency() + + sumstat_gl.log.save(os.path.join(directory, file_name)) + self.chunk_pl = pl.from_pandas(sumstat_gl.data) + logger.info("QC completed for %s", file_path) diff --git a/tdbsumstat/utils/ingest/schema.py b/tdbsumstat/utils/ingest/schema.py new file mode 100644 index 0000000..cff4149 --- /dev/null +++ b/tdbsumstat/utils/ingest/schema.py @@ -0,0 +1,80 @@ +"""TileDB array schema creation for summary statistics ingestion.""" +import logging + +import numpy as np +import tiledb + +logger = logging.getLogger(__name__) + + +class SchemaMixin: + """Mixin that provides TileDB array schema creation.""" + + def create_tiledb(self) -> None: + """Create the TileDB array with the appropriate schema. + + The schema varies by ``self.type_sumstat``: + + * ``"gwas"`` – dimensions: CHR, TRAIT, POS + * ``"qtl"`` – dimensions: CHR, CELL, GENE, POS (+ DIST attribute) + """ + pos_domain = (1, 300_000_000) + chr_domain = (1, 24) + + attrs = [ + tiledb.Attr(name="SNPID", dtype="ascii", filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)])), + tiledb.Attr(name="RSID", dtype="ascii", filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)])), + tiledb.Attr(name="EAF", dtype=np.float32, filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)])), + tiledb.Attr(name="BETA", dtype=np.float32, filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)])), + tiledb.Attr(name="SE", dtype=np.float32, filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)])), + tiledb.Attr(name="P", dtype=np.float64, filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)])), + ] + + if self.type_sumstat == "gwas": + self.dimension_tiledb = ["CHR", "TRAIT", "POS"] + dom = tiledb.Domain( + tiledb.Dim( + name="CHR", domain=chr_domain, dtype=np.uint16, + filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)]), + ), + tiledb.Dim( + name="TRAIT", dtype="ascii", var=True, + filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)]), + ), + tiledb.Dim( + name="POS", domain=pos_domain, dtype=np.uint32, + filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)]), + ), + ) + else: + self.dimension_tiledb = ["CHR", "CELL", "GENE", "POS"] + dom = tiledb.Domain( + tiledb.Dim( + name="CHR", domain=chr_domain, dtype=np.uint16, + filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)]), + ), + tiledb.Dim( + name="CELL", dtype="ascii", var=True, + filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)]), + ), + tiledb.Dim( + name="GENE", dtype="ascii", var=True, + filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)]), + ), + tiledb.Dim( + name="POS", domain=pos_domain, dtype=np.uint32, + filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)]), + ), + ) + attrs = attrs + [ + tiledb.Attr(name="DIST", dtype=np.float32, filters=tiledb.FilterList([tiledb.ZstdFilter(level=5)])), + ] + + schema = tiledb.ArraySchema( + domain=dom, + attrs=attrs, + sparse=True, + allows_duplicates=False, + ) + tiledb.Array.create(self.uri, schema) + logger.info("TileDB array created at %s (type_sumstat=%s)", self.uri, self.type_sumstat) diff --git a/tdbsumstat/utils/ingest/writer.py b/tdbsumstat/utils/ingest/writer.py new file mode 100644 index 0000000..04790da --- /dev/null +++ b/tdbsumstat/utils/ingest/writer.py @@ -0,0 +1,61 @@ +"""TileDB data writer – appends harmonised data to an existing TileDB array.""" +import logging + +import polars as pl +import tiledb + +logger = logging.getLogger(__name__) + + +class WriterMixin: + """Mixin that deduplicates and writes ``self.chunk_pl`` into TileDB.""" + + def ingest_data(self, file_path: str) -> None: + """Deduplicate and append ``self.chunk_pl`` to the TileDB array. + + Rows with duplicate index-dimension keys are removed before writing. + Only the columns declared in ``self.tiledb_types`` are written. + + Parameters + ---------- + file_path: + Original file path; used only for logging messages. + + Raises + ------ + Exception + Re-raises any exception from ``tiledb.from_pandas``. + """ + pl.Config.set_tbl_cols(-1) + + dedup_keys = ["CHR", "POS", "TRAIT"] if self.type_sumstat == "gwas" else ["CHR", "POS", "CELL", "GENE"] + + # Drop ALL rows that share an index key with at least one other row. + # Rows with ambiguous (duplicated) positions are treated as unreliable + # and excluded from the TileDB write entirely. + self.chunk_pl = ( + self.chunk_pl + .with_columns(pl.len().over(dedup_keys).alias("_grp_count")) + .filter(pl.col("_grp_count") == 1) + .drop("_grp_count") + ) + self.chunk_pl = self.chunk_pl.with_columns([ + pl.col("CHR").cast(pl.UInt16), + pl.col("POS").cast(pl.UInt32), + ]) + + chunk_pl_ingest = self.chunk_pl.select(self.tiledb_types.keys()).drop_nulls() + + try: + tiledb.from_pandas( + uri=self.uri, + dataframe=chunk_pl_ingest.to_pandas(), + index_dims=self.dimension_tiledb, + column_types=self.tiledb_types, + allows_duplicates=False, + mode="append", + ) + logger.info("Successfully appended chunk to TileDB for file %s", file_path) + except Exception as exc: + logger.error("Failed to append chunk to TileDB for file %s: %s", file_path, exc) + raise diff --git a/tests/__init__.py b/tests/__init__.py new file mode 100644 index 0000000..e69de29 diff --git a/tests/conftest.py b/tests/conftest.py new file mode 100644 index 0000000..6b8109b --- /dev/null +++ b/tests/conftest.py @@ -0,0 +1,88 @@ +"""Pytest fixtures shared across the test suite.""" +import os +import tempfile + +import numpy as np +import pandas as pd +import polars as pl +import pytest +import tiledb + +EXAMPLE_DATA_DIR = os.path.join(os.path.dirname(__file__), "..", "example_data") + + +@pytest.fixture(scope="session") +def example_data_dir(): + """Return the path to the example_data directory.""" + return os.path.abspath(EXAMPLE_DATA_DIR) + + +@pytest.fixture(scope="session") +def mapping_file_sc(example_data_dir): + """Return the path to the QTL mapping file.""" + return os.path.join(example_data_dir, "mapping_file_test.csv") + + +@pytest.fixture(scope="session") +def qtl_tiledb(tmp_path_factory, example_data_dir, mapping_file_sc): + """Create a QTL TileDB from example data and return its path. + + This fixture runs once per test session and reuses the same TileDB. + """ + from tdbsumstat.utils.harmonize_ingest import Harmonize + + uri = str(tmp_path_factory.mktemp("tiledb") / "test_qtl_tiledb") + + h = Harmonize( + mapping_file=mapping_file_sc, + uri=uri, + type_sumstat="qtl", + pvar_file=None, + type_trait="quant", + mac=None, + maf=None, + permuted=False, + ) + h.create_tiledb() + h.create_mapping() + + # Ingest both example files + data_files = [ + os.path.join(example_data_dir, "dummy_out_ENSG0000010000.tsv.gz"), + os.path.join(example_data_dir, "dummy_out_ENSG0000010001.tsv.gz"), + ] + + for filepath in data_files: + chunk_pl = pl.read_csv(filepath, separator="\t", low_memory=True, null_values="NA") + # Extract gene from filename: dummy_out_ENSG0000010000.tsv.gz -> ENSG0000010000 + gene = os.path.basename(filepath).replace("dummy_out_", "").split(".")[0] + h.harmonize(sumstat=chunk_pl, cell="T_gd", gene=gene, n=4000, pheno_var=1.5) + h.ingest_data(file_path=filepath) + h.create_metadata(file_path=filepath) + + h.merge_metadata_files() + return uri + + +@pytest.fixture(scope="session") +def qtl_metadata_df(qtl_tiledb): + """Return the metadata DataFrame for the QTL TileDB.""" + import json + + with tiledb.open(qtl_tiledb, mode="r") as A: + metadata = json.loads(A.meta["merged_metadata"]) + + rows = [] + for cell in metadata["CELL"]: + for chrom, genes in metadata[cell].items(): + for gene, stats in genes.items(): + rows.append({"CELL": cell, "CHR": chrom, "GENE": gene, **stats}) + df_meta = pl.DataFrame(rows) + df_meta = df_meta.with_columns(pl.col("CHR").cast(pl.UInt16)) + return df_meta + + +@pytest.fixture() +def tmp_out(tmp_path): + """Return a temporary output prefix for test files.""" + return str(tmp_path / "out") diff --git a/tests/test_export.py b/tests/test_export.py new file mode 100644 index 0000000..d92cea5 --- /dev/null +++ b/tests/test_export.py @@ -0,0 +1,147 @@ +"""Tests for the export handler functions (snp, regions, locusbreaker, metadata, traits).""" +import os + +import pandas as pd +import polars as pl +import pytest +import tiledb + +from tdbsumstat.cli.export.regions import export_by_regions +from tdbsumstat.cli.export.snp import export_by_snp + +EXAMPLE_DATA_DIR = os.path.join(os.path.dirname(__file__), "..", "example_data") + + +class TestExportByRegions: + def test_qtl_regions_output(self, qtl_tiledb, tmp_out): + """Export by regions should create a non-empty CSV for known regions.""" + region_file = os.path.join(EXAMPLE_DATA_DIR, "region_list_sc.csv") + with tiledb.open(qtl_tiledb, mode="r") as tdb: + export_by_regions( + tiledb_export=tdb, + table_regions=region_file, + attr="P,SNPID,EAF,BETA,SE", + type_sumstat="qtl", + out=tmp_out + "_regions.csv", + ) + + output_file = tmp_out + "_regions.csv" + if os.path.exists(output_file): + df = pd.read_csv(output_file) + assert len(df) > 0 + assert "P" in df.columns + + def test_empty_region_produces_no_file(self, qtl_tiledb, tmp_out, tmp_path): + """Querying a region with no matching gene should not create an output file.""" + empty_region_file = str(tmp_path / "empty_region.csv") + # Use valid CHR/cell but a gene that doesn't exist in example data + pd.DataFrame({ + "CHR": [20], + "START": [1], + "END": [100], + "TRAIT": ["T_gd:ENSG9999999999"], + }).to_csv(empty_region_file, index=False) + + out_file = tmp_out + "_empty.csv" + with tiledb.open(qtl_tiledb, mode="r") as tdb: + export_by_regions( + tiledb_export=tdb, + table_regions=empty_region_file, + attr="P,SNPID,EAF,BETA,SE", + type_sumstat="qtl", + out=out_file, + ) + # Should not have created a file (no data matched) + assert not os.path.exists(out_file) + + +class TestExportBySnp: + def test_qtl_snp_output(self, qtl_tiledb, tmp_out): + """Export by SNP list should create a CSV with matching rows.""" + snp_file = os.path.join(EXAMPLE_DATA_DIR, "snp_list_sc.csv") + with tiledb.open(qtl_tiledb, mode="r") as tdb: + export_by_snp( + tiledb_export=tdb, + snp=snp_file, + attr="P,SNPID,EAF,BETA,SE", + type_sumstat="qtl", + out=tmp_out, + ) + # The output file(s) are named {out}_{trait}_{chrom}.csv + output_files = [ + f for f in os.listdir(os.path.dirname(tmp_out) or ".") + if f.endswith(".csv") + ] + assert len(output_files) > 0 + + +class TestLocusbreakerExport: + def test_locusbreaker_import(self): + """Locusbreaker module should be importable without errors.""" + from tdbsumstat.cli.export.locusbreaker import export_with_locusbreaker # noqa: F401 + + +class TestMetadataExport: + def test_export_metadata_creates_file(self, qtl_tiledb, tmp_out): + """export_metadata should create a *_meta.csv file.""" + from tdbsumstat.cli.export.metadata import export_metadata + + export_metadata(qtl_tiledb, "qtl", tmp_out) + assert os.path.exists(tmp_out + "_meta.csv") + df = pd.read_csv(tmp_out + "_meta.csv") + assert len(df) > 0 + + def test_recompute_metadata_import(self): + """recompute_metadata should be importable without errors.""" + from tdbsumstat.cli.export.metadata import recompute_metadata # noqa: F401 + + +class TestExportByTraits: + def test_export_by_traits_import(self): + """export_by_traits should be importable without errors.""" + from tdbsumstat.cli.export.traits import export_by_traits # noqa: F401 + + def test_export_by_traits_qtl(self, qtl_tiledb, tmp_out): + """Export by traits should run without errors.""" + from tdbsumstat.cli.export.traits import export_by_traits + + trait_file = str(os.path.join(os.path.dirname(tmp_out), "trait_list.csv")) + pd.DataFrame({"TRAIT": ["T_gd:ENSG0000010000"]}).to_csv(trait_file, index=False) + + export_by_traits( + uri_path=qtl_tiledb, + trait_list=trait_file, + attr="P,SNPID,EAF,BETA,SE", + type_sumstat="qtl", + out=tmp_out, + batch_name="test", + ) + # The function completes without error; output may be empty for small example data + + +class TestModuleImports: + """Smoke tests: ensure all new modules can be imported cleanly.""" + + def test_import_helpers(self): + from tdbsumstat.cli.export.helpers import open_tiledb_and_load_metadata # noqa: F401 + + def test_import_snp(self): + from tdbsumstat.cli.export.snp import export_by_snp # noqa: F401 + + def test_import_regions(self): + from tdbsumstat.cli.export.regions import export_by_regions # noqa: F401 + + def test_import_locusbreaker(self): + from tdbsumstat.cli.export.locusbreaker import export_with_locusbreaker # noqa: F401 + + def test_import_metadata(self): + from tdbsumstat.cli.export.metadata import export_metadata, recompute_metadata # noqa: F401 + + def test_import_traits(self): + from tdbsumstat.cli.export.traits import export_by_traits # noqa: F401 + + def test_import_command(self): + from tdbsumstat.cli.export.command import export # noqa: F401 + + def test_import_export_package(self): + from tdbsumstat.cli.export import export # noqa: F401 diff --git a/tests/test_harmonize.py b/tests/test_harmonize.py new file mode 100644 index 0000000..86c7141 --- /dev/null +++ b/tests/test_harmonize.py @@ -0,0 +1,156 @@ +"""Tests for the Harmonize class (harmonize_ingest.py).""" +import os + +import numpy as np +import polars as pl +import pytest +import tiledb + +from tdbsumstat.utils.harmonize_ingest import Harmonize, HarmonizationError + + +EXAMPLE_DATA_DIR = os.path.join(os.path.dirname(__file__), "..", "example_data") + + +@pytest.fixture() +def mapping_file(): + return os.path.join(EXAMPLE_DATA_DIR, "mapping_file_test.csv") + + +@pytest.fixture() +def sample_qtl_df(): + """Minimal QTL polars DataFrame mimicking the example data columns.""" + return pl.DataFrame({ + "Chr": [20, 20, 20], + "Gene": ["ENSG0000010000", "ENSG0000010000", "ENSG0000010000"], + "cell.type": ["T_gd", "T_gd", "T_gd"], + "pos": [100, 200, 300], + "a0": ["A", "C", "G"], + "a1": ["T", "G", "A"], + "p": [0.01, 0.5, 0.001], + "N": [500, 500, 500], + "beta": [0.1, -0.2, 0.3], + "se": [0.05, 0.08, 0.04], + }) + + +class TestCreateMapping: + def test_valid_mapping(self, mapping_file): + h = Harmonize(mapping_file, "dummy", "qtl", None, "quant", None, None, False) + h.create_mapping() + assert "CHR" in h.mapping_types.values() + assert "BETA" in h.mapping_types.values() + assert "SE" in h.mapping_types.values() + + def test_missing_beta_se_raises(self, tmp_path): + bad_mapping = tmp_path / "bad_mapping.csv" + bad_mapping.write_text("Chr,CHR\npos,POS\n") + h = Harmonize(str(bad_mapping), "dummy", "qtl", None, "quant", None, None, False) + with pytest.raises(HarmonizationError, match="BETA and SE"): + h.create_mapping() + + def test_empty_mapping_raises(self, tmp_path): + empty_file = tmp_path / "empty.csv" + empty_file.write_text("") + h = Harmonize(str(empty_file), "dummy", "qtl", None, "quant", None, None, False) + with pytest.raises(HarmonizationError, match="empty or not formatted"): + h.create_mapping() + + +class TestCreateTileDB: + def test_creates_qtl_tiledb(self, mapping_file, tmp_path): + uri = str(tmp_path / "test_tiledb") + h = Harmonize(mapping_file, uri, "qtl", None, "quant", None, None, False) + h.create_tiledb() + assert tiledb.array_exists(uri) + schema = tiledb.ArraySchema.load(uri) + dim_names = [schema.domain.dim(i).name for i in range(schema.domain.ndim)] + assert "CHR" in dim_names + assert "CELL" in dim_names + assert "GENE" in dim_names + assert "POS" in dim_names + + def test_creates_gwas_tiledb(self, mapping_file, tmp_path): + uri = str(tmp_path / "test_gwas") + h = Harmonize(mapping_file, uri, "gwas", None, "quant", None, None, False) + h.create_tiledb() + assert tiledb.array_exists(uri) + schema = tiledb.ArraySchema.load(uri) + dim_names = [schema.domain.dim(i).name for i in range(schema.domain.ndim)] + assert "TRAIT" in dim_names + assert "CHR" in dim_names + assert "POS" in dim_names + + +class TestHarmonize: + def test_harmonize_qtl_adds_cell_gene(self, mapping_file, sample_qtl_df): + h = Harmonize(mapping_file, "dummy", "qtl", None, "quant", None, None, False) + h.create_mapping() + h.harmonize(sumstat=sample_qtl_df, cell="T_gd", gene="ENSG0000010000", n=500, pheno_var=1.5) + assert "CELL" in h.chunk_pl.columns + assert "GENE" in h.chunk_pl.columns + assert "SNPID" in h.chunk_pl.columns + + def test_harmonize_snpid_format(self, mapping_file, sample_qtl_df): + h = Harmonize(mapping_file, "dummy", "qtl", None, "quant", None, None, False) + h.create_mapping() + h.harmonize(sumstat=sample_qtl_df, cell="T_gd", gene="ENSG0000010000", n=500, pheno_var=1.5) + # All SNPIDs should start with 'chr' + snpids = h.chunk_pl["SNPID"].to_list() + assert all(s.startswith("chr") for s in snpids) + + def test_harmonize_raises_without_n(self, mapping_file, sample_qtl_df): + df_no_n = sample_qtl_df.drop("N") + h = Harmonize(mapping_file, "dummy", "qtl", None, "quant", None, None, False) + h.create_mapping() + with pytest.raises(HarmonizationError): + h.harmonize(sumstat=df_no_n, cell="T_gd", gene="ENSG0000010000", pheno_var=1.5) + + def test_harmonize_maf_filter(self, mapping_file, sample_qtl_df): + """MAF filter should remove rows with EAF outside the range.""" + # Add EAF column: use a0/a1 encoded EAF from original data, but override + df_with_eaf = sample_qtl_df.with_columns(pl.lit(0.01).alias("EAF_explicit")) + h = Harmonize(mapping_file, "dummy", "qtl", None, "quant", None, maf=0.05, permuted=False) + h.create_mapping() + # With maf=0.05 and EAF derived from alleles, some rows may be filtered + # Just make sure the call doesn't crash + h.harmonize(sumstat=sample_qtl_df, cell="T_gd", gene="ENSG0000010000", n=500, pheno_var=1.5) + + def test_binary_trait_adds_n_columns(self, mapping_file, sample_qtl_df): + h = Harmonize(mapping_file, "dummy", "gwas", None, "binary", None, None, False) + h.create_mapping() + gwas_df = sample_qtl_df.rename({"cell.type": "TRAIT_col", "Gene": "TRAIT"}).drop("Gene", strict=False) + # Use a simplified gwas-like df + gwas_df = pl.DataFrame({ + "Chr": [1, 1], + "pos": [100, 200], + "a0": ["A", "C"], + "a1": ["T", "G"], + "p": [0.01, 0.5], + "beta": [0.1, -0.2], + "se": [0.05, 0.08], + "N": [500, 500], + "Gene": ["T1", "T1"], + "cell.type": ["gwas", "gwas"], + }) + mapping_gwas = mapping_file # mapping is for QTL, adapt + h2 = Harmonize(mapping_gwas, "dummy", "gwas", None, "binary", None, None, False) + h2.create_mapping() + h2.harmonize( + sumstat=gwas_df, + trait="T1", + n_cases=200, + n_controls=300, + pheno_var=1.0, + ) + assert "N_CASES" in h2.chunk_pl.columns + assert "N_CONTROLS" in h2.chunk_pl.columns + + +class TestIngestData: + def test_ingest_creates_data(self, qtl_tiledb): + """The session-scoped qtl_tiledb fixture should have rows.""" + with tiledb.open(qtl_tiledb, mode="r") as A: + df = A.query(dims=["CHR", "CELL", "GENE", "POS"]).df[:] + assert len(df) > 0 + assert "CELL" in df.columns diff --git a/tests/test_ingest.py b/tests/test_ingest.py new file mode 100644 index 0000000..9f75c4b --- /dev/null +++ b/tests/test_ingest.py @@ -0,0 +1,391 @@ +"""Tests for the refactored ingestion modules under tdbsumstat/utils/ingest/.""" +import json +import os + +import polars as pl +import pytest +import tiledb + +from tdbsumstat.utils.ingest import Harmonize, HarmonizationError +from tdbsumstat.utils.ingest.errors import HarmonizationError as DirectError +from tdbsumstat.utils.ingest.schema import SchemaMixin +from tdbsumstat.utils.ingest.mapping import MappingMixin +from tdbsumstat.utils.ingest.harmonize import HarmonizeMixin +from tdbsumstat.utils.ingest.writer import WriterMixin +from tdbsumstat.utils.ingest.metadata import MetadataMixin + +EXAMPLE_DATA_DIR = os.path.join(os.path.dirname(__file__), "..", "example_data") + + +# --------------------------------------------------------------------------- +# Helpers / fixtures +# --------------------------------------------------------------------------- + +@pytest.fixture() +def mapping_file(): + return os.path.join(EXAMPLE_DATA_DIR, "mapping_file_test.csv") + + +@pytest.fixture() +def sample_qtl_df(): + """Minimal QTL Polars DataFrame matching the mapping_file_test column names.""" + return pl.DataFrame({ + "Chr": [20, 20, 20], + "Gene": ["ENSG0000010000"] * 3, + "cell.type": ["T_gd"] * 3, + "pos": [100, 200, 300], + "a0": ["A", "C", "G"], + "a1": ["T", "G", "A"], + "p": [0.01, 0.5, 0.001], + "N": [500, 500, 500], + "beta": [0.1, -0.2, 0.3], + "se": [0.05, 0.08, 0.04], + }) + + +@pytest.fixture() +def empty_qtl_df(): + """Empty QTL Polars DataFrame with correct schema.""" + return pl.DataFrame({ + "Chr": pl.Series([], dtype=pl.Int64), + "Gene": pl.Series([], dtype=pl.Utf8), + "cell.type": pl.Series([], dtype=pl.Utf8), + "pos": pl.Series([], dtype=pl.Int64), + "a0": pl.Series([], dtype=pl.Utf8), + "a1": pl.Series([], dtype=pl.Utf8), + "p": pl.Series([], dtype=pl.Float64), + "N": pl.Series([], dtype=pl.Int64), + "beta": pl.Series([], dtype=pl.Float64), + "se": pl.Series([], dtype=pl.Float64), + }) + + +# --------------------------------------------------------------------------- +# SchemaMixin +# --------------------------------------------------------------------------- + +class TestSchemaMixin: + def test_qtl_dimensions(self, mapping_file, tmp_path): + uri = str(tmp_path / "qtl") + h = Harmonize(mapping_file, uri, "qtl", None, "quant", None, None, False) + h.create_tiledb() + schema = tiledb.ArraySchema.load(uri) + dim_names = [schema.domain.dim(i).name for i in range(schema.domain.ndim)] + assert dim_names == ["CHR", "CELL", "GENE", "POS"] + attr_names = [schema.attr(i).name for i in range(schema.nattr)] + assert "DIST" in attr_names + + def test_gwas_dimensions(self, mapping_file, tmp_path): + uri = str(tmp_path / "gwas") + h = Harmonize(mapping_file, uri, "gwas", None, "quant", None, None, False) + h.create_tiledb() + schema = tiledb.ArraySchema.load(uri) + dim_names = [schema.domain.dim(i).name for i in range(schema.domain.ndim)] + assert dim_names == ["CHR", "TRAIT", "POS"] + attr_names = [schema.attr(i).name for i in range(schema.nattr)] + assert "DIST" not in attr_names + + def test_sparse_schema(self, mapping_file, tmp_path): + uri = str(tmp_path / "sparse_check") + h = Harmonize(mapping_file, uri, "qtl", None, "quant", None, None, False) + h.create_tiledb() + schema = tiledb.ArraySchema.load(uri) + assert schema.sparse is True + + +# --------------------------------------------------------------------------- +# MappingMixin +# --------------------------------------------------------------------------- + +class TestMappingMixin: + def test_creates_dict(self, mapping_file): + h = Harmonize(mapping_file, "dummy", "qtl", None, "quant", None, None, False) + h.create_mapping() + assert isinstance(h.mapping_types, dict) + assert len(h.mapping_types) > 0 + + def test_missing_beta_raises(self, tmp_path): + f = tmp_path / "m.csv" + f.write_text("Chr,CHR\npos,POS\n") + h = Harmonize(str(f), "dummy", "qtl", None, "quant", None, None, False) + with pytest.raises(HarmonizationError, match="BETA and SE"): + h.create_mapping() + + def test_empty_file_raises(self, tmp_path): + f = tmp_path / "empty.csv" + f.write_text("") + h = Harmonize(str(f), "dummy", "qtl", None, "quant", None, None, False) + with pytest.raises(HarmonizationError, match="empty or not formatted"): + h.create_mapping() + + def test_harmonization_error_importable_directly(self): + assert DirectError is HarmonizationError + + +# --------------------------------------------------------------------------- +# HarmonizeMixin +# --------------------------------------------------------------------------- + +class TestHarmonizeMixin: + def test_snpid_prefixed_with_chr(self, mapping_file, sample_qtl_df): + h = Harmonize(mapping_file, "dummy", "qtl", None, "quant", None, None, False) + h.create_mapping() + h.harmonize(sumstat=sample_qtl_df, cell="T_gd", gene="ENSG0000010000", n=500, pheno_var=1.5) + for snpid in h.chunk_pl["SNPID"].to_list(): + assert snpid.startswith("chr"), f"SNPID {snpid!r} does not start with 'chr'" + + def test_cell_and_gene_columns_added(self, mapping_file, sample_qtl_df): + h = Harmonize(mapping_file, "dummy", "qtl", None, "quant", None, None, False) + h.create_mapping() + h.harmonize(sumstat=sample_qtl_df, cell="T_gd", gene="ENSG0000010000", n=500, pheno_var=1.5) + assert "CELL" in h.chunk_pl.columns + assert "GENE" in h.chunk_pl.columns + assert h.chunk_pl["CELL"].unique().to_list() == ["T_gd"] + assert h.chunk_pl["GENE"].unique().to_list() == ["ENSG0000010000"] + + def test_p_value_column_present(self, mapping_file, sample_qtl_df): + h = Harmonize(mapping_file, "dummy", "qtl", None, "quant", None, None, False) + h.create_mapping() + h.harmonize(sumstat=sample_qtl_df, cell="T_gd", gene="ENSG0000010000", n=500, pheno_var=1.5) + assert "P" in h.chunk_pl.columns + assert all(0 <= p <= 1 for p in h.chunk_pl["P"].to_list()) + + def test_missing_n_raises(self, mapping_file, sample_qtl_df): + h = Harmonize(mapping_file, "dummy", "qtl", None, "quant", None, None, False) + h.create_mapping() + with pytest.raises(HarmonizationError): + h.harmonize(sumstat=sample_qtl_df.drop("N"), cell="T_gd", + gene="ENSG0000010000", pheno_var=1.5) + + def test_maf_filter_reduces_rows(self, mapping_file, sample_qtl_df): + """All rows in sample have EAF=0 (default), so MAF=0; maf=0.1 should drop all.""" + h = Harmonize(mapping_file, "dummy", "qtl", None, "quant", None, maf=0.1, permuted=False) + h.create_mapping() + h.harmonize(sumstat=sample_qtl_df, cell="T_gd", gene="ENSG0000010000", n=500, pheno_var=1.5) + # With maf=0.1 all rows may be filtered out (EAF defaults to 0) + assert h.chunk_pl.height >= 0 # just confirm no crash + + def test_binary_trait_n_columns(self, mapping_file, sample_qtl_df): + h = Harmonize(mapping_file, "dummy", "gwas", None, "binary", None, None, False) + h.create_mapping() + gwas_df = pl.DataFrame({ + "Chr": [1, 1], + "pos": [100, 200], + "a0": ["A", "C"], + "a1": ["T", "G"], + "p": [0.01, 0.5], + "beta": [0.1, -0.2], + "se": [0.05, 0.08], + "N": [500, 500], + "Gene": ["T1", "T1"], + "cell.type": ["gwas", "gwas"], + }) + h.harmonize(sumstat=gwas_df, trait="T1", n_cases=200, n_controls=300, pheno_var=1.0) + assert "N_CASES" in h.chunk_pl.columns + assert "N_CONTROLS" in h.chunk_pl.columns + + def test_invalid_type_trait_raises(self, mapping_file, sample_qtl_df): + h = Harmonize(mapping_file, "dummy", "qtl", None, "invalid_type", None, None, False) + h.create_mapping() + with pytest.raises(HarmonizationError, match="binary or quant"): + h.harmonize(sumstat=sample_qtl_df, cell="T_gd", gene="ENSG0000010000", n=500, pheno_var=1.5) + + def test_empty_dataframe_harmonizes_without_crash(self, mapping_file, empty_qtl_df): + """Harmonizing an empty DataFrame should not raise and should produce an empty chunk_pl.""" + h = Harmonize(mapping_file, "dummy", "qtl", None, "quant", None, None, False) + h.create_mapping() + h.harmonize(sumstat=empty_qtl_df, cell="T_gd", gene="ENSG0000010000", n=500, pheno_var=1.5) + assert h.chunk_pl.height == 0 + + +# --------------------------------------------------------------------------- +# WriterMixin +# --------------------------------------------------------------------------- + +class TestWriterMixin: + def test_ingest_appends_rows(self, mapping_file, sample_qtl_df, tmp_path): + uri = str(tmp_path / "writer_test") + h = Harmonize(mapping_file, uri, "qtl", None, "quant", None, None, False) + h.create_tiledb() + h.create_mapping() + h.harmonize(sumstat=sample_qtl_df, cell="T_gd", gene="ENSG0000010000", n=500, pheno_var=1.5) + h.ingest_data(file_path="dummy_file.tsv") + + with tiledb.open(uri, mode="r") as A: + df = A.query(dims=["CHR", "CELL", "GENE", "POS"]).df[:] + assert len(df) > 0 + + def test_duplicates_are_removed(self, mapping_file, tmp_path): + """Rows sharing an index key (CHR, POS, CELL, GENE) are ALL dropped. + + The ingestion pipeline treats ambiguous duplicate positions as + unreliable and excludes them entirely rather than keeping one. + """ + uri = str(tmp_path / "dedup_test") + h = Harmonize(mapping_file, uri, "qtl", None, "quant", None, None, False) + h.create_tiledb() + h.create_mapping() + + # Two identical rows + dup_df = pl.DataFrame({ + "Chr": [20, 20], + "Gene": ["ENSG0000010000", "ENSG0000010000"], + "cell.type": ["T_gd", "T_gd"], + "pos": [500, 500], # same position → duplicate + "a0": ["A", "A"], + "a1": ["T", "T"], + "p": [0.01, 0.01], + "N": [500, 500], + "beta": [0.1, 0.1], + "se": [0.05, 0.05], + }) + h.harmonize(sumstat=dup_df, cell="T_gd", gene="ENSG0000010000", n=500, pheno_var=1.5) + h.ingest_data(file_path="dup_file.tsv") + + with tiledb.open(uri, mode="r") as A: + df = A.query(dims=["CHR", "CELL", "GENE", "POS"]).df[:] + # Both rows are duplicate; they should both be dropped by the dedup logic + assert len(df) == 0 + + +# --------------------------------------------------------------------------- +# MetadataMixin +# --------------------------------------------------------------------------- + +class TestMetadataMixin: + def _create_ingested_tiledb(self, mapping_file, sample_qtl_df, tmp_path): + """Helper: create + ingest + return a Harmonize object with data.""" + uri = str(tmp_path / "meta_test") + h = Harmonize(mapping_file, uri, "qtl", None, "quant", None, None, False) + h.create_tiledb() + h.create_mapping() + h.harmonize(sumstat=sample_qtl_df, cell="T_gd", gene="ENSG0000010000", n=500, pheno_var=1.5) + h.ingest_data(file_path="file.tsv") + return h + + def test_create_metadata_writes_json(self, mapping_file, sample_qtl_df, tmp_path): + h = self._create_ingested_tiledb(mapping_file, sample_qtl_df, tmp_path) + h.create_metadata(file_path="file.tsv") + + metadata_dir = h.uri + "_metadata_parts" + json_files = list(os.listdir(metadata_dir)) + assert len(json_files) == 1 + assert json_files[0].endswith(".json") + + def test_metadata_json_has_cell_key(self, mapping_file, sample_qtl_df, tmp_path): + h = self._create_ingested_tiledb(mapping_file, sample_qtl_df, tmp_path) + h.create_metadata(file_path="file.tsv") + + metadata_dir = h.uri + "_metadata_parts" + json_file = os.path.join(metadata_dir, os.listdir(metadata_dir)[0]) + with open(json_file) as f: + meta = json.load(f) + assert "CELL" in meta + assert "T_gd" in meta["CELL"] + + def test_merge_metadata_stores_in_tiledb(self, mapping_file, sample_qtl_df, tmp_path): + h = self._create_ingested_tiledb(mapping_file, sample_qtl_df, tmp_path) + h.create_metadata(file_path="file.tsv") + h.merge_metadata_files() + + with tiledb.open(h.uri, mode="r") as A: + merged = json.loads(A.meta["merged_metadata"]) + assert "CELL" in merged + assert "T_gd" in merged["CELL"] + + def test_merge_metadata_static_helper(self): + """_merge_single_metadata should correctly merge QTL entries.""" + merged = {"traits": [], "CELL": []} + file_meta = { + "CELL": ["T_gd"], + "T_gd": { + "20": {"ENSG0000010000": {"ACAT": 0.5, "N": 500.0, "PHENO_VAR": 1.5, "MIN_P": 0.001}} + }, + } + MetadataMixin._merge_single_metadata(merged, file_meta) + assert "T_gd" in merged["CELL"] + assert "20" in merged["T_gd"] + assert "ENSG0000010000" in merged["T_gd"]["20"] + + def test_export_metadata_to_csv(self, mapping_file, sample_qtl_df, tmp_path): + h = self._create_ingested_tiledb(mapping_file, sample_qtl_df, tmp_path) + h.create_metadata(file_path="file.tsv") + h.merge_metadata_files() + + import pandas as pd + df = h.export_metadata_to_csv() + assert isinstance(df, pd.DataFrame) + assert len(df) > 0 + assert "CELL" in df.columns + + +# --------------------------------------------------------------------------- +# End-to-end ingestion using example data files +# --------------------------------------------------------------------------- + +class TestEndToEndIngestion: + def test_full_qtl_pipeline(self, mapping_file, tmp_path): + """Full QTL ingestion pipeline using example data files.""" + uri = str(tmp_path / "e2e_qtl") + h = Harmonize(mapping_file, uri, "qtl", None, "quant", None, None, False) + h.create_tiledb() + h.create_mapping() + + data_files = [ + (os.path.join(EXAMPLE_DATA_DIR, "dummy_out_ENSG0000010000.tsv.gz"), "ENSG0000010000"), + (os.path.join(EXAMPLE_DATA_DIR, "dummy_out_ENSG0000010001.tsv.gz"), "ENSG0000010001"), + ] + + for filepath, gene in data_files: + chunk_pl = pl.read_csv(filepath, separator="\t", low_memory=True, null_values="NA") + h.harmonize(sumstat=chunk_pl, cell="Tgd", gene=gene, n=4000, pheno_var=1.5) + h.ingest_data(file_path=filepath) + h.create_metadata(file_path=filepath) + + h.merge_metadata_files() + + # Verify data was written + with tiledb.open(uri, mode="r") as A: + df = A.query(dims=["CHR", "CELL", "GENE", "POS"]).df[:] + assert len(df) > 0 + + # Verify merged metadata + with tiledb.open(uri, mode="r") as A: + merged = json.loads(A.meta["merged_metadata"]) + assert "Tgd" in merged["CELL"] + + def test_backward_compat_import(self): + """harmonize_ingest shim must re-export the same Harmonize class.""" + from tdbsumstat.utils.harmonize_ingest import Harmonize as OldHarmonize + from tdbsumstat.utils.ingest import Harmonize as NewHarmonize + assert OldHarmonize is NewHarmonize + + +# --------------------------------------------------------------------------- +# Module smoke-tests +# --------------------------------------------------------------------------- + +class TestModuleImports: + def test_import_errors(self): + from tdbsumstat.utils.ingest.errors import HarmonizationError # noqa: F401 + + def test_import_schema(self): + from tdbsumstat.utils.ingest.schema import SchemaMixin # noqa: F401 + + def test_import_mapping(self): + from tdbsumstat.utils.ingest.mapping import MappingMixin # noqa: F401 + + def test_import_harmonize(self): + from tdbsumstat.utils.ingest.harmonize import HarmonizeMixin # noqa: F401 + + def test_import_qc(self): + from tdbsumstat.utils.ingest.qc import QCMixin # noqa: F401 + + def test_import_writer(self): + from tdbsumstat.utils.ingest.writer import WriterMixin # noqa: F401 + + def test_import_metadata(self): + from tdbsumstat.utils.ingest.metadata import MetadataMixin # noqa: F401 + + def test_import_package(self): + from tdbsumstat.utils.ingest import Harmonize, HarmonizationError # noqa: F401 diff --git a/tests/test_utils.py b/tests/test_utils.py new file mode 100644 index 0000000..a3c0359 --- /dev/null +++ b/tests/test_utils.py @@ -0,0 +1,121 @@ +"""Tests for utility functions (acat_optimized, compute_pheno_variance, z_to_p_via_chi2).""" +import math + +import numpy as np +import polars as pl +import pytest + +from tdbsumstat.utils import acat_optimized, compute_pheno_variance, z_to_p_via_chi2 + + +class TestAcatOptimized: + def test_uniform_pvalues(self): + """ACAT of many uniform p-values should be close to 0.5.""" + pvals = pl.Series([0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9]) + result = acat_optimized(pvals) + assert 0.0 <= result <= 1.0 + + def test_very_small_pvalue_list(self): + """A single very small p-value should produce a small ACAT.""" + pvals = pl.Series([1e-20]) + result = acat_optimized(pvals) + assert result < 1e-10 + + def test_all_ones(self): + """p-values of 1 should produce ACAT close to 1.""" + pvals = pl.Series([1.0, 1.0, 1.0]) + result = acat_optimized(pvals) + assert result > 0.9 + + def test_accepts_list(self): + """acat_optimized should accept plain Python lists.""" + pvals = [0.05, 0.1, 0.2] + result = acat_optimized(pvals) + assert 0.0 <= result <= 1.0 + + def test_invalid_type_raises(self): + """Non-Series / non-list input should raise TypeError.""" + with pytest.raises(TypeError): + acat_optimized(np.array([0.05, 0.1])) + + def test_out_of_range_raises(self): + """p-values outside [0, 1] should raise ValueError.""" + pvals = pl.Series([0.5, 1.5]) + with pytest.raises(ValueError): + acat_optimized(pvals) + + def test_nan_values_ignored(self): + """NaN p-values should be silently ignored.""" + pvals = pl.Series([0.05, float("nan"), 0.1]) + result = acat_optimized(pvals) + assert 0.0 <= result <= 1.0 + + def test_all_nan_returns_nan(self): + """All-NaN input should return NaN.""" + pvals = pl.Series([float("nan"), float("nan")]) + result = acat_optimized(pvals) + assert math.isnan(result) + + def test_small_pvalue_approximation(self): + """Values below 1e-15 should use 1/(pi*p) approximation without crashing.""" + pvals = pl.Series([1e-300, 0.05]) + result = acat_optimized(pvals) + assert result < 0.05 # very small p drives ACAT down + + +class TestComputePhenoVariance: + def _make_quant_df(self, n=500, eaf=0.3, se=0.1, beta=0.05): + return pl.DataFrame({ + "N": [n] * 10, + "EAF": [eaf] * 10, + "SE": [se] * 10, + "BETA": [beta] * 10, + }) + + def _make_binary_df(self, n_cases=200, n_controls=300, eaf=0.3, se=0.1, beta=0.05): + return pl.DataFrame({ + "N_CASES": [float(n_cases)] * 10, + "N_CONTROLS": [float(n_controls)] * 10, + "EAF": [eaf] * 10, + "SE": [se] * 10, + "BETA": [beta] * 10, + }) + + def test_quant_returns_string(self): + df = self._make_quant_df() + result = compute_pheno_variance(df, "quant") + # The function returns a string representation of a float + assert isinstance(result, str) + float(result) # should not raise + + def test_binary_adds_n_column(self): + df = self._make_binary_df() + result = compute_pheno_variance(df, "binary") + assert isinstance(result, str) + float(result) + + def test_quant_positive_variance(self): + df = self._make_quant_df(n=1000, eaf=0.4, se=0.05) + result = float(compute_pheno_variance(df, "quant")) + assert result > 0 + + +class TestZToPViaChi2: + def test_zero_z_gives_one(self): + """z=0 should give p-value of 1.""" + p = z_to_p_via_chi2(0) + assert abs(p - 1.0) < 1e-10 + + def test_large_z_gives_small_p(self): + """Large z-score should give very small p-value.""" + p = z_to_p_via_chi2(10) + assert p < 1e-20 + + def test_z_196_gives_approx_005(self): + """z ≈ 1.96 should give p ≈ 0.05.""" + p = z_to_p_via_chi2(1.96) + assert abs(p - 0.05) < 0.01 + + def test_symmetric(self): + """Positive and negative z should give the same p-value.""" + assert abs(z_to_p_via_chi2(2.5) - z_to_p_via_chi2(-2.5)) < 1e-15